Publications

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dice: nonclinical causes of overtreatment. 20102916481
[genotypic analysis and plant growth-promoting ability of four plant growth-promoting bacteria from mangrove].we identified four strains of plant growth-promoting bacteria (pgpb) and their plant growth-promoting ability.201021141471
exclusion testing for huntington's disease in pregnancy with a closely linked dna marker.55 couples where one partner was at 50% risk of huntington's disease (hd) were investigated with a dna probe closely linked to hd, with a view to exclusion testing in a future pregnancy. in 3 of 9 pregnancies so far, hd was excluded in the absence of recombination. in 3 the risk was raised to around 50%, and in 2 exclusion tests were uninformative. the remaining couple changed their minds about termination of the pregnancy and the test was therefore judged inappropriate.20102884411
[current empirical data on conditions in relation to death in the hospital].this survey-study represents the psycho-social conditions of death in west-german hospitals as seen from different occupational groups. the test, developed for this task, has been applied in 70 hospitals of different federal states, medical-departments and supporters. it is shown that following factors have an essential influence on the attitudes of people to the needs of the dying patient: amount of medical engineering at ward, time of professional activity and status of the personnel. in sum, ...20102798718
Vibrio jasicida sp. nov., a member of the Harveyi clade, from marine animals (packhorse lobster, abalone, and Atlantic salmon).Six isolates of a facultatively anaerobic bacterium were recovered in culture from marine invertebrates and vertebrates, including packhorse lobster (Jasus verreauxi), abalone (Haliotis sp.) and Atlantic salmon (Salmo salar) between 1994 and 2002. The bacteria are Gram-negative, rod shaped and motile by means of more than one polar flagellum, oxidase-positive, catalase-positive and able to grow between 0.5-8.0% NaCl (optimum 3.0-6.0%) and at temperatures of 10-37 °C (optimum 25-30 °C). On the ba ...201121984666
rocky mountain spotted fever--united states, 1987. 20113131657
[enterostoma therapy--a pilot course in the essen education center of the german nursing association]. 20113127632
[duodenal gastrinoma. description of a clinical case]. 20113231322
detection of quorum sensing signal molecules in the family vibrionaceae.the aim of this study was to detect the production of three kinds of quorum sensing (qs) signal molecules, i.e. the n-acyl-homoserine lactone (ahl), the autoinducer-2 (ai-2) and the cholerae autoinducer-1-like (cai-1-like) molecules in 25 vibrionaceae strains.201121395950
valproate-associated hepatotoxicity and its biochemical mechanisms.intake of the anticonvulsant drug valproic acid, or its sodium salt, has been associated with occasional instances of severe and sometimes fatal hepatotoxicity. probably at least 80 cases have occurred worldwide. the syndrome affects perhaps 1 in 10,000 persons taking the drug, and usually develops in the early weeks or months of therapy. most instances have involved children, usually those receiving more than 1 anticonvulsant. multiple cases have occurred in 2 families. the typical presentation ...20113131628
thyroglobulin and 131i uptake of remaining tissue in patients with differentiated carcinoma after thyroidectomy.in 158 thyroidectomized patients with well-differentiated non-metastatic thyroid cancer the results of serum thyroglobulin (tg) determination and 131i uptake values established immediately before radioiodine treatment (19 days after surgery) were compared. in 113 patients (72%) tg was above 6 ng ml-1 (lower limit of detection) and 131i uptake exceeded 2%. in 11 patients (7%) tg was undetectable and 131i uptake less than 2%. in these cases a radioiodine treatment was not performed; the thyroid ab ...20123399222
oxidation of antipsoriatic 10-acyldithranol derivatives and dithranol to 1,8-dihydroxyanthraquinone. 20123369924
the piriformis syndrome. 20123390766
Production and characterization of a novel monoclonal antibody against Vibrio parahaemolyticus F(0)F(1) ATP synthase's delta subunit and its application for rapid identification of the pathogen.We raised monoclonal antibodies (MAbs) against Vibrio parahaemolyticus cell extracts. One of the MAbs, designated MAb-VP34, reacted in enzyme-linked immunosorbent assays (ELISAs) with 140 V. parahaemolyticus strains, regardless of serotype or origin. MAb-VP34 did not detectably react with 96 strains belonging to 27 other Vibrio species (except for Vibrio natriegens) or with 29 non-Vibrio species. These results show that MAb-VP34 is highly specific for V. parahaemolyticus. Western blotting and ma ...201222056232
thymic involvement in acute disseminated histiocytosis x. 20133628861
endotracheal resuscitation of preterm infants at birth. 20133688937
[a comparative study. the older person too is an individual]. 20133850215
the mosaic accessory gene structures of the sxt/r391-like integrative and conjugative elements derived from vibrio spp. isolated from aquatic products and environment in the yangtze river estuary, china.the emergence, resurgence and spread of human food-borne pathogenic vibrios are one of the major contributors to disease burden and mortality particularly in developing countries with disputable sanitary conditions. previous research on pathogenic vibrio cholerae and vibrio parahaemolitycus derived from clinical samples has proposed links between acquisition of virulence and multiple drug resistance traits and intercellular transmissibility of mobile genetic elements in the environment. to date, ...201324074349
draft genome sequence of the fast-growing bacterium vibrio natriegens strain dsmz 759.vibrio natriegens is a gram-negative bacterium known for its extremely short doubling time. here we present the annotated draft genome sequence of vibrio natriegens strain dsmz 759, with the aim of providing insights about its high growth rate.201323969053
draft genome sequence of the fast-growing marine bacterium vibrio natriegens strain atcc 14048.vibrio natriegens bacteria are gram-negative aquatic microorganisms that are found primarily in coastal seawater and sediments and are perhaps best known for their high growth rates (generation time of <10 min). in this study, we report the first sequenced genome of this species, that of the type strain vibrio natriegens atcc 14048, a salt marsh mud isolate from sapelo island, ga.201323929482
genes similar to the vibrio parahaemolyticus virulence-related genes tdh, tlh, and vscc2 occur in other vibrionaceae species isolated from a pristine estuary.detection of the human pathogen vibrio parahaemolyticus often relies on molecular biological analysis of species-specific virulence factor genes. these genes have been employed in determinations of v. parahaemolyticus population numbers and the prevalence of pathogenic v. parahaemolyticus strains. strains of the vibrionaceae species photobacterium damselae, vibrio diabolicus, vibrio harveyi, and vibrio natriegens, as well as strains similar to vibrio tubiashii, were isolated from a pristine salt ...201424212573
universally improving effect of mixed electron donors on the co₂ fixing efficiency of non-photosynthetic microbial communities from marine environments.the universality of improved co₂ fixing upon the addition of mixed electron donors (meds) composed of na₂s, no₂(-), and s₂o₃(2-) to non-photosynthetic microbial communities (npmcs) obtained from 12 locations in four oceans of the world was validated. the co₂ fixing efficiencies of npmcs were universally enhanced by med compared with those obtained using h₂ alone as electron donor, with average increase of about 276%. an increase in microbial inoculation concentration could increase the net amoun ...201425108727
[preparation and purification of anti-ferritin, anti-cytochrome b 5 hybrid antibodies]. 20144122927
an ldla domain-containing c-type lectin is involved in the innate immunity of eriocheir sinensis.c-type lectins (ctls) have crucial functions in recognizing and eliminating pathogens in innate immunity. this study identified a novel low-density lipoprotein receptor class a (ldla) domain-containing ctl, designated as esctldcp, from the chinese mitten crab eriocheir sinensis. the esctldcp cdna is 1258 bp long, with a 975 bp open reading frame that encodes a 324-amino acid protein. esctldcp contains a signal peptide, an ldla, and a single c-type lectin-like domain. esctldcp was only expressed ...201424140432
[conservative treatment of injuries of the liver]. 20143911104
function of two novel single-crd containing c-type lectins in innate immunity from eriocheir sinensis.c-type lectin is one of the pattern-recognition proteins of the non-self-innate immune system in invertebrates. in this study, two novel c-type lectin cdnas (esctl1 and esctl2) of eriocheir sinensis were cloned and characterized. esctl1 has 169 amino acids, whereas esctl2 has 164 amino acids. these two lectins contain one carbohydrate-recognition domain. phylogenetic analysis showed that esctl1 and esctl2 were not clustered with other reported lectins from crabs. esctl1 and esctl2 were expressed ...201424561128
some acoustic evidence for vocal abuse in adult speakers with repaired cleft palate.acoustic evidence for vocal abuse in adult speakers with cleft palate and hypernasality has not been reported. this study was undertaken to determine if there was acoustic evidence of inappropriate vocal fold adduction during stop consonant production in this population. the results indicated that spectrograms of speakers without cleft palate and severe hypernasality exhibited acoustic characteristics different from spectrograms of speakers without cleft palate and speakers with cleft palate and ...20144010425
[transvaal pedagogic discussion group. the ward nurse as a pedagogue]. 20154483653
[case of pie (pulmonary infiltrate with eosinophilia) syndrome caused by candida]. 20154477881
what is behind our masks? 20154495375
ly-4, a new locus determining a lymphocyte cell-surface alloantigen in mice.a new locus is described that determines an alloantigen on the surface of lymphocytes. it differs from loci previously described in that the corresponding antibody, at least in most antisera, reacts almost exclusively with node lymphocytes, and weakly or not at all with thymuslymphocytes. positive strains include c57bl/6, c57bl/10, c57l, c57br/cd, and rf; negative strains include balb/c, c3h, and sjl. the symbol ly-4 is assigned, with the c57bl/6 allele being ly-4(b), and the balb/c allele ly-4( ...20154515607
[screening and identification of a bacterium capable of converting agar to neoagaro oligosaccharides].to screen and identify a bacterium capable of converting agar to neoagaro oligosaccharides.201526762025
a novel integrin function in innate immunity from chinese mitten crab (eriocheir sinensis).integrins belong to a superfamily of conserved α β heterodimeric cell surface receptors that have critical function in cell migration, differentiation, and survival. in this study, an integrin called esintegrin was identified from chinese mitten crab eriocheir sinensis. esintegrin cdna is 4415 bp long with a 2457 bp open reading frame that encodes an 818 amino acid protein. esintegrin contains a signal peptide, an integrin beta subunit (n-terminal portion of extracellular region) inb domain, an ...201526004499
sulfated phenolic acids from dasycladales siphonous green algae.sulfated aromatic acids play a central role as mediators of chemical interactions and physiological processes in marine algae and seagrass. among others, dasycladus vermicularis (scopoli) krasser 1898 uses a sulfated hydroxylated coumarin derivative as storage metabolite for a protein cross linker that can be activated upon mechanical disruption of the alga. we introduce a comprehensive monitoring technique for sulfated metabolites based on fragmentation patterns in liquid chromatography/mass sp ...201526188914
sulfation mediates activity of zosteric acid against biofilm formation.zosteric acid (za), a metabolite from the marine sea grass zostera marina, has attracted much attention due to its attributed antifouling (af) activity. however, recent results on dynamic transformations of aromatic sulfates in marine phototrophic organisms suggest potential enzymatic desulfation of metabolites like za. the activity of za was thus re-investigated using biofilm assays and simultaneous analytical monitoring by liquid chromatography/mass spectrometry (lc/ms). comparison of za and i ...201525915112
the case for the proposed increase in iron enrichment of flour and wheat products. 20155023246
the kidney in sickle cell disease ii: the kidney and sickling phenomenon. 20164805648
construction of a bioreporter by heterogeneously expressing a vibrio natriegens reca::luxcdabe fusion in escherichia coli, and genotoxicity assessments of petrochemical-contaminated groundwater in northern china.here, we constructed an escherichia coli reca::luxcdabe bioreporter for genotoxicity assessments. the reca promoter was cloned from the marine bacterium vibrio natriegens. this bioreporter showed a dose-response relationship following induction by mitomycin c, and other pollutants or environmental samples could be calculated as mitomycin c equivalents, which provided a way to quantitatively compare the genotoxicities of different environmental samples. this bioreporter was used to evaluate the g ...201627258332
vibrio natriegens as a fast-growing host for molecular biology.a rapidly growing bacterial host would be desirable for a range of routine applications in molecular biology and biotechnology. the bacterium vibrio natriegens has the fastest growth rate of any known organism, with a reported doubling time of <10 min. we report the development of genetic tools and methods to engineer v. natriegens and demonstrate the advantages of using these engineered strains in common biotech processes.201627571549
pseudosarcoma of the skin. an electron microscopic study and comparison with the fine structure of spindle-cell variant of squamous carcinoma. 20164819223
multiplex genome editing by natural transformation (mugent) for synthetic biology in vibrio natriegens.vibrio natriegens has recently emerged as an alternative to escherichia coli for molecular biology and biotechnology, but low-efficiency genetic tools hamper its development. here, we uncover how to induce natural competence in v. natriegens and describe methods for multiplex genome editing by natural transformation (mugent). mugent promotes integration of multiple genome edits at high-efficiency on unprecedented time scales. also, this method allows for generating highly complex mutant populati ...201728571309
environmental impact of tributyltin-resistant marine bacteria in the indigenous microbial population of tributyltin-polluted surface sediments.we compared the tbt-resistant ability of resting cells prepared from isolates that formed colonies on nutrient agar plates containing 100 µm tributyltin (tbt) chloride, such as photobacterium sp. tky1, halomonas sp. tky2, and photobacterium sp. ngy1, with those from taxonomically similar type strains. photobacterium sp. tky1 showed the highest ability among those three isolates. the number of surviving photobacterium sp. tky1 cells was hardly decreased after 1 h of exposure to 100 µm tbtcl, rega ...201728659560
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