Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| effect of antihypertensive drugs on insulin, glucose, and lipid metabolism. | the close relationship between diabetes and hypertension has been recognized for decades. new information indicates that resistance to insulin action on glucose uptake in peripheral tissues is a common underlying mechanism in hypertension and diabetes. in prospective trials, the effects of antihypertensive agents on insulin sensitivity and lipoprotein metabolism have been evaluated. both beta-blockers and thiazide diuretics worsen insulin resistance and deteriorate lipoprotein metabolism. angiot ... | 2006 | 1828417 |
| effect of antihypertensive drugs on insulin, glucose, and lipid metabolism. | the close relationship between diabetes and hypertension has been recognized for decades. new information indicates that resistance to insulin action on glucose uptake in peripheral tissues is a common underlying mechanism in hypertension and diabetes. in prospective trials, the effects of antihypertensive agents on insulin sensitivity and lipoprotein metabolism have been evaluated. both beta-blockers and thiazide diuretics worsen insulin resistance and deteriorate lipoprotein metabolism. angiot ... | 2006 | 1828417 |
| structure of the rabbit phospholamban gene, cloning of the human cdna, and assignment of the gene to human chromosome 6. | we have isolated and characterized genomic dna clones encoding rabbit phospholamban. only a single gene for phospholamban was detected in the rabbit genome. the phospholamban gene of 13.2 kilobases contains only one 10.5-kilobase intron, which separates exonic sequences located in the 5'-untranslated region. two potential transcription initiation sites were mapped to 335 and 185 nucleotides upstream from the translation initiation site in the mrna or 239 and 89 nucleotides upstream from the exon ... | 1991 | 1828805 |
| [atypical and combined forms of infectious-allergic polyneuropathies]. | 2007 | 1865642 | |
| intracerebral hemorrhage, cerebral infarction, and subdural hematoma after acute myocardial infarction and thrombolytic therapy in the thrombolysis in myocardial infarction study. thrombolysis in myocardial infarction, phase ii, pilot and clinical trial. | in the thrombolysis in myocardial infarction, phase ii pilot and clinical trial, 908 patients [326 (35.9%) in the pilot study and 582 (64.0%) in the randomized study] were treated with 150 mg recombinant tissue-type plasminogen (rt-pa) activator in combination with heparin and aspirin, and 3,016 patients [64 (2.1%) in the pilot study and 2,952 (97.9%) in the randomized study] were treated with 100 mg rt-pa in combination with heparin and aspirin. adverse neurological events occurred in 23 patien ... | 2007 | 1899364 |
| expression of antifreeze proteins in transgenic plants. | the quality of frozen fruits and vegetables can be compromised by the damaging effects of ice crystal growth within the frozen tissue. antifreeze proteins in the blood of some polar fishes have been shown to inhibit ice recrystallization at low concentrations. in order to determine whether expression of genes of this type confers improved freezing properties to plant tissue, we have produced transgenic tobacco and tomato plants which express genes encoding antifreeze proteins. the afa3 antifreez ... | 1991 | 1932678 |
| purification and characterization of a heat-stable enterotoxin of vibrio mimicus. | a heat-stable enterotoxin produced by vibrio mimicus (vm-st) was studied. vm-st was purified from a culture supernatant of v. mimicus strain aq-0915 by ammonium sulfate fractionation, hydroxyapatite treatment, ethanol extraction, column chromatography on both sp-sephadex c-50 and deae-sephadex a-25, and hplc, and the recovery rate was about 15%. purified vm-st was heat-stable. vm-st activity was cross-neutralized by anti-sth antiserum. the amino acid composition of the purified vm-st was determi ... | 1991 | 2044934 |
| [surveys on the contamination of marine fish with non-o1 vibrio cholerae and vibrio mimicus and food poisoning cases by these organisms]. | the present paper describes the relationship between the contamination with non-o1 vibrio cholerae and vibrio mimicus of marine fish, with special reference to the seasonal variation and the concentration of contamination, and the actual cases of domestic food poisoning by these organisms. a 10 year survey revealed that non-o1 vibrio cholerae (non-o1 v. cholerae) strains were frequently isolated from fish during the summer season with some variations from one year to another, and isolates from f ... | 1991 | 2066602 |
| a vasopressin and oxytocin containing nucleus in the pig hypothalamus that shows neuronal changes during puberty. | a vasopressin and oxytocin containing nucleus is described for the first time in the pig hypothalamus. it is located near the third ventricle, just dorsal to the suprachiasmatic nucleus, and consists of magnocellular neurons, similar to those of the supraoptic nucleus and paraventricular nucleus. morphometric analysis of neuronal number, size, density, and volume was performed at four different ages: 1 day, 7 weeks, 16 weeks, and 30 weeks postnatally. no sex difference in these parameters was ob ... | 1990 | 2077051 |
| subunit analysis of bovine cytochrome c oxidase by reverse phase high performance liquid chromatography. | bovine cytochrome c oxidase subunits were separated by reverse phase high performance liquid chromatography using a c4 column eluted with water and an acetonitrile gradient, both containing 0.1% trifluoroacetic acid. subunits i and iii precipitated in this solvent and could not be analyzed; the remaining eleven subunits were dissociated, denatured, soluble and could be resolved by elution from the column. the protein subunit eluting in each chromatographic peak was identified by a combination of ... | 1990 | 2168156 |
| purification and characterization of a protease produced by vibrio mimicus. | a protease produced by vibrio mimicus was purified to apparent homogeneity by ammonium sulfate fractionation and successive column chromatography on sephacryl s-100 and mono q monobeads. the sodium dodecyl sulfate-polyacrylamide gel electrophoresis (page) of the final preparation of the enzyme revealed the homogeneity of the purified enzyme. conventional page showed that the purified protease migrated as a single band with protease activity. the molecular weight of the protease was estimated to ... | 1990 | 2254038 |
| nucleotide sequence of the thermostable direct hemolysin gene (tdh gene) of vibrio mimicus and its evolutionary relationship with the tdh genes of vibrio parahaemolyticus. | the gene encoding a hemolysin similar to the thermostable direct hemolysin (tdh) of vibrio parahaemolyticus was previously cloned from the chromosome of vibrio mimicus. the nucleotide sequence of the hemolysin gene was determined in this study. the gene proved to be a variant of the thermostable direct hemolysin gene (tdh gene) and was designated as vm-tdh because the sequence divergences between the vm-tdh gene and four tdh genes of v. parahaemolyticus were 2.1-3.0%, while the sequence divergen ... | 1990 | 2272498 |
| generation of affinity for antithrombin iii by supplemental sulfation of heparin species with low affinity for the protein. | the tributylammonium salt of a porcine heparin subfraction with low affinity for antithrombin iii (mr 7,500-18,000; anti-clotting activity, 7 usp units/mg), having degrees of sulfate substitution at d-glucosamine and l-iduronic acid residues of glcns 0.786, glcn6s 0.628, and idoa2s 0.682 mol, was reacted with 10 or 20 mol of pyridine-sulfur trioxide per mol equiv. of available hydroxyl groups in n,n-dimethylformamide at -10 degrees c for 1 h. both chemical and nmr spectroscopic analyses revealed ... | 1990 | 2292586 |
| identification and characterization of the nmyc gene product in human neuroblastoma cells by monoclonal antibodies with defined specificities. | increased n-myc (now designated nmyc in human gene nomenclature) gene expression has been detected at the transcriptional level in certain types of neoplasms. as yet, the n-myc gene product has not been identified. to detect and characterize the n-myc gene product, we have developed monoclonal antibodies against the putative n-myc gene product made in escherichia coli as a fusion protein. the antibodies that recognize the n-myc-specific regions were selected on the basis of their reactivities to ... | 1986 | 2426708 |
| sugar composition of the polysaccharide portion of lipopolysaccharides of vibrio fluvialis, vibrio vulnificus, and vibrio mimicus. | a chemotaxonomic study was carried out on vibrio fluvialis and v. vulnificus on the basis of the sugar composition of the polysaccharide portion of their lipopolysaccharides (lps). a previously developed rapid method of preparing samples for compositional sugar analysis was employed. nineteen o-serogroups of v. fluvialis were divided into 14 chemotypes while seven o-serogroups of v. vulnifucus were divided also into seven chemotypes since the polysaccharide portion of lps of each serogroup has a ... | 1989 | 2482433 |
| [isolation of vibrio mimicus from shallow waters]. | 1989 | 2490717 | |
| isolation of vibrio mimicus from a patient with gastroenteritis in belgium. | 1989 | 2495957 | |
| stress-induced behavioral depression in the rat is associated with a decrease in gaba receptor-mediated chloride ion flux and brain benzodiazepine receptor occupancy. | rats exposed to inescapable tailshock exhibit deficits in learning a simple shuttlebox escape task 24 h later. this syndrome has been termed 'behavioral depression' or 'learned helplessness', and is a model of stress-induced depression. in the present study a significant (25%) decrease in gaba receptor-mediated chloride ion flux as measured by muscimol-stimulated 36cl- uptake in synaptoneurosomes was found in the cerebral cortices of rats that failed the shuttlebox task as compared to naive cont ... | 1989 | 2546650 |
| a randomized trial of anticoagulation with warfarin and of alternating chemotherapy in extensive small-cell lung cancer by the cancer and leukemia group b. | the cancer and leukemia group b (calgb) conducted a prospective randomized trial to evaluate the role of warfarin and alternating chemotherapy in extensive small-cell lung cancer (sccl). after stratification for sex and performance status, patients were randomly assigned to receive chemotherapy with methotrexate, doxorubicin (adriamycin; adria laboratories, columbus, oh), cyclophosphamide, and lomustine (ccnu) (macc), or macc plus warfarin (macc + w), or mitomycin, etoposide, cisplatin, and hexa ... | 2008 | 2547030 |
| distortion product emissions and sensorineural hearing loss. | distortion product emissions (dpes) are intimately linked to normal outer hair cell function. outer hair cell function is itself intimately linked with normal auditory thresholds. we sought to correlate frequency-specific dpe measurements with auditory thresholds, in seven frequency regions from 700 hz to 6 khz, in each of 21 ears. eleven of these ears had thresholds below 25 db spl at every test frequency, whereas 10 ears demonstrated some degree of purely sensorineural hearing loss. an analysi ... | 2008 | 2593222 |
| development and degeneration of retina in rds mutant mice: altered disc shedding pattern in the heterozygotes and its relation to ocular pigmentation. | in the heterozygous mutant (rds/+) mice, receptor outer segments (ros) are irregular in form and are shed as abnormally large phagosomes. in the albino rds/+ mice, peak frequency of pigment epithelial (rpe) phagosomes is higher than normal and is recorded near the end of the light period, instead of at the time of light onset as in the normal (+/+) albino mice. in pigmented mice of both genotypes, the maximum numbers of phagosomes in the rpe remain lower than in the albinos. in pigmented +/+ mic ... | 2009 | 2612198 |
| amoxicillin in the treatment of asymptomatic bacteriuria in pregnancy: a single dose of 3 g amoxicillin versus a 4-day course of 3 doses 750 mg amoxicillin. | a prospective, randomized, controlled comparative clinical trial was carried out with the aim of investigating the efficacy and tolerance of two different dosage regimens of amoxicillin in the treatment of asymptomatic bacteriuria during pregnancy. patients in group a received a single dose of 3 g amoxicillin, which was compared to a 4-day course of 3 x 750 mg amoxicillin tablets taken every 8 h (group b). significant bacteriuria (cfu greater than or equal to 10(5)/ml clean catch midstream urine ... | 1989 | 2659442 |
| [poisoning by geromitra esculenta]. | gyromitra esculenta (persoon ex fries) mushrooms have been responsible for severe intoxications and even deaths. clinical data are characterized primarily by vomiting and diarrhoea, and, afterwhile, by jaundice, convulsions and coma. the species of concern are mainly g. esculenta, g. fastigiata and g. gigas; nevertheless, recent advances in chromatography, biochemistry and toxicology have established that other species within the ascomycetes may prove also toxic. the toxins, i.e. gyromitrin (n-m ... | 2009 | 2681713 |
| [70 years nursing school innsbruck]. | 2009 | 2694061 | |
| evaluating the optometric literature: the educated clinician. | the purpose of this article is to present a framework for reader evaluation of optometric literature. the elements of a research article are outlined. suggestions are presented that clinicians can use to develop competence in evaluating research literature. also presented is an annotated bibliography of research references. better patient care and increased professional growth will result when clinicians evaluate and make use of the research literature. | 2008 | 2703662 |
| evaluating the optometric literature: the educated clinician. | the purpose of this article is to present a framework for reader evaluation of optometric literature. the elements of a research article are outlined. suggestions are presented that clinicians can use to develop competence in evaluating research literature. also presented is an annotated bibliography of research references. better patient care and increased professional growth will result when clinicians evaluate and make use of the research literature. | 2008 | 2703662 |
| heterogeneity of fast-oxidative muscle fibers of chicken demonstrated by anti-myosin monoclonal antibodies. | the fiber type composition of two fast muscles of the chicken, namely, adductor superficialis (as) and pectoralis major (pm) was examined by the histochemical myosin atpase staining and immunochemical techniques using monoclonal antibodies (mcabs). two new mcabs produced against the myosin of the anterior latissimus dorsi (ald) muscle of the chicken and named ald-122 and ald-83 were characterized to be specific for myosin heavy chain (mhc) and for myosin light chain-1 respectively. they were use ... | 1989 | 2737924 |
| anomalous origin of right pulmonary artery from the ascending aorta. | anomalous origin of one pulmonary artery from the ascending aorta without associated intracardiac defects is a rare congenital malformation. about 60 anatomic and surgical descriptions have been reported in the literature. up to 1974, 22 of the 50 reported cases underwent surgical correction with a 40% mortality rate. the natural history without surgery is poor with a very high mortality during the first year of life. successful anatomic correction of anomalous origin of right pulmonary artery f ... | 2009 | 2777879 |
| ecology of vibrio mimicus in aquatic environments. | an environmental study was done to examine the prevalence of vibrio mimicus in some aquatic environments of dhaka, bangladesh, and of okayama, japan. water samples from dhaka environments and water and plankton samples from okayama environments were quantitatively as well as qualitatively analyzed throughout the seasons for v. mimicus. the organism was isolated from bangladesh environments throughout the year, whereas it was not isolated in okayama when the water temperature fell below 10 degree ... | 1989 | 2782878 |
| [the results of an investigation of the various factors influencing the late patency ratio of coronary bypass grafting]. | the purpose of this communication was to find out the factors influencing the late patency ratio of coronary artery bypass grafts of 42 patients in our institution. the following results were obtained: 1. the size of the measured diameters of coronary arteries and the graft flow rates were correlated well to the late patency ratio (p less than 0.05). 2. the regular physical exercise trainings were significantly important to keep patent grafts (p less than 0.01). 3. in blood serum studies, serum ... | 2009 | 2786538 |
| [epidemiologic investigations on caries prevalence among schoolchildren in brittany (france)]. | 1421 randomly selected 6- to 15-year-old breton children were examined in 1987 in order to assess the prevalence of caries in permanent teeth. methods proposed by turlot & cahen (1989) were used. at 6, 85.9% of all children were caries-free and at 15, only 5.3%. at 14, dmft and dmfs rates reached 6.46 and 12.36, respectively. the differences of scores stated between boys and girls and between children from urban and rural regions were not statistically significant. pits and fissures were more fr ... | 2010 | 2799351 |
| more on index of refraction. | 2009 | 2805311 | |
| more on index of refraction. | 2009 | 2805311 | |
| effects of blocked versus random practice by mentally retarded subjects on learning a novel skill. | the purpose of this study was to assess the effects of different practice conditions on mentally retarded subjects learning a novel task. 20 subjects with a mean iq of 51.82 were randomly assigned to one of two practice conditions. the first group practiced at three different speeds (60, 30, and 15 rpm) on the pursuit rotor using a block arrangement in which each speed was practiced for five consecutive trials of 20 sec. duration before practicing at the next speed. the second group used random ... | 2010 | 2812988 |
| mechanism of the epsp synthase catalyzed reaction: evidence for the lack of a covalent carboxyvinyl intermediate in catalysis. | in order to detect covalent reaction intermediates in the 5-enolpyruvylshikimate-3-phosphate (epsp) synthase reaction, we have investigated the interaction of epsp synthase with the reaction product epsp. an exchange of epsp-methylene protons could be demonstrated by incubating epsps with epsp in d2o. since trace amounts of contaminating pi would lead to reversal of epsps reaction and hence methylene proton exchange, we added pyruvate kinase, adp, mg++ and k+. under these conditions, any contami ... | 1988 | 2838023 |
| [biochemical aspect in cardiac ischemia--ischemic changes and reperfusion injury]. | 2010 | 2838873 | |
| anticholinergic drugs in the treatment of airways disease. | 2010 | 2861843 | |
| evidence of functional alpha 2-adrenergic receptors in adult-rat adipocytes by using the agonist uk 14304. | the aim of this study was to re-assess whether alpha 2-adrenergic receptors were present in rat adipocytes, by using uk 14304, a new and very selective alpha 2-agonist. the following observations demonstrate the presence of functional alpha 2-adrenoceptors in rat adipocytes. (1) adipocyte lipolysis was dose-dependently inhibited by uk 14304 (maximal effect 80% at 1 microm-uk 14304, 45% at 10 microm-uk 14304, under basal or theophylline-stimulated conditions respectively). (2) uk 14304 bound spec ... | 1988 | 2901830 |
| the biologic significance of the mixed lymphocyte kidney culture in humans. | the mixed lymphocyte kidney culture (mlkc) in humans has been studied in normal and abnormal clinical conditions. human renal cortical cells were extracted by collagenase treatment from the kidneys of "normal" heart-beating cadaver organ donors (n = 13), patients with end-stage renal disease (esrd) at pretransplant bilateral nephrectomy and splenectomy (n = 13), and from irreversibly rejected renal allografts at the time of graft nephrectomy (n = 5). proliferation of peripheral blood t lymphocyt ... | 1985 | 2996186 |
| effect of pyrimidinone treatment on lethal and immunosuppressive murine cytomegalovirus infection. | the 2-amino-5-halo-pyrimidinones, which are potent interferon inducers and antiviral agents, were found to be protective against lethal cytomegalovirus (cmv) challenge in weanling or neonatal mice when administered before virus challenge. this protection was dependent upon the dosage of pyrimidinone administered. weanling mice infected with a sublethal challenge of cmv exhibited moderate to severe immunosuppression as measured by reduced splenic cell blastogenic responses in vitro to the mitogen ... | 1985 | 3000290 |
| molecular epidemiology of non-o1 vibrio cholerae and vibrio mimicus in the u.s. gulf coast region. | ten toxigenic vibrio cholerae non-o1 and v. mimicus strains isolated from clinical and environmental sources in the u.s. gulf coast region were examined for genetic relatedness. restriction digest patterns of chromosomal dna and southern blot analysis with a cholera toxin gene probe revealed that the strains exhibited greater genetic divergence than the highly conserved v. cholerae o1 strains isolated from clinical and sewage samples in this region. | 1986 | 3007571 |
| evidence that a human soluble beta-galactoside-binding lectin is encoded by a family of genes. | two cdna clones were isolated by immunoscreening a human hepatoma cdna library with an antiserum that bound specifically to a human soluble beta-galactoside-binding lectin with mr of approximately 14,000. the deduced amino acid sequences of the inserts of these two clones show considerable homology with each other, the sequence of chicken skin beta-galactoside-binding lectin, and eight peptides derived from purified human lung lectin of mr approximately 14,000. however, the sequence differences ... | 1986 | 3020551 |
| evidence that a human soluble beta-galactoside-binding lectin is encoded by a family of genes. | two cdna clones were isolated by immunoscreening a human hepatoma cdna library with an antiserum that bound specifically to a human soluble beta-galactoside-binding lectin with mr of approximately 14,000. the deduced amino acid sequences of the inserts of these two clones show considerable homology with each other, the sequence of chicken skin beta-galactoside-binding lectin, and eight peptides derived from purified human lung lectin of mr approximately 14,000. however, the sequence differences ... | 1986 | 3020551 |
| gene expression and genetic engineering in the lens. friedenwald lecture. | 1987 | 3026987 | |
| role of postnatal gonadal function in the determination of thyrotropin (tsh) releasing hormone-induced tsh response in adult male and female rats. | permanent effects of postnatal gonadal function on the hypothalamo-pituitary-thyroid axis were examined in male and female rats of the wistar-imamichi strain. animals were used at the age of about 10 weeks. neonatally castrated (nc) males showed a significantly higher plasma tsh response to trh (10 micrograms/kg bw, ip) than males castrated at 1, 2, 3, 4, or 6 weeks of age. the tsh response in intact males was similar to that seen in nc males. neonatal androgenization of nc males with 100 microg ... | 1987 | 3032567 |
| the hypothalamic-pituitary-adrenal axis in depression. | 2010 | 3035885 | |
| [x-ray computed tomography in venous pathology]. | after presenting the tomodensitometric semiology of venous thromboses in various territories, the authors define its indications. it is essentially in deep territories, head, chest and abdomen that the ct-scan is used to study and diagnose unrecognized thromboses as well as determine the venous repercussion of various neighboring ailments. the respective place of the ct-scan, ultrasonography and various phlebographies is analyzed. | 2011 | 3043474 |
| second-generation cephalosporins. | 1986 | 3081544 | |
| annual summary 1984. reported morbidity and mortality in the united states. | 2011 | 3092006 | |
| biosynthesis and processing of platelet gpiib-iiia in human megakaryocytes. | platelet membrane glycoprotein iib-iiia forms a calcium-dependent heterodimer and constitutes the fibrinogen receptor on stimulated platelets. gpiib is a two-chain protein containing disulfide-linked alpha and beta subunits. gpiiia is a single chain protein. these proteins are synthesized in the bone marrow by megakaryocytes, but the study of their synthesis has been hampered by the difficulty in obtaining enriched population of megakaryocytes in large numbers. to examine the biosynthesis and pr ... | 1987 | 3108266 |
| darkroom diseases and how to combat them. | 2011 | 3112384 | |
| oesophageal pain exacerbated by propranolol. | 2011 | 3113570 | |
| increased cough reflex associated with angiotensin converting enzyme inhibitor cough. | 2011 | 3120857 | |
| [enterostoma therapy--a pilot course in the essen education center of the german nursing association]. | 2011 | 3127632 | |
| valproate-associated hepatotoxicity and its biochemical mechanisms. | intake of the anticonvulsant drug valproic acid, or its sodium salt, has been associated with occasional instances of severe and sometimes fatal hepatotoxicity. probably at least 80 cases have occurred worldwide. the syndrome affects perhaps 1 in 10,000 persons taking the drug, and usually develops in the early weeks or months of therapy. most instances have involved children, usually those receiving more than 1 anticonvulsant. multiple cases have occurred in 2 families. the typical presentation ... | 2011 | 3131628 |
| renal growth after neonatal urinary tract infection. | this study presents the result of 12-21 years' follow-up in a group of children with neonatal urinary tract infection (onset within 1 month after birth) in whom early renal growth retardation was noted without concomitant classical renal scarring. in all cases the neonatal infection was diagnosed and treated within a few days of onset and the patients were closely supervised thereafter. renal length, parenchymal thickness and area were measured at urography. at first follow-up (22 children, mean ... | 2010 | 3153287 |
| direct selection of mutations reducing transcription or translation of the reca gene of escherichia coli with a reca-lacz protein fusion. | when a reca-lacz protein fusion was cloned into phage lambda, the resulting transducing phage grew normally on wild-type escherichia coli, but its growth was severely inhibited in lexa(def) mutant strains that express reca constitutively at high levels. mutants of the transducing phage that grew on the lexa(def) strains were isolated and were found to affect production of the reca-beta-galactosidase hybrid protein. most mutants, including a number of nonsense mutants, were phenotypically lacz-. ... | 1985 | 3160689 |
| structural and functional studies of the effects of sympathetic nerve stimulation on rabbit submandibular salivary glands. | continuous sympathetic stimulation at 8-10 hz caused intense vasoconstriction in the gland, so stimulation was generally given in an interrupted pattern to minimize this detrimental effect on secretion. only a small increase in fluid secretion occurred; it became thick and tended to block the cannula; therefore in later experiments the main duct was not cannulated. after sympathetic stimulation there was substantial degranulation of acinar cells. however, as this was accompanied by little moveme ... | 1988 | 3165262 |
| coagglutination of vibrio cholerae, vibrio mimicus, and vibrio vulnificus with anti-flagellar monoclonal antibody. | monoclonal antibodies (mabs) with serological activity for purified flagellar (h) core protein prepared from vibrio cholerae were identified by enzyme-linked immunosorbent assay. four of these mabs reacted with the flagella of v. cholerae and v. mimicus exclusively, while eight mabs reacted with at least 1 of 30 heterologous vibrio species tested by enzyme-linked immunosorbent assay or coagglutination. it appears that v. cholerae and v. mimicus express similar, if not identical, h determinants u ... | 1988 | 3182988 |
| studies on the factors affecting the haemolysin production of vibrio mimicus isolated from clinical and environmental sources. | the in vitro production of haemolysin by vibrio mimicus, a newly described aetiological agent for human diarrhoea, was determined using sheep erythrocytes. the effects of medium composition and sodium chloride concentration on haemolysin production and its heat stability were investigated. the haemolysin was produced optimally in brain-heart infusion broth and was unaffected by salt concentration up to 1.5%. however, haemolysin production decreased gradually with increasing concentrations of sal ... | 1988 | 3188168 |
| physical and psychological sequelae to torture. a controlled clinical study of exiled asylum applicants. | the study comprised 24 male lebanese refugees living in denmark. twelve of them alleged having been tortured in lebanon during the period 1981-85. the remaining twelve had neither been imprisoned nor tortured and thus acted as control persons. all the testimonies were found to be valid according to a method previously used by the author. the most common forms of torture were blows against the head, body and foot soles, suspension and asphyxiation. threats and solitary confinement were frequent, ... | 2011 | 3209147 |
| excision of cutaneous tumors in the horse using histologic guidance. | a highly successful surgical technique for removing cutaneous tumors in humans was used in seven horses with cutaneous squamous cell carcinoma (n = 3) or sarcoid (n = 4). in humans, the complete underside of the tumor is evaluated histologically by processing horizontal sections from the tumor base, and orientation between the wound surface and the undersurface of the excised tumor is maintained by mapping both surfaces. the technique ensures that small foci of residual tumor can be located accu ... | 1988 | 3227634 |
| computer-aided molecular modelling: research study or research tool? | developments in computational methods and equipment have produced a new type of research chemist, who prefers to calculate properties as well as measure them, either to gain a better understanding of microscopic molecular behaviour per se, or to guide a broader scientific study using a so-called 'rational' approach. while there is good reason to believe that significant results can be obtained this way, it is clear that only some of the 'tools of the trade' are sufficiently robust to present to ... | 2011 | 3236047 |
| synthesis and antineoplastic effects of furo[3,4-d]pyrimidine derivatives. | furo[3,4-d]pyrimidine was obtained in the reaction of 2-phenyl-4-phenylamino-6-methyl-5-pyrimidinecarboxylic acid with socl2. this compound, heated with aliphatic amines, yielded mono- and diamino-derivatives. some of the obtained compounds exhibited a potent antineoplastic activity. | 2011 | 3237569 |
| hypergammaglobulinemia associated with human immunodeficiency virus infection. | the serum concentrations of 11 ig isotypes (igg, igg1, igg2, igg3, igg4, iga, iga1, iga2, igm, igd, and ige) were measured in four relatively small groups of homosexual (or bisexual) males. all these patients were seropositive for hiv. two of the groups (nonprogressors) were clinically stable for approximately 2 years and were characterized either as asymptomatic or with pgl. the third group (progressors) developed aids 2-38 months after blood specimens were taken. the fourth group had aids. a f ... | 1988 | 3260340 |
| [respiratory problems in patients with muscular dystrophy]. | 2011 | 3285556 | |
| structural and functional studies of the amino terminus of yeast metallothionein. | purified yeast copper-metallothionein lacks 8 amino-terminal residues that are predicted from the dna sequence of its gene. the removed sequence is unusual for metallothionein in its high content of hydrophobic and aromatic residues and its similarity to mitochondrial leader sequences. to study the significance of this amino-terminal cleavage, several mutations were introduced into the metallothionein coding gene, cup1. one mutant, which deletes amino acid residues 2-8, had a minor effect on the ... | 1987 | 3308865 |
| simultaneous measurement of preferred ambient temperature and metabolism in rats. | a recent study from this laboratory found that rats placed in a temperature gradient preferred ambient temperatures (ta) that were significantly below the lower critical ta of the thermoneutral zone for elevating metabolic rate (mr). to further evaluate the interaction between preferred ta and mr in the rat, a system was developed where preferred ta, mr (i.e., o2 consumption), and activity could be automatically monitored in the unrestrained rat. two groups of male sprague-dawley rats, a light-w ... | 1988 | 3344833 |
| effects of adult and peer social initiations on the social behavior of withdrawn, maltreated preschool children. | 2012 | 3346446 | |
| smooth muscle tumours of the digestive tract: report of 160 cases. | of 160 patients seen in the period 1951-84 with smooth muscle tumours of the digestive tract, 71 proved to have leiomyomas, 87 had leiomyosarcomas and 2 had leiomyoblastomas. tumour diameter was frequently greater in patients with leiomyosarcoma. the surgical mortality was 2.8 per cent after treatment of leiomyoma and 10.3 per cent after treatment of leiomyosarcoma. after resection of leiomyosarcoma the 2-year survival rate was 86 per cent and the 5-year survival rate was 43 per cent. the only h ... | 2012 | 3349313 |
| [ambulatory observation of patients with neuritis of the optic nerve]. | 2012 | 3387000 | |
| thyroglobulin and 131i uptake of remaining tissue in patients with differentiated carcinoma after thyroidectomy. | in 158 thyroidectomized patients with well-differentiated non-metastatic thyroid cancer the results of serum thyroglobulin (tg) determination and 131i uptake values established immediately before radioiodine treatment (19 days after surgery) were compared. in 113 patients (72%) tg was above 6 ng ml-1 (lower limit of detection) and 131i uptake exceeded 2%. in 11 patients (7%) tg was undetectable and 131i uptake less than 2%. in these cases a radioiodine treatment was not performed; the thyroid ab ... | 2012 | 3399222 |
| natural cooling of the brain during outdoor bicycling? | tympanic membrane temperature (ttymp) and deep esophageal temperature (tes) were measured in 8 subjects during normal outdoor bicycling. metabolic rate (vo2) was determined by the douglas bag method. heart rate was sampled continuously. skin surface temperatures were measured at the forehead, chest and shoulder, and core temperatures in the deep esophagus and at the tympanic membrane using a radio telemetry system. for each outdoor experiment an indoor experiment in a climatic chamber, adjusted ... | 2012 | 3399365 |
| a pedigree of leber's congenital amaurosis. | a pedigree of leber's congenital amaurosis compatible with autosomal recessive trait is reported. two male infants from consanguineous parents had remarkable visual loss within the first year of life, with sluggish pupillary responses, poor fixations, minimal eyeground changes and absent electroretinograms on presentations at the ages of four or 14 months. follow-up studies revealed definite progressions of eyeground abnormalities consisting of attenuated retinal arterioles, pepper- and salt-lik ... | 2012 | 3405591 |
| commonly adopted postures and their effect on the lumbar spine. | the activity of the erector spinae muscles and the changes in lumbar curvature were measured in 11 subjects in a range of commonly adopted postures to see if there were any consistent trends. surface electrodes were used to measure back muscle activity and lumbar curvature was measured using electronic inclinometers. the results showed that many commonly adopted postures reduced the lumbar lordosis when compared with erect standing or sitting, even at the expense of increasing the back muscle ac ... | 2012 | 3406840 |
| reverse genetics approaches for cloning ril-1, a major locus involved in susceptibility to leukemia. | 2012 | 3416638 | |
| agoraphobia and parental bereavement. | the prevalence of parental bereavement was determined in 50 married female outpatients with a dsm-iii diagnosis of agoraphobia and in a control group of married female outpatients diagnosed as having non-psychotic psychiatric disorders other than agoraphobia. the two groups were matched for age and overall severity of psychiatric symptoms. compared with the general population, the patient control group reported a statistically significant excess of parental, but not maternal, bereavement. the ag ... | 2012 | 3435374 |
| [studies on the blood constituents of the neonates delivered by the induced delivery of the defense medical college method]. | for the assessment of the influence of the defense medical college planned delivery method upon neonates, the measurement of the blood constituents of the umbilical cord was conducted. statistically speaking, no marked differences were seen between the neonates delivered by the defense medical college method and neonates delivered naturally. the blood constituents investigated were: blood cells, activity of various enzymes, other blood constituents and electrolytes. | 2012 | 3457089 |
| trimethoprim used for selective decontamination of the digestive tract in rats: possible route of excretion. | selective elimination of enterobacteriaceae species from the digestive tract of rats has been accomplished by oral treatment with trimethoprim (235 mg/kg body weight/day) within 6 days. in the present study it was investigated whether this elimination was mainly due to antimicrobial activity of trimethoprim excreted with the gastrointestinal mucus or mainly by non-absorbed trimethoprim in the lumen contents. by means of whole gut irrigation (wgi) the lumen contents were washed out, followed by m ... | 1987 | 3497436 |
| evaluation of aerosolized triamcinolone acetonide as a replacement for aerosolized beclomethasone dipropionate. | substitution of aerosolized triamcinolone acetonide for aerosolized beclomethasone dipropionate in treatment of 30 chronic asthmatics resulted in subjective improvement in all patients. there was reduction in requirement of systemic steroids and inhaled beta adrenergics. no adrenal suppression or oropharyngeal candidiasis occurred after replacing beclomethasone dipropionate with triamcinolone acetonide. | 2012 | 3528120 |
| effect of motion on the sonographic and magnetic resonance patterns of ageing blood. | the sonographic appearance of a hematoma may be affected by various factors, including the age of the hematoma. the effect of mechanical motion on the echogenicity and histologic appearance, and on the proton relaxation times t1 and t2 of blood clots, was studied in vitro for up to 21 days. all clots were of similar echogenicity and microscopic appearance during the first 2 days. the minimally disturbed clots were sonolucent from day 4 onwards, whereas moderate mechanical disturbance changed the ... | 1986 | 3535388 |
| nocardia asteroides as a cause of corneal ulcer. case report. | 1987 | 3551895 | |
| the morphology and distribution of serotonin-like immunoreactive fibers in the cat dorsal column nuclei. | fibers showing serotonin-like immunoreactivity (5-ht-li) are demonstrated in the gracile, cuneate and external cuneate nuclei of the cat using avidin-biotinylated horseradish peroxidase and indirect fluorescence immunohistochemical methods. 5-ht-li fibers are located in all cytoarchitectural subdivisions of the gracile and cuneate nuclei but are restricted to the medial half of the external cuneate nucleus. in all nuclei, 5-ht-li fibers consist of long, varicose strands showing a wide range in t ... | 1987 | 3554006 |
| anticoccidial activity of alborixin. | alborixin, a polyether antibiotic with ionophore properties, was evaluated to determine the effect of the drug on weight gain of chickens and to define the anticoccidial spectrum of activity. the 50-ppm concentration in the diet was identified as the maximum level that did not significantly reduce weight gain beyond that of monensin (standard drug); consequently, the drug was evaluated for anticoccidial activity at this dilution. at the 50-ppm level, alborixin demonstrated broad-spectrum anticoc ... | 1987 | 3572663 |
| emergency room thoracotomy for stab wounds to the chest and neck. | this study group comprises 73 patients who underwent emergency room resuscitative thoracotomy for cardiac arrest following penetrating chest and neck injuries. overall, 12 patients (16.4%) were successfully resuscitated but only five (6.8%) left the hospital alive without neurologic defects. none of the 18 cases with no vital signs at all (no cardiac activity, no respiratory efforts, nonreactive pupils) on admission survived. only one out of the 19 cases with no cardiac activity and with fixed p ... | 2013 | 3573102 |
| recommendations for research in the epidemiology of asthma. | 2013 | 3581962 | |
| incidence of vibrio cholerae from estuaries of the united states west coast. | the incidence of vibrio cholerae in shellfish, sediment, and waters of california, oregon, and washington was determined during the summer of 1984. samples from 24 distinct estuaries were analyzed qualitatively. v. cholerae non-o1 was found in 23 estuaries and in 44.6% of the 529 samples examined. v. cholerae o1 inaba was isolated from water samples in morro bay, calif. vibrio mimicus was found in 2.3% of the samples. cholera enterotoxin was not found in cell-free filtrates of the 100 isolates t ... | 1987 | 3606111 |
| [acoustic indicator of membrane potential levels]. | 2013 | 3609385 | |
| pentapeptide nuclear localization signal in adenovirus e1a. | the adenovirus e1a gene products are nuclear proteins important in transcriptional control of viral functions during infection. by producing normal e1a proteins and derivatives of e1a in bacteria and microinjecting these proteins into cultured cells, we were able to examine their ability to localize to the nucleus. we showed that a short peptide sequence at the carboxyl terminus of e1a is necessary for the rapid (30-min) nuclear localization of that protein. additionally, we showed that just the ... | 1987 | 3614197 |
| temporal lobe epilepsy with schizophrenia. | i have reported a case of coexisting schizophrenia and complex partial seizures to augment earlier reports of schizophrenia and psychomotor seizures masquerading as one another. i have attempted to clarify the differential diagnosis and reinforce the need to do thorough studies in such cases. | 2013 | 3616704 |
| three generations building on history. | 2013 | 3622966 | |
| [vesico-uterine fistulas]. | 2013 | 3623249 | |
| na+ modulates the k+ permeability and the membrane potential of alkalophilic bacillus. | in the absence of na+ in the medium, the membrane potential of obligately alkalophilic bacillus cells was found to be decreased by the addition of k+ to the medium, whereas k+ addition in the presence of na+ had no effect. rb+ showed essentially the same effect as k+. the decreased membrane potential was quickly restored by lowering the k+ concentration in the medium or by adding na+ or li+ to the medium. thus, in the absence of na+, the membrane potential of alkalophilic bacillus seems to be af ... | 1987 | 3663674 |
| toxigenicity and drug sensitivity of vibrio mimicus isolated from fresh water prawns in bangladesh. | 1986 | 3668195 | |
| toxin production by vibrio mimicus strains isolated from human and environmental sources in bangladesh. | vibrio mimicus has recently been isolated from aquatic environments of bangladesh. a total of 125 of 300 environmental isolates, representing various biotypes, and 19 human isolates were tested for enteropathogenicity by using several models. less than 1% of the environmental isolates and slightly more than 10% of the clinical isolates produced cholera toxin-like toxin. a significant percentage of the environmental isolates (25%) and of the human isolates (74%) induced fluid accumulation in liga ... | 1987 | 3693548 |
| [clinical chemistry of the cerebrospinal fluid]. | 2013 | 3720593 | |
| seasonal distribution of facultatively enteropathogenic vibrios (vibrio cholerae, vibrio mimicus, vibrio parahaemolyticus) in the freshwater of the elbe river at hamburg. | between june 1981 and december 1982 the incidence of vibrio cholerae, v. mimicus and v. parahaemolyticus was determined at two sampling sites on the elbe river at hamburg. a total of 183 strains was isolated from 147 water samples. of these, 107 belonged to non-01 v. cholerae (ten strains producing a cholera-like enterotoxin); 33 were identified as v. mimicus, including two enterotoxin producers; 42 strains were kanagawa-negative cultures of v. parahaemolyticus; and one was v. fluvialis. the hig ... | 1986 | 3722029 |
| anticandidal activities of terconazole, a broad-spectrum antimycotic. | terconazole is a new triazole ketal derivative with broad-spectrum in vitro and in vivo antifungal activities. this study further characterizes the effects of terconazole in vitro on yeast cell growth, viability, and morphology. terconazole inhibited the growth of candida albicans atcc 44859 in a concentration-related manner, but with modest effects noted at levels from 10(-8) to 10(-5) m when the yeast was grown on media favoring the cell form. the inhibitory potency of terconazole on yeast cel ... | 1986 | 3729366 |
| diagnosis and treatment of chalazia. | a patient with recurrent chalazia is described. this patient also had acne rosacea. the clinical and histologic characteristics of chalazia are described. in addition, therapy for chalazia is presented, with emphasis being given to conservative therapy. | 2013 | 3734179 |
| the binding of pirenzepine to digitonin-solubilized muscarinic acetylcholine receptors from the rat myocardium. | the binding of pirenzepine to digitonin-solubilized rat myocardial muscarinic acetylcholine receptors has been examined at 4 degrees c. solubilization produced only small changes in the binding of n-methylscopolamine and atropine. in contrast to the low affinity binding of pirenzepine found to be present in in the membranes, high affinity binding was detected in the soluble preparation. in both preparations, pirenzepine binding was complex. high affinity pirenzepine binding (kd approximately 3 x ... | 1986 | 3754173 |