Publications

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immune response and antioxidant status of portunus trituberculatus inoculated with pathogens.the white spot syndrome virus (wssv), vibrio parahaemolyticus and v. alginolyticus are serious epidemic pathogen affecting the cultured portunus trituberculatus and resulted in severe economic losses to local farmers. the immune and antioxidant systems are believed to be closely involved in host responses to pathogens in aerobic animals, including crustaceans. in order to explore such host-pathogen interactions in the early stage of infection in p. trituberculatus, the mrna transcript levels of ...201728235638
designation of pathogenic resistant bacteria in the sparusaurata sea collected in tunisia coastlines: correlation with high performance liquid chromatography-tandem mass spectrometry analysis of antibiotics.vibrio is characterized by a large number of species and some of them are human pathogens causing gastro intestinal and wound infections through the ingestion or manipulation of contaminated fishes including vibrio parahaemolyticus and vibrio alginolyticus. in this study, we reported the phenotypic and molecular characterization of vibrio parahaemolyticus and vibrio alginolyticus strains isolated from wild and farm sea bream (sparus aurata l.) along the tunisian coast from december 2015 to april ...201728062288
dietary yeast sterigmatomyces halophilus enhances mucosal immunity of gilthead seabream (sparus aurata l.).a yeast was isolated from hypersaline sediments, grown and phylogenetically characterized as sterigmatomyces halophilus strainn16. the dietary administration of this yeast was studied for its effect on skin mucosal immune and antioxidant status of gilthead seabream (sparus aurata l.). fish were fed a commercial diet (control, non-supplemented diet), or the same commercial diet supplemented with 0.55% or 1.1% of yeast for 15 and 30 days. one month after the end of the trial, fish from all treatme ...201728315392
hctoll3 was involved in anti-vibrio defense in freshwater pearl mussel, hyriopsis cumingii.toll-like receptors (tlrs) play an important role in the activation of innate immune response but their functions in bivalves remain largely unknown. in this study, we identified a tlr from the freshwater pearl mussel hyriopsis cumingii (hctoll3) and investigated its functions in immunity. the full-length cdna of hctoll3 is 3852 bp and includes an open reading frame (orf) of 3228 bp that encodes a polypeptide of 1075 amino acids. the predicted hctoll3 protein shares similar structural characteri ...201728214599
identification and functional analysis of a tep gene from a crustacean reveals its transcriptional regulation mediated by nf-κb and jnk pathways and its broad protective roles against multiple pathogens.thioester-containing proteins (teps) are present in a wide range of species from deuterostomes to protostomes and are thought to be involved in innate immunity. in the current study, a tep gene homologous to insect teps (itep) from the crustacean litopenaeus vannamei, named lvtep1, is cloned and functionally characterized. the open reading frame (orf) of lvtep1 is 4383 bp in length, encoding a polypeptide of 1460 amino acids with a calculated molecular weight of 161.1 kda lvtep1, which is most s ...201728069434
mice with streptozotocin-induced hyperglycemia are susceptible to invasive enteric bacterial infection.diabetes mellitus and diarrhea are becoming increasingly burdensome worldwide, particularly in developing countries such as india. diabetic patients are susceptible to infection with pathogenic bacteria, particularly those causing invasive enteric infections. in this study, we observed changes in the pathophysiological features of mice with streptozotocin-induced hyperglycemia. in our experiments, both hyperglycemic and control mice were infected with pathogenic enteric bacteria-non-typhoidal sa ...201727169940
a novel anti-lipopolysaccharide factor spalf6 in mud crab scylla paramamosain exhibiting different antimicrobial activity from its single amino acid mutant.in crustaceans, anti-lipopolysaccharide factors (alfs) are important immune effectors that have sequence diversity and exhibit broad antimicrobial activities. in this study, we characterized a novel alf homolog spalf6 from mud crab scylla paramamosain and its variant spalf6-v, which was generated by mutations of two amino acids (h46 to r and a110 to p) due to the presence of two single nucleotide polymorphisms (snps). spalf6 was an anionic peptide with isoelectric point (pi) 6.79, whereas spalf6 ...201728232132
impact of farm management on expression of early mortality syndrome/acute hepatopancreatic necrosis disease (ems/ahpnd) on penaeid shrimp farms in thailand.asian shrimp farming industry has experienced massive production losses due to a disease caused by toxins of vibrio bacteria, known as early mortality syndrome/acute hepatopancreatic necrosis disease (ems/ahpnd) for the last 5 years. the disease can cause up to 100% cumulative pond mortality within a week. the objective of this study was to identify factors associated with ahpnd occurrence on shrimp farms. a case-control study was carried out on shrimp farms in four provinces of thailand. factor ...201727594170
[growth and survival of total and pathogenic vibrio parahaemolyticus in american oyster (crassostrea virginica) under cold storage].to quantify vibrio parahaemolyticus densities in american oyster (crassostrea virginica) under cold storage.201726302123
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