Publications

transcription and translation in a pleiotropic streptomycin-resistant mutant of escherichia coli.	the role of the ribosomal protein s12 (streptomycin protein) in ribosome function and in other metabolic processes in the cell has been investigated. a spontaneous streptomycin-resistant strain of escherichia coli (sm3) carrying a mutation in the rpsl gene is deficient in its ability to induce the synthesis of the enzyme bets-galactosidase. it was demonstrated that the reduced rate of enzyme synthesis results from deficiencies in both the transcription of the lactose operon and translation of th ...	1979	104958
separation and characterization of highly purified forms of liver microsomal cytochrome p-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene.		1979	105007
implications for adult roles from differential styles of mother-infant bonding: an ethological study.	ethological observations of maternal and infant behaviors of nine vervet monkey pairs (cercopithecus aethiops sabaeus) showed the effects of differential styles of early maternal responsiveness on later infant competence. those infants receiving the least amount of maternal responsiveness and the most time-off the mother in the first 3 months of development were more socially competent at 6 months of age. the results are discussed within current ethological "attachment" theories. the detachment ...	1979	105083
prophylactic antibiotics in surgery. practices within surgical services of the veterans administration.	a survey of prophylactic antibiotic-prescribing habits among chiefs of surgical services of the veterans administration yielded a 99% response. these responses have been compared with guidelines set by an expert committee on antimicrobial use for the va central office. assuming that 100% concordance with the standards of the committee is a desired state, the average hospital is approximately one third away from this goal (average score, 62.4%). the majority of errors were those of overuse rather ...	1998	105162
[hemodialysis and nursing. 2. indication for hemodialysis].		1998	105196
immunocytochemical characterization of the lymphocytes in nodular lymphoid hyperplasia of the bowel.	the immunoglobulin constituents of hypertrophied lymphoid nodules in the intestinal tracts of six patients with the variable immunodeficiency syndrome and one patient with selective iga deficiency were evaluated by the peroxidase-labeled antibody technique. the nodules were found to contain a dense population of igm-bearing lymphocytes and much intercellular igm. evidence that the cells were engaged in igm synthesis was the presence of the immunoglobulin in the perinuclear spaces and endoplasmic ...	1998	105208
case report: intestinal clearance of calcium and protein in waldenstrom's macroglobulinemia.	a 63-year-old man with waldenstrom's macroglobulinemia had severe steatorrhea, marked protein-losing enteropathy, and excessive endogenous fecal calcium clearance. the malabsorption and protein loss resulted in weight loss and hypoalbuminemia. in contrast, the striking enteric calcium loss was completely compensated by an increase in calcium absorption resulting in a positive calcium balance.	1978	105640
[stimulation with automatic radiofrequency scanning in the long term treatment of tachyarrythmias].	a pacemaker is described which uses radiofrequency signals for synchronisation and pacing, and seeks automatically the phase of the cycle at which the tachycardia may be interrupted. the patient himself can activate the pacemaker. the programme of the external transmitter, which scans nearly all the r-r cycles of the tachycardia, may be pre-set to transmit one or two synchronised stimuli, with a progressive delay of 5 or 10 ms. if the tachycardia is interrupted the pacing stops automatically. th ...	1998	105682
fetal heart rate during a maternal grand mal epileptic seizure.	although maternal ingestion of antiepileptic drugs is strongly suspected of causing congenital defects, particularly oral clefts, the effect of epilepsy itself or a combined effect of drug intake and epilepsy have not been excluded as etiological factors. very little is known about fetal oxygenation during a maternal grand mal epileptic seizure. we describe two cases in which fetal heart rate was recorded during a maternal epileptic seizure during labor. the first fetus became clearly asphyctic ...	1998	106102
polychlorinated biphenyl-induced morphologic changes in the gastric mucosa of the rhesus monkey.	the early morphologic events in polychlorinated biphenyl-induced lesions of the gastric mucosa of immature male rhesus monkeys (macaca mulatta) were studied in serial biopsies taken during consumption of diets containing 3, 10, 30, and 100 mg. per kg. (p.p.m.) of aroclor 1242. the severity of the lesions correlated directly with both the duration and the level of exposure. the first changes were seen after ingestion of 30 and 100 mg. per kg. for 2 weeks; changes were not seen until 10 weeks at 3 ...	1979	106183
catheter cervical vertebral venography.	cervical vertebral venography using catheterzation via the femoral vein was carried out in 78 cases. in disc disease the internal vertebral venous plexus (ivvp) are interrupted at single or multiple levels, and sometimes completely blocked. in ossification of posterior longitudinal ligament, the ivvp are separated bilaterally and interrupted at multiple levels due to centrally situated ossification and associated osteophytes. venography helps to determine the upper and lower limits of laminectom ...	1998	106325
[comparative study of methods for the bacterioscopic diagnosis of tuberculosis and of methods for determining drug sensitivity].		1979	106383
cerebrospinal fluid-, blood-, and ascitis-catecholamines in hepatic cirrhosis.	the consideration of the extensive innervation of liver parenchyma, together with data relating to the degradation of catecholamines in the liver and the importance of hepatic vascular process in hepatic cirrhosis, prompted us to investigate the behaviour of catecholamines in this condition. the following parameters were measured in cerebrospinal fluid (csf), blood and ascitis fluid: total catecholamines, adrenaline and noradrenaline. during hepatic cirrhosis, total catecholamines level in blood ...	1998	106413
effects of morphine withdrawal on food competition hierarchies and fighting behavior in rats.		1979	106426
staging of myeloma. a preliminary study of staging factors and treatment in different stages.	attempts were made to find prognostic factors in myeloma. in 16 deceased patients, urinary light chains, skeletal lesions, and the quantity of the monoclonal protein fraction in the serum were correlated to prognosis, in contrast to the electrophoretic mobility of the monoclonal fraction, the hemoglobin, the serum creatinine value, the serum calcium, or the intestinal calcium absorption. skeletal calcium uptake was only numerically higher in mild myeloma than in advanced myeloma. since these fin ...	1998	106448
increased insulin sensitivity and cellular insulin binding in obese diabetics following treatment with glibenclamide.	the aim of the present study was to examine the effect of glibenclamide on the insulin receptors, the insulin sensitivity and the insulin secretion in obese non-ketotic diabetics. two groups of 9 obese diabetics were studied before and after 10 days' treatment with a 1200 kcal's diet and a 1200 kcal's diet + 10 mg/day of glibenclamide, respectively. in the group treated with diet alone we found no significant alteration of the insulin secretion pattern (p greater than 0.1). however, the insulin ...	1998	106617
radiographic changes of the skull in sickle cell anemia.	skull radiographs of 194 patients from 4 months to 55 years old with sickle cell anemia revealed porous decreased bone density in 25%, widening of diploë associated with a relative decrease in the width of the outer table in 22%, and vertical "hair-on-end" striations in 5%. the youngest patient with vertical striations was 5 years old and the oldest was 39. serial examinations in 60 patients revealed no decrease of the skull width nor disappearance of the striations with age.	1998	106639
carboxypeptidase of streptomyces griseus. implications of its characteristics.		1979	106886
radiation in multidisciplinary treatment of children with malignant ovarian tumors.	thirteen girls with malignant ovarian tumors treated at memorial hospital from august 1971 through october 1975 with extensive surgery, multi-drug chemotherapy (t-2 protocol) and postoperative radiation were reviewed. the plan of radiation was to deliver 3,000 rads to the whole abdomen and boost the para-aortic and pelvic area with 1,500 rads in five to six weeks. in only two patients was the radiation conducted as planned. in others the treatment was either interrupted or discontinued due to co ...	1998	106952
[the cranio-carpo-tarsal dysplasia syndrome in a 6-year-old girl (whistling-face syndrome)].		1998	106974
penicillin-resistant gonorrhea.		1979	106997
[continuous measuring of intracranial pressure (icp) via epidural pressure transducer (author's transl)].	continuous epidural monitoring of icp was performed on 20 patients during a 6 day's period with the model 77450 of philips. a significant decrease of intracerebral pressure after application of sorbitol and dexamethasone could be demonstrated. comparing the very low rate of complications with the resulting advantages, the described method can be recommended for controlled treatment of elevated icp.	1998	107014
acquired red cell pyruvate kinase deficiency in acute leukemias.		1998	107074
overall pathway of mononucleosome production.	five electrophoretically distinguishable classes of mononucleosomes (mi, mii, ...mv) are produced upon treatment of mammalian nuclear chromatin with micrococcal nuclease. these five forms differ in their initial dna lengths, relative mass proportions, stability, contents of histone h1, and presence of certain nonhistone proteins. a new "chromatin fingerprinting" technique has been developed in order to trace nuclease-mediated interconversions between these mononucleosomes and their polynucleosom ...	1979	107168
electron capture gas-liquid chromatographic-mass spectral identification of acids produced by neisseria meningitidis in a defined medium.	the acid metabolites and the cellular fatty acids of three strains of neisseria meningitidis grown in a chemically defined liquid medium were determined with computerized frequency-pulsed electron capture gas-liquid chromatography. five acids not previously reported were subsequently identified: isobutyric, octanoic, decenoic (c10:1), dodecenoic (c12:1), and tetradecenoic (c14:1). these acids were produced during active metabolism and were not detected as cellular constituents. the frequency-pul ...	1979	107187
halophilic, lactose-positive vibrio in a case of fatal septicemia.	a halophilic vibrio species was isolated from blood cultures from a 59-year-old male with enteritis. the strain differed from vibrio parahaemolyticus and vibrio alginolyticus by its ability to ferment lactose, its production of beta-galactosidase, and its lower nacl tolerance. a report of this infection and a description of the isolate is presented.	1979	107189
the mental health of nuclear submariners in the united states navy.		1998	107489
radical scavenging as the mechanism for stimulation of prostaglandin cyclooxygenase and depression of inflammation by lipoic acid and sodium iodide.	certain radical-trapping reducing agents have been shown to stimulate prostaglandin biosynthesis in vitro (1--6) and to depress phorbol myristate acetate-induced mouse ear edema (16). the increased prostaglandin synthesis resulted from influences on the cyclooxygenase. to ascertain whether these alterations were due to direct interaction with the enzyme or to indirect scavenging of the oxidant released during pgg2 reduction, we report the effects of lipoic acid and sodium iodide. both of these a ...	1978	107544
enteric infections in singapore with special reference to typhoid.	a review of the epidemiological features of the more important enteric infections in singapore was given. enteric fevers (typhoid and paratyphoid), salmonella gastroenteritis and shigellosis remained endemic at a rather constant level in spite of vast improvement in environmental sanitation, but amoebic dysentery showed marked decline. vibrio parahaemolyticus is an important cause of food poisoning since it was first reported in 1973. el tor cholera is believed to be introduced through regional ...	1978	107597
a vest for ambulatory patients receiving hyperalimentation.	there have been no significant complications related to the use of this ambulatory hyperalimentation vest. the potential positive impact that increased use of this vest at home might have upon hospital stay and cost containment is obvious. it is further anticipated that, as advances are made in the technology of plastic bags, tubing, miniature pumps and microprocessors, ambulatory or home hyperalimentation delivery systems exemplified by this vest will achieve a much higher degree of sophisticat ...	1998	107602
a three month inhalation toxicity study in the squirrel monkey (saimiri sciureus) with terbutaline sulfate (bricanyl).	a study of the subacute toxicity of inhaled terbutaline sulfate was performed in the squirrel monkey (saimiri sciureus). 3 groups of monkeys were exposed 1 h daily 7 days/week for 3 months to terbutaline sulfate aerosols at concentrations of 0.039, 0.185 and 0.799 mg terbutaline/litre of air respectively. a fourth group was a chamber control receiving air only. the following clinical parameters were evaluated: physical appearance and behavior, weight gain, ophthalmoscopic appearance, electrocard ...	1978	107616
pituitary-thyroid function in spironolactone treated hypertensive women.	four weeks high dose spironolactone treatment (aldactone searle, 100 mg q. i. d.) significantly enhanced the tsh (delta max. 8.5 +/- 4.1 vs. 4.6 +/- 3.1 microunits/ml, p less than 0.05) and t3 (delta max. 32 +/- 27 vs. 11 +/- 16 ng/100 ml, p less than 0.05) responses to an intravenous trh/lh-rh bolus injection in 6 eumenorrhoeic euthyroid hypertensive women, without affecting basal serum tsh, t3 or t4 levels or the basal and stimulated lh, fsh and prolactin values (p greater than 0.10). the mean ...	1979	107696
first year radiology residents: pgi vs. pgii.		1998	107768
experimental transmission of wuchereria bancrofti to monkeys.	infective larvae of wuchereria bancrofti from laboratory-raised culex pipiens fatigans and aedes togoi mosquitoes fed on human volunteers in jakarta, indonesia (j strain) and kinmen island, china (k strain) were introduced into taiwan monkeys (macaca cyclopis) by subcutaneous inoculation, by foot puncture, or by permitting infected mosquitoes to feed weekly on the monkeys. some animals were splenectomized and others were treated with varying regimens of immunosuppressants. necropsy was done on m ...	1979	107818
isolation of listeria monocytogenes from animals in the sudan.		1979	107996
transport of neisseria meningitidis cultures: growth-supporting media and freezing as an alternative.	the abilities of transgrow (tg), thayer-martin (tm), and new york city (nyc) solid media to maintain the viability of 12 strains of neisseria meningitidis under various controlled conditions were assessed. the effects of charcoal impregnation of swabs, temperature, and an enriched co2 atmosphere were examined with holding for up to 21 days. recovery from samples held at 35 degrees c was, in almost all instances, greater than at 22 or 4 degrees c. a strong requirement for added co2 was demonstrat ...	1979	108008
pole cells of drosophila melanogaster in culture. normal metabolism, ultrastructure, and functional capabilities.		1998	108161
gray scale sonography of cystadenoma of the pancreas: report of two cases.		1998	108314
[heredity in eye diseases. ii. foundations of ophthalmological genetics (author's transl)].		1998	108459
immobilization of pyridoxal 5'-phosphate and pyridoxal 5'-phosphate-dependent enzymes on sepharose.		1979	108513
[colo-rectal carcinomas: a challenge].		1998	108581
a preliminary assessment of possible mutagenicity of betel nut and ingredients of the betel quid when administered alone or in combinations to larvae of drosophila melanogaster.	the "carcinogenic" betel nut and constituents of betel quid were tested for possible mutagenicity in drosophila. the test compounds were administered either alone or in combinations by larval feeding. the data on sex-chromosome loss, sex-linked recessive lethals and autosomal translocations suggest lack of mutagenicity.	1998	108597
the use of acupuncture needles as sphenoidal electrodes in electroencephalography: a reappraisal.		2000	110550
esterification of cholesterol in human small intestine: the importance of acyl-coa:cholesterol acyltransferase.	human intestinal mucosa contains acyl-coa:cholesterol acyltransferase activity. the enzyme has been studied by using oleylcarnitine, coa and carnitine palmitoyltransferase as an oleyl-coa regenerating system. the enzyme was found in the particulate fraction of the cells, it had a ph optimum between 7.2 and 8.2, and was inhibited by taurocholate. the specific enzymic activity in biopsies from intestinal mucosa of normal men was found to be 3.6 +/- 1.37 nmol cholesteryl ester formed mg protein-1 h ...	1979	110602
long term survival following firearm injury to the head.		2000	110996
membrane potential and reconstitution.		1979	110998
infectious diarrhea.		1979	111270
progressive-ratio performance in the rhesus monkey maintained by opiate infusions.		1979	111282
interaction of alcohol and reward in an achievement situation.	effects of psychological stress on acute alcohol intoxication following intake of 2 ml whisky/kg body weight were examined in 12 healthy subjects. each subject performed a 45-min psychomotor task under four conditions, two of which increased achievement stress by promising the subject a monetary reward for rapid and accurate performance. the conditions were (a) task only, (b) task + reward, (c) task + alcohol, and (d) task + reward + alcohol. in condition (b) reward improved performance and heig ...	2000	111286
results of cytostatic therapy of metastasizing testicular tumors.		2000	111320
differences in length of hospital stay for medicaid and blue cross patients and the effect of intensity of services.		2002	113844
sensitization of myelinated nociceptive afferents that innervate monkey hand.		1979	115969
oligoclonal igg and virus antibodies in cerebrospinal fluid in progressive myoclonus epilepsy.		2002	117579
oligoclonal igg and virus antibodies in cerebrospinal fluid in progressive myoclonus epilepsy.		2002	117579
carbamazepine serum levels in children with epilepsy: a micro immuno-assay technique.	in part 1 of this study, 26 children with seizures were given 20 mg/kg/day carbamazepine and five developed side-effects. with this initial dose, equilibrium was reached in the serum within four to six days in 25 of the 26 children. the sudden withdrawal of other anticonvulsants did not usually affect the rise of carbamazepine in serum, unless given in high doses. in part 2 of the study it was shown that satisfactory levels were obtained in the serum of 38 children given carbamazepine either twi ...	2002	118072
purification and characterization of a hemolysin produced by vibrio cholerae biotype el tor: another toxic substance produced by cholera vibrios.	a thermolabile direct hemolysin from an el tor cholera vibrio strain has been isolated and partially characterized as a simple protein of ca. 20,000 molecular weight. in addition to its hemolytic activity, the hemolysin is cytotoxic, cardiotoxic, and rapidly lethal. in these respects it resembles the thermostable direct hemolysin/cytotoxin/cardiotoxin/lethal toxin of vibrio parahaemolyticus and certain other bacterial hemolysins, although there are other significant differences. because identica ...	1979	118926
cellular immunity in protein malnutrition: differences in in vivo and in vitro responses.		1979	120012
distribution of membrane-bound monoamine oxidase in bacteria.	the distribution of membrane-bound monoamine oxidase in 30 strains of various bacteria was studied. monoamine oxidase was determined by using an ammonia-selective electrode; analyses were sensitive and easy to perform. the enzyme was found in some strains of the family enterobacteriaceae, such as klebsiella, enterobacter, escherichia, salmonella, serratia, and proteus. among strains of other families of bacteria tested, only pseudomonas aeruginosa ifo 3901, micrococcus luteus ifo 12708, and brev ...	1979	120132
[reflection of hydroelectrolytic replacement prior to parenteral feeding].		2002	120569
epidemiology of diarrhoeal diseases in singapore.	diarrhoeal diseases in the form of bacterial food poisoning are prevalent in singapore. common food poisoning organisms implicated were staphylococcus aureus, non-thypoid salmonellae and vibrio parahaemolyticus. el tor cholera, believed to be introduced through intra-regional trade and travel, occurred sporadically with a common source outbreak, probably food-borne, in september 1978. shigellosis and amoebiasis were mainly confined to areas where poor personal hygiene was prevalent. the incidenc ...	1979	120734
[oculomotor reflex evoked by vibrassae stimulation in the cat].	the oculomotor effects of vibrissae stimulation have been studied in the "encéphale isolé" non-anaesthetized cat. intracellular recording of lateral rectus motoneurones showed an excitatory projection via the ipsilateral infraorbital nerve to these motoneurones. the afferent fibers are type a alpha, recuited with a low threshold (0.2-0.5 ma) and convey information about vibrissae displacement.	1979	120789
enzymic synthesis of steroid sulphates. xi. study of the oestrogen binding site of oestrogen sulphotransferase by affinity labelling with 4-mercuri-17beta-oestradiol.	oistrogen sulphotransferase (3"-phosphoadenylylsulphate: oestrone sulphotransferase, ec 2.8.2.4) contains asingle sulphydryl group thought to be at, or near, the oestrogen-binding site. 4-mercuri-17beta-oestradiol, the activity of the enzyme decreased with increasing concentration of the oestrogen derivative. however, some 40% of the activity remained when all the sulphydryl had reacted to form mercaptide. formation of mercaptide was only marginally decreased in the presence of the substrate 17b ...	1975	123774
inhibitory effect of normal mammalian sera on the rosette formation of human lymphocytes with sheep red blood cells.		1975	123840
[endogenous factors in acquired cochlear deafness in adults].		2002	123939
[valve of the study of the mechanism of discoveries. apropos of some medical discoveries, including ménière's disease and perforation of the tympanum by astley-cooper].		2002	123949
metabolic clearance rate, production rate and mammary uptake of progesterone in the goat.	the dynamics of progesterone uptake and metabolism in the mammary gland of the goat have been measured and related to the metabolic clearance rate and production rate of the hormone determined by tracer kinetic techniques. the metabolic clearance rate of progesterone from blood was 3-13 plus or minus 0-35 (s.e.m.) 1/min in ten experiments on six goats; values tended to be slightly higher in pregnant than in non-pregnant goats. the production rate of progesterone at oestrus, and at day 3 of the n ...	1975	124325
[pancreatic carcinoma on endoscopic retrograde pancreatico-cholangiogram (author's transl)].	the pancreaticographic appearances of carcinoma of the pancreas have been divided into two types: 1. canalicular carcinoma arising from the duct system. if arising from the main pancreatic duct, it occludes this, or causes displacement or deformity of its branches in the immediate neighbourhood. if arising from branches, it causes cystic ectasia of the minor ducts; these appear fragmented and deformed while there is stenosis and displacement of the main duct. simultaneous origin from the main an ...	1998	124684
immunofluorescent localization of glycogenolytic and glycolytic enzyme proteins and of malate dehydrogenase isozymes in cross-striated skeletal muscle and heart of the rabbit.	specific antisera against glycogen phosphorylase, phosphofructokinase, aldolase, glyceraldehyde-phosphate dehydrogenase, enolase, lactate dehydrogenase, cytosolic and mitochondrial malate dehydrogenase from rabbit muscle were obtained from sheep. the gamma-globulins were used for indirect immunofluorescent localization of the respective enzymes in rabbit skeletal muscle and heart. in stretched skeletal muscle a cross-striation like distribution was observed for all enzymes studied. in the case o ...	1975	124716
the management of acute genitourinary infections.		1998	124723
[desmoid tumor of the abdominal wall in a young child].		2002	126412
effect of zinc and cadmium on delta-aminolevulinate dehydratase of red blood cells in protecting against enzyme losses during storage.	the effect of zinc and cadmium on delta-aminolevulinate dehydratase of bovine erythrocytes stored at -30 degrees c for different times was determined. the results show a. storage of erythrocytes leads to an enhancement of the enzyme activity, which after six weeks is 165% (500 mum zncl2) respectively 220% (100 mum cdcl2) for red blood cells of calves, and after four weeks in 420% respectively 450% (same concentrations) for red blood cells of adult cattle, b. the older the samples are, the higher ...	1975	126587
tightness and orientation of vesicles from guinea-pig kidney estimated from reactions of adenosine triphosphatase dependent on sodium and potassium ions.	in order to study the "sidedness" of the ligands of the na+, k+-atpase in the phosphorylation from [32p]atp, tight vesicles were prepared from guinea pig kidney and partially purified by a two-stage sucrose and ficoll gradient centrifugation procedure. these vesicles were derived presumably from plasma membrane fragments resealed after the initial disruption of the cells during homogenization. tightness of the vesicles was estimated according to activation by the nonionic detergent, triton x-100 ...	1975	126864
a symposium on the chronic pain syndrome in problem low back cases. psychiatric evaluation and feasibility of psychiatric therapy.		2002	127024
proceedings: observations on fragment d species arising during hydrolysis of crosslinked human fibrin.		1975	127400
direct and utilization of metabolic energy for transport processes within proximal convolution.		1975	127689
'immobile' (im), a recessive lethal mutation of xenopus laevis tadpoles.	'immobile' (im) is a recessive lethal mutation discovered in the f3 of a xenopus (xenopus laevis laevis) originating from a mesodermal nucleus of a neurula transplanted into an enucleated egg. the im embryos do not contract after mechanical stimulation nor do they present any spontaneous contraction from the neurula stage onwards. development proceeds normally during the first days after which deformation of the lower jaw and tail are observed. the im tadpoles die when normal controls are at the ...	1975	127824
[histochemical and quantitative studies of rna in the thyroid epithelium under the influence of thyrotropic hormone (tsh)].		1975	127942
[some properties of preparations of na+ and k+-atpase treated with deoxycholate].	the treatment of membrane suspension from the guinea pig kidney cortex possessing na+, + k+ -atpase activity with 0.20% sodium deoxycholate (dox : protein equals 12 : 1) leads to lowering of their enzymatic activity. dox-treated preparation can be divided into two fractions by centrigugation (1 hr - 22 000 g). the pellet has 1.5-fold higher enzymatic activity than the initial preparation and cannot be activated by small amounts of histones. the supernatant has 2-fold lower enzymatic activity tha ...	1975	128167
[histochemical studies on the angle of the anterior chamber in glaucoma. part i. primary open-angle glaucoma (author's transl)].		2002	130793
[laparoscopy of adhesions. diagnostic use].		2002	134429
allergic reaction to allopurinol with cross-reactivity to oxypurinol.	a 25-year-old white man with gout and nephropathy and with a previous reaction to allopurinol was given a trial dose of oxypurinol. he developed malaise, a generalized erythematous reaction with edema, pruritus, and emesis; this was clinically identical to the reaction he experienced with allopurinol. when the patient's lymphocytes were exposed in vitro to oxypurinol and allopurinol, increased dna synthesis was observed, suggesting an immunologic basis for the reaction. this patient indicates th ...	1976	134655
[prenatal development of monoamine neurons in the rat].	the histofluorescence method allows the study of the prenatal development of monoamines neurons in the foetal rat brain. certain patterns of this development can be defined: the locus niger and the raphe appears fluorescent on the 14th day, the locus coeruleus on the 15th day. these systems differentiate independently in various areas of the neural axis. their maturation are progressive: first for the da system, then for the na and the 5 ht systems. the mechanisms for synthesis and storage of am ...	1976	134781
[influence of microflora on the metabolism of l-threonine at the level of the rat digestive tract].	intestinal tissues are found to incorporate l threonine 14cu at faster rate in the absence of microflora. most of the radioactivity of the digestive contents occurs in the tca soluble compounds, except in the coecum and large intestine of the conventional rats where the microflora synthetized its own proteins from the labelled digestive material. free threonine is the main labelled soluble compound in the conventional rats digestive contents. in the other hand, in the germfree rats digestive con ...	1976	134804
multiple forms of phosphofructokinase in animals from the phylum chordata.		2002	134863
rna biosynthesis in the chick embryo during development and its relation to collagen synthesis.	a study of rna synthesis in the legs and wings of chick embryos suggests synthesis of specific rna's as a function of development. an increase in rna at day 10 was followed by an increase in collagen synthesis. that rna had a sedimentation coefficient of 23s and several of the characteristics of mrna. thus it appeared to contain a poly a sequence since it was retained on poly u coated-filters, it was not methylated, and its synthesis was not inhibited by low doses of actinomycin d. that rna was ...	2002	134868
clinical comparison between glibornuride (glutril) and tolbutamide in maturity-onset diabetes: a controlled double-blind trial.		2002	134878
localization on mitochondrial dna of mutations leading to a loss of rutamycin-sensitive adenosine triphosphatase.	four cytoplasmic mutants of saccharomyces cerevisiae showing loss of mitochondrial rutamycin-sensitive atpase activity but having significant cytochrome oxidase and nadh-cytochrome c reductase have been isolated. genetic studies indicate the mutations to be closely linked to each other and have been assigned to a new locus, pho1. the mutations show a low frequency of recombination with the ol12 locus, suggesting a linkage to this marker. they are not, however, linked to the oli1 locus. linkage o ...	1976	134892
long-term treatment with beta-blockers after myocardial infarction.	162 patients discharged from hospital after mycardial infarction were randomly allocated to two groups, one received alprenolol 400 mg daily and the other served as the control. the period of follow-up was two years and all other treatment given was standardized. the two groups did not differ with respect to risk factors for myocardial infarction, the course of the acute infarct or treatment during follow-up. after two years one patient in the group treated with alprenolol had died suddenly as c ...	2002	134897
the acid mucopolysaccharides (glycosaminoglycans) in secondary cultures of embryonic rat fibroblasts.	in secondary cultures of embryonic rat fibroblasts the protein-free acid mucopolysaccharides were separated by cetylpyridinium chloride fractionation and identified afterwards. the following acid mucopolysaccharides were found: hyaluronic acid, chondroitin, 2 heparan sulphate fractions, chondroitin-4-sulphate, chondroitin-6-sulphate, and dermatan sulphate.	1975	134903
biochemical variations in the matrix of human tendons in relation to age and pathological conditions.	with increasing age, the human tendon shows an increase of collagen and a diminution of mucopolysaccharides and glycoproteins. similar findings have recently been reported by other authors in the tendons of mammals. fragments of tendon affected by tendinosis, obtained dlring suture and tenoplasty operations, were also examined. marked diminution of collagen and an increase of acid mucopolysaccharides and structural glycoproteins were found as compared with the control tendon.	1975	134980
[value of a therapeutic combination: vitamin a-yeast-sulfur].		1976	135073
[details of a denounced physician (e.n.t.) suspected of bodily injury, and the following expert judgement (author's transl)].	an otologist was denounced and the patient's case history was confiscated because after tonsillectomy an absecess and a thrombosis of the vena jugularis interna had developed. the procedure and the medical aspect how at first being judged by the lawyer and the public prosecutor are described. on the base of the given medical opinion the court quashed proceedings. because of the growing number of denouncements this casuistic paper ends with four guiding principles to protect against unjustified m ...	2002	135139
[responsiveness of lymphocytes to stimulation by pha and autologous blasts in acute lymphatic leukemias during remission (author's transl)].	the paper deals with the question how far the lymphocytes of acute lymphatic leukemia patients in remission can be stimulated by pha and autologous blasts in the mlc-test. the lymphocyte stimulation by pha showed considerable variation dependent on the phase of therapy. a significant reduction of the responsiveness to pha stimulation was found during the prophylactic reinduction treatment with vincristin and prednisolon compared with the results during maintenance therapy. the examination of lym ...	2002	135240
transplantation of hymenolepis diminuta into naive, immune and irradiated mice.	almost 100% of 7- to 10-day-old hymenolepis diminuta became established when surgically transplanted from donor mice into the duodenum of naive recipient mice. transplanted tapeworms survived 8-12 days, by which time they had survived much longer in total than they would have done in the donor. mice previously immunized by a primary infection rejected transplants within 4 days. sub-lethal irradiation (550 rad) delayed rejection by immune mice but such mice still rejected worms much more quickly ...	1976	135242
[congenital entropion of the eyelids (2 clinical cases)].		2002	135290
[protective and reparative effect of deoxyribonucleic acid instilled in the cornea].		2002	135294
[late diagnosis of a nasal foreign body].		2002	135308
[public health in the russian federation during the 9th five-year plan].		2002	135354
[laparoscopy in the diagnosis of retroperitoneal non-organ tumors].		2002	135356
suppressor mechanisms in neonatally acquired tolerance to a gross virus-induced lymphoma in rats.	tolerance to a highly immunogenic gross virus-induced tumour in wistar/furth rats (c58nt)d was produced by neonatal infection of the rats with the virus. these rats failed to reject the tumours when challenged 8 weeks after virus inoculation and to mount the appropriate cell-mediated immune response to the tumour. the mechanisms involved were studied in vivo by adoptive transfers into sub-lethally irradiated rats of tumour cells mixed with spleen cells and/or sera from normal, tolerant, or tumou ...	1976	135385