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gardner's syndrome with bilateral osteomas of coronoid process resulting in limited opening. 20123472187
vibrio alginolyticus bacteremia in an immunocompromised patient.vibrio alginolyticus, an extremely halophilic member of this genus, was isolated from multiple sets of blood cultures drawn during a septic crisis of a patient with osteogenic sarcoma. no identifiable source of this infection could be determined.19863465495
[human gingival pigmentation due to electrochemical degradation. immunological study of biopsies using monoclonal antibodies]. 19863464603
development and characterization of a rat histiocyte-macrophage tumor line.a transplantable macrophage-like cell line has been obtained and established in w rats. this cell line is in its 85th passage and is perhaps the only established macrophage-like cell line that grows rapidly intraperitoneally in rats. the cells possess some of the typical characteristics of macrophages, such as adherence to glass, phagocytosis, presence of fc receptors and c3d receptors, la determinants, leukocyte common antigen, lysozyme, non-specific esterase, and glycogen. the tumor also grows ...19863457975
paroxysmal myoclonic dystonia with vocalisations: new entity or variant of preexisting syndromes?from among 1377 patients with movement disorders, four patients had an unusual movement disorder characterised by paroxysmal bursts of involuntary, regular, repetitive, rhythmic, bilateral, coordinated, simultaneous, stereotypic myoclonus and vocalisations, often associated with tonic symptoms, interference with voluntary functioning, presence of hyperactivity, attention and learning disabilities, and resistance to treatment with haloperidol and other drugs. this symptom complex may represent a ...20123457101
[studies on the blood constituents of the neonates delivered by the induced delivery of the defense medical college method].for the assessment of the influence of the defense medical college planned delivery method upon neonates, the measurement of the blood constituents of the umbilical cord was conducted. statistically speaking, no marked differences were seen between the neonates delivered by the defense medical college method and neonates delivered naturally. the blood constituents investigated were: blood cells, activity of various enzymes, other blood constituents and electrolytes.20123457089
sensitivity and uncertainty studies of the crac2 computer code.we have studied the sensitivity of health impacts from nuclear reactor accidents, as predicted by the crac2 computer code, to the following sources of uncertainty: (1) the model for plume rise, (2) the model for wet deposition, (3) the meteorological bin-sampling procedure for selecting weather sequences with rain, (4) the dose conversion factors for inhalation as affected by uncertainties in the particle size of the carrier aerosol and the clearance rates of radionuclides from the respiratory t ...20123444936
[new therapeutic possibilities in idiopathic nephrotic syndrome relapse]. 20123440223
the prevalence of congenital abnormalities in patients with positive contraction stress tests.over a period of 10 years, 60,197 stress and nonstress tests were done in 25,313 patients. there were 229 (0.9%) positive tests. in 47.2% of patients who had positive tests, preeclampsia and hypertension were the indications for the test, followed by suspected intrauterine growth retardation (26.6%) (table i). the cesarean section incidence was 71%. the mean age of the patients was 32 years. nine per cent of patients were 45 years or older, 7% between 40 and 44 years, 23% between 35 and 39 years ...20123430326
vibrio alginolyticus and diarrhoeal disease. 19873429796
collagen binding in clinical isolates of staphylococcus aureus.collagen binding was examined in 90 strains of staphylococcus aureus derived from patient samples. slightly under one-half (39 of 90) of the s. aureus strains bound collagen. collagen binding in s. aureus did not correlate with either immunoglobulin g or fibronectin binding by these organisms. chi-square analysis of isolates obtained from patients with complicated bacteremia (bacteremia associated with deep tissue infection) compared with isolates from patients with uncomplicated bacteremia (bac ...19873429618
effect of pre- and postnatal exposure to alcohol on perivenous and periportal neonatal rat hepatocytes.hepatocytes from 12-day-old rats, pre and postnatally exposed to alcohol and pair-fed controls, were isolated and subfractionated in six cell subpopulations on percoll density gradients. these cells were characterized using biochemical, stereological and cytofluorometric methods. our results show that the low density cells (f2) are mainly perivenous cells, whereas the heavier cells (f6) were primarily periportal cells. these results were confirmed by alanine aminotransferase (alat), and glutamat ...19873426691
use of mild detergent gel electrophoresis for isolation and characterization of the kidney brush border d-glucose transporter.gradient gel electrophoresis was performed under mild detergent conditions to separate pig kidney brush border membrane proteins and to identify the smallest functional molecular protein entity of the d-glucose transporter. the various protein bands obtained from the nondenaturing gel system in a semipreparative scale were eluted by electrodialysis. these proteins were then reintegrated into proteoliposomes and tested for d-glucose-inhibitable [3h]phlorizin binding. the d-glucose transporter had ...19873425911
the role of ct in the management of carcinoma of the oesophagus and cardia. 20123408181
thyroglobulin and 131i uptake of remaining tissue in patients with differentiated carcinoma after thyroidectomy.in 158 thyroidectomized patients with well-differentiated non-metastatic thyroid cancer the results of serum thyroglobulin (tg) determination and 131i uptake values established immediately before radioiodine treatment (19 days after surgery) were compared. in 113 patients (72%) tg was above 6 ng ml-1 (lower limit of detection) and 131i uptake exceeded 2%. in 11 patients (7%) tg was undetectable and 131i uptake less than 2%. in these cases a radioiodine treatment was not performed; the thyroid ab ...20123399222
a new use of instrumentation in fluoroscopy controlled heel spur surgery. 20123397874
obese binge eaters: affect, cognitions, and response to behavioural weight control. 20123397436
prograde versus retrograde endoscopic laser therapy for the treatment of malignant esophageal obstruction: a comparison of techniques.the prograde and retrograde approaches to the treatment of malignant esophageal obstruction with the nd:yag, or neodymium: yttrium, aluminum, garnet, laser are compared. with the prograde technique, tumor destruction proceeds from the proximal to the distal tumor margin. in retrograde treatment, the endoscope is passed to the distal tumor margin so that the treatment can proceed in the reverse direction, thereby completing therapy in a single treatment session. this is usually accomplished by pa ...20123393057
progesterone regulation of secretory component (sc): uterine sc response in organ culture following in vivo hormone treatment.sex steroid hormones are known to have profound effects on mucosal immunity. in the present study we evaluated the effects of progesterone on the uterine immune system by determining the changes in the levels of secretory component (sc) released from uterine tissues in culture following in vivo administration of progesterone to estradiol-stimulated ovariectomized rats. sc is a transport protein which moves iga into external secretions such as intestinal and uterine secretions. sc release was det ...19883386246
risk assessment for acquiring meningitis tuberculosis among children not vaccinated with bcg: a case-control study.this case-control study was conducted to assess the risk, among children aged 0-12 years, of developing meningitis tuberculosis (mt) associated with a lack of intradermal bcg vaccination. cases (45) of mt admitted for treatment at the fundacao benjamin guimaraes hospital (belo horizonte, mg, brazil), from 1975 to 1981, were matched for age at hospitalization, date of hospitalization and nutritional status, with two types of controls--patients with acute diarrhoea (ad) and patients with acute non ...19883384537
[protein studies in cystic and peritoneal fluids of ovarian tumors with special reference to cea].the levels of total protein, ig, afp, beta-hcg, cea, sc, sp1 and alpha 2-pag were measured in cystic and peritoneal effusions obtained from 70 females with benign and malignant ovarian tumors. this study was carried out to test out parameters those are useful for tumor monitoring of ovarian cancer. our results indicate that determining cea in peritoneal effusions could be one of useful methods in tumor monitoring of mucinous cystadenocarcinomas in cases of known histology and praetherapeutic est ...20123376613
[long-term results of the treatment of ruptured intracranial aneurysms. study of a series of 328 patients hospitalized from 1972 to 1984].between 1972 to 1984, 328 patients were admitted in the department of neurosurgery, for the treatment of a ruptured intracranial aneurysm, and being clinically in grades i to iv. these patients were submitted to a deferred surgery protocol. 5.5% of the patients died before surgery, and 94.5% were actually operated on. the follow-up was at least over one year, and up to 14 years (mean 3 years and 8 months). the long term result was appreciated according to the physical status of the patients and ...20073374722
a light and electron microscopic study of the epithelium of the extrapulmonary airways of mauremys caspica and lacerta lepida (reptilia).the epithelium of the extrapulmonary airways of a chelonia (mauremys caspica) and a squamata (lacerta lepida) was investigated by means of conventional light and transmission electron microscopy, scanning electron microscopy, histochemistry and immunocytochemistry. the epithelium of mauremys caspica is composed of basal, ciliated, endocrine and mucous cells. serotonin-immunoreactivity was detected in the endocrine cells. mucous cells were found to contain either sialo-mucins or both sialo- and s ...20123370620
energy cost and metabolic regulation during intermittent and continuous tetanic contractions in human skeletal muscle.muscle atp turnover, glycogenolytic, and glycolytic rates were estimated to compare the energy cost and glycolytic regulation of 102.4 s of continuous and intermittent stimulation. quadriceps femoris muscles of male subjects were stimulated at 20 hz for one continuous contraction (n = 6) or a series of 64 contractions (1.6 s on, 1.6 s off; n = 6). leg blood flow was occluded and muscle biopsies were obtained at rest and following 51.2 and 102.4 s of contraction time in both conditions. isometric ...19883370544
oxidation of antipsoriatic 10-acyldithranol derivatives and dithranol to 1,8-dihydroxyanthraquinone. 20123369924
comments on references to the american board of psychiatry and neurology in an article. 20023369584
tissue reaction to implant corrosion in 38 internal fixation devices.the corrosion characteristics, metallurgical properties, and clinical performance of 38 retrieved internal fixation devices were correlated with the tissue reaction to these devices. metallurgical parameters included thin and heavy inclusion content, rockwell hardness, and grain size. the excised fibrous tissue strip was directly overlying each plate at removal and sectioned between screw-hole sites. the material studied from the 38 plates consisted of 201 screw-hole junctions with associated ti ...20113368412
electrohydraulic lithotripsy of gallstones in humans. 20123366335
correcting for selection bias in estimation of within-individual variance.consider a variable whose expected value distributes among individuals in a population, and which also has an important component of within-individual variance. in a screening study that involves repeated observations only for those individuals whose initial observation exceeds an arbitrary cutoff point, the usual estimator of within-individual variance is biased. assuming normality and independence, this note gives the derivation of the expected value of the estimator and uses it to obtain an u ...20113358021
correcting for selection bias in estimation of within-individual variance.consider a variable whose expected value distributes among individuals in a population, and which also has an important component of within-individual variance. in a screening study that involves repeated observations only for those individuals whose initial observation exceeds an arbitrary cutoff point, the usual estimator of within-individual variance is biased. assuming normality and independence, this note gives the derivation of the expected value of the estimator and uses it to obtain an u ...20113358021
smooth muscle tumours of the digestive tract: report of 160 cases.of 160 patients seen in the period 1951-84 with smooth muscle tumours of the digestive tract, 71 proved to have leiomyomas, 87 had leiomyosarcomas and 2 had leiomyoblastomas. tumour diameter was frequently greater in patients with leiomyosarcoma. the surgical mortality was 2.8 per cent after treatment of leiomyoma and 10.3 per cent after treatment of leiomyosarcoma. after resection of leiomyosarcoma the 2-year survival rate was 86 per cent and the 5-year survival rate was 43 per cent. the only h ...20123349313
a theory of the symmetries of filamentous bacteriophages.a mathematical model is presented which explains the symmetries observed for the protein coats of filamentous bacterial viruses. three viruses (ff, ike, and if1) all have five-start helices with rotation angles of 36 degrees and axial translations of 16 a (type i symmetry), and three other viruses (pf1, xf, and pf3) all have one-start helices with rotation angles of approximately equal to 67 degrees and translations of approximately 3 a (type ii symmetry). the coat protein subunits in each group ...20123349133
13c nmr studies of carboxylate inhibitor binding to cobalt(ii) carboxypeptidase a.both 13c nmr and electronic absorption spectral studies on cobalt(ii) carboxypeptidase a in the presence of acetate and phenylacetate provide evidence for two binding sites for each of these agents. the transverse relaxation rate t2-1 for the 13c-enriched carboxyl groups of the inhibitors is significantly increased when bound to the paramagnetic cobalt carboxypeptidase as compared to the diamagnetic zinc enzyme. the acetate concentration dependence of t2p-1 shows two inflections indicative of se ...20123346659
sensitive non-radioactive dot-blot hybridization using dna probes labelled with chelate group substituted psoralen and quantitative detection by europium ion fluorescence.a new labelling method for cloned dna probes used in hybridization assays is described. the dna insert of recombinant plasmid dna was made partially single-stranded for the labelling reaction by a restriction enzyme digest, followed by a controlled exonuclease iii incubation. a thiol-containing psoralen derivative was covalently bound through irradiation with uv-light to the remaining double-stranded region of the plasmid dna. the psoralen-sh groups were labelled with a large number of metal che ...20123344204
patterns of plasma imipramine-desipramine concentrations in patients receiving concomitant fluphenazine decanoate.plasma levels of imipramine and desipramine were monitored in a series of 13 patients with postpsychotic depressions who had a fixed dose of imipramine (150 mg/day) added to their clinically adjusted, stable dose of fluphenazine decanoate. despite the potential for metabolic inhibition of the tricyclic drug by the neuroleptic drug, no relationship was found between the fluphenazine dose and the subsequent plasma concentrations of imipramine and desipramine. however, plasma antidepressant levels ...20123338977
transvaginal parametrial needle biopsy for detection of postirradiation recurrent cancer of the cervix.during the 27-year period from 1956 to 1982, transvaginal parametrial needle biopsies were performed on 76 patients clinically suspected of harboring postirradiation recurrent cervical cancer without mucosal lesions suitable for biopsy under direct vision. needle biopsies indicated cancer in 41 patients, resulting in 20 abdominal explorations. eleven of these patients underwent total pelvic exenteration. three patients survived longer than 5 years. among 35 patients whose biopsies did not sugges ...20123334963
[reservoirs of resistance plasmids]. 20093327947
antidesmosomal monoclonal antibody in the diagnosis of intracranial tumours.immunocytochemistry has been applied extensively to the diagnosis of intracranial tumours, but meningiomas still present a diagnostic problem. however, desmosomes have been shown by electron microscopy to be present in meningiomas, and this distinguishes them from gliomas. this paper describes a new monoclonal antibody, 11-5f, against desmosomal proteins 1 and 2 (desmoplakins) and assesses its usefulness in the diagnosis of meningiomas and other intracranial tumours. a total of 74 surgically rem ...20123323433
[neonatal polycythemia and hyperviscosity syndrome--update]. 20123322982
altered sensitivity of the gallbladder to cholecystokinin octapeptide in irritable bowel syndrome.we compared responses of the gallbladder to graded intravenous infusions of cholecystokinin octapeptide (cck-op) in normal controls (n = 8) and patients with irritable bowel syndrome (ibs) with predominant constipation (n = 8) or diarrhea (n = 8). the doses of cck-op ranged from subphysiological (negligible contraction of the gallbladder) to supraphysiological (90% contraction of gallbladder and abdominal side effects) amounts. all gallbladders contracted progressively in response to cck-op, and ...20123318495
cranial variation in european populations: a spatial autocorrelation study at three time periods.this study reports on spatial variation of 10 cranial variables in european populations at 3 time periods. means for these variables, based on 137, 108, and 183 samples from the early medieval, late medieval, and recent periods, were subjected to one-dimensional and directional spatial autocorrelation analyses. significant spatial structure was found for most variables. it becomes more pronounced as time progresses. the spatial patterns are not strongly clinal. correlograms based on distances co ...20123318489
role of alcohol use by narcotic addicts as revealed in the darp research on evaluation of treatment for drug abuse. 20123314556
[colibacillosis in calves, especially enterotoxic e. coli infections].developments in the knowledge of colibacillosis are reviewed in the series of 'papers in the past and present.' the starting-point of this paper is provided by the paper by h. veenstra:' a note on diseases of young breeding calves in the province of friesland' (1894) but particularly, by the study by j. poels: 'report on calf disease in the netherlands' which appeared in 1899. a historical review of bacteriological features in the pathogenesis of neonatal diarrhoea in calves and their significan ...19873310331
[man in prolonged space flight]. 19873307203
prevention of cardiovascular disease in the elderly. 20123298365
reversibility of decreased insulin-stimulated glucose transport capacity in diabetic muscle with in vitro incubation. insulin is not required.the mechanisms by which insulin deficiency affects muscle glucose transport were investigated. epitrochlearis muscles from rats with streptozotocin-induced diabetes and from controls were incubated in vitro for 0.5-14 h. the incubation was shown not to impair muscle energy stores or tissue oxygenation. diabetes decreased basal 3-o-methylglucose transport by 40% (p less than 0.01), and insulin-stimulated (20 milli-units/ml) glucose transport capacity by 70% (p less than 0.001). in vitro incubatio ...19873294836
[respiratory problems in patients with muscular dystrophy]. 20113285556
dose-dependent effects of oral and intravenous glucose on insulin secretion and clearance in normal humans.insulin secretion and clearance were studied in 2 groups of 7 normal subjects who each received 25, 50, and 100 g of glucose either orally or intravenously (iv) on separate occasions. insulin secretion rates were calculated during a 1-h base line and for 5 h after glucose administration from a two-compartmental analysis of peripheral c-peptide concentrations using individual kinetic parameters derived after iv bolus injections of biosynthetic human c-peptide. incremental glucose areas after oral ...19883279811
why not launch a new cadet nurse corps? 20103279779
supplemented schneider's drosophila medium for isolation of leishmania donovani promastigotes. 19883252764
[provisional crowns and bridges]. 19973250891
biotechnological applications of lipid microstructures. based on the proceedings of the workshop on technological applications of phospholipid bilayers, vesicles, and thin films, january 5-9, 1986, tenerife, canary islands; and the workshop on biotechnological applications of membrane studies, october 18-22, 1987, san sebastian, spain. 19883250236
vibrio alginolyticus cellulitis following coral injury.infections associated with marine activities, particularly work or recreation in salt water, present unique diagnostic challenges for the infectious disease practitioner. those caused by halophilic, non-cholera vibrio species are increasingly being recognized in clinical practice. they typically follow saltwater injuries, especially those associated with coral. because these infections can be both severe and life-threatening, a consideration of halophilic vibrio species in the differential diagn ...19883242316
synthesis and antineoplastic effects of furo[3,4-d]pyrimidine derivatives.furo[3,4-d]pyrimidine was obtained in the reaction of 2-phenyl-4-phenylamino-6-methyl-5-pyrimidinecarboxylic acid with socl2. this compound, heated with aliphatic amines, yielded mono- and diamino-derivatives. some of the obtained compounds exhibited a potent antineoplastic activity.20113237569
[kidney morphology in hemolytic-uremic syndrome].morphology of the kidneys in hemolytic-uremic syndrome is considered basing on autopsy findings obtained for 3 infants with 5-17-day history of acute renal failure. a newborn infant of 17 days developed the disease after feto-fetal hemotransfusion when macerated fetus-donor hemolysis products entered the circulation of the fetus-recipient through monochorionic placenta. the second case in an infant of 6 months was due to adtp vaccine. the last infant aged 16 months manifested the syndrome in the ...19883233069
individual free fatty acids and lactate uptake in the human heart during severe sepsis.coronary haemodynamics and myocardial metabolism of nonesterified fatty acids (nefa) and lactate were studied in 11 patients with severe sepsis, and compared to 10 control subjects. coronary sinus blood flow was evaluated by thermodilution. arterial and coronary sinus blood samples were collected for the measurement of lactate and total and individual nefa concentrations both in septic and control patients. there was an increase in lactate and total nefa arterial concentrations with a marked inc ...19883232957
[complications of catheter cerebral angiography]. 20113229240
[evaluation of the ventricular function using radioisotope ventriculography in patients with impaired glucose metabolism]. 20113228812
excision of cutaneous tumors in the horse using histologic guidance.a highly successful surgical technique for removing cutaneous tumors in humans was used in seven horses with cutaneous squamous cell carcinoma (n = 3) or sarcoid (n = 4). in humans, the complete underside of the tumor is evaluated histologically by processing horizontal sections from the tumor base, and orientation between the wound surface and the undersurface of the excised tumor is maintained by mapping both surfaces. the technique ensures that small foci of residual tumor can be located accu ...19883227634
[radiography of the nasopharynx and pharynx]. 20113225927
[local ultrastructural characteristics of the intracerebral arteries of human fetuses].in 36 human fetuses (16 to 36 weeks of gestation) the ultrastructure of arterial vessels was investigated in the occipital and parietal hemispheres and midbrain tegmentum. during the antenatal ontogenesis the local features of the vessel wall structure were found, especially in the muscular layer. as it remained more differentiated in midbrain than in forebrain up to the end of gestation, more frequent forebrain stroke localization in infancy seems structurally dependent.19883213332
[effects of stimulus modality and task instruction upon the orienting response].the purpose of this study is to confirm that habituated orienting response (or) is evoked when the visual and auditory stimuli are bimodally presented. in exp. i, either visual or auditory stimulus was exposed to 20 subjects in both habituation- and test-periods. in exp. ii, the visual and auditory stimuli were exposed conversely over the habituation- (either stimulus) and the test-periods (both stimuli). a half of the 20 subjects was instructed to pedal only when the test-stimulus was presented ...20113210459
ca2+ regulation of the thin filaments: biochemical mechanism and physiological role. 20113208977
the disposition of [2,3-14c]-methyl and [2,3-14c]-2-ethylhexyl acrylate in male wistar albino rats.the disposition of methyl [2,3-14c]-acrylate (ma) and 2-ethylhexyl [2,3-14c]-acrylate (eha) following intraperitoneal and oral administration to rats has been studied. the 14c found in the tissues was mainly associated with liver, kidneys and lungs. loss of 14c from these tissues occurred fairly rapidly, excluding the rats given eha intraperitoneally. most of the administered acrylates underwent rapid metabolism and excretion with expired air (more than 50% of the dose and urine (10-50% of the d ...19883196152
phlegmonous necrotising cellulitis after reduction mammoplasty. a report of 4 cases. 20113187790
helping the deaf in kenya. 20113187393
extensive deletions and insertions in different mhc supratypes detected by pusled field gel electrophoresis.the genomic organization of the human mhc was examined in multiple examples of six different supratypes using pulsed field electrophoresis (pfge) after digestion of genomic dna with infrequency cutting restriction endonucleases. differences in restriction fragment length and band intensity were shown to be specific for each supratype. mapping of the mhc revealed that each supratype contains previously undescribed deletions and insertions between hla b and dq regions.19883171479
metastatic adenocarcinoma of the carpus: a case report.a patient is described who presented with a painful swelling of the dorsum of the hand which arose from the hamate and proved histologically to be a secondary from a previously resected gastric adenocarcinoma.20113171299
roles of the respiratory na+ pump in bioenergetics of vibrio alginolyticus.bioenergetic characteristics of na+ pump-defective mutants of a marine bacterium vibrio alginolyticus were compared with those of the wild type and revertant. generation of membrane potential and motility at ph 8.5 in the mutants were completely inhibited by a proton conductor, carbonylcyanide m-chlorophenylhydrazone, whereas those in the wild type or revertant were resistant to the inhibitor. motility and amino acid transport were driven by the electrochemical potential of na+ not only in the w ...19883170506
nucleotide sequence of the regulatory gene xylr of the tol plasmid from pseudomonas putida.we have determined the nucleotide sequence of the xylr gene for a transcriptional activator for the degradative pathway of aromatic hydrocarbons on the tol plasmid from pseudomonas putida. the 1698-bp sequence for a 566-amino acid (aa) protein (mr 63741) was identified as the xylr-encoding sequence. three regions in xylr show homology to klebsiella pneumoniae ntrc and nifa, both of which are transcriptional activators for the ntr and nif genes involved in the nitrogen metabolism. the central reg ...19883169574
cleavage lines of the oral mucosa in japanese cadavers.cleavage lines were experimentally reproduced in the oral mucosa of japanese cadavers. they were investigated macroscopically and histologically. the reproduced cleavage lines showed little directional variation by sex or age. from the histological findings, the mucosal cleavage lines were interpreted to represent cleavage split along the direction of connective tissue fibres in the lamina propria.20113165386
structural and functional studies of the effects of sympathetic nerve stimulation on rabbit submandibular salivary glands.continuous sympathetic stimulation at 8-10 hz caused intense vasoconstriction in the gland, so stimulation was generally given in an interrupted pattern to minimize this detrimental effect on secretion. only a small increase in fluid secretion occurred; it became thick and tended to block the cannula; therefore in later experiments the main duct was not cannulated. after sympathetic stimulation there was substantial degranulation of acinar cells. however, as this was accompanied by little moveme ...19883165262
renal apical membrane cholesterol and fluidity in regulation of phosphate transport.renal proximal tubule cells adapt to dietary phosphate (pi) restriction by increasing pi transport independent of parathyroid hormone, vitamin d metabolites, or serum ca2+. to determine the underlying cellular mechanism(s), brush border (bbm) and basolateral membranes (blm) were isolated from growing male rats fed a synthetic diet containing variable levels of pi (0.1-1.4%). dietary pi restriction was without effect on either bbm or blm total lipid phosphorus, individual phospholipid species, or ...19853160247
a retrospective survey of asthma management in hospital.a retrospective survey of asthma admissions to general medical units during 1983 is described. 127 cases occurred, of whom 52 were males (44%). the average age was 45.2 years. forty-eight per cent were receiving inhaled steroids or cromoglycate before admission and 16% regular oral steroids. initial assessment seldom included peak flow measurement although these were made subsequently in 57%. no steroids were used in 32% of cases. no oxygen was given in 48% of cases and when used was usually at ...20113147510
effect of reperfusion on o2 supply/consumption balance in ischemic canine left ventricle.this study was designed to assess the effects of reperfusion on regional o2 supply and o2 consumption of ischemic areas of the myocardium in 15 anesthetized open-chested dogs. the left anterior descending coronary artery (lad) was occluded for 6 h (n = 8), 2 h (n = 5), 2-h occlusion followed by 4-h period of reperfusion (n = 7), and 10-min occlusion followed by 90-min period of reperfusion (n = 3). small artery and vein o2 saturations obtained microspectrophotometrically were combined with regio ...19883147502
[transperitoneal transport of methotrexate: in vitro studies]. 19883147495
prevention of respiratory distress syndrome.rds continues to be a major problem for premature infants despite a better understanding of its pathophysiology and of ways to try to prevent it. to date, prenatal administration of glucocorticoids has been the most widely used method of accelerating fetal lung development. however, several limitations of this therapy have prompted the search for alternative approaches. most efforts have focused on the potential use of combined hormonal therapy with glucocorticoids and either thyroid hormones or ...19883146813
a competitive enzyme-linked immunosorbent assay for alpha 1-acid glycoprotein in serum and urine samples.in this solid-phase competitive enzyme-linked immunosorbent assay for alpha 1-acid glycoprotein in serum or urine, antiserum to human alpha 1-acid glycoprotein is incubated with solid-phase-bound alpha 1-acid glycoprotein in the presence of standard or sample. incubation with second antibody labeled with alkaline phosphatase then follows, before development with substrate. results obtained correlate well with a fluorescent assay involving the dye auramine o (r = 0.953) and with radial immunodiff ...19883135959
biosynthesis of porphyrins and left ventricle function in patients with terminal renal insufficiency. 20113133291
bone mineral metabolism in experimental diabetes mellitus: osteocalcin as a measure of bone remodeling.the etiology of diabetic osteopenia has not been established. the value of serum osteocalcin (bgp) as a marker of the bone abnormalities and the possible role of the polyol pathway in diabetic osteopenia were investigated. three groups of rats were studied over 7 weeks: group d (n = 12), rats with streptozotocin (55 mg/kg)-induced diabetes given saline by gavage; group ds (n = 12), rats with streptozotocin-induced diabetes given the aldose reductase inhibitor sorbinil (25 mg/kg) daily by gavage; ...19883133194
valproate-associated hepatotoxicity and its biochemical mechanisms.intake of the anticonvulsant drug valproic acid, or its sodium salt, has been associated with occasional instances of severe and sometimes fatal hepatotoxicity. probably at least 80 cases have occurred worldwide. the syndrome affects perhaps 1 in 10,000 persons taking the drug, and usually develops in the early weeks or months of therapy. most instances have involved children, usually those receiving more than 1 anticonvulsant. multiple cases have occurred in 2 families. the typical presentation ...20113131628
cytopathic effects of the pathogenic neisseria. studies using human fallopian tube organ cultures and human nasopharyngeal organ cultures.infection of mucosal surfaces by n. gonorrhoeae and n. meningitidis may result in inflammation indicating potential injury to host cells. we used human fallopian tube organ cultures (ftoc) and human nasopharyngeal organ cultures (npoc) to study the mechanisms by which gonococci and meningococci damage human mucosal surfaces. early in the course of ftoc infected with gonococci and npoc infected with meningococci, damage was most apparent to ciliary activity. loss of ciliary activity was accompani ...19873130794
[enterostoma therapy--a pilot course in the essen education center of the german nursing association]. 20113127632
modification of arachidonic metabolism by flavonoids.the pharmacological effects of many plants depend on their flavonoid constituents. this review is concerned with the influence of flavonoids on arachidonic metabolism as the possible mechanism of action of such natural products. special attention has been paid to structure-activity relationships since this knowledge may allow the synthesis of more potent and selective analogs with therapeutic applications.20113126368
extracorporeal gas exchange in acute respiratory failure. 20113122975
deficiency of eosinophil peroxidase detected by automated cytochemistry. 20113122494
oesophageal pain exacerbated by propranolol. 20113113570
biosynthesis and processing of platelet gpiib-iiia in human megakaryocytes.platelet membrane glycoprotein iib-iiia forms a calcium-dependent heterodimer and constitutes the fibrinogen receptor on stimulated platelets. gpiib is a two-chain protein containing disulfide-linked alpha and beta subunits. gpiiia is a single chain protein. these proteins are synthesized in the bone marrow by megakaryocytes, but the study of their synthesis has been hampered by the difficulty in obtaining enriched population of megakaryocytes in large numbers. to examine the biosynthesis and pr ...19873108266
[antimicrobial susceptibility of vibrio parahaemolyticus and vibrio alginolyticus isolated from human feces and foods]. 19873106535
immunoelectrophoretic demonstration of rho(d) antigen of red blood cell membrane. 20113095572
annual summary 1984. reported morbidity and mortality in the united states. 20113092006
[development of a latex agglutination method for the diagnosis of pseudomonas aeruginosa infection].the present investigation has revealed the possibility of using different kinds of monodispersed polystyrene latex, produced in the ussr, as carriers in the process of the preparation of antibody diagnosticums intended for the detection of water-soluble slime antigens of pseudomonas aeruginosa strains belonging to the most widespread serological types. the optimum conditions for the preparation of latex reagents and for making the latex-agglutination test have been experimentally established. th ...19863087117
second-generation cephalosporins. 19863081544
[morphology of the kidneys in shock]. 20113078180
endothelium-dependent responses in human blood vessels. 19883073550
endothelium-dependent responses in human blood vessels. 19883073550
[use of methylumbelliferylglucuronide (mug) for the rapid identification of e. coli in food microbiology]. 19883072974
diphtheria toxin entry: protein translocation in the reverse direction. 20053072713
use of the romanian product silimarina in the treatment of chronic liver diseases.the romanian product silimarina (synonym legalon) was administered in a randomized double-blind trial, to a group of 180 patients with chronic persistent hepatitis (cph), chronic active hepatitis (cah) and hepatic cirrhosis (hc). the trial lasted for 40 days. the results showed favourable effects similar with those obtained with other preparations produced by foreign drug industries. the romanian product proved to have no toxic effect. the authors discuss the present possibilities of estimating ...20113072661
[the 35th anniversary of the independent existence of czechoslovak pharmacy schools]. 20113072093
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