Publications

delivered volume during high-frequency ventilation.		1989	2648741
complications of intracranial bypass for vertebrobasilar insufficiency.	the authors' initial experience with intracranial revascularization of vertebrobasilar insufficiency, reported previously, fortunately yielded reasonably good results with high patency rates but in some cases there were significant, albeit temporary, complications. since that time, major brain-stem strokes have occurred in two patients following superficial temporal to superior cerebellar artery bypass procedures. this occurrence has caused the authors to reassess their experience with this proc ...	2008	2643687
complications of intracranial bypass for vertebrobasilar insufficiency.	the authors' initial experience with intracranial revascularization of vertebrobasilar insufficiency, reported previously, fortunately yielded reasonably good results with high patency rates but in some cases there were significant, albeit temporary, complications. since that time, major brain-stem strokes have occurred in two patients following superficial temporal to superior cerebellar artery bypass procedures. this occurrence has caused the authors to reassess their experience with this proc ...	2008	2643687
methyl 2-[4-(2-chloroethyl)-2,3-dihydro-7-nitroquinoxalin-1-yl]benzoate from intramolecular cyclization of a nitroaromatic mustard.	c18h18cin3o4, mr = 375.81, orthorhombic, p212121, a = 11.000 (3), b = 8.023 (2), c = 19.316 (5) a, v = 1704.68 a3, z = 4, dm = 1.46 (1), dx = 1.417 g cm-3, mo kalpha, lambda = 0.71069 a, mu = 1.82 cm-1, f(000) = 760, t = 293 (1) k, r = 0.051 for 985 [i greater than 2.5 sigma(i)] reflections. x-ray analysis confirms that the nitroaromatic mustard methyl n-(2-[bis(2-chloroethyl)amino]- 5-nitrophenyl)anthranilate undergoes rapid intramolecular cyclization, but the product is the 7-nitro rather than ...	2008	2635608
non-germ cell testicular tumours in nigerians.	non-germ cell testicular tumours are reported to be more common in peoples of negroid and asian descent than in caucasians. this group of tumours comprised seven of sixteen testicular tumours seen in a ten-year period at the university of benin teaching hospital, benin city, nigeria. however, unlike experiences elsewhere in africa and the west indies where paratesticular tumours accounted for a majority of these tumours, malignant lymphomas constituted over 70% of non-germinal testicular tumours ...	2008	2635452
non-germ cell testicular tumours in nigerians.	non-germ cell testicular tumours are reported to be more common in peoples of negroid and asian descent than in caucasians. this group of tumours comprised seven of sixteen testicular tumours seen in a ten-year period at the university of benin teaching hospital, benin city, nigeria. however, unlike experiences elsewhere in africa and the west indies where paratesticular tumours accounted for a majority of these tumours, malignant lymphomas constituted over 70% of non-germinal testicular tumours ...	2008	2635452
calcium carbonate powder as a phosphate binder.	with increasing recognition of problems regarding the use of aluminum hydroxide as a phosphate binder, calcium carbonate has become the medication of choice. use of calcium has, however, frequently been associated with development of hypercalcemia. at this institution, calcium carbonate powder as a phosphate binder, examination of its efficacy, and the frequency of hypercalcemia with its use were of great interest. calcium carbonate powder (calcarb-hd, 2.4 gms elemental calcium/packet) (calcarb- ...	2006	2597473
enrolled nurses. we're backing the charter!		2008	2587373
comparative sequence analysis, in vitro expression and biosynthesis of mouse prp.	a number of studies have indicated that an endogenous brain protein, prp, is associated with transmissible agents causing spongiform encephalopathies such as scrapie, kuru, and creutzfeldt-jakob disease. it has been proposed that prp derived from scrapie brain is the scrapie agent itself. to test directly whether the prp mrna in scrapie brain tissue can encode the scrapie agent, we expressed prp cdna cloned from scrapie-infected mouse brain in vitro. the expressed prp did not transmit scrapie to ...	1989	2574873
glutamate degradation in the ischemic dog heart: contribution to anaerobic energy production.	the present study investigated the conversion of amino acids to succinate and the contribution of this pathway to anaerobic energy production during regional ischemia in the dog heart in situ. the relation between regional myocardial blood flow, estimated by the tracer microsphere technique, and myocardial contents of metabolites (glutamate, alanine, succinate, lactate) as well as their local arterio-venous differences (a-v) were determined. during 30 min of coronary artery occlusion, myocardial ...	1989	2565982
a double-blind trial of essential fatty acid supplementation in patients with tardive dyskinesia.	this study reports the results of a trial of essential fatty acid (efa) supplementation in psychiatric patients (predominantly schizophrenics) with movement disorders. evidence of efa deficiency in these patients was observed. the antidyskinetic effect of efa supplementation was marginally significant but not clinically important. however, active treatment produced highly significant improvements in total psychopathology scores and schizophrenia subscale scores, and a significant improvement in ...	2008	2565585
trends in screening mammograms for women 50 years of age and older--behavioral risk factor surveillance system, 1987.		2008	2493130
[experimental studies in the separation and identification of ingredients of the hexachlorocyclohexane ointment "antiscabiosum" (purity assessment)].		2008	2444036
whole-body autoradiography of [3h]dihydrostreptomycin in guinea pigs and rats: the labelling of the inner ear in relation to other tissues.	[3h]dihydrostreptomycin was given intramuscularly to young pigmented guinea pigs and rats. whole-body autoradiography, combined with densitometric measurement of the blackening of the autoradiograms, and liquid scintillation counting were used to determine the levels of radioactivity in the inner ear in relation to blood and other tissues. it was found that there was an accumulation of radioactivity in the perilymph of both the cochlear and vestibular parts of the labyrinth. the labelling of the ...	1986	2422870
toxicology of selected pesticides, drugs, and chemicals. organophosphorus and carbamate insecticides.	organophosphorus and carbamate insecticides produce acute toxicosis via a common mechanism--the inhibition of acetylcholinesterase--and, therefore, these categories of insecticides are considered together. this article discusses the mechanisms, toxicity, clinical signs, lesions, and diagnosis of, as well as treatment for, toxicoses produced by these compounds.	1990	2180181
production of enterotoxin and cytotoxin by aeromonas veronii.	fourteen strains of aeromonas veronii were isolated from salt and fresh water in rio de janeiro and investigated for the presence of virulence factors. eleven (79%) a. veronii strains were positive for enterotoxin by the suckling-mouse test and thirteen (93%) produced hemolysin. of the 13 a. veronii strains that produced hemolysin, seven were investigated for cytotoxin production using vero cells as indicator cells and all of them were positive.	1990	2095293
fournier's gangrene.	fournier's gangrene or synergistic gengrene of scrotum and penis is a relatively rare but serious condition which can occur in any general or hospital practice. early diagnosis with prompt aggressive treatment including antibiotics and surgical debridement are necessary to achieve patient survival. we report our clinical experience with three cases which occurred in three different hospitals in the irish republic. in two of these cases diabetes mellitus was an important predisposing factor. all ...	2007	2045267
epidemiological surveys of senile dementia in japan.	epidemiological surveys of senile dementia at home were carried out on 3,754 subjects for two consecutive years, 1987 and 1988. the prevalence and incidence rates were 4.1% and 1.01%, respectively. concerning the incidence rate, the sample populations of previous reports were small in number--less than 1,000. if we suppose that the incidence were to be approximately 1%, then it follows that dementia would be noted yearly in no more than one out of 100 senile subjects. a difference in subject num ...	2007	2045242
dna adducts in bronchial biopsies.	to investigate the feasibility of measuring dna-carcinogen adducts in the lungs of non-surgical patients, endobronchial biopsies were obtained from 78 patients undergoing routine diagnostic bronchoscopy. lung cancer was present in 37 (47%) of the patients. dna was isolated from the tissues and analyzed by hplc- or nuclease-pi-enriched 32p-postlabelling, using procedures selective for aromatic adducts. chromatograms from all 28 current smokers showed a distinctive diagonal adduct zone which was p ...	2007	2045196
aeromonas jandaei and aeromonas veronii dual infection of a human wound following aquatic exposure.	exudate removed from an infection that developed below the left eye of a 10-year-old male following a previously inflicted wound after aquatic exposure was cultured and revealed two different aeromonas spp. further characterization showed that one strain was phenotypically identical to aeromonas veronii, while the other strain was confirmed by dna hybridization analysis to be aeromonas jandaei sp. nov. this is the first report of these more recently described aeromonads, thus far rarely reported ...	1991	2037674
biochemical and genetic characterization of autoagglutinating phenotypes of aeromonas species associated with invasive and noninvasive disease.	the genetic characteristics and biochemical and structural properties of a number of autoagglutinating (aa) strains of aeromonas associated with invasive and noninvasive disease in humans and infections in animals and from environmental sources were investigated. of 27 strains analyzed by multilocus enzyme typing and dna hybridization studies, 25 (93%) were confirmed to belong to either hybridization group 1 (phenospecies and genospecies aeromonas hydrophila) or 8 (phenospecies aeromonas sobria; ...	1991	2010642
conservative surgery and radiation therapy for early stage breast cancer. can large trial experiences be reproduced in a community hospital setting?	conservative surgery and radiation therapy were used to treat 212 patients with ajc clinical stage i or ii breast carcinoma at the baptist hospital of miami. all had lumpectomy and most axillary lymph node dissection, followed by breast irradiation to a dose of 45 gy and a boost dose of 14 to 16 gy to the surgical bed. median follow-up was 55 months. the five-year actuarial local control and survival rates were 94% and 86% respectively. eighty-six percent of the patients had excellent or good co ...	2007	1963436
gas-liquid chromatographic analysis of cellular fatty acid methyl esters in aeromonas species.	the cellular fatty acids of 39 strains belonging to the genus aeromonas (aeromonas hydrophila, aeromonas caviae, aeromonas sobria, aeromonas media, aeromonas schubertii, aeromonas veronii) were determined by high resolution gas-liquid chromatography. the fatty acid profiles were characterized by major amounts (60% or more) of one saturated (hexadecanoic acid = 16:0) and two unsaturated (hexadecenoic acid = 16:1 and octadecenoic acid = 18:1) acids. while the majority of the strains of the six spe ...	1991	1930556
[a method of administration of drugs into the small joints of the hand and foot].		2007	1925267
does prestretching stainless-steel wire have any clinical significance?	clinical parameters of prestretch and tension forces placed on stainless-steel wire by 20 oral and maxillofacial surgeons were obtained. unstretched wire was clinically as tough or tougher than prestretched wire of a similar gauge. both prestretched and unstretched wires, twisted to their maximum, loosened when under tension. as the prestretch forces increased, the clinical strength of the wire diminished.	2007	1890520
fixed drug eruption due to pipemidic acid.	a 71-year-old woman with fixed drug eruption caused by pipemidic acid is reported. the patient developed typical lesions on rechallenge with pipemidic acid, but not with nalidixic acid, an analogue of pipemidic acid.	2007	1828818
retinal neurite growth on astrocytes is not modified by extracellular matrix, anti-l1 antibody, or oligodendrocytes.	two factors that may influence the course of axonal regeneration in the central nervous system (cns) are extracellular matrix (ecm) and cell surface molecules that may enhance or inhibit neurite outgrowth. whereas cultured astrocytes have been reported to be a good substratum for neurite outgrowth, there is recent evidence that cultured oligodendrocytes are inhibitory. to test the influences of 1) ecm components, 2) the l1 adhesion molecule, and 3) the inhibitory potential of mature oligodendroc ...	1991	1828788
[photic maculopathy by low energy laser beam. a case report].	the authors report a case of photic maculopathy that developed in a 30-year-old laboratory worker after repeated, consecutive exposure to low energy he-ne laser. pigmented foveal change and a small central scotoma in the right eye with window defect on fluorescein angiography characterized this maculopathy. photochemical damage is considered to be the cause of the maculopathy.	2006	1797372
[photic maculopathy by low energy laser beam. a case report].	the authors report a case of photic maculopathy that developed in a 30-year-old laboratory worker after repeated, consecutive exposure to low energy he-ne laser. pigmented foveal change and a small central scotoma in the right eye with window defect on fluorescein angiography characterized this maculopathy. photochemical damage is considered to be the cause of the maculopathy.	2006	1797372
changes in body composition and energy expenditure after six weeks' growth hormone treatment.		2006	1796983
changes in body composition and energy expenditure after six weeks' growth hormone treatment.		2006	1796983
[the effect of antibiotics on the intestinal flora].		2006	1762418
effects of converting-enzyme inhibition on barrier function in diabetic glomerulopathy.	differential solute clearances were used to examine the effects of a 90-day course of enalapril on glomerular barrier function in 16 proteinuric patients with diabetic glomerulopathy. by day 90, plasma renin and prorenin became elevated, and arterial pressure declined. transglomerular passage of dextrans of broad size distribution (radii 28-60 a) was lowered significantly. in a subset of 8 patients, withdrawal of enalapril was followed after an additional 30 days by a return of renin levels and ...	2006	1698674
effects of converting-enzyme inhibition on barrier function in diabetic glomerulopathy.	differential solute clearances were used to examine the effects of a 90-day course of enalapril on glomerular barrier function in 16 proteinuric patients with diabetic glomerulopathy. by day 90, plasma renin and prorenin became elevated, and arterial pressure declined. transglomerular passage of dextrans of broad size distribution (radii 28-60 a) was lowered significantly. in a subset of 8 patients, withdrawal of enalapril was followed after an additional 30 days by a return of renin levels and ...	2006	1698674
monoclonal antibodies to quebec strain (q17) of bovine rotavirus.	fourteen monoclonal antibodies (mabs) against "quebec" strain (q17) of bovine rotavirus were isolated and characterized. four were specific for viral protein vp7 and ten were specific for viral protein vp6. five different isotypes were represented by this group of antibodies. all of the anti-vp6 and none of the anti-vp7 antibodies were sensitive to the effects of periodate on their antigen. the antibodies could be separated into three groups based on their relative resistance to the dissociation ...	1990	1698323
developmental cycle-specific host-free rna synthesis in chlamydia spp.	the incorporation of radiolabeled gtp into rna in host-free chlamydia trachomatis serovar l2 organisms was investigated. the incorporation was partially inhibited by rifampin and dactinomycin and hydrolyzed by rnase. rna made by host-free chlamydiae consisted mainly of species of fewer than 800 bases in size, although 16s and 23s species were noted by agarose-gel electrophoresis. the hybridization of radiolabeled host-free rna to restriction fragments of the gene encoding the major outer membran ...	1990	1698176
glycosidase activities in gingival crevicular fluid in subjects with adult periodontitis or gingivitis.	specific glycosidase activities were determined in samples of gingival crevicular fluid (gcf) collected from eight predetermined sites in two groups, each of 20 adult patients, with either gingivitis or periodontitis. the total activities (as units of enzyme activity per sample) of alpha-l-fucosidase, sialidase, beta-n-acetylglucosaminidase, beta-galactosidase, beta-glucosidase and alpha-glucosidase were significantly greater in the periodontitis group. in contrast, the total beta-mannosidase an ...	2006	1610303
[body packing as a fatal risk--results of a questionnaire survey in western europe].	a questionnaire was sent to 138 institutes of forensic medicine in 18 countries of western europe to obtain information concerning bodypackers, who had died between 1980 and 1990. the total number of dead was 17 (4 own cases). 8 cases were reported from the federal republic of germany, 4 from italy, 2 from great britain and 1 from austria, spain and norway each. in 15 cases some circumstances were told. most of the bodypackers had transported heroin (10), in 2 cases cocaine and amphetamine were ...	2006	1489327
haemorheology and exercise: intrinsic flow properties of blood in marathon running.	haemorheological and haematological parameters were studied in venous blood samples taken from 8 endurance-trained athletes before and after a marathon run. viscometry was performed in a 20 microns glass capillary and in a couette viscometer. apparent blood viscosity was lower in the capillary than in the rotational viscometer, but significant differences between pre- and post-run samples were not observed in either system. this is presumably due to the absence of changes of haematocrit (pre-run ...	2006	1459744
thermally-induced delayed fluorescence of photosystem i and ii chlorophyll in thermophilic cyanobacterium synechococcus elongatus.	stationary delayed fluorescence (df) of chlorophyll in isolated membrane preparations from thermophilic cyanobacterium synechococcus elongatus was investigated as a function of temperature. two peaks at different temperatures were observed. the low-temperature peak (54-60 degrees c) coincided with the main maximum of the thermally-induced delayed fluorescence of chlorophyll in intact cells and psii-particles with active oxygen-evolving system. the high-temperature peak (78 degrees c) coincided w ...	1992	1426973
changes in drug treatment after discharge from hospital in geriatric patients.	to ascertain changes in drug treatment of elderly patients after discharge from hospital and to identify areas of communication which may require improvement.	2006	1393119
health checks on patients 75 years and over in nottinghamshire after the new gp contract.	to investigate annual health checks for patients of 75 years and over required by the 1990 contract for general practitioners.	2006	1393076
halogenated isoniazid derivatives as possible antitubercular and antineoplastic agents. note 1.	halogenated arylhydrazones, 2-aryl-4-thiazolidinones and their 1,1-dioxides containing isoniazid (ini) moieties were prepared and explored for antimicrobial (against bacteria, candida and mycobacteria) and antitumor activities. none of the tested compounds showed any marked antimicrobial effect. furthermore, among the compounds submitted to nci in vitro primary antitumor screening, those bearing 3-fluoro or -chlorophenyl substituents were found to possess selective inhibitory effects on the grow ...	1992	1388607
immunochemical analysis and possible biological role of an aeromonas hydrophila surface array protein in septicaemia.	the biochemical, immunological, and biological properties of an s layer purified from an aeromonas hydrophila strain (ah-342) involved in a case of bacteraemia were investigated. the s layer selectively removed from the cell surface was composed of a single acidic (pi 4.56) protein subunit (surface array protein, sap) with a molecular mass of approximately 52 kda. amino acid analysis of this 52 kda protein indicated a molecule composed of 498 amino acids with 46% hydrophobic residues. no cystein ...	1992	1382113
antigenic diversity of the s-layer proteins from pathogenic strains of aeromonas hydrophila and aeromonas veronii biotype sobria.	the antigenic relatedness of paracrystalline surface array proteins with subunit molecular weights of approximately 52,000 from isolates of aeromonas hydrophila and aeromonas veronii biotype sobria belonging to a single heat-stable serogroup was examined. enzyme-linked immunosorbent assay and immunoblotting with two different polyclonal antisera against surface exposed and non-surface-exposed epitopes of the s-layer protein from a. hydrophila tf7 showed that the s-layer proteins of the mesophili ...	1992	1370287
[h2-receptor antagonist-refractory ulcer--its pathophysiology and role of proton-pump inhibitors].	among h2-receptor antagonist (h2ra)-refractory ulcers, non-responders that did not heal after 5 months therapy had high intraluminal ph in the basal condition and high sensitivity to inhibition of acid secretion by h2ra but possessed gastric mucosa to generate less prostaglandins. combination therapy of pge1-analogue with h2ra healed these ulcers by 60%. proton-pump inhibitor (ppi) exerted a complete inhibition of acid secretion in these patients and the rate of healing was 88%. helicobacter pyl ...	1992	1347325
5-hydroxytryptamine receptor activity of the dopamine receptor agonist fenoldopam in canine tracheal smooth muscle.	fenoldopam is a new vasodilator undergoing clinical trials for the treatment of hypertensive emergencies. its pharmacologic effects result from activation of vascular dopamine-1 receptors. in canine tracheal smooth muscle strips, fenoldopam caused a concentration- and calcium-dependent increase in tension, which was not antagonized by atropine, indomethacin or the dopamine-1 receptor antagonist, sch 23390. the ec50 (1.89 x 10(-6) m) exceeded that of serotonin or acetylcholine (8.38 x 10(-8) and ...	1992	1346635
the chemical use, abuse, and dependence scale (cuad). rationale, reliability, and validity.	this article describes the rationale for the development of the chemical use, abuse, and dependence scale (cuad). the instrument is in a semistructured interview format; it derives both substance use severity scores and dsm-iii-r substance use disorder diagnoses and can be administered in a short period with minimal training. the reliability and validity of the cuad are reported and appear satisfactory. the cuad is recommended for use as a detection, diagnostic, and treatment selection index in ...	2005	1317464
[a strain of aeromonas veronii isolated from a patient suspected of cholera].	investigations were carried on a strain isolated from patient hospitalized in poland. the patient returned from odessa, a region with cholera epidemic. the strain was suspected to be vibrio cholerae, but it did not agglutinate in v. cholerae 01 serum. the aim of this study was establishment of taxonomical classification of this strain, in order to demonstrate whether it is a representative of the non-cholera vibrio group (not agglutinating) or another representative of the family vibrionaceae. t ...	1992	1297030
[personality of patients with myocardial infarct].		2005	1236645
[changes in the composition of intracellular lipids and hydrocarbons in candida tropicalis in the absence of growth].	the fatty acid composition of lipids and the composition of hydrocarbons were studied in candida tropicalis cultivated on a medium with propionic acid and incubated in the conditions of starvation and on a medium containing glucose-1-6-14c but no nitrogen. intracellular fatty acids with an odd number of carbon atoms were found to be easily metabolized by yeast cells. the content and composition of intracellular hydrocarbons were very labile and underwent intensive transformation caused by change ...	1975	1214607
male transsexualism in england: sixteen cases with surgical intervention.	the syndrome of transsexualism is now regarded as a dinstinct entity separate from transvestism and homosexuality (benjamin, 1966; green and money, 1969). it refers to those patients who since childhood have been convinced of their wrong sex assignment and who wish to attain the sexual characteristics of the opposite sex and to live as a member of that sex. the present report is an initial one referring to the first group of transsexual patients studied at a postgraduate teaching hospital by a m ...	2005	1169047
geriatric patient care. opinions of a sample of nurses.		2005	1134987
the differentiation of cytotoxic t lymphocytes in vitro: an ultrastructural study.	t killer cells were identified morphologically in two different culture systems. the first system allowed identification by comparing under identical culture conditions two types of stimulation, one leading to cytotoxic activity levels that were very high (h-2 stimulation) and the other to levels which were practically nil (m-locus stimulation). a second system allowed identification by the use of a collaborative system in which relatively pure precursors of t killer cells were mixed with precur ...	2005	1082798
[surgical sciatica. study of 251 cases undergoing a single operation (author's transl)].		2005	544204
serially etched shark enameloid observed by incident light microscopy.	longitudinal and transverse tooth sections of isurus oxyrinchus were serially etched in 2.6% nitric acid. the changing optical properties of the etched surfaces were observed during the serial etchings, and the descent of the enameloid surfaces was measured. shark enameloid seems to be less effectively etched by acid than human enamel; this difference may be due to differences in solubility between fluorapatite and hydroxyapatite. most of the information regarding the structure of the enameloid ...	1979	525241
analysis of the antagonistic effect of gamma-l-glutamyl-taurine on glucocorticoid and triiodothyronine.	gamma-l-glutamyl-taurine, a newly discovered parathyroid hormone, considerably inhibited the cytochemically detected transcription-inducing effect (appearance of free histone) of prednisolone and triiodothyronine. such an inhibition took place also if the morphogenetic hormones were given not simultaneously with, but after the administration of litoralon. litoralon injected alone also displayed inductor properties increasing the number of nuclei containing free histone.	1979	525237
cp-20,961: a structurally novel, synthetic adjuvant.		1979	522084
[bilirubin in the blood serum of clinically healthy cows and those ill with ketosis and hepatopathies].	studied was the bilirubin equilibrium in 62 normal cows, 52 cows with clinical ketosis, 31 cows with diffuse liver injury, and 14 cows that went off food for five days. a moderate rise of the total bilirubin of mixed type was found in ketosis-affected cows. statistically significant proved the changes in the free fraction, however, there were no persuasive data that they were due to superproduction of bilirubin. changes in the total bilirubin similar to those in cows with ketosis were establishe ...	1979	516442
effect of high-energy feedings on low birthweight infants.	a comparison of the effect of 100.5 kj/30 ml (24 kcal/30 ml) feedings with that of 84 kj/30 ml (20 kcal/30 ml) feedings on infants with a birthweight of 1500 g or less was made. no consistent benefits in growth occurred and there was a tendency for an increase in complications in infants fed the 100.5 kj/30 ml milk. hence the higher-energy feeding cannot be recommended as the routine feeding for low birthweight infants.	2004	470692
children's literature on death and dying.		2004	375165
reduction of microbial contamination from ultrasonic scalers.		2004	356863
preparation of acid-fast microscopy smears for proficiency testing and quality control.	a method is presented for preparing smears for proficiency testing and quality control in acid-fast microscopy. the work was prompted by the increased demand for acid-fast bacilli positive smears with characteristic microscopic appearance and among-smear uniformity.	1978	353070
chromosome banding patterns of 49 cases of chronic myelocytic leukemia.		1977	266114
constant and variable regions in glycoprotein hormone beta subunit sequences: implications for receptor binding specificity.		1994	201763
conformational energy calculations for dinucleotide molecules. a systematic study of dinucleotide conformation, with application to diadenosine pyrophosphate.		1995	177120
demonstration of oncogenic potential of mammalian cells transformed by dna-containing viruses following photodynamic inactivation.	the oncogenic properties of hamster embryo cells transformed by herpes simplex virus type 1 (hsv-1) and type 2 (hsv-2) and sv40 virus following photodynamic inactivation using neutral red were determined by subcutaneous inoculation into newborn syrian hamsters. cells transformed by all three viruses produced palpable tumors after different latent periods. histopathological examination showed that hsv-2 tumors were fibrosarcomas and metastases were often seen in the lungs. hsv-2 primary tumors we ...	1975	165153
transformation of horse skin cells by type-c sarcoma viruses.	a horse skin cell line (e. derm, nbl-6, ccl-57) was susceptible to focus formation by the kirsten mouse sarcoma virus, feline sarcoma virus (st stain) and the msv pseudotypes with woolly monkey, gibbon monkey, rd-114, at-124, baboon placenta and murine xenotropic (balb/c 3t3 and c57l/jd) type-c viruses. foci were detected within 5 days after infection and the transformed cells continued to produce infectious virus and group-specific antigen of their respective type-c leukemia viruses. the transf ...	1975	165152
factors influencing prognosis after myocardial infarction.		2003	161872
pelvic displacement of a cardiac pacemaker following trauma. a case report.	the rate migration of an implanted cardiac pacemaker from the subrectus area anterior to the peritoneum to the pelvis following a motor vehicle accident is reported. discovery of dislodgement was made by observing a marked increase of pacemaker impulse amplitude in the three standard limb leads as measured on an oscilloscope.	2003	152472
k+, mg2+-aspartate (kmg-asp)--mediated prevention of isoproterenol(iso)-induced metabolic changes in the myocardium.	isoproterenol (iso) in a single dose of 7.5 mg/kg b.w. i.v was found to produce alterations of cardiac metabolism in dogs. after 2 h, high energy phosphate stores and glycogen were reduced, whereas the levels of lactate, pyruvate, the lactate/pyruvate ratio and myofibrillar atpase activity were elevated. ca2+ -accumulation by sarcoplasmic reticulum (sr) and mitochondria were increased (p less than 0.01). after 24 h, a partial recovery in the parameters followed could be observed. only myofibrill ...	1975	126687
[dental findings in children with hearing disorders].	tooth findings are reported of 972 children aged between 3 to 18 years who suffer from impaired hearing. logopedic pupils had significantly more tooth anomalies than those with impaired and normal hearing. the deaf pupils had significantly less dysgnathias than others with impaired hearing. as compared to those with normal hearing there was no significant difference.	2002	124119
[evolution and transformation in animal organism of some polychlorobiphenyls (author's transl)].	intoxication by pure polychlorobiphenyls and a commercial product is studied, in rats, after intraperitoneal and oral administration. their fixation and excretion of their metabolites is greater by intraperitoneal than by oral administration. the only hydroxy metabolites, identified by means of synthesis, gas chromatography and mass spectrometry are, all, derivatives from trichlorobiphenyl. it appears that administration of commercial product induces a more rapid degradation of these compounds i ...	1978	105430
health expenditure 1978/79.		1998	104698
clinical studies on pipemidic acid.		1978	101691
family life cycle resource center in the elementary school.		2001	98495
long term effects of myochrysine in articular cartilage.	intra-articularly administered sodium aurothiomalate (myochrysine) produced aurosomes containing characteristic electron dense contents (indicating the presence of gold), in the chondrocytes of rabbit articular cartilage. at first the aurosomes were bounded by a membrane but later the electron dense contents were seen lying free in the cytoplasmic matrix. such deposits were detectable up to 14 months after injection of myochrysine but none were found at later time intervals (18 months and 2 year ...	1978	97856
cellular changes in the toad urinary bladder in response to metabolic acidosis.	the urinary bladder of bufo marinus excretes h+ and nh+4, and the h+ excretion is increased when the animal is placed in metabolic acidosis. the mitochondria-rich (mr) cells mediate the h+ excretion by the bladder. the purpose of this study was to determine if there is a change in mr cells of the bladder during metabolic acidosis. bladders from normal toads and from toads that had been placed in metabolic acidosis were used. the bladders were mounted between plastic chambers and h+ excretion mea ...	1999	96269
normal immunosuppressive protein: in vitro inhibition of dna synthesis in t and b lymphocytes and lymphoid cell lines.	the biologic activity of normal immunosuppressive protein (nip) isolated from human plasma was studied. nip was found to inhibit the proliferation of both t and b lympohcytes in vitro. it suppressed the dna synthesis of normal mouse lymphocytes responding to the mitogens phytohemagglutinin and lipopolysaccharide, as well as the [3h]thymidine and [3h]leucine uptake by t and b lymphoid cell lines of human and murine origin. the lymphoid specificity of nip was demonstrated by showing that dna and p ...	1979	93092
specificity and t-lymphocyte dependence of the humoral immune response in the rat to purified ovine and porcine mucins.		1979	92759
[overview of the history of ceramics instead of a preamble].		2001	90452
detection by antihapten antibodies of liver-bound compounds related to azocarcinogens or their metabolites.	the localization of known azocarcinogens and metabolites such as p-aminoazobenzene and n-methyl-p-aminoazobenzene bound to components of liver cells of rats fed single or multiple doses of 3'-methyl-p-dimethylaminoazobenzene has been determined with the use of antibodies raised against p'-azo-p-aminoazobenzene and p'-azo-n-monomethyl-p-aminoazobenzene in the indirect fluorescent antibody procedure. these 2 antisera reacted with liver cells of rats fed 3'-methyl-p-dimethylaminoazobenzene, p'-amin ...	1979	90352
a new method for degradation of the protein part of glycoproteins: isolation of the carbohydrate chains of asialofetuin.	a new method has been developed for degrading the protein part of several glycoproteins, whilst leaving the carbohydrate portion virtually intact apart from partial degradation at the reducing end. the method is based upon stabilization of the glycosidic linkages of the sugar residues by trifluoroacetyl groups and subsequent cleavage of the peptide bonds by transamidation. the two reactions are carried out in a mixture of trifluoroacetic anhydride and trifluoroacetic acid. after o- and n-detrifl ...	2000	89909
cytotoxic macrophages induced in hamsters by vaccinia virus: selective cytotoxicity for virus-infected targets by macrophages collected late after immunization.		1979	87476
immunologic features of a carcinogen-induced murine bladder cancer: in vivo and in vitro studies.	certain in vivo and in vitro immunologic features of carcinogen-induced murine bladder cancer have been studied. the consistency of tumor induction, its natural history, and immunogenicity both in vivo and in vitro render this syngeneic murine bladder tumor a suitable model for immunologic studies. pre-immunization of strain c3h/hen mice with mid-gestational fetal cells did not protect the animals from tumor challenge. sera of mice immunized with mid-gestational fetal cells were not cytotoxic to ...	2000	86659
observations on the m-wave and the cnv in the squirrel monkey.	a typical cnv paradigm, with food as reward, evokes in the squirrel monkey's post-arcuate and post-central cortices both m-waves in response to the cues and what appears to be a cnv in the interstimulus interval. both wave forms appear to be generated locally in cortex and to be more closely related temporally to the cues than to the animal's behavioral response. the cnv, like the m-wave, appears to reflect the animal's level of interest in obtaining the reward. it is smaller when the animal mis ...	1979	85525
mechanism of action of beta-blockers in hypertension.		2001	14643