| physicochemical and biological properties of an extracellular serine protease of aeromonas sobria. | previously, we cloned a protease gene of aeromonas sobria, determined its nucleotide sequence and established a method of purifying its product. in this study, we examined the properties of the purified protease. the protease was temperature-labile and had an optimal ph of 7.5. metallo-protease inhibitors and a cysteine protease inhibitor did not block the proteolytic activity of the enzyme. the treatment with reagents to modify sulfhydryl group did not reduce the activity. but, serine protease ... | 2002 | 12153115 |
| clinical presentations, prognostic factors, and mortality in patients with aeromonas sobria complex bacteremia in a teaching hospital: a 5-year experience. | bacteremia due to aeromonas sobria complex is an uncommon clinical presentation, associated with a high mortality rate. this retrospective study reviewed the clinical manifestations and prognostic factors of a. sobria complex bacteremia. | 2009 | 20422137 |
| lipase activity and gene cloning of acinetobacter calcoaceticus lp009. | the production of lipase from acinetobacter calcoaceticus lp009, a bacterium isolated from raw milk, was found to be best induced by tween-80 at 1.0% concentration. it was efficiently secreted, and only a minute amount of activity was detected at the cell surface and intracellularly. a. calcoaceticus lp009 lipase exhibited maximum activity at ph 7.0 and 50 degrees c, and was relatively stable upon storage at ph 5.0 to 7.0 and at 4, 30, or 37 degrees c. the enzyme was found to be inactivated by e ... | 1998 | 12501281 |
| liver abscess and aeromonas bacteremia with septic pulmonary embolism. | a 68-year-old healthy man was admitted because of liver abscess and aeromonas bacteremia accompanied by pulmonary embolism. aeromonas sobria was isolated from blood. coagulation parameters were normal and a lower limb venogram showed no evidence of thrombosis. septic embolism originating from the liver abscess was considered as the possible cause of pulmonary embolism. the patient was successfully treated with antibiotics. | 2003 | 14606725 |
| simple and direct detection of aeromonas hydrophila infection in the goldfish, carassius auratus (l.), by dot blotting using specific monoclonal antibodies. | a combination of eight isolates of aeromonas hydrophila was used to produce monoclonal antibodies (mabs). ten different groups of mabs specific to aeromonas were selected. the first five groups of mabs demonstrated high specificity and bound to only one or two isolates of a. hydrophila. the sixth and the seventh groups of mabs were a. hydrophila specific. they recognized seven of eight a. hydrophila isolates (ah1, 2, 3, 4, 5, 6, 8); however, the mab in the seventh group also showed cross-reactiv ... | 2010 | 21091724 |
| microbial transformation of pyrethroid insecticides in aqueous and sediment phases. | recent studies showed that synthetic pyrethroids (sps) can move via surface runoff into aquatic systems. fifty-six of sp-degrading bacteria strains were isolated from contaminated sediments, of which six were evaluated for their ability to transform bifenthrin and permethrin in the aqueous phase and bifenthrin in the sediment phase. in the aqueous phase, bifenthrin was rapidly degraded by strains of stenotrophomonas acidaminiphila, and the half-life (t1/2) was reduced from >700 h to 30 to 131 h. ... | 2004 | 14768859 |
| enhancement of protective immunity in european eel (anguilla anguilla) against aeromonas hydrophila and aeromonas sobria by a recombinant aeromonas outer membrane protein. | to develop a vaccine, which can simultaneously prevent the diseases caused by various pathogenic bacteria in fish, we try to find a conserved outer membrane protein (omp) antigen from different bacterial pathogens. in this study, an omp fragment of 747 bp (named as omp-g), which was highly conserved in seven aeromonas omp sequences from the ncbi database, was amplified by pcr from one aeromonas sobria strain (b10) and two aeromonas hydrophila strains (b27 and b33) with the designed specific prim ... | 2010 | 21148192 |
| an outbreak of hospital acquired diarrhea due to aeromonas sobria. | six children admitted in a 18 bedded hematology-oncology unit, developed acute diarrhea in a four week period between march and april 2001. salmonella senftenberg was the additional pathogen in the stool sample of one patient who developed cola colored urine and pneumonia in the course of his illness. all the aeromonas strains had a similar biotype and antibiogram. the diarrhea subsided spontaneously in two children whilst three responded to antimicrobial therapy. one patient sought discharge an ... | 2004 | 15475633 |
| the influence of environmental bacteria in freshwater stingray wound-healing. | invasion by bacteria can influence the course of healing of wounds acquired in aquatic environment. in this study, the bacteria present in potamotrygonmotoro stingray mucus and in the alto paraná river water were identified, and their ability to induce tissue injury and resist antibiotics was determined. biochemical identification analysis showed that 97% of all bacterial isolates were gram negative, aeromonas spp., enterobacter cloacae and citrobacter freundii being the species most prevalent. ... | 2011 | 21635911 |
| three goose-type lysozymes in the gastropod oncomelania hupensis: cdna sequences and lytic activity of recombinant proteins. | three goose-type (g-type) lysozymes, designated as ohlysg1, ohlysg2 and ohlysg3 were identified from expressed sequence tags (ests) of a gastropod oncomelania hupensis, the intermediate host of schistosoma japonicum. the full cdna sequences of ohlysg1, ohlysg2 and ohlysg3 consisted of 735, 909 and 808 nucleotides, with an open reading frame of 198, 214 and 249 codons containing a 21, 7 and 8 amino acid (aa) signal peptide at the n-terminus, respectively. the three g-type lysozymes shared conserv ... | 2011 | 21756934 |
| [preparation and identification of ompw monoclonal antibodies]. | to prepare and characterize the mouse monoclonal antibodies against vibrio parahaemolyticus ompw. | 2011 | 21906472 |
| Structural and Functional Analysis of the Serine Protease from Aeromonas sobria. | Aeromonas species are Gram-negative facultative anaerobic bacteria found ubiquitously in a variety of aquatic environments and most commonly implicated as causative agents of gastroenteritis. Sepsis is a fatal complication of Aeromonas infectious diseases, particularly in immune-compromised patients. Two species, Aeromonas hydrophila and Aeromonas sobria, are associated with human disease. Feasible virulence factors of Aeromonas include fimbrial and afimbrial adhesion molecules, hemolysins, ente ... | 2011 | 22129876 |
| a pore-forming toxin produced by aeromonas sobria activates camp-dependent cl- secretory pathways to cause diarrhea. | aeromonas sobria hemolysin (ash) is one of the major virulence factors produced by a. sobria, a human pathogen that causes diarrhea. we investigated the effects of ash on cl(-) transport in human colonic epithelial cells. ash increased short-circuit currents (isc) and (125)i efflux from caco-2 cells, indicating ash activate cl(-) secretion. additions of inhibitors of cyclic amp dependent cl(-) channels, glybenclamide and nppb suppressed the isc and (125)i efflux increases induced by ash. and ash ... | 2005 | 15621437 |
| a pore-forming toxin produced by aeromonas sobria activates ca2+ dependent cl- secretion. | bacteria produce many types of hemolysin that induce diarrhea by mechanisms that are not completely understood. aeromonas sobria hemolysin (ash) is a major virulence factor produced by a. sobria, a human pathogen that causes diarrhea. since epithelial cells in the intestine are the primary targets of hemolysin, we investigated the effects of ash on ion transport in human colonic epithelial (caco-2) cells. ash increased short-circuit currents (isc) in a dose-dependent manner, and it also activate ... | 2005 | 15797812 |
| cerebral perfusion pressure: a hemodynamic mechanism of mannitol and the postmannitol hemogram. | sixteen patients each received infusions of 1 g of mannitol per kg over 5 to 10 minutes, and serial determinations of intracranial pressure (icp), systemic arterial blood pressure (sabp), central venous pressure, cerebral perfusion pressure (cpp), hematocrit, hemoglobin, serum na+, k+, osmolarity, and fluid balance were carried out for 4 hours. urine output was replaced volume for volume with 5% dextrose in 0.45% nacl solution. we tested the hypothesis that patients with high (greater than or eq ... | 2010 | 3116451 |
| captopril in a hyponatraemic hypertensive: need for caution in initiating therapy. | | 1999 | 85145 |
| resection of a massive arteriovenous malformation of the head and neck. | we report a patient with a massive arteriovenous malformation of the head and neck treated by surgical extirpation of the lesion. arteriography, hypotensive hypothermic anesthesia, and the intraoperative use of the doppler flowmeter were most helpful in this case. | 2003 | 154679 |
| bcr-abl oncogene renders myeloid cell line factor independent: potential autocrine mechanism in chronic myeloid leukemia. | in chronic myeloid leukemia (cml), a chromosome translocation has fused the bcr gene to the c-abl oncogene, such that a chimeric bcr-abl polypeptide can be made. to explore the biological properties of bcr-abl and compare them with those of the abelson virus (amulv) transforming gene (gag-v-abl), we have used either a synthetic bcr-v-abl gene that mimics the translocation product or, in some experiments, a bcr-c-abl cdna. a new retroviral vector was used to introduce the genes into the factor-de ... | 2011 | 3147434 |
| the liver and metabolic bone disease. | | 2013 | 3837818 |
| degradation products and the role of coagulation in "persistent" glomerulonephritis. | | 2016 | 4931741 |
| [effect of anaprilin on the clinical course of stenocardia and the carbohydrate metabolic indices of ischemic heart disease patients in relation to the nature of their glucose tolerance]. | fourteen-day anaprilin treatment of coronary patients with varying glucose tolerance has demonstrated that the drug's therapeutic efficiency was greater in patients with normal glucose tolerance. anaprilin caused a moderate drop in baseline glucose level and considerably limited the degree of hyperglycemia in response to the glucose tolerance test in coronary patients with abnormally low glucose tolerance. insulin content was virtually unaffected by the drug, irrespective of the type of glucose ... | 1991 | 3327995 |
| cleavage specificity of the serine protease of aeromonas sobria, a member of the kexin family of subtilases. | subtilisin-like proteases have been grouped into six families based on a sequence of the catalytic domain. one of the six is the kexin family, of which furin is a representative protease. all members of the kexin family, except one, are from eukaryotes. the one prokaryotic protease is a serine protease of aeromonas sorbria (asp). here, we examined the substrate specificity of asp based on the cleavage of short peptides. the results showed that asp preferentially cleaves the peptide bond followin ... | 2006 | 16487335 |
| cystic neoplasms of the pancreas. | eight patients with cystic neoplasms of the pancreas were seen at four northern california hospitals between the years 1978 and 1986. three of the tumors were benign and five were malignant. three females, whose average age was 61 years, had cystadenomas. three females and two males, whose average age was 48 years, had mucinous cystadenocarcinomas. clinical presentations were similar among all patients. abdominal pain was a prominent feature. anorexia, weight loss, nausea and vomiting with a pal ... | 2008 | 2446398 |
| repeated hepatic ischemia as a treatment for carcinoid liver metastases. | hepatic ischemia has been used in the treatment of bilobar malignant carcinoid tumors in the liver. hepatic artery ligation, hepatic dearterialization, and embolization with nondegradable micromaterial have been followed by collateral formation and are associated with a high complication rate. to reduce this, an implantable vascular occluder permitting intermittent occlusion of the hepatic artery was used in 3 patients with bilateral malignant carcinoid in the liver, with high urinary excretion ... | 2009 | 2741468 |
| lead toxicity and iron deficiency in utah migrant children. | we determined the frequency of presumptive iron deficiency and lead toxicity in 198 utah migrant children, ages 9-72 months, during the summer of 1985. there were no confirmed cases of lead toxicity. thirteen per cent of those tested and 30 per cent of the children ages 9-23 months were iron deficient. hematocrit determinations accurately predicted iron deficiency in only 35 per cent of the children confirmed to have this disorder via erythrocyte protoporphyrin screening. | 2009 | 2650572 |
| [immunohistochemical study of the differentiation of the cephalic lobe of the adenohypophysis in chick embryos]. | it was shown by means of indirect immunofluorescence that acth appeared in the cephalic lobe of the chick embryo pituitary beginning from the 8th day of the development. a new tissue-specific antigen (a3) is revealed, which is localized in the cephalic lobe of adenohypophysis and becomes manifest at the 7th day of embryogenesis. quantitative analysis of acth and a3 localization in the cells of 11-day chick embryo adenohypophyses allows a conclusion that a3 is localized in corticotropic cells. | 2001 | 88969 |
| haemodilution and blood-flow. | | 1999 | 88643 |
| family life cycle resource center in the elementary school. | | 2001 | 98495 |
| mediator and cellular mechanisms in asthma. the philip ellman lecture 1990. | | 2007 | 2258848 |
| the politician-doctor nexus. | | 2013 | 3564142 |
| [indications and technic of proximal selective vagotomy of the gastric acid secretory zone]. | | 2014 | 4283143 |
| [electrophoretic study of cerebrospinal fluid proteins in gliomas of the cerebral hemispheres]. | | 2014 | 4299992 |
| resonance energy transfer in pepsin conjugates. | | 2016 | 4897805 |
| radiographic assessment of knee alignment after total knee arthroplasty. | standard anteroposterior standing radiographs (14 x 17-inch cassettes) and full-limb radiographs (51-inch) from a randomized group of 50 patients undergoing total knee arthroplasty between january 1985 and june 1986 were analyzed. the mean tibiofemoral angle on short films was 5.8 degrees valgus, compared with 7.2 degrees valgus on full-limb films. this 1.4 degrees discrepancy had a standard deviation of 2.2 degrees, emphasizing the measurement variability in any individual case. the distance fr ... | 2011 | 3361322 |
| prostacyclin overproduction in bartter's syndrome. | urinary excretion of 6-keto-prostaglandin f1alpha and thromboxane b2, the major metabolites of prostacyclin and of thromboxane a2, respectively, was measured by specific radioimmunoassays in five female patients with bartter's syndrome and in five normal female controls. the patients with bartter's syndrome excreted about four times as much 6-keto-pgf1alpha as the controls; their excretion of thromboxane b2 was no different from that of the controls. these data suggest that overproduction of pro ... | 2001 | 90861 |
| memory and anergy: challenges to traditional models of t lymphocyte differentiation. | traditional paradigms suggest that encounter with an antigen converts naive peripheral t cells into memory cells with less stringent requirements for activation and increased capacities for lymphokine production. recent evidence argues that this view may be over-simplified in two ways. first, an encounter with antigen in the absence of certain costimulatory factors can render a t cell anergic--that is, unable to respond to antigen under normal conditions. second, although cells of the memory t c ... | 2006 | 1563595 |
| a high containment polymodal pilot-plant fermenter--design concepts. | a 225 dm3 pilot-plant bioreactor system has been designed and constructed that is suitable for biohazardous fermentations. the design enables operation at containment levels above the requirements of good industrial large-scale practice (gilsp) without secondary containment of the whole plant. the main biosafety features of the systems include the use of steam barriers on o-ring seals, supply lines and stirrer seals, multiple o-ring seals, piping of condensate lines and pressure relief systems t ... | 2006 | 1367227 |
| post-translational processing of anglerfish islet somatostatin precursors. | two distinct somatostatin precursors are synthesized in anglerfish (af) islets. in addition to a precursor which has somatostatin 14 (ss-14) as a c-terminal cleavage product, a precursor which contains at its c-terminus [tyr7, gly10] ss-14 as a potential cleavage product is also synthesized. however, even though an arg-lys pair is located immediately n-terminal to ala1 of the c-terminal tetradecapeptide, [tyr7, gly10]ss-14 was not found in significant amounts in extracts of af islets. instead, a ... | 2010 | 2863927 |
| darkroom diseases and how to combat them. | | 2011 | 3112384 |
| a new species of the early tertiary rodent thisbemys. | | 2013 | 3716069 |
| [closed fracture of the hyoid bone body with the formation of the false joint]. | | 2016 | 4767991 |
| use of computerized data listings and activity profiles of genetic and related effects in the review of 195 compounds. | computer-generated listings of data from short-term tests for genetic and related effects (activity profile listings) were prepared for 195 compounds that included for each compound, the test system (identified by a three-letter code word), qualitative results and the lowest effective dose (led) or highest ineffective dose (hid) tested. a corresponding bar or line graph (activity profile) was also generated, in which test systems are displayed along the x-axis and the led or hid values along the ... | 2012 | 3367921 |
| mechanistic studies on the mononuclear znii-containing metallo-beta-lactamase imis from aeromonas sobria. | in an effort to understand the reaction mechanism of a b2 metallo-beta-lactamase, steady-state and pre-steady-state kinetic and rapid freeze quench electron paramagnetic resonance (epr) studies were conducted on imis and its reaction with imipenem and meropenem. ph dependence studies revealed no inflection points in the ph range of 5.0-8.5, while proton inventories demonstrated at least 1 rate-limiting proton transfer. site-directed mutagenesis studies revealed that lys224 plays a catalytic role ... | 2006 | 16939225 |
| [extracellular nucleases of phytopathogenic bacteria]. | | 2005 | 1214627 |
| very early presentation of pompe's disease and its cross-sectional echocardiographic features. | pompe's disease was diagnosed in a 23-day-old female infant with congestive cardiac failure and hypotonia. the cross-sectional echocardiographic features of this case are described. the possible implications of this extremely early presentation are discussed. | 2012 | 3308716 |
| [unusual fetomaternal blood group antagonism]. | | 1998 | 105299 |
| [general anesthesia and long term psychotropic treatments]. | anesthesists often ask for withdrawal of psychotropic treatment a few days before surgery. usually they do not differentiate among the various classes of psychotropic drugs. some drugs, including mao inhibitors and reserpine-like agents, can induce or precipitate accidents; however, this does not occur with other types of antidepressants, neuroleptics and minor tranquilizers. the authors review the psychiatric risks related to such withdrawals; these risks are to be considered. they report that ... | 1998 | 105865 |
| cerebrospinal fluid-, blood-, and ascitis-catecholamines in hepatic cirrhosis. | the consideration of the extensive innervation of liver parenchyma, together with data relating to the degradation of catecholamines in the liver and the importance of hepatic vascular process in hepatic cirrhosis, prompted us to investigate the behaviour of catecholamines in this condition. the following parameters were measured in cerebrospinal fluid (csf), blood and ascitis fluid: total catecholamines, adrenaline and noradrenaline. during hepatic cirrhosis, total catecholamines level in blood ... | 1998 | 106413 |
| [pancreatic carcinoma on endoscopic retrograde pancreatico-cholangiogram (author's transl)]. | the pancreaticographic appearances of carcinoma of the pancreas have been divided into two types: 1. canalicular carcinoma arising from the duct system. if arising from the main pancreatic duct, it occludes this, or causes displacement or deformity of its branches in the immediate neighbourhood. if arising from branches, it causes cystic ectasia of the minor ducts; these appear fragmented and deformed while there is stenosis and displacement of the main duct. simultaneous origin from the main an ... | 1998 | 124684 |
| [unit for bleaching acrylamide gels]. | | 1999 | 91719 |
| diminished cellular immunity due to impaired nutrition in oesophageal carcinoma. | the nutritional status of 15 negro patients suffering from unresectable carcinoma of the midthoracic oesophagus was evaluated before and after palliative pulsion intubation. all were shown to be in negative nitrogen balance and to have a compromised non-specific cellular immune response. correction of protein-calorie malnutrition and the achievement of positive nitrogen balance were associated with an increase in absolute lymphocyte and t lymphocyte numbers and a significant increase in lymphocy ... | 1999 | 96903 |
| increase in leg blood-flow by normovolaemic haemodilution in intermittent claudication. | normovolaemic haemodilution down to a packed-cell volume of 35% was done in 10 patients with stable intermittent claudication. for a mean reducation in the packed-cell volume of 21.5% there was a 170% increase in peak calf blood-flow and a 111% increase in haemoglobin delivery. 7 of the 10 patients reported an increased walking distance. normovolaemic haemodilution may be of use in the management of some patients with peripheral vascular disease. | 1999 | 89279 |
| thyrotoxicosis during pregnancy. | the diagnosis of thyrotoxicosis during pregnancy is difficult on clinical grounds only. the determination of free thyroid hormones or free thyroid hormone indices is important and is possibly supplemented by the trh stimulation test. thyrotoxicosis during pregnancy should always be treated actively. the authors recommend subtotal thyroidectomy if there are indications for surgical therapy (nodular goitre or large diffuse goitre). otherwise treatment with thyrostatic agents is used. after operati ... | 1999 | 84547 |
| two-week postnatal examination of infants. | | 2000 | 87641 |
| fetal antigens and prenatal diagnosis. | | 2000 | 89698 |
| [clinical and biological aspects of chronic brucellosis]. | the present study refers to 53 cases of chronic brucellosis admitted to the clinic or followed up in an out-patient unit for ten years (1962-1971). there was a total of 946 days in hospital and 1688 days of occupational disability, about 40% of the patients necessitating repeated hospitalization because of the relapsing course of the disease. this group of cases presented the classical dominant features of an occupational anthropozoonoses (90.5%). elements of visceral and tissular pathology, obv ... | 2002 | 128800 |
| [pneumatization of the paranasal sinuses. causes and symptoms of hypopneumatization]. | | 2002 | 127302 |
| [experience in combination of the educational and scientific work of students]. | | 2002 | 127158 |
| dl-2-keto-4-hydroxyglutarate-1. | | 2003 | 165381 |
| purification of cytochrome b from neurospora crassa and other sources. | | 2003 | 152379 |
| [ultrasonic localization for closed renal biopsy]. | | 2004 | 520913 |
| fred jenner hodges, ii, m.d. 1895--1977. | | 2004 | 375293 |
| geriatric patient care. opinions of a sample of nurses. | | 2005 | 1134987 |
| aeromonas rivuli sp. nov., isolated from the upstream region of a karst water rivulet. | two freshwater isolates (wb4.1-19(t) and wb4.4-101), sharing 99.9 % 16s rrna gene sequence similarity, were highly related to aeromonas sobria (99.7 % similarity; 6 bp differences). a phylogenetic tree derived from a multi-locus phylogenetic analysis (mlpa) of the concatenated sequences of five housekeeping genes (gyrb, rpod, reca, dnaj and gyra; 3684 bp) revealed that both strains clustered as an independent phylogenetic line next to members of aeromonas molluscorum and aeromonas bivalvium. the ... | 2011 | 20207806 |
| a simple centrifuge column for desalting protein solutions. | | 2005 | 543535 |
| health checks on patients 75 years and over in nottinghamshire after the new gp contract. | to investigate annual health checks for patients of 75 years and over required by the 1990 contract for general practitioners. | 2006 | 1393076 |
| a randomized trial of anticoagulation with warfarin and of alternating chemotherapy in extensive small-cell lung cancer by the cancer and leukemia group b. | the cancer and leukemia group b (calgb) conducted a prospective randomized trial to evaluate the role of warfarin and alternating chemotherapy in extensive small-cell lung cancer (sccl). after stratification for sex and performance status, patients were randomly assigned to receive chemotherapy with methotrexate, doxorubicin (adriamycin; adria laboratories, columbus, oh), cyclophosphamide, and lomustine (ccnu) (macc), or macc plus warfarin (macc + w), or mitomycin, etoposide, cisplatin, and hexa ... | 2008 | 2547030 |
| association between environmental microbiota and indigenous bacteria found in hemolymph, extrapallial fluid and mucus of anodonta cygnea (linnaeus, 1758). | bivalves filter and accumulate large numbers of microorganisms present in the harvesting water. a complete understanding of the balance between anodonta cygnea and the microbiota present in their surrounding environment remains incomplete. therefore, the aim of this study was to quantify and identify the indigenous bacteria in the biological fluids of a. cygnea collected from mira lagoon in northern portugal. the results showed vibrio metschnikovii and aeromonas sobria as the dominant groups. th ... | 2010 | 20349058 |
| salt in surroundings influences the production of serine protease into milieu by aeromonas sobria. | previously we have shown that the open reading frame 2 protein (orf2 protein), which is encoded at the 3 ' end of serine protease of aeromonas sobria (asp), functions as a chaperone protein in periplasm in the production of asp. both proteins, asp and orf2 protein, associate in periplasm and orf2 protein helps asp to take an active form. asp which is dissociated from orf2 protein emerges in milieu . in this study, we examined the effect of sodium chloride (nacl) in medium on asp production by a. ... | 2007 | 17951986 |
| activation of prothrombin by asp, a serine protease released from aeromonas sobria. | the effect of a serine protease (asp) secreted from aeromonas sobria on plasma coagulation was investigated. proteolytically active asp promoted human plasma coagulation in a dose-dependent manner. consistent with the preference for a factor xa-specific oligo-peptide substrate, asp produced enzymatic activity from human prothrombin but not from factors ix and x. asp cleaved prothrombin to produce enzymatically active 37 kda-fragment displaying the same molecular mass as alpha-thrombin. asp is th ... | 2007 | 18067862 |
| [new aspects of vitamin k prophylaxis in newborn infants and infants]. | discussion about vitamin k prophylaxis has again become a matter of major concern since cases of life threatening bleeding due to late onset vitamin k deficiency have been observed in germany. this review tries to summarize present knowledge about the clinical presentation, pathogenesis and the potential prevention of vitamin k deficiency caused bleeding in the neonatal period and infancy. | 2011 | 3785234 |
| bioaffinity sensors. | | 2011 | 3131631 |
| pattern-evoked cortical potentials and nuclear magnetic resonance imaging in total and partial agenesis of the corpus callosum. | we have examined two cases of agenesis of the corpus callosum without any associated abnormalities. they were accidentally detected in x-ray-computed tomography. total agenesis of the corpus callosum could be differentiated by nuclear magnetic resonance imaging from partial agenesis. they had moderately depressed stereopsis. visually evoked cortical potentials to pattern stimuli showed abnormal findings in binocular viewing, and vecp equi-potential maps were similar to those of normal controls. | 2011 | 4053962 |
| a word about words. | | 2012 | 3459834 |
| malignant hyperthermia in a renal transplant recipient. | | 2012 | 3318564 |
| [protein studies in cystic and peritoneal fluids of ovarian tumors with special reference to cea]. | the levels of total protein, ig, afp, beta-hcg, cea, sc, sp1 and alpha 2-pag were measured in cystic and peritoneal effusions obtained from 70 females with benign and malignant ovarian tumors. this study was carried out to test out parameters those are useful for tumor monitoring of ovarian cancer. our results indicate that determining cea in peritoneal effusions could be one of useful methods in tumor monitoring of mucinous cystadenocarcinomas in cases of known histology and praetherapeutic est ... | 2012 | 3376613 |
| wine, women, suspiciousness and advertising. | women college students (n = 66) viewed videotapes of a soap opera episode and a rock music program, ostensibly to evaluate the appeal of such material to college women. different versions of the videotape included zero, three or nine wine commercials. refreshments, including white wine, were available to the subjects. suspiciousness about the experiment was evaluated through an open-ended questionnaire, responses to which were independently content-analyzed by two scorers. major findings were as ... | 2012 | 3560952 |
| wine, women, suspiciousness and advertising. | women college students (n = 66) viewed videotapes of a soap opera episode and a rock music program, ostensibly to evaluate the appeal of such material to college women. different versions of the videotape included zero, three or nine wine commercials. refreshments, including white wine, were available to the subjects. suspiciousness about the experiment was evaluated through an open-ended questionnaire, responses to which were independently content-analyzed by two scorers. major findings were as ... | 2012 | 3560952 |
| [properties of lak cell activity and lak-generation in pbl isolated from patients with renal cell carcinoma]. | | 2012 | 3266646 |
| consumptive coagulopathy associated with aortic aneurysm. | | 2013 | 3605176 |
| [spontaneous hematomas of the rectus abdominis]. | | 2014 | 4264255 |
| propoxyphene. two fatalities due to overdose. | | 2014 | 4684062 |
| [status of motor neurons and the monosynaptic reflex arc before a simple voluntary movement]. | | 2014 | 4043622 |
| [colovesical fistulas]. | | 2014 | 3948747 |
| british medical association attacks cigarette smoking. | | 2014 | 3978493 |
| temporal and contextual cues as discriminative attributes in retardates' recognition memory. | | 2015 | 4704210 |
| [diagnosis of edema]. | | 2015 | 4488702 |
| aeromonas sobria corneal ulcer. | | 2003 | 12579184 |
| fluid secretion caused by aerolysin-like hemolysin of aeromonas sobria in the intestines is due to stimulation of production of prostaglandin e2 via cyclooxygenase 2 by intestinal cells. | to clarify the mechanisms of diarrheal disease induced by aeromonas sobria, we examined whether prostaglandin e2 (pge2) was involved in the intestinal secretory action of a. sobria hemolysin by use of a mouse intestinal loop model. the amount of pge2 in jejunal fluid and the fluid accumulation ratio were directly related to the dose of hemolysin. the increase over time in the level of pge2 was similar to that of the accumulated fluid. in addition, hemolysin-induced fluid secretion and pge2 synth ... | 2008 | 18086811 |
| efficacy of in-feed probiotics against aeromonas bestiarum and ichthyophthirius multifiliis skin infections in rainbow trout (oncorhynchus mykiss, walbaum). | the aim of this study was to assess the efficacy of in-feed probiotics as a preventive measure against skin infections caused by aeromonas bestiarum and ichthyophthirius multifiliis (ich) in rainbow trout. | 2008 | 18422955 |
| impaired plasma clottability induction through fibrinogen degradation by asp, a serine protease released from aeromonas sobria. | aeromonas sobria infection often advances to sepsis, in which interaction of bacterial components with plasma proteins possibly causes various disorders. this bacterium releases a serine protease (asp), a putative virulence factor, and binds to fibrinogen. to study the asp effect on fibrinogen, we incubated fibrinogen or plasma with asp and investigated their clotting elicited by thrombin, which converts fibrinogen to a fibrin clot. enzymatically active asp retarded plasma clotting in a dose-dep ... | 2008 | 18462393 |
| production of c5a by asp, a serine protease released from aeromonas sobria. | aeromonas sobria causes pus and edema at sites of infection. however, the mechanisms underlying these effects have not been elucidated. c5a, the amino-terminal fragment of the complement 5th component (c5), mimics these events. to investigate the involvement of c5a in the pathophysiology of a. sobria infection, we examined release of c5a from human c5 by a serine protease (asp), a putative virulence factor secreted by this bacterium. c5 incubated with enzymatically active asp induced neutrophil ... | 2008 | 18714034 |
| case reports: fatal necrotizing fasciitis caused by aeromonas sobria in two diabetic patients. | we report two rare cases of aeromonas sobria necrotizing fasciitis with sepsis in patients with diabetes. in both cases, immediate fasciotomy was performed and appropriate empiric antimicrobial therapy and intensive care were administered. however, the two patients died on day 2 and day 11, respectively, after admission as a result of multiple organ failure. when patients present with a rapid onset of skin necrosis and progressive sepsis, an aeromonas sobria infection or vibrio infection should ... | 2009 | 18800212 |
| toxin production by aeromonas sobria in natural environments: river water vs. seawater. | aeromonas are water-borne pathogens. they are halotolerant, which means that they can survive in environments whose salt content corresponds to that of seawater (3.0% nacl). however, the presence of aeromonas in seawater is extremely rare compared with that in river water. in this study, we tested the ability of aeromonas sobria to produce toxins in river water and seawater. first, we cultured a. sobria on skim milk agar plates supplemented with either river water (sarw) or seawater (sasw). the ... | 2008 | 19122681 |
| aeromonas fluvialis sp. nov., isolated from a spanish river. | a gram-stain-negative, facultatively anaerobic bacterial strain, designated 717(t), was isolated from a water sample collected from the muga river, girona, north-east spain. preliminary analysis of the 16s rrna gene sequence showed that this strain belonged to the genus aeromonas, the nearest species being aeromonas veronii (99.5 % similarity, with seven different nucleotides). a polyphasic study based on a multilocus phylogenetic analysis of five housekeeping genes (gyrb, rpod, reca, dnaj and g ... | 2010 | 19648345 |
| structural basis for the kexin-like serine protease from aeromonas sobria as sepsis-causing factor. | the anaerobic bacterium aeromonas sobria is known to cause potentially lethal septic shock. we recently proposed that a. sobria serine protease (asp) is a sepsis-related factor that induces vascular leakage, reductions in blood pressure via kinin release, and clotting via activation of prothrombin. asp preferentially cleaves peptide bonds that follow dibasic amino acid residues, as do kex2 (saccharomyces cerevisiae serine protease) and furin, which are representative kexin family proteases. here ... | 2009 | 19654332 |
| a novel method for the diagnosis of drowning by detection of aeromonas sobria with pcr method. | the acid digestion method has been widely used for the diagnosis of death by drowning, but it is not always sensitive. however, there has been no definitive method to replace acid digestion until now. we speculate that bacteria are more useful markers than plankton for the diagnosis of death by drowning. in this study, from the preserved blood samples of 32 freshwater drowning cases, specific dna fragments of aeromonas sobria, one of the most common aquatic bacteria, were examined using pcr. the ... | 2009 | 19766051 |
| cellular components of probiotics control yersinia ruckeri infection in rainbow trout, oncorhynchus mykiss (walbaum). | subcellular components of the probiotics aeromonas sobria gc2 and bacillus subtilis jb-1, when administered to rainbow trout, oncorhynchus mykiss, conferred protection against a new biogroup of yersinia ruckeri. thus, intraperitoneal or intramuscular injection of rainbow trout with cell wall proteins (cwps), outer membrane proteins (omps), lipopolysaccharides (lps), whole cell proteins (wcps) and live cells followed by challenge on day 8 with y. ruckeri led to 80-100% survival compared with 10% ... | 2010 | 19912460 |
| the carboxy-terminal tail of aeromonas sobria serine protease is associated with the chaperone. | asp is the only bacterial protease in the kexin group of the subtilisin family. previous studies have revealed that the orf2 protein encoded at the 3' end of the asp operon is required for asp to change from a nascent form into an active form in the periplasm. however, the mechanism by which orf2 makes contact and interacts with asp in the maturation process remains unknown. the present study examined the effect of mutations in the carboxy-terminal region of asp on the asp maturation process. bo ... | 2009 | 19954452 |
| quorum sensing in aeromonas species isolated from patients in malaysia. | bacterial quorum sensing signal molecules called n-acylhomoserine lactone (ahl) controls the expression of virulence determinants in many gram-negative bacteria. we determined ahl production in 22 aeromonas strains isolated from various infected sites from patients (bile, blood, peritoneal fluid, pus, stool and urine). all isolates produced the two principal ahls, n-butanoylhomoserine lactone (c4-hsl) and n-hexanoyl homoserine lactone (c6-hsl). ten isolates also produced additional ahls. this re ... | 2011 | 20544198 |