Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| [a dynamic model of the interaction of cones with bright horizontal cells in the carp retina]. | the dynamic model showing interaction between cones and l-type horizontal cells in the carp retina is discussed. the model is based on the intracellular recording of spectral responses of horizontal cells. the model equations describe the contribution of ionic channels to responses of cones and horizontal cells. the model permits predicting responses of photopic l-cells as a function of time. | 2009 | 2812137 |
| [a dynamic model of the interaction of cones with bright horizontal cells in the carp retina]. | the dynamic model showing interaction between cones and l-type horizontal cells in the carp retina is discussed. the model is based on the intracellular recording of spectral responses of horizontal cells. the model equations describe the contribution of ionic channels to responses of cones and horizontal cells. the model permits predicting responses of photopic l-cells as a function of time. | 2009 | 2812137 |
| proton motive force involved in protein transport across the outer membrane of aeromonas salmonicida. | many gram-negative bacteria export proteins to the exterior. some of these proteins are first secreted into the periplasm and then cross the outer membrane in a separate step. the source of energy required for the translocation is unknown. export of the extracellular protein proaerolysin from the periplasm through the outer membrane of aeromonas salmonicida is inhibited by a proton ionophore and by low extracellular ph. one possible explanation of these results is that a proton gradient across t ... | 1989 | 2814486 |
| response properties of normal observers and patients during automated perimetry. | automated perimetry was performed on both eyes of 54 normal subjects, 36 patients with ocular hypertension and normal visual fields, and 20 patients with early glaucomatous visual field loss to evaluate false-positive errors, false-negative errors, fixation losses, consistency of double determinations, and testing time. for all subject groups and response measures, large interindividual variation was found. no meaningful age-related changes were obtained for false-negative errors, false-positive ... | 2009 | 2818281 |
| response properties of normal observers and patients during automated perimetry. | automated perimetry was performed on both eyes of 54 normal subjects, 36 patients with ocular hypertension and normal visual fields, and 20 patients with early glaucomatous visual field loss to evaluate false-positive errors, false-negative errors, fixation losses, consistency of double determinations, and testing time. for all subject groups and response measures, large interindividual variation was found. no meaningful age-related changes were obtained for false-negative errors, false-positive ... | 2009 | 2818281 |
| [visualization of forensically important foreign bodies by direct roentgen magnification]. | the detection of foreign bodies of microscopic dimensions with radiographic techniques is limited by the size and density of the particle and the radiographic resolution. these restrictions can be of decisive value in case work. the high grade direct radiographic magnification technique was successfully used in preceding experiments. due to its 1 mu focal spot, this tube allows direct magnifications up to 250 times. in present studies, the advantages as well as the limitations of this new techni ... | 1989 | 2818477 |
| [visualization of forensically important foreign bodies by direct roentgen magnification]. | the detection of foreign bodies of microscopic dimensions with radiographic techniques is limited by the size and density of the particle and the radiographic resolution. these restrictions can be of decisive value in case work. the high grade direct radiographic magnification technique was successfully used in preceding experiments. due to its 1 mu focal spot, this tube allows direct magnifications up to 250 times. in present studies, the advantages as well as the limitations of this new techni ... | 1989 | 2818477 |
| construction of an excretion vector and extracellular production of human growth hormone from escherichia coli. | a new excretion vector, peap8, was constructed to develop an excretion system for escherichia coli. this plasmid, derived from peap37, carried the weakly activated kil gene of plasmid pmb9 [kobayashi et al., j. bacteriol. 166 (1986) 728-732] and the penicillinase promoter and signal region of an alkalophilic bacillus sp. to excrete foreign gene products. a gene for human growth hormone (hgh) was joined to this signal sequence through the hindiii site. the recombinant plasmid p8hgh1 thus construc ... | 1987 | 2820841 |
| effects of polymyxin b nonapeptide on aeromonas salmonicida. | in contrast to polymyxin b-susceptible gram-negative bacteria of human origin, the fish pathogen aeromonas salmonicida was resistant to sensitization by polymyxin b nonapeptide (pmbn) to hydrophobic antibiotics. similarly, sensitization of a. salmonicida strains by pmbn to the bactericidal action of brook trout (salvelinus fontinalis) serum complement was less pronounced than the similar effect of pmbn against other gram-negative bacteria in certain mammalian sera. the surface array protein (a l ... | 1987 | 2823698 |
| individual responses to converting enzyme inhibitors and calcium antagonists. | this study was designed to assess whether the acute blood pressure response of an individual hypertensive patient to a calcium antagonist or an angiotensin converting enzyme (ace) inhibitor is a good predictor of the long-term efficacy of these drug classes in this particular patient. the concept that good responses to ace inhibitors and calcium antagonists may be mutually exclusive was also tested. sixteen patients were included in a randomized crossover trial of enalapril, 20 mg daily, and dil ... | 2010 | 2830189 |
| mechanism of the epsp synthase catalyzed reaction: evidence for the lack of a covalent carboxyvinyl intermediate in catalysis. | in order to detect covalent reaction intermediates in the 5-enolpyruvylshikimate-3-phosphate (epsp) synthase reaction, we have investigated the interaction of epsp synthase with the reaction product epsp. an exchange of epsp-methylene protons could be demonstrated by incubating epsps with epsp in d2o. since trace amounts of contaminating pi would lead to reversal of epsps reaction and hence methylene proton exchange, we added pyruvate kinase, adp, mg++ and k+. under these conditions, any contami ... | 1988 | 2838023 |
| first available results of long-term carcinogenicity bioassay on detergency zeolites (ms 4a and ms 5a). | long-term experimental carcinogenicity bioassay was carried out on ms 4a and ms 5a zeolites. the materials were tested on sprague-dawley rats by intraperitoneal, intrapleural, and subcutaneous injection of 25 mg in 1 ml of h2o. the results of this bioassay (the onset of one peritoneal mesothelioma in a male rat treated by intraperitoneal injection of zeolite ms 4a) calls for further and more sophisticated tests on zeolites used as detergents. | 1988 | 2839094 |
| drug-induced place preference in rats with 5,7-dihydroxytryptamine lesions of the nucleus accumbens. | the conditioned place preference (cpp) paradigm was used to determine a role for serotonin in the nucleus accumbens in the mediation of the rewarding properties of d-amphetamine morphine and diazepam. the effect of these drugs on cpp was examined in controls and in animals with 5,7-dihydroxytryptamine lesions of the nucleus accumbans. the results from control animals confirmed that d-amphetamine (1.5 mg/kg, i.p.), morphine (2.0 mg/kg, i.p.) and diazepam (1.0 mg/kg, i.p.) produced place preferenc ... | 1988 | 2840924 |
| a naturally immunogenic virion-associated protein specific for hiv-2 and siv. | the genomic organization of hiv-1 and the family of hiv-2 and siv viruses is similar. however, there is an open reading frame, orf-x, that is present in hiv-2 and siv, but not in hiv-1. the extent of protein sequence conservation in orf-x between hiv-2rod and sivmac suggests that this open reading frame encodes a gene that may be important for infectivity or replication. here, we show that the orf-x products of sivmac and hiv-2sbl-6669 are virion-associated and that the introduction of a prematu ... | 1988 | 2842694 |
| a naturally immunogenic virion-associated protein specific for hiv-2 and siv. | the genomic organization of hiv-1 and the family of hiv-2 and siv viruses is similar. however, there is an open reading frame, orf-x, that is present in hiv-2 and siv, but not in hiv-1. the extent of protein sequence conservation in orf-x between hiv-2rod and sivmac suggests that this open reading frame encodes a gene that may be important for infectivity or replication. here, we show that the orf-x products of sivmac and hiv-2sbl-6669 are virion-associated and that the introduction of a prematu ... | 1988 | 2842694 |
| influence of immunomodulatory agents on bovine humoral and cellular immune responses to parenteral inoculation with bovine rotavirus vaccines. | sodium diethyldithiocarbamate (dtc), mycobacterium cell wall extract (mcwe, regressin), killed corynebacterium parvum (c. parvum, immunoregulin) and muramyldipeptide (mdp) were each combined with purified, live bovine rotavirus and inoculated into 3 month-old holstein-friesian calves in order to examine their ability to potentiate specific humoral and cellular immune responses. the vaccinated calves were boosted twice at 3 and 6 weeks after initial vaccine inoculation. the rotavirus was administ ... | 1988 | 2847397 |
| analysis of a large cluster of nonessential genes deleted from a vaccinia virus terminal transposition mutant. | the principal objectives of this study were to analyze the structure and coding potential of a long segment of dna missing from a previously isolated (b. moss, e. winters, and j. a. cooper (1981) j. virol. 40, 387-395) attenuated variant of vaccinia virus strain wr and to examine the precise changes in the genome accompanying the deletion. the sequences of a 14.5-kbp region located at the left end of the standard vaccinia virus genome, extending from within the inverted terminal repetition (itr) ... | 1988 | 2849238 |
| [the entero-insular axis: the new incretin candidate glucagon-like peptide-1(7-36)amide (glp-1(7-36))amide]. | the functional connection between the gut and pancreatic islets is described by the term "enteroinsular axis". a humoral factor of the gut that might enhance the glucose-induced secretion of insulin is named "incretin". for many years glucose-dependent insulin-releasing polypeptide (gip) was the strongest incretin candidate. however, recent evidence suggests that glucagon-like peptide-1(7-36)amide represents a more potent physiological incretin. the sequence of glp-1 is identical in various mamm ... | 1988 | 2849249 |
| [chorioadenoma destruens. presentation of a case and review of the literature]. | 2009 | 2856452 | |
| preparation of low-density "endosome" and "endosome"-depleted golgi fractions from rat liver. | 1985 | 2859513 | |
| neural and pavlovian influences on immunity. | the traditional view that the nervous and immune systems are functionally independent (aside from general stress effects and autoimmune disorders of the nervous system) is being challenged by a new view that the nervous system regulates the activity of the immune system. if this is true, it should be possible to change the activity of the immune system by means of pavlovian conditioning, just as it is possible to condition other physiological events influenced by the autonomic nervous system or ... | 1985 | 2866484 |
| is vasoactive intestinal polypeptide the principal transmitter involved in human penile erection? | previous work from this laboratory reported on the effects of several autacoids and other agents on strips of human corpus cavernosum (cc) muscle. these investigations indicated the presence in the cc muscle of a) atropine-sensitive cholinoceptors, b) alpha- and beta-adrenoceptors and c) a non-adrenergic non-cholinergic mechanism. several recent publications have presented evidence in support of the possibility that vasoactive intestinal polypeptide (vip) is an important, or the chief, transmitt ... | 1986 | 2868132 |
| preserved hearing following excision of acoustic tumours. | 2008 | 2885629 | |
| congenital adrenal hyperplasia. | 2010 | 2887945 | |
| mechanism of action of somatostatin in the hippocampal slice. | 1987 | 2888131 | |
| importance of pulmonary blood volume and aortic blood pressure in regulation of left ventricular function. | 1988 | 2900297 | |
| effect of oversulphated chondroitin and dermatan sulphate upon thrombin and factor xa inactivation by antithrombin iii or heparin cofactor ii. | the kinetics of inhibition of human thrombin and factor xa by antithrombin iii or heparin cofactor ii were examined under pseudo-first-order conditions as a function of the concentration of naturally occurring oversulphated chondroitin and dermatan sulphates. the sulphated glycosaminoglycans (gags) studied were chondroitin sulphate d (csd) (glca-2-so4-galnac-6-so4), chondroitin sulphate k (csk) (glca-3-so4-galnac-4-so4), chondroitin sulphate h (csh) (ida-galnac-4,6-diso4) and polysulphated derma ... | 1988 | 2902851 |
| the role of central- and peripheral-type benzodiazepine receptors in anxiolytic-agent augmentation of nacl solution intake: effects of clonazepam and ro 5-4864. | two 1,4 benzodiazepines bind preferentially to the central- and peripheral-type benzodiazepine receptor in the brain, clonazepam and ro 5-4864, respectively. they were administered to rats to determine if the relation between known anxiolytic action and efficacy in augmenting nacl solution ingestion in rehydrating rats would remain the case for these prototypic agents. clonazepam (0.062-32.0 mg/kg, po) was highly potent and efficacious and increased 1.5% nacl solution intake in a dose-related fa ... | 1988 | 2905471 |
| three-dimensional structure of an open form of the surface layer from the fish pathogen aeromonas salmonicida. | cell-free culture supernatants of a lipopolysaccharide (lps) o-polysaccharide-deficient, single-insertion transposon mutant of the tetragonal surface protein array (s layer)-containing fish pathogen aeromonas salmonicida were examined by electron microscopy. negative staining showed that the s layer was released as sheets of tetragonal material, indicating that although surface retention of assembled s layer requires the presence of wild-type lps oligosaccharides, initial assembly of s-layer sub ... | 1989 | 2914846 |
| synthesis of glycoconjugates derived from various lipopolysaccharides of the vibrionaceae family. | conjugation of simple ketoses (such as 3-deoxy-d-manno-2-octulosonic acid and n-acetylneuraminic acid) and of various o-specific polysaccharides (from aeromonas hydrophila and aeromonas salmonicida) to the bifunctional spacer 1,6-hexanediamine, was achieved by reductive amination. the saccharide--1-(6-amino)-hexane alkyamines obtained were converted into the corresponding isothiocyanate derivatives and coupled to the free epsilon-amino group of lysine residues of the protein carrier bovine serum ... | 1989 | 2920731 |
| rigid fixation and bone grafts in craniofacial surgery. | 2010 | 2924485 | |
| oesophageal motility and lower oesophageal sphincter competence in progressive systemic sclerosis and localized scleroderma. | oesophageal motility and lower oesophageal sphincter (los) competence were investigated in 13 patients with progressive systemic sclerosis (pss) and in 16 patients with localized scleroderma (ls) by means of oesophageal manometry and 24-h ph monitoring of the distal oesophagus. results were compared with those of a control group consisting of asymptomatic volunteers. marked abnormalities in oesophageal motility and in acid exposure in the distal oesophagus were observed in pss patients only. the ... | 2010 | 2928728 |
| coronary angioplasty in myocardial infarction. | 2009 | 2933946 | |
| [changes in several indices of the hemostatic system in patients with genital cancer during the postoperative period]. | 2010 | 2935038 | |
| catecholamine release and potentiation of thromboxane a2 production by nicotine in the greyhound. | thromboxane a2 was generated by infusing arachidonic acid (2.5 micrograms ml-1) into an extra-corporeal circuit of blood withdrawn from anaesthetized dogs, and assayed on a blood-bathed bioassay cascade of porcine and bovine coronary artery strips, chick rectum and rat stomach strip. all tissues except chick rectum were treated with phentolamine and propranolol to abolish direct effects of catecholamines. the arachidonate-induced contractions of artery strips were abolished by a thromboxane synt ... | 1986 | 2937502 |
| minimal incision techniques for digital deformities. | we have presented basic minimal incision approaches to the more common digital deformities. we feel that with proper evaluation of the deformity and the patient, minimal incision surgery techniques give excellent long-term results with several advantages. these advantages include: less discomfort due to less surgical dissection. less need for internal fixation by careful use of compression dressings in the immediate postoperative period along with early ambulation. less disability. compression d ... | 2010 | 2937517 |
| electrostatic mechanism of survival of virulent aeromonas salmonicida strains in river water. | the ecological mechanism of survival of aeromonas salmonicida, the bacterial pathogen of fish furunculosis, in river water was investigated by laboratory-based experiments with two virulent strains (which were autoagglutinating) and two virulent strains (which were nonagglutinating). a difference in net electrical charge of a. salmonicida cells was detected by electrophoresis; cells of the virulent strains were negative, whereas cells of the avirulent strains were positive. despite the loss of v ... | 1986 | 2942106 |
| functional domains of the yeast regulatory protein gal4. | in the yeast saccharomyces cerevisiae regulation of the galactose/melibiose regulon rests on a dosage-dependent functional interplay between the positive regulator of transcription, the gal4 protein, and the negative regulator, gal80 protein. we have used this interplay to select in vitro generated fusions between the yeast adh1 promoter and gal4 coding sequence that overproduce gal4 protein, allowing the identification of gal4 protein in crude extracts from yeast. one type of these construction ... | 1986 | 2944111 |
| differential effects of serotonin (5-ht1a and 5-ht2) agonists and antagonists on renin and corticosterone secretion. | the present study was designed to investigate the effect of distinct serotonin (5-ht1a and 5-ht2) agonists and antagonists on renin and corticosterone secretion. low doses of the selective 5-ht1a agonists 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) (5.0-500.0 micrograms/kg, i.p.) and ipsapirone (tvx q 7821; 0.5-2.5 mg/kg, i.p.), and of the 5-hydroxytryptamine (5-ht) agonist mk-212 (2.0 mg/kg, i.p.), did not elevate plasma renin activity (pra) and concentration (prc) 30 min postinjection. ... | 1987 | 2952898 |
| differential effects of serotonin (5-ht1a and 5-ht2) agonists and antagonists on renin and corticosterone secretion. | the present study was designed to investigate the effect of distinct serotonin (5-ht1a and 5-ht2) agonists and antagonists on renin and corticosterone secretion. low doses of the selective 5-ht1a agonists 8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) (5.0-500.0 micrograms/kg, i.p.) and ipsapirone (tvx q 7821; 0.5-2.5 mg/kg, i.p.), and of the 5-hydroxytryptamine (5-ht) agonist mk-212 (2.0 mg/kg, i.p.), did not elevate plasma renin activity (pra) and concentration (prc) 30 min postinjection. ... | 1987 | 2952898 |
| applicability of coagglutination test for detecting aeromonas salmonicida antigens from extracts of bacterial cultures and experimentally infected tissues of the common carp (cyprinus carpio l.). | 1986 | 2953200 | |
| gender differences in variables associated with psychosocial adjustment to a burn injury. | the purpose of this study was to determine whether variables associated with psychosocial adjustment to a burn injury vary by gender. male and female burned subjects (n = 260) were compared on their functional disability, disfigurement, coping responses, social resources, and psychosocial adjustment to a burn injury. both men and women had adjusted psychosocially to their burn injury. less functional disability (r = .57, p less than .001) for men and greater problem-solving (r = .57, p less than ... | 2010 | 2964678 |
| immunoglobulin binding by the regular surface array of aeromonas salmonicida. | the cell surface of aeromonas salmonicida is covered by a regular surface array composed of a single species of protein, the a-protein (phipps, b. m., trust, t. j., ishiguro, e. e., and kay, w. w. (1983) biochemistry 22, 2934-2939). the array, known as the a-layer, is the key virulence factor for this organism. cells containing the a-layer specifically bound rabbit igg and human igm with high affinity (kd = 1.0 x 10(-6) m and 3.3 x 10(-6) m, respectively), but neither isogenic a-protein-deficien ... | 1988 | 2967820 |
| [current approaches to immunological diagnosis of autoimmune and immune complex diseases]. | 2010 | 2974642 | |
| [how can bivalves continue to close the shells?--regulation and a molecular mechanism on the economical catch contraction]. | 2010 | 2976172 | |
| technique for measurement of one-dimensional instantaneous ablation velocity. | an oscillating mirror scanned a he-ne laser beam along the length of a thin rod while the rod was ablated by an argon laser beam. the shadow of the scanning beam on an image plane provides a picture of the instantaneous ablation velocity of the rod. this configuration provides a unique method for investigating one-dimensional ablation. | 2010 | 2976448 |
| properties of an interphotoreceptor retinoid-binding protein from bovine retina. | washes and extracts of frozen and fresh cattle retina contain a water-soluble high-molecular-weight, retinoid-binding protein that is distinct from three other retinoid-binding proteins previously isolated from this tissue. the protein can be purified to apparent homogeneity from retinal homogenates by a combination of gel filtration, lectin, and ion-exchange chromatography. overestimation of the protein molecular weight was observed in several systems involving migration of the protein through ... | 1985 | 2981203 |
| middle tumor antigen of polyomavirus transformation-defective mutant ng59 is associated with pp60c-src. | we have found that lysis of mouse embryo cells infected with the polyomavirus host range transformation-defective (hr-t) mutant ng59 under gentle conditions that avoid ionic detergents results in detectable ng59-encoded middle tumor antigen (mtag) associated with pp60c-src. this mtag-pp60c-src complex could be immunoprecipitated from ng59-infected cell lysates by either sera from animals bearing polyomavirus-induced tumors or by monoclonal antibodies directed against mtag. immune complex kinase ... | 1985 | 2981329 |
| granular cell myoblastoma of the breast. | 2010 | 2991509 | |
| effect of epidermal growth factor on synthesis of prostaglandins and cyclic amp by embryonic palate mesenchymal cells. | the influence of epidermal growth factor (egf) on the ability of murine embryonic palate mesenchymal (mepm) cells to be stimulated to synthesize camp and prostaglandins was investigated. preincubation of mepm cells with egf enhanced, in a dose-dependent fashion, (1) the responsiveness of mepm cells to prostaglandin e1-induced elevation of intracellular levels of camp, and (2) the responsiveness of cells to calcium ionophore (a23187) and melittin-induced synthesis of prostaglandins e2 and f2 alph ... | 2010 | 2992494 |
| synthesis, export, and assembly of aeromonas salmonicida a-layer analyzed by transposon mutagenesis. | suicide plasmid pjb4ji, containing transposon tn5 and phage mu, was introduced into aeromonas salmonicida 449 which produces a surface protein array known as the a-layer. kanamycin-resistant exconjugants of 449 with altered ability to produce the a-layer were selected by virtue of their altered colonial morphology and color on medium containing the dye congo red. analysis of culture supernatants, periplasmic shock fluid, outer membranes, and whole-cell lysates by sodium dodecyl sulfate-polyacryl ... | 1985 | 2993248 |
| cyclophosphamide, doxorubicin and cisplatin chemotherapy for patients with locally advanced urothelial tumors with or without nodal metastases. | thirty-eight patients with primary urothelial tumors recurring in the pelvis or nodal presentation were treated with intravenous or intra-arterial cyclophosphamide, doxorubicin and cisplatin chemotherapy. the 38 patients were selected owing to unresectability by local criteria (12 patients) or by virtue of nodal metastases (26 patients). histologically, the patients either had pure transitional cell carcinoma (29), transformation to a histological subtype of transitional cell carcinoma (7) or pu ... | 2010 | 2993671 |
| demonstration of a stimulatory protein for virus-specified dna polymerase in phorbol ester-treated epstein-barr virus-carrying cells. | a heat-labile epstein-barr virus-specific dna polymerase stimulatory protein having a molecular mass of 45 kda was purified from phorbol 12-myristate 13-acetate-treated p3hr-1 cells by column chromatography. the virus dna polymerase stimulatory protein was precipitated by sera from patients with nasopharyngeal carcinoma but not by sera from healthy donors. the interaction of the stimulatory protein with dna polymerase was stoichiometric. furthermore, this protein stimulated epstein-barr virus dn ... | 1985 | 2994045 |
| macrophages as effector cells. introduction. | 2010 | 2996946 | |
| some pharmacological effects of tizanidine on smooth muscle organs and alpha 2-adrenoceptor. | microsomal and crude synaptosomal fractions were prepared from the longitudinal muscle of guinea-pig ileum. a specific binding of [3h]yohimbine (10 nm) to alpha 2-adrenoceptor in the crude synaptosomal fraction was inhibited by tizanidine and clonidine. tizanidine is about one-third as potent as clonidine. a specific binding of [3h]qnb (0.3 nm) to muscarine receptor in the microsomal fraction was inhibited by atropine (10(-8)-10(-7) m) but not by tizanidine (up to 10(-4) m). tizanidine inhibited ... | 1985 | 2996971 |
| [imaging of prostatic cancer by 1.5 tesla nuclear resonance tomography]. | twenty-two patients with histologically confirmed carcinomas of the prostate were examined by nuclear magnetic resonance, using a 1.5 tesla magnet (stage t1: one patient, t2: eight patients, t3: six patients, t4: seven patients). in 19 out of the 21 patients in stages t2 to t4, the tumour showed a specific signal intensity. in 12 cases, the tumour signal was more intense than from a normal prostate when using medium repetition and echo delay times; in 19 cases, multi-echo sequences with increasi ... | 1986 | 3008256 |
| complete dissociation between the activation of phosphoinositide turnover and of nadph oxidase by formyl-methionyl-leucyl-phenylalanine in human neutrophils depleted of ca2+ and primed by subthreshold doses of phorbol 12,myristate 13,acetate. | evidences have been provided by many laboratories that the activation of the nadph oxidase in neutrophils by formyl-methionyl-leucyl-phenylalanine (fmlp) is strictly linked to a transduction pathway that involves the stimulation, via gtp binding protein, of the phosphoinositide turnover and the increase in [ca2+]i. the results presented in this paper demonstrate that fmlp can activate the nadph oxidase by triggering a transduction pathway completely independent of phosphoinositide turnover and c ... | 1986 | 3008746 |
| [experimental nephritis induced by coxsackie b4 virus in mice--transient mesangial proliferation associated with acute viremia]. | 1986 | 3018334 | |
| benzodiazepine receptor binding is not altered in human epileptogenic cortical foci. | we measured benzodiazepine binding in cortical tissues from 13 patients with partial seizures. no differences in receptor density (bmax) or affinity (kd) were observed when epileptic foci were compared with nonspiking cortex. | 1986 | 3020475 |
| menadione (2-methyl-1,4-naphthoquinone)-induced ca2+ release from rat-liver mitochondria is caused by nad(p)h oxidation. | incubation of rat-liver mitochondria with menadione in the presence of succinate and rotenone resulted in rapid glutathione and nad(p)h oxidation followed by ca2+ release and mitochondrial swelling. ca2+ release, nad(p)h oxidation and mitochondrial swelling, were also observed in mitochondria from selenium-deficient rats. glutathione was only slowly oxidized, suggesting that glutathione oxidation, and subsequent nad(p)h oxidation via the glutathione peroxidase-glutathione reductase system were n ... | 1986 | 3020812 |
| pain, increasing girth in healthy japanese man. | 1986 | 3021791 | |
| pain, increasing girth in healthy japanese man. | 1986 | 3021791 | |
| identification of a conserved domain among cyclic nucleotide phosphodiesterases from diverse species. | partial amino acid sequences have been determined for the ca2+/calmodulin-stimulated cyclic nucleotide phosphodiesterase from bovine brain and the cgmp-stimulated cyclic nucleotide phosphodiesterase from bovine heart. examination of these sequences for homologous segments and comparison with protein sequences derived from the nucleotide sequences of the yeast pde2 gene and the drosophila dunce+ gene [chen, c.-n., denome, s. & davis, r. l. (1986) proc. natl. acad. sci. usa 83, 9313-9317; sass, p. ... | 1986 | 3025833 |
| the characterization of a conjugative r-plasmid isolated from aeromonas salmonicida. | we have analyzed two related r-plasmids isolated from aeromonas salmonicida: par32 and pja8102-1, which encode resistance to chloramphenicol, streptomycin, and sulfonamides (su). the genetic map of pja8102-1 indicated that this plasmid consists of at least three functionally different regions. one is the region conferring ability to transfer (tra), one is the region coding for drug resistance genes (r-det), and one is the region encoding the replication functions (rep). both plasmids contain rep ... | 1986 | 3027727 |
| the antihypertensive effect of angiotensin-converting enzyme inhibition: a multifaceted mechanism of action. | 2010 | 3030977 | |
| role of postnatal gonadal function in the determination of thyrotropin (tsh) releasing hormone-induced tsh response in adult male and female rats. | permanent effects of postnatal gonadal function on the hypothalamo-pituitary-thyroid axis were examined in male and female rats of the wistar-imamichi strain. animals were used at the age of about 10 weeks. neonatally castrated (nc) males showed a significantly higher plasma tsh response to trh (10 micrograms/kg bw, ip) than males castrated at 1, 2, 3, 4, or 6 weeks of age. the tsh response in intact males was similar to that seen in nc males. neonatal androgenization of nc males with 100 microg ... | 1987 | 3032567 |
| peculiarities of the endocrine time structure in noninsulin-dependent adult-onset (type ii) diabetes mellitus. | twenty noninsulin-dependent elderly diabetic patients, ten of whom were treated by oral hypoglycemic agents and ten of whom were regulated by diet alone, and 20 clinically healthy subjects matched for age, sex, height, and weight were examined with six blood and six urine samples at 4-hr intervals over a 24-hr span. plasma acth, cortisol, aldosterone, and dehydroepiandrosterone-sulfate (dhea-s) were determined by radioimmunoassay (ria); epinephrine, norepinephrine, and dopamine in urine were det ... | 2010 | 3037559 |
| evidence for oh-/h+ permeation across the peritubular cell membrane of rat renal proximal tubule in hco3(-)-free solutions. | membrane potentials and intracellular ph were measured on rat renal proximal tubular cells in vivo to test whether sodium-bicarbonate cotransport across the peritubular cell membrane accepts oh- (or h+ in opposite direction) or whether it requires the co2, hco3-, co3= buffer to operate. it was found that step changes of peritubular ph in nominally hco3(-)-free and co2-free solutions produced qualitatively similar initial potential responses and cell ph responses as changes in peritubular hco3- c ... | 1987 | 3039449 |
| fulminant leukemic polyradiculoneuropathy in a case of b-cell prolymphocytic leukemia. a clinicopathologic report. | a 52 year old man with a 10-month history of b-cell prolymphocytic leukemia (pll) died of an apparent acute fulminant polyradiculoneuropathy, a condition generally attributed to paraneoplastic complication. the pathologic examination disclosed diffuse leukemic infiltrations of the peripheral nervous system. it is suggested that this particularly aggressive form of b-cell chronic prolymphocytic leukemia presented a constellation of features that promoted the invasion of the peripheral nervous sys ... | 1987 | 3040217 |
| cloning of the gene for the surface array protein of aeromonas salmonicida and evidence linking loss of expression with genetic deletion. | a gene bank of dna from the fish pathogenic bacterium aeromonas salmonicida was constructed in the bacteriophage lambda gt11. phage lambda gt11/10g, a recombinant carrying a 4.0-kilobase fragment of a. salmonicida dna, was found to express the surface array protein (a protein) in escherichia coli. sodium dodecyl sulfate-polyacrylamide gel electrophoresis showed that the protein expressed from the cloned gene had a subunit molecular weight of 49,000, which was identical to that of subunits in the ... | 1987 | 3040676 |
| [non-invasive diagnosis of pre- and postpartum urination disorders]. | postpartal disorders of urinary discharge due to birth trauma are frequently the cause of rising infections of the urinary tract during the puerperium. in diagnosis, noninvasive methods should be preferred. bladder-emptying function was checked by means of uroflowmetry and sonographic measurement of residual urine in 83 patients at the department of gynecology and obstetrics at the rwth, aachen, in the third trimester and post partum. a considerable restriction of urine flow was found both prepa ... | 2010 | 3041696 |
| [non-invasive diagnosis of pre- and postpartum urination disorders]. | postpartal disorders of urinary discharge due to birth trauma are frequently the cause of rising infections of the urinary tract during the puerperium. in diagnosis, noninvasive methods should be preferred. bladder-emptying function was checked by means of uroflowmetry and sonographic measurement of residual urine in 83 patients at the department of gynecology and obstetrics at the rwth, aachen, in the third trimester and post partum. a considerable restriction of urine flow was found both prepa ... | 2010 | 3041696 |
| ventricular arrhythmias in normal individuals and athletes. | 2011 | 3042408 | |
| biphasic radiation-sensitivity of the transplantation immunity for rejection of an allogeneic ascites tumor. | transplantation immunity for second-set rejection of an allogeneic ascites tumor was induced by sensitizing mice with h-2-identical allogeneic spleen cells, and radiation-sensitivity of this immunity was studied. the immunity was not severely affected by 400 rads whole-body x-ray irradiation given at one day before the initial antigenic stimulation. in contrast, it was totally inactivated by 300-400 rads irradiation that was given one day before tumor challenge. an adoptive cell transfer experim ... | 2011 | 3042613 |
| [x-ray computed tomography in venous pathology]. | after presenting the tomodensitometric semiology of venous thromboses in various territories, the authors define its indications. it is essentially in deep territories, head, chest and abdomen that the ct-scan is used to study and diagnose unrecognized thromboses as well as determine the venous repercussion of various neighboring ailments. the respective place of the ct-scan, ultrasonography and various phlebographies is analyzed. | 2011 | 3043474 |
| acute neurogenic pulmonary oedema following generalized tonic clonic seizure. a case report and a review of the literature. | a case of acute neurogenic pulmonary oedema following a generalized tonic clonic seizure is presented. the condition is rare and the exact pathophysiology is unknown. pulmonary oedema is a serious complication of epileptic seizures, however, and the importance of awareness of this condition and its treatment is emphasized by a high mortality rate in older epileptics and by the demonstration of pulmonary oedema in recent series of young epileptics who died suddenly. | 2011 | 3053177 |
| melanoma antigen expression and metastatic ability of mutant b16 melanoma clones. | the biological functions of murine melanoma-associated antigens recognized by monoclonal antibodies (mabs) (m562, m622 and m2590) were examined by using mutant clones which differed in their degree of expression of these antigens. four clones of high expressors of 3 types of antigen (mea group), 5 clones of low or non-expressors of m562- and m622-recognizing antigens (meb group) and 4 clones of non-expressor of gm3 recognized by m2590 (mec group) were used. attachment of these clones to componen ... | 2011 | 3053466 |
| differential susceptibility of salmonid fishes to furunculosis correlates with differential serum enhancement of aeromonas salmonicida extracellular protease activity. | rainbow trout, atlantic salmon and brown trout, respectively, exhibit an increasing order of susceptibility to furunculosis. we investigated if this may be due to a differential sensitivity to exotoxins or ability to inhibit the exoprotease which is required by the bacterium to digest protein for growth. differences were slight in susceptibility to exotoxins and serum inhibition of exoprotease at high exotoxin:serum ratios. however, at low ratios brown trout serum markedly enhanced protease acti ... | 1988 | 3059141 |
| modulation by cytosolic ph of calcium and rubidium fluxes in rat pancreatic islets. | cytosolic ph (phi) of pancreatic islet cells was assessed using the fluorescent dye 2'7'-biscarboxyethyl-5'(6')-carboxyfluorescein (bcecf). phi was rapidly lowered by addition of the sodium salt of a weak acid or by treatment with amiloride. in the latter case, no recovery of phi occurred. nh4cl produced a rise in phi. stimulation of islet cells with glyceraldehyde produced a sustained fall in phi, whereas glucose and alpha-ketoisocaproate caused a small, gradual rise in phi. intracellular acidi ... | 1988 | 3060124 |
| [being a fan of delegated matters (aleksandr vasil'evich borisovskiĭ)]. | 2011 | 3064403 | |
| emphasis on preventive perinatology: a suitable alternative for developing countries. | the potential efficacy of preventive interventions in latin america to reduce perinatal morbidity and mortality is reviewed. the most important perinatal risk factors associated with pregnancy and delivery are young age of the mother, low socioeconomic status, low education, malnutrition, lack of prenatal care, pregnancy-induced-hypertension, perinatal infections, alcohol, smoking, and iatrogenic causes. adequate data are lacking to determine the magnitude of these factors in latin america. iatr ... | 2011 | 3065947 |
| retroviral transfer of genes into canine hematopoietic progenitor cells. | amphotropic retroviral vectors containing either the bacterial neomycin phosphotransferase gene or a mutant dihydrofolate reductase gene (dhfr*) were used to infect canine hematopoietic progenitor cells. successful transfer and expression of both genes in canine hematopoietic progenitor cells has been achieved as measured by the ability of the viruses to confer resistance to either methotrexate (mtx) or the aminoglycoside g418, respectively. gene transfer was achieved using helper-free retrovira ... | 1988 | 3066170 |
| chicken gonadotropin-releasing hormone ii increases plasma catecholamines in the bullfrog. | the aim of the present experiments was to test the effects of two native neuropeptides, [his5,trp7,tyr8]gonadotropin-releasing hormone (chicken gnrh ii) and [trp7,leu8]gnrh (salmon gnrh), on the sympathoadrenal system of chronically cannulated, conscious bullfrogs (rana catesbeiana). we observed that i.v. injection of chicken gnrh ii or salmon gnrh increased plasma noradrenaline and adrenaline concentrations, at doses that did not significantly affect arterial blood pressure or heart rate. chick ... | 1988 | 3067127 |
| the knowledge of human nutrition and the peoples of the world. | 1988 | 3067450 | |
| effect of acute ethanol administration on human blood aldehyde dehydrogenase activity. | the aldehyde dehydrogenase (ec 1.2.1.3) activity in human blood was measured after acute oral administration of two different doses of ethanol to healthy subjects. no changes in aldehyde dehydrogenase activity were observed in either of the two dose groups, as compared to control subjects receiving no ethanol. likewise, incubation of human whole blood samples with 20 mm ethanol for 2 hr caused no change in aldehyde dehydrogenase activity. the results show that human blood aldehyde dehydrogenase ... | 1988 | 3067608 |
| effect of acute ethanol administration on human blood aldehyde dehydrogenase activity. | the aldehyde dehydrogenase (ec 1.2.1.3) activity in human blood was measured after acute oral administration of two different doses of ethanol to healthy subjects. no changes in aldehyde dehydrogenase activity were observed in either of the two dose groups, as compared to control subjects receiving no ethanol. likewise, incubation of human whole blood samples with 20 mm ethanol for 2 hr caused no change in aldehyde dehydrogenase activity. the results show that human blood aldehyde dehydrogenase ... | 1988 | 3067608 |
| the t cell system in rheumatoid arthritis: activated or defective? | rheumatoid arthritis (ra) is characterised by the presence of activated lymphocytes in the synovial compartment, which are classically considered to be of particular importance to the pathogenesis of the disease. we have shown that activated lymphocytes are also found in the rheumatoid lymph nodes and peripheral blood, and that their proportions are increased in early or active disease. double-labelling experiments showed that t cell subsets within the activated circulating lymphocytes resemble ... | 2010 | 3075073 |
| drug-resistant plasmids from fish pathogens. | the epidemiological surveillance of drug-resistant strains of the fish pathogenic bacteria vibrio anguillarum and pasteurella piscicida carrying transferable r plasmids in fish farms is described. the dna structure of r plasmids, and the drug-resistant determinants of r plasmids from the fish pathogens aeromonas hydrophila,aeromonas salmonicida, edwardsiella tarda, v. anguillarum, and p. piscicida are discussed. | 1988 | 3079184 |
| milk-feeding maintains the prochymosin production in cells of bovine abomasal mucosa. | the effect of milk-feeding on the development of prochymosin-producing cells in bovine abomasal mucosa was studied using immunochemical methods. as long as the calf was fed milk both mucous neck, and chief cells in the gastric glands, were immunoreactive for prochymosin, the precursor form of a specific milk-clotting enzyme. after weaning, the prochymosin immunoreactivity in chief cells in the lower base of the gastric gland declined and finally disappeared. mucous neck cells and chief cells in ... | 1986 | 3083651 |
| ammonia contamination in a milk processing plant--wisconsin. | 1986 | 3084937 | |
| ammonia contamination in a milk processing plant--wisconsin. | 1986 | 3084937 | |
| blood lead levels among office workers--new york city. | 2010 | 3084941 | |
| blood lead levels among office workers--new york city. | 2010 | 3084941 | |
| nutritional rehabilitation of malnourished patients with cystic fibrosis. | we examined the effect of nutritional rehabilitation in cystic fibrosis patients with severe disease. thirteen malnourished patients (seven males, six females, age 7-27 yr) were studied over 7-16 mo. oral supplementation was attempted initially in 12 patients (mean duration 6.7 mo); only 2 patients gained weight, 2 withdrew, and 1 died. the remaining 7 patients failed to achieve adequate weight gain and were commenced on nasogastric supplementation with a semisynthetic formula. an additional pat ... | 2011 | 3085467 |
| annual summary 1984. reported morbidity and mortality in the united states. | 2011 | 3092006 | |
| experimental models of type-i diabetes. | 1986 | 3110756 | |
| darkroom diseases and how to combat them. | 2011 | 3112384 | |
| reliability of road accident statistics. | 2011 | 3112385 | |
| neuroanatomy of memory and amnesia: a case for multiple memory systems. | several different dissociable memory systems are considered in terms of their known or putative sites of pathology. in man, short-term memory can be selectively impaired by left hemisphere lesions near the acoustic projection area. there may be other modality-specific deficits. long-term memory is considered in terms of a) knowledge systems, b) stable associative memory; c) priming, and d) event memory, with special reference to the amnesic syndrome. for each of these categories, clinical neurop ... | 1987 | 3114179 |
| topical mitomycin c therapy for carcinoma of the bladder. | we studied 19 consecutive patients with biopsy proved carcinoma in situ of the bladder who had received 8 weekly doses of 30 mg. intravesical mitomycin c. followup with cystoendoscopy, biopsy and cytology studies every 3 months ranged from 6 to 48 months, with an average of 21 months. a complete initial response was achieved in 15 patients, 11 of whom have remained free of tumor with no further therapy. the 4 patients who failed to respond to initial therapy subsequently were free of tumor after ... | 2011 | 3118056 |