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natural killer cells in viral arthritis.changes in natural killer (nk) cell activity were studied in patients with polyarthritis associated with rubella or ross river virus infections. in 30 of 32 ross river virus patients, peripheral nk cell activity was depressed at some stage of the disease but returned to normal levels as patients recovered from arthritic symptoms. similar changes did not occur in rubella patients and no difference was found between changes in peripheral nk activity and serum interferon (ifn) levels in rubella pat ...19872443284
experimental induction of atypical hyperplasia in rat ventral prostate. 19872443923
mechanical stimulation of dorsal root ganglia induces increased production of substance p: a mechanism for pain following nerve root compromise?the undecapeptide, substance p, is known to be synthesized in cell bodies of dorsal root ganglia. this neuropeptide is also known to modulate sensory, nociceptive transmission postsynaptically on dorsal horn interneurons. in the animal model used in the current study, experimental mechanical stimulation of dorsal root ganglia and nerve roots increased the amounts of substance p, as well as substance p immunoreactivity in cell bodies of the dorsal root ganglia and in the substantia gelatinosa of ...19872443985
house dust mite-induced histamine release from washed blood cells. evaluation of effect parameters.in a selected group of 60 house dust mite allergic asthmatics, the correlation between the bronchial sensitivity to house dust mite and effect parameters of mite-induced histamine release from washed blood cells was evaluated. using a sensitive glass microfibre-based method, a significant positive correlation (r = 0.60; p less than 0.001) was found between bronchial allergen sensitivity and basophil cell sensitivity expressed as the house dust mite concentration necessary to give half the maximu ...20082446521
inhibition of the aeromonas salmonicida extracellular protease by alpha 2-macroglobulin in the serum of rainbow trout.one of the major pathogenic factors of aeromonas salmonicida, the bacterium causing furunculosis in fish, is considered to be a protease secreted in the extracellular products. this protease can be inhibited by normal trout and rabbit serum but the factor responsible has not hitherto been identified. the present results demonstrate that the a. salmonicida protease is inhibited by the alpha 2-macroglobulin of rainbow trout serum. this inhibitor accounts for about 9% of the total trypsin inhibitin ...19872461505
[therapy monitoring of regional chemotherapy by magnetic resonance spectroscopy]. 20082474953
[whipple's disease]. 20082475663
[treatment of decubitus ulcer with crilanomer and dextranomer].in a clinical study on decubital ulcers, 95 patients in 10 hospitals were treated with dextranomer and crilanomer. the size of the ulcer surface and the physician's evaluation of the healing status at the end of treatment served as the most important criteria for our assessment of the curative effect. both preparations proved equivalent in the statistical test. crilanomer revealed slightly better results than dextranomer with regard to the physician's overall evaluation al well as odor, exudatio ...20082483786
lack of effect by prostaglandin f2 alpha and verapamil on calcium uptake by isolated corpora lutea from pseudopregnant rats. 19892492809
[soy lipoxygenase as the object for the primary testing of potential inhibitors of leukotriene biosynthesis].the comparative study of the ability of three compounds (indomethacin, agent bw 755 c and arachidonate hydroxamic acid) to inhibit the activity of preparations of soya bean lipoxygenase and to block leukotriene c4 biosynthesis in human leukocytes recorded by reversed phase liquid chromatography was performed. it was shown that irrespectively of purification degree soya bean lipoxygenase is a sufficiently adequate object for primary testing of inhibitors of biosynthesis of leukotrienes with the g ...19892501105
the estimation of dietary protein intake in chronic renal failure.forty-five adult clinic patients with chronic renal failure each supplied a 4-day weighed dietary record, a 24-h urine collection, and a nocturnal spot urine sample. total nitrogen (n) losses derived from the urines were corrected for proteinuria and non-urea nitrogen excretion. individual estimates of n intake were compared by correlation and assessing the level of agreement. daily urea n excretion derived from the spot sample correlated well with the 24-h collection p less than 0.001, but the ...19892515492
cellular immune responses to plasmodium falciparum antigens in children receiving long term anti-malarial chemoprophylaxis.fifty-two gambian children who had received fortnightly chemoprophylaxis with maloprim, (pyrimethamine and dapsone), and 45 receiving placebo, were studied. cellular immune responses to malaria antigens, measured by lymphoproliferative responses and interferon production, were higher in children who had received prophylaxis than in controls, although the anti-malarial antibody levels were lower. during a one-year period after termination of prophylaxis, there was no increase in the frequency of ...19892515634
[assessment of nutritional status in the elderly]. 20082519421
reduction of aryl-nitroso compounds by pyridine and flavin coenzymes.1. a systematic kinetic investigation of the reduction of aryl-nitroso compounds by pyridine and flavin coenzymes and their analogs, in enzymatic and nonenzymatic systems, has been reported. 2. two main groups of nitroso compounds have been investigated, representatives nitroso-benzene and 1-nitroso-2-naphthol; in all enzymatic and nonenzymatic systems, the former was always reduced to phenyl-hydroxyl-amine and the latter to 1-amino-2-naphthol. 3. pyridine compounds included nadh, apad-4h2 and d ...20082531098
bile acid profile in a dog with cholangiocarcinoma. 19892536512
[clinical and biological considerations on adenocystic carcinoma of the head].the purpose of the present work was to define some aspects (i.e. the influence of histological grading on prognosis and the possibility of an eventual hormone dependency) of adenoidocystic carcinoma, a highly controversial form of carcinoma still open to debate. a study is thus reported of 33 cases of adenoidocystic carcinoma of the head and neck seen from 1965-1985 at the e.n.t. clinic of ferrara. the individual histological samples were seen over a period of time by a single histopathologist w ...20082548367
protection of rainbow trout against vibriosis and furunculosis by the use of attenuated strains of vibrio anguillarum.the fish pathogen vibrio anguillarum causes a lethal infection in rainbow trout (salmo gairdneri). three different avirulent mutants, constructed by transposon insertion mutagenesis (van20 and van70) or as antibiotic-resistant mutants (van1000), were isolated by screening 200 individual isolated mutants for avirulence. when used as live vaccines, all three avirulent mutants were able to induce protective immunity against the homologous as well as a heterologous strain of v. anguillarum. when van ...19892548446
enzyme polymorphism and clinical variability of diseases: a study of diabetes mellitus.we investigated possible relations among four common neonatal manifestations of diabetic pregnancy (macrosomia, hypoglycemia, hypocalcemia, jaundice) and four enzyme polymorphisms (pgm1, ada, ak1, acp1 in a sample of infants born of diabetic mothers. the pattern of associations observed between the two sets of variables is consistent with known differences in enzymatic activity within phenotypes of each system, suggesting that low enzymatic activity may have unfavorable effects on fetal developm ...19892556341
effect of glucocorticoids and limiting nursing on the carbohydrate digestive capacity and growth rate of piglets.the influence of glucocorticoid administration and limited nursing on piglet carbohydrase enzyme development and subsequent growth was examined in three experiments using 371 piglets. treatments in the first two experiments were formed by the factorial arrangement of hydrocortisone (-hyd or +hyd) and limited nursing (-ln or +ln) imposed form d 14 to weaning (d 28). hydrocortisone was replaced by adrenocorticotropic hormone (acth) in the third experiment. growth rates were severely depressed by h ...19892556355
antidepressants given repeatedly increase the behavioural effect of dopamine d-2 agonist.the effects of single or repeated doses of antidepressant drugs (imipramine, amitriptyline, citalopram, mianserin) on rat locomotor hyperactivity induced by quinpirole, a dopamine d-2 receptor agonist, was investigated. single doses of antidepressants do not change the effect of quinpirole, but enhance it when they are administered repeatedly. this enhancement is inhibited by (+/-)-sulpiride, a dopamine d-2 receptor antagonist. the results obtained indicate that the enhancement of dopaminergical ...19892569028
priapism: current concepts.the treatment options for the management of the patient with priapism have changed markedly within the past several years. when possible, the underlying cause of the priapism should be identified. therapy should be guided by the results of aspiration of the blood-filled corpora cavernosa of the erect penis. early intervention through pharmacologic manipulation or surgical shunting should not be delayed while trying conservative measures.20012569852
priapism: current concepts.the treatment options for the management of the patient with priapism have changed markedly within the past several years. when possible, the underlying cause of the priapism should be identified. therapy should be guided by the results of aspiration of the blood-filled corpora cavernosa of the erect penis. early intervention through pharmacologic manipulation or surgical shunting should not be delayed while trying conservative measures.20012569852
effects of long-term antihypertensive treatment with tertatolol on diastolic function in hypertensive patients with and without left ventricular hypertrophy.we assessed the effects of long-term antihypertensive treatment with 5 mg tertatolol, a noncardioselective beta-blocker, on left ventricular hypertrophy (lvh) and diastolic function. fifteen hypertensive patients were selected as good responders to previous treatment with tertatolol (supine blood pressure less than 140/90 mm hg). they were divided into 2 groups: group 1 with lvh (n = 6) and group 2 without lvh (n = 9). after a one month wash-out period, all patients received 5 mg tertatolol once ...20082573376
slip of rabbit striated muscle in rigor or amppnp.single glycerol-extracted rabbit psoas muscle fibres have been slowly extended either in rigor or in the unhydrolysable atp analogue, amppnp, and their sarcomere length, sarcomere structure and tension measured. the length of regularly arrayed sarcomeres, measured by optical diffraction, increased continuously as the muscle was stretched; the maximum sarcomere extension seen was approximately 6%. in the electron microscope sarcomeres from extended muscle fixed in rigor or amppnp remained regular ...19892592554
slip of rabbit striated muscle in rigor or amppnp.single glycerol-extracted rabbit psoas muscle fibres have been slowly extended either in rigor or in the unhydrolysable atp analogue, amppnp, and their sarcomere length, sarcomere structure and tension measured. the length of regularly arrayed sarcomeres, measured by optical diffraction, increased continuously as the muscle was stretched; the maximum sarcomere extension seen was approximately 6%. in the electron microscope sarcomeres from extended muscle fixed in rigor or amppnp remained regular ...19892592554
blastocystosis in italy. 20072596809
blastocystosis in italy. 20072596809
calcaneal gait in spastic diplegia after heel cord lengthening: a study with gait analysis.calcaneal gait or deformity can be a significant complication after heel cord lengthening. after heel cord lengthening, 20 children with spastic diplegia were evaluated by gait analysis to define calcaneal gait objectively and describe associated morbidity. mean age was 5 years 2 months (range 2 years 7 months to 8 years 2 months), and mean length of follow-up was 5 years 8 months (range 1 years 1 month 11 year 3 months). calcaneal gait was defined as dorsiflexion 1 sd beyond the mean in the sag ...20082600179
[a dermaerosion case dealing with a leakage of a chemically irrigable solution (naoci solution)].this paper is a report regarding a dermaerosion case dealing with a leakage of a chemically irrigable solution in a 3 year old boy. we are continuing to observe the dermal changes during as he grows. also, we carried out a pathological experiment on a rabbit and a patch test of the derm of seven people. the following conclusions were obtained. 1. we observed the dermaerosion of an epithelium repair after a complete elapse of one year. the dermaerosion of the corium could not be repaired but chan ...19892602703
the anomalous origin of the circumflex artery (ramus circumflexus) in the right aortic sinus: a case study.the anomalous origin of the circumflex artery in the right aortic sinus was recognized in one out of 123 human hearts. its independent ostium, located below the valve 2.5 mm behind the ostium of the right coronary artery, and 3.0 mm in front of the dorsal attachment of the sigmoid valve. it follows a retro-aortic course and its terminal distribution is exiguous, compensated by a coronary pattern of right predominance. there are no associated cardiac anomalies. finally, this knowledge is shown to ...19892610384
[microtrauma and cartilage injury].in addition to macrotraumas resulting from single and heavy impact, recurrent microtraumas are probably frequently the cause of cartilage damage. the risk of a microtraumatic cartilage damage exists especially in activities involving a high load frequency. epidemiological studies and dynamometric measurements in race events support this assumption. based on experimental investigations it is shown how the different components of the articular system-cartilage, synovial membrane and subchondral bo ...20082610669
purification of igg from serum with caprylic acid and ammonium sulphate precipitation is not superior to ammonium sulphate precipitation alone.immunoglobulin g (igg) from bovine serum raised against aeromonas salmonicida was purified by ammonium sulphate precipitation (asp) or caprylic acid treatment followed by ammonium sulphate precipitation (caas). purity of igg samples prepared by both methods were examined by high performance gel permeation chromatography, electrophoresis and antibody activity assay. results suggest that igg prepared by asp is better than that obtained by caas method in terms of the yield of the igg monomers and t ...19892612135
autofluorescence in human alveolar macrophages from smokers: relation to cell surface markers and phagocytosis.flow cytometry was used to study the influence of smoking histories on autofluorescence, expression of surface markers, and phagocytic ability in alveolar macrophages (am) recruited by bronchoalveolar lavage (bal) from healthy smokers (n = 13) and nonsmokers (n = 13). alveolar macrophages have an autofluorescence that can be quenched by a recently developed technique. in the present study, this technique was used in combination with flow cytofluorometry. alveolar macrophages from smokers (mean 1 ...19892612443
autofluorescence in human alveolar macrophages from smokers: relation to cell surface markers and phagocytosis.flow cytometry was used to study the influence of smoking histories on autofluorescence, expression of surface markers, and phagocytic ability in alveolar macrophages (am) recruited by bronchoalveolar lavage (bal) from healthy smokers (n = 13) and nonsmokers (n = 13). alveolar macrophages have an autofluorescence that can be quenched by a recently developed technique. in the present study, this technique was used in combination with flow cytofluorometry. alveolar macrophages from smokers (mean 1 ...19892612443
prp (proline-rich protein) genes linked to markers es-12 (esterase-12), ea-10 (erythrocyte alloantigen), and loci on distal mouse chromosome 6.the closely linked proline-rich protein (prp) genes, coding for abundant salivary proteins, are located on distal mouse chromosome 6. they are part of a conserved linkage group that is represented on human chromosome 12p. two other markers, ea-10 and es-12, that were previously unassigned to a chromosome are closely linked to prp genes in the mouse.19892613230
a preliminary study of brain gliomas with h17e2 monoclonal antibody: immunoscintigraphy and pharmacokinetics.ten patients with relapsing high grade brain gliomas and one patient with low grade glioma were studied with a monoclonal antibody (h17e2) against placental alkaline phosphatase. in addition 2 patients with relapsing high grade glioma were studied with a non specific antibody (4d513/2118). 1 mci of iodine-131-labelled h17e2 was administered intracarotidly (i.c.) in two, and intravenously (i.v.) in 9 patients. immunoscintigrams were taken at 0, 2, 24, 48 and 72 hours. radioactivity was monitored ...20082614081
a preliminary study of brain gliomas with h17e2 monoclonal antibody: immunoscintigraphy and pharmacokinetics.ten patients with relapsing high grade brain gliomas and one patient with low grade glioma were studied with a monoclonal antibody (h17e2) against placental alkaline phosphatase. in addition 2 patients with relapsing high grade glioma were studied with a non specific antibody (4d513/2118). 1 mci of iodine-131-labelled h17e2 was administered intracarotidly (i.c.) in two, and intravenously (i.v.) in 9 patients. immunoscintigrams were taken at 0, 2, 24, 48 and 72 hours. radioactivity was monitored ...20082614081
sequential, free and y internal thoracic artery grafts.the internal thoracic artery (ita) has excellent durability and its ability to survive for 10 years or more far exceeds the saphenous vein graft (svg). in an attempt to improve long-term survival from coronary artery bypass grafting (cabg), three or more (up to six) ita coronary anastomoses have been placed in 718 patients since 1982. initial flow in the ita immediately after grafting is critical to the success of the operation. careful dissection and preparation of the ita pedicle to prevent in ...20002627967
[socioeconomic aspects of depression]. 20092629567
importance of peak enzyme level and reinfarction while attempting to intervene myocardial infarction process.isosorbide dinitrate (isdn) was tried in 27 patients, of which 4 patients with evidence of reinfarction were excluded in the course of the study, with acute myocardial infarction, with the aim of reduction of enzymatically estimated infarction size. the drug apparently seemed useless, when overall effects of the therapy was looked into. but in the group, where drug was administered before the occurrence of peak enzyme level (pel), isdn could reduce infarction size by 22.95% (p less than 0.01). s ...20082630597
importance of peak enzyme level and reinfarction while attempting to intervene myocardial infarction process.isosorbide dinitrate (isdn) was tried in 27 patients, of which 4 patients with evidence of reinfarction were excluded in the course of the study, with acute myocardial infarction, with the aim of reduction of enzymatically estimated infarction size. the drug apparently seemed useless, when overall effects of the therapy was looked into. but in the group, where drug was administered before the occurrence of peak enzyme level (pel), isdn could reduce infarction size by 22.95% (p less than 0.01). s ...20082630597
automated biochemical identification of bacterial fish pathogens using the abbott quantum ii.the quantum ii, originally designed by abbott diagnostics for automated rapid identification of members of enterobacteriaceae, was adapted for the identification of bacterial fish pathogens. the instrument operates as a spectrophotometer at a wavelength of 492.600 nm. a sample cartridge containing 20 inoculated biochemical chambers is inserted in the path of the analyzing beam. reactions are converted into a 7-digit octal biocode, relayed via a sensor to the memory module, and compared to biocod ...19892644450
the search for the causes of breast and colon cancer.epidemiological studies of breast and colon cancers implicate diet as a causative factor but the evidence is stronger for colon cancer, the occurrence of which may be reduced by diets with less animal fat and more fruit and vegetables.20092648156
preventing nervous system sports injuries.physical fitness and sports remain integral components of overall good health and a cornerstone of preventive medicine. when performed safely, under adequate supervision, and with appropriate protective gear, most of these activities are enjoyable, healthful and psychologically gratifying. when not performed safely by trained athletes, these same activities can be treacherous, injurious and permanently disabling. the goals of this article are to review and describe low-risk and high-risk sports ...20082648209
preventing nervous system sports injuries.physical fitness and sports remain integral components of overall good health and a cornerstone of preventive medicine. when performed safely, under adequate supervision, and with appropriate protective gear, most of these activities are enjoyable, healthful and psychologically gratifying. when not performed safely by trained athletes, these same activities can be treacherous, injurious and permanently disabling. the goals of this article are to review and describe low-risk and high-risk sports ...20082648209
delivered volume during high-frequency ventilation. 19892648741
characterization of aeromonas salmonicida mutants with low-level resistance to multiple antibiotics.aeromonas salmonicida mutants selected for low-level resistance to small-molecular-mass antibiotics occur at frequencies that suggest point mutations and exhibit pleiotropic effects such as a multiple low-level antibiotic resistance, changes in outer membrane protein profiles, and loss of major exoprotease activity. multiple low-level resistance appeared as the result of decreased outer membrane permeability associated with a change from a 38.5- to a 37-kilodalton (kda) outer membrane protein. t ...19892653212
malignant hyperpyrexia. 19892653537
simultaneous chemo-radiotherapy with 5-fu/folinic acid/cis-platinum and accelerated split-course radiation in advanced head and neck cancer.in a clinical phase-ii trial, 62 previously untreated patients suffering from unresectable stage iii (4 patients) and iv (56 patients) squamous cell carcinoma of the head and neck were treated with a simultaneous chemoradiotherapy consisting of a 5-fluorouracil/folinic acid/cis-platinum combination and of an accelerated split-course radiotherapy. as results, 3 patients died from tumor arrosion bleeding during the treatment. the median follow-up time of the surviving patients is 27+ months (range ...20082654789
informed consent: a review.of paramount importance is the respect for autonomy and right to self-determination inherent in an ethically sound decision-making process. the president's commission clearly summarized the prevailing view of informed consent when it stated: "ethically valid consent is a process of shared decision making based on mutual respect and participation, not a ritual to be equated with reciting the content of a form that details the risks of a particular treatment or intervention".20092655496
combined grafting of bone marrow and thymus, and sequential multiple thymus graftings in various strains of mice. the effect on immune functions and life span.the combined grafting of young bone marrow and newborn thymus performed in old mice was effective in restoring the impaired immune functions, but the same treatment performed in middle-aged adult mice had no effect on the life span of c3h/mtv female mice. sequential multiple newborn thymus graftings starting at young adult age were effective in enhancing immunological functions, delaying the onset of tumor and extending the survival rate to certain degree in the first half of the experimental co ...20082664370
combined grafting of bone marrow and thymus, and sequential multiple thymus graftings in various strains of mice. the effect on immune functions and life span.the combined grafting of young bone marrow and newborn thymus performed in old mice was effective in restoring the impaired immune functions, but the same treatment performed in middle-aged adult mice had no effect on the life span of c3h/mtv female mice. sequential multiple newborn thymus graftings starting at young adult age were effective in enhancing immunological functions, delaying the onset of tumor and extending the survival rate to certain degree in the first half of the experimental co ...20082664370
[progress in cancer chemotherapy]. 20082666699
[progress in cancer chemotherapy]. 20082666699
heterogeneity of responses to lh-releasing hormone and phorbol ester among rat gonadotrophs: a study using a reverse haemolytic plaque assay for lh.protein kinase c (pk-c) has been implicated in the action of lhrh because lhrh-induced release of lh is partially mimicked by phorbol esters which activate pk-c, and reduced in magnitude by inhibitors of pk-c. we have used a reverse haemolytic plaque assay for lh to visualize and compare the direct effects on individual rat gonadotrophs of (1) a 2-h exposure to a range of concentrations of lhrh and phorbol 12-myristate 13-acetate (pma) and (2) a single maximally stimulatory dose (10 nm) of lhrh ...19892669809
oviducal storage of spermatozoa in the turkey: its relevance to artificial insemination technology.1. this paper addresses questions concerning the role of oviducal sperm selection and storage in the relative inefficiency of turkey reproduction. 2. before the onset of egg production, the turkey has the biological potential to store spermatozoa in its oviduct for periods up to 5 weeks; after the onset of production fewer spermatozoa are retained by the oviduct. 3. a better understanding of the biological mechanisms which regulate sperm selection and storage in the turkey oviduct is necessary t ...19892670069
induction of partial synchronization of leukemia cells by continuous infusion of low-dose methotrexate followed by citrovorum factor. 20092674461
sodium-transport nadh-quinone reductase of a marine vibrio alginolyticus.the respiratory chain of a marine bacterium, vibrio alginolyticus, required na+ for maximum activity, and the site of na+ -dependent activation was localized on the nadh-quinone reductase segment. the na+ -dependent nadh-quinone reductase extruded na+ as a direct result of redox reaction. it was composed of three subunits, alpha, beta, and gamma, with apparent mr of 52, 46, and 32 kda, respectively. the reduction of ubiquinone-1 to ubiquinol proceeded via ubisemiquinone radicals. the former reac ...19892687259
the quantitative relationship of lethality between extracellular protease and extracellular haemolysin of aeromonas salmonicida in atlantic salmon (salmo salar l.).an additive relationship of lethality between purified protease and haemolysin of the extracellular products (ecp) of aeromonas salmonicida was demonstrated by i.p. injection in atlantic salmon (salmo salar l.). the lethal toxicity of the combinations of protease and haemolysin follow a linear regression line y = -54.54x + 2400. the ld50 of protease and haemolysin when injected separately was 2400 ng/g fish and 44 ng protein/g fish, respectively.19892689276
[frequent diagnostic errors in diseases with exanthema]. 20092690505
[the cold chain: its role and significance in fighting infections controllable by specific prophylactic agents]. 20092694697
smoking among medical students in hong kong.a survey was conducted among two classes of medical students (n = 293) at the university of hong kong to study their smoking habits and knowledge of and attitudes toward smoking. the response rate was 97.3%. there was only one daily smoker (0.4%) and 21 occasional smokers (7.4%). while the respondents regarded health and self-discipline as the main reasons for not smoking, the social taboo against smoking among young people might have also deterred this educated elite from smoking. many of them ...19892700658
mechanical, biochemical, and structural effects of vitamin d deficiency on the chick heart.the effects of vitamin d deprivation on the chick heart were investigated from three aspects: cardiac contractility (+/- dp/dt), intracellular high-energy phosphorus compounds, and structural differences. four-week-old vitamin d-deficient chicks were divided into four groups: group a served as the normal group and received subcutaneous injections of cholecalciferol; groups b and c were vitamin d-deficient hearts but perfused differently; group d received daily subcutaneous injections of 5 microg ...19892705637
extracellular secretion of cloned aerolysin and phospholipase by aeromonas salmonicida.the promoterless structural genes for aerolysin and the extracellular phospholipase of aeromonas hydrophila were inserted into a multi-host-range expression vector and transferred into aeromonas salmonicida and escherichia coli. in both species, gene expression was under the control of the inducible tac promoter of the vector. neither the phospholipase nor the aerolysin was released by intact e. coli. instead, both proteins accumulated in the periplasm, leading to reduced growth and eventual cel ...19892708312
evaluation of infant feeding in acute gastroenteritis.sixty-eight bottle-fed babies under 9 months of age with mild acute gastroenteritis were observed to evaluate current feeding regimens following acute gastroenteritis in infancy. all babies were fed for 24 h with a glucose-electrolyte mixture (gem) and then randomly assigned to either a gradual reintroduction to their normal milk, i.e., slow regrade; immediate return to full-strength formula; or a rapid regrade to a hypoallergenic whey hydrolysate formula. all groups were well matched for age, s ...20092709254
the influence of type of tube and experience of the operator on performance of small bowel enema.seventy patients underwent small bowel enema (sbe) to assess the influence of experience of the radiologist on the ease of jejunal intubation and the adequacy of sbe using two types of tubes. comparing intubation time, intubation screening time, total screening time and total room time, we conclude that jejunal intubation is achieved easily, in a reasonable time with both types of tube, by all grades of radiologist, although the experienced operator using the silk tube achieved intubation in a s ...20092713604
determination of stereo- and positional isomers of oxygenated triterpenoids by reversed phase high performance liquid chromatography.twenty four oxygenated triterpenoids, including eight pairs of stereoisomers and five pairs of positional isomers, could be separated by reversed phase hplc. the capacity factors obtained in methanol-water and acetonitrile-water solvent systems made it possible to correlate the molecular polarities due to the presence of multiple oxygenated functional groups in these compounds. it was found that the number and position of functional groups as well as the stereochemistry of these functional group ...20092715731
incidence and causes of sepsis in glucose-6-phosphate dehydrogenase-deficient newborn infants.to determine the susceptibility to sepsis in newborn infants deficient in glucose-6-phosphate dehydrogenase (g6pd), we screened 33,943 saudi arab infants. deficiency of g6pd was found in 18%. sepsis was determined by the presence of clinical signs of sepsis and confirmed by positive blood cultures. sepsis was documented in 75 infants (2.2/1000). the incidence of sepsis was significantly higher in 6138 g6pd-deficient infants (3.4/1000) than in the 27,805 with normal g6pd activity (1.9/1000; p les ...20092715888
uncertainty and visual strategies in table tennis.ball games are characterized by perceptual uncertainty and time-pressure. of interest is the visual-search pattern carried out when these characteristics change. this is the case in table-tennis situations when comparing a drill situation, when one kind of stroke is constantly repeated, and a match situation, when the stroke is more often unpredictable. we analysed, during play, the visual-search pattern of five expert table tennis players to examine the effect of uncertainty on visual behavior. ...20092717357
genetic and biochemical characterization of the thymidine kinase gene from herpesvirus of turkeys.the thymidine kinase gene encoded by herpesvirus of turkeys has been identified and characterized. a viral mutant (atr0) resistant to 1-beta-d-arabinofuranosylthymine was isolated. this mutant was also resistant to 1-(2-fluoro-2-deoxy-beta-d-arabinofuronosyl)-5-methyluracil and was unable to incorporate [125i]deoxycytidine into dna. the mutant phenotype was rescued by a cloned region of the turkey herpesvirus genome whose dna sequence was found to contain an open reading frame similar to that fo ...19892724415
[imbecility of moderate degree in schoolchildren].the data of an experimental psychological investigation and self-service skills acquisition are presented for children with slight imbecility in three age groups: junior, middle and senior school-age. the peculiarities of the course of mental functions are discussed and potential intellectual capacities assessed in terms of the social and labor rehabilitation.20092728743
biomechanical considerations on some postoperative problems of directly anchored total hip replacements.uncemented total hip replacements have resulted in a higher incidence of postoperative complaints than cemented ones. the theoretical explanation of these not well defined discomforts is based on the differences of the stress and strain fields around the distal portions of the femoral components. while the noncemented stems are press-fitted and most of them tapered distally, thus creating hoop stresses and strains in the surrounding cortical bone, the shrinkage of the cement prevents these mecha ...20092738082
human gastric lipase. the n-terminal tetrapeptide is essential for lipid binding and lipase activity.human gastric lipase subjected to limited tryptic proteolysis lost its ability to hydrolyze emulsified long-chain triacylglycerol. activity against a water-soluble substrate was however retained, indicating that proteolysis did not affect the active site. sequence analysis revealed that trypsin specifically cleaved the linkage between lysine-4 and leucine-5. this cleavage rendered the enzyme unable to bind to emulsified triacylglycerol particles, e.g. human milk fat globules. we suggest that the ...19892753032
effects of systemic morphine upon a delta- and c-fibre evoked activities of subnucleus reticularis dorsalis neurones in the rat medulla.the effects of intravenous administration of morphine were examined on a delta- and c-fibre evoked activities of subnucleus reticularis dorsalis (srd) neurones in the rat medulla. this region may have an important role in nociception since srd neurones exhibit whole body receptive fields from which they can be activated preferentially or exclusively by noxious stimulation. the present study demonstrates that morphine can depress the c-fibre evoked responses of srd neurones in a dose-related (3-1 ...19892753082
identification and characterization of an 8-kd peptide stimulating late erythropoiesis.chronic renal failure is often associated with severe anemia, subnormal levels of erythropoietin (epo), and the presence of erythropoietic inhibitors. we studied an anephric patient with polycystic kidney disease maintaining a hemoglobin level of 13-14 g. biochemical, endocrine, and hematological parameters were all within normal limits. epo levels examined on two occasions during the clinical investigation were found to be low to subnormal. plasma of this patient supported human bone marrow ery ...19892753086
the dispersion of echinococcus granulosus in the intestine of dogs.we studied the dispersion of adult echinococcus granulosus in the intestine of experimentally infected dogs at 2 scales of habitat use. on a coarse scale, worms were found most frequently in the anterior third of the small intestine. on a fine scale, clumps or aggregations, typically of 4-5 worms in an area of 12 mm2, occurred throughout the anterior two-thirds of the intestine. the most likely proximate cause of aggregative behavior is attraction between individual worms. there are at least 2 e ...19892760768
the dispersion of echinococcus granulosus in the intestine of dogs.we studied the dispersion of adult echinococcus granulosus in the intestine of experimentally infected dogs at 2 scales of habitat use. on a coarse scale, worms were found most frequently in the anterior third of the small intestine. on a fine scale, clumps or aggregations, typically of 4-5 worms in an area of 12 mm2, occurred throughout the anterior two-thirds of the intestine. the most likely proximate cause of aggregative behavior is attraction between individual worms. there are at least 2 e ...19892760768
relationship between concentration and anticonvulsant effect of phenytoin against electroshock-induced seizures in rats: comparison of sampling sites for concentration determinations.the purpose of this investigation was to determine the optimum sampling site for phenytoin concentration measurements in the context of pharmacodynamic studies of the anticonvulsant effect of phenytoin. determination of drug concentrations in the serum, serum water, brain, and cerebrospinal fluid (csf) of rats as a function of time after iv injection of a 6-mg/kg dose revealed a significant disequilibrium between brain and serum water for 15 min and between csf and serum water for 5 min after in ...19892760817
2-bromo- and 16-bromo-estrogens and related compounds: potential inhibitors for both estradiol 2- and 16 alpha-hydroxylases in rat liver microsomes.kinetic studies of inhibition of estradiol 2- and 16 alpha-hydroxylase activities in male rat liver microsomes with 2-bromoestrogens, 4-bromo-estrone (4-bre1), 16 alpha- and 16 beta-bromoestrones and 16 beta-acetylthioestrone (16-acse1) were carried out. 2-bromoestrogens and 4-bre1 nonspecifically blocked the two enzyme activities in a competitive manner, and 2-bromo-estradiol (2-bre2) was the most potent inhibitor for the two hydroxylases among the 2- and 4-bromo steroids. kinetic data, the app ...19892761259
[break with a good examination tradition]. 20092763101
thermodynamics of intersubunit interactions in cholera toxin upon binding to the oligosaccharide portion of its cell surface receptor, ganglioside gm1.the binding and the energetics of the interaction of cholera toxin with the oligosaccharide portion of ganglioside gm1 (oligo-gm1), the toxin cell surface receptor, have been studied by high-sensitivity isothermal titration calorimetry and differential scanning calorimetry. previously, we have shown that the association of cholera toxin to ganglioside gm1 enhances the cooperative interactions between subunits in the b-subunit pentamer [goins, b., & freire, e. (1988) biochemistry 27, 2046-2052]. ...20092765522
endothelium-dependent inhibition of ergonovine-induced contraction is impaired in porcine coronary arteries with regenerated endothelium.the inhibitory effects of the endothelium against ergonovine-induced contraction were examined in isolated porcine coronary arteries under normal conditions and after endothelial regeneration. endothelium-dependent responses were examined in vitro in normal yorkshire pigs (n = 16) and in pigs that had undergone balloon endothelium removal of the left anterior descending coronary artery (lad) 4 weeks before the study (n = 10). the presence of a complete endothelial lining was confirmed histologic ...19892766515
unexpected sex-ratios in families of language/learning-impaired children.there is a well-documented propensity of males affected with developmental language/learning impairment. results from this study demonstrate, unexpectedly, that this sex-ratio difference of males to females with developmental language/learning disorders was found to occur significantly only in families with a language/learning-impaired mother. in addition, a remarkably aberrant offspring sex-ratio was found in families of language/learning-impaired children who had an affected mother, but not fa ...20092771037
[epidemiology of brucellosis. retrospective study of 246 hospital cases].246 cases of brucellosis registered by the medicine preventive service of miguel servet hospital for the period 1981-87 are retrospectively studied. it emphasizes the consumption of non controlled dairy products as the most frequent (54.5%) risk factor. a greater prevalence of professional and contact with cattle risk factors are observed in the male patients coming from rural areas.19892772348
time-resolved fluorescence study of vu-9 calmodulin, an engineered calmodulin possessing a single tryptophan residue.an engineered calmodulin (vu-9 calmodulin), which possesses a single tryptophan residue at position 99 in calcium binding domain iii, was studied by time-resolved fluorescence. at least two exponential terms are needed to describe the tryptophan fluorescence decays, either in the presence or in the absence of calcium. the characteristics of the fluorescence decays are strongly dependent upon the number of calcium ions bound per molecule of vu-9 calmodulin until half of the calcium sites are occu ...20092775754
ultrastructural study of the response of eosinophil granule cells to aeromonas salmonicida extracellular products and histamine liberators in rainbow trout salmo gairdneri richardson.intraperitoneal injections of aeromonas salmonicida extracellular products (ecp), compound 48/80 and concanavalin a were found to degranulate the eosinophil granule cells (egc) in the lower intestine and rectum of the rainbow trout salmo gairdneri richardson. ultrastructurally, the egc response resembled the anaphylactic granule extrusion of mammalian mast cells. varying degrees of granule vacuolation and loss of electron density occurred. labyrinthine channels were observed at the peak of degra ...19892776934
opening remarks of president fernando e. agrait on the occasion of the 50th anniversary of the cayo santiago macaque colony. 19892780954
production of human cells expressing individual transferred hla-a,-b,-c genes using an hla-a,-b,-c null human cell line.we detail in this report the characterization of a human b-lymphoblastoid cell line, .221, that does not express endogenous hla-a, hla-b, or hla-c class i ag due to gamma-ray-induced mutations in the hla complex. mutant .221 is characterized by: 1) complete absence of hla-a,-b,-c mrna transcripts and alpha-chains, and 2) intracellular expression of two non-a,-b,-c class i alpha-chains with an abundance less than or equal to 1% of normal hla-a,-b,-c expression on similar cells. however, transferr ...19892785140
[single photon emission computed tomography by using n-isopropyl-p-[123i]-iodoamphetamine and 99mtc-hexamethyl propyleneamine oxime in a patient with herpes simplex encephalitis].single photon emission computed tomographies (spects) by using n-isopropyl-p-[123i-imp]-iodo-amphetamine (123i-imp) and 99mtc-hexamethyl propyleneamine oxime (99mtc-hm-pao) were serially performed in a 70 yrs. old male with herpes simplex encephalitis (hse), and the chronological changes of accumulations were studied. accumulations of both 123i-imp and 99mtc-hm-pao increased initially, and then decreased with the stage of hse being advanced. the sequential appearance of the lesion in hse with 12 ...20092786584
effect of recombinant human granulocyte colony-stimulating factor on pneumocystis carinii infection in nude mice.repeated subcutaneous (s.c.) injections of recombinant human granulocyte colony-stimulating factor (rhg-csf) to pneumocystis carinii (p. carinii)-infected balb/c nude (nu/nu) mice had no effects on the number of the p. carinii cysts in the lungs, despite neutrophilic infiltration in the tissues and a marked increase in blood neutrophil count. this finding indicates that neutrophils in the absence of t cells do not play an important role in the killing of p. carinii. however, survival periods of ...19892787431
greed in healthcare. 20092798274
greed in healthcare. 20092798274
the effect of an additional task on sensorimotor performance in schizophrenics and neurotics. 20092800955
dengue haemorrhagic fever/dengue shock syndrome: lessons from the cuban epidemic, 1981.dengue haemorrhagic fever/dengue shock syndrome (dhf/dss) is one of the principal causes of hospitalization and death among children in several south-east asian countries. also, in the region of the americas, there has been an increase in the frequency of dengue fever epidemics and in the number of cases of dhf/dss. in 1981 an epidemic of dengue haemorrhagic fever occurred in cuba and this suggests that there is a high risk that such epidemics could recur in the region. the article summarizes th ...20092805215
dengue haemorrhagic fever/dengue shock syndrome: lessons from the cuban epidemic, 1981.dengue haemorrhagic fever/dengue shock syndrome (dhf/dss) is one of the principal causes of hospitalization and death among children in several south-east asian countries. also, in the region of the americas, there has been an increase in the frequency of dengue fever epidemics and in the number of cases of dhf/dss. in 1981 an epidemic of dengue haemorrhagic fever occurred in cuba and this suggests that there is a high risk that such epidemics could recur in the region. the article summarizes th ...20092805215
more on index of refraction. 20092805311
more on index of refraction. 20092805311
clinical and histopathologic correlation in patients with dilated cardiomyopathy. value of force-velocity product.to evaluate the relation between cardiac function and myocardial damage in patients with dilated cardiomyopathy (dcm), we compared echocardiographic parameters and histopathologic findings of the biopsied myocardium in 50 cases with dcm. as wall motion is much influenced by the increased afterload in cases with large ventricles, we generated a new contractile parameter, force-velocity product (fvp). fvp was defined as the result obtained by multiplying mean circumferential fiber shortening veloc ...19992810763
"a few bad apples?". 20092812134
"a few bad apples?". 20092812134
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