Publications

[isolation of yersinia pseudotuberculosis and edwardsiella tarda from a dead monitor lizard (varanus niloticus)].		1977	406717
edwardsiella tarda associated with osteomyelitis.	a case of osteomyelitis associated with edwardsiella tarda is reported. specimens from a wound exudate of a 58-year-old female with osteomyelitis revealed on a direct gram-stained smear, pleomorphic, gram-negative rods. growth of the organism on differential media and analysis of its analytab (api)(*) patterns produced results consistent with e. tarda. the identification of the organism was confirmed by the center for disease control, atlanta. this represents the first reported case of a wound i ...	1977	753935
[microbiological pollution of the environment due to breeding. i. enterobacteriaceae due to cattle breeding].	enterobacteriaceae from faeces of cattle belonging to four cattle farms situated in the ferrara district were investigated. at the same time, investigation was made of effluent sewage and recipient wells (upstream and downstream). the cattle (of the italian frisona breed) resulted uncontaminated by salmonellae, but proved to be very susceptible to arizona, citrobacter, shigella and s. gallinarum-pullorum infections, coming from the environment. predominant species in faeces were as follows: prot ...	1977	911464
enterobacteria of emerging pathogenic significance from clinical cases in man and animals and detection of toads and wall lizards as their reservoirs.	a total of 416 samples comprising faecal samples from diarrhoeic cases of man, calves, sheep and goats, and urine samples from patients with urinary tract infections, were examined for the presence of enterobacteria of emerging pathogenic significance. citrobacter freundii from 20, c. intermedius biotype-a from four, serratia marcescens (serotype 05:h13, bactericin type 16) from one and erwinia herbicola from two human stool samples were isolated. only two urine samples yielded c. freundii. citr ...	1978	582096
some interesting isolates from a diagnostic laboratory.	citrobacter koseri, plesiomonas shigelloides, edwardsiella tarda, yersinia enterocolitica, alkalescens dispar, vibrio parahaemolyticus, and vibrio alginolyticus were seven interesting microorganisms isolated recently in our diagnostic laboratory.	1978	641196
intestinal bacterial flora of the household lizard, gecko gecko.	a total of 114 isolates was recovered from the intestines of 43 househould lizards, gecko gecko. among the important ones were staphylococcus aureus, salmonella typhimurium, pseudomonas aeruginosa, proteus mirabilis and edwardsiella tarda.	1978	653125
isolation of edwardsiella tarda from three oregon sea mammals.	edwardsiella tarda was isolated from the peritoneal exudate of a steller's sea lion (eumetopias jubata) with peritonitis resulting from a perforating colonic ulcer; from the liver of a harbor porpoise (phocena phocena) with metritis and peritonitis sequela to dystocia; and from the liver of a california sea lion (zalophus californianus) with peritonitis following fracture and necrosis of a lumbar vertebrae. these findings indicate e. tarda is a common opportunistic invader in sick or injured mar ...	1978	691128
[childhood gastroenteritis caused by edwardsiella tarda].		1978	741022
cerebral aterial spasm. i. adrenergic mechanism in experimental cerebral vasospasm.	this study demonstrates that an adrenergic mechanism plays an important role in producing the delayed cerebral vasospasm which follows subarachnoid hemorrhage. results were as follows: 1. experimental subarachnoid hemorrhage (sah) was produced by injection of fresh arterial blood into the cisterna magna in cats. the cerebral vasospasm was shown angiographically to be biphasic in nature: immediate constriction lasting 1 h and marked prolonged spasm occurring between the 3rd and 5th day after sah. ...	1978	148833
[immunoprofile of lmif in immunologic deficiency syndromes. ii. mediator production by isolated subpopulations of human lymphocytes].		1978	149303
regulation of the in vitro anamnestic antibody response by cyclic amp. ii. antigen-dependent enhancement by exogenous prostaglandins of the e series.		1978	212208
suppressive effects on simian virus 40-induced oncogenesis of several immunosuppressive agents and hormonal modifications applied during the latent period.	the long latent period required for tumor induction with simian virus 40 (sv40) in the subcutis of hamsters can be used to investigate whether host factor(s) participate in oncogenesis. several treatments were applied during this period, and the results were compared with those of the same treatment applied in another series of experiments, homologous sv40 tumor grafting in hamsters. the results obtained were as follows: (a) the latent period for sv40 tumor induction in the female was shorter th ...	1978	214231
identification and characterization of normal and malignant human blood leukocytes by surface glycoprotein patterns.	we have labeled surface glycoproteins of normal and malignant human blood leukocytes by the galactose oxidase-nab3h4 and periodate-nab3h4 labeling techniques. the labeled glycoproteins were separated by slab gel electrophoresis in the presence of sodium dodecyl sulfate and visualized by fluorography. the different types of normal blood cells could be distinguished by their surface glycoprotein patterns. the surface glycoproteins of cells from patients with acute lymphoblastic, myeloid, or monobl ...	1978	291363
development of visual acuity in infant monkeys (macaca nemestrina) during the early postnatal weeks.		1978	96592
clinical relevance of the liver-specific lipoprotein (lsp).		1978	96648
catecholamine-induced alterations in glucose homeostasis in baboons, dogs, rabbits, and rats: comparative effects of somatostatin.		1978	98685
changes in composition of tears of malnourished children.		1978	98738
[isolation of edwardsiella tarda from duodenal juice and feces of a patient with chronic cholangitis (author's transl)].		1978	101616
heterologous radioimmunoassay for rabbit prolactin.	a highly specific heterologous double-antibody ria has been developed to measure rabbit prl by using guinea pig antiserum to human prl and ovine [125 i]iodo-prl. rabbit pituitary prl and serum give parallel dose-response curves in the assay and no cross-reaction (less than 0.1%) occurs with gh, placental lactogens, lh, fsh, or tsh from several different species. the assay is suitable for the measurement of human, ovine, bovine, caprine, and canine prl in addition to rabbit prl, but shows no cros ...	1978	105878
the role of catecholamines in clinical medicine.	the sympathetic nervous system is of major importance for the regulation of several physiological functions. drugs which inhibit the actions of catecholamines and adrenergic drugs are used in the treatment of many clinical disorders. the potential role of catecholamines in a number of human diseases has, however, until recent years been studied to a limited extent only due to lack of methods for quantitation of sympathetic nervous activity. after the development of enzymatic isotope-derivative a ...	1979	106629
a new principle of injectable depot contraceptives. i drug selection and studies in monkeys.	the aim of the investigations was to develop a long-acting depot contraceptive on the basis of norethisterone or levonorgestrel. disappointing results with levonorgestrel nonanoate and levonorgestrel undecylate showed that elongation of the fatty acid, esterified with the steroid, decreased the bioavailability of the latter due to incomplete hydrolysis of the ester. therefore, several new compounds were synthesized which contained a bifunctional molecule between the steroid and the fatty acid. i ...	1979	110513
effect of neonatal hypothyroidism and delayed l-triiodothyronine treatment on behavioural activity and norepinephrine and dopamine biosynthetic systems in discrete regions of rat brain.		1979	111295
renal malakoplakia with renal vein thrombosis.		1979	116513
hemolysins of edwardsiella tarda.	isolates of edwardsiella tarda from four sources produced nonfilterable hemolsin in trypticase soy broth. the cell-associated hemolysin was partially heat labile, destroyed by formalin and sensitive to treatment with trypsin. these characteristics, and the observation that ca++ or mg++ ions enhanced activity, suggest that a proteinaceous, enzymic component may be responsible for the hemolytic activity.	1979	34473
demonstration of an alpha2-macroglobulin receptor in human fibroblasts, absent in tumor-derived cell lines.		1979	87392
the role of p23,30-bearing human macrophages in antigen-induced t lymphocyte responses.		1979	88270
passive transfer in diabetes mellitus.		1979	88629
cell differentiation in human gastric gland as revealed by nuclear binding of tritiated actinomycin.	the nuclear binding of h3 actinomycin, which is closely linked to the differentiation phenomenon, was studied in human normal gastric mucosa. actinomycin binding decreases in cells which differentiate and becomes very low in fully differentiated cells. in the gastric pits, there is a decreasing gradient of labelling from the deeper stem cells to the well-differentiated superficial cells. this indicates that migration and renewal of the surface epithelium occurs following a 'pipe-line' system. al ...	1979	90638
[ultrastructural cytochemistry of the mouse juxtaglomerular apparatus (author's transl)].	the ultrastructural cytochemistry of the mouse juxtaglomerular apparatus has been studied. the specific granules of the juxtaglomerular cells were found to be argentaphobic when ultrathin sections of araldite-embedded renal cortex were stained according to the periodic acid-thio-carbohydrazide-silver proteinate technique of thiery. this technique revealed an abundant glycogen of type beta in the specific granules and in the cytosol of these cells. the rim of specific granules was positive when u ...	1979	92002
relations between statistical properties of spontaneous activity of lateral geniculate neurons and their anatomo-physiological features [proceedings].		1979	92234
the fate of transplanted pancreatic islets in the rat.	syngeneic pancreatic islets transplanted into the liver or the spleen reverse streptozotocin-induced diabetes in the rat, but allogeneic islets function only briefly and are rejected. shortly after transplantation, thrombi often form around transplanted tissue, particularly around nonislet tissue that contaminates islet preparations. these thrombi are a source of transient liver injury in recipients of intrahepatic grafts. a few days after transplantation, syngeneic islets injected into the port ...	1979	104625
transcription and translation in a pleiotropic streptomycin-resistant mutant of escherichia coli.	the role of the ribosomal protein s12 (streptomycin protein) in ribosome function and in other metabolic processes in the cell has been investigated. a spontaneous streptomycin-resistant strain of escherichia coli (sm3) carrying a mutation in the rpsl gene is deficient in its ability to induce the synthesis of the enzyme bets-galactosidase. it was demonstrated that the reduced rate of enzyme synthesis results from deficiencies in both the transcription of the lactose operon and translation of th ...	1979	104958
homology of the gene coding for outer membrane lipoprotein within various gram-negative bacteria.	the mrna for a major outer membrane lipoprotein from escherichia coli was found to hybridize specifically with one of the ecori and one of the hindiii restriction endonuclease-generated fragments of total dna from nine bacteria in the family enterobacteriaceae: e. coli, shigella dysenteriae, salmonella typhimurium, citrobacter freundii, klebsiella aerogenes, enterobacter aerogenes, edwardsiella tarda, serratia marcescens, and erwinia amylovora. however, among the enterobacteriaceae, dna from two ...	1979	104972
pharmacological control of reproduction cycles.		1979	380121
edwardsiella tarda in freshwater catfish and their environment.	edwardsiella tarda was isolated from 47, 88, and 79% of skin, visceral, and dressed-fish samples, respectively. this species was also isolated from 30% of imported dressed fish, 75% of catfish pond water samples, 64% of catfish pond mud samples, and 100% of frogs, turtles, and crayfish from catfish ponds. the incidence of edwardsiella increased during the summer months, as water temperatures increased. of several isolation media evaluated, the most effective was selective enrichment in double-st ...	1979	539822
benign pleomorphic adenoma of the larynx. a case report.	minor salivary gland tumors of the larynx are relatively rare. morphologically the majority of them are adenoid cystic carcinomas and the overwhelming location is the subglottic larynx. benign pleomorphic adenomas are rare minor salivary gland tumors of the larynx which usually occur at the glottic and subglottic levels. we present only the sixth case of a supraglottic benign pleomorphic adenoma that we could find in the literature. a preoperative laryngogram localized the tumor to the supraglot ...	1979	218487
quality of care on a psychogeriatric nursing unit in finland: focus on interaction skills.		1979	1319942
frequent isolation of edwardsiella tarda and pleisiomonas shigelloides from healthy zairese freshwater fish: a possible source of sporadic diarrhea in the tropics.	the intestinal contents of 59 zairese freshwater fish were examined for the presence of potential human enteric pathogens. edwardsiella tarda and plesiomonas shigelloides were isolated from 57 and 59% of them, respectively. for both microorganisms there was a significant difference between the isolation rates from lake and river fish: whereas e. tarda was much more frequently isolated from lake fish than was p. shigelloides, the reverse was observed for river fish. the authors hypothesize that s ...	1980	7387150
[interest of gamma-glutamyltransferase in "enterobacteriaceae" (author's transl)].	gamma-glutamyltransferase (gammagt) could be detected in 86,6% of 3,027 strains of enterobacteriaceae, by the use of gamma-l-glutamin-p-nitranilide acid for substrate. the following species produced gamma gt: citrobacter freundii, levinea malonatica, l. amalonatica, klebsiella pneumoniae, k. oxytoca, k. ozaenae, enterobacter aerogenes, e. cloacae, e. agglomerans, e. gergoviae, k. ozaenae, enterobacter aerogenes, e. cloacae, e. agglomerans, e. gergoviae, hafnia alvei, erwinia carotovora, serratia ...	1980	6104464
[edwardsiella tarda].		1980	6998221
extraintestinal human infection caused by edwardsiella tarda.	edwardsiella tarda is an uncommon enteric bacterium which has been found generally in animal hosts and occasionally in human feces. three cases of extraintestinal infection caused by e. tarda which are described herein include a typhoid-like illness, peritonitis with sepsis, and cellulitis from a wound acquired while fishing. the microbiology of e. tarda and the previous reports of infection due to this organism are reviewed.	1980	7381019
[edwardsiella tarda and plesiomonas shigelloides. their role as diarrhea agents and their epidemiology].	during a bacteriological investigation of infectious diarrhoea among the population of mopti, a town situated on the river niger in mali, a high prevalence of edwardsiella tarda and plesiomonas shigelloides in diarrhoeic stools was demonstrated. suspecting that the human infection originated from river fish, the prevalence of both bacterial species was studied in zairese freshwater fish. e. tarda and p. shigelloides were isolated from nearly 60% of the examined fish. it is concluded that these o ...	1980	7460120
gram-negative, aerobic, enteric pathogens among intestinal microflora of wild turkey vultures (cathartes aura) in west central texas.	the prevalence of gram-negative bacterial species in the intestines of 20 apparently healthy turkey vultures (cathartes aura) was determined. edwardsiella tarda, plesiomonas shigelloides, salmonella, and arizona hinshawii (salmonella arizonae) were each recovered from 15% of these birds. turkey vultures may be important reservoirs of these bacterial pathogens.	1981	7032423
edwardsiella tarda osteomyelitis in a patient with sc hemoglobinopathy.	edwardsiella tarda is a recently identified gram-negative organism of the family enterobacteriaceae. reports of human infections with e tarda have been infrequent. we review 14 cases of systemic edwardsiellosis reported in the literature and report a case of e tarda osteomyelitis in a patient with sickle cell-hemoglobin c disease. in our case the remains of a snake may have been the source of the organism. systemic edwardsiellosis is rare, and it may present as meningitis, endocarditis, bacterem ...	1981	7221628
comparison of two methods for same-day identification of enterobacteriaceae.	two commercial methods, api 20e (as modified for same-day enterobacterial identification) and micro-id, were evaluated for ability to provide useful same-day information of 368 clinically isolated enterobacteriaceae. organisms included escherichia coli (54), shigella (7), edwardsiella tarda (1), salmonella enteritidis (10), citrobacter (30), klebsiella (55), enterobacter (68), hafnia alvei (2), serratia (33), proteus (64), morganella morganii (24), providencia (18), and yersinia enterocolitica ( ...	1982	7051807
invasive enterocolitis caused by edwardsiella tarda.		1982	7054033
isolation and characterization of edwardsiella tarda from fall chinook salmon (oncorhynchus tshawytscha).	a new bacterial pathogen of chinook salmon (oncorhynchus tshawytscha) was isolated from fish in oregon's rogue river. the bacteria are biochemically and serologically related to strains of edwardsiella tarda. initially isolated from chinook salmon, the bacteria were also pathogenic for steelhead and rainbow trout (salmo gairdneri), and channel catfish (ictalurus punctatus). the 50% lethal doses for chinook salmon, steelhead trout, and channel catfish injected intraperitoneally and maintained in ...	1982	7103490
edwardsiella tarda gastroenteritis associated with a pet turtle.		1982	7200044
[antibacterial activities of cefotiam against various pathogens isolated from clinical materials (author's transl)].	bacteriological evaluation was made on cefotiam (ctm), a new broad-spectrum cephalosporin antibiotic, and the following results wer obtained. 1) ctm has shown very potent antibacterial activities against staphylococcus aureus, escherichia coli, edwardsiella tarda, citrobacter intermedius, salmonella, klebsiella, proteus mirabilis, proteus rettgeri, proteus inconstans, yersinia enterocolitica, aeromonas hydrophila, plesiomonas shigelloides and pseudomonas putrefaciens. 2) streptococcus faecalis, ...	1982	6285018
comparison of three methods for identification of enterobacteriaceae.	this study compares the ability of three commercial overnight methods, api 20e, minitek and enteric-tek, to accurately and completely identify 368 clinically isolated enterobacteriaceae without supplemental tests. organisms included escherichia coli (54 strains), shigella spp. (7), edwardsiella tarda (1), salmonella enteritidis (10), citrobacter spp. (30), klebsiella spp. (55), enterobacter spp. (68), hafnia alvei (2), serratia spp. (33), proteus spp. (64), morganella morganii (24), providencia ...	1982	6756905
characterization of plasmids in bacterial fish pathogen.	plasmid profiles of representative fish pathogens, aeromonas salmonicida, aeromonas hydrophila, vibrio anguillarum, pasteurella piscicida, yersinia ruckeri, edwardsiella tarda, and renibacterium salmoninarum, were determined by agarose gel electrophoresis with four different plasmid detection methods. a combination of two methods was required to detect the plasmids present in these strains and to calculate precisely the molecular weights of the plasmids. of 38 strains, 28 harbored one or more pl ...	1983	6822413
human edwardsiellosis traced to ornamental fish.	protracted diarrhea in a 2-month-old belgian infant was associated with edwardsiella tarda as the only potential pathogen. the same organism was isolated from a tropical aquarium fish in the home of the patient. the enteropathogenic role of e. tarda and the role of fish as a reservoir of infection are reviewed. additional observations, volunteer studies, and careful prospective surveys in tropical countries will be needed to produce firm evidence of the enteropathogenic potential of e. tarda.	1983	6826702
edwardsiella tarda isolated in israel between 1961 and 1980.	edwardsiella tarda was isolated from patients, water tortoises (clemmys caspica), and samples of water from lake kinnereth, the river jordan, well water, and sewage water. of the 53 isolates, 35 belonged to completely identified serotypes, among them 7 new ones. fourteen cultures had o antigens, and one had an h antigen, different from those previously described. three serotypes isolated from patients were also found in other sources: water tortoises, lake water, or both.	1983	6853692
the natural history of salmonellae in mammals of the tropical kimberley region, western australia.	screening for salmonellae was conducted on five occasions within a year on mammals from many different habitats in the mitchell plateau area of the tropical kimberley division of western australia. some data were obtained from reptiles. forty-two salmonella serotypes, two edwardsiella and one arizona strain were isolated. marsupials harbour significantly more (1.6 times) salmonella serotypes than eutherians. eleven salmonella serotypes and one arizona strain were isolated from reptiles. all salm ...	1983	6332007
[finding of the bacterial species edwardsiella tarda in the aquarium fish betta splendens].	a case of the mass occurrence of a disease in the aquarium fish species betta splendens is described; morphologically the disease was characterized by the finding of large dermal changes located mainly in the dorsal part and by miliary granulomata in liver, spleen and kidneys. the granulomata consisted of epitheloid light cells with centrally located necrosis. gram-negative bacteria with morphological and biochemical characteristics corresponding to the bacterial species edwardsiella tarda were ...	1983	6407179
[a case of sepsis caused by edwardsiella tarda].		1983	6413606
pathogenicity tests with strains of edwardsiella tarda: detection of a heat-stable enterotoxin.	a total of 25 strains of edwardsiella tarda isolated from various sources in different parts of the world between 1968 and 1982 was subjected to enteropathogenicity tests. a heat-stable enterotoxin was detected in three strains (12%). whereas culture filtrates gave doubtful results, concentration of toxin by ultrafiltration led to net fluid accumulation in the suckling mouse test and the rabbit ligated ileal loop assay. the enterotoxin resisted heating to 60 degrees c (30 min) and 100 degrees c ...	1983	6686399
[orthodontic and surgical approach to mandibular prognathia. prevention of recurrences].	the authors emphasize the necessity for a combined orthodontic and surgical approach to the problems posed by the treatment of mandibular prognathia. they feel that the major source of recurrences is related to the alveolar changes which accompany the new basal maxillo-mandibular relationship and the resultant modifications in muscular equilibrium. the prevention of recurrences must therefore take into account the prediction of adaptive remodelling of the alveolar processes.	1983	272713
neonatal shock in the first postnatal day.	advances in neonatal medicine have markedly reduced mortality in preterm infants. current emphasis should be placed on early detection and treatment of neonatal hypotension and shock. ideal clinical management includes perinatal recognition of low birth weight infants at risk for hypotension. all critically ill preterm infants should be closely monitored for tachycardia, hypotension, and/or decreased urinary output. by use of noninvasive blood pressure screening techniques, hypotensive infants m ...	1983	347923
[recent research on amalgams].		1983	272596
isolation of edwardsiella tarda and plesiomonas shigelloides from mammals and birds in zaïre.		1984	6531491
emblica officinalis reduces serum, aortic and hepatic cholesterol in rabbits.	emblica officinalis reduced serum cholesterol (p less than 0.001), aortic cholesterol (p less than 0.001) and hepatic cholesterol (p less than 0.001) significantly in rabbits. emblica officinalis did not influence euglobulin clot lysis time, platelet adhesiveness or serum triglyceride levels.	1985	3972094
simultaneous screening for two different antibodies in elisa by combining two solid phases: microtiter plate and falcon assay screening test system lid.	an enzyme-linked immunosorbent assay (elisa) is described that used a combination of 2 solid phases: a microtiter plate covered with a falcon assay screening test (f.a.s.t.) system lid. by coating each solid phase with a different antigen, it was possible to simultaneously detect 2 different antibodies. the results of the combined test were compared and found similar to those obtained in separate assays on the same solid phases by the usual elisa method. further, the combined test was more econo ...	1985	3882840
intestinal vascular effects of inhaled and locally administered enflurane in the cat.	the effects of enflurane on intestinal vascular resistance and blood flow in the intestine were studied in cats during basal chloralose anaesthesia. a jejunal segment was prepared and perfused with blood from both femoral arteries, allowing control of intestinal inflow pressure. mesenteric venous blood flow was measured with an optical drop recorder. during constant intestinal arterial pressure (75 mmhg; 10 kpa), intestinal vascular resistance was calculated during enflurane inhalation at mac 0. ...	1985	3993317
comparative in vitro activities of selected antimicrobial agents against edwardsiella tarda.	mics of 14 antimicrobial agents for 29 strains of edwardsiella tarda were determined by an agar dilution method. of the agents tested, ciprofloxacin, enoxacin, and norfloxacin were the most active on a weight basis. all strains were also susceptible to clinically achievable concentrations of ampicillin, chloramphenicol, tetracycline, trimethoprim, sulfamethoxazole, trimethoprim plus sulfamethoxazole, cefotaxime, and gentamicin. ninety percent of the strains demonstrated high-level resistance to ...	1985	4026271
local cerebral glucose utilization in normal female rats: variations during the estrous cycle and comparison with males.	the quantitative 2-[14c]deoxyglucose autoradiographic method was used to study the fluctuations of energy metabolism in discrete brain regions of female rats during the estrous cycle. a consistent though statistically nonsignificant cyclic variation in average glucose utilization of the brain as a whole was observed. highest levels of glucose utilization occurred during proestrus and metestrus, whereas lower rates were found during estrus and diestrus. statistically significant fluctuations were ...	1985	4040921
chronic enteritis associated with edwardsiella tarda infection in rockhopper penguins.		1985	4077643
[effect of titanium phosphate, zirconium oxide and a mixture of ammonium phosphotungstenate with zirconium phosphate on the elimination of radioactive cesium from the bodies of rats].		1985	3835674
vasomotion and transvascular exchange of fluid and plasma proteins.	the effect of spontaneous arteriolar vasomotion on the transvascular exchange of fluid and plasma proteins has been studied theoretically. the model combines fluid dynamic principles with a phenomenological approach to transvascular exchange on the basis of irreversible thermodynamics. the analytical treatment of the intravascular flow together with consideration of local changes of the morphology and vascular membrane characteristics makes it possible to determine the spatial and temporal varia ...	1985	3837174
theoretical mechanisms for synthesis of carcinogen-induced embryonic proteins: xiv. mutational and non-mutational mechanisms as subsets of a more general mechanism. part c. a defined cancer mutation.	the results of applying a mechanism of ethionine-induced embryonic gene derepressions to explain similar features found in hereditary tyrosinemia have been extended to a well defined cancer mutation. in all three cases, the described mechanism is compatible with the explanation for the etiology of embryonic like phenotypic expressions in cells and potentially for the carcinogenic process. the essence of the formulated process for a human bladder carcinoma mutation in the ras gene for a protein p ...	1985	3853079
[minimally transformed 3t3 cell lines as an object for research on the mechanisms of proliferation].	the present review gives a detailed description of mouse cell lines 3t3 (swiss 3t3, balb/c 3t3, and nih 3t3) including their establishment, evolution, growth properties and formation of the specific monolayer with low saturation density. questionable views of the 3t3 cell origin are discussed. the main features of these continuous cell lines are shown, such as a high requirement for serum growth factors, substrate dependence, inhibition of cell division in dense monolayer and absence of oncogeni ...	1985	3885522
gram-negative bacillary infections. pathogenic and pathophysiologic correlates.	gram-negative bacillary infections continue to be extremely important. escherichia coli is the single most frequently encountered pathogen, followed by organisms belonging to the tribe klebsiella-enterobacter-serratia and proteus-providencia. pseudomonas aeruginosa, although it receives considerable (perhaps excessive) attention, is found relatively less frequently, occurring principally in the hospitalized patient who is immunocompromised. many factors, both host and microbial, are responsible ...	1985	3890536
technetium-99m dtpa renal flow studies in goldblatt hypertension.	computer-assisted dynamic renal studies were performed on a group of 14 mongrel dogs before and after the induction of unilateral renal artery stenosis. ninety-second technetium-99m diethylenetriaminepentaacetic acid ( [99mtc]dtpa), 15-min [99mtc]dtpa, and 30-min iodine-131 orthoiodohippurate ( [131i]hippuran) time-activity curves were analyzed and correlated with reduction of renal blood flow as measured by electromagnetic flow probe and pah clearance techniques. parameters of the 90-sec [99mtc ...	1985	3897482
comparison of the regulatory regions of ilvgeda operons from several enteric organisms.	the nucleotide sequence preceding the ilvgeda operon has been examined and compared in five enteric organisms. the sequence in escherichia coli b was identical to the earlier-described strain k-12 sequence. the sequences of salmonella typhimurium and klebsiella aerogenes were remarkably similar to that of e. coli and identical in that part of the leader region that specified the putative 32-amino-acid peptide. thus, identical secondary structures could be postulated for the leaders of all three ...	1985	3900037
autoscan-4 system for identification of gram-negative bacilli.	a production model of the autoscan-4 system (american microscan, inc., mahwah, n.j.) was tested with not more than 11 strains each of 73 groups or species of gram-negative bacilli from various centers for disease control culture collections. the strains included typical and atypical strains of enteric fermenters, nonenteric fermenters, and nonfermenters. the autoscan-4 system identified 95.3% of all 405 cultures accurately: 95.4% of 307 members of the family enterobacteriaceae, 96.6% of 29 nonen ...	1985	3905849
determination of nanogram quantities of vanadium in biological material by isotope dilution thermal ionization mass spectrometry with ion counting detection.		1985	3907412
the potential dependence of the intestinal na+-dependent sugar transporter.	the unidirectional influx of the lipophilic cation tetraphenylphosphonium (tpp+) into isolated intestinal epithelial cells exhibits a marked dependence on the membrane potential (delta psi) maintained by or experimentally imposed on these cells. by taking advantage of this fact, we have described a "crossover" procedure that allows the relative permeability of a cation and anion pair to be determined. measurements of such relative permeabilities permits diffusion potentials of defined magnitude ...	1985	3911844
liver abscess caused by edwardsiella tarda.	edwardsiella tarda, among other enterobacteriaceae, is a rare isolate from clinical specimens in man. a liver abscess caused by e. tarda was found in a middleaged woman without overt epidemiologic exposure to known reservoirs of this organism. while the most likely source of infection was the bowel, we failed to demonstrate a gut carriage of e. tarda or to show any local condition predisposing to the development of the liver lesion.	1985	3911993
lhrh-agonist treatment in clinical and experimental human breast cancer.	thirty-one premenopausal patients with metastatic breast cancer were treated for 3-33 months with the potent lhrh-agonist buserelin (hoe 766) as a first-line therapy. twelve women (group ia) were treated with a daily dose of 3 x 400 micrograms buserelin intranasally and 10 women (group ib) with a daily dose of 2 x 1 mg subcutaneously after parenteral treatment with 3 mg per day in the first week. nine patients (group ii) were treated chronically with 3 x 400 micrograms buserelin intranasally in ...	1985	3935869
[physiological and pharmacologic studies of the adrenal medulla by the measurement of plasma catecholamine levels].	the new techniques for the assay of the plasma catecholamines: noradrenaline, dopamine and, most importantly, adrenaline, because of their sensitivity and precision, have provided new information about the physiology and the pharmacology of the adrenal medulla in animals and in man. the most effective of these new techniques are the radioenzymatic techniques. the activation of the adrenal medulla in the dog or the rat appears to be frequency-dependent by maintaining a fixed concentration ratio i ...	1985	2863423
evaluation of the alpha-1 and alpha-2 adrenoceptor-mediated effects of a series of dimethoxy-substituted tolazoline derivatives in the cardiovascular system of the pithed rat.	the alpha-1 and alpha-2 adrenoceptor-mediated effects of a series of dimethoxy-substituted tolazoline derivatives were investigated in the cardiovascular system of the pithed rat. the 2,5- and 3,5-dimethoxy-substituted tolazoline derivatives produced vasopressor responses that were inhibited by the alpha-1 adrenoceptor antagonist, prazosin (0.1 mg/kg i.v.), and were not affected by the alpha-2 adrenoceptor antagonist, yohimbine (1 mg/kg i.v.), suggesting that these derivatives selectively activa ...	1985	2981322
differential stability of host mrnas in friend erythroleukemia cells infected with herpes simplex virus type 1.	the consequences of herpes simplex virus type 1 infection on cellular macromolecules were investigated in friend erythroleukemia cells. the patterns of protein synthesis, examined by polyacrylamide gel electrophoresis, demonstrated that by 4 h postinfection the synthesis of many host proteins, with the exception of histones, was inhibited. examination of the steady-state level of histone h3 mrna by molecular hybridization of total rna to a cloned mouse histone h3 complementary dna probe demonstr ...	1985	2981326
characterization of an rna polymerase activity from hela cell mitochondria, which initiates transcription at the heavy strand rrna promoter and the light strand promoter in human mitochondrial dna.	an rna polymerase activity capable of initiating transcription at both the heavy strand rrna promoter and the light strand promoter of human mitochondrial dna has been partially purified from hela cell mitochondria and characterized in its requirements and products. the ratio of the two transcription initiating activities varied considerably from preparation to preparation. the human mtrna polymerase partially purified by deae-cellulose and heparin-agarose chromatography exhibits a great sensiti ...	1985	2981880
[effect of tunicamycin on human cytomegalovirus replication].		1985	2998078
[effects of 5 derivatives of 3-azabicyclo [3,3,1]nonanes on isolated guinea pig ileum myenteric plexus-longitudinal muscle].		1985	3020868
transitional cell carcinoma of the urinary bladder in a beluga whale (delphinapterus leucas).	a transitional cell carcinoma of the urinary bladder was found in a beluga whale stranded in the st. lawrence middle estuary. various organs of this animal were submitted to high resolution gas chromatography coupled with mass spectrometry analysis. high frequency of urinary bladder cancer in the human population of the same area and the presence of carcinogenic compounds in the marine environment of this animal are discussed.concurrent isolation of edwardsiella tarda from various organs of this ...	1985	17422578
acalculous cholecystitis and cytomegalovirus infection in the acquired immunodeficiency syndrome.		1986	3000250
intrastriatal injection of dl-2-amino-5-phosphonovaleric acid (ap-5) induces sniffing stereotypy that is antagonized by haloperidol and clozapine.	dl-2-amino-5-phosphonovaleric acid (ap-5), which blocks glutamatergic transmission at the nmda-preferring receptor, was injected into the antero-dorsal striatum of rats. ap-5-induced behavioural changes were assessed i) using a stereotypy rating scale and ii) using an experimental chamber designed to quantify sniffing. in both behavioural situations it was shown that ap-5 (10 micrograms/0.5 microliter) induced continuous intensive sniffing similar to that induced by small doses of systemically a ...	1986	2876450
aminergic neurotransmitter and water content changes in rats after transient forebrain ischemia.	we have studied changes of cerebral monoamine metabolism and water content, during recirculation following global transient ischemia (20 min) using the four-vessel occlusion model in rats. levels of monoamines and their metabolites were determined in cortex, striatum, hippocampus, and hypothalamus. water content was evaluated by weight and by the analysis of t1 and t2 relaxation times in 1h-nuclear magnetic resonance. norepinephine levels decreased; 3,4-dihydroxyphenylethylamine, 3,4-dihydroxyph ...	1986	2430056
aminergic neurotransmitter and water content changes in rats after transient forebrain ischemia.	we have studied changes of cerebral monoamine metabolism and water content, during recirculation following global transient ischemia (20 min) using the four-vessel occlusion model in rats. levels of monoamines and their metabolites were determined in cortex, striatum, hippocampus, and hypothalamus. water content was evaluated by weight and by the analysis of t1 and t2 relaxation times in 1h-nuclear magnetic resonance. norepinephine levels decreased; 3,4-dihydroxyphenylethylamine, 3,4-dihydroxyph ...	1986	2430056
second-generation cephalosporins.		1986	3081544
leu-3/t4 expression on epidermal langerhans cells in normal and diseased skin.	recent evidence exists that the expression of the leu-3/t4 antigen is not restricted to thymus-derived lymphocytes but can also be detected on mononuclear phagocytes and epidermal langerhans cells (lc). when searching for the presence of leu-3/t4 antigen-bearing cells in tissue sections of a variety of inflammatory and neoplastic skin disorders, we observed quantitative and qualitative differences in the intensity of anti-leu-3a labeling of epidermal dendritic cells. reasoning that leu-3/t4 expr ...	1986	3091703
immunological relationship among glycogen-protein complexes of different species.	glycogen-protein complexes from the muscles of celerio euphorbiae and horse as well as from the livers of frog, carp and man were isolated and used as antigens. after immunization of rabbits antisera were obtained from which fractions of immunoglobulins were isolated. antibodies were used in agar immunodiffusion tests and in quantitative reaction of immunoprecipitation with glycogens. the immunoprecipitation test proved the occurrence of quantitative differences in cross reaction of complexes wi ...	1986	3109350
topical ocular drug delivery: recent developments and future challenges.	existing ocular drug delivery systems are fairly primitive and inefficient, but the stage is set for the rational design of newer and significantly improved systems. the focus of this review is on recent developments in topical ocular drug delivery systems relative to their success in overcoming the constraints imposed by the eye and to the improvements that have yet to be made. in addition, this review attempts to place in perspective the importance of pharmacokinetic modeling, ocular drug phar ...	1986	3332284
society for pediatric radiology john caffey award. mr appearance of blood and blood products: an in vitro study.	there are conflicting reports on the appearance of blood and blood clot as seen in the human body by mri. this study was designed to show the in vitro mr signal intensity of human blood products in the fresh state and to evaluate the serial mri changes that occur over time (2 weeks). t1 relaxation times were also measured. anticoagulated whole blood, plasma, serum, white blood cell concentrates, platelet concentrates, lysed red cells, red cell concentrates, and blood clot were studied. the resul ...	1986	3486571
suppression of plasma aldosterone during stimulation of cardiopulmonary mechanoreceptors in man.		1986	3553842
muscarinic cholinergic receptor subtypes in the rat brain. i. quantitative autoradiographic studies.	the binding characteristics of n[3h]methylscopolamine ([3h]nms) to slide-mounted tissue sections were studied using quantitative autoradiography. binding of [3h]nms was saturable, reversible and of high affinity (kd = 0.26 nm). the inhibition of [3h]nms binding produced by several muscarinic agonists and antagonists was analyzed in 29 discrete brain regions by constructing complete displacement curves. comparison of ic50 values obtained both biochemically and by autoradiography demonstrated a ve ...	1986	3942874
a functional organization of on and off pathways in the rabbit retina.	intracellular electrophysiological recordings were obtained from amacrine and ganglion cells in an isolated, superfused retina-eyecup preparation of the rabbit. cells were characterized physiologically, after which cell-staining was accomplished by intracellular iontophoresis of hrp. a computer-assisted image-processing system was used to study the dendritic stratification pattern of hrp-labeled neurons within the inner plexiform layer (ipl). our results support the concept that the ipl is funct ...	1986	3944611
on dying more than one death.	death (with a capital d) can best be understood as a series of distinct but related deaths. for example, a pregnant woman was found to be brain-dead but her vital functions were artificially sustained for nine weeks until her fetus could be delivered, after which the machines were removed and she died a second, conceptually distinct death. this procedure is probably justifiable, but any legislation or policy regarding such cases should be flexible and should require consent.	1986	3957650
brain macrophages in human cortical contusions as indicator of survival period.	the aim of this study was to establish a morphologic time scheme with which cases of cerebral contusion with unknown survival periods can be dated. our study of 275 cases was limited to qualitative and quantitative changes in macrophages. the appearance of macrophages and their distribution as well as their content of neutral fat, esterified cholesterol, erythrocytes, siderin, hematoidin, and ceroid were correlated with the survival period. for each cytologic criterium, the observation period, d ...	1986	3710334