Publications

[e-antibodies in the sera of animals inoculated against plague and pseudotuberculosis].		1978	371269
influence of hyperglycemia on survival after hemorrhagic shock.	terms such as "insulin resistance" and "glucose intolerance" applied to shock-induced hyperglycemia suggest that this state may prejudice survival. however, our data indicate that posthemorrhage hyperglycemia improves short-term survival. rabbits, either fed until the experiment or fasted for 24 hours, were shocked by rapid removal of 25% of their blood volume (bv) measured by 131ihsa. during the next 60 minutes, blood pressure (bp) was recorded, and the following variables were measured every 1 ...	1978	262089
[allergic reactivity and the hypothalamus].		1978	355990
different histologic types of mesenteric lymphadenitis in yersinia pseudotuberculosis type i and type ii infection.		1978	356012
[outbreak of yersinia pseudotuberculosis (y. rodentium) in a family in argentina].		1978	358302
mechanisms of headache.	it is thus evident that the mechanisms of headache differ widely from one syndrome or symptom complex to another. both intracranial and extracranial structures may be involved. knowledge of headache mechanisms is indispensable to the clinician charged with the management of his patient's complaints. such knowledge should guide the investigations which may be required, and the treatment program to be instituted. as knowledge of headache mechanisms is broadened and our current concepts are altered ...	1978	351305
postdiarrheal arthropathy of yersinia pseudotuberculosis.	two patients with acute gastroenteritis in whom polyarthritis subsequently developed were found to have positive serologic results for yersinia pseudotuberculosis. with resolution of the arthropathy the antibody titres decreased. while the patient without the histocompatibility antigen hla-b27 had an acute, self-limited arthritis, the patient with this antigen had a more chronic arthritis. serologic typing and stool culture for y. pseudotuberculosis should be done in cases of postdysenteric arth ...	1978	343903
["yersinia pseudotuberculosis" in a case of mesenteric lymphadenitis (author's transl)].	an eleven-year old girl's case of an inflammatory process of the right lower abdomen is described, with a positive agglutination reaction to "y. pseudotuberculosis", serotype i-a. the surgical operation disclosed a normal coecal appendix as well as a mass of clustered ganglionar adenopathies, exclusively located in the ileo-coecal junction. histologic findings were a pulpar and follicular hyperplasia with mastocytes accumulation and metachromatic staining of capsule and connective tissue. from h ...	1978	365033
[role of antibodies in protection from pseudotuberculous infection and intoxication].	lethal doses of virulent pseudotuberculosis bacilli and antipseudotuberculosis sera of different specificity were injected to albino mice simultaneously. a high neutralizing activity of antibodies against pseudotuberculosis intoxication was demonstrated. the type-specific antibodies proved to protect the mice from the toxins of the homologous types of the microbe only. group antibodies of plaque antiserum and serum procured from the pseudoteburculosis convalescent produced a cross antitoxic acti ...	1978	358704
[dry erythrocyte pseudotuberculosis diagnosticum].		1978	352061
alterations in the expression of the cytomegalovirus-induced cytopathogenic effect in fibroblasts by aflatoxin b1.	aflatoxin b1 has been shown both to promote and to alter the expression of the cytopathogenic effect observed when human fibroblasts are challenged with human cytomegalovirus (cmv). although the cells become round, as is the characteristic effect of this virus on fibroblasts, multinucleate cells are seen to arise from cell fusion within 48 h after virus addition.	1978	218602
a comparison of the biological and biochemical properties of 1-(4-amino-2-methylpyrimidin-5-yl)methyl-3-(2-chloroethyl)-3-nitrosourea and 2-[3-(2-chloroethyl)-3-nitrosoureido]-d-glucopyranose.	1-4-amino-2-methylpyrimidin-5-yl)methyl-3-(2-chloroethyl)-3-nitrosourea (acnu) is a water-soluble nitrosourea that has produced delayed hematological toxicity in man during phase 1 clinical trials. acnu has in vitro alkylating activy 40% less than that of 2-[3-(2-chloroethyl)-3-nitrosoureido]-d-glucopyranose (chlorozotocin) but shares the property of negligible carbamoylating activity with the latter compounds. acnu is highly active against murine l1210 leukemia. however, the maximum therapeutic ...	1978	145314
yersinia enterocolitica and pseudotuberculosis infection in children.	the clinical symptoms of infections with y. ent. and pseudotub. are of a different nature. whether the infection becomes apparent in form of a pseudo-appendicitis, enterocolitis or a typho-septic disease does apparently not only depend on the type of pathogens but also on the children's condition with regard to their resistance. all forms mentioned are observed in case of infections with yersinia pseudotuberculosis as well as in case of infections with yersinia pseudotuberculosis as well as in c ...	1978	343179
influence of fibrinogen degradation products (fdp) on the atpase activity in the rat heart.	influence of fibrinogen degradation products (fdp) on the atpase activity in the rat heart. acta physiol. pol., 1978, 29 (2): 185--187. the influence of dialysable fibrinogen degradation products (fdp) on the atpase activity was studied. it was found that fdp augment the mg(2+)-- dependent atpase and slightly decrease the (na+--k+) dependent atpase in the rat heart. it is concluded that biological activity of examined peptides depend on other mechanisms than the direct effect on atpase in the he ...	1978	148831
formylation of initiator trna methionine in procaryotic protein synthesis: in vivo polarity in lactose operon expression.	eucaryotic and procaryotic organisms differ in two aspects of their translation machinery: polycistronic messengers are expressed as a sequence of individual proteins only in procaryotes, and the initiation of protein synthesis proceeds with an initiator trna which is found to be modified (formylated) in procaryotes and not in eucaryotes. in the present study, we show that formylation is required in vivo for the coordinate expression of the escherichia coli lactose operon. our experiments are co ...	1978	98518
[problems of the epidemiology of pseudotuberculosis in leningrad].		1978	148740
epilepsy, attentiveness and consciousness: recent contributions from behavioral and physiological investigations. a summary and commentary.		1978	108075
specific alpha-adrenergic receptor desensitization in vascular smooth muscle.	specific desensitization of vascular tissue to norepinephrine was studied using an open-ring-type strip preparation of rabbit aorta. aortae were taken from untreated, reserpine-pretreated (0.1 mg/kg/day; 3, 5, or 7 days) and 6-hydroxydropamine-pretreated (50 mg/kg; 3 or 7 days before sacrifice) rabbits. aortic strips from the pretreated rabbits were supersensitive to norepinephrine. subsequent to obtaining the first dose-response curve for norepinephrine, aortic strips were less sensitive to nor ...	1978	205285
transformation of african green monkey kidney cells with the rf strain of human papovavirus bkv.		1978	206005
kinetics of lipid--protein interactions: interaction of apolipoprotein a-i from human plasma high density lipoproteins with phosphatidylcholines.		1978	207309
differential effects of isolated lipoproteins from normal and hypercholesterolemic rhesus monkeys on cholesterol esterification and accumulation in arterial smooth muscle cells in culture.	whole serum obtained from hypercholesterolemic rhesus monkeys was found to stimulate cholesterol esterification and cholesteryl ester accumulation in rhesus monkey arterial smooth muscle cells in culture to a significantly greater extent than normocholesterolemic serum. this was true even when the cholesterol concentration of the culture medium was equalized. isolation and characterzation of the low density lipoproteins (ldl) from rhesus monkeys indicated that the ldl from hypercholesterolemic a ...	1978	208631
[septicemia cause by yersinia pseudotuberculosis. apropos of 2 case reports].		1978	209546
isolation, characterization, and synthesis of a corticotropin-inhibiting peptide from human pituitary glands.	a corticotropin-inhibiting peptide (cip) has been isolated from human pituitary extracts. it consists of 32 amino acids with a proposed sequence identical to residues 7--38 of corticotropin (acth). the peptide has been synthesized by the solid-phase method. the melanotropic activity of the peptide is estimated to be 30% of the potency of acth. it is devoid of corticosteroidogenic activity but is able to inhibit acth-stimulated corticosterone production in isolated rat adrenal cells.	1978	212744
conversion of rubratoxin b to the carboxylic acid derivative and its effect on adenosine triphosphatase activity and toxicity to mice.		1978	213356
functional studies on crosslinked bovine cytochrome c oxidase.		1978	202495
cytodifferentiation in the acute myeloblastic leukemias of man.	correlation analysis of numbers of colony-forming progenitor cells was used as an approach to the quantitation of human pluripotent stem cells. marrow specimens were obtained from 24 patients with untreated acute myeloblastic leukemia, 22 patients under treatment, and 29 patients with no hematologic malignant disease. three classes of progenitor cells were assayed: burst-forming units dependent on erythropoietin (bfu-e), colony-forming units dependent on erythropoietin (cfu-e), and granulopoieti ...	1978	271747
[attempts to demonstrate and identify avian adenoviruses by an immunofluorescence method].	a specific conjugate of a hyperimmune serum, obtained from rabbits with the use of the reference phelps-celo strain, was employed in a direct immunofluorescence method to investigate more than 320 lamelles with cell cultures infected with 4 field celo virus strains and the reference phelps-celo strain. it is stated this method is specific and prompt for the early diagnosis and identification of adenoviruses (celo viruses).	1978	210562
sensitivity of yersinia pseudotuberculosis and yersinia enterocolitica strains to a 6-beta-amidino penicillanic acid derivative.		1978	211112
[intestinal yersiniosis: 25 cases of infections with yersinia pseudotuberculosis and yersinia enterocolitica (author's transl)].	yersinia infections in 16 adults and 9 children are reported. 15 cases were caused by yersinia pseudotuberculosis, 8 of them were proved by serological findings. in 4 cases the infection by yersinia pseudotuberculosis was likely, in 3 other cases possible only. real infections caused by serotype iv are demonstrated too. furthermore there were 10 cases caused by yersinia enterocolitica, 3 of them were proved by bacterial, the other ones by serological findings. both germs caused identical symptom ...	1978	207960
[the manufacture of nystatin-gelatin foils for the treatment of denture stomatitis].	the authors describe the formula and the manufacture of nystatin-gelatin foils that are a new dosage form for local application in case of denture sore mouth induced by candida albicans. it is pointed to the requirements that a pharmaceutically used gelatin should meet. furthermore, the authors discuss biopharmaceutical aspects of the nystatin-gelatin foil.	1978	273327
different secretion patterns of active and inactive renin in man.	1. in plasma samples from normal subjects and patients with untreated essential hypertension, the concentration of inactive renin (as measured after acidification) was on average 4-5 times higher than the concentration of active renin (as measured without acidification).2. plasma angiotensin ii concentration was correlated to active renin but not to inactive renin. 3. a hyperacute stimulation induced by infusion of saralasin resulted in a marked rise of active renin, whereas inactive renin remai ...	1978	282041
[technic for the detection of salmonella in dehydrated food-stuff].		1978	262971
modified peptidoglycan transpeptidase activity in a carbenicillin-resistant mutant of pseudomonas aeruginosa 18s.	a carbenicillin-resistant mutant of pseudomonas aeruginosa 18s was found to possess peptidoglycan transpeptidase activity significantly more resistant to inhibition by benzyl penicillin, ampicillin, carbenicillin, and cephaloridine than that of the parent strain. the mutant was more resistant than the parent strain to all of the beta-lactam antibiotics tested, and 50% inhibition values for these compounds against membrane-bound model transpeptidase activity paralleled this increase. the resistan ...	1978	100051
localization of prostaglandin synthetase in chicken epiphyseal cartilage.	prostaglandin synthetase activity in high-speed particulate fractions of chick epiphyseal cartilage has been characterized with respect to cofactor requirements, ph optimum, buffer-ion effects, types of prostaglandins formed, and the distribution of prostaglandin synthetase activity in zones of the epiphyseal plate. direct homogenization of cartilage was found to be more efficacious than releasing chondrocytes by enzymatic digestion for preparation of prostaglandin synthetase, a homogenization t ...	1978	108004
ultraviolet light-induction and photoreactivation of thymine dimers in a cyanobacterium, anacystis nidulans.	partially photoreactivable mutant of anacystis nidulans demonstrates partial photorepair of thymine dimers. the wild type which is completely photoreactivable at the conditions studied shows higher level of thymine dimer photolysis.	1978	100072
[origin of a mitogrenic factor for cultivated macrophages (imf: inflammatory mitogenic factor) found in exudates of non-specific acute inflammation].	the mitogenic activity of inflammatory exudate obtained from irradiated rats is reduced. after transfer of bone marrow syngeneic cells into irradiated rats this mitogenic activity is further decreased, while after transfer of thymic cells it is increased. it is postulated that the mitogenic activity of inflammatory exudate could be related to thymic cells and that t lymphocytes may be involved in non specific-inflammatory reactions.	1978	100246
amino acid sequence alignment of bacterial and mammalian pancreatic serine proteases based on topological equivalences.	the three-dimensional structures of the bacterial serine proteases sgpa, sgpb, and alpha-lytic protease have been compared with those of the pancreatic enzymes alpha-chymotrypsin and elastase. this comparison shows that approximately 60% (55-64%) of the alpha-carbon atom positions of the bacterial serine proteases are topologically equivalent to the alpha-carbon atom positions of the pancreatic enzymes. the corresponding value for a comparison of the bacterial enzymes among themselves is approxi ...	1978	96920
role of pyridoxine in the metabolism of putrescine in the rat.	1. the ability of rats to metabolize radioactive putrescine to 14co2 in vivo has been studied. 2. animals made deficient in pyridoxine exhibit a significantly lower rate of catabolism of the diamine. 3. there dose not appear to be an important interaction between the effects of the deficiency and those stemming from treatment of the animals with the diamine oxidase inhibitor aminoguanidine. 4. these results favour the concept of a role of pyridoxal cofactor in the metabolism of diamines, presuma ...	1978	96921
analysis of cytotoxic mechanisms induced by minor histocompatibility antigens in the mouse.		1978	96941
influences of physical conditioning and deconditioning on coronary vasculature of dogs.	to investigate the effects of physical conditioning and deconditioning on the coronary vasculature, eight dogs were exercised by treadmill running. five dogs were deconditioned by confinement in cages following the conditioning period. a technique was developed and validated for measuring circumflex coronary artery diameter from magnified projections of standardized coronary angiograms. myocardial capillary density, perimeter, and basement membrane thickness were determined from electron microsc ...	1978	101496
dominant constitutive mutations in malt, the positive regulator gene of the maltose regulon in escherichia coli.		1978	101676
studies on virus-inhibiting substances of bacterial origin. iv. antiviral substances extractable from streptococcus faecalis: its in vivo effect.		1978	101714
[effect of reserpine on the formation of 9,10-dimethyl-1,2-benzanthracene induced tumors in pinealectomized and thymectomized rats].	after reserpine treatment the incidence of dimethylbenzanthracene-induced tumors was found to be significantly higher in pinealectomized rats than in intact or thymectomized ones. a very high rate of dmba-leukemia was observed in immune-deficient pinealectomized rats after reserpine administration. it is therefore suggested that the neuroendocrine disturbances due to removal of the pineal gland in the newborn animals, are latent and become evident after reserpine administration as reflected in a ...	1978	101920
a microagglutination test for yersinia enterocolitica infection: recognition of multiple serotypes in experiments with stained suspensions of serotype o5,27.	when suspensions of yersinia enterocolitica were stained with triphenyl-tetrazolium chloride (ttc) their antigenic specificity, as determined by tube and microtitre-plate agglutination tests, was altered. thus, a ttc-stained suspension of serotype o5,27 detected antibodies to nine o serotypes of y. enterocolitica in sera from experimentally infected animals but did not cross-react with antisera to organisms of five other unrelated genera including brucella. the same suspension did, however, cros ...	1978	98635
the effects of sodium nitroprusside and trimethaphan camsylate on cerebral blood flow in rhesus monkeys.	hemispheric cerebral blood flow was measured in the rhesus monkey before and after infusion of the hypotensive agents sodium nitroprusside and trimethaphan camsylate. the intracarotid injections of 133xe was utilized, and flow was calculated by the "flow initial" technique. cerebral blood flow did not change significantly with the administration of trimethaphan camsylate. however, with a small reduction in blood pressure (10.6%) during the administration of sodium nitroprusside, the cerebral blo ...	1978	98729
phosphate transport in the proximal convolution of the rat kidney ii. effect of extracellular ca2+ and application of the ca2+ ionophore a 23187 in chronic ptx animals.	proximal inorganic phosphate (pi) transport was evaluated using the standing droplet method with simultaneous microperfusion of the peritubular blood capillaries. in chronic parathyroidectomized (ptx) rats addition of 3 micron of the ca2+ ionophore a 23187 to the luminal perfusate had no effect on the pi transport, although the isotonic fluid reabsorption was reduced by 20%. when the ca2+ concentration in the perfusates was raised from 1.5mm to 3.0mm the the reabsorption did not change signific ...	1978	98754
vascular dynamics of an experimental cerebral arteriovenous shunt in the primate.	an arteriovenous fistula which shunted arterial blood from the circle of willis to the internal jugular vein was created in ten monkeys. continued patency of the shunt was confirmed angiographically. cerebral blood flow measurements were then obtained with the shunt both open and occluded. flow was also determined in response to elevations of systemic arterial pressure and raised arterial carbon dioxide tensions (paco2), again with the shunt both patent and occluded. in addition, flow through th ...	1978	98854
[some contributions by chemical carcinogenesis--what is the animal model of human cancer? (author's transl)].		1978	99767
constant and flickering light stimulations produce similar effects on rna content in visual cells.	adult male rats were illuminated for 2 h with a constant or flickering light of 40 lx intensity; frequency of flickering was 2 hz. by means of two-wave-length visible cytospectrophotometry of gallocyanin-stained sections, it was shown that the light stimulation resulted in a marked rna accumulation in retina ganglion neurons and in the neurons of all the cell layers of visual cortex (with the only exception of the layer vi). in the cells of perineuronal glia, a decrease of the rna content per ce ...	1978	107713
dietary lactose and the aetiology of human small-intestinal hypolactasia.		1978	103781
on the interactions of yersinia strains and cell cultures.	comparative investigations were carried out on the dynamics of invasion of cell cultures by strains yersinia pestis ev and yersinia pseudotuberculosis treated vitally with petroleum ether. it was established that the invasiveness of the strains studied was related to the presence of chemical structures of the bacterial surface sensitive to the action of either and whose synthesis was temperature dependent. the penetration and initial stages of intracellular multiplication of the yersinia were ac ...	1978	104477
ultrastructural hepatic changes by carbamate pesticide (sevin) in rats.		1978	98323
the pattern of sporulation in anabaena circinalis and comments on the role of heterocysts in sporulation in blue-green algae.	cells between two intercalary heterocysts differentiate at random into spores in a. circinalis. one or more cells, which fail to transform into spores, are present between the two adjacent spores, and these cells disorganize later. a critical c:n ratio regulates sporulation and heterocyst formation. during sporulation the reductive ability of the heterocyst gradually diminishes. it is concluded on the basis of this and other evidence that sporulation is regulated by interactions between heterocy ...	1978	97869
detection accuracy in chest radiography.	the detection accuracy of the diagnostic radiologist is important in everyday medical decision making. however, little work has been done relating the detection accuracy of the radiologist to the quality of the image. this study, using a thorax and lung phantom, simulated tissue-equivalent 6.4 mm lesions, and a 183 cm source-to-image distance, shows that the detection accuracy is not dependent on the focal spot size (over a range of 0.3-2.0 mm). however, the false positive rate increases when us ...	1978	98003
[repeated microcycle in bacillus cereus].		1978	96318
effects of ethanol on pregnant rats and their offspring.	pregnant rats were intubated with either 1.0 or 2.0 g/kg of ethanol daily throughout gestation. pair-fed vehicle-treated, and nontreated rats fed ad libitum, served as control groups for ethanol-treated animals. ethanol treatment reduced food and water consumption and attenuated the gain in body weight of pregnant animals relative to nontreated animals fed ad libitum. litter size, litter weight, and the mean weight per pup were reduced in both the ethanol-treated and pair-fed control groups. the ...	1978	96469
[observation on the antigenic affinity of leptospira and brucella in the serological examination of cattle].	36,9% bovine serums which showed a non-specific reaction in examination for brucellosis had titre greater than or equal to 1:400 leptospirosis agglutinins. 15.1% of the serums showed a positive reaction (greater than 1:800), mostly those against l. sejroe and l. grippotyphosa. the cross reactions, found in individual cases within up to 39 days since the first reaction to brucellosis in cattle may signalize early leptospira infections.	1978	96568
differentiation of mycobacteria by "in vivo" and "in vitro" delayed hypersensitivity reactions.	guinea pigs were sensitized with heat killed m. tuberculosis, m. kansasii, m. scrofulaceum, and m. avium-intracellulare. purified protein derivatives (ppds) prepared from each of these organisms were tested for delayed type hypersensitivity by lymphocyte transformation, macrophage migration, and mantoux type skin sensitivity tests. the homologous reactions were consistently more intense than heterologous reactions in all three procedures. the skin test procedure was more sensitive than either in ...	1978	98814
effect of growth environment on pseudomonas aeruginosa killing by rabbit polymorphonuclear leudocytes and cationic proteins.	pseudomonas aeruginosa grown in a chemostat under carbon- and magnesium-limited conditions showed varying resistance to killing by rabbit peritoneal exudate polymorphonuclear leukocytes. slow-growing (d = 0.05 h-1), magnesium-limited cells were significantly more resistant to the lethal effects of the phagocytes than were fast-growing magnesium-limited cells and carbon-limited cells (d = 0.05 h-1 and d = 0.5 h-1, respectively). the resistance of magnesium-limited cells to killing by cationic pro ...	1978	97227
nonrebreathing valve for spontaneously breathing or mechanically ventilated animals.	the design of a small dead space, nonbreathing valve suitable for use in small laboratory animals is presented. the design overcomes previous problems of condensation occurring at valve leaflets, and allows ongoing collection of expired gases should the animal require mechanical ventilation. the valve apparatus performs reliably when in operation for several hours at a time with a variety of small animals.	1978	97251
antimicrobial agents as preservatives in pharmaceutical and cosmetic products. agents as preservatives in eye-drops and contact lens solutions.		1978	97255
amino acid sequence of beta-galactosidase. viii. sequence of the nh2-terminal segment, cnbr peptides 1 to 9, residues 1 to 377.	the amino acids in 9 cyanogen bromide peptides have been placed in sequence starting from the nh2 terminus. the peptides account for residues 1 to 377 of the whole protein and include the largest (cnbr7, 119 residues) and the smallest (cnbr1, 2 residues) of the cyanogen bromide peptides. this region contains only 3 of the 20 lysine residues in the polypeptide chain. a high proportion of charged groups are present (28 of 66 arginine, 28 of 60 glutamic acid, and 24 of 65 aspartic acid residues).	1978	97295
[reservoirs and wild vectors of trypanosoma cruzi. lxviii: infection of mammals by oral route].		1978	97735
sexual behavior and hormone levels during the menstrual cycles of rhesus monkeys.		1978	108191
[pseudomonas aeruginosa infection in patients with thermal lesions].		1978	98664
[chronic oral cadmium load in sheep. toxicological and pathomorphological studies].		1978	106587
isolation of neurospora crassa-bovine l-glutamate dehydrogenase hybrids [proceedings].		1978	154423
isolation of neurospora crassa-bovine l-glutamate dehydrogenase hybrids [proceedings].		1978	154423
uv versus chemical polymerization of glycol methacrylate (gma) in enzyme histochemistry.	the influence of the mode of polymerization of gma on the enzyme activities of differently fixed rat livers was studied. it was found that with increasing time of uv-polymerization several enzyme activities were inhibited whereas chemical polymerization was comparatively less harmful. the histochemical reactivity of substrates such as glycogen was not impaired by the mode of polymerization, which is in contrast to the increased basophilia of dna and rna after uv-polymerization.	1978	107707
[preparation of extracellular ribonuclease from bacillus subtilis].	the paper describes a method for isolating alkaline ribonuclease from the culture liquid bacillus subtilis kp 349 which involved: submerged cultivation of the producer on complex and synthetic nutrient media with optimized rnase activity, acid treatment of the total culture liquid, and filtration through perlite. further treatment may include either spray drying of the culture liquid filtrate or its concentration in a vacuum evaporator, dialysis of the concentrate against distilled water, and d ...	1978	107517
relative fat-carbohydrate efficacy in parenteral nutritional support.		1978	122624
the physiological disposition of the anti-tussive agent, 1,2,3,4a,9b-hexahydro-8,9b-dimethyl-4-[3-(4-methylpiperazin-1-yl)propionamido]dibenzofuran-3-one dihydrochloride azipranone, in man, rat, dog and baboon.	1. the absorption, tissue distrigution, elimination and biotransformation of the anti-tussive agent azipranone labelled with 14c have been investigated after oral dosing to rat, dog, baboon and man and parenteral administration to rat and baboon. 2. levels of radioactivity in plasma were maximal within 20 min of dosing in the rat and after 1-2 h in the remaining species. the concn. declined thereafter with a half-life estimated at 1, 3-4 and 18-24 h for rat, dog, and baboon and man respectively. ...	1978	96617
[capsule formation in bac. anthracis on a carbon medium].		1978	98898
[some aspects relating to the aflatoxin generation during the self-heating of cereals].	in a stored batch of grain which was already affected by mould-formation tests were carried out with the known aflatoxin producer aspergillus flavus. a significantly lower aflatoxin production ensued if the mould growth was not connected with self-heating of the stored product. however, in conformity with increasing mould formation the germinating power was adversely affected and the significant signs (fatty acid number, reductive and none-reductive sugars) were influenced in the grain, irreleve ...	1978	98933
pituitary responsiveness to lhrh and trh in adolescent girls.	puberty is characterized by a progressive maturation of the hypothalamus-pituitary gonadal axis which, in girls results in menarche. the first menstrual cycles are usually irregular and anovulatory, and the subtle positive and negative regulation of sex steroids on the hypothalamus-pituitary axis has probably not reached adult maturity. an investigation has been carried out in 99 normal adolescent girls, divided into 3 groups: 1-2, 3-4 and 5 years after menarche, by measuring basal hormonal valu ...	1978	96896
[radioimmunological aspects of neuropeptides].	immunological aspects of neurosecretory peptides are relevant to antibody generation, labelling of peptides for radioimmunoassays and in particular the metabolism of neuropeptides. antibodies were generally produced by adsorption or polymerization (using different approaches and various coupling agents) of peptides with intrinsic antigenic molecules preceding their administration to recepient animals (rats, guinea pigs, rabbits and sheep) with adjuvants. antibodies were also obtained by injectin ...	1978	96897
effect of a staphylococcin on neisseria gonorrhoeae.	phage group 2 staphylococcal strain ut0002 contains a large 56s virulence plasmid with genes that code for both exfoliative toxin and a specific staphylococcin termed bac r(1). four penicillinase-producing strains and three penicillin-susceptible strains of neisseria gonorrhoeae were killed by bac r(1). after 30 min of growth of the penicillin-resistant tr1 strain in 62.5 arbitrary units of bac r(1) per ml, loss of viability was approximately 90%, and, after 5 h, an approximately 99.99% loss of ...	1978	100049
uk-18892, a new aminoglycoside: an in vitro study.	uk-18892 is a new aminoglycoside antibiotic, a derivative of kanamycin a structurally related to amikacin. it was found to be active against a wide range of pathogenic bacteria, including many gentamicin-resistant strains. the spectrum and degree of activity of uk-18892 were similar to those of amikacin, and differences were relatively minor. uk-18892 was about twice as active as amikacin against gentamicin-susceptible strains of pseudomonas aeruginosa. both amikacin and uk-18892 were equally ac ...	1978	100050
single unit analysis of 'mirror foci' in chronic epileptic monkeys.		1978	96914
phycobiliprotein synthesis in protoplasts of the unicellular cyanophyte, anacystis nidulans.	stable and metabolically active protoplasts were prepared from the unicellular cyanophyte, anacystis nidulans, by enzymatic digestion of the cell wall with 0.1% lysozyme. the yield of protoplasts from intact algal cells was approx. 50%. incorporation of l-[u-14c]leucine into cold trichloroacetic acid-insoluble material from protoplasts preparations was linear for 1.5 h and continued for an additional 2.5 h. incorporation of radiolabeled leucine into hot trichloroacetic acid-insoluble material fr ...	1978	96857
[formation of cutaneous nerve trunks in the chick. ultrastructural and quantitative analysis].	in chick skin structuration of nervous trunks takes place at 14-15 days of incubation, at the time of formation of the adult pattern of cutaneous innervation. at this same stage, myelogenesis begins, but develops mainly after hatching: only 4% of axons are myelinated at hatching, 40% in 6-week old chickens and 60% in adults. this "critical" stage (14-15 days of incubation) apparently corresponds to the stabilization of cutaneous nerve supply.	1978	96985
external neuroanatomy of old world monkeys (cercopithecoidea).		1978	97050
incorporation of amino acids by isolated submitochondrial fractions of lactating goat mammary gland in vitro.	incorporation of amino acids by mitochondria and its subfractions from mammary gland of the goat during lactation was studied in vitro. assessment of distribution of radioactivity incorporated by intact mitochondria into its subfractions revealed maximum specific activity in the inner membrane. during lactation the inner membrane of mitochondria exhibited further stimulation in such incorporation. matrix was the next active fraction whereas outer membrane and peripheral space had negligible radi ...	1978	101564
immunochemical studies of the inactivation of aspartate transcarbamylase by stationary phase bacillus subtilis cells. evidence for selective, energy-dependent degradation.	the aspartate transcarbamylase of bacillus subtilis is stable in exponentially growing cells, but undergoes rapid, energy-dependent inactivation when growth is inhibited by nutrient depletion or addition of antibiotics or other inhibitors of metabolism. this inactivation has been analyzed by a variety of immunochemical techniques, including direct and indirect immunoprecipitation of extracts of cells labeled with 3h-amino-acids, microcomplement fixation, and neutralization of enzymatic activity. ...	1978	97299
malignant transformation of a mouse epithelial cell line with polycyclic aromatic hydrocarbons.		1978	97564
effects of various divalent cations on the survival of neisseria gonorrhoeae in liquid media.	the effect of various concentrations of divalent cations on survival of gonococci in liquid medium was studied. the growth of neisseria gonorrhoeae was inhibited by manganous chloride in concentrations above 1 x 10(-5)mol/l while the growth of control organisms such as neisseria meningitidis and escherichia coli was not inhibited by the same salt even at 1 x 10(-2)mol/l. copper sulphate, cobaltous nitrate, nickel chloride, and zinc sulphate also had deleterious effects on gonococci. magnesium ch ...	1978	98204
characteristics of pr5, a lipid-containing plasmid-dependent phage.	an extensive characterization of plasmid-dependent phage pr5 isolated from sewage has been carried out. the phage has a head diameter of 65--68 nm, is isometric with a double-layered capsid, and a minority possess tails. it adsorbs to many but not all types of bacteria possessing p, n, or w plasmids. the phage contains 20% lipid, 15.1% dna, and 64.9% protein by weight and has a buoyant density of 1.265 g/ml in cscl. the dna is double-stranded with a g + c content of 49% and a molecular weight of ...	1978	98225
cellular uptake, transport, and macromolecular binding of benzo(a)pyrene and 7,12-dimethylbenz(a)anthracene by human cells in vitro.		1978	98231
effect of vitamin a acid on the growth of keratinocytes in culture.	the effect of vitamin a acid on the culture of guinea pig ear keratinocytes was investigated. use of this agent and treatment of the plastic dishes with collagen solution facilitated attachment and growth. vitamin a acid elicited a wave of dna synthesis which was studied by incorporation of tritiated thymidine and quantitation of cellular dna, particularly during the period 24--45 h after plating. during this period, thymidine incorporation into dna was increased ten-fold by vitamin a acid and s ...	1978	93879
picosecond detection of bchl-800 as an intermediate electron carrier between selectively-excited p870 and bacteriopheophytin in rhodospirillum rubrum relaction centers.		1978	97097
coagulation changes following vasectomy: a study in primates.	thirty vasectomized rhesus monkeys were tested for changes in coagulation factors that might reflect an increased incidence of thrombosis. the results of tests on these monkeys were compared with results of tests on 18 control rhesus monkeys; there were no significant differences between control and vasectomized animals for any of the parameters tested. one vasectomized animal had increased levels of fibrin monomer in his plasma on repeated samples, but no evidence of thrombosis on postmortem ex ...	1978	97098
comparison of effects of normal rabbit sera and anti-cock sperm sera on rabbit sperm, including comparison of effects on the sex ratio.		1978	96880
[sarcocyst resistance to certain factors].		1978	97852
5-thio-d-glucose is an acceptor for udp-galactose : d-glucose 1-galactosyltransferase.		1978	96819
regulation of the in vitro synthesis of the alpha-peptide of beta-galactosidase directed by a restriction fragment of the lactose operon.		1978	96823
[oesophageal diverticulum in a pony (author's transl)].	a case of oesophageal diverticulum in a pony is reported. the diagnosis was established by clinical and x-ray examination (following administration of a contrast agent) and verified by post-mortem studies. the cause and pathogenesis are discussed.	1978	96547
chelation in metal intoxication. vi. influence of pas and cdta on the excretion of manganese in rabbits given mno2.	the success of p-aminosalicyclic acid (pas) and 1,2-cyclohexylene dinitrilotetraacetic acid (cdta) in the mobilization of manganese from some vital organs and their subcellular fractions of manganese-intoxicated rats, led to the two compounds beng further investigated individually and in combination for their efficacy in influencing excretion of manganese in rabbits given mno2. these chelating agents led to a higher excretion of manganese through faeces than urine. whereas cdta was able to enhan ...	1978	96549
unusual genes at the aminoterminus of human immunoglobulin variants.		1978	96346
variant of stiff-man syndrome provoked by alcohol: case report.		1978	96364
purification and some properties of a neutral muscle pyrophosphatase.	in the water-soluble fraction of rabbit skeletal muscle, at least two types of inorganic pyro phosphatase (ppase) are distinguishable on ion exchange column chromatography. one of them, pyrophosphatase-a (ppase-a), was isolated in an electrophoretically homogeneous form. this enzyme catalyzed the hydrolysis of ppi but not that of other phosphate esters. only mg2+ was required for activity and stability. other cations such as ca2+, co2+, mn2+, and zn2+ had no activating effect. the activity of th ...	1978	25268