Publications

plague in a neonate.	more than half of the cases of plague in the united states are diagnosed in children. in the 1970s, 105 cases were reported, a 350% increase over the 1960s. plague should be considered in the differential diagnosis of children from the western united states who have sepsis, especially those with lymphadenopathy. complications of plague include meningitis, metabolic encephalopathy, abscess, and pneumonia. with appropriate treatment, prompt clinical response usually occurs. careful isolation and e ...	1981	7234765
occurrence of yersinia enterocolitica in wild animals.	yersinia species were isolated from 16 of 495 small wild animals and from 1 of 38 foxes. the animals were trapped in seven regions of hokkaido, japan. of the 17 strains isolated, 9 were yersinia enterocolitica o6; 2 were y. enterocolitica o5a; 1 was y. enterocolitica, o4; 1 was y. enterocolitica o9; 1 was yersinia pseudotuberculosis ivb; and 3 were sucrose-negative strains. yersinia pestis was not isolated. the o6 organism was most prevalent in large red-back mice (clethrionomys rufocanus bedfor ...	1981	7224628
essential virulence determinants of different yersinia species are carried on a common plasmid.		1981	7243971
[immunologic activity of the "murine" toxin of the plague microbe in experiments on animals].		1981	7245966
[ultrastructural characteristics of the l transformation process of the plague microbe].		1981	7260205
[antibiotic sensitivity of strains of the plague microbe isolated from foci in the caucasus and transcaucasia].	antibiotic sensitivity of 91 strains of the plague microbe isolated in armenia, azerbaijan, daghestan, georgia, kabardino-balkaria and the stavropol region in 1977-1979 from the rodents and their ectoparasites was studied with the method of serial dilutions in the hottinger agar. the following antibiotics were tested: streptomycin, erythromycin, tetracycline, methicillin, gentamicin, levomycetin, monomycin, lincomycin, ristomycin, rifampicin, kanamycin, doxycyclin and polymyxin m. all of the str ...	1981	7259143
susceptibility of members of the mastomys natalensis species complex to experimental infection with yersinia pestis.		1981	7264374
methods of quantitative microbiological analyses that support the diagnosis, treatment, and prognosis of human infection.	the microorganisms responsible for the production of an infection may be considered to be in two classes: classical microbes and host-defined microbes. classical microbes are those pathogens which fulfill the koch-henle postulates, and their isolation from a host indicates infection. they are not normally part of the body's normal flora, although they may be acquired by the host and enter into a passive relationship known as the carrier state. examples of this type of microbe are bacillus anthra ...	1981	7273838
antibody response to plague vaccination in humans as assayed by staphylococcal radioimmune precipitation (st-rip) test.		1981	7275993
feline plague in new mexico: report of five cases.	naturally acquired plague was diagnosed in 5 domestic cats. the cats apparently contracted the disease through contact with sylvatic rodents or their fleas in plague-enzootic areas. the diagnosis was confirmed by direct immunofluorescence and isolation of yersinia pestis on culture of abscess material. abscess formation, lymphadenitis, lethargy, and fever were consistent clinical findings.	1981	7341569
delayed-type hypersensitivity and acquired resistance to plague in mice immunized with killed yersinia pestis and immunoregulators.	a simple reproducible footpad assay of delayed-type hypersensitivity (dth) to yersinia pestis was studied in mice immunized with 5 x 10(7) heat killed (hk) y. pestis alone or in conjunction with freund's complete adjuvant (fca), cyclophosphamide (cy), bcg, or both cy and bcg. the footpad reaction elicited with 5 x 10(6) hk y. pestis was shown to peak at 24 hr, was transferable with immune t lymphocytes but not with serum and had the classical dth histology, the highest level of dth occurred 6 or ...	1981	7028602
[characteristics of fc igg receptors on the surface of formalinized sheep erythrocytes].	the binding of igg molecules with sheep red blood cells (srbc) was evaluated by a decrease in the serological activity of hyperimmune horse serum towards pasteurella pestis capsular antigen. as in serological tests based on passive hemagglutination, low concentrations of red blood cells are commonly used, there was no danger of obtaining distorted results due to the nonspecific adsorption of igg on the surface of srbc. but for the objective evaluation of the results obtained in the determination ...	1981	7269902
[spread of yersinia among patients with acute intestinal infections].	during 1979 a large-scale study of fecal samples obtained from patients with acute intestinal infections was carried out with the aim of establishing the presence of yersinia. as a result, 9 y. enterocolitica strains and 7 y. pseudotuberculosis strains were isolated. y. enterocolitica were classified with serovars o8, o3, and o5b and with biovars 2, 3, and 4; y. pseudotuberculosis were classified with serovars 1 and 3. the isolation of yersinia facilitated the identification of the etiological s ...	1981	7269921
[utilization and fermentation of 2-ketogluconate by "enterobacteriaceae" (author's transl)].	two methods were compared: 1) the ability to use 2-ketogluconate (2-kg) as source of carbon and energy in defined medium, and 2) the ability to produce acid by fermentation of 2-kg (0.5 g/100 ml) in peptone water with phenol red. results of growth on, and acid production from, 2-kg were identical. a total of 990 strains was studied. no strain of escherichia coli, shigella (4 species), salmonella (4 sub-genera), yersinia pestis, y. pseudotuberculosis, edwardsiella (2 species), proteus vulgaris, p ...	1981	7235456
plague in brazil during two years of bacteriological and serological surveillance.	in north-east brazil, where plague infection is endemic, bacteriological and serological methods were employed during a two-year period to determine accurately the occurrence of human infection and to define certain epidemiological features of both human and rodent infection. there were 67 confirmed cases of plague, predominantly among males and children. most of these cases occurred in two inland rural plateaux of ceara state. clustering of cases in place and time was common, as was a history o ...	1981	6976228
rapid diagnostic test that uses isocitrate lyase activity for identification of yersinia pestis.	the presence of high levels of isocitrate lyase activity in yersinia pestis grown on blood agar base medium, as compared with low levels of this enzyme in yersinia pseudotuberculosis and yersinia enterocolitica, suggested that the differences in the levels of this enzyme could be used for the presumptive identification of y. pestis. a modified, semiquantitative assay for isocitrate lyase activity is described which requires no expensive instrumentation, utilizes readily available chemicals and s ...	1981	7014615
[characteristics of the cytomorphological and other indices of immunogenesis in guinea pigs vaccinated after the preliminary administration of an erythropoiesis stimulant].		1981	7199240
[serum antibody and splenocyte immunoglobulin receptor affinity in multiply immunized mice].	in the process of repeated immunization of cba mice with soluble pasteurella pestis capsular antigen the concentration of antibodies in the blood increased, but the dynamics of antibody affinity in the serum did not correlate with this process. for the first time the average splenocyte receptor affinity was measured, and this characteristics was found to exceed that of the corresponding serum antibodies. to explain the heterogeneity of antibodies, two hypotheses have been proposed. one hypothesi ...	1981	6895274
[isolation and purification of the chloramphenicol-acetyltransferase from y. pestis ev cells with extrachromosomal resistance to the antibiotic by affinity chromatography].	purification of chloramphenicol acetyltransferase isolated from the cells of y. pestis ev-r with extrachromosomal resistance to chloramphenicol included ultrafiltration on the microporous membranes diaflo-xm 300 and biospecific chromatography on columns with cepharose 4b covalently bound with the reduced chloramphenicol. elution of chloramphenicol acetyltransferase was achieved by means of addition of native chloramphenicol to the buffer solution. such native chloramphenicol had higher affinity ...	1981	6938164
[immunostimulating properties of an extract isolated from aloe vahombe. 2. protection in mice by fraction f1 against infections by listeria monocytogenes, yersinia pestis, candida albicans and plasmodium berghei].	a partially purified extract of leaves of aloe vahombe, a plant endemic in the south of madagascar, administered intravenously to mice, protects them against infection of bacteria (listeria monocytogenes, yersinia pestis), parasites (plasmodium berghei) and fungus (candida albicans). the protective fraction must be administered two days before inoculation of the pathogenic agent. these results significantly confirm those we obtained in earlier study on mice infection by klebsiella pneumoniae. cu ...	1981	7044327
mutations to tolerance and resistance to pesticin and colicins in escherichia coli phi.	the universal colicin-indicator strain escherichia coli phi, unlike e. coli strain k-12, is sensitive to pesticin, a bacteriocin produced by wild-type yersinia pestis. eleven distinct phenotypes of e. coli phi mutants were obtained by selection for insensitivity to pesticin, group b colicins, the group a colicin s4, or coliphage t5. representative isolates from eight of these classes closely resembled resistant receptor mutants (cir-, fep-, and tona-) or tolerant mutants (tonb-, exbb-, exbc-, iv ...	1981	7012131
[persistence of l-forms of plague bacteria in experimental animals].		1981	7018126
[serologic affinity and specificity of action of pseudotuberculosis and coli-dysentery phages].	the study of serological properties, specificity and the range of action has revealed affinity between y. pseudotuberculosis phages (pst, 3m, kotlyarova, 2344, 2391), some coliphages (t2, t3, t4) and sh. dysenteriae phage (dd iv). the existence of serovar iii of y. pseudotuberculosis phages has been established; to this serovar phage pst belongs. newly isolated 2344 and 2391 belong to serovar i. the problem of the existence of y. pseudotuberculosis phages as an independent group is discussed.	1981	7023155
properties and pharmacological action of plague murine toxin.		1981	7025029
human plague -- texas, new mexico.		1981	6789063
[affinity of serum antibodies and splenocyte receptors in immunized cba mice].		1981	6171127
[gamma glutamyltransferase activity in the genus "yersinia" (author's transl)].	the expression of gamma-glutamyltransferase activity was studied among 87 strains representing all the yersinia species. y. pestis lacked constantly this enzyme, while y. pseudotuberculosis expressed it as a rule. this test, when positive, is useful for the exclusion of a suspected y. pestis diagnosis. all the other yersinia species, like most of the enterobacteriaceae, showed a gamma-glutamyltransferase activity.	1981	6112942
[response, to polymyxin, of plague microbe strains isolated from various natural foci and of their mutants with a decreased requirement in nutritional factors].	investigation of the response to polymyxin of 65 strains of pasteurella isolated from various foci and 46 their back mutants showed that all of them were usually highly resistant to polymyxin (mic 200--500 micrograms/ml). the pasteurella strains isolated in the gissaro-darvaz natural focus, turkey and congo were highly sensitive to polymyxin (mic 10--25 micrograms/ml). single cultures highly sensitive to the antibiotic were detected among the polymyxin-resistant strains. polymyxin-sensitive muta ...	1981	6271044
virulence-associated plasmids from yersinia enterocolitica and yersinia pestis.	a 44-megadalton plasmid associated with virulence and ca2+ dependence from yersinia enterocolitica 8081 was compared at the molecular level with a 47-megadalton plasmid associated with ca2+ dependence from yersinia pestis ev76. the plasmids were found to share 55% deoxyribonucleic acid sequence homology distributed over approximately 80% of the plasmid genomes. one region in which the plasmids differed was found to contain sequences concerned with essential plasmid functions. forty-five mutants ...	1981	6273385
how accessible are physicians? some findings and implications of the changing distribution of general practitioners in three new zealand cities.	an understanding of the changing distribution of general practitioners within urban areas is considered necessary as a first step towards understanding the problems of developing primary care services. both the distribution of general practitioners and the pattern of change 1966 to 1974 are analysed for three urban centres: auckland, wellington-hutt and christchurch. results indicate that newer suburbs are less well served than either established neighbourhoods or areas of high socio-economic st ...	1982	272508
[disorders in the position of teeth in patients with cleft palate].		1982	272279
[japanese literature on antibiotics. clxvi].		1982	351235
[3':5'-cyclonucleotidephosphodiesterase in yersinia pestis ev].		1982	6289056
[epidemiologic and hygiene significance of yersinia pestis and yersinia enterocolitica].		1982	6213893
rna synthesis in yersinia pestis during growth restriction in calcium-deficient medium.	yersinia pestis requires 2.5 mm ca(2+) for growth at 37 degrees c but not at 26 degrees c. after a shift from 26 to 37 degrees c in a ca(2+)-deficient medium, an ordered series of metabolic alterations occur which result in transition from a growing cell to a viable but non-proliferating cell. the earliest known alteration in normal metabolism associated with this transition is a termination of net rna synthesis. competitive rna/dna hybridizations with uniformly labeled rna and stable rna compet ...	1982	6174497
[determination of antibody affinity by using antigenic and antibody immunosorbents].	to determine the affinity of the active centers of antibodies, cellulose immunosorbents for antibodies and antigens have been used. the fixation of serum proteins on the sorbent, the interaction of fixed antibodies with a monovalent antigen and the graphic analysis of the results thus obtained allows one to assess not only the concentration of the effective active centers on the sorbent, but also all known characteristics of antibody affinity: the average association constant k0, the common asso ...	1982	6184912
[rapid method of determination of structural characteristics of lipopolysaccharide by the presence of aldoheptose in pasteurella pestis and pseudotuberculosis bacteria].		1982	6185755
[point of equivalence in the precipitation reaction and its use for determining antibody concentration and antigen valency].		1982	6186107
[reproducibility of the results of determining antibody and antigen activity in the takachi microtitrator].		1982	6181308
[rhamnose and melibiose cleavage by the causative agents of pseudotuberculosis].		1982	6181321
[monthly dynamics of the antitoxic immunity against diphtheria and tetanus and of normal antibodies to fraction i of the plague microbe in adults].	monthly characteristics of antitoxic immunity to diphtheria and tetanus toxoids in 3,334 adults in ryazan were determined. as a result, the following differences were established: the characteristics of antidiphtheria immunity were somewhat higher in the autumn-winter period and dropped to the minimal level in the winter-spring period; the maximal characteristics of antitetanus immunity clearly coincided with the hot season, its minimal characteristics with the cold season. for the first time th ...	1982	6211009
localization in yersinia pestis of peptides associated with virulence.	an avirulent guanine auxotroph of wild-type yersinia pestis was used to select isogenic mutants lacking invasive determinants of virulence including v and w antigens (vwa-), genetically linked fibrinolysin, coagulase, and pesticin activities (pst-), and the capacity to absorb exogenous pesticin and pigments including hemin (pgm-). after growth in environments known to favor expression of these factors by the parent, cells were converted to spheroplasts and disrupted to obtain preparations of cyt ...	1982	6210636
comparison of passive haemagglutination and enzyme-linked immunosorbent assay for serodiagnosis of plague.	sera of 42 suspect plague cases from ovamboland, namibia, were examined. elisa proved more sensitive than passive haemagglutination for the detection of f1 antibody and increased positive serodiagnoses of plague by 7-42%.	1982	6758973
plague: review of ecology.	yersinia pestis, the organism which causes plague in man and animals, circulates from host to host in nature by means of one of many flea vectors. there are about 340 mammals known to be susceptible to plague and over 30 fleas which are known to carry the organism. the habits of flea and host, usually a rodent, must to some extent coincide before infection can be established, and these habits are affected by the temperature and humidity of the environment, by vegetation cover, by season, indeed ...	1982	6765301
[trial use of polymyxin and erythromycin for isolating cultures of the plague microbe in the kyzyl-kum].	it is recommended that the hottinger agar medium with polymyxin or erythromycin be used for isolation of pure cultures of the plague microbe from specimens containing various species of microorganisms, except proteus. such a procedure was used in the kizil-kum for the bacteriological examinations with respect to plague. the procedure may be used in the natural foci with the strains resistant to these antibiotics.	1982	6295257
[experience in the comparative evaluation of the population sensitivity of mammals to the plague microbe based on the results of an epizootiological survey].	an essentially new method for the evaluation of the population susceptibility of mammals to pasteurella pestis without the experimental infection of the animals is proposed. this method consists in using the conjugate result of the mass bacteriological and serological survey of plague carriers (the ratio of the number of infected animals to that of the animals having had the disease). the susceptibility of 12 rodent and martes species has been studied with the use of this criterion on the basis ...	1982	6214127
[erythrocyte tanning and the characteristics of protein sensitins].		1982	7080743
[pesticinogenicity and pesticin sensitivity of pasteurella pestis strains isolated in the gornyi altai region].		1982	7090656
[the plague bacillus. i. kinetics of growth].		1982	7186794
[use of cyclophosphamide-immunodepressed mice in the diagnosis of plague].		1982	7186798
[effect of the cultivation temperature on the enzymes of sialic acid metabolism in the plague microbe].		1982	7154995
disc electrophoresis of phenol:acetic acid:water-soluble proteins for the identification of yersinia species.	disc electrophoresis of phenol:acetic acid:water extracts of yersinia pestis, y produced pseudotuberculosis, y enterocolitica, y philomiragia and y ruckeri protein separation patterns characteristic of each species. the patterns produced by y pestis, y pseudotuberculosis, y enterocolitica and y ruckeri showed features in common. those given by y philomiragia strains were quite distinctive and showed little similarity to the other yersinia species. all y enterocolitica strains produced similar pa ...	1982	7134648
[histopathology of yersinia pestis infection in rodents from plague foci in northeastern brazil].		1982	7144551
effect of exogenous nucleotides on ca2+ dependence and v antigen synthesis in yersinia pestis.	cells of yersinia pestis strain ev76 are known to cease growth after a shift from 26 to 37 degrees c in neutral ca2+-deficient medium; this effect is potentiated by mg2+. with 2.5 mm mg2+ and no added ca2+, restriction was relaxed at elevated ph at which maximum cell yields occurred in the presence of 20 mm exogenous atp. this atp-dependent growth was inhibited by ca2+ or 20 mm mg2+; the nucleotide was neither transported into the organism nor hydrolyzed extracellularly. with strain ev76, atp co ...	1982	7152680
[intestinal yersinia infection: pathogenesis, clinical course, epidemiology and diagnosis].	human abdominal yersiniosis is caused by yersinia enterocolitica and yersinia pseudotuberculosis. the organisms invade the intestinal wall and produce an inflammation of the gut and the mesenteric lymph nodes. their virulence appears to be determined by a group of plasmids of 40-48 megadaltons molecular size, which stimulate the production of v and w virulence antigens and mediate the capacity of y. enterocolitica to adhere to, and invade into, epithelial cells.	1982	6757111
temperature-modulated immunogenicity to yersinia pestis from yersinia enterocolitica o3.	the ability of yersinia enterocolitica o3, grown at 25 degrees c, to promote cross-immunity to y. pestis was lost after repeated subcultures at 37 degrees c, which selected for bacterial populations having lower in vivo survival. subculturing y. enterocolitica o3 from 37 to 25 degrees c restored the cross-immunogenicity although the in vivo survival remained low.	1982	7076305
experimental yersinia pestis infection in rodents after intragastric inoculation and ingestion of bacteria.	to clarify the pathogenesis of oral plague infection, we studied the susceptibility of three species of rodents to intragastric inoculation of yersinia pestis, described the pathology and progression of infection, and measured antibody responses to fraction ia antigen of y. pestis. the 50% lethal doses of bacteria by intragastric inoculation for mus musculus, zygodontomys pixuna, and rattus rattus were log10 = 6.32, 5.46, and 9.62, respectively, which were at least 1,000-fold higher than the val ...	1982	7095845
the first outbreak of human plague in lushoto district, north-east tanzania.	a one-week investigation was performed at mkunki and mavumo (ward of shume, lushoto district, tanzania) at the time of outbreak (june, 1980). rodents, people, domestic dogs and fleas were examined, 36 rats, mostly rattus rattus, were caught and used in serological and bacteriological analysis for plague. 48 fleas, mostly xenopsylla brasiliensis, were collected from the captured rodents. 413 people and 11 dogs were examined. all rodent, carnivorous and human sera were tested for plague antibodies ...	1982	7101402
[production of pesticins on synthetic nutrient media].	it was found that 96.2 per cent of the plague microbe cultures studied had a capacity to produce pesticin i on solid and liquid minimum synthetic nutrient media providing growth of the cultures. no pesticin iii was detected in the spheroplasts of plague microbes, when they were grown on the synthetic nutrient medium, while on the complete nutrient medium the inhibition zones were observed which was indicative of pesticin iii synthesis. the average value characterizing the titer of pesticin i pro ...	1982	7125618
solid-phase radioimmunoassay for detection of plague antigen in animal tissue.	a rapid and sensitive radioimmunoassay for the detection of soluble yersinia pestis fraction i antigen using antibody-coated beads and radiolabeled immunoglobulin was applied to spleen-liver extracts, rendered noninfectious by either treatment or filtration, from rodents dead of plague. the procedure was capable of detecting nanogram amounts of soluble plague antigen.	1982	7153344
evaluation of a qualitative isocitrate lyase assay for rapid presumptive identification of yersinia pestis cultures.	qualitative rapid tests for isocitrate lyase activity were positive for all of 1,695 yersinia pestis cultures tested but for none of 382 cultures of other gram-negative species. the test is simple, required only commonly available, easily prepared reagents, and provided clear-cut positive or negative results within 20 min.	1982	7050154
serologic survey for certain zoonotic diseases in black bears in california.	black bears (ursus americanus) from 3 geographic areas of california were tested for antibodies against agents of 6 zoonotic diseases: toxoplasmosis (indirect hemagglutination), q fever (microagglutination), trichinosis (latex particle agglutination), botulism (passive hemagglutination), leptospirosis (plate agglutination), and plague (enzyme-linked immunosorbent assay). of 149 sera tested, 40 (27%) were positive for toxoplasma gondii antibodies and 25 (17%) had antibodies against coxiella burne ...	1982	7174445
[experience using fraction i of the plague microbe for revaccinating experimental animals].	experiments on guinea pigs have shown that a pronounced revaccination effect develops in the animals receiving the booster injection of fraction i of pasteurella pestis 1.5--4 months after the primary immunization with live plague vaccine, while the booster injection of live plague vaccine produces a low revaccination effect due to the fact that this vaccine is badly adapted in the body after the primary immunization.	1982	7102182
advantages and use of laboratory-reared african multimammate mice (mastomys coucha) in the diagnosis of plague.		1982	7181544
[9 epidemic cases of bubonic plague in tananarive (madagascar)].		1982	7154899
[comparative evaluation of methods of obtaining phagolysates modelled on d'herelle's plague microbe phage].	various methods for phage multiplication have been tested: the method of cellophane membranes, the method of combined media, the method of forced aeration of a liquid medium, growth at suboptimal temperature and growth at optimal temperature under stationary conditions. the phage in a high concentration (n x 10(10) plaque-forming units per ml) can be obtained by any of these methods with the exception of the last one yielding lower (by 1 or 2 orders) effectiveness of multiplication. the main fac ...	1982	7158159
peripatetic plague.	cases of plague continue to occur in various parts of the world, including the western united states, where plague is endemic among the wild rodent population. in 1980, a case of plague acquired in new mexico and hospitalized in nebraska illustrated the problem of plague occurring in persons traveling from the state in which they become infected to another state. nine cases of plague in travelers were identified among the 166 cases of plague reported in the united states from 1950 to 1980. physi ...	1982	7053441
[isolation of l-form of yersinia pestis from wild rodents in an epizootic focus].	four y. pestis cultures with unbalanced growth and 15 y. pestis cultures in unstable l-forms were isolated from wild rodents rhombomys opimus in the vicinity of lake balkhash. morphologically they were mainly represented by granular, spheroplast-like and filiform elements. when stained with luminescent serum, they acquired specific fluorescence; in indirect hemagglutination they yielded positive result. electron microscopy revealed the presence of morphological elements characteristic of the pro ...	1982	7180264
surveillance of sylvatic plaque in oregon by serotesting carnivores.	in oregon, during 1974-1979, 10.3 per cent of 3.255 statewide blood samples from carnivores were positive for yersinia pestis. the per cent positive rate and geometric mean positive titer increase monthly from january (6.5 per cent) to june (21.7 per cent), and decline thereafter. data are presented on how geographic location, species, and time of year affect surveillance results. the correlation of carnivore plague surveillance with human cases in discussed.	1982	7125037
the role of the association in education for the profession.		1983	264831
photoinduced crosslinking of membrane proteins by fluorescein isothiocyanate.		1983	217376
left ventricular stiffness.	left ventricular stiffness is defined by the relationship between pressure and volume and can be altered by a variety of disorders. in disorders with high vlved, such as mitral regurgitation, protection of pulmonary capillaries from high pressure is provided by a pv shift. in contrast, increased stiffness is produced by ventricular hypertrophy or ischemic heart disease, which puts the patient at increased risk for pulmonary capillary hypertension. changing the ventricular pv relationship by ther ...	1983	348043
leads from the mmwr. plague--south carolina.		1983	6876307
chronic infections in laboratory rodents from inoculation of nonencapsulated plague bacilli (yersinia pestis).	infections with nonencapsulated y. pestis persisted for 9 weeks in mice and 56 weeks in rats after experimental inoculation. mice succumbed with bacteremia. rats developed chronic lesions containing nonencapsulated plague bacilli.	1983	6832323
serologic testing of badgers to monitor plague in southwestern idaho.	serologic testing of badgers (taxidea taxus) was used to monitor plague (yersinia pestis) in a townsend ground squirrel (spermophilus townsendi) population in 10,000 ha of the snake river birds of prey study area, idaho. eighty-six percent of the 294 sera tested in 1975 and in 1976 were positive. significantly fewer (72%) seropositives occurred in 1977. seasonal changes in the percentage of seropositives and the decline in 1977 were probably due to the phenology of the townsend ground squirrel a ...	1983	6842729
[effect of prolonged stay in the organism of the tick ornithodoros tartakovskyi (argasidae) on the properties of yersinia pestis].		1983	6844033
warning on a new potential for laboratory-acquired infections as a result of the new nomenclature for the plague bacillus.		1983	6668740
vwa+ phenotype of yersinia enterocolitica.	expression of the vwa+ phenotype of yersinia pestis in vitro is known to reflect maximum induction of virulence (or v and w antigens) at 37 degrees c with concomitant restriction of cell division. both phenomena are potentiated by 20 mm mg2+ and prevented by cultivation at 26 or 37 degrees c with 2.5 mm ca2+. we have now compared this classic plasmid-mediated phenotype with those of vwa+ yersinia pseudotuberculosis and yersinia enterocolitica which, unlike y. pestis, produce ancillary outer memb ...	1983	6832830
[discrete nature of the antibody affinity of immune sera and the importance of this factor for antigen binding].	after mixing an antibody immunosorbent with pasteurella pestis monovalent capsular antigen the concentration of the antigen in the free and bound states was evaluated. in this study the test points on the graph were found to be located on the lines characterizing different groups of antibodies differing in their affinity. the verification of the discrete structure of antibody affinity in 10 lots of hyperimmune horse serum showed the truth of this suggestion. the analysis of the role played by di ...	1983	6868893
[restoration of natural plague foci resulting from endemics of the causative agent of the disease in various animals].		1983	6888331
[effect of the repeated infecting feeding with plague microbe on block formation in fleas (siphonaptera)].		1983	6844034
[precipitation of the antigens of the causative agents of plague, glanders and melioidosis using aqueous saline extracts of various plant species].	the interaction of the aqueous saline extracts of 55 plant species with the antigens of the causative agents of plague, glanders and melioidosis in the reaction of immunodiffusion (rid) in gel has been studied. the aqueous saline extracts obtained from the seeds of 12 plant species have been revealed to possess precipitating capacity. at the same time these extract have been found to ensure, as a rule, rid with several antigens under test.	1983	6419513
[antigenic activity of external membrane proteins in yersinia pestis ev].	the study of immunocomplexes obtained from antisera to the preparations of y. pestis outer membranes and membrane proteins has revealed that outer membrane proteins are involved in the formation of the immunocomplex and belong to previously unknown y. pestis ev antigens.	1983	6405562
use of uv-irradiated bacteriophage t6 to kill extracellular bacteria in tissue culture infectivity assays.	we have utilized 'lysis from without' mediated by uv-inactivated bacteriophage t6 to eliminate extracellular bacteria in experiments measuring the internalization, intracellular survival and replication of yersinia pestis within mouse peritoneal macrophages and of shigella flexneri within a human intestinal epithelial cell line. the technique we describe has the following characteristics: (a) bacterial killing is complete within 15 min at 37 degrees c, with a greater than 10(3)-fold reduction in ...	1983	6338113
diagnosis complicated by group a streptococcus.		1983	6367461
plague in south african rodents 1972-1981.	sera from 3012 rodents of 24 species captured in south africa during the period 1972-81 were tested for antibody to the fraction 1 antigen of yersinia pestis by passive haemagglutination. antibodies were found in seven (0.23%) rodents of three species. these were desmodillus auricularis and tatera brantsii in the northern cape province and rhabdomys pumilio in the eastern cape province. rodents were found positive in 1972, 1974, 1975 and 1979, indicating that plague continues to circulate in rod ...	1983	6868103
studies on plague in the eastern cape province of south africa.	investigations were carried out in the area of a human plague outbreak in march 1982 at coega in the eastern cape province of south africa. trapping revealed that rodent populations were high owing primarily to a population increase of the four-striped mouse, rhabdomys pumilio. flea populations were low and had been declining in the eastern cape province since october 1981. the results of a serological survey from march to october 1982 showed haemagglutinating antibody to yersinia pestis in 0.35 ...	1983	6665833
[localization of antigen f-1 of yersinia pestis ev by an immunoferritin method].	the localization of antigen f-1 in y. pestis strain ev, line (formula; see text) has been studied by means of specific monoreceptor ferritin-labeled antibodies. the study has given direct proofs that antigen f-1 is localized on the surface of the cell wall and in bacterial microcapsules. the substance of the microcapsule is loosely bound with the cell body and easily diffuses into the intercellular space, the antigenic properties of the substance remaining unchanged.	1983	6624313
[dna-methyltransferase of the plague microbe].	dna-methyltransferases of yersinia pestis ev, plague agent bacteria were isolated by p-ii phosphocellulose chromatography. the methylating activity is eluated by two fractions at the 0.47 m and 0.53 m nacl concentrations. methylases of the plague microbe are specific with respect to two bases (adenine and cytosine) and are capable of modifying both native and denaturated form of dna.	1983	6636308
isolation and identification of ropy bacteria in raw milk.	approximately 4.2% of 4,000 maryland-virginia raw milk tanker samples developed ropiness when incubated at 10 degrees c. of the 56 bacterial isolates 30 were identified by species. klebsiella oxytoca and pseudomonas aeruginosa were isolated most frequently. other ropy isolates were identified as pseudomonas spp., chromobacterium, flavobacterium multivorum, presumptive yersinia pestis, enterobacter agglomerans, klebsiella pneumoniae, and pasteurella-actinobacter spp. six of the klebsiella oxytoca ...	1983	6685140
serologic survey of california wild hogs for antibodies against selected zoonotic disease agents.	blood samples were collected from trapped or hunter-killed wild hogs (sus scrofa) in 4 areas of california. sera were tested for antibodies against 7 zoonotic disease agents. antibodies against brucella sp were detected in 21 (15%) of 136 samples. antibodies against coxiella burnetii were found in 50% of the collected samples (67 of 135 tested). of the 135 wild hogs screened for pseudorabies virus, 4 (3%) were seropositive. leptospira interrogans antibodies were discovered in 118 (87%) of the 13 ...	1983	6315659
ecology of plague in africa: response of indigenous wild rodents to experimental plague infection.	the mastomys natalensis species complex, subdivided into genetically distinct species having diploid chromosome numbers 2n = 32 and 2n = 36, is a reservoir for several zoonoses including lassa fever and plague. this report describes a study to determine whether these sibling species and three other rodent species have different potential as reservoirs for plague. it was found that m. natalensis (2n = 32) was significantly more resistant to experimental plague infection (50% survived inoculation ...	1983	6345015
repression of the virulence of yersinia pestis by an f' plasmid.	an f-lac plasmid from escherichia coli was transferred to virulent yersinia pestis, resulting in the repression of virulence. the y. pestis f-lac clones retained all of the known virulence traits but were avirulent and calcium independent. every lac segregant derived from the f-lac clones was fully virulent and calcium dependent.	1983	6832826
the vwa+ virulence factor of yersiniae: the molecular basis of the attendant nutritional requirement for ca++.	the plague v antigen is a cytoplasmic 90,000-dalton peptide, and the w antigen is a primarily extracellular 145,000-dalton lipoprotein of unknown origin. wild-type yersiniae undergo restriction of cell division when producing these plasmid-mediated virulence antigens (vwa+) during cultivation at 37 c in ca++-deficient media. in yersinia pestis both restriction and synthesis of v and w antigens are potentiated in this environment by elevated mg++ and prevented by ca++ or exogenous nucleoside trip ...	1983	6195719
[attempt at the experimental infection of isabelline wheatears (oenanthe isabellina temm., 1829) with the causative agent of plague].		1983	6225008
[construction of a suspension diagnosticum to test for yersinia pestis endotoxin and homologous antibodies].		1983	6195409
[methods of preparing and purifying the capsular antigen and endotoxin of the causative agent of plague].		1983	6201660
warning on a new potential for laboratory-acquired infections as a result of the new nomenclature for the plague bacillus.	the new name for the plague bacillus (formerly "yersinia pestis") is y. pseudotuberculosis subsp. pestis, while the pseudotuberculosis bacillus is named y. pseudotuberculosis subsp. pseudotuberculosis. any tendency to abbreviate these names on labels of cultures, especially by omitting the subspecies epithet, must be avoided because of the risk of confusion between the dangerous plague organism and the pseudotuberculosis bacillus.	1983	6603926
entomological, bacteriological and serological observations after the 1977 plague outbreak in mbulu district, tanzania.		1983	6617551
[concentration and purification of d'erell's phage].		1983	6086049