Publications

natural plant enzyme inhibitors: part vii--alpha amylase inhibitors & amylases in plant tubers.		1979	94300
[method of preparing the tularemia antigen for an erythrocyte diagnosticum].		1979	85742
endotoxin shock in the beagle dog.		1979	94472
the human ia system.		1979	94505
properties and usefulness of the original k-562 human myelogenous leukemia cell line.		1979	95026
possible role of the friend virus life cycle in differentiating friend leukemia cells treated with interferon.		1979	94575
prostaglandin synthesis inhibition and monoamine metabolites in the rat brain.	the effect of indomethacin 3 mg/kg on levels of homovanillic acid (hva), 4-hydroxy-3-methoxy phenyl ethylene glycol (hmpg) and 5-hydroxy indol acetic acid (5hiaa) was studied in rat striatum and olfactory tubercle with and without pretreatment with morphine 10 mg/kg. indomethacin caused a small decrease in resting levels of hva in striatum but not in olfactory tubercle. no effects were seen on resting or morphine induced changes in the levels of these monoamine metabolites. likewise indomethacin ...	1979	94946
comparison of antigenic properties among various strains of treponema hyodysenteriae.	agglutinin-absorption and precipitin-absorption studies demonstrated that three strains of treponema hyodysenteriae isolated from cases of swine dysentery were antigenically different from each other and also from a spirochete isolated from a clinically normal dog. each of the strains of t. hyodysenteriae also possessed two common antigens.	1979	95077
[determination of the internal association constant as a measure of the affinity of erythocyte-fixed antibodies that interact with mono- and multivalent antigens].	the fraction of antibody-bound determinants of a polyvalent antigen is determined by the fraction of free antigen molecules and the valence of the antigen. the internal association constant for antibodies fixed onto erythrocytes can be found by the suspension method, the index obtained in this process being similar when both monovalent and polyvalent antigens are used. the sensitivity of the antibody-erythrocyte diagnostic preparation in the passive hemagglutinin test depends on the affinity of ...	1979	92866
[phenomenon of parental resistance and its genetic regulation].	lymphocytes of mice f1 (cba x m523) and f1 (a x m523) transplanted to 1000 r irradiated cba or a mice responded to the test antigens--srbc or s. typhi vi-antigen--by formation of 100--1000 times less antibody forming cells than in syngeneic recipients. an intermediate result is achieved when the lymphoid cells are transplanted to the irradiated m523 mice. lymphocytes of mice f1 (a x cba), f1 (cba x c57bl/6), or f1 (a x a.ca) developed a similar immune response in the irradiated syngeneic mice an ...	1979	34452
[determination of the concentration of active centers and the antibody heterogeneity index by using the precipitation in fluid reaction].	equivalence zone in the precipitation test was characterized by the fact that the number of the antigen determinants was equal to the number of active antibodies centres, irrespective of the heterogeneity of the latter. this permits to assess the antibody concentration in the values of the antigen valency. the new method of determination of the antibody heterogeneity index is based on recording the titre of the antigen and antibodies in the equivalence zone.	1979	84456
[antitumor activity and preclinical pharmacologic evaluation of pingyangmycin (author's transl)].		1979	95444
separation of t and b lymphocytes from various mouse strains by density gradient electrophoresis.	t and b mouse spleen lymphocytes were separated by density gradient electrophoresis on the basis of their surface charge. in all strains examined, the t lymphocytes were found in the high mobility fractions and the b in the low. the t and b cells were separated completely in most fractions, with some overlapping in the middle. significant differences were found in the electrophoretic distribution profiles between the strains: c57bl/6j, c57bl/10j, (balb/cxc57bl/6j)f1, and all the following: b6.c- ...	1979	95175
effects of ovarian hormones on cell membranes in the rat uterus. i. freeze fracture studies of the apical membrane of the liminal epithelium.	freeze fracture techniques have been used to study the apical membrane of cells of the luminal epithelium of the rat uterus under various hormonal regimes. in the ovariectomized but otherwise untreated rat, intramembranous particles (imps) occur at a density of 1395 +/- 122 per micron 2; they appeared spherical and uniformly distributed. after 3 days treatment with estrogen, no change in appearance or density was found, but 3 days of progesterone treatment produced a significant increase in imp ...	1979	95176
immunodiffusion study on group-specific antigen of mc-29 chicken hepatoma.	rabbit serum against crude mc-29 hepatoma extract does not contain anti-avian gs antibodies detectable by gel diffusion methods. rabbit serum containing antibodies against purified gs 1, gs 2, gs 3 and gs 4 antigens of avian myeloblastosis virus reveals gs 1 antigen in mc-29 hepatoma extract.	1979	95333
k562 human leukaemic cells synthesise embryonic haemoglobin in response to haemin.		1979	95354
antigenic similarity between squamous cell carcinoma of horn (horn cancer) and normal bovine foetal tissues.	normal bovine foetal (liver and skin) and horn cancer tissue antigens were examined using double diffusion agar gel precipitation and immuno-electrophoretic tests to detect any cross reactivity among them. rabbit horn cancer antisera absorbed with normal bovine liver, skin and horn core epithelium antigens, when tested with foetal skin and liver (4 to 6 months of gestation), revealed the presence of 2 foetal antigens in horn cancer. immuno-chemically 2 of the horn cancer antigens were found to b ...	1979	95358
hearing thresholds with outer and inner hair cell loss.	hearing impairment and related cochlear histopathologic changes were evaluated in experimental animals after treatment with aminoglycoside antibiotics or exposure to intense sound. in the course of treatment with kanamycin, neomycin, or dihydrostreptomycin, permanent hearing loss in monkeys and guinea pigs occurred first at the high frequencies and progressed toward the lows. exposure to different octave bands of noise at 120 db spl in monkeys and chinchillas produced permanent hearing loss at f ...	1979	95382
immunological relationships among transaldolases in the genus bifidobacterium.	antisera were prepared against electrophoretically homogeneous transaldolase (dihydroxyacetone transferase, e.c. 2.2.1.2.) of bifidobacterium thermophilum (b. ruminale) ru326 (atcc25866), b. cuniculi ra93 (atcc27916) and b. 'minimum' (homology group) f392 (atcc 27538). crude extracts of eighty six strains previously assigned to twenty one species of the genus bifidobacterium on the basis of deoxyribonouclelic acid (dna) homology (dna-dna hybridization), were compared by double diffusion tests on ...	1979	95384
a case of a needle stick.		1979	95411
[replacement solutions and hemodilution].	by definition, haemodilution involves the use of filling solutions, but in this technique the role of different solutions has yet to be clearly defined. amongst the criteria of choice used at the present time, two would seem to be essential: good tolerance, limiting the risks of complication and side effects to an absolute minimum; and a sufficiently long intravascular half-life ensuring good control of blood volume. on this basis, amongst the crystalloids ringer lactate offers definite advantag ...	1979	95461
[biosynthesis of penicillin upon periodic culturing of penicillium chrysogenum with an exponentially increasing glucose supply].	penicillium chrysogenum was cultivated under controlled conditions and at constant specific growth rates regulated by glucose supply. the rate of penicillin synthesis (units/mg dry weight.hr) and pattern of time changes of the synthesizing capacity of the culture depended on the specific growth rate (hr-1). the arrest of penicillin synthesis was induced by the inherent changes of the culture rather than by external factors, e.g. use of substrates, changed limitation, accumulation of inhibitory m ...	1979	95828
fat-induced jejunal inhibition of gastric acid secretion and release of pancreatic glucagon, enteroglucagon, gastric inhibitory polypeptide, and vasoactive intestinal polypeptide in man.	the effect of intrajejunal (i.j.) infusion of fat on meal-stimulated gastric acid secretion and release of pancreatic glucagon (pg), enteroglucagon (eg), gastric inhibitory polypeptide (gip), and vasoactive intestinal polypeptide (vip) was studied in seven healthy volunteers. i.j. fat markedly inhibited meal-stimulated acid secretion as compared to a control study with i.j. saline infusion. the acid inhibition was accompanied by augmental plasma concentrations of eg, gip, and vip but not of pg, ...	1979	107575
evidence of a high-activity c type of carbonic anhydrase in human ciliary processes.	carbonic anhydrase activity was found in the ciliary process of fresh human donor eyes, originating from an enzyme antigenically similar to the erythrocyte high-activity isoenzyme hca c. it was sensitive to inhibition by acetazolamide and resistant to inhibition by halides like hca c. the enzyme is probably identical with hca c. its tissue concentration was one fifth to one tenth of that in the human kidney. the erythrocyte low-activity isoenzyme hca b was also found in the processes as a contam ...	1979	110722
frequency and fate of human renal allografts contaminated prior to transplantation.	bacterial cultures were done from donor ureter and/or graft perfusion fluid on 92 of 112 patients who had renal transplantations during 1977. three samples of perfusion fluid and 14 samples of donor ureter contained bacteria. in nine cases there was a gram-positive organism, and in 10 cases a gram-negative rod was (among) the contaminant(s). there was no difference in the rate of graft survival, patient survival, or in the frequency of major postoperative complications between the two groups. on ...	1979	107605
spinal cord evaluation by cortical evoked responses.	in ten monkeys, selective segmental lesions of the dorsal columns at the upper thoracic and middle cervical levels resulted in almost total attenuation of the cortical evoked potential responses to peripheral nerve stimulation. conversely isolated segmental dorsal column preservation showed intact transmission of the evoked responses at rostral spinal cord, nucleus ventralis posterior lateralis, and cortical levels. responses recorded from the intralaminar thalamic nuclei in the region of nucleu ...	1979	107931
acetylated methylmannose polysaccharide of streptomyces griseus. locations of the acetyl groups.	the positions of esterification of the 4 to 5 acetyl residues in the acetylated methylmannose-containing polysaccharide from streptomyces griseus have been established by the methyl replacement technique, wherein ester substituents are specifically replaced with methyl ether substituents. the newly incorporated methyl groups were distinguished from 3-o-methyl groups by the use of polysaccharide containing radioactively labeled endogenous methyl groups. the positions of methyl group localization ...	1979	107171
effects of dietary composition on somatomedin activity in growing rats.		1979	107298
inhibition of neisseria gonorrhoeae by normal human saliva.	saliva was found to be a powerful and specific inhibitor of neisseria gonorrhoeae. although 28 other species of bacteria were tested, including neisseria meningitidis, neisseria pharyngis var flava, neisseria lactamica, and neisseria catarrhalis, we failed to find any others sensitive to saliva under similar conditions. the physical properties of the inhibitory substance indicated that it might be salivary alpha-amylase. to test this hypothesis alpha-amylase was extracted from saliva and was sho ...	1979	106919
production, purification, and properties of dextransucrase from leuconostoc mesenteroides nrrl b-512f.	the production of dextransucrase from leuconostoc mesenteroides nrrl b-512f was stimulated 2-fold by the addition of 0.005% of calcium chloride to the medium; levansucrase levels were unaffected. dextransucrase was purified by concentration and dialysis of the culture supernatant with a bio-fiber 80 miniplant, and by treatment with dextranase followed by chromatography on bio-gel a-fm. a 240-fold purification, with a specific activity of 53 u/mg, was obtained. contaminating enzyme activities of ...	1979	106966
liver transplantation.		1979	107000
reduced uptake of oestrone and corticosterone by cells from cirrhotic rat liver.		1979	107697
dietary modification of amphetamine stereotyped behaviour: the action of tryptophan, methionine, and lysine.	rats fed diets high in tryptophan, methionine, and tryptophan plus methionine or lysine were subsequently injected with 10 mg/kg d-amphetamine. the amount of amphetamine-induced stereotyped behaviour observed varied as a function of the dietary addition, with methionine showing the greatest difference to controls, and lysine the least. whole brain catecholamine levels and 5-hydroxytryptamine levels also showed amino acid-specific changes.	1979	108724
[survival capacity of certain pathogens under environmental conditions].		1979	103703
a receptor for polymerized human and chimpanzee albumins on hepatitis b virus particles co-occurring with hbeag.	a receptor for polymerized human serum albumin was demonstrated on dane particles as well as on 20-nm hepatitis b surface antigen particles, isolated from asymptomatic carriers of hepatitis b virus who were positive for hbeag. in contrast, such receptor was not born by 20-nm hepatitis b surface antigen particles obtained from carriers positive for antibody to hbeag. hepatitis b surface antigen particles with the receptor were heavier than those without, and when treated with pronase, they became ...	1979	103774
autoimmune interaction measured in a postlabelling microcytostasis assay.	a postlabelling microcytostasis assay was developed to assess primary immune interaction between normal rat lymphocytes and autologous testis cells. in this vitro model of experimental autoimmune orchitis (eao) unprimed t cells respond to a sertoli-like subpopulation of testis cells during a 4 day culture period. the t effector cells exert a cytostatic effect on the monolayer-forming target cells. the number of remaining target cells, which inversely correlates with the intensity of the autoimmu ...	1979	154536
mg2+-dependent adenosine triphosphatase in isolated synaptic vesicles. attribution of most of the enzymic activity to an actomyosin-like protein.		1979	154515
[proline-dependent wild strains and proline-dependent mutants of the plague microbe].	it is found that the growth of yersinia pestis wild strains, isolated from citellus musicus menetrié in the central caucasus, depends on the presence of proline in the medium. proline can not be substituted by glutamic acid, other amino acids or vitamins. 28 proline-requiring mutants were selected from y. pestis marmot strain 20b. three groups of proline-requiring y. pestis mutants are established, similar to those of escherichia coli. the requirement of proline does not affect the virulency, pi ...	1979	159850
secretory granules of the duodenal enterochromaffin cells of the cat.		1979	222959
[blood transfusion and viral diseases. recent acquisitions concerning viral hepatitis viruses, cytomegaloviruses and epstein-barr virus].	in recent years, an increasingly clear picture has been formed of the virus-induced syndromes that may follow a blood transfusion or the use of blood derivatives. up to about 10 years ago, post-infusion infection was predominantly due to serum hepatitis. blumberg's discovery of hbsag (formerly known as australia antigen) has made it possible to check and prevent viral hepatitis, type b, and to recognise such distinct forms as the mononucleosis-like syndrome caused by cytomegalic virus, infectiou ...	1979	219399
transcription of the marek's disease virus genome in a nonproductive chicken lymphoblastoid cell line.		1979	219594
troponoids. 3. synthesis and antiallergy activity of n-troponyloxamic acid esters.	a number of oxamic acid derivatives of tropones and tropolones were synthesized and their antianaphylactic activity was determined in passive paw anaphylaxis (ppa). several of these esters possessed oral activity. a comparison of the effect on the biological activity of the esters and the corresponding acid and its salt is reported. the experiments suggesting a relationship between the activity and the bioavailability of the ester 19 are also described. a study of the fate of ester 19 in serum o ...	1979	229222
lethal effect of protamine and histone on competent bacillus subtilis cells. inhibition of genetic transformation by protamine in sublethal concentration.	under experimental conditions of genetic transformation, protamine and total histone were bactericidal for bacillus subtilis cells. the abilities to cause lethality were very similar for both, either protamine or histone, with no antagonistic effects amongst these natural polycations. with both basic proteins acting simultaneously the enhancement was higher than a summation of the separate lethal effects. sublethal concentration of protamine added at the beginning of transformation time, produce ...	1979	111002
inhibition of tritiated thymidine incorporation in cultured cells by rat kidney extract.	kcl extract from rat kidney, rat liver, and morris hepatomas inhibited [3h]thymidine incorporation into cultured cells. tissues came from male inbred buf rats. the most pronounced inhibition was achieved with the kidney extract. protein synthesis was not inhibited during a 24-hour exposure of the cells to the inhibitor. incorporation of [3h]deoxycytidine was inhibited, as was cell growth, when the kidney kcl extract was present for several days. [3h]thymidine incorporation was inhibited almost i ...	1979	155753
early changes in the arterial endothelium under various pathological conditions: an electron histochemical study with visualization of altered permeability using electron microscopic tracers.	the authors have studied the endothelial changes in the aorta and the arteries of heart, kidney and other organs in cholesterol fed rabbits and endotoxin administrated rats through electron histochemical and vascular clearance methods. the vascular changes are variable presumably due to the functional and morphological difference of vessels. the administration of cholesterol and endotoxin may result in increased vascular permeability which is directly related to the qualitative increase and decr ...	1979	155387
circular dichroism and ultraviolet absorbance of calf thymus dna in presence of ch3hgoh.		1979	156470
[experimental protective of fraction i of the plague microbe].	the immunogenic properties of the freeze-dried preparation of fraction i tisolated from the culture of avirulent pasteurella pestis strain were studied in experiments on hamadryas baboons, guinea-pigs and white mice. the preparation was found to have a pronounced protective effect in hamadryas baboons and white mice, especially when the preparation was used in mixture with incomplete freund adjuvant. in hamadryas baboons resistance to infection was shown to correlate with hemagglutionation antib ...	1979	116458
[examinations on the behaviour of grampositive and gramnegative bacteria in aqua bidest and tap-water at different initial colony counts and different temperatures (author's transl)].	experiments were done about the behaviour of 5 different strains of staph. aureus, strept. faecalis, e. coli, ser. marcescens and p. aeruginosa in aqua bidest and sterile tap water at 20 degrees c, 30 degrees c and 40 degrees c. the behaviour of 3 different initial colony counts in each case was examined. colony forming units (cfu) were evaluated at the beginning and after 1, 2, 4, 6 and 24 h. cfu were reduced at staph. aureus and e. coli in aqua bidest and tap water not earlier than after 4 h, ...	1979	120654
[in vitro biosynthesis of beta-lipotropin in brain tissue].	we have recently developed methods to identify biosynthetized beta-endorphin and beta-lipotropin (beta-lph) following incubation of rat pars intermedia with radioactive amino acids. we used the same approach for rat brain tissue. in the striatum we found a peptide similar to beta-lph while its identification in hypothalamus was less positive. this is the first demonstration of such biosynthesis and it could well be an important step in determining the biosynthetic patterns of cerebral endorphins ...	1979	108023
[melanin-producing strains of pseudomonas aeruginosa].		1979	111005
the viability of cryopreserved aegyptianella pullorum carpano, 1928 in the vector argas (persicargas) walkerae kaiser and hoogstraal, 1969.		1979	107668
adverse hemodynamic and ultrastructural changes in dog hearts subjected to protein-calorie malnutrition.	in the absence of thiamine deficiency, the specific effects of protein-calorie malnutrition on left ventricular (l.v.) function are unknown. mature beagle dogs of both sexes were subjected to a hypocaloric, nitrogen-poor diet which resulted in a weight loss of approximately 40% after seven weeks. following preparation of this nutritional model, myocardial contractility was assessed acutely by obtaining isovolumetric l.v. contractions on cardiopulmonary bypass at constant heart rate, mean aortic ...	1979	107775
fascioloides magna: development in selected nonruminant mammalian hosts.		1979	108129
accumulation of iron by yersiniae.	escherichia coli, bacillus megaterium, and three species of yersiniae grew rapidly without significant production of soluble siderophores in a defined iron-sufficient medium (20 microm fe3+). in iron-deficient medium (0.1 to 0.3 microm fe3+) all organisms showed reduced growth, and there was extensive production of siderophores by e. coli and b. megaterium. release of soluble siderophores by yersinia pestis, y. pseudotuberculosis, or y. enterocolitica in this medium was not detected. citrate (1 ...	1979	108243
isolation and characterization of bacterial flagellar hook proteins from salmonellae and escherichia coli.	flagellar hook proteins from salmonella and escherichia coli were dissociated in acid and purified by diethylamino-ethyl-cellulose column chromatography. these two proteins had the same electrophoretic mobility in sodium dodecyl sulfate-polyacrylamide gels. however, analytical electrofocusing patterns showed that these proteins had different isoelectric points (4.7 for salmonella typhimurium and 4.4 for e. coli). immunodiffusion and immuno-electron microscopy carried out with antisera prepared a ...	1979	108251
evaluation of high-protein supplements in children with protein energy malnutrition.	the present study was designed to test the comparative efficacy of cow's milk, a protein, vitamin and mineral mixture (pvm) and soybean textured vegetable protein (somos) as supplements to maize meal porridge in the dietary treatment of children with protein energy malnutrition (pem). each diet was designed to provide approximately 480 kj/kg with 2 protein/kg from the test protein, and 1,8 g protein/kg from maize. response to treatment was measured by loss of oedema, subsequent weight gain, rate ...	1979	111358
tuberculosis of the mandible presenting as 'lumpy jaw'.		1979	108413
identification of 15-keto-9, 11-peroxidoprosta-5, 13- dienoic acid as a hematin-catalyzed decomposition product of 15-hydroperoxy-9, 11-peroxidoprosta-5, 13-dienoic acid.	a labile prostaglandin was isolated as one of the products generated from [1-14c] eicosatetraenoic acid incubated with sheep vesicular gland microsomes. the eicosatetraenoic acid metabolite amounted to ca. 16% of the total radiolabeled products. formation of this new prostaglandin was prevented when heat-denatured microsomes were employed or when incubation mixtures were supplemented with indomethacin or phenol. however, incubation of prostaglandin g2 (pgg2) with hematin in the presence or absen ...	1979	108495
pantothenase.		1979	108511
cerebellar cortical atrophy in an adult japanese macaque.		1979	111404
neutralizing influenza antibodies, iga and total protein in the nasopharyngeal secretions of subjects vaccinated by nasal route with the inactivated influenza vaccine prepared in the "stefan s. nicolau" institute of virology.	intranasal administration of two doses of the inactivated influenza vaccine prepared in the "stefan s. nicolau" institute of virology was followed by rises in the level of neutralizing secretory influenza antibodies in 82% of the cases. the concomitant study of secretory antibody, iga and total protein levels, as well as of the serum hai influenza antibodies demonstrated that their evolution was parallel only in 23% of the vaccinees. the percentage of secretory antibody conversion was similar to ...	1979	111408
[bactericidal effect of disinfectants on various strains of mycobacterium tuberculosis].		1979	113848
pharmacological modification of experimental tardive dyskinesia.	cebus apella monkeys subjected to chronic haloperidol administration develop neurologic disturbances very similar to neuroleptic-induced acute dystonia human beings. after varying lengths of time, certain monkeys develop a prolonged dyskinetic syndrome resembling tardive dyskinesia (td), as seen clinically. two monkeys with signs of td were given single intramuscular injections of various compounds with known effects on the catecholaminergic, cholinergic, serotoninergic and gaba-ergic neurotrans ...	1979	115227
pancreatic transplantation in cases of diabetes complicated by renal insufficiency.		1979	115240
the primer trna for moloney murine leukemia virus dna synthesis. nucleotide sequence and aminoacylation of trnapro.	the nucleotide sequence of a trna primer molecule for initiation of moloney murine leukemia virus dna synthesis has been determined. the sequence is heterogeneous in two positions but both forms, when drawn in a cloverleaf structure, have anticodon specificities for proline. we have termed these isoacceptors trna1pro and trna2pro. aminoacylation studies confirmed the specificity for proline. the two forms occur in approximately equal amounts in uninfected mouse and chicken cells and in moloney l ...	1979	115865
sensitization of myelinated nociceptive afferents that innervate monkey hand.		1979	115969
spontaneous zinc deficiency in marmosets, saguinus mystax.	moustached marmosets, saguinus mystax, developed alopecia, skin lesions and general debilitation approximately 6 months after being brought into our laboratory. these lesions resembled the signs of zinc deficiency in pigs, rats and squirrel monkeys. the marmosets were fed a commercial monkey diet containing 150 parts per million zinc and about 100 g of apples and oranges per week. the addition of 40 parts per million zinc to the drinking water brought about improvement in hair coat and skin cond ...	1979	117220
[immunochemical study of heterogenous antigens y. pestis ev similar to human red cells].	franctions containing heterogenous antigens y. pestis ev similar to human red cells can be obtained by the method of immunosorption of antigens by fixed antibodies on polyacrylamide gel.	1979	117851
[oculomotor reflex evoked by vibrassae stimulation in the cat].	the oculomotor effects of vibrissae stimulation have been studied in the "encéphale isolé" non-anaesthetized cat. intracellular recording of lateral rectus motoneurones showed an excitatory projection via the ipsilateral infraorbital nerve to these motoneurones. the afferent fibers are type a alpha, recuited with a low threshold (0.2-0.5 ma) and convey information about vibrissae displacement.	1979	120789
experimental gingivitis in odu plaque-susceptible rats. iii. toxic activity of the rat dental plaque.	the toxicity tests of the dental plaque from odu plaque-susceptible rats showed strong lethal effect on mice, and abscess forming effect on guinea-pigs. bacterial cells isolated from the rat dental plaque also showed strong toxicity on both animals and capillary permeable activity on rabbits. among these bacterial cells, corynebacterium showed the strongest toxic effects on these animals. these facts suggested an important role of the dental plaque on initiation and development of gingivitis and ...	1979	289757
measuring the efficacy of vaccination in affording protection against plague.	the relationship of f1 antibody titre to protection against plague was investigated by subjecting seropositive laboratory rats to virulent challenge and observing for survival. the passive haemagglutination (pha) test in microtitre was employed for serology. rats vaccinated with live vaccine ev76 (51f), killed u.s.p. vaccine, or f1 antigen and challenged by subcutaneous inoculation of 1 x 10(3) to 5 x 10(5)yersinia pestis survived at similar rates that, overall, equalled 6% at titres less than 1 ...	1979	312163
susceptibility to cefazedone and cefazolin and production of beta-lactamase in in bacteroides fragilis and other species of bacteroidaceae.		1979	314805
veneral diseases.		1979	313576
analysis of t cell subpopulations by laser doppler spectroscopy and the association of electrophoretic mobility differences with differences in rosette-forming affinity.		1979	313961
third international symposium on transfer factor.		1979	314845
ultrastructural and biochemical changes in newborn rabbit liver after transplacental effect of phenobarbital.		1979	315341
the requirement of ia-positive accessory cells for the induction of hapten-reactive cytotoxic t lymphocytes in vitro.		1979	315427
[prevention and therapy of viral hepatitis].		1979	253774
[experimental infection of biomphalaria glabrata with schistosoma mansoni in the presence of helisoma duryi].		1979	262314
[efficacy of various culture media in the preservation of yersinia pestis strains].		1979	262317
[brain aging. ultrastructural study of changes in man and laboratory animals].	the authors present a study on ultrastructural changes observed in aged human and animal brain. these changes are analyzed and compared with those described in classic optic microscopy and with those observed in experimental models of the same lesions.	1979	262351
[sensitivity of different strains of the causative agent of plague to disinfectants].	various strains of the plague microbe was found to have statistically significant differences in their sensitivity to phenol, formaldehyde and chloramine. these differences did not correlate with the origin, virulence and nutritional requirements of the plague strains. the sensitivity of the plague microbe to formaldehyde and phenol was found to be related to the permeability of its cell wall.	1979	463428
epidemiologic survey of sylvatic plague by serotesting coyote sentinels with enzyme immunoassay.	the geographic distribution and areas of high sylvatic plague activity in california were verified by using coyotes (canis latrans) as sentinel animals. antibody levels against yersinia pestis were tested using the enzyme-labelled antibody (ela) test and the microtiter passive hemagglutination and hemagglutination inhibition. a survey using the ela test indicated that the overall antibody prevalence among 143 coyotes was 21%. by geographic regions, the highest antibody prevalence was 27% among c ...	1979	382839
site-specific recombination leading to the integration of phages p1 and p7.		1979	385221
synthesis and properties of fluorescent nucleotide substrates for dna-dependent rna polymerases.	a new class of fluorescent nucleotide analogs which contain the fluorophore 1-aminonaphthalene-5-sulfonate attached via a gamma-phosphoamidate bond has been synthesized. both the purine and pyrimidine analogs have fluorescence emission maxima at 460 nm. cleavage of the alpha-beta-phosphoryl bond produces change in both the absorption and fluorescence emission spectra. the fluorescence of the pyrimidine analogs is quenched; cleavage of the alpha-beta-phosphoryl bond of the utp analog produces abo ...	1979	387781
primary plate identification of group a beta-hemolytic streptococci utilizing a two-disk technique.	a two-disk system is described which allows primary plate identification of group a beta-hemolytic streptococci. group a beta-hemolytic streptococci could be visualized on primary throat culture plates by using trimethoprim-sulfamethoxazole to inhibit normal flora. in the heavily inoculated area of trypticase soy agar plates containing 5% sheep blood, a 25-microgram/ml trimethoprim-sulfamethoxazole disk was placed contiguous to a 0.04-u bacitracin disk. a total of 259 throat specimens were exami ...	1979	387811
studies on conformational changes in f-actin of glycerinated muscle fibers during relaxation by means of polarized ultraviolet fluorescence microscopy.	by means of polarized ultraviolet fluorescence microscopy the conformational changes of f-actin occuring in glycerinated muscle fibers of rabbit and barnacle (balanus rostratus hock.) under the influence of adenosine triphosphate in the presence of ethylene glycol bis(beta-amino-ethyl ether)-n,n'-tetraacetic acid were discovered. these changes seem to be located near the surface of the globules thus hampering the penetration of univalent iones and neutral molecules into the f-actin macromolecule ...	1979	470613
lung compliance and lung morphology following artificial ventilation in the premature and full-term rabbit neonate.	rabbit neonates delivered on day 27--30 of gestation were subjected to intermittent positive pressure ventilation (ippv) for 60 min. tidal volume was standardized to 10 ml/kg, and the insufflation pressure required to maintain this tidal volume was recorded. the quasistatic compliance of the lung-thorax system, corrected for variations in body weight, was significantly lower in animals delivered on day 27--28 than in those delivered on day 29--30. immature animals with low lung-thorax complianc ...	1979	394314
[cyst formation by methanosarcina].	the morphology of a coccoid, methane producing bacterium growing on acetate was studied. the organism is capable of forming morphologically differentiated cells, nicrocysts, whose structure resembles that of bacterial surviving cells. the organism from peculiar macrocysts in the enrichment culture. in its other characteristics, the organism is similar to methanococcus mazei. however, it clasibied as methanosarcina, biotype 3, due to the characteristic formation of multicellular pseudococci.	1979	470629
consequences of ca2+ deficiency on macromolecular synthesis and adenylate energy charge in yersinia pestis.	a 37 but not 26 degrees c virulent yersinia pestis is known to require at least 2.5 mm ca2+ for growth; this requirement is potentiated by mg2+. after shift of log-phase cells (doubling time of 2 h) from 26 to 37 degrees c in ca2+-deficient medium, shutoff of net ribonucleic acid synthesis preceded that of protein and cell mass. with 2.5 mm mg2+, about two doublings in cell mass and number occurred before restriction with synthesis of sufficient deoxyribonucleic acid to account for initiation an ...	1979	479109
purification and chemical characterization of antigens from sheep erythrocytes.	a mixture of glycoproteins and glycolipids was solubilized from sheep erythrocytes membranes under the effect of high ionic strength (2 m nacl, 0.5 m tris). several antigenic fractions could be purified from the mixture using gel filtration on sephadex g-200 and block electrophoresis on pevikon c870; two fractions were found to raise antibodies in a primary reaction and these antibodies effectively sensitized erythrocytes to lysis by complement. the majority of other fractions elicited a weaker ...	1979	511033
the association of var1 with the 38 s mitochondrial ribosomal subunit in yeast.		1979	387793
api and minitek systems in identification of clinical isolates of anaerobic gram-negative bacilli and clostridium species.	a comparison of the api and minitek methods of biochemical testing was made on a variety of anaerobic bacteria. although api and minitek results were not compared to more standardized or conventional procedures of identification, multiple repeat testing of the two systems was done on routine clinical isolates and known organisms to determine (i) whether the reactions were reliably consistent, (ii) the ease of reading the two systems with respect to the frequency of questionable results, and (iii ...	1979	387809
[the molecular biology of aging -- 15: structure and function of the genetic apparatus in aging. ii. synthesis and metabolism of rna].	with aging in different organs there are similar or tissue specific changes of the ribonucleic acids in respect of the quantity, the spectrum of different rna species and the metabolism of rna. among these processes the template function of the chromatin and the behaviour of the rna polymerases are important influencing factors. in aging the sensitivity of the rna synthesis against hormonal stimulation is decreased in the most cases. a survey about the results of many in vivo and in vitro experi ...	1979	395770
[effects of ionizing radiations on the ultrastructure of bursa of fabricius].	the alterations induced in the lymphoid and epitelial cells of the bursa of fabricius in chicks exposed at different doses of gamma rays mainly occur during the interfase. the extent of these alterations appears reduced in comparison with that observed in the chick thymus treated in the same way.	1979	518763
genetic modification of macrophage functions in relation to antibody responsiveness and resistance to infection.		1979	397751
[bactericidal action of formalin on the causative agent of plague].	ten per cent neutral formalin in a ratio 1 : 20 was demonstrated to be useful as a desinfecting and fixing substance in pathohistological examinations of organs and tissues animals infected with the causative agent of plague. with test-objects' volume of 1.0 cm3 the optimal period of exposure providing a permanent bactericidal effect is 24 hours, with volumes of 1.5 and 2.0 cm3-2 days. the fixing effect of formalin on tissues is exerted in 3-4 days.	1979	378193
isolation of pathogens other than yersinia pestis during plague investigations.	from 1975 to 1978, 37 isolates of pasteurella multocida, 1 of salmonella enteriditis, and 5 of francisella tularensis were recovered from 42 mammalian specimens and 1 flea pool submitted for examination for evidence of infection with yersinia pestis. most of the specimens were collected during investigations of either a human plague infection or a reported epizootic among rodent populations. all specimens were of species regularly or occasionally involved in plague or tularemia cycles in nature ...	1979	392123
[bacteriophagy and bacteriocinogeny of yersinia enterocolitica].		1979	375639
unusual pattern of nucleoside polyphosphate hydrolysis by the acid phosphatase (optimum ph = 2.5) of escherichia coli.		1979	378222