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hydrophobic membrane thickness and lipid-protein interactions of the leucine transport system of lactococcus lactis.the effect of the phospholipid acyl chain carbon number on the activity of the branched-chain amino acid transport system of lactococcus lactis has been investigated. major fatty acids identified in a total lipid extract of l. lactis membranes are palmitic acid (16:0), oleic acid (18:1) and the cyclopropane-ring containing lactobacillic acid (19 delta). l. lactis membrane vesicles were fused with liposomes prepared from equimolar mixtures of synthetic phosphatidylethanolamine (pe) and phosphatid ...19911905573
acquired immunity and epidemiology of schistosoma haematobium.human immune responses to schistosome infection have been characterized in detail. but there has been controversy over the relative importance of ecological factors (variation in exposure to infection) and immunological factors (acquired immunity) in determining the relationships between levels of infection and age typically found in areas where infection is endemic. independent effects of exposure and age on the rates of reinfection with schistosoma haematobium after chemotherapy have been demo ...19911905786
bacterial entry into eukaryotic cells. 19911905978
entry of l. monocytogenes into cells is mediated by internalin, a repeat protein reminiscent of surface antigens from gram-positive cocci.we report the identification of a previously unknown gene, inla, which is necessary for the gram-positive intracellular pathogen listeria monocytogenes to invade cultured epithelial cells. the inla region was localized by transposon mutagenesis, cloned, and sequenced. inla was introduced into listeria innocua and shown to confer on this normally noninvasive species the ability to enter cells. sequencing of inla predicts an 80 kd protein, internalin. two-thirds of internalin is made up of two reg ...19911905979
[anatomopathologic diagnosis of parasitosis in congo].in the part ten years, 9,650 anatomopathologic examinations have been carried out in the national laboratory of histopathology for public health in brazzaville: 250 cases of parasitic infestation were diagnosed. in order of frequency were noted; 144 cases of bilharzia due to schistosoma haematobium with 75 genito-urinary localisations and 51 appendicular cases, 31 cases of onchocercosis with a majority of subcutaneous nodules (17), 17 cases of digestive helminthiasis all locate in the ileo-caeca ...19911905986
comparison of 8-hydroxydeoxyguanosine and 5-hydroxymethyluracil as products of oxidative dna damage. 19911906231
[study of the dependence of gene expression of plague pathogen plasmid 65md on the host bacterium genome].the conjugative cointegrate containing yersinia pestis 65 md plasmid coding for the production of traction i antigen and mouse toxin has been transferred into yersinia pseudotuberculosis, yersinia enterocolitica and escherichia coli cells. analysis of the transconjugants obtained has confirmed the connection of the genetical determinants for the mentioned bacterial products with the 65 md plasmid. the similar level of fra and tox-genes expression has been found in yersinia cells while fraction i ...19911906986
the effect of pediococcus damnosus and pediococcus pentosaceus on the growth of pathogens in minced meat.the antibacterial effects of one strain of pediococcus damnosus and two strains of pediococcus pentosacaeus against clostridium perfringens, listeria monocytogenes, salmonella infantis and yersinia enterocolitica were investigated. growth inhibition studies were conducted in juice from minced meat incubated at +6 degrees c and +15 degrees c for various periods after the inoculation with pediococci. inhibitory effects were seen for all bacteria tested.19911907475
survival of yersinia enterocolitica and escherichia coli in spring water.survival of pure and mixed cultures of yersinia enterocolitica and escherichia coli in sterile spring water stored at 4 degrees c was evaluated. y. enterocolitica increased two or three logs during the first 3 weeks of incubation, and at the end of 64 weeks viable cells in numbers corresponding to the initial inoculum level were still detectable. however, after 1 week of incubation, the number of e. coli in water started to decrease and in 13 weeks time no e. coli was detected. more rapid decrea ...19911911089
cloning, sequencing, and expression of the p-protein gene (phea) of pseudomonas stutzeri in escherichia coli: implications for evolutionary relationships in phenylalanine biosynthesis.the phea gene encoding the bifunctional p-protein (chorismate mutase:prephenate dehydratase) was cloned from pseudomonas stutzeri and sequenced. this is the first gene of phenylalanine biosynthesis to be cloned and sequenced from pseudomonas. the phea gene was expressed in escherichia coli, allowing complementation of an e. coli phea auxotroph. the enzymic and physical properties of the p-protein from a recombinant e. coli auxotroph expressing the phea gene were identical to those of the native ...19911919506
yersinia infected blood. 19911923099
[approach to evaluation of the indicators of yersinia infections in reactive and rheumatoid arthritis].a total of 140 patients with reactive arthritis due to yersinia infection were under observation for 2-10 years. a group of 104 patients with erosive rheumatoid arthritis served as control for analysis of the results of bacteriological and serological studies. the bacteriological analysis of the feces, urine, smears of the feces and blood were made repeatedly. as established the articular syndrome in reactive arthrosis has its specific features depending on the nature of the pathological process ...19911925260
basic fibroblast growth factor in human melanoma.basic fibroblast growth factor (bfgf) is a major factor contributing to human melanoma cell growth. bfgf is produced constitutively by cells from each stage of the disease, but not by normal melanocytes, although the latter cells are dependent on the factor for growth in vitro. two lines of evidence suggest that bfgf functions in an autocrine manner in melanoma: (1) inhibition of bfgf activity by bfgf-specific antibodies or antisense sequences suppresses melanoma cell growth in vitro; and (2) re ...19911931440
evaluation of methods for examination of antibody response after infection with yersinia enterocolitica o:3. 19911935074
yersinia enterocolitica surveillance in belgium (1979-1989). 19911935075
immune response to flagellar antigens in human infections with yersinia enterocolitica. 19911935076
immunoglobulin isotypes produced by mice experimentally infected with yersinia sp. 19911935077
yersinia enterocolitica: antigenic components with diagnostic potential. 19911935078
the v antigen of yersiniae: an overview. 19911935079
colonization of yersinia enterocolitica serovar o3 in the intestines of mice. 19911935081
experimental infection of mice with yersinia strains bearing or not bearing the virulence-associated plasmid. 19911935082
uptake of killed yersinia enterocolitica cells by epithelial cells in the peyer's patches of mice. 19911935083
comparative evaluation of various media for the detection of pathogenic yersinia enterocolitica. 19911935084
development of antisera to detect virulent yersinia enterocolitica, shigella and escherichia coli enteroinvasive. 19911935085
the epidemiology of yersinia enterocolitica infection in the british isles 1983-1988. 19911935086
adhesion of yersiniae to rabbit intestinal constituents: role of outer membrane protein yada and modulation by intestinal mucus. 19911935087
expression of the virulence plasmid-determined protein yop1 and hela cell invasiveness of yersinia enterocolitica o:3. 19911935088
phenotypic characterization and virulence of o8 yersinia strains isolated in europe. 19911935089
molecular cloning of yersinia enterocolitica o:3 rfb region: evidence that temperature regulates the rfb region at the transcriptional level. 19911935091
preparation of monoclonal antibody to v antigen from yersinia pestis. 19911935094
beta-lactamases of strains of yersinia enterocolitica biovar 6 isolated from foods. 19911935096
antimicrobial susceptibility of pathogenic yersinia enterocolitica strains in the british isles. 19911935097
isolation of yersinia from the resected appendix. 19911935098
comparative isolation of yersinia spp. from avian wildlife by different methods. 19911935099
yersinia enterocolitica bacteremia: an analysis of thirty-six patients in denmark and a review of the literature. 19911935100
yersinia enterocolitica and other enteric pathogens in patients with suspected appendicitis. 19911935101
new observations on acute and chronic disease associated with yersinia enterocolitica infection. a 10-year follow-up study on 458 hospitalized patients. 19911935102
isolation of yersinia from appendices of patients with acute appendicitis. 19911935104
invasive disease due to yersinia enterocolitica in children with beta-thalassemia major. 19911935105
yersinia enterocolitica o:3 antibodies in slaughterhouse employees, veterinarians, and military recruits. occupational exposure to pigs as a risk factor for yersiniosis. 19911935110
isolation of yersiniae from sewage. 19911935111
urease-negative strains of yersinia enterocolitica and related species isolated from human and nonhuman sources. 19911935112
direct isolation of yersinia enterocolitica from stool specimens of patients with intestinal disorders. 19911935114
occurrence of yersinia enterocolitica in pork products from northern taiwan. 19911935115
colonization in the tonsils of swine by yersinia enterocolitica. 19911935116
enteropathogenic yersinia enterocolitica and organ-specific autoimmune diseases in man. 19911935118
a molecular basis for antigen homologies of thyroid epithelial cells and plasmid-encoded proteins of enteropathogenic yersinia enterocolitica. 19911935119
immunoblot analysis of antibody response to yersinia enterocolitica in patients with reactive arthritis and enterocolitis. 19911935120
cross-reacting protein antigen of yersinia enterocolitica is a heat shock protein. 19911935121
the serological relationship between yersinia enterocolitica o9 and escherichia coli o157 using sera from patients with yersiniosis and haemolytic uraemic syndrome.sera from patients with yersiniosis, shown to contain antibodies to yersinia enterocolitica o9; and sera from patients with haemolytic uraemic syndrome (hus) caused by escherichia coli o157, were used to investigate serological cross-reactions between y. enterocolitica o9 and e. coli o157. lipopolysaccharide (lps) was isolated from strains of y. enterocolitica o9 and e. coli o157 and reacted with sera by immunoblotting and elisa. sera from patients with hus contained antibodies to the lps of e. ...19911936156
convenient agarose medium for simultaneous determination of the low-calcium response and congo red binding by virulent strains of yersinia enterocolitica.a simple, efficient method for identification and differentiation of yersinia enterocolitica containing virulent plasmid-bearing clones is described. the method is based on temperature of incubation and the low calcium response of the organism in an agarose congo red medium.19911939595
long-term yersiniosis surveillance project in czechoslovakia.the paper presents an epidemiological analysis of 8,232 cases of yersiniosis caused by y. enterocolitica 03 over 1972-1988 as reported by hygienic stations. the steady epidemiological characteristics of yersiniosis were the prevalence of children and boys and a typical seasonal pattern with differences between the czech and slovak republics. in the czech republic, there were several incidence peaks following, when summarized, the incidence curve of other alimentary infections, whereas in the slo ...19911940332
expression in vivo of additional plasmid-mediated proteins during intestinal infection with yersinia enterocolitica serotype o8.the decisive aspect of yersinia enterocolitica virulence in vivo is the ability of the plasmid-bearing bacteria to resist the immune response within the host tissue. the expression of plasmid-mediated virulence proteins was investigated in the intestinal lumen and in the peyer's patches of infected mice. three novel plasmid-mediated outer-membrane proteins have been identified with antisera raised against bacteria grown in vivo. when the bacteria were grown in the intestinal lumen, all plasmid-c ...19911941997
[yersiniosis in a general hospital in the basque country (1984-1989). clinical and epidemiological aspects].the features of the diseases caused by yersinia have not been properly evaluated in the basque country. the present study was performed to assess the incidence and consequences of this infection.19911943291
[yersinia enterocolitica and the thyroid gland]. 19911946302
in the blink of an eye: real-time stimulus factors in delay and trace conditioning of the rabbit's nictitating membrane response.since pavlov, theories of conditioning have assumed that cr evocation is governed by a series of internal stimuli generated by the cs. this hypothesis was tested in conditioning of the rabbit's nictitating membrane (nm) response by attempting to manipulate the internal sequence through truncating a delay cs and extending a trace cs on test trials. these perturbations of cs duration produced large deficits in cr likelihood and smaller alterations in the cr's time course. as predicted by many mode ...19911947201
fatal yersinia enterocolitica (serotype 0:5,27) sepsis after blood transfusion.septicemia is a rare complication of blood transfusion. this is probably primarily due to the use of sealed disposable containers for blood collection and the storage of red cell-containing components at 4 degrees c. however, despite these measures, septicemia due to blood transfusion continues to occur. we report here a fatal case of yersinia enterocolitica septicemia due to a contaminated unit of red cells which was collected from an apparently healthy, asymptomatic blood donor. the organism g ...19911949705
[the boosting of yersinia enterocolitica virulence during passage through infusorians and mammalian macrophages (comparative research)].selective changes in y. enterocolitica virulence have been made in experiments on eukaryotic cells, infusoria, and peritoneal macrophages, used as models. in parallel experiments with the passage of yersinia through infusoria and mammalian macrophages an analogy to the processes of phagocytosis has been established.19911950257
jaw protruder muscles and condylar cartilage growth in the rat.many studies have explored the role of the protrusive musculature in promoting growth at the condylar cartilage and the overall lengthening of the lower jaw, with emphasis on the lateral pterygoid muscle (lpm). the largely anteroposterior orientation of the superficial part of the masseter muscle (sm) in the rat suggests that it may also function as a protruder of the lower jaw. accordingly, it is possible that the action of the sm may play a part in the regulation of growth of the condylar cart ...19911951196
dogs as sentinels for lyme disease in massachusetts.an investigation of the relationship between incident human cases of lyme disease and seroprevalence of antibodies to b. burgdorferi in dogs was undertaken in order to determine whether dogs might serve as sentinels for lyme disease.19911951802
[cytological examination of urethral and endocervical smears in the diagnosis of infections].cytologic studies of smears from 130 women suffering from various diseases, including 61 pregnant patients with gestoses, have shown structural changes of the cells in the smears from the endocervix and urethra, that permitted the diagnosis of mycoplasma infection in 43.8% of patients, chlamydia infection, 52.3%, and herpes simplex in 72.3% of patients; in 63.9% of patients these infections were combined. cytologic studies may be useful in the tentative diagnosis of urogenital infections, includ ...19911951977
failure of beta-lactam antibiotics and marked efficacy of fluoroquinolones in treatment of murine yersinia pseudotuberculosis infection.the treatment of yersiniosis by beta-lactams is questionable considering the proven failure of newer beta-lactams for treating murine yersinia enterocolitica infection. another modality of experimental treatment was performed with a virulent strain of y. pseudotuberculosis (nonproducer of beta-lactamase) highly susceptible (in terms of mics) to amoxicillin, cefotaxime, ceftriaxone, imipenem, doxycycline, gentamicin, and ofloxacin. the in vivo comparative efficacy of these drugs was evaluated in ...19911952849
effects of yersinia enterocolitica infection on rabbit intestinal and colonic goblet cells and mucin: morphometrics, histochemistry, and biochemistry.the effects of yersinia enterocolitica on intestinal goblet cells were investigated in new zealand white rabbits. animals infected with y enterocolitica were compared with weight matched and pair fed controls. goblet cell hyperplasia developed in the distal small intestine of infected rabbits on day 1, in the mid small intestine on day 3, and in the upper small intestine on day 6. in all regions hyperplasia persisted throughout the 14 day study. the degree of hyperplasia was greater in the dista ...19911955167
ymoa, a yersinia enterocolitica chromosomal gene modulating the expression of virulence functions.the virulence functions of yersinia enterocolitica include the pyv-encoded yop proteins and yada adhesin as well as the chromosome-encoded enterotoxin, yst. the yop and yada genes form a temperature-activated regulon controlled by the transcriptional activator virf. gene virf, also localized on pyv, is itself thermoinduced in the absence of other pyv genes. the enterotoxin yst gene is silent in some collection strains including strain w22703. this paper describes two tn5-tc1 chromosomal insertio ...19911956283
[bacterial ileocecitis, a "new" disease].786 patients with suspected acute appendicitis or appendiceal mass were examined by ultrasonography to distinguish appendicitis from bacterial enteritis. 533 of these patients were described before. in 91 (11.6%) ultrasonography revealed the characteristic picture associated with bacterial enteritis of the ileocaecal region-enlarged mesenteric lymph nodes and mural thickening of the terminal ileum and caecum--but no image of an inflamed appendix. in 64 of these a bacterial infection was confirme ...19911956444
[histiocytic necrotizing lymphadenitis; kikuchi's disease]. 19911956451
[yersinia enterocolitica infections; clinical and histological characteristics, diagnosis and therapy]. 19911956456
[clinical findings and diagnosis of yersinia enterocolitica infections; a retrospective study in friesland].the clinical data of 97 patients with yersinia enterocolitica infection during 1989 were evaluated. the diagnosis was made by positive culture, serology and/or detection of yersinia antigens in biopsies. the enteric form (enteritis, abdominal syndrome, pseudo-appendicitis, ileitis and colitis) occurred in 66% of all patients, 10 (10%) had an extramesenteric form, 22 had arthritis and 6 had erythema nodosum. the mean age was 33.6 (sd 19.4) years. abdominal pain was the syndrome most frequently ob ...19911956458
antibody to hepatitis c (anti c 100-3) in french hemophiliacs.486 patients followed in four french hemophilia centres were tested for antibody to hepatitis c virus c100-3 recombinant protein. on samples collected in 1989, the overall incidence of anti-c 100-3 positivity was 66%. none of the 27 patients only exposed to solvent-detergent treated factor viii or ix concentrates had c 100-3 antibodies. there was no difference according to the type of hemophilia nor to its severity. serological follow-up from 1985 to 1989 was carried out on 51 patients. two thir ...19911956764
late complications after a yersinia enterocolitica epidemic: a follow up study.ninety four finnish conscripts were affected by a yersinia enterocolitica epidemic in 1973. thirteen years later 75 men completed a questionnaire about their present health. one half had no health problems, and the most common complaints in the other subjects were musculoskeletal disorders. sixteen men wanted to be re-examined. in three cases a chronic connective tissue disease was diagnosed. two men had ankylosing spondylitis. the most notable results of this study were (a) the fairly low numbe ...19911958092
monoclonal antibodies against yersinia enterocolitica common antigen produced by immunization with immunoprecipitates.crossed immunoelectrophoresis was applied to purify y. enterocolitica common antigen by precipitation with monospecific rabbit anti-p. aeruginosa ca antibody. monoclonal antibodies against y. enterocolitica ca were then raised by immunization of mice with these immunoprecipitates. this method provides the possibility of producing a panel of anti-ca monoclonal antibodies from a large number of bacterial species.19911958353
pyomyositis in patients with diabetes mellitus.pyomyositis is a pyogenic infection of skeletal muscle that is endemic in the tropics and is being recognized with increasing frequency in temperate climates. we report two cases of nonendemic pyomyositis in patients with diabetes mellitus. a review of the literature suggests that diabetes mellitus may be an important risk factor for the development of pyomyositis. possible mechanisms of this association are discussed.19911962087
evidence that arachidonic acid influences hen granulosa cell steroidogenesis and plasminogen activator activity by a protein kinase c-independent mechanism.we recently proposed that arachidonic acid serves as a second messenger within granulosa cells from the largest preovulatory follicle of the hen. the present studies were conducted to determine whether the inhibitory effects of arachidonic acid on lh-induced camp accumulation and on the ability of cells to convert 25-hydroxycholesterol to progesterone are mediated via the protein kinase c pathway. furthermore, we determined the effects of arachidonic acid on plasminogen activator activity in gra ...19901963326
[the presence of the yersinia group in environmental factors, food and some animal species].in a broad bacteriologic investigation, including more than 3,000 examination of domestic animals (porcines, bovines), fish, food (milk, ice cream), surface waters and soil, 27 strains of yersinia enterocolitica were isolated. of them 22 belonged to the o3(-8); o5(-6); o5,7,8(-2); o6(-2); o7(-2); o9(-2) serotypes, and 5 could not be serotyped, but were included in the biotype i. the strains isolated from fish, food and environment had a biochemical and/or serologic behaviour similar to that usua ...19901966342
[viral infections associated with intestinal invagination].intestinal invagination is rather frequently associated with local tumors, adenovirus infections, and occasionally with yersinia enterocolitica. however, in many cases the etiology is not known. we have studied 88 children with intestinal invagination in whom cellular cultures of hep 2 and pulmonary fibroblasts of human embryo have been inoculated with a fecal sample. the clinical reports have been reviewed retrospectively. in 19 patients (21.59%) we obtained an adenovirus and in 12 patients (13 ...19901967100
relationship between somatostatin and growth hormone messenger ribonucleic acid in human pituitary adenomas: an in-situ hybridization histochemistry study.we have used quantitative in-situ hybridization histochemistry to assess the somatostatin (srih) and gh messenger ribonucleic acid (mrna) content of 81 pituitary adenomas. srih mrna was found in the absence of gh mrna in only one tumour and in the five cases in which gh and srih mrna were both present, srih mrna prevalence was approximately two orders of magnitude less than gh mrna. however, no direct correlation between gh mrna, srih mrna and circulating gh levels was evident at the time of sur ...19901973086
epidemiological typing of yersinia enterocolitica by analysis of restriction fragment length polymorphisms with a cloned ribosomal rna gene.intra-species restriction fragment length polymorphisms (rflps) of yersinia enterocolitica were detected in assays with a cloned dna fragment from legionella pneumophila that included the 16s and 23s rrna genes. by use of this method it was possible to identify different rflp types within biogroups/serogroups which were indistinguishable by other means. thus the 37 biogroup iv/serogroup o3 strains isolated worldwide from pig carcasses, pork and human patients, were subdivided into five different ...19901973736
bacterial ileocaecitis and appendicitis. 19901975035
detection of pathogenic yersinia enterocolitica by the polymerase chain reaction. 19901975880
pathogenic escherichia coli, yersinia enterocolitica, and vibrio parahaemolyticus. 19901977991
correlation between ribosomal dna polymorphism and electrophoretic enzyme polymorphism in yersinia.ribosomal dna (rdna) polymorphism was compared with electrophoretic enzyme polymorphism for the intra- and interspecies differentiation of yersinia enterocolitica, y. pseudotuberculosis, y. intermedia, y. aldovae, y. frederiksenii and y. kristensenii. dna from 90 strains previously classified into six zymotypes (y. enterocolitica and y. frederiksenii) and into distinct enzyme electrophoretic patterns (the four other species) was digested with ecori or hindiii and analysed by southern blotting. t ...19901979806
a cloned chromosomal dna fragment which differentiates yersinia pestis from yersinia pseudotuberculosis and yersinia enterocolitica.chromosomal dna from reference yersinia strains was digested individually with 9 restriction endonucleases. dna fragments were separated and analyzed by electrophoresis through agarose gels. the clearest fragment patterns were obtained when ecori was employed. the y. pestis fragment pattern obtained after the use of this enzyme showed the presence of a unique dna fragment with molecular mass 1400 bp. this dna fragment was cloned, purified, labeled with 32p and then used to probe ecori digests of ...19901980253
application of the polymerase chain reaction and immunofluorescence techniques to the detection of bacteria in yersinia-triggered reactive arthritis.leukocytes in synovial fluid and peripheral blood samples from patients with yersinia-triggered reactive arthritis were analyzed after dna amplification using the polymerase chain reaction. the primers applied were specific for the virulence plasmid-coded 1cre genes of yersinia enterocolitica o:3 and yersinia pseudotuberculosis iii. no yersinia dna was observed within the synovial fluid cells or peripheral blood cells by polymerase chain reaction techniques. however, yersinia antigens were detec ...19911984781
interactions between yersinia enterocolitica and rabbit ileal mucus: growth, adhesion, penetration, and subsequent changes in surface hydrophobicity and ability to adhere to ileal brush border membrane vesicles.interactions between yersinia enterocolitica and rabbit ileal mucus were examined. strains carrying the yersinia virulence plasmid, pyv, adhered to crude mucus but not to intestinal luminal contents that had been immobilized on polystyrene. using an y. enterocolitica o:9 mutant in which the yada gene (formerly called yopa), encoding the high-molecular-weight outer membrane protein yada (formerly called protein p1 or yop1), had been inactivated and an escherichia coli strain carrying the cloned y ...19911987040
combined use of released proteins and lipopolysaccharide in enzyme-linked immunosorbent assay for serologic screening of yersinia infections.an elisa for the screening of serum antibodies to yersinia species was developed using plasmid-encoded released proteins of yersinia enterocolitica o:8 and lipopolysaccharide of y. enterocolitica o:3 as a combined antigen. of 43 sera from patients infected with one of six different yersinia serotypes, 40 (93%) were positive in this assay. when tested using six serotype-specific elisas with the corresponding yersinia bacteria as antigens, 38 (88%) were positive. this screening elisa detects antib ...19911988526
the omph gene of yersinia enterocolitica: cloning, sequencing, expression, and comparison with known enterobacterial omph sequences.we have recently described a previously uncharacterized outer membrane protein of salmonella typhimurium and escherichia coli and cloned and sequenced the corresponding gene, the omph gene, of s. typhimurium (p. koski, m. rhen, j. kantele, and m. vaara, j. biol. chem. 264:18973-18980, 1989). we report here the cloning, sequencing, and expression of the corresponding gene of yersinia enterocolitica. it is significantly homologous to the omph genes of e. coli and s. typhimurium (homology percentag ...19911991717
cationic antigens as mediators of inflammation.electrical charge is an important determinant of antigen deposition in tissue. cationic antigens can bind to anionic sites found in many organs. the major focus of interest has been the renal glomerulus and the articular joint. experimental models of immune complex glomerulonephritis and allergic arthritis were established with chemically cationized proteins. more recently the concept has been extended to natural cationic proteins and human disease. the histones were shown to be potent initiator ...19911993113
production and characterization of a monoclonal antibody specific for enterohemorrhagic escherichia coli of serotypes o157:h7 and o26:h11.a monoclonal antibody (mab 4e8c12) specific for escherichia coli o157:h7 and o26:h11 was produced by immunizing balb/c mice with a rough strain of e. coli o157:h7. the antibody reacted strongly by a direct enzyme-linked immunosorbent assay with each of 36 strains of e. coli o157:h7. no cross-reactivity was observed with strains of salmonella spp., yersinia enterocolitica, shigella dysenteriae, proteus spp., escherichia hermanii, klebsiella pneumoniae, campylobacter jejuni, serratia marcescens, c ...19911993773
yersinia enterocolitica o:3: an emerging cause of pediatric gastroenteritis in the united states. the yersinia enterocolitica collaborative study group.after an outbreak of yersinia enterocolitica infections among black children in atlanta, a seven-hospital study was conducted to determine the importance of this pathogen in other communities with large black populations. of 4841 stool specimens from patients with gastroenteritis examined between november 1989 and january 1990, y. enterocolitica, shigella, campylobacter, and salmonella were identified in 38, 49, 60, and 98 specimens, respectively; 34 (92%) of 37 y. enterocolitica isolates were s ...19911995741
[liver abscesses due to yersinia enterocolitica].a 41-year-old man with type ii diabetes for the past five years had for three weeks been suffering from high fever (up to 40 degrees), feeling of pressure in the upper abdomen, loss of weight, lack of appetite and increasing weakness. ultrasound examination as an out-patient was suspicious of diffuse liver metastases from an unknown primary tumour. ultrasonography and computed tomography after hospitalization suggested multiple liver abscesses. fine-needle biopsy grew yersinia enterocolitica. in ...19911997307
humoral and cellular defense against intestinal murine infection with yersinia enterocolitica.the role of phagocytes and the complement system as potential host defense mechanisms against bacterial infection were studied in mice with two isogenic strains of yersinia enterocolitica serotype o8 differing in pathogenicity because of differences in plasmid content. complement depletion in mice by intraperitoneal injection of cobra venom factor did not affect the course of colonization of the intestinal tissue by each strain, indicating that in mice complement is not essential for the elimina ...19911997413
bacterial antigens in synovial biopsy specimens in yersinia triggered reactive arthritis.non-viable structures of yersinia enterocolitica o:3 were shown at the site of inflammation within mononuclear cells in the synovial membrane of eight out of 10 patients with yersinia triggered reactive arthritis. an avidin-biotin-peroxidase complex method, with a rabbit antiserum specific for y enterocolitica o:3, was used to visualise yersinia structures. all 13 control samples were negative except for one with non-specific mast cell staining. the findings emphasise the significance of foreign ...19911998396
intestinal permeability in patients with yersinia triggered reactive arthritis.the passive intestinal permeability of patients with yersinia triggered reactive arthritis was studied using different sized polyethylene glycols (pegs) contained in a mixture of peg 400 and peg 1000. the investigation was carried out at least one year after the onset of yersinia infection, and patients had neither acute gastrointestinal nor joint symptoms. the control groups included patients with uncomplicated yersiniosis as well as healthy subjects who were either hla-b27 positive or negative ...19911998397
secretion of hybrid proteins by the yersinia yop export system.after incubation at 37 degrees c in the absence of ca2+ ions, pathogenic strains of yersinia spp. release large amounts of a set of plasmid-encoded proteins called yops. the secretion of these proteins, involved in pathogenicity, occurs via a mechanism that involves neither the removal of a signal sequence nor the recognition of a c-terminal domain. analysis of deletion mutants allowed the secretion recognition domain to be localized within the 48 n-terminal amino acids of protein yoph, within t ...19911999387
yersinia enterocolitica septicaemia in the absence of gastro-intestinal symptoms. 19912002226
comparison of crossed immunoelectrophoresis, enzyme-linked immunosorbent assays, and tube agglutination for serodiagnosis of yersinia enterocolitica serotype o:3 infection.antibodies against yersinia enterocolitica serotype o:3 were measured by crossed immunoelectrophoresis (xie) using whole-cell sonic extract as antigen and by enzyme-linked immunosorbent assays (elisas) using either purified lipopolysaccharide or whole formalinized cells expressing virulence plasmid-encoded surface antigens (pyv+ cells). the results were compared with those obtained with the standard tube agglutination method. sera from three groups of people were examined by using these assays. ...19912007638
therapy for acute infectious diarrhea in children.this article reviews current recommendations of therapy with antidiarrheal compounds and antimicrobial agents for acute infectious diarrhea in children. in most infants and children with acute infectious diarrhea, treatment with antidiarrheal compounds is not indicated. many of these compounds interfere with identification of enteropathogens in stool specimens, and the antimotility class has an overdose potential. antimicrobial therapy is given to reduce symptoms and to prevent the spread of inf ...19912007952
blood transfusion acquired yersinia enterocolitica sepsis: two cases. 19912011294
from the centers for disease control. yersinia enterocolitica bacteremia and endotoxin shock associated with red blood cell transfusions--united states, 1991. 19912013941
comparative study of a dna hybridization method and two isolation procedures for detection of yersinia enterocolitica o:3 in naturally contaminated pork products.we compared a dna-dna hybridization assay, using a synthetically produced oligonucleotide probe, and two conventional isolation procedures (methods a and b) with regard to their relative efficiency in detecting yersinia enterocolitica o:3 in naturally contaminated pork products. method a was as described by wauters et al. (appl. environ. microbiol. 54:851-854, 1988). method b has been recommended by the nordic committee on food analysis (method no. 117, 1987). the genetic probe was used in a col ...19912014988
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