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effects of iron and temperature on shiga-like toxin i production by escherichia coli.iron is known to depress shiga toxin production by shigella dysenteriae 1, and temperature has been shown to regulate several genes required for shigella invasiveness. in this study, the influence of iron and temperature on regulation of a highly related toxin, shiga-like toxin i (slt-i) of enterohemorrhagic escherichia coli, was examined in strains lysogenic for the toxin-converting coliphage 933j and in strains carrying the cloned slt-i genes on a high-copy-number plasmid vector. for compariso ...19883121508
analbuminaemia: a natural model of metabolic compensatory systems.important clinical signs are usually not present in analbuminaemia, a congenital condition inherited as an autosomal recessive trait, but several biochemical alterations in proteins, cholesterol, phospholipids and plasma beta lipoproteins have been observed. we studied two sibs, r.u. and r.r., with this disease and observed a striking increase in the variables mentioned above as well as a high ldl fraction with concomitant increase in apo b; increases in hdl3 and apo a-i and a-ii levels were als ...20113126352
[experience with the co2 laser in oral surgery]. 20113126482
cytogenetic abnormalities among spontaneously aborted previable fetuses.we have reviewed spontaneously aborted fetuses of 9 to 20 developmental weeks. all fetuses with either external or internal developmental defects and those with maternal history of repeated spontaneous abortion were studied cytogenetically. among 723 fetuses the cytogenetically proven prevalence of chromosome abnormalities was 5.8%. inclusion of suspected chromosome abnormality based on morphologic findings resulted in an overall prevalence of only 7.1%. this prevalence and restricted spectrum o ...20113130845
pure red cell aplasia with hypogammaglobulinemia appearing after thymectomy: a possible role for serum and cellular factors. 20093131206
characterization of the protein expressed in escherichia coli by a recombinant plasmid containing the bacillus megaterium cytochrome p-450bm-3 gene.in two previous reports (narhi lo, fulco aj, j. biol. chem. 261: 7160-7169, 1986; ibid., 262: 6683-6690, 1987) we described the characterization of a catalytically self-sufficient 119,000-dalton p-450 cytochrome that was induced by barbiturates in bacillus megaterium. in the presence of nadph and o2, this polypeptide (cytochrome p-450bm-3) catalyzed the hydroxylation of long-chain fatty acids without the aid of any other protein. the gene encoding this unique monooxygenase was cloned into escher ...19883131661
delays in diagnosing and treating bladder cancer. 20113133024
etiology of carbon dioxide retention at rest and during exercise in chronic airflow obstruction.the purpose of this project was to better define factors that influence the resting paco2 and the change in the paco2 from rest to exercise in patients with moderate to severe chronic airflow obstruction. pulmonary function testing, symptom-limited exercise tests using arterial catheter lines, and resting ventilatory and mouth occlusion pressure responses to hypercapnia and hypoxia were obtained in 19 patients (mean fev1 = 1.07 +/- .50 l). the resting paco2 was closely related to the resting hyp ...20113133164
micronucleus assay in human fibroblasts: a measure of spontaneous chromosomal instability and mutagen hypersensitivity.by comparing fibroblast strains derived from individuals exhibiting chromosome instability and/or mutagen hypersensitivity (cockayne syndrome, ataxia telangiectasia, and fanconi anemia) with strains derived from healthy donors, the fibroblast micronucleus assay has been established as a reproducible measure of the genotypic variation in spontaneous or mitomycin c (mmc)-induced chromosomal instability. the patient strains that were moderately or exquisitely sensitive to mmc, whereas the mildly se ...19883133207
shigella dysenteriae type 1 in tourists to cancun, mexico. 19883135475
revision of the grand mal epilepsy concept. 20113135582
symmetrical partial lateral 'cryptophthalmos'. a new concept of its embryological pathogenesis.a unique case of bilateral, partial cryptophthalmos is described, with no associated systemic anomalies. there were symmetrical, well-developed palpebral apertures medially with small conjunctival sacs, and symmetrical hemicryptophthalmos laterally. a faint groove extended temporally over the fused lids on both sides. there was a distinct plane of cleavage laterally between the disorganized microphthalmic globes and overlying tissues. the surgical observations are detailed.20113136414
further serological investigations in humans and domestic animals on the cape verde islands (q-fever, brucellosis, listeriosis, shigellosis, campylobacteriosis, yersiniosis, toxoplasmosis and chlamydia of plt-group).439 sera of domestic animals and various number (150-500) of human sera of the cape verde islands were examined for antibodies against coxiella burnetti, brucella abortus, b.melitensis, listeria monocytogenes, shigella dysenteriae, s.flexneri, s. boydii, s.sonnei, campylobacter jejuni, c.fetus ssp. intestinalis, yersinia enterocolitica, toxoplasma gondii and chlamydia of the plt-group. it could be shown, that on the cape verde islands there is to be counted with numerous zoonoses due to various ...19883139491
[methohexital/alfentanil-thiopental/alfentanil for total intravenous anesthesia for direct laryngoscopy with 100% o2 jet ventilation].for the direct laryngoscopy and microscopic examination of the larynx with exploratory excision and pulpectomy using low frequency jet-ventilation with 100% oxygen we used total intravenous anaesthesia with a strong acting opioid and a barbiturate. because the achievement of sufficient reflexes and a high degree of vigilance postoperatively are to be aimed, methohexitone (m) and thiopentone (t) were investigated in the regard of the suppression of vigilance in the postoperative period. 40 patien ...20113140687
effects of dietary-fish-oil feeding on muscle growth and damage in the rat.1. giving diets containing 100 g fully-refined, non-hydrogenated fish oil/kg to rats caused substantial modification of skeletal-muscle-membrane fatty acid composition compared with control animals fed on an equivalent diet containing 100 g maize oil/kg. 2. total muscle arachidonic acid (20:4 omega 6) was reduced from 138 (sd 25) mg/g total fatty acids to 15 (sd 2) mg/g and phospholipid arachidonic acid content showed equivalent changes. 3. reduction in muscle arachidonic acid content had no inf ...19883143398
anatomic basis for the construction of a musculotendinous flap derived from the pectoralis major muscle.the vascularization, innervation and termination of the clavicular portion of the pectoralis major muscle were studied by dissection of 7 adult subjects and 2 fetuses. the vascular and nervous autonomy of the clavicular portion was confirmed. blood-supply was effected by 2 arteries and innervation by an independent nerve. the exact distribution of the fibers composing the pectoralis major and their complex insertion are described. it is concluded that the clavicular portion can be employed as an ...20113145568
[improvement in cardiovascular autonomic dysfunction of a patient with opca with l-threo-3,4-dihydroxyphenylserine]. 20113147311
new aspects in the pharmacology of kindling implications for mechanism of of action in kindling.kindling is a long-lasting, transsynaptic, pathway-specific plastic change in brain function. it has been proposed as a model of neural plasticity, learning and memory, as well as a model of epilepsy. to elucidate the action of substances characterized by their ability to improve learning and memory and to have an activatory, protective and function restoring effect on nerve cells in distress, the effects of nootropic drugs and of antioxidative acting substances on the development of kindling an ...19873147457
using computers to take patient histories. 20113147730
interaction of horse-spleen ferritin with aluminium citrate.horse-spleen ferritin was found to bind al systematically following gel filtration in buffered al citrate 30 microm, and up to molar ratio 98 when incubated at 37 degrees c with al citrate, buffered to ph 7.4. pre-incubation with 3 concentrations of neutral sodium phosphate (0.1, 1.0, 10.0 mm) had no significant effect on binding. apotransferrin interaction with the al-ferritin complex to release fe but not al. protein-digestion and edta washing procedures showed that the al was firmly bound to ...19883147825
purification and some properties of shiga-like toxin from escherichia coli o157:h7 that is immunologically identical to shiga toxin.a cytotoxin to vero cells (shiga-like toxin), which was neutralized by antibody against purified shiga toxin produced by shigella dysenteriae 1, was purified from escherichia coli o157:h7, isolated from a patient with hemorrhagic colitis. the purification procedure consisted of ammonium sulfate fractionation, deae-cellulose column chromatography, chromatofocusing column chromatography and high performance liquid chromatography. about 200 micrograms of purified shiga-like toxin was obtained from ...19873148810
anti-idiotypic antibodies: a new generation of vaccines against infectious agents.anti-idiotypic antibodies have been suggested recently as candidates for potential vaccines against numerous infectious organisms. these antibody-based vaccines might represent a new generation of vaccines for inducing protective immunity in susceptible hosts.20103153167
microbial lipids betrayed by their fossils.novel families of microbial lipids have been betrayed by their molecular fossils. they comprise the very widespread and varied hopanoids, and 'orphan' lipids. membrane reinforcement appears to be universally achieved by these polyterpenoids; a hypothetical phylogenetic tree comprises the above, some postulated intermediates, bacterial carotenoids, cycloartenol, and finally cholesterol.20103153170
attractive propositions: microbial responses to chemical signals. 20103153179
five coping styles in families of children with cancer: a retrospective study in thirty families.this retrospective study concerned the coping behavior of 30 children with cancer and their families. fifteen families with children who were considered "cured" and 15 families with children who had died of their disease were questioned in partly structured interviews. in accordance with the coping model of lazarus, the following five different styles of coping by the family were identified: experiencing the disease as challenge, as probation, as misfortune, as fate, and as punishment. the evalu ...20103153243
continuous ecg monitoring of children with cancer receiving domperidone.domperidone is an effective antiemetic for children receiving cytotoxic therapy. there have been reports of cardiac arrest in older patients associated with domperidone. we carried out continuous ecg monitoring of 18 children receiving domperidone intravenously in a dose of 1 mg/kg body weight. no serious dysrhythmias were noted during 379 h of recording. single premature beats, transient sinus pauses, and nodal block were occasionally associated with vomiting and were no more common than would ...20103153247
recent advances and controversies in childhood renal osteodystrophy.renal osteodystrophy starts very early in chronic renal failure. although vitamin d levels are normal in patients with 70-80% function, the levels are not appropriate to the prevailing biochemical milieu. renal osteodystrophy may contribute to renal growth failure but a correlation between the degree of renal osteodystrophy and growth failure is not observed. catch-up growth cannot be obtained over a longer period of time with vitamin d. the main reason for osteomalacia is al intoxication. alumi ...20103153280
the biochemistry of endogenous organosulphur compounds.the role and metabolism of methionine and cysteine in mammals are described. an outline of the history of glutathione, of its function in maintaining the thiol status of the cell and of its protective action against oxidative stress, is given. the importance of glutathione reductase, glutathione peroxidases, glutathione-s-transferases in endogenous metabolism and of gamma-glutamyltranspeptidase is described. the relationship between cysteine and glutathione is considered together with the inter- ...20113155361
surgical management of palatally impacted cuspids. 20113155369
ct in low back pain syndrome.ct has become the imaging modality of choice for diagnosing the specific cause of low back pain syndrome. this article describes and illustrates those abnormalities commonly associated with low back pain: disk herniation, spinal stenoses, facet joint abnormalities, spondylosis, inflammatory conditions of the lumbar spine, and sacroiliitis.20113159990
the use of dura mater allograft in the surgical repair of large defects of the abdominal wall.the dura mater allograft is being used as an abdominal fascia substitute and major advantages are documented. it was used successfully in four patients at this institution, with a ten month follow-up period. its strength, durability, tissue tolerance, flexibility, ease of handling, nonallergenic property, availability and stability in the presence of infection make it a good graft to be used in the repair of large abdominal hernias. we are quite convinced that long term follow-up results will ve ...20103160130
the use of dura mater allograft in the surgical repair of large defects of the abdominal wall.the dura mater allograft is being used as an abdominal fascia substitute and major advantages are documented. it was used successfully in four patients at this institution, with a ten month follow-up period. its strength, durability, tissue tolerance, flexibility, ease of handling, nonallergenic property, availability and stability in the presence of infection make it a good graft to be used in the repair of large abdominal hernias. we are quite convinced that long term follow-up results will ve ...20103160130
surface charge of macrophages and their interaction with charged particles.the distribution and concentration of surface ionogenic groups on murine peritoneal macrophages and the responses of their plasmalemma to charged markers were investigated by electron microscopy. quantitation of the distribution of cationized ferritin (cf) as a marker for anionic groups on fixed cells revealed surface anions on invaginated parts of the plasmalemma to be fewer than those on flat or projecting segments. cationic groups on the surface membrane, however, could not be labeled with an ...20113164749
difficult denture birds--new sightings.a unique insight into characteristics, motivation, and behavior of problem complete denture patients is colorfully presented.20113165462
assessment of c-myc expression in individual leukemic cells.the expression of the proto-oncogene c-myc was studied at the protein level in cells obtained from patients with aml and cml. in florid aml and during the blastic phase of cml the majority of cells contain c-myc protein with the amount of protein differing widely among the cells of individual patients. in contrast, during complete remission in aml and during the chronic phase of cml cells containing c-myc protein are rare. several studies demonstrated a discordance in the amount of c-myc transcr ...20113165487
comparison of membrane fluidity and transferrin receptor expression as proliferation markers in lymphoproliferative disorders and in mitogen induced lymphoblasts.the correlation of two proliferation related events, membrane fluidization and transferrin receptor expression was studied in different lymphoid cells. with increasing grade of malignancy the membrane microviscosity decreased. moreover, resting lymphocytes differed significantly from chronic lymphocytic leukaemia cells in this parameter. [125i]fe2-transferrin binding increased with increasing proliferation capacity of cells. the membrane microviscosity of mitogen induced blasts was very similar ...20113165488
an unusual ventilator valve failure. 20113165607
third molar eruption in a 12-year-old girl. 20113165662
a correlation between regional acetylcholinesterase activity in rat brain and performance in a spatial task.the acquisition and retention of a water maze task was examined in 12 intact, young wistar rats. acetylcholinesterase activity in 43 discrete brain regions was then measured in the same rats by quantitative histochemistry. individual learning and retention indices were found to be significantly correlated with acetylcholinesterase (ache) levels in specific regions, e.g. cholinergic nuclei; the ventral pallidum and nucleus basalis; and in the dentate gyrus of the hippocampus. high levels of ache ...19883166718
bacteriophage degradation of the capsular polysaccharide of klebsiella k24 and determination of the position of the o-acetyl group. 19883167888
[dermatomycoses in children; a retrospective study 1977-1987]. 20113173519
control of diarrhoeal diseases.during its early years, who was primarily concerned with epidemic control, standardization and quality control of vaccines, and administration of the international sanitary regulations. among the acute enteric infections, cholera received the greatest attention because of its propensity for rapid epidemic spread. when the seventh pandemic of cholera began in 1961, who responded with a greatly expanded programme of activities which included cooperation with countries in training and control effor ...19883176516
an evaluation of serum ca 50 levels in cancer using a time-resolved fluoroimmunoassay.the ca 50 levels in serum samples from 440 patients were estimated using a dissociated enhanced lanthanide immunofluorimetric assay. the distribution was similar to ca 50-ria assays. raised levels (greater than 14 u/ml) were present in 95% pancreatic cancer, 68% hepatoma, 54% advanced colorectal cancer, 58% advanced breast cancer and 48% lung cancer. high values were observed in adenocarcinoma of the lung, and were related to tumour mass in small cell lung cancer. ca 50 is independent of cea. th ...20113179405
a study of the brain barrier in the ventral nerve cord of the american cockroach treated with hexane-acetone and ddt.the present study examines electrophysiological alterations in the blood brain barrier of the american cockroach when the solvent hexane-acetone is applied topically to the ventral nerve cord. rupture of the barrier was evaluated by perfusion with saline in which nacl was replaced with choline chloride at 28 degrees and 15 degrees c. the electrophysiological effects of an ethanol ddt suspension on the ventral nerve cord previously treated with hexane-acetone at 28 degrees c and 15 degrees c were ...20113179571
direct observation of molecular motility by light microscopy.we used video-fluorescence microscopy to directly observe the sliding movement of single fluorescently labeled actin filaments along myosin fixed on a glass surface. single actin filaments labeled with phalloidin-tetramethyl-rhodamine, which stabilizes the filament structure of actin, could be seen very clearly and continuously for at least 60 min in 02-free solution, and the sensitivity was high enough to see very short actin filaments less than 40 nm long that contained less than eight dye mol ...20113180250
actions of a phorbol ester on factors regulating contraction in rabbit mesenteric artery.the effects of 12-o-tetradecanoylphorbol-13-acetate (tpa) on isometric tension, unloaded shortening velocity determined using the slack test (vmax), and phosphorylation of myosin light chain (mlc20) were investigated in intact and skinned muscle tissues of the rabbit mesenteric artery. in intact muscles exposed to 128 mm k+, the vmax reached a maximum before the peak of the phasic component of contraction and reduced proportionally with changes in the amplitude of the subsequent tonic contractio ...19883180354
activity of glucosidase inhibitors against hiv infections. 19883182426
on being moral, ethical, and polite. 20113184949
[treatment of pollinosis in children by specific peroral hyposensitization]. 20113186412
[periarthritis of the shoulder. symptomology and classification]. 20113187101
[acute malignant histiocytosis in a patient with liebow's lymphomatoid granulomatosis (a case report)]. 20113188437
[endocrine function of the duodenum in patients with viral hepatitis a]. 20113188448
isolation of p multocida f-3,4 from a calf in the uk. 19883195018
[clinical and treatment characteristics of tertian malaria in viral hepatitis a]. 20113195076
miyakawa patellectomy.a miyakawa patellectomy was done in seventeen patients (twenty knees) for either osteoarthritis or chondromalacia of the patella, or both, secondary to malfunction of the extensor mechanism. patients who had had a patellar fracture were not included in the series. the miyakawa patellectomy realigns the extensor mechanism, with the proper tension, and centers the functional pull of the quadriceps tendon and patellar ligament. a superficial strip of the quadriceps tendon is pulled distally to fill ...20113198674
two mutant low-density-lipoprotein receptors in afrikaners slowly processed to surface forms exhibiting rapid degradation or functional heterogeneity.two distinct mutant low-density-lipoprotein receptors in south african afrikaners exhibit retarded posttranslational processing to mature forms. one mutation gives rise to cell-surface receptors that are subject to abnormally rapid degradation, whereas the other is associated with a functionally heterogeneous surface population degraded at a normal rate.20113202825
the magnesium-protoporphyrin ix (oxidative) cyclase system. studies on the mechanism and specificity of the reaction sequence.mg-protoporphyrin ix monomethyl ester cyclase activity was assayed in isolated developing cucumber (cucumis sativus l. var. beit alpha) chloroplasts [chereskin, wong & castelfranco (1982) plant physiol. 70, 987-993]. the presence of both 6- and 7-methyl esterase activities was detected, which permitted the use of diester porphyrins in a substrate-specificity study. it was found that: (1) the 6-methyl acrylate derivative of mg-protoporphyrin monomethyl ester was inactive as a substrate for cycliz ...20113202840
comparative studies on the accessibility and functional importance of tyrosine residues in cytochrome p-450 isozymes.cytochromes p-450 lm2 and p-450 lm4 from rabbit liver microsomes were chemically modified with tetranitromethane. nitration of two tyrosine residues of both isozymes inhibits the benzphetamine n-demethylase activity of p-450 lm2 as well as the p-nitrophenetole o-deethylase activity of p-450 lm4 by about 80%. for identification of the modified tyrosine residues the inactivated enzymes were digested with trypsin, and the labeled peptides were separated by hplc. sequencing of the 3-nitrotyrosine-co ...19883202847
[the young homeless of montreal: a longitudinal study].a transverse survey conducted in 142 young homeless (age: 18-30) shows that they mainly come from broken families where alcoholism, violence and mental illness hold an important place. regarding work, the majority of the surveyed homeless have not worked more than 24 months in all their life and have nearly continuously been on welfare; those who had jobs lost them much more because of their alcohol or drug use and their problems of interpersonal relationships than because of unemployment. on a ...20113203275
[the young homeless of montreal: a longitudinal study].a transverse survey conducted in 142 young homeless (age: 18-30) shows that they mainly come from broken families where alcoholism, violence and mental illness hold an important place. regarding work, the majority of the surveyed homeless have not worked more than 24 months in all their life and have nearly continuously been on welfare; those who had jobs lost them much more because of their alcohol or drug use and their problems of interpersonal relationships than because of unemployment. on a ...20113203275
pattern of glomerulonephritis in hong kong. 20113205602
[sudden death of a young adult and right ventricular cardiomyopathy]. 20093207241
conflict and the friendship relations of young children.the purpose of this investigation was to compare conflicts occurring between young children and their friends to those occurring between nonfriends. 53 children with a median age of 4 years, 3 months were observed and interviewed to determine who were mutual friends, unilateral associates, or neutral associates. 146 conflicts were also observed. conflicts between mutual friends, as compared to those occurring between neutral associates: (a) did not occur less frequently, differ in length, or dif ...20113208570
[remote afterloading transurethral radiotherapy of prostatic cancer]. 20113209920
detecting faking on the rorschach: computer versus expert clinical judgment.in a previous study of the ability of expert rorschach interpreters to detect faking that used true and malingered protocols, the experts faired very poorly. in this study, 50% of these same protocols were scored by the exner system and analyzed by exner's semantic computer interpretation program. the program indicated invalidity of protocols only on the basis of low r and designated the faked protocols high on psychotic descriptors, barely indicating psychosis for the true schizophrenic protoco ...20113210124
[a combination of an accessory large intestine and teratoid cysts of the intrapelvic tissue]. 20113210612
rapid preparation of samples for compositional sugar analysis of the "degraded polysaccharide" fraction of lipopolysaccharides from vibrio cholerae.a simple and rapid method was devised for direct isolation and fractionation of the "degraded polysaccharide" (dps) fraction of o-antigenic (or endotoxic) lipopolysaccharides (lps) directly from heat-killed vibrio cholerae (o1 and non-o1) cells without separating the lps. neither phenol-water extraction nor ultracentrifuge is needed in this method. v. cholerae nih 41 was used as standard. the cells (3-5 g wet weight) were heated in 5% acetic acid at 100 c for 1.5 hr. the acetic acid extract obta ...19883210996
[status quo in lipid diagnosis from the internal medicine viewpoint. discussion of the contribution of the same title by w. reuter in z. gesamte inn. med. 43 (1988) 71-74]. 20113213119
how patients know that nurses care about them. 20113216234
[surgery of cholesteatoma ears with good hearing]. 20113219644
lectin binding patterns of the human cornea. comparison of frozen and paraffin sections.twelve fitc-conjugated lectins were used to establish a reaction pattern with cellular and noncellular components in fresh-frozen and formalin-fixed paraffin sections of 11 normal human corneas. in frozen sections the epithelium demonstrated the most active lectin staining; keratocytes and endothelium stained to a lesser degree. of the noncellular components, the epithelial basement membrane and descemet's membrane of some of the tissues were stained most by phasolus vulgaris agglutinin (pha), p ...19883219860
[iridocyclectomy using a lamellar explorative technic. long-term studies].the question as to whether lamellar explorative iridocyclectomy always enables the spread of tumors of the iris base or ciliary body to be detected beyond doubt was verified in 11 patients who had been treated by this procedure more than four years previously. seven of the patients were available for reexamination. in two special cases it was found that this was not true. in the other patients neither histologic findings nor long-term follow-up revealed any tumor spread beyond the excision area, ...20113221658
defining measurement precision for effort dependent tests: the case of three neurobehavioural tests.for effort dependent tests, the estimation of measurement precision (reproducibility) is complicated by learning effects and submaximal efforts which inflate the variance of repeated trials. to illustrate an approach to the estimation problem, precision was evaluated for three neurobehavioural tests based on the responses of 76 boatbuilders tested on four separate test occasions within a one-week period. the average coefficient of variation (cv) for repeated trials within a test session was 6%, ...20113225104
modeling of therapeutic dialysis of cerebrospinal fluid by epidural cooling in spinal cord injuries.paraplegias of traumatic origin may be classified as primary or secondary. secondary traumatic paraplegia (stp) is believed to result from an autodestructive process. different authors have published results supporting or contradicting the therapeutic effects of durotomy alone or associated with exposed spinal cord and perfusion with a saline solution at normal or cold temperatures. it appears that although decompression and open dialysis might be beneficial, the surgical trauma over the injured ...20063225857
[introduction of personal computers to perinatology. clinical application. 9. in search of medical computers allowing smooth operation]. 20113230673
economic value of vitamin a and exhelm (morantel tartrate) in sheep in niger. 19883232646
teaching epidemiology in alfort veterinary school. 20113232672
the ascertainment sampling problem and estimation of genetic parameters when parental haplotypes are known.comparisons of bias and standard errors of genetic parameter estimates arising from various estimation procedures are made by using contrived genetic data in which parental haplotypes are known in addition to the haplotypes of affected sibs. these comparisons show that knowledge of parental haplotypes can reduce standard errors of genetic parameter estimates by between 10% and 45% as compared to estimates when parental information is not available. the added information does not appear to change ...20113232696
serum free thyroxine and free tri-iodothyronine in normal children.serum free thyroxine (ft4) and free tri-iodothyronine (ft3) were measured in 138 normal school children, adolescents and their younger siblings, whose ages ranged from 3 months to 18 years. mean ft4 concentration (16.8 pmol/l) was similar to the adult mean concentration of 17 pmol/l and all the values were within the adult reference range. at all ages the ft3 range was considerably higher than the adult reference range and the overall mean ft3 concentration (8.3 pmol/l) was at the upper limit of ...20113232955
characterization of regional left ventricular contraction by curvature difference analysis.a method which characterizes the contraction of the left ventricle (lv) by changes in the lv endocardial contour curvatures is presented. a normalized curvature difference function (ncdf) is defined by the difference between the (normalized) curvature functions of end diastolic (ed) and end systolic (es) contours. unlike wall-motion based procedures, ncdf is independent of any reference system and of the method used for ed-es shape alignment. normal and pathological diagnosis criteria were first ...20113233092
[central european study of the development of secondary sex characteristics in girls. i. axillary hair as the 4th secondary sex characteristic].as a part of the central european study a long-term study of the pubertal development of 687 hungarian girls was undertaken and the findings compared with those of a cross-sectional study of a group of girls from münster. in addition to assessment of the breast and pubic hair according to tanner's classification, the development of axillary hair was, for the first time, subdivided into five stages (a1 to a5). this pubertal feature was related to the characteristics already known and, because of ...20113234710
[pedodontics and nutrition. i. the pregnant woman]. 20113240696
[pedodontics and nutrition. i. the pregnant woman]. 20113240696
[first aid organization for cardiologic emergencies]. 20113244431
[pathophysiologic observations of facial neuralgia].the different etiology and pathogenesis of face-neuralgiae requires a spezific therapy of the respective illness. new aspects are formed in the last years in the so-called idiopathic neuralgia. she has good chances with the therapy through the jannetta-operation. the evident mechanical lesion by compression, the ephaptic genesis and the special pain-characterization with trigger-attacks not support the "idiopathic". this is called "ictal neuralgia". the paper attempts pathophysiological to expla ...20123244807
[deglutition disorders in cervical osteochondrosis]. 20123247103
aetiological spectrum of viral hepatitis in hospitalised adult patients in calcutta. 19883248987
oxygen-derived free radicals in cerulein-induced acute pancreatitis.conscious rats were treated with a supramaximal dose of 5.10(-6)g.kg-1.h-1 of cerulein for periods of 3 and 12 h. in both groups of animals typical features of acute oedematous pancreatitis were proved by biochemical and histologic examinations. the most important finding of our study was the decrease of superoxide dismutase (sod) activity in pancreatic tissue, accompanied by a slight increase of this scavenger enzyme in serum of rats stimulated with cerulein during 3 h. parallelly, evident elev ...19883249921
[new aspects and prospects of implants of the anterior chamber]. 19933250785
increased concentrations of tyrosine and phenylalanine in the cerebrospinal fluid as a possible reflection of related changes of the brain tissue in newborns with intra-uterine growth retardation.plasma and cerebrospinal fluid concentrations of tyrosine and phenylalanine were measured fluorometrically in human term neonates appropriate for gestational age and in neonates small for gestational age with severe intra-uterine growth retardation of type ii. the intra-uterine retarded newborns showed significant differences of both plasma and cerebrospinal fluid tyrosine levels as compared with the non-retarded newborns: the mean plasma and cerebrospinal fluid tyrosine were determined to be 2. ...19883254150
isolation and characterisation of a tandemly repeated dna sequence from the crucifer sisymbrium irio. 20123255663
laboratory evaluation of essential oil of mentha piperita linn. against trichophyton mentagrophytes. 19883255748
linkage relations for individual-site binding data. 20123256711
clinical adoptive chemoimmunotherapy with allogeneic alloactivated hla-haploidentical lymphocytes: controlled induction of graft-versus-host-reactions.a total of 13 cancer patients were treated with adoptive chemoimmunotherapy (acit) using alloactivated hla haploidentical lymphocytes. donor lymphocytes were activated in vitro using a pool of irradiated allogeneic lymphocytes (mlc-cells) and some further expanded by culturing in t-cell growth factor (tcgf-cells). the first 6 patients received i.v. cyclophosphamide (cpm) followed 24 h later by escalating doses of mlc-cells, then 7 days later they received an infusion of tcgf-cells. minimal toxic ...20113257904
inhibition of the proliferative response of human b lymphocytes to b cell growth factor by transforming growth factor-beta.the effects of transforming growth factor-beta (tgf-beta) on the proliferative response of human b cells to the low molecular weight b cell growth factor (bcgf) have been investigated in this study. it was found that tgf-beta, at picomolar concentrations, strongly inhibited the bcgf-induced proliferation of anti-mu chain or staphylococcus aureus cowan i-activated human b cells and also of a bcgf-dependent cell line derived from a human lymphocytic nodular lymphoma. this inhibitory effect was det ...19883257917
glucocorticosteroids induce dna fragmentation in human lymphoid leukemia cells.the present study was undertaken to investigate the potential role of glucocorticoid-induced dna damage in the lysis of human lymphoid leukemia cells by glucocorticoids. lymphoblasts were isolated from patients with acute lymphoblastic leukemia (all) or chronic myelogenous leukemia (cml) in blast crisis and cultured in vitro with or without dexamethasone. dna was then purified from the cells and analyzed by agarose gel electrophoresis. only high molecular weight (mol wt) dna was present in cells ...19883262387
effect of indomethacin on febrile response to recombinant human interleukin 1-alpha in rabbits.effects of indomethacin, a potent inhibitor of prostaglandin (pg) synthesis, on the fever induced by recombinant human interleukin 1-alpha (rhil 1-alpha) was studied in conscious rabbits. intracerebroventricularly administered rhil 1-alpha induced a dose-dependent increase in colonic temperature that was prominently suppressed by pretreatment with indomethacin given either intracerebroventricularly or subcutaneously. on the other hand, fever induced by intravenous administration of rhil 1-alpha ...19883263055
[haemophilus cellulitis--a contribution to the differential diagnosis of cheek swelling in childhood].the haemophilus influenzae cellulitis in infancy is a disease with special features in relation to early clinical recognition and treatment. we describe three such cases seen in our hospital with haemophilus influenzae as etiological agent. one patient died in consequence of a purulent meningitis recognized not in time and developing under antibiotic therapy not suitable for h. i. cellulitis. after review of the most important data from the literature suggestions were made for adequate diagnosti ...19883263609
a possible ligand of serum origin for the kidney autoantigen of heymann nephritis.earlier studies have localized the heymann nephritis (hn) autoantigen (gp330) in the coated pits of the plasma membrane and multivesicular bodies of the glomerular epithelial cell. because of these locations in the glomerular epithelial cells, it has been suggested that the hn ag may be a receptor. the aim of our study was to search for a ligand which can bind the hn autoantigen. normal rat serum was subjected to sds-page under reducing and non-reducing conditions followed by western analysis of ...19883264306
monoreactive high affinity and polyreactive low affinity rheumatoid factors are produced by cd5+ b cells from patients with rheumatoid arthritis.in patients with rheumatoid arthritis (ra), circulating cd5+ b lymphocytes, but not cd5- b lymphocytes, are increased in number and size, exist in an activated state, spontaneously proliferate, and secrete ig that binds to the fc fragment of igg. by constructing continuous mab-secreting cell lines from cd5+ b lymphocytes, the properties and dissociation constants (kd) of these antibodies were determined. two types of rheumatoid factors (rfs) with discrete reactivities were produced. the first ty ...20123264319
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