Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| [the etiological structure of shigellosis in the ussr in recent years]. | the characterization of etiological structure of shigella infection in the whole of the ussr, in individual union republics and at a number of other administrative territories of the ussr in recent years is presented. s. flexneri has been shown to prevail at the territories with unsatisfactory water supply of the population, and s. sonnei prevails at the territories with good water supply. at the former territories s. dysenteriae and s. boydii retain their etiological importance, while at the la ... | 1989 | 2698030 |
| [development of antibiotic resistance of type 1 shigella dysenteriae strains (shiga bacillus) isolated in tananarive on the east coast of madagascar]. | from november 1988 to march 1989, 804 malagasy children stools were studied and 37 shigella strains isolated. 5 shigella dysenteriae type 1 from malagasy east coast (mananjary), presented a multiply resistance to ampicillin, carbenicillin, streptomycin, chloramphenicol, tetracycline, sulphonamides and trimethoprim. this last resistance has recently appeared in this area. | 1989 | 2699224 |
| surrogate dentist: domestic medical guides and oral health care in the nineteenth century. | 2009 | 2700922 | |
| [dynamics of bile secretion under stressful conditions]. | 2009 | 2702266 | |
| penetrating eye injuries. | a review of all penetrating eye injuries treated at the manchester royal eye hospital over four years (1 january 1982-31 december 1985) was undertaken. a total of 202 penetrating eye injuries were seen of which 68 (34%) were in children under the age of 15 years. airgun, dart, and knife injuries accounted for 28 (41%) of the injuries. thirty seven patients (54%) achieved a good visual result (6/12 or better) and eight (12%) had enucleations. the period of inpatient treatment ranged from two to 1 ... | 2009 | 2705791 |
| the effect of n-3 polyunsaturated fatty acids on lipids, haemostasis, neutrophil and monocyte chemotaxis in insulin-dependent diabetes mellitus. | insulin-dependent diabetes mellitus (iddm) is associated with an increased risk of coronary artery disease (cad). there is some evidence that polyunsaturated fatty acids of the marine n-3 type (n-3 pufa's) may offer protection against cad. we have studied the effect of short-term dietary supplementation with n-3 pufas on lipids, haemostasis, neutrophil and monocyte chemotaxis in 10 patients with iddm. the patients were given 4 g daily of n-3 pufas (fish oil) for 6 weeks and were investigated bef ... | 2008 | 2706043 |
| thromboxane synthase activity and platelet function after furegrelate administration in man. | furegrelate sodium (u-63,557a), a pyridine-derivative thromboxane synthase inhibitor, was administered orally in single doses of 200 to 1600 mg to normal male subjects. furegrelate produced a dose-related inhibition of thromboxane synthesis for 8-12 hours when measured either ex vivo from platelet-rich plasma (prp) or in vivo from urine. in general, the extent of thromboxane synthesis inhibition was greater in prp than in urine. furegrelate significantly inhibited platelet aggregation, but the e ... | 1989 | 2708549 |
| a case of acute psychosis in temporal association with theophylline toxicity. | 2009 | 2708558 | |
| near-miss asphyxiation from a toy ball: a small parts failure. | the case report of a near-fatal asphyxiation of an 11-month-old child by a 26 mm (diameter) toy ball is presented. the lack of compliance with existing consumer product safety commission standards for small parts is discussed, and a recommendation is made regarding the coloring of ingestible objects. | 2009 | 2710666 |
| management of acute asthma. | 2009 | 2713796 | |
| pica: a clue to iron deficiency anemia. | 2009 | 2716310 | |
| immunoblotting analysis of the reaction of wildebeest, sheep and cattle sera with the structural antigens of alcelaphine herpesvirus-1 (malignant catarrhal fever virus). | malignant catarrhal fever (mcf) is a disease of cattle and some other ruminants caused by alcelaphine herpesvirus-1 (ahv-1), a virus of wildebeest. the disease also occurs in the absence of wildebeest and is then thought to be caused by a viral agent harboured by the sheep. the structural proteins of ahv-1 have been used as antigens for the immunoblotting analysis of sera from wildebeest, sheep and cattle infected by either ahv-1 or the "sheep-associated" form of the disease. wildebeest sera sho ... | 1989 | 2718352 |
| fast elisa for measuring serum antibody responses. | a method which speeds up the enzyme-linked immunosorbent assay (elisa) is described. the procedure uses a modified falcon fast assay screening system (becton dickinson labware, lincoln park, nj) and falcon round-bottom 96-well plates. antigen is adsorbed onto beads which extend from a lid and fit into 96-well plates. the beads are washed in a trough and reacted to antibody in the round-bottom plate. the labor required to wash the plates after coating with antigen, antibody or conjugate is thereb ... | 1989 | 2723439 |
| analytical determination of methylated histidine in proteins: actin methylation. | the methylation of histidine in actin from various muscle and nonmuscle sources has been studied by formation of phenylthiocarbamyl derivatives and subsequent reverse-phase high-pressure liquid chromatographic separation and analysis of actin hydrolyzates. all the actin species examined were found to contain 3-methylhistidine. this method has also been used in assays for the enzyme(s) responsible for methylation of rabbit skeletal muscle actin and to investigate the formation of other methylated ... | 1989 | 2729572 |
| determination of plasma homocysteine by high-performance liquid chromatography with fluorescence detection. | severe homocystinemia is frequently associated with vascular disease while the pathological consequences of moderate or slightly elevated plasma homocysteine are unknown. cobalamin and folate deficiencies may result in an elevation of plasma homocysteine. a sensitive and reproducible assay for total plasma homocysteine has been developed. the essential steps in the assay include (i) conversion of homocysteine disulfides to free homocysteine with borohydride reduction; (ii) conjugation of homocys ... | 2009 | 2729575 |
| in vitro and in vivo comparison of the abilities of purine and pyrimidine 2',3'-dideoxynucleosides to inhibit duck hepadnavirus. | four purine and two pyrimidine 2',3'-dideoxynucleosides were studied for their ability to inhibit duck hepadnavirus replication. the purine 2',3'-dideoxynucleosides were more potent antiviral agents than the pyrimidine 2',3'-dideoxynucleosides. the concentration for 50% inhibition of viral replication (ic50) was determined for each of the effective agents. two drugs with low ic50s, 2,6-diaminopurine 2',3'-dideoxyriboside and 2',3'-dideoxyadenosine, were chosen for in vivo studies. animals receiv ... | 1989 | 2729928 |
| large phosphate shifts with treatment for hyperglycemia. | although hypophosphatemia is known to commonly accompany therapy for hyperglycemia, it is not generally appreciated that severe life-threatening depletion of phosphate may occur. i followed up two patients who had precipitous drops during intravenous insulin therapy for diabetic ketoacidosis and hyperosmolar nonketotic state. the patient with diabetic ketoacidosis had a phosphate level nadir that equaled the lowest recorded phosphate level in a living human (0.03 mmol/l). because (1) serum phosp ... | 1989 | 2730261 |
| hemiplegia and amputation: rehabilitation in the dual disability. | about 10% of all elderly dysvascular amputees have had cerebrovascular accidents at some time. this is an often overlooked but important fact which significantly impacts the outcomes of their rehabilitation, especially where prosthetic ambulation is attempted. this study reviews the rehabilitation outcomes of 46 patients with the dual disability of hemiplegia and amputation. the mean age of the patients was 63 years (range 49 to 84). forty-one (89%) could participate in a trial of physical thera ... | 2002 | 2730308 |
| [papillary cystadenocarcinoma of the kidney. apropos of a case and review of the literature]. | 2002 | 2732502 | |
| late brain abscess years after severe cerebrocranial trauma with fronto-orbitobasal fracture. | an 8-year-old boy suffered severe craniocerebral trauma with left-sided fronto-orbitobasal fracture. the ct scan showed minor subdural air inclusions. the child recovered well and had no clinical signs of aftereffects. eight years after the accident, symptoms of intracranial pressure developed progressively with nuchal rigidity and elevated temperature. the ct showed an extensive left fronto-orbitobasal abscess. the intraoperative finding was a brain prolapse both into the frontal sinus and into ... | 2008 | 2736550 |
| late brain abscess years after severe cerebrocranial trauma with fronto-orbitobasal fracture. | an 8-year-old boy suffered severe craniocerebral trauma with left-sided fronto-orbitobasal fracture. the ct scan showed minor subdural air inclusions. the child recovered well and had no clinical signs of aftereffects. eight years after the accident, symptoms of intracranial pressure developed progressively with nuchal rigidity and elevated temperature. the ct showed an extensive left fronto-orbitobasal abscess. the intraoperative finding was a brain prolapse both into the frontal sinus and into ... | 2008 | 2736550 |
| [a three years follow-up study on the blood pressures of 6111 children in chengdu]. | this paper reports the results of a follow-up study in blood pressures of 6111 children for 3 years in chengdu city and the villages around. it was showed that the blood pressure for both the city and village children were elevated in overall with age. among the city children, the rate of bp-rising varied in different periods of childhood and that of girls above 13 was not significant. among village children, the rate of bp-rising for both male and female comparison to that of urban ones were si ... | 2009 | 2736619 |
| relationship between multiple drug-resistance & enterotoxin production by shigella species. | culture filtrates prepared with strains of shigella dysenteriae 1 and those of sh. flexneri and sh. sonnei, collected from different geographical locations in india caused accumulation of fluid in rabbit gut loops, indicating their capability to produce shiga and shiga-like toxins respectively. sh. boydii strains were noted for the first time to produce shiga-like toxins. the failure of production of fluid accumulation in rabbit gut by shigella strains that lacked the r-markers of the antibiotic ... | 1989 | 2737704 |
| panic attack-associated placental abruption: a case report. | a case of placental abruption is described in a nonmedicated pregnant woman with panic disorder who experienced panic symptoms and resultant hypertension. the authors suggest that sympathetic arousal associated with panic symptoms may have an adverse effect on the fetoplacental unit. the potential impact of untreated anxiety symptoms on fetal well-being must be considered when deciding whether pharmacotherapeutic intervention is appropriate for certain patients with anxiety disorders. | 2009 | 2738032 |
| fibrinogen nagoya, a replacement of glutamine-329 by arginine in the gamma-chain that impairs the polymerization of fibrin monomer. | structural studies on a hereditary abnormal fibrinogen, fibrinogen nagoya (takamatsu, j., ogata, k., kamiya, t., koie, k., takagi, t., & iwanaga, s. (1979) thromb. haemost. 42, 78), were performed to identify the abnormality responsible for the impaired polymerization of fibrin monomer. upon sodium dodecyl sulfate-polyacrylamide gel electrophoresis under reducing conditions, fibrinogen nagoya showed the presence of an extra protein band with an apparent molecular weight of 49,500 in addition to ... | 2009 | 2738036 |
| [use of the polymorphism of flanking dna probes with respect to the xq-27 region in a great fragile x pedigree]. | we analyzed the segregation between fragile site xq 27 and flanking polymorphic probes (52a, for factor 9, 4d-8, for factor 8, st14 and mn12) in a great xq-fra pedigree. on the basis of these data, the use of these probes is discussed in view of its value as a diagnostic tool. | 2008 | 2740689 |
| dislocated jaw. | 2009 | 2742562 | |
| synaptic cytoarchitecture of the cat septum pellucidum. | 1989 | 2747886 | |
| a ruptured cerebral aneurysm from choriocarcinomatous origin--a case report and a review. | a case of a ruptured metastatic aneurysm of choriocarcinoma is reported. the fourteen other cases of the literature are summarized. the pathological significance of this rare presentation of metastatic disease is discussed. the treatment of choice is defined as excision followed by chemotherapy and whole brain irradiation. the prognosis remains poor. | 2009 | 2747937 |
| who issues report on heavy metal and pah compounds from municipal incinerators. | 2009 | 2754439 | |
| perioral anesthesia disrupts maternal behavior during early lactation in long-evans rats. | the role of perioral somatosensory stimulation from pups in maternal behavior was investigated in lactating long-evans rats (rattus norvegicus) during early lactation by local anesthesia of the mystacial pads with lidocaine, which blocks conduction in the infraorbital nerve. it was concluded that (1) acute perioral anesthesia markedly inhibited pup retrieval when the subjects had no formal pretreatment retrieval experience. further, these dams displayed little tolerance to the lidocaine treatmen ... | 1989 | 2757582 |
| relationship between concentration and anticonvulsant effect of phenytoin against electroshock-induced seizures in rats: comparison of sampling sites for concentration determinations. | the purpose of this investigation was to determine the optimum sampling site for phenytoin concentration measurements in the context of pharmacodynamic studies of the anticonvulsant effect of phenytoin. determination of drug concentrations in the serum, serum water, brain, and cerebrospinal fluid (csf) of rats as a function of time after iv injection of a 6-mg/kg dose revealed a significant disequilibrium between brain and serum water for 15 min and between csf and serum water for 5 min after in ... | 1989 | 2760817 |
| [infection caused by paracoccidioides brasiliensis in people living in cocle and veraguas, republic of panamá]. | intradermal application of yeast phase paracoccidioidin antigen obtained by sonication and lysis from the fungus to 111 residents of veraguas province (68 men and 43 women) and 130 cocle province residents (57 men and 73 women) elicited a positive reaction in 9.01% (1/111) and 26.15% (34/30) of the veraguas and cocle residents respectively. positive reactions ranged between papules of 5 and 27 mm in diameter, the majority being between 11 and 20 mm. infection was more frequent in men (1:1.47 for ... | 1989 | 2762594 |
| car radiator burns: a report on 72 cases. | seventy-two cases of car radiator burns (crb) were treated in the burns unit, hamad medical corporation, doha, qatar, over a 6-year period (1982-87). all the patients were males and most were between 20 and 40 years old. chest wall, face and right upper limb were the commonest sites involved. most of the patients suffered from relatively minor scalds. the scenario of the accidents as well as the topography of the burned areas were characteristic to this particular type of injury. the exceptional ... | 2009 | 2765150 |
| convergence to stationary distributions in two-species stochastic competition models. | two sets of sufficient conditions are given for convergence to stationary distributions, for some general models of two species competing in a randomly varying environment. the models are nonlinear stochastic difference equations which define markov chains. one set of sufficient conditions involves strong continuity and phi-irreducibility of the transition probability for the chain. the second set has a much weaker irreducibility condition, but is only applicable to monotonic models. the results ... | 2009 | 2769087 |
| determination of estradiol 2- and 16-alpha-hydroxylase activities in mcf-7 human breast cancer cells in culture using radiometric analysis. | using a radiometric assay the effects of estradiol upon the activity of estradiol 2- and 16 alpha-hydroxylases in mcf-7 human breast cancer cells in culture were studied. after 5 days of treatment and 36 h of withdrawal, incubation in the presence of either 2- or 16 alpha-tritiated substrate was carried out. estradiol (10 nm) significantly increased 16 alpha-hydroxylase activity (21%, p less than 0.01), while no effects on 2-hydroxylase activity was observed. treatment for 6 weeks caused a major ... | 1989 | 2770303 |
| community care--up in the air? | 2009 | 2771747 | |
| [the importance of physiopathology in the management of peptic ulcer]. | 2009 | 2772478 | |
| twenty-year comparison of the human allograft and porcine xenograft. | this study compares a retrospective consecutive series of human allografts and concurrent porcine xenografts implanted over a 10-year interval. there were 571 allograft valves and 1,351 xenograft valves implanted in the aortic and mitral position with mean follow-up of 12.8 years for the allografts and 6.2 years for the xenografts. this study compares the incidence of structural deterioration over long-term follow-up. we found that there was no significant difference between four manufacturers o ... | 1989 | 2774760 |
| [glycogenosis type ii (pompe's disease) in a 6-month-old child]. | 2007 | 2780149 | |
| a strategy for high-volume sequencing of cosmid dnas: random and directed priming with a library of oligonucleotides. | direct sequencing of cosmid dnas using a library of oligonucleotide primers of length 8, 9, or 10 is proposed. the statistics of priming indicate that a primer library sufficient for determining the sequence of the entire human genome (100,000 cosmids) would be small enough to be assembled and managed. such a library would greatly reduce the cost and effort of high-volume sequencing: primers would be instantly available; the sequence of each cosmid dna could be determined from a single dna prepa ... | 1989 | 2780548 |
| neurochemical profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type a. | moclobemide belongs to a new generation of short-acting, reversible, monoamine oxidase (mao) inhibitors. in vitro (rat brain homogenates) moclobemide inhibits mao-a selectively with lower potency than many of the reference mao inhibitors. however, when measured ex vivo in the rat, the potency of moclobemide is similar to that of reference compounds. in vivo the drug induces a dose-dependent, short-lasting (8-16 hr) and preferential inhibition of mao-a in the brain and both mao-a and mao-b inhibi ... | 1989 | 2783611 |
| neurochemical profile of moclobemide, a short-acting and reversible inhibitor of monoamine oxidase type a. | moclobemide belongs to a new generation of short-acting, reversible, monoamine oxidase (mao) inhibitors. in vitro (rat brain homogenates) moclobemide inhibits mao-a selectively with lower potency than many of the reference mao inhibitors. however, when measured ex vivo in the rat, the potency of moclobemide is similar to that of reference compounds. in vivo the drug induces a dose-dependent, short-lasting (8-16 hr) and preferential inhibition of mao-a in the brain and both mao-a and mao-b inhibi ... | 1989 | 2783611 |
| co-localization of corticotropin-releasing factor- and enkephalin-like immunoreactivities in nerve cells of the rat hypothalamus and adjacent areas. | the co-localization of corticotropin-releasing factor (crf)- and enkephalin (enk)-like immunoreactivities in nerve cells of the rat hypothalamus and adjacent areas was investigated by the simultaneous application of immuno-beta-galactosidase staining and the peroxidase-antiperoxidase (pap) method to the same sections. crf-like immunoreactive cells were stained blue with immuno-beta-galactosidase staining and enk-like immunoreactive cells brown with the pap method. double-labeled cells with overl ... | 1989 | 2786446 |
| lymphokine-activated killer (lak) cells inhibit the clonogenic growth of human leukemic stem cells. | the effect of lymphokine-activated killer (lak) cells on the in vitro clonogenic capacity of acute myeloid leukemia (aml) blasts was investigated in a semisolid medium assay. the leukemic clonogenic capacity of 11 aml cases, selected on the basis of their ability to grow in vitro, was highly reduced following overnight preincubation with lak effectors. the degree of colony inhibition, which ranged between 66% and 98% (mean 83.8% +/- 11.4 sd), was quantitatively greater than by 51cr release, whic ... | 1989 | 2786477 |
| investigations of the potential for five beta-lactam antibiotics to elicit type ii hypersensitivity reactions in rats and monkeys. | immunologic reactions are occasionally elicited in patients by various beta-lactam antibiotics (e.g., penicillins and cephalosporins). a relatively rare reaction (type ii hypersensitivity) may involve antibody-mediated destruction of erythrocytes, leukocytes, and/or platelets. during the safety evaluation of several modified beta-lactam compounds (carbapenems), hemolytic anemia and/or neutropenia were observed in rhesus monkeys, and anemia, neutropenia, and thrombocytopenia in rats, after approx ... | 1989 | 2786479 |
| aging effects on secretory iga immune responses. | studies of cellular and humoral components of the secretory immune system indicated dramatic decreases in the siga response to t-dependent antigens (i.e. dnp-bgg) in aged rats. senescent rats (18-20 months old) showed comparable levels of siga anti-dnp antibody to adult animals after oral immunization with a t-independent antigen, dnp-ficoll. the salivary siga responses to both antigens were substantially decreased in weanling rats (21-35 days) versus the adult rats. significant anamnestic siga ... | 1989 | 2786502 |
| structure-activity study of the mechanism of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp)-induced neurotoxicity. ii. evaluation of the biological activity of the pyridinium metabolites formed from the monoamine oxidase-catalyzed oxidation of mptp analogs. | in the accompanying paper, several tetrahydropyridine analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) were screened for their abilities to be oxidized by monoamine oxidase (mao) to pyridiniums and to produce neurotoxicity in mice. we reported that most of the analogs were oxidized by mao to pyridiniums and some of the analogs were neurotoxic. we concluded that the capacity of a tetrahydropyridine mptp analog to be oxidized by mao to a pyridinium was a necessary, but not sufficient ... | 2009 | 2786565 |
| [intraoperative management of emergency coronary artery bypass grafting]. | intraoperative hemodynamics during emergency coronary artery bypass grafting (cabg) for acute evolving myocardial infarction (26 cases) were measured and compared with those during elective cabg (39 cases). before cardiopulmonary bypass period, it was strongly suggested that the cardiac function of emergency cases was worse than that of elective cases because of the following 5 factors; (1) hypotension, (2) tachycardia, (3) low stroke volume index, (4) pulmonary congestion and (5) metabolic acid ... | 2009 | 2786576 |
| [coagulation and fibrinolytic system of macrophages]. | 2009 | 2786578 | |
| regional pain syndrome. | 2009 | 2790410 | |
| [clinical significance of the quantification of obesity. the quetelet index and its use]. | the degree of obesity, ie. the quantity of excessive stored adipose tissue, affects substantially morbidity and mortality on cardiovascular, metabolic, and other diseases. while the quantity of an adipose tissue is practically impossible to determine, it is necessary to use the body weight, adjusted for the stature. the quetelet's index (body mass index, bmi) is the best one from height-weight indices. values of bmi define categories of normal weight, overweight, and obesity, which have differen ... | 2009 | 2790909 |
| intrahepatic lesions demonstrated to be hemangiomas after a ten-year lapse. | 2003 | 2791431 | |
| spinal chronic subdural haematoma in a 7-year old girl. | a case is reported of chronic encapsulated spinal subdural haematoma which developed in a 7-year-old girl after minor spinal trauma. surgical removal of the lesion was followed by complete recovery. | 2009 | 2792133 |
| detoxification of lithocholic acid. elucidation of the pathways of oxidative metabolism in rat liver microsomes. | the hydroxylation of lithocholic acid (3 alpha-hydroxy-5 beta-cholanoic acid) by adult male sprague-dawley rat liver microsomes supplemented with nadph was studied. metabolites were separated by a combination of thin-layer chromatography and high pressure liquid chromatography, both with and without prior methylation and acetylation of the samples. the resulting products were characterized by thin-layer, gas-liquid, and high pressure liquid chromatography by comparison with authentic bile acid s ... | 1989 | 2794781 |
| [osteolytic foci: cancer or not?]. | 2009 | 2797229 | |
| 31p-nmr study on intracellular energy transport in muscle. | 2009 | 2798486 | |
| 31p-nmr study on intracellular energy transport in muscle. | 2009 | 2798486 | |
| rapprochement and other crises. the specific and nonspecific in analytic reconstruction. | the historical development of preoedipality in evolving psychoanalytic theory is traced. particular reference is paid to the elaboration by mahler of the separation-individuation phase and the specific rapprochement conflict and crisis within it. in addition to the valuable contributions these discoveries have brought about, the tendency is noted for every new locus of interest to be obscured by excessive claims, and distorted by overuse and reductionism to explain complex and multidetermined be ... | 2002 | 2798609 |
| cognitive and social-emotional development of children in different preschool environments. | 62 english-speaking preschool children were divided into three groups, a montessori group (n = 21), a traditional preschool group (n = 21), and a homestaying group (n = 20) to compare their relative cognitive and social-emotional development. significant differences in favour of the school groups were found for vocabulary, language comprehension, ability to judge the correctness of figural stimuli, visual memory, and perceptual organization. no differences were found for social-emotional develop ... | 2009 | 2798666 |
| cognitive and social-emotional development of children in different preschool environments. | 62 english-speaking preschool children were divided into three groups, a montessori group (n = 21), a traditional preschool group (n = 21), and a homestaying group (n = 20) to compare their relative cognitive and social-emotional development. significant differences in favour of the school groups were found for vocabulary, language comprehension, ability to judge the correctness of figural stimuli, visual memory, and perceptual organization. no differences were found for social-emotional develop ... | 2009 | 2798666 |
| experimental studies on membrane permeability defects of drug-resistant bacteria. | multiply antibiotic-, lysozyme-and bacitracin-resistant, representative strains of staphylococci, escherichia coli, shigella dysenteriae and klebsiella pneumoniae were compared respectively with their parent cultures in respect of their membrane permeability as judged by fluorescence polarization spectroscopy, using a sensitive fluorescent probe. the cytoplasmic membrane of the drug-resistant mutants was found to be less fluid and permeable, compared to that from the sensitive wild types. the st ... | 1989 | 2807429 |
| purification of shiga toxin and shiga-like toxins i and ii by receptor analog affinity chromatography with immobilized p1 glycoprotein and production of cross-reactive monoclonal antibodies. | shiga toxin from shigella dysenteriae 60r was purified to homogeneity by a novel one-step receptor analog affinity chromatography method. the method was based on the binding affinity of shiga toxin for a specific disaccharide, gal alpha 1----4gal, which was also present in glycoproteins with p1 blood group seroreactivity produced in hydatid cysts from sheep infected with echinococcus granulosus. having shown that cyst fluid p1 glycoprotein bound shiga toxin on a solid phase, a p1 glycoprotein af ... | 1989 | 2807552 |
| carbohydrate structures of nonspecific cross-reacting antigen-2, a glycoprotein purified from meconium as an antigen cross-reacting with anticarcinoembryonic antigen antibody. occurrence of complex-type sugar chains with the gal beta 1----3glcnac beta 1----3gal beta 1----4glcnac beta 1----outer chains. | nonspecific cross-reacting antigen-2 (nca-2) is a glycoprotein purified from meconium as a closely correlated entity with carcinoembryonic antigen (cea). as in the case of cea, only asparagine-linked sugar chains are included in nca-2. in order to elucidate the structural characteristics of the sugar chains of nca-2, they were quantitatively released from the polypeptide backbone by hydrazinolysis and reduced with nab3h4 after n-acetylation. the radioactive oligosaccharides were fractionated by ... | 2010 | 2808357 |
| sex- and age-related changes in catecholamine metabolism and release of rat adrenal gland. | to examine the possible existence of changes in the adrenal catecholaminergic activity during aging, we analyzed the adrenal content of catecholamines (ca) and the activities of selected enzymes involved in their metabolism as well as the basal and the k+-stimulated release of these ca in incubated adrenal tissue of aged (greater than 22 months) and young (2 months) rats of both sexes. adrenal contents of norepinephrine (ne) and epinephrine (e) of male rats were unaltered in aging, although aged ... | 1989 | 2812194 |
| sex- and age-related changes in catecholamine metabolism and release of rat adrenal gland. | to examine the possible existence of changes in the adrenal catecholaminergic activity during aging, we analyzed the adrenal content of catecholamines (ca) and the activities of selected enzymes involved in their metabolism as well as the basal and the k+-stimulated release of these ca in incubated adrenal tissue of aged (greater than 22 months) and young (2 months) rats of both sexes. adrenal contents of norepinephrine (ne) and epinephrine (e) of male rats were unaltered in aging, although aged ... | 1989 | 2812194 |
| is a rise in [ca]1 responsible for rapid changes in neuronal excitability, ca currents, extracellular ions and ph0 induced by brief anoxia? | 2006 | 2816423 | |
| is a rise in [ca]1 responsible for rapid changes in neuronal excitability, ca currents, extracellular ions and ph0 induced by brief anoxia? | 2006 | 2816423 | |
| role of schwann cells in periaxonal ion regulation in the squid. | 2006 | 2816437 | |
| role of schwann cells in periaxonal ion regulation in the squid. | 2006 | 2816437 | |
| the renal phosphate transport defect in normal mice parabiosed to x-linked hypophosphatemic mice persists after parathyroidectomy. | the x-linked hypophosphatemic (hyp) mouse is a model for human x-linked hypophosphatemia. surgical joining of normal to hyp mice by parabiosis results in the normal mice developing low renal retention of phosphate and hypophosphatemia. these results suggest a humoral component to the renal defect. to test whether this component could be parathyroid hormone, surgical parathyroidectomy (ptx) or sham surgery was performed in mice 3 weeks after parabiotic union (n greater than 20 per group). after a ... | 1989 | 2816501 |
| [development of partner relations in very young mothers]. | a study was made on the development of partner relationships among adolescent mothers over a period of two years from the day of delivery onwards. from ascertained that there was still "definite marriage intention" or that the partners were interviewed at the maternity ward of the rostock county hospital and their data was compared with that of a control group of primiparae mothers (delivery age: 20-22y.). 73% of the partnerships of adolescent mothers with the child's father that existed at the ... | 2008 | 2816549 |
| [family dynamics of psychosocially disturbed adolescents]. | using a personality centered method psycho-socially disturbed adolescents aged between 17 and 22 years were treated by the intended dynamic group psychotherapy. an attempt was made to include the family in the care, which succeeded in 2/3 of the cases. the observations of the family dynamics are presented as follows: 1. a description of the dependence behaviour; 2. a phenomenologic description of disintegrating or rigid family structures; 3. the significance for therapeutic aims and prognosis is ... | 2008 | 2816551 |
| [characteristics of the course of the gestation period in patients with solitary kidney]. | clinical biochemical, bacteriological investigations and functional tests were performed in 37 pregnant females with a solitary kidney. the status of fetoplacental system was studied as well. the investigators noted such common complications of pregnancy as the aggravation of renal inflammation, a high rate of caesarean section and postnatal morbidity. it was concluded that in case of pyelonephritic affection a solitary kidney the pregnancy should be terminated. if the infection was absent and t ... | 2009 | 2817278 |
| the primary care role in occupational health nursing. | primary care is a valid, legal responsibility of the practicing occupational health nurse and accounts for a high percentage of the occupational health nurse's daily activities when considered on a local, national, and international level. historically, the varying definitions of primary care presented have led to confusion among practitioners who are attempting to categorize their services. the author attempts to express a workable interrelationship among these numerous terms including, "primar ... | 2009 | 2818762 |
| pharmacokinetics of adriamycin, adriamycinol, and antipyrine in patients with moderate tumor involvement of the liver. | the pharmacokinetics of adriamycin, its metabolite adriamycinol, and antipyrine were studied in 17 patients with moderate tumor involvement of the liver and compared to that of 19 tumor patients with normal liver function (preiss et al. 1985). the individual liver function parameters deviated from normal by a factor ranging from 2.5 to 12.2. the t1/2 alpha and t1/2 beta, the auc (corrected for body weight and dose) and the total body clearance (cl, corrected for body weight) of adriamycin did no ... | 2010 | 2824523 |
| redistribution of nuclear ribonucleoprotein antigens during herpes simplex virus infection. | infection of human epidermoid carcinoma no. 2 cells with herpes simplex virus type 1 (hsv-1) leads to a reorganization of antigens associated with both the small and heterogeneous nuclear ribonucleoprotein complexes (snrnp and hnrnp). the hnrnp core protein antigens remain associated with the host chromatin, which appears to collapse into internal aggregates and along the nuclear envelope. more striking is the formation of prominent clusters of snrnp antigens (both general and u1 snrnp specific) ... | 1987 | 2824525 |
| the versatility of hydroxyapatite blocks in maxillofacial surgery. | there is considerable interest at present in the potential role of calcium hydroxyapatite as a biomaterial for bone augmentation in oral and maxillofacial surgery. most of the published work has been on the particulate form, mainly in alveolar ridge procedures. however, hydroxyapatite is also available as solid or porous blocks. the blocks are more predictable in their use than are the particles, and are adaptable and versatile. this paper reviews the biological behaviour of the material and dis ... | 2010 | 2825758 |
| [reflections on 851 open heart operations at the institute of cardiology in abidjan]. | 2010 | 2826086 | |
| limb specific connections of the cat magnocellular red nucleus. | afferent and efferent connections of the limb specific divisions of the cat magnocellular red nucleus (rnm) were traced using the bidirectional transport of wheatgerm agglutinin-horseradish peroxidase complex (wga-hrp). injection sites within forelimb or hindlimb rnm regions were identified by microelectrode recording and confirmed by the position of labeled rubrospinal terminals. additional injections into structures that project to, or receive input from, rnm confirmed the somatotopic organiza ... | 1987 | 2826551 |
| cloning and sequencing of the genes for shiga toxin from shigella dysenteriae type 1. | the structural genes for shiga toxin, designated stx a and stx b, were cloned from shigella dysenteriae type 1 3818t, and a nucleotide sequence analysis was performed. both stx a and stx b were present on a single transcriptional unit, with stx a preceding stx b. the molecular weight calculated for the processed a subunit was 32,225, while the molecular weight of the processed b subunit was 7,691. comparison of the nucleotide sequences for shiga toxin and shiga-like toxin i (slt-i) from escheric ... | 1988 | 2830229 |
| transposon-induced alterations in the promoter region affect transcription of the chalcone synthase gene of antirrhinum majus. | four solid-colour revertants were isolated from the highly variegated niv-53::tam1 mutant, in which the transposable element tam1 is integrated in the promoter region of the chalcone synthase (chs) gene. dna sequence analysis revealed that in all four lines the tam1 element was deleted together with flanking nucleotides of the chs promoter. in one case the tata box of the chs gene was removed resulting in extremely low expression of the gene, and initiation of transcription occurring at a new po ... | 1988 | 2830468 |
| generation and recognition of leukotriene mediators of hypersensitivity and inflammation. | the potent mediators generated by the 5- and 15-lipoxygenation of arachidonic acid have diverse effects on smooth muscles, blood vessels, leukocytes, epithelial cells and glands, and sensory neurons, which suggest possible roles in the initiation and regulation of physiological and biochemical events. the responses to leukotrienes and related mediators are attributable to binding by stereospecific cellular receptors and consequent activation of biochemical transductional sequences analogous to t ... | 2010 | 2831014 |
| three distinct forms of type 2a protein phosphatase in human erythrocyte cytosol. | two type 2a protein phosphatases, phosphatases i (mr = 180,000) and iii (mr = 177,000), were purified to near homogeneity from human erythrocyte cytosol. phosphatase i was composed of alpha (34 kda), beta (63 kda), and delta (74 kda) subunits in a ratio of 1:1:1. phosphatase iii comprised alpha, beta, and gamma (53 kda) subunits in the same ratio. heparin-sepharose column chromatography converted most of phosphatase i and 20% of phosphatase iii into alpha 1 beta 1 which were indistinguishable fr ... | 1988 | 2831201 |
| nmr contrast agents for proton imaging. | 2010 | 2832350 | |
| two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance. | insulin receptor complementary dna has been cloned from an insulin-resistant patient with leprechaunism whose receptors exhibited multiple abnormalities in insulin binding. the patient is a compound heterozygote, having inherited two different mutant alleles of the insulin receptor gene. one allele contains a missense mutation encoding the substitution of glutamic acid for lysine at position 460 in the alpha subunit of the receptor. the second allele has a nonsense mutation causing premature cha ... | 1988 | 2834824 |
| two mutant alleles of the insulin receptor gene in a patient with extreme insulin resistance. | insulin receptor complementary dna has been cloned from an insulin-resistant patient with leprechaunism whose receptors exhibited multiple abnormalities in insulin binding. the patient is a compound heterozygote, having inherited two different mutant alleles of the insulin receptor gene. one allele contains a missense mutation encoding the substitution of glutamic acid for lysine at position 460 in the alpha subunit of the receptor. the second allele has a nonsense mutation causing premature cha ... | 1988 | 2834824 |
| [position of surveillance therapy in clinical stage i testicular non-seminoma]. | since the initiation of a 'surveillance' therapy the role of retroperitoneal lymph node dissection as standard treatment in the management of patients with clinical stage i nonseminomatous germ cell testicular tumor (nsgctt) continues to be debated. noninvasive staging techniques (ct scans, lymphography, ultrasound and serologic tumor markers) help to identify more accurately patients with distant metastases. 'surveillance' alone as a possible treatment modality following orchidectomy in selecte ... | 2010 | 2834854 |
| [means of improving the chemoradiotherapy of small cell cancer of the lung]. | the report deals with an analysis of the results of treatment of 84 patients suffering small cell lung cancer. four regimens of combination chemotherapy as well as radiation were used. complete plus partial regression rates ranged 18-81% (mean-42%) following chemotherapy and 73-87% after radiation treatment. platidiam-containing schemes proved most effective. prophylactic cranial irradiation was followed by increased survival. a correlation between extent of tumor and effectiveness of treatment ... | 2008 | 2839938 |
| [means of improving the chemoradiotherapy of small cell cancer of the lung]. | the report deals with an analysis of the results of treatment of 84 patients suffering small cell lung cancer. four regimens of combination chemotherapy as well as radiation were used. complete plus partial regression rates ranged 18-81% (mean-42%) following chemotherapy and 73-87% after radiation treatment. platidiam-containing schemes proved most effective. prophylactic cranial irradiation was followed by increased survival. a correlation between extent of tumor and effectiveness of treatment ... | 2008 | 2839938 |
| dna probes for shiga-like toxins i and ii and for toxin-converting bacteriophages. | a set of dna probes has been developed to study the genes for shiga-like toxins (slt) and the bacteriophage from which these toxin genes were isolated. under stringent conditions of hybridization (80 to 90% homology), these probes detect strains containing (i) slt i-related genes, (ii) slt ii-related genes, (iii) phage sequences from the slt i-converting phage h19a/933j, and (iv) phage sequences from the slt ii-converting phage 933w. strain characterization by hybridization with the toxin gene p ... | 1988 | 2842369 |
| [computerized tomography symptoms in 2 cases of primary linitis plastica of the rectum]. | 2009 | 2844723 | |
| study of plasmid screening amongst pathogenic bacteria isolated in nigeria. | clinical isolates of neisseria gonorrhoeae, campylobacter jejuni, escherichia coli, shigella dysenteriae, shigella boydii, yersinia spp. and salmonella spp. were screened for the presence of plasmids. approximately 80% of these strains harboured plasmids ranging in molecular weight from 1.0 to 45 x 10(6) daltons. | 1988 | 2845756 |
| pyrophosphate formation from acetyl phosphate and orthophosphate: evidence for heterogeneous catalysis. | the formation of [32p]pyrophosphate from acetyl phosphate and [32p]orthophosphate was studied under conditions in which phosphate-metal salts or acetyl phosphate-metal salts precipitate. in the absence of precipitates in purely aqueous media, the initial rate constant of transphosphorylation (kobs) was extremely small and the formation of pyrophosphate was detected only in the presence of calcium. in various combinations, conditions such as high ph, high concentrations of reactants, and the pres ... | 2010 | 2845863 |
| fatal asthma in a subject sensitized to toluene diisocyanate. | we report the case of a 43-yr-old car painter who died within 1 h of exposure to a polyurethane paint in the workplace. a diagnosis of asthma induced by toluene diisocyanate (tdi) had been established 6 yr before, when he underwent inhalation challenges with carbachol and with tdi. the subject had airway hyperresponsiveness to carbachol (pd20fev1 carbachol = 0.32 mg; normal value greater than 1.0 mg) and developed an early and long-lasting asthmatic reaction after exposure to tdi in the laborato ... | 2010 | 2849334 |
| transfer of pre-embryos donated and fertilized in vivo to recipients given a steroid replacement therapy. | this study describes eleven procedures of non-surgical recovery of preimplantation conceptuses from the uteri of eight fertile donor women and the transfer of the recovered pre-embryos into the uteri of infertile recipients with primary ovarian failure, or with hypothalamic--pituitary failure. conjugated oestrogens and progesterone were administered to recipients as replacement steroids during the first 20 weeks of pregnancy, in order to produce a secretory endometrium allowing nidation and deve ... | 2010 | 2851614 |
| effects of carbamylcholine on membrane potential and na-k pump activity of cultured rat skeletal myotubes. | 1. we measured changes in resting membrane potential (em) and na-k pump activity, assayed by ouabain-sensitive 86rb uptake, in response to carbamylcholine (cch) and its continued presence in single rat skeletal myotubes in culture. 2. cch caused immediate depolarization from control em (-80 to -85 mv) to near 0 followed by repolarization of varying degrees depending on the age of the culture and temperature of the recording medium; repolarization of em was most apparent by culture age 8-9 days i ... | 1988 | 2852060 |
| neuron-specific enolase in the diagnosis of small-cell lung cancer with pleural effusion: a negative report. | we measured the concentration of neuron-specific enolase (nse) and carcinoembryonic antigen (cea) in the serum and pleural fluid of 53 patients with pleural effusions, including seven patients with small-cell lung cancer (sclc). high levels (above 12.5 micrograms.l-1) of nse in pleural fluid were observed in five patients with sclc (sensitivity 71%). however, pleural fluid nse levels were also increased in five patients with other types of cancer and in four patients with non-malignant inflammat ... | 2010 | 2853080 |
| [effects of the long-acting analgesics 3-(beta-phenylethyl)-9 beta-methoxy-9 alpha-(m-hydroxyphenyl)-3-azabicycles [3,3,1]-nonane (p-7521) on opiate receptor binding in vitro]. | 1988 | 2855686 | |
| court of appeals rules dhss notice on family planning contrary to law. | in the december 1982 case of gillick v. west norfolk and wisbech aha, the british court of appeal acceded to mrs. victoria gillick's petition that no professional employed by the health authority be permitted to give contraceptive or abortion treatment to any of her children under the age of 16 without her prior knowledge and consent. the ruling held that a 1980 department of health and social security notice allowing treatment of minors without parental consent was contrary to law. the court ... | 1985 | 2856993 |