Publications

TitleAbstractYear
Filter
PMID(sorted descending)
Filter
[changes in toxicity of shigella shigae toxin in ontogenesis]. 195713461001
[changes in serological, antigenic and immunogenic characteristics, of virulence and toxicity in shigella dysenteriae resistant to an antibiotic grisemine]. 195713457259
[filtrable forms of salmonella typhosa, salmonella paratyphi, and shigella dysenteriae; method of production and regeneration modifying variability]. 195713457219
effect of chloramphenicol on lysogenization by temperate phage p1. 195713456369
[data on biology of shigella sonnei. ii. antigenic properties of total antigen of shigella sonnei]. 195713451192
[data on biology of shigella sonnei. i. biological effect of total shigella sonnei antigen]. 195713451191
[modification of antigenic composition of certain parenchvmatous organs in white mice infected with shigella dysenteriae and streptococcus]. 195713445950
[application of new quantitative precipitation method to immunochemical studies on shigella shigae]. 195713430328
bactericidal activity of rat leucocytic extracts. i. antibacterial spectrum and the subcellular localization of the bactericidal activity.all extract of polymorphonuclear leucocytes of the rat, prepared by means of ultrasonic vibration, was found to be bactericidal against m. aureus. the bactericidal activity was primarily confined to the mitochondrial fraction of the leucocytes. the rat leucocyte mitochondrial extract was bactericidal against both gram-positive (m. aureus, beta-streptococci, diplococcus pneumoniae, corynebacterium diphtheriae) and gram-negative (shigella dysenteriae, salmonella enteritidis, pasteurella pestis) ba ...195713428920
[food poisoning of dysenterial etiology]. 195713428056
[significance of hapten precipitation test in determination of the survival of dysentery bacilli in water]. 195713428044
[detection of shigella dysenteriae in artificially contaminated water with the aid of reaction of increase of phage titer]. 195713423769
[biological properties of flexner's and sonne's strains of shigella dysenteriae resistant to antibiotics]. 195713423767
[effect of functional modification in reactivity of the cerebral cortex to immunological activity]. 195613423759
[directed modification of properties of entero-typhoid bacteria in natural biocenosis in the intestines in rabbits]. 195613423740
[combined effect of antibiotics synthomycetin, biomycin and sanasine on shigella dysenteriae]. 195613418361
[synthomycetin-resistant strains of typical and atypical dysenterial bacilli and their properties]. 195613418360
[effect of tea on bacillus flexneri]. 195613410103
[shigella dysenteriae carriage in monkeys]. 195613410070
[duration and frequency of excretion of shigella dysenteriae in convalescents following dysentery]. 195613410061
[experimental principles in a new method of detection of shigella dysenteriae and salmonella typhosa with the aid of phages]. 195613410060
[use of antibiotics in control of carriage of shigella dysenteriae]. 195613408069
[pathogenesis and therapy of experimental intoxication with dysenterial toxin]. 195613408042
[25 strains of shigella dysenteriae 2 isolated in french colonies]. 195513403409
[antigenic relationship between escherichia coli and shigella dysenteriae]. 195613399798
[pharmacodynamics of certain bacterial toxins]. 195513395842
[survival and spreading of shigella dysenteriae in milk and in certain milk products]. 195513371682
[phenomenon of brown discoloration of culture medium by shigella dysenteriae]. 195613348105
[studies on variability of shigella dysenteriae following exposure to chloramphenicol]. 195613348034
[survival and shigella dysenteriae in water supply]. 195613344942
[chlorination of water infested with shigella dysenteriae]. 195613344934
the neurotoxin of shigella shigae; a comparative study of the effects produced in various laboratory animals. 195613342352
[concerning two new foci of dysentery caused by shigella dysenteriae 3]. 195613340480
[para-strains of shigella dysenteriae]. 195613325931
[epidemiological significance of atypical strains of shigella dysenteriae]. 195613325930
[intradermal allergic tests in rabbits sensitized with shigella dysenteriae]. 195613325928
[observations on the process of excretion of shigella dysenteriae in children in a closed institution]. 195613325926
[effect of cobalt on phagolysis shigella dysenteriae]. 195613325898
incorporation of phage dna on lysogenization of shigella dysenteriae. 195613315280
the neurotoxin of shigella shigae: morphological and functional lesions produced in the central nervous system of rabbits. 195513269656
observations on the intoxication produced in mice and rabbits by the neurotoxin of shigella shigae. 195513269655
[selection of strains of shigella dysenteriae for vaccines and simple method of their preservation]. 195513257785
[antigenic relationship of paracolon bacteria to shigella dysenteriae]. 195513253260
the neurotoxin of shigella shigae. 6. the relation between toxin and cytochrome production in the organism. 195513250114
the neurotoxin of shigella shigae. 5. the effect of iron and related metals on the growth, respiration and toxin production of shigella shigae and related organisms. 195513250113
the b antigens of shigella dysenteriae 2 and escherichia coli o group 112a, 112c. 195513233172
[effect of streptomycin on variability of shigella dysenteriae]. 195413213607
[certain properties of toxin of shigella shigae. v. modifications of parabiotic processes produced by shigella shigae toxin]. 195313209622
studies with shigella dysenteriae (shiga). v. factors involved in the preparation of toxoid. 195413201761
[preparation of anti-erythrocytic serum (anti-h) by immunization of goat with shigella dysenteriae]. 195413199106
[type-specific serums of shigella dysenteriae 2 (type schmitz)]. 195413179716
[seven cases of shigellosis caused by shigella dysenteriae in mexico city]. 195413177418
studies on lysogenesis. iii. superinfection of lysogenic shigella dysenteriae with temperate mutants of the carried phage. 195413174499
[utilization of soluble antigen of shigella dysenteriae for enteric immunization]. 195413170683
erythrocyte-modifying capacity of shigella dysenteriae (shiga) antigen and its polysaccharide component. 195413167120
[effect of streptomycin, synthomycetin and levomycetin on shigella dysenteriae]. 195313165056
[toxins of shigella dysenteriae]. 195413164993
a strain of shigella dysenteriae. i. requiring proline. 195413163001
studies in immunochemistry. 13. preparation and properties of the 'o' somatic antigen of shigella dysenteriae (shiga). 195413159883
[antigens and salmonella typhosa and of shigella dysenteriae]. 195413157256
studies on gastric mucin. i. in vivo and in vitro studies with shigella dysenteriae. 195313156977
[certain properties of shigella shigae toxin; effect of adenosinetriphosphoric acid on toxicity of shigella shigae toxin]. 195313141325
[effect of sulfonamides on inflammatory reaction causes by shigella dysenteriae]. 195413137500
studies on lysogenesis. ii. the effect of temperature on the lysogenization of shigella dysenteriae with phage p1. 195413129214
histological changes in the central nervous system produced by dysentery bacilli (shigella dysenteriae). ii. experiments in monkeys (macacus cyclopis). 195313103146
[studies on stain agglutination and electrophretic behavior of dysentery bacteria. i. shigella dysenteriae]. 195313091063
histological changes in the central nervous system produced by dysentery bacilli (shigella dysenteriae). i. experiments in rabbits. 195313090793
the neurotoxin of shigella shigae. iv. a semi-micro method for the flocculation assay of the toxin. 195313051534
the neurotoxin of shigella shigae. iii. the effect of iron on production of the toxin. 195313051533
the neurotoxin of shigella shigae. ii. examination of the toxin in the oil-turbine ultracentrifuge. 195313051532
the neurotoxin of shigella shigae. i. production, purification and properties of the toxin. 195313051531
studies with shigella dysenteriae (shiga). iv. immunological reactions in monkeys to the toxins in isolated intestinal pouches. 195313035094
the neurotoxin of shigella dysenteriae (shiga). 195212987385
morphological, host range, and genetic characterization of two coliphages.two coliphages, ar1 and lg1, were characterized based on their morphological, host range, and genetic properties. transmission electron microscopy showed that both phages belonged to the myoviridae; phage particles of lg1 were smaller than those of ar1 and had an isometric head 68 nm in diameter and a complex contractile tail 111 nm in length. transmission electron micrographs of ar1 showed phage particles consisting of an elongated isometric head of 103 by 74 nm and a complex contractile tail 1 ...200312957924
shigella dysenteriae serotype 1 in west africa: intervention strategy for an outbreak in sierra leone.in november 1999, a médecins sans frontières team based in the southeastern part of sierra leone reported an increased number of cases of bloody diarrhoea. shigella dysenteriae serotype 1 (sd1) was isolated in the early cases. a total of 4218 cases of dysentery were reported in kenema district from december, 1999, to march, 2000. the overall attack rate was 7.5%. the attack rate was higher among children younger than 5 years than in the rest of the population (11.2% vs 6.8%; relative risk=1.6; 9 ...200312957094
gasp phenotype: presence in enterobacteria and independence of sigmas in its acquisition.the appearance of growth advantage in stationary phase or gasp was originally detected in escherichia coli. the presence of this phenotype in other enterobacteria such as enterobacter cloacae, salmonella typhimurium, providencia stuartii and shigella dysenteriae is described in this work. e. cloacae gasp strains presented lower levels of rpos than the parental strain, although no mutation in the gene or its promoter was detected. this work offers evidence of gasp rpos-independent pathways as gas ...200312951242
human microvascular endothelial cells resist shiga toxins by ifn-gamma treatment in vitro.shiga toxins (stxs) produced by enterohaemorrhagic escherichia coli or shigella dysenteriae damage human endothelial cells predominantly in cooperation with pro-inflammatory cytokines, such as tnf-alpha. however, in this study, in vitro ifn-gamma pre-treatment resulted in human lung microvascular endothelial cells becoming over 10,000-fold less sensitive to stxs. in contrast, in their basal condition, they were extremely sensitive to stxs. interestingly, tnf-alpha addition to ifn-gamma reverted ...200312949184
thermodynamic analysis of the structural stability of the shiga toxin b-subunit.the conformational stability of shiga toxin b-subunit (stxb), a pentameric protein from shigella dysenteriae has been characterized by high sensitivity differential scanning calorimetry and circular dichroism spectroscopy under different solvent conditions. it is shown that the thermal folding/unfolding of stxb is a reversible process involving a highly cooperative transition between folded pentamer and unfolded monomers. the conformational stability of stxb is ph dependent and because of its pe ...200312899637
antimicrobial resistance of bacterial pathogens associated with diarrheal patients in indonesia.the antimicrobial susceptibility patterns for 2,812 bacterial pathogens isolated from diarrheal patients admitted to hospitals in several provinces in the cities of jakarta, padang, medan, denpasar, pontianak, makassar, and batam, indonesia were analyzed from 1995 to 2001 to determine their changing trends in response to eight antibiotics: ampicillin, trimethoprim-sulfamethoxazole, chloramphenicol, tetracycline, cephalothin, ceftriaxone, norfloxacin, and ciprofloxacin. vibrio cholerae o1 (37.1%) ...200312887025
protective efficacy of oral immunization with heat-killed shigella flexneri 2a in animal model: study of cross protection, immune response and antigenic recognition.oral immunization of rabbits with four doses of 10(11) heat-killed shigella flexneri 2a showed 100% protection against challenge with virulent s. flexneri 2a. after orally immunizing guinea pigs with four doses of heat-killed s. flexneri 2a 100% protection could be shown against ocular challenge with the same virulent s. flexneri 2a strain but this conferred no protection against challenge with shigella dysenteriae type 1. in enzyme-linked immunosorbent assay (elisa) and immunoblot experiments b ...200312798648
emergence of multidrug-resistant shigella dysenteriae type 1 causing sporadic outbreak in and around kolkata, india. 200312751679
aetiology of shigellosis in northern pakistan.people of northern pakistan face health hazards because of poor sanitation practices. bacterial gastrointestinal infections are very common, and sometimes outbreaks occur. the present study was aimed at evaluating and analyzing infestation of shigella spp. in patients with suspected gastroenteritis and ascertaining the status of antibiotic therapy. five hundred and eighty-five faecal samples of patients with suspected gastroenteritis, referred to the district headquarter hospital gilgit, were in ...200312751672
antibacterial efficacy of rumex nepalensis spreng. roots.the antibacterial property of rumex nepalensis spreng. was evaluated against some strains of bacteria. the methanol extract of the roots (tested at 200-1000 micro g/disc) showed significant concentration-dependent antibacterial activity.200312748999
subunit interaction of monomeric alanine racemases from four shigella species in catalytic reaction.bacterial alanine racemases are classified into two types of subunit structure (monomer and homodimer). to clarify the catalytic unit of monomeric alanine racemases, we examined the apparent molecular mass of the monomeric alanine racemases from shigella dysenteriae, shigella boydii, shigella flexneri, and shigella sonnei by gel filtration in the presence of the substrate and inhibitor. the enzymes were eluted on gel filtration as a monomer of about 39,000 da at low protein concentration and in ...200312725937
[effect of irradiation on the shelf-life of aquatic products].the effect of irradiation at doses of 0-10 kgy on the shelf-life of aquatic products was determined. the results showed that irradiation could not prolong the shelf-life of aquatic products kept at 25 degrees c. while the aquatic products were kept at refrigerator (4 degrees c), the irradiation could prolong the shelf-life and effectively reduce the total aerobic plate count. irradiation could effectively reduce the number of coliform to less than 300/kg and eliminate shigella shigae, salmonella ...200012725095
bidirectional concentration-dependent effects of tumor necrosis factor alpha in shigella dysenteriae-related seizures.we have previously demonstrated that pretreatment of mice with shigella dysenteriae sonicate enhanced their susceptibility to pentylenetetrazole-induced seizures and that tumor necrosis factor alpha (tnf-alpha) was proconvulsive in this respect. the present study shows that tnf-alpha, at high concentrations, may also exert a suppressive effect on shigella-mediated seizures. this implies that high levels of tnf-alpha may play a protective role in neurologic complications of s. dysenteriae infecti ...200312654859
synthesis of the pentasaccharide related to the repeating unit of the antigen from shigella dysenteriae type 4 in the form of its methyl ester 2-(trimethylsilyl)ethyl glycoside.starting from d-mannose, d-glucose and l-fucose, the pentasaccharide derivative methyl 2,3,4-tri-o-benzyl-alpha-l-fucopyranosyl-(1-->3)-2-o-acetyl-4,6-o-benzylidene-alpha-d-mannopyranosyl-(1-->3)-2-o-acetyl-6-o-benzyl-4-o-(2,3,4-tri-o-benzyl-alpha-l-fucopyranosyl)-alpha-d-mannopyranosyl-(1-->4)-[2-(trimethylsilyl)ethyl 2,3-di-o-benzyl-beta-d-glucopyranosid]uronate was synthesized. this compound with two alpha-mannopyranosyl units was transformed, via walden inversion and subsequent deprotection, ...200312644371
multidrug-resistant shigella dysenteriae type 1: forerunners of a new epidemic strain in eastern india? 200312643845
stx1c is the most common shiga toxin 1 subtype among shiga toxin-producing escherichia coli isolates from sheep but not among isolates from cattle.unlike shiga toxin 2 (stx(2)) genes, most nucleotide sequences of shiga toxin 1 (stx(1)) genes from shiga toxin-producing escherichia coli (stec), shigella dysenteriae, and several bacteriophages (h19b, 933j, and h30) are highly conserved. consequently, there has been little incentive to investigate variants of stx(1) among stec isolates derived from human or animal sources. however stx(1ox3), originally identified in an ox3:h8 isolate from a healthy sheep in germany, differs from other stx(1) s ...200312624011
shigella dysenteriae type 1 with reduced susceptibility to fluoroquinolones. 200312620764
histopathological study of rabbit intestinal mucosa infected with a hybrid strain of shigella dysenteriae 1 carrying lps biosynthesis genes of salmonella enterica serovar typhimurium.the rfb gene cluster and the rfc gene of salmonella enterica were introduced earlier into an invasive shigella dysenteriae 1 strain by triparental cross. antiserum was raised in rabbit against lipopolysaccharide isolated from the hybrid strain. both the hybrid and the invasive s. dysenteriae 1 strain were found to have a titer of 1:2560 while for s. enterica, it was 1:640. ligated ileal loops were prepared in rabbit, which were inoculated with 10(8) cfu ml(-1) each of the hybrid strain, and inva ...200312620623
antimicrobial potentiality of a phenothiazine group of antipsychotic drug-prochlorperazine.the antipsychotic drug, prochlorperazine (pcp), was tested for its antimicrobial efficacy against 103 strains belonging to both gram positive and gram negative bacteria. the drug was found to possess maximum activity against staphylococcus aureus, vibrio cholerae and shigella spp. pcp was moderately active against e. coli but most of the strains belonging to bacillus spp, klebsiella spp, salmonella spp and lactobacillus spp were found to be resistant to this drug. the drug was tested for its mod ...200212597553
surveillance of bacterial pathogens of diarrhea disease in indonesia.emerging or reemerging infections due to bacterial disease may be a local, regional or global problem. bacterial acute gastroenteritis is a potential cause of substantial morbidity in travelers and deployed u.s. military personnel. a surveillance study was conducted over a two-year period in indonesia among 6760 patients with debilitating diarrheal diseases. of the 6,760 patients, 587 (9%) of the patient stools were positive for bacteria. the proportions of bacteria isolated from the 587 patient ...200212493168
multicenter, randomized, double blind clinical trial of short course versus standard course oral ciprofloxacin for shigella dysenteriae type 1 dysentery in children.shigella dysenteriae type 1 (sd1) dysentery is associated with serious morbidity and mortality. treatment is either costly or complicated by the emergence of bacterial resistance. this study compared the efficacy and safety of short course (3 days) and standard course (5 days) oral ciprofloxacin in children with sd1 dysentery.200212488664
conformation of the branched o-specific polysaccharide of shigella dysenteriae type 2: molecular mechanics calculations show a compact helical structure exposing an epitope which potentially mimics galabiose.conformational analyses of the branched repeating unit of the o-antigenic polysaccharide of shigella dysenteriae type 2 have been performed with molecular mechanics mm3. a filtered systematic search on the trisaccharide alpha-d-galnac-(1-->3)-[alpha-d-glcnac-(1-->4)]-alpha-d-galnac forming the branch, shows essentially a single favored conformation. also, the downstream alpha-d-galnac-(1-->4)-alpha-d-glc linkage is sterically constrained. the alpha-d-glc-(1-->4)-beta-d-gal moiety, however, forms ...200212423964
identification of shiga toxin-producing bacteria by a new immuno-capture toxin gene pcr.infections with bacteria producing shiga toxin are responsible for widespread disease and for the death of a large number of people. in the present study, we have developed a rapid method of high specificity for the detection of shigella dysenteriae by combining immuno-capture of the bacteria and polymerase chain reaction (pcr) amplification of their toxin gene. we compared the sensitivity of our new method, referred to as immuno-capture toxin gene pcr (itgpcr), with a conventional tgpcr (ctgpcr ...200212423749
endotoxins of enteric pathogens are chemotactic factors for human neutrophils.early activation of human peripheral blood polymorphonuclear neutrophils is characterized by their morphological changes from spherical to polarized shapes. the endotoxins from enteric pathogens (s. dysenteriae type 1, v. cholerae inaba 569b, s. typhimurium, and k. pneumoniae) were assessed by their ability to induce morphological polarization of the neutrophils as measures of early activation. phagocytic activity, adhesion, chemokinetic locomotion, and nitroblue tetrazolium (nbt) dye-reduction ...200212359090
dysentery: an overview. still problems to resolve.this article reviews the global situation with regard to bacillary dysentery, with particular emphasis on findings from the recent epidemic in west bengal. infection is by the fecal-oral route and generally spread by person-to-person transmission. serious epidemics caused by the multiple-drug-resistant shigella shigae have occurred recently in bangladesh, somalia, south india, burma, sri lanka, nepal, bhutan, rwanda, and zaire. in each situation, dysentery attacked over 10% of the population ...198612341664
shigella dysenteriae type 1 in zimbabwe.shigella dysenteriae type 1 (sd1) is an unusually virulent enteric pathogen which causes endemic or epidemic dysentery with high death rates. sd1 has been responsible for large-scale regional outbreaks of dysentery in africa, central america, and south asia. shigella dysentery epidemics have been reported in africa since the 1800s and overall, more than 250 million people in the african region are at risk and subject to a case fatality rate of possibly 1-10%. in zimbabwe, the 1994 national in ...199712292400
cholera epidemic among rwandan refugees: experience of icddr,b in goma, zaire.in july 1994, one of the worst cholera epidemics broke out among the nearly a million rwandan refugees in goma, eastern zaire. the united nations high commission for refugees estimated that nearly 12,000 people died during the epidemic. the international centre for diarrhoeal disease research, bangladesh (icddr,b) sent an eight-member medical team to goma headed by dr ak siddique, a senior scientist of the center and head of the epidemic control preparedness program, dacca, bangladesh. during th ...199412288419
Displaying items 801 - 900 of 4425