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immune response and the b blood group locus in chickens.chickens of three blood group genotypes, b1b1, b1b2 and b1b19, were compared in their ability to produce antibodies. the b locus is the major histocompatibility locus in this species. homozygous b1 pullets had significantly higher adult mortality than did the b1 heterozygotes. in two separate experiments the b1b1 females produced significantly fewer antibodies to salmonella pullorum than did the b1 heterozygotes. also the b1b1 pullets responded with lower antibody titers following immunization w ...1975172405
the bursal origin of an immunocompetent cell for antibody formation in the chicken.surgically bursectomized and irradiated chickens were given bursal, splenic, bone marrow or thymic cells taken from syngeneic donors, together with killed brucella abortus and salmonella pullorum. blood samples were taken from those chickens 7 days later, and the serum agglutinin titres were determined. the cells of any lymphoid organ taken from 28-day-old chickens were more effective in restoring antibody response than those from 18-day-old ones. the restorative capacities of the bursa and sple ...1975808466
[dynamics of the agglutinin titer in chicks with pullorum disease-fowl typhoid]. 19751114666
social interactions and antibody titres in young male chickens (gallus domesticus).the influence of social interactions on established antibody titres to a salmonella pullorum antigen was determined in several athens randombred families. in two experiments, a large-bodied, aggresive family and a small-bodied, relatively non-aggressive family were placed in three social environments: (1) four-bird control groups with no changes in membership once formed; (2) three-bird resident groups to which a new fourth bird was introduced daily; (3) the single bird that had been moved to ...19751172392
diverse effects of bursectomy on humoral immune responses in the chicken.chickens bursectomized hormonally or surgically at various ages in embryonic to postembryonic lives were immunized with a mixture of antigens, and the antibodies produced titrated. immune responses to salmonella pullorum (sp), brucella abortus (ba). staphylococcus aureus (staph) and ovalbumin (oa) were more markedly suppressed by the bursal deprivation than those to heterogenous erythrocytes, viruses and such bacteria as pasteurella multocida (pm) and escherichia coli b. the immune response to b ...19751187514
[age-related susceptibility of chickens to salmonella pullorum infection]. 19751216537
[the antibiotic sensitivity patterns of salmonella pullorum and salmonella gallinarum in in vitro studies].the antibiotic sensitivity patterns of 100 strains of s. pullorum and 24 strains of s. gallinarum against 19 antibiotics and 3 antibiotic mixtures were determined by the broth dilution method. the strains studied were isolated from enzootic outbreaks of pullorum disease and fowl typhoid. it was found that all the strains were sensitive to ampicillin, streptomycin, neomycin, kanamycin, oxytetracycline, chloromycetin, gentamycin, signamycin, polzomycin, and neotarchocin. besides, s. pullorum was s ...197516296026
[hygienic standardization of octylic stabilizors pvc in water bodies]. 19751213373
liver disease, carbohydrate metabolism and diabetes. 19761445166
effects of early cyclophosphamide treatment on lymphoid organs and its immune response in ducks.cyclophosphamide treatment of newly hatched white pekin ducks significantly reduced the weight of their lymphoid organs and almost completely eliminated the formation of bursal lymphoid follicles at one week of age. there after the thymus and spleen of these ducks completely recovered in weight at 7 weeks of age. the bursa, however, retained its light weight and morphological defects, such as the absence of lymphoid follicles. the specific antibody producing-capability to salmonella pullorum was ...1976951372
[antibiotics and chemopreparations in poultry pullorum disease]. 1976960534
age-dependent resistance of chickens to salmonella in vitro: phagocytic and bactericidal activities of splenic phagocytes.the phagocytic and bactericidal activities to salmonella pullorum (strain 9-25) or salmonella senftenberg (strain 99d) were examined in chicken splenic phagocytes from 0-day-old to 2-month-old chickens. the phagocytic activity against s pullorum increased in splenic phagocytes from chickens older than 7 days, but significant changes in activity against s senftenberg were not observed during the experimental period. the bactericidal activity of splenic phagocytes against s senftenberg was higher ...1976962210
a simplified biochemical system to screen salmonella isolates from poultry for serotyping.the 24 most frequently isolated paratyphoids from poultry, along with salmonella gallinarum and salmonella pullorum, plus strains of arizona, citrobacter, edwardsiella, escherichia, klebsiella, prteus, pseudomonas, serratia and shigella were inoculated into triple sugar iron (tsi) and lysine iron (li) slants and into six fermentation broths which were numbered: 1 (dextrose), 2 (lactose), 3 (sucrose), 4 (mannitol), 5 (maltose), 6 (dulcitol). all the salmonella cultures (except s. pullorum) gave a ...1976995819
humoral immune responses characteristic of testosterone-propionate-treated chickens.white leghorn chickens treated with testosterone-propionate on the 3rd day of embryonation were immunized with a mixture of sheep red blood cells, brucella abortus and salmonella pullorum at various ages, and the resulting agglutinins were titrated. the production of igm antibody against sheep red blood cells was not affected significantly by testosterone-propionate. on the contrary, immune responses against the bacterial antigens were strongly suppressed by the same treatment. production of igg ...1976815175
the augmentation of antibody responses by preliminary intrabursal priming in the chicken.direct injection of antigen into bursal tissue of young chickens followed by subsequent intravenous immunization markedly stimulated agglutinin production against brucella abortus. in contrast, preliminary intravenous immunization did not produce stimulation. the promoting effect of intrabursal injection was antigen-specific. antigen injection into the bursa reduced the extent to which subsequent bursectomy suppresses the immune response. bursa cells from young chickens which had been injected w ...1976829231
[economic effectiveness of antibiotics in pullorum disease-fowl typhoid in poultry]. 1976139739
[immunosuppressive activity of several drugs and their effect on antibody formation in pullorum disease].furazolidon given alone or in combination with chloramphenicol, with spectinomycin, with gentamycin or with sodium arsenilate as well as chlorpyrazine, applied alone, suppress the clinical manifestation of pullorum disease in birds both in the experimental and in the spontaneous outbreak of the disease. these medicinal drugs lower the production of agglutinins in birds--mostly the combination furazolidon+chloramphenicol, followed by furazolidon+sodium arsenilate. the same combinations do not pro ...1977147557
age-dependent resistance of chicken of salmonella in vitro: antibacterial activity of lysed granule fraction of splenic adherent cells.lysed granule fraction was prepared from splenic adherent cells from 0-day-old to 2-month-old chickens and was examined antibacterial activity to salmonella pullorum and salmonella sentfenberg. the activity of lysed granule fraction from 2-month-old chickens was exhibited at ph 5.0 but not exhibited at ph 6.0 or 7.0 to both serotypes of salmonella. at ph 5.0, lysed granule fraction from 0-day-old chickens revealed little antibacterial activity to s. pullorum but the activity increased with incre ...197715389
[introduction of an additional h-agglutinating test antigen for the differentiation of specific positive reactions in pullorum disease-fowl typhoid in poultry experimentally infected with salmonella gallinarum-pullorum and salmonella enteritidis].explored were the possibilities to differentiate the specific positive reactions in case of pullorum disease in experimentally infected (salmonella gallinarum-pullorum and salmonella enteritidis) birds with the use of a typhoid test antigen and two h test antigens, obtained by the routinely employed method with formalin from salmonella enteritidis and salmonella adeoyo. it was demonstrated that the h-agglutinating antibodies persisted in the peripheral blood of the experimentally infected birds ...197775606
[immunogenicity in salmonella gallinarum-pullorum irradiated with gamma rays].studied with the imunogenicity of salmonella gallinarum-pullorum bacteria treated with 1, 10 and 20 mr gamma rays or killed with acetone. bacterial cultures were irradiated with a lmb-gamma m device, having a 137cs source, single doses being of a 3,252 r/min power biozzi's clearance test was employed to determine the changes in the immunogenic properties of the irradiated bacteria. the results obtained with both the clearance test and the protection test spoke of a considerable drop in the immun ...1977343353
[antibody dynamics in growing birds experimentally infected or naturally sick with white diarrhea].serologic studies were carried out with growing birds, aged 37-70 days, experimentally and spontaneously infected with salmonella gallinarum and salmonella pullorum, respectively. more positively reacting birds were found by means of the whole-blood agglutination reaction with typhoid-pullorum test than in the study of the same birds when aged 6-7 months. the investigation of birds when young is also advantageous in that there are no losses of eggs, it is more readily carried out, and the infect ...1977929972
secular trends of annual morbidities of animal infectious diseases.supposing two mathematical models, additive and multiplicative, the authors estimated the secular trends of annual morbidities (1949 approximately 1975) of twelve infectious diseases of domestic animals. for each diseases ten different trend curves were fitted. it was found that five regression equations, namely, those for bovine trichomoniasis, bovine tuberculosis, equine infectious anemia, pullorum disease in chickens, and foulbrood, gave the coefficient of determination of 97.9, 92.7, 91.0, 9 ...1977604789
[diagnostic value of serological methods and of the allergy method in studying pullorum disease-fowl typhoid in poultry].it was established that the positive allergy reaction was best expressed at the forty-eighth hour following the introduction of the allergen. the diagnostic value of the allergy reaction was not shown to surpass that of the serum agglutination reaction. it proved to be close to the value of the other serologic methods of examination (the whole-serum and whole-blood agglutination tests). the allergy method of investigation could be used as a tentative method, resp., reaction test for the detectio ...1977607558
[genetic polymorphism of poultry blood serum esterases in relation to resistance to bacterial infections].the experiments were carried out on white leghorn, white rock and cornish chickens during the 1974--1975 season. the aim of the investigation was to study polymorphism of blood esterases in chickens in relation to their resistance to salmonella pullorum and s. gallinarum. the data obtained indicate the following: 1) an additional, inheritant alyesterase fraction (a1) appears in blood serum of resistant chickens after their contamination with salmonella; 2) most chickens, which are resistant to s ...1977611042
the history of avian medicine in the u.s. ii. pullorum disease and fowl typhoid. 1977334148
inhibition by paromomycin of r-factor transfer of tetracycline resistance between escherichia coli and salmonella pullorum.in vitro assays showed that low concentrations (5--10 and 20 microgram/ml) of the antimicrobial paromomycin sulfate are able to block or diminish significantly the transfer of the tetracycline resistance r-factor between escherichia coli and salmonella pullorum. this observation is important because it offers the possibility of preventing the formation of tetracycline-resistant pathogens, a limiting factor of tetracycline use in both human and veterinary medicine.1978338888
the role of the thymus for maturation of transferred bursa cells into immunocompetent b cells in chickens treated with cyclophosphamide.chickens injected with cyclophosphamide and x-ray irradiated in the newly hatched period were immunized with a mixture of sheep red blood cells, brucella abortus and salmonella pullorum at 4, 5 and 6 weeks of age, and were examined for serum antibody titres, serum immunoglobulin concentration and bursal and splenic structures at 7 weeks of age. the neonatal treatments suppressed completely or almost completely antibody responses, immunoglobulin production and formation of bursal follicles and sp ...1978310807
[prevention of pullorum disease in chicks]. 1978695280
animal salmonellosis in peninsular malaysia. ii. annual and zoological distribution of salmonella serotypes over the 10-year period 1966-1975.a total of 860 salmonella isolations were made in peninsular malaysia from 15 animal species (domestic and wild), eggs, molluscs, flies, and animal feed. the isolations were distributed among 31 serotypes in eight groups. the most common serotype isolated was salmonella pullorum, followed by s. choleraesuis and s. infantis. s. typhimurium had the widest zoological distribution. the importance of controlling animal salmonellosis is emphasized.1978354419
[indirect hemagglutination reaction in pullorum disease-fowl typhoid]. 197880877
[origin of a mitogrenic factor for cultivated macrophages (imf: inflammatory mitogenic factor) found in exudates of non-specific acute inflammation].the mitogenic activity of inflammatory exudate obtained from irradiated rats is reduced. after transfer of bone marrow syngeneic cells into irradiated rats this mitogenic activity is further decreased, while after transfer of thymic cells it is increased. it is postulated that the mitogenic activity of inflammatory exudate could be related to thymic cells and that t lymphocytes may be involved in non specific-inflammatory reactions.1978100246
[calcium kinetics of myocardium in experimental hypercalcemia and isoproterenol lesions--ultrastructural and roentgen microanalytical findings]. 1978106573
[prevention of pullorum disease-fowl typhus in poultry]. 1979158252
[infectious bronchitis and pullorum disease in chickens]. 1979222043
[salmonella pullorum-infection in a laying flock of chickens (author's transl)]. 1979367748
prevalence of certain antibodies to selected disease-causing agents in wild turkeys in texas.in texas in 1976 and 1977, rio grande turkeys (meleagris gallopavo intermedia) from seven counties and eastern turkeys (m. g. silvestris) from one county were tested for antibodies to selected poultry pathogens. standardized serological tests disclosed reactors to salmonella pullorum (2.4%), s. typhimurium (2.3%), and mycoplasma gallisepticum (4.8%). there were no reactors to newcastle disease virus or chlamydia psittaci. prevalence of m. gallisepticum antibody in wild turkeys was significantly ...1979384989
cross-protection aginst salmonella enteritidis infection in mice. i. immunization trials.mice were immunized subcutaneously with live and killed vaccines, with and without complete adjuvant incorporating salmonella typhi-murium m206, salmonella gallinarum 9r, salmonella pullorum sp223 as well as homologous salmonella enteritidis se795. the animals were challenged 21 days post-vaccination with 100 ld50 of virulent s. enteritidis 5694 smr subcutaneously along with unvaccinated control mice. to assess the immunity against acute and chronic infections, the percentage of absolute survivo ...1979397731
cross-protection against salmonella enteritidis infection in mice.mice were immunized subcutaneously with live vaccines and live vaccines with complete adjuvant incorporating salmonella enteritidis se 795, salmonella typhi-murium m206, salmonella gallinarum 9r or salmonella pullorum sp223. they were challenged along with unvaccinated controls with 100 ld50 of virulent s. enteritidis 5694 smr subcutaneously on the 21st day post-vaccination. the humoral immune response was studied by assessing the sequential level of agglutinins, complete and incomplete somatic ...1979397732
cross-protection against salmonella enteritidis infection in mice. iii. delayed hypersensitivity reaction and clearance of the challenge organism.mice were immunized with live vaccines and with live vaccines with complete adjuvant incorporating salmonella enteritidis, salmonella typhi-murium, salmonella gallinarum or salmonella pullorum. on the 21st day after vacination, the hypersensitivity reactions elicited by the mice to extracts of the challenge organism (s. enteritidis 5694 smr) were assessed. the degree of delayed hypersensitivity reaction was compared with the level of protection induced by the vaccine. the role in protection of d ...1979397733
synaptogenesis in the cervical cord of the human embryo: sequence of synapse formation in a spinal reflex pathway.synaptogenesis in the cervical cord was studied by light and electron microscopy in human embryos ranging from four to seven weeks of ovulation age. the stage of embryonic development was estimated on the basis of external morphology of embryos and histology of the eye ball with reference to streeter's horizon. no synapses were found in the cervical cord of the embryo at streeter's horizon xiv (8 mm; estimated ovulation age, 28-30 days). a small number of axodendritic synapses appear in the moto ...1979422753
serological response of chickens to salmonella thompson and salmonella pullorum infections.chickens were experimentally infected with salmonella thompson (serogroup c, paratyphoid) and salmonella pullorum (serogroup d). five serological methods and one cultural method were used in detecting the infections. the microantiglobulin test was superior to all other methods for detection of paratyphoid (s. thompson) infection and was followed in efficacy by the microagglutination test, rapid serum plate test, cloacal swab culture, macroscopic tube agglutination test, and rapid whole-blood tes ...1979429534
observations on salmonella infections of birds.during the period 1961 to 1976, 29 species of salmonella other than salmonella pullorum were isolated from 180 accessions of birds examined at the animal research institute, yeerongpilly. these birds were submitted to the laboratory from flocks with disease or production problems. s. typhimurium was the most frequently isolated serotype being obtained from 63% of accessions. outbreaks of systemic salmonellosis occurred most frequently in young birds and although pathological changes were most co ...1979435204
[diagnostic value of the indirect hemagglutination reaction in pullorum disease-fowl typhoid]. 1979452403
restricted dietary protein in pregnant beef cows: ii. effect on the immune response.cows fed 0.37 kg crude protein per day for four months before calving showed no decrease in colostral igg, iga, or igm from cows fed a normal ration. similarly, no difference in serum immunoglobulin concentration was detected in their calves. cows in the low protein group developed significantly lower (p < 0.01) titers to salmonella pullorum antigen than did the normal group. the data show significant positive linear regressions of calf agglutination titer to s. pullorum on the dam's colostral t ...197916725433
the development of unusual b-cell functions in the testosterone-propionate-treated chicken.chickens were treated with 4 mg of testosterone propionate on the twelfth day of embryonic life. bursal remnants of testosterone-treated chickens were very small in size and had very few or no bursal follicles: the lymphoid tissue was replaced substantially by fibrosis. testosterone-treated chickens formed almost exclusively igm antibodies to sheep red blood cells and influenza virus, whereas no igm or igg response to brucella abortus or salmonella pullorum, and no igg response to sheep red bloo ...19806966602
[ampicillin and rivanol in pullorum disease-fowl typhoid in chicks]. 19806771914
performance of 3 successive generations of specified-pathogenfree chickens maintained as a closed flock.no antibodies against salmonella pullorum, mycoplasma gallisepticum, mycoplasma synoviae, haemophilus gallinarum, fowl pox virus, marek's disease virus, herpes virus of turkey, infectious laryngotracheitis virus, avian adenovirus, avian reovirus, infectious bursal disease virus, reticuloendotheliosis virus, avian leukosis virus, avian encephalomyelitis virus and newcastle disease virus were detectable in the sera obtained from these chickens in 3 generations at various ages. antibodies against i ...19806253742
development of delayed hypersensitivity in gnotobiotic mice.germ-free mice develop low levels of delayed hypersensitivity following exposure to sensitizing doses of sheep erythrocytes, compared to that seen in conventionally raised mice. infection of the germ-free animal with either salmonella gallinarum or salmonella pullorum was followed by extensive growth of the organisms within the intestine and the gut-associated lymphoid organs. as many as 5,000 viable salmonellae were recovered from the cecal and ileal peyer's patches as well as the mesenteric ly ...19806965376
report of pullorum disease in the somali democratic republic. 19817346909
[effect of therapeutic agents on the antibody titer and allergic reaction in fowl typhoid-pullorum disease].studies were carried out on the effect of furazolidon, spectam, esb-3 and altabactin on the production of agglutinins and the initiation and development of an allergic response in chickens affected with pullorum disease. it was found that these preparations, when used three times at intervals of 20 days, in the course of 10 days each time at the respective therapeutic rates led to the decrease in the titer of agglutinins in the treated birds as early as the tenth day from the beginning of treatm ...19816211823
a long-term serological study of a flock of chickens naturally infected with salmonella pullorum.the serological reactions of a group of chickens naturally infected with salmonella pullorum were observed for one year. the conventional whole blood test, rapid slide test and tube agglutination test were used in the study and compared with the microagglutination and microantiglobulin tests. results of the whole blood rapid slide and tube agglutination tests were as consistent as those produced with the microagglutination and microantiglobulin tests in detecting one third of the birds as reacto ...19817340098
the immunosuppressive effect of mycoplasma meleagridis on nonreplicating antigens.the humoral responses of mycoplasma meleagridis-free and -infected turkeys were compared following primary and secondary antigenic stimulation with inactivated salmonella pullorum or dinitrophenyl-bovine gamma globulin. the mycoplasma-infected groups had significantly lower antibody responses to both antigens. the suppression was more evident in the secondary response. the results suggest that the immune response in turkeys infected with m. meleagridis is similar to that of bursectomized chicken ...19816175300
immune response and disease resistance in chickens. i. selection for high and low titer to salmonella pullorum antigen.a selection experiment for high and low anti-salmonella pullorum antibody titer was carried out over four generations within the b1b1 blood group genotype in chickens. the study was aimed primarily at identifying different response patterns controlled by immune response genes linked to the b system, the major histocompatibility complex of the chicken. maximal divergence was obtained in the third generation of selection when agglutination titers of 1/320 and 1/80 in b1b1 high and low responders, ...19816267577
the quantitative clearance of bacteria from the bloodstream of rainbow trout (salmo gairdneri).the blood clearance of 51cr-labelled heat-killed salmonella pullorum was biphasic and exponential for each phase. this pattern was the same for all three concentrations of bacteria used. the initial more rapid phase lasted for approximately 15 minutes when roughly 90% of the bacteria had been cleared. the second slower phase started 25 to 30 minutes post-inoculation and lasted for approximately 25 to 30 minutes. the tissue distribution of bacteria showed that in both absolute and relative terms, ...19827147628
survey of the health and husbandry of small poultry flocks in great britain.an investigation into the health and husbandry of 15 small poultry flocks was undertaken. each flock was visited in july and a questionnaire on management practices and disease history was completed. the flocks were clinically examined and serological tests for salmonella pullorum, mycoplasma gallisepticum, m synoviae, m meleagridis, newcastle disease, infectious bursal disease, infectious bronchitis, eggdrop syndrome 76, adenoviruses and reoviruses were carried out. oesophageal and cloacal swab ...19826814044
[poultry resistance to typhoid-pullorum disease by sex and breed].studied was the resistance of a total of 1729 birds of the leghorn, cornish, and white plymouth rock breeds with regard to typhoid and pullorum disease after the oral infection with strain 2348 of salmonella pullorum and strain 2307 of salmonella gallinarum. in accordance with the manifested clinical picture and the results of the bacteriologic investigations all birds were divided into three groups--unaffected, survived, and died. there existed breed- and sex-associated variations in the resist ...19827168143
[differentiation of immunoglobulin classes in the chicken].investigations were carried out to establish and differentiate the humoral immunoglobulins in spf-chickens, following an antigenic stimulus with salmonella pullorum. as many as five components were found in the blood sera of the test birds, which were shown to have immunoglobulin properties. they were differentiated as igm, iga, igg1, igg2, and igg3. those of the iga-type were found in exudate material from the abdominal cavity of birds infected with salmonella pullorum. in the course of the inf ...19827112920
[phagocytic activity and antibody formation in relation to the resistance of poultry to fowl typhoid-pullorum disease].vulchanov's method (1954) was employed to study the phagocytic activity, and the classic method with the agglutination test served to follow up the production of antibodies. some breed-associated differences were observed in the phagocytic activity and the normal serologic antibody titer prior to the infection with salmonella pullorum and salmonella gallinarum. highest were the indices with the leghorn breed, followed by the cornish and plymouth rock breeds. certain breed differences were also e ...19827170772
concentration of salmonella pullorum antigen and the immunosuppressive effect of adrenocorticotropin in growing chickens.the role of antigen concentration on the immunosuppressive effect of adrenocorticotropin (acth) was tested in 6-week-old white rock chickens that were immunized i.v. with 1 ml of heat-treated salmonella pullorum at packed cell volume concentrations of .06 to .00015%, at 16 and 10 hr before the antigen (ag) injection, the birds received either 4 iu . 100 g body wt-1 of acth i.m., or the gelatin (gel) vehicle. total, 2-mercaptoethanol sensitive (2-mes), and 2-mercaptoethanol resistant (2-mer) aggl ...19836308589
[erythrocyte antigen for the rapid intravital diagnosis of fowl typhoid and pullorum disease].a stable erythrocyte antigen was obtained for the rapid diagnosis of typhoid and pullorum disease in birds, which was tested under laboratory and field conditions. it was found that with the use of whole blood or serum taken from birds that had been either experimentally infected or had died of spontaneous infection of salmonella gallinarum and salmonella enteritidis the erythrocyte antigen was substantially superior to the routinely used colour ordinary test-antigen in terms of time consumed, i ...19836364560
agglutinin responses to salmonella pullorum in japanese quail selected for plasma cholesterol response to adrenocorticotropin and a model describing the dynamics of the response.japanese quail from the s16 generation of lines selected for high (hr) and low (lr) plasma cholesterol response to adrenocorticotropin (acth), and the randombred control line (c) from which the selected lines had been derived, were immunized with a heat-killed salmonella pullorum antigen. plasma from blood samples taken at 0,5,8, and 12 days postimmunization was titered for total agglutinin levels. a quadratic equation and its first derivative, calculated for each bird, produced mean values by l ...19846091085
the effect of temperature and starvation on the clearance of bacteria from the bloodstream of rainbow trout (salmo gairdneri richardson).the blood clearance of 51cr-labeled heat-killed salmonella pullorum was generally biphasic and exponential for each phase. starvation had little significant effect on this pattern, although the rate of first phase clearance was probably slower. raising the water temperature from 8 degrees c to 18 degrees c enhanced the rate of clearance of the second phase to almost exactly double that at 8 degrees c. at 18 hr postinoculation, the spleen contained much more radioactivity per gm than any other ti ...19846584517
immunological traits in generations 7 to 12 of two lines of japanese quail selected for high or low antibody response to newcastle disease virus.several immunological traits were compared in lines of japanese quail selected for high and low secondary immune responses to anti-newcastle disease virus (ndv). the high line of quail, selected for high ability to produce antibodies, was more responsive in both their primary response to ndv antigen used in the selection as well as to other antigens used in selection process including ndv (ishi strain), tissue culture-derived newcastle disease (tcnd strain), ndv strain b1, influenza virus, sheep ...19846473242
interaction of high temperature and salmonella pullorum antigen concentration on serum agglutinin and corticosteroid responses in white rock chickens.in three experiments, 6- to 7-week-old chickens were exposed to one or two standard heating episodes and were injected immediately afterward with different concentrations of heat-killed salmonella pullorum antigen (ag) or phosphate-buffered saline. the standard heat episode consisted of three .5-hr exposures of 44 to 46 c with .5-hr periods of 22 c between exposures. nonheated chickens were maintained at 22 c. when two heating episodes were used, there was a 12-hr interval between episodes. sera ...19846531335
[acute pullorum disease in hawk-headed parrots (deroptyus accipitrinus fuscifrons)]. 19854023688
splenic leukocytes from chickens injected with salmonella pullorum antigen stimulate production of corticosteroids by isolated adrenal cells.corticosteroid levels in the blood serum of white rock pullets were significantly increased within 1 hr after an iv injection of heat-killed salmonella pullorum antigen (sp-ag), and reached levels 7 to 10 times that of pbs-injected controls within 2 hr after sp-ag injection. incubations with isolated adrenal cells indicated that serum from sp-ag-injected birds had the ability to stimulate the synthesis or release of corticosteroids twice that of serum pbs-injected birds. stripping the serum from ...19852984689
relationship between immune system and gram-negative bacteria, binding of salmonella pullorum-gallinarum to chicken lymphocytes.salmonella pullorum-gallinarum binding to chicken lymphocytes has been evaluated in individuals of different age (1-20 wks). bacterial adherence has been studied on lymphoid cells recovered from thymus, spleen, bursa and peripheral blood. binding was age-dependent and neuraminidase treatment of lymphoid cells led to an increase of adherence. in addition, by using two monoclonal antibodies, the ct-1, which defines thymocytes and the m-4 which identifies surface igm and an avian homologue of mamma ...19863542555
genetic aspects of antibody responses in chickens to different classes of antigens.six breeding groups of chickens, each characterized by a different haplotype of the b blood group system, were challenged with different classes of antigens, namely newcastle disease vaccine (nd), infectious bronchitis vaccine (ib), infectious bursal disease viral agent (ibd), salmonella pullorum antigen (p), and sheep red blood cells (srbc). parents were challenged at 20 weeks of age, and their offspring were challenged at 3 weeks of age. blood samples were taken from the parents at 1 week afte ...19863703775
increased collateralization of the cerebellothalamic pathway following neonatal hemicerebellectomy.the postlesional reorganization of the cerebellothalamic cells was here studied using a multiple retrograde tracing technique. to this purpose, the cerebellothalamic cell population was investigated in 3 groups of adult rats: (a) cases hemicerebellectomized at birth; (b) cases hemicerebellectomized in adulthood; and (c) control unlesioned ones. in all of the groups the fluorescent tracers diamidino yellow and fast blue were injected bilaterally in the thalamus and the retrograde labeling obtaine ...19863708349
production, physiological, and behavioral responses of laying hens in different management environments.responses of commercial laying hens to 16 management systems were examined for 10 laying periods of 28 days each. twelve cage treatments consisted of housing three, four, or five hens in deep and shallow cages of different dimensions which provided .035 and .046 m2/hen. four floor treatments housed 35 hens or 32 hens and three roosters at densities of .094 or .373 m2/bird, in two replicated pens each. quantitative data were collected simultaneously for 23 production, physiological, and behaviora ...19873601849
fatal case of salmonellosis (salmonella pullorum) in a chimpanzee (pan troglodytes) in the jos zoo.a case of salmonellosis in a captive chimpanzee (pan troglydytes) is reported. confirmatory diagnosis was based on clinical signs, necropsy and histopathological examination, and the isolation of salmonella pullorum from the lung, liver, kidney and intestines of the animal. the source of infection was not ascertained.19873682095
effects of bumetanide on chloride transport in human eccrine sweat ducts: implications for cystic fibrosis.the effect of the loop diuretic bumetanide on cl- transport in the human reabsorptive sweat duct (rsd) was studied to determine the properties of cl- transport in this tissue with an emphasis on its role in cystic fibrosis. bumetanide (10(-4) m) in the bath decreased the nacl reabsorption rate (+/- se) from 235 +/- 72 to 77 +/- 24 pmol/min per mm (n = 10). bumetanide in the lumen decreased the rate of nacl reabsorption to a lesser extent from 132 +/- 17 to 84 +/- 16 pmol/min per mm (n = 9). at l ...19873440743
evaluation of the efficacy of apramycin against salmonella pullorum infection in chickens.the efficacy of apramycin given orally at dose levels of 225, 150 and 75 mg/litre for five days to chicks experimentally infected with salmonella pullorum has been evaluated. the results show that this drug, when utilised at the dose level of 225 mg/litre for five days, totally suppresses mortality and significantly reduces salmonella excretion in comparison with non-treated chicks.198718766617
the association between a large molecular mass plasmid and virulence in a strain of salmonella pullorum.eight strains of salmonella pullorum isolated from epidemiologically independent cases of pullorum disease (bacillary white diarrhoea) in young chickens possessed at least one large molecular mass plasmid in addition to smaller molecular mass plasmids. the 85 kb large plasmid, designated pbl001, of one of these strains was 'tagged' with an ampicillin resistance marker by the insertion of transposon tn3. the plasmid was eliminated by passage in nutrient broth containing acridine orange. it was re ...19883253408
detection of salmonellas in confectionery products by conductance.a modified lysine decarboxylase broth has been developed which could be used with a bactometer m123 to differentiate salmonellas from other bacteria by the characteristics of the conductance detection curve. the medium was used in combination with a selenite cystine trimethylamine oxide dulcitol medium to screen 50 strains of salmonellas and 42 strains of other organisms to establish detection curve magnitude and rate values which could be used to identify curves specific to salmonellas. the com ...19883049504
protective role of serum antibody in immunity to chlamydial genital infection.female guinea pigs were injected intraperitoneally with pooled immunoglobulin derived from animals immunized to the chlamydial agent of guinea pig inclusion conjunctivitis. genital infections in animals receiving pooled immunoglobulin from immune animals were markedly decreased with regard to the number of inclusions detected compared with control animals. these data indicated that serum-derived antibody was able to provide a degree of protection against a chlamydial genital tract infection.19892909492
effects of aflatoxin on the immune system of the chick.a decreased antibody response to injected sheep red blood cells and weight losses to the extent of 25-38% were observed in the bursa fabricii and thymus in chicks fed an aflatoxin diet (10% w/w) for 3 weeks. the immune organs did not show any significant histopathological changes. the antibody titre decreased from day 6 of treatment onward until the 15th day, when the antibody titre had disappeared completely in the test chicks. the body weight gain was also less in test chicks (9.7-37.3%) given ...19892778263
[therapy trials with enrofloxacin (baytril) in a laying hen flock with salmonella pullorum infections].the course of a disease due to salmonella pullorum in laying chickens is described. the experimental application of enrofloxacin (baytril) at a dosage of 100 mg/l drinking water for 10 days resulted in a stop of the mortality rate, increment of egg production and reduction of salmonella excretion. a recurrence of the disease was observed in the fifth week following the end of treatment with high mortality and decreasing egg laying. the treatment lead to a short-dated success but a permanent elim ...19892651079
[salmonella gallinarum field isolates of the biovars pullorum and gallinarum].in 40 cases salmonellae of the serovar salmonella (s.) gallinarum were culturally isolated from domesticated gallinaceous birds submitted for diagnostic purposes in the period of 1979-1989. on the basis of the cultural and biochemical features found 35 of them could be assigned to the biovar pullorum and 5 to the biovar gallinarum. of 35 isolates of the biovar pullorum, 29 were isolated from pure bred chickens of small fancy-exhibition type flocks, 4 from floor-housed adult brown hybrid laying h ...19892764874
immunity to experimental fowl typhoid in chickens induced by a virulence plasmid-cured derivative of salmonella gallinarum.chickens were immunized by two intramuscular inoculations at 1 and 14 days of age with virulence plasmid-cured derivatives of salmonella gallinarum and were challenged 14 days later by oral inoculation of ca. 50 50% lethal doses (ld50) of fully virulent s. gallinarum 9. mortality in the nonimmunized and immunized groups were 36 and 3%, respectively. this difference was highly significant (p less than 0.01). a significant reduction in mortality was also produced following oral challenge with 5,00 ...19902194968
a survey of infectious diseases in wild turkeys (meleagridis gallopavo silvestris) from arkansas.wild turkeys (meleagridis gallopavo silvestris) trapped as part of a relocation program by the arkansas game and fish commission were tested for selected infectious diseases and parasites. the 45 birds were trapped at four locations in pope, scott, and montgomery counties (arkansas, usa). forty-four blood samples for serology, 27 blood smears and 12 fecal samples were collected. of the serum samples tested, 20 of 44 (45%) were positive for pasteurella multocida by enzyme-linked immunosorbent ass ...19902250323
[pathologico-anatomic, bacteriologic and serologic findings in laying hens from small neighborhood flocks with salmonella enteritidis phage type 4 infection].two small free range flocks with 32 hens, whose salmonella enteritidis contaminated eggs caused salmonellosis in man, were investigated for localisation of the agent. salmonella enteritidis phage type 4 was isolated from 12 of 32 hens (37.5%). eight hens (25%) harbored the bacterium in the ovary and/or the oviduct. the rapid slide agglutination test with salmonella pullorum-antigen revealed 21 positive hens (66%). all eight hens with salmonella enteritidis phage type 4 in the reproductive tract ...19912047834
health survey of backyard poultry and other avian species located within one mile of commercial california meat-turkey flocks.a survey was conducted to characterize domestic and exotic bird populations, estimate seroprevalence to selected disease agents, and describe health management practices on 62 premises containing "backyard" flocks located within one mile of 22 commercial california meat-turkey flocks participating in national animal health monitoring system (nahms). chickens were present on 56 backyard premises and turkeys on seven. antibodies were identified against mycoplasma gallisepticum, m. synoviae, m. mel ...19911854324
detection of salmonella serogroup d-specific antibodies in the yolks of eggs laid by hens infected with salmonella enteritidis.eggs laid by hens experimentally infected with salmonella enteritidis were assayed for the presence of serogroup d-specific yolk antibodies. yolk antibodies were detected with s. enteritidis and salmonella pullorum antigens in the microantiglobulin test as early as 9 days after inoculation of hens with s. enteritidis. yolk antibody titers reached peak levels at 3 to 5 wk postinoculation and remained at detectable levels for at least 7 wk postinoculation in eggs from both orally inoculated and ho ...19911852702
measurement of alkaline phosphatase activity in serum with n-methyl-d-glucamine as a buffer: evaluation of the method for routine use.some aspects of the measurement of alkaline phosphatase activity concentration in human serum, using n-methyl-d-glucamine as a buffer, were evaluated with a view to the possible routine use of the method. the evaluated characteristics included: the temperature-dependence of the ph of the buffer; the effect of adding the magnesium/zinc ions buffer; the effect of the serum volume fraction; the substrate-starter versus the serum-starter mode; the effect of modifying the formulation of reagents; the ...19911782284
progeny performance when dams and chicks are fed supplemental zinc.three consecutive trials involving approximately 700 to 800 broilers (0 to 28 days) were conducted to examine effects on growth and immunity of chicks after supplementing dams with inorganic zn versus organic zn. offspring from hens fed a basal diet (72 mg zn/kg) or diets with 152 mg zn/kg supplemented with zno or organic zn-met were randomized across four battery brooders. chicks were fed a starter diet without supplemental zn containing 100 mg zn/kg or diets supplemented with 40 mg/kg zn from ...19921641384
pathogenicity of salmonella pullorum in northern bobwhite quail and mallard ducks.ten-day-old northern bobwhite quail and mallard ducks were inoculated orally and intravenously with salmonella pullorum at selected concentrations (10(3) to 10(10) colony-forming units). mortality in bobwhites ranged from 65% to 100%, whereas no mallards died or exhibited any signs of morbidity. significantly (p less than 0.05) increased values for serum calcium, uric acid, and lactate dehydrogenase were observed in mallards inoculated with live s. pullorum, and antibody titers were detected as ...19921627103
pullorum disease in delaware roasters.an index case of pullorum disease in 4-week-old roasters from a completely integrated poultry operation is reported from delaware. severe articular and periarticular swelling of hock and/or wing joints was observed on postmortem examination. also seen were moderate to severe hydropericardium and large white-gray nodules in the heart and gizzard that grossly could have been taken for tumors. the livers showed multiple small white foci, petechial hemorrhages, and swelling. initially, salmonella pu ...19921485862
[the selection of salmonella gallinarum, salmonella pullorum and escherichia coli in chickens after chloramphenicol administration].the effect of a chloramphenicol administration was examined on the selection of e. coli of the chicken intestinal flora, and of the infectious s. gallinarum and s. pullorum strains. on the other hand, an effort was made to detect the frequency of the resistance transmission of e. coli to above mentioned sensitive salmonella strains. fourteen chicken, 12 infected and 2 negative controls were used. it was found that the enteric e. coli strains became resistant in a week's time. besides, the strain ...19921471974
antibacterial activity and mutagenicity studies of water-soluble phosphazene high polymers.eight water-soluble phosphazene high polymers, [npr2]n (r, organic, water-solubilizing side-group; n, approx: 15,000) and the small-molecule counterparts of the polymers were examined for antibacterial activity against six different strains of bacteria (escherichia coli, salmonella typhimurium (ta 100), salmonella pullorum, streptococcus faecalis, bacillus subtilis and pseudomonas aeruginosa). antibacterial testing was carried out by measuring zones of inhibition and changes in solution turbidit ...19921457679
epizootiological investigation of an outbreak of pullorum disease in an integrated broiler operation.an integrated broiler company experienced a major outbreak of pullorum disease during 1990. the outbreak resulted in the distribution of salmonella pullorum-infected birds to more than 150 roaster flocks in five states. twenty-two parent (multiplier) breeder flocks became infected. an epizootiological investigation uncovered a grandparent male line breeder flock as the index flock supplying males to the affected parent flocks. transmission apparently occurred vertically through the egg and horiz ...19921417613
serological response of chickens to infection with salmonella gallinarum-s. pullorum detected by enzyme-linked immunosorbent assay.the serological response to salmonella pullorum and s. gallinarum infection in chickens was studied with an indirect enzyme-linked immunosorbent assay (elisa). in broiler chickens, a more virulent strain of s. pullorum produced a significantly lower serum igg titer than did a less virulent strain. in laying hens, the serum and egg-yolk igg titers were very similar. in chickens infected with s. gallinarum, high igg titers persisted for 30 weeks. in chickens reinfected with this strain, each reinf ...19921385699
cloning and nucleotide sequence of the gene (citc) encoding a citrate carrier from several salmonella serovars.the nucleotide sequence of the citc coding for the citrate carrier in several salmonella serovars has been determined, and the amino acid sequence of the carrier protein was deduced. the predicted citrate carrier from salmonella pullorum and salmonella enteritidis consists of 446 amino acids with a molecular weight of 47,621, whereas that from salmonella dublin is the same 446 amino acids with the slightly different molecular weight of 47,591, because 1 amino acid residue was substituted. the pr ...19921374406
pullorum disease with unusual signs in two backyard chicken flocks.atypical pullorum disease in two backyard chicken flocks occurred as sudden death of many adult birds in one backyard chicken flock and chronic wasting with high mortality in a second flock. chicks had been added to both flocks for several months before losses occurred. the chicks, which were not affected, came from a previously infected hatchery that did not totally depopulate.19938257389
bacteriological, serological, histological and immunohistochemical findings in laying hens with naturally acquired salmonella enteritidis phage type 4 infection.salmonella enteritidis phage type 4 was isolated from the reproductive tract of 10 (27 per cent) of 37 laying hens from three small flocks with a naturally acquired infection. the rapid slide agglutination test with salmonella pullorum-antigen was positive in 24 (64.9 per cent) of the 37 hens including the six hens in which the ovary was colonised and the 10 in which the oviduct was colonised. by immunohistochemical labelling s enteritidis was demonstrated in seven of eight culture-positive hens ...19938310606
evolutionary origin and radiation of the avian-adapted non-motile salmonellae.multilocus enzyme electrophoresis was employed to estimate chromosomal genotypic diversity and relationships among 131 isolates of the non-motile salmonella biotypes gallinarum and pullorum (serotype 1, 9, 12:-:-) that cause fowl typhoid and pullorum disease, respectively. thirteen electrophoretic types (ets), marking clones, were distinguished, and construction of a neighbour-joining phylogenetic tree revealed three lineages: one consisted of five ets of gallinarum, a second included seven ets ...19938429538
research note: differential chemotaxis of physarum polycephalum to salmonella gallinarum and salmonella pullorum.the chemotactic and chemotropic responses of the plasmodial stage of the slime mold physarum polycephalum were used to distinguish salmonella gallinarum and salmonella pullorum from 10 salmonella serovars that are commonly isolated from domestic poultry. utilizing an in vitro plasmodium agar plate assay method, p. polycephalum was attracted to s. gallinarum and s. pullorum, but the organism was repelled by salmonella derby, salmonella dublin, salmonella enteritidis, salmonella heidelberg, salmon ...19938479960
salmonella pullorum infection and pheasants. 19938291181
salmonella control--past, present and future.the perception of salmonella infection as a problem to the poultry industry has changed as the industry itself has changed. other factors include increasing awareness of health and food quality. acquisition of more information on the microbiology of salmonella and the epidemiology of infection in poultry and man, have not, with a few exceptions, enabled us to eliminate salmonella from poultry and from the food chain. control of the poultry pathogens s. pullorum and s. gallinarum, the major patho ...199318671051
evaluation of the humoral immune response to different antigens in arkansas regressor and progressor chickens.arkansas regressor and progressor chickens were re-evaluated for their immune response to different antigens. chickens received i.v. injection of either srbc (10 birds per line) or salmonella pullorum (sp; 10 birds per line) at 7 wk of age, and sera were collected at 6, 13, and 20 d postimmunization. a third group of birds (10 birds per line) received and i.m. injection of gat emulsion at 7 and 12 wk of age, and sera were collected at 10 and 14 wk of age. there were significant differences betwe ...19948146082
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