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phenylalanine inhibited p-nitrophenyl phosphatase activity in the serum as an indication of intestinal cellular disruption in the horse.examination of tissues obtained from thoroughbred horses showed that the 'intestinal' phosphatase activity could be differentiated from other phosphatases by analysis at a ph of 9-5 and inhibition with 15 mm l-phenylalanine. a simple method for the measurement of 'intestinal' phosphatase in heparinised plasma or serum is described. application of the technique to serum or plasma from normal and diseased horses indicates that the increase in the activity of 'intestinal' phosphatase is associated ...197722115
salmonella gallinarum - salmonella enteritidis relationship in rabbits.the polysaccharide of s. gallinarum, sharing factors 9.12 with the salmonellae of group d. cross-reacts with one of two serological determinants, present in the polysaccharide of s. enteritidis, and is different from the determinant responsible for the cross-reaction of s. enteritidis and s. typhy polysaccharides. the absorption of anti s. gallinarum sera with proteins from s. enteritidis removed all the antibodies induced for the homologous antigens; in contrast, the absorption of the anti s. e ...197766825
[introduction of an additional h-agglutinating test antigen for the differentiation of specific positive reactions in pullorum disease-fowl typhoid in poultry experimentally infected with salmonella gallinarum-pullorum and salmonella enteritidis].explored were the possibilities to differentiate the specific positive reactions in case of pullorum disease in experimentally infected (salmonella gallinarum-pullorum and salmonella enteritidis) birds with the use of a typhoid test antigen and two h test antigens, obtained by the routinely employed method with formalin from salmonella enteritidis and salmonella adeoyo. it was demonstrated that the h-agglutinating antibodies persisted in the peripheral blood of the experimentally infected birds ...197775606
[indirect hemagglutination reaction in pullorum disease-fowl typhoid]. 197880877
effect of toyocamycin on the synthesis of the 70s rna of a murine retrovirus.the murine eveline cell line chronically infected by friend virus was treated with toyocamycin (tmc), an adenosin analog and the virions released in the presence of the drug were examined for their rna. it was found that 70s rna which was synthesized incorporated toyocamycin. however, its subunit structure and its poly (a) content were apparently preserved. this incorporation may explain loss of endogenous reverse transcriptase activity.197988041
complications associated with therapeutic soft contact lenses.the complications of therapeutic hydrophilic contact lens wear are systematically outlined. hypoxia is the major cause of initial patient failure as well as the long-term problems of corneal edema, neovascularization, and susceptibility to infection. the common difficulties with lens breakage, lens deposits, poor lens retention, and other entities are discussed. suggestions for avoiding and treating various complications are given, including updated indications and contraindications for fitting ...200193261
fetal erythropoiesis in stress hematopoiesis.fetal erythropoiesis occurs during chronic bone marrow failure, or during recovery from marrow suppression. fetal erythrocytes have hb f, with more g gamma than a gamma chains, "i" antigen, large mcv, characteristic enzyme levels, low carbonic anhydrase, low hb a2, and short life span. many of these fetal characteristics are present in the red cells of patients with temporary or chronic hematopoietic stress. in those in whom normal hematopoiesis ensues, the fetal erythrocytes disappear. the feta ...199895616
hemolysis induced by cefazolin and cephalothin in a patient with penicillin sensitivity.a patient with penicillin sensitivity, who had never received a cephalosporin antibiotic previously, developed anemia and spherocytosis following the administration of cefazolin. hemolysis abated when the drug was discontinued on the fourth day, and recurred on day six when cephalothin therapy was begun. igg and complement components were present on the patient's erythrocytes, and igg antibodies in her serum reacted with normal red blood cells which had been coated with benzylpenicillin, cefazol ...199996555
interconversion and characterization of d and i forms of glycogen synthase from frog muscle. 199996859
picosecond detection of bchl-800 as an intermediate electron carrier between selectively-excited p870 and bacteriopheophytin in rhodospirillum rubrum relaction centers. 197897097
chemosensory responses of swimming algae and protozoa. 200097241
[physiologic effects of altered gravitation]. 200197873
post-traumatic epilepsy. 200198198
fine structure and evolution of dna in heterochromatin. 200198264
evaluation of possible mutagenicity of the condiment clove when administered alone or in combination with caffeine in drosophila melanogaster. 200098437
transplantation of preserved pancreatic islets into the portal vein of rats.langerhans islets were isolated from the exocrine pancreata of wistar rats by the improved collagenase-digestion method. the isolated islets were preserved in a tissue culture medium for seven days. transplantation of these preserved islets into the portal vein of streptozotocin-induced diabetic rats resulted in a significant reduction of hyperglycemia, polyuria and glucosuria, and a restoration of weight gain. it was found that these effects could be maintained for 16 weeks. in order to normali ...197898659
morphologic effects of thio-tepa on mammalian urothelium. changes in abnormal cells.morphologic changes induced by thio-tepa were examined in animals with chemically induced neoplasms. both toxic and metabolic effects were documented. degeneration, vacuolization and increased exfoliation (toxic) were most prominent, occurred within 48 hours of exposure, and tended to subside after removal of the drug. nuclear changes (metabolic) were rare and occurred late. neither toxic nor metabolic effects were specific for thio-tepa: both could be detected in control animals receiving salin ...1998104512
the future of laam. 1998106294
subsite interactions and ribonuclease t1 catalysis: kinetic studies with apgpc and apgpu. 1998107963
basic findings and current developments in sphingolipidoses.sphingolipidoses are caused by recessively inherited deficiencies of lysosomal hydrolases. the clinical backgrounds of and current biochemical and genetic approaches to the different forms and variants of gangliosidoses, trihexosylceramidosis (fabry's disease), galactosylceramidosis (krabbe's disease), sulfatidoses (metachromatic leukodystrophies), glucosylceramidosis (gaucher's disease), sphingomyelinoses (niemann-pick disease) and ceramidosis (farber's disease) are presented.1998108196
bacteriophage t4-coded dihydrofolate reductase: synthesis, turnover, and location of the virion protein.dihydrofolate reductase plays a dual role in bacteriophage t4, first, as an enzyme of thymidylate metabolism, and second, as a protein component of the tail baseplate. antibody to the purified enzyme has been used to study its synthesis and intracellular turnover. the antibody specifically precipitates one protein from t4d-infected cell extracts. this has been identified as dihydrofolate reductase, although the polypeptide molecular weight (22,000) is lower than that earlier determined for this ...1979116011
[economic effectiveness of antibiotics in pullorum disease-fowl typhoid in poultry]. 1976139739
pompe's disease presenting as hypertrophic myocardiopathy with wolff-parkinson-white syndrome. 1964277063
production of precipitating antibodies in chickens infected with salmonella gallinarum.vaccination of 10 days old chicken with a live relatively avirulent s. gallinarum induced antibodies against the main antigens of the pathogen, namely, its proteins. precipitations in agar gel were obtained against the free proteins and the protein conjugated in the somatic antigen of s. gallinarum and against antigens from the related s. enteritidis. antipolysaccharide antibodies were induced in small quantities which were however sufficient to allow their identification with the agar-gel-diffu ...1977322427
the history of avian medicine in the u.s. ii. pullorum disease and fowl typhoid. 1977334148
[immunogenicity in salmonella gallinarum-pullorum irradiated with gamma rays].studied with the imunogenicity of salmonella gallinarum-pullorum bacteria treated with 1, 10 and 20 mr gamma rays or killed with acetone. bacterial cultures were irradiated with a lmb-gamma m device, having a 137cs source, single doses being of a 3,252 r/min power biozzi's clearance test was employed to determine the changes in the immunogenic properties of the irradiated bacteria. the results obtained with both the clearance test and the protection test spoke of a considerable drop in the immun ...1977343353
[use of an immunoadsorbent in differentiating b and d salmonelloses in poultry].an immunoadsorbent was obtained from a lipopolysaccharide of salmonella gallinarum-pullorum, employing the method of eskenazy. it was used to adsorb the o agglutinating antibodies against s. gallinarum-pullcorum, s. enteritidis, s. heidelberg in blood sera of birds. adsorption of sera was carried out at room temperature for 40 min. it was demonstrated that the product was highly specific. it fully and specifically found the o agglutinating antibodies in the sera of birds infected with s. gallina ...1977343356
[effect of protein in the feed on the resistance of poultry artificially infected with salmonella galinarum pullorum and salmonella typhimurium].studied is the effect of the low protein level in rations of birds, experimentally infected with salmonella gallinarum-pullorum and salmonella typhimurium. birds of different ages of the leghorn and cornish breeds are included in the experiments. results obtained from the experiments indicate that the lowered level of protein in rations to young birds at the age of five months makes them more resistant to salmonella infection. this dependence is markedly demonstrated in particular in the case of ...1978380135
the effect on the virulence and infectivity of salmonella typhimurium and salmonella gallinarum of acquiring antibiotic resistance plasmids from organisms that had caused serious outbreaks of disease.antibiotic resistance plasmids from organisms that had caused serious epidemics, including those responsible for epidemics of chloramphenicol-resistant typhoid fever and dysentery in central america, were transferred to a strain of salmonella typhimurium and of salmonella gallinarum. the virulence and infectivity of these r(+) forms were then compared with the r(-) parent forms in orally inoculated chickens.none of the r(+) forms were more virulent than their r(-) parent forms. the mortality rat ...1979385769
cross-protection aginst salmonella enteritidis infection in mice. i. immunization trials.mice were immunized subcutaneously with live and killed vaccines, with and without complete adjuvant incorporating salmonella typhi-murium m206, salmonella gallinarum 9r, salmonella pullorum sp223 as well as homologous salmonella enteritidis se795. the animals were challenged 21 days post-vaccination with 100 ld50 of virulent s. enteritidis 5694 smr subcutaneously along with unvaccinated control mice. to assess the immunity against acute and chronic infections, the percentage of absolute survivo ...1979397731
cross-protection against salmonella enteritidis infection in mice.mice were immunized subcutaneously with live vaccines and live vaccines with complete adjuvant incorporating salmonella enteritidis se 795, salmonella typhi-murium m206, salmonella gallinarum 9r or salmonella pullorum sp223. they were challenged along with unvaccinated controls with 100 ld50 of virulent s. enteritidis 5694 smr subcutaneously on the 21st day post-vaccination. the humoral immune response was studied by assessing the sequential level of agglutinins, complete and incomplete somatic ...1979397732
cross-protection against salmonella enteritidis infection in mice. iii. delayed hypersensitivity reaction and clearance of the challenge organism.mice were immunized with live vaccines and with live vaccines with complete adjuvant incorporating salmonella enteritidis, salmonella typhi-murium, salmonella gallinarum or salmonella pullorum. on the 21st day after vacination, the hypersensitivity reactions elicited by the mice to extracts of the challenge organism (s. enteritidis 5694 smr) were assessed. the degree of delayed hypersensitivity reaction was compared with the level of protection induced by the vaccine. the role in protection of d ...1979397733
diffuse varioliform gastritis.during 8 years experience, 90 cases of diffuse varioliform gastritis were observed (0.3% of examinations). symptoms suggest either the presence of a gastroduodenal ulcer or of a digestive carcinoma when weight loss is prevalent. the disease proceeds by subacute evolutive bouts with remissions and further relapses. at endoscopy, lesions associate large folds in the fundus and erosive mucosal bulgings disseminated in the fundus and antrum. histological alterations correspond to a superficial hyper ...1974414953
studies on the ameliorating effect of ascorbic acid on mineral toxicities in the chick.the effect of dietary ascorbic acid on the toxicity of high levels of cobalt, selenium, vanadium, cadmium, copper, and mercury was determined in chicks. the vitamin reduced the growth retardation caused by cobalt, selenium, vanadium, and cadmium administration but had no such effect on copper and mercury toxicity at the levels used. the effect of ascorbic acid on growth could not be mimicked by ferrous iron administration. ascorbic acid did not alleviate the increased susceptibility of chicks to ...1979430217
dietary influences on resistance to salmonella infection in chicks.studies on the influence of nutritional factors on the resistance of chicks to salmonella gallinarum have been reviewed. increased dietary protein decreased the resistance of chicks to this infection although resistance to escherichia coli infections was not appreciably affected. the administration of high levels of iron, particularly when accompanied by a chelating agent such as edta, resulted in increased resistance to this infection. the additional iron resulted in the prevention of the trans ...1979446767
[diagnostic value of the indirect hemagglutination reaction in pullorum disease-fowl typhoid]. 1979452403
[effect of surgical bursectomy in young turkey hens on body weight and on the resistance against salmonella gallinarum-pullorum infections]. 1979486063
[serum enzymatic activity in acute injury to the renal parenchyma].studied was the activity of the serum enzymes lap, ce, aph, sph, and guanase as well as the isoenzymes of the unspecific esterases and aph in guinea pigs treated with potassium bichromate. morphologically and histopathologically, an acute injury of the kidney parenchyma was found, being in close correlation with the size of lesions and these enzymes' activity. the activity of aph, sph, and ce rose, and that of lap and guanase did not change. these enzymes proved to form an appropriate constallat ...1979516440
[the excretory apparatus and diabetes]. 2005545627
lymphocyte markers and circulating immune complexes in primary glomerulonephritis. 2005549018
production and application of a live salmonella gallinarum vaccine.the production and application of a freeze-dried salmonella gallinarum vaccine are described in this report. the vaccine is stable when kept at 4 degrees c and a single injection elicits a good immunity for 2 months, though its effect gradually diminishes. immunity is neither enhanced nor depressed by repeated injections of the live vaccine, and no interference effect was observed in experimentally infected chickens. furazolidone therapy jeopardizes the immunogenicity of a live vaccine, but its ...1979551367
the influence of protein source and basal dietary component on survival in acute experimental fowl typhoid in the chick (gallus domesticus).1. the influence of diet on the survival of chicks inoculated orally at 15 d of age with salmonella gallinarum was determined, and in the first experiment the numbers of salmonellae were counted in blood 5 or 7 d after inoculation to assess their value in predicting survival. 2. significantly more chicks survived among those given beef powder as the protein supplement in a starch-based diet than among those where fish flour replaced beef powder. the number of salmonellae in blood was significant ...1977588545
[changes in the toxic, antigenic and immunogenic properties of the o-antigen of salmonella gallinarum-pullorum irradiated with gamma rays].studied was the effect of gamma-rays at rates of 1 to 20 mr on the toxic, antigenic, and immunogenic properties of the o-antigen extracted from salmonella gallinarum-pullorum by the method of boivin. it was found that the irradiation of aqueous solutions of the o-antigen lowered the toxic, antigenic, and immunogenic capacity with the increase in the dose of treatment. strongest detoxication of the endotoxin was produced through irradiation at the rate of 10 mr, and especially at 20 mr. the antig ...1977595373
increased survival from acute salmonella gallinarum infection in chicks given diets with high levels of some forms of iron.amounts exceeding 100 ppm of extra dietary iron as the ferric salts of ethylenediaminetetra-acetic acid (fee) or nitrilotri-acetic acid (fen) produced highly significant increases in survival among chicks infected with 10(6.4) living salmonella gallinarum strain 9. additional dietary iron (400 ppm) as the sulphate or chloride salts (or as ferric fructose) lacked activity comparable with fee or fen except when 0.2 per cent of nae was also present in the diet. fee iron (600 ppm) also diminished th ...1977605293
a fowl typhoid outbreak in a chicken breeder flock.fowl typhoid was diagnosed in a 1-year-old light-breed brown-egg-laying chicken breeder flock and in a 16-week-old progeny pullet flock on the same farm. salmonella gallinarum was cultured from chickens in both flocks. signs and lesions were typical. the disease was confined to the one farm. the source was suspected to have been a grossly contaminated well.1977606229
[diagnostic value of serological methods and of the allergy method in studying pullorum disease-fowl typhoid in poultry].it was established that the positive allergy reaction was best expressed at the forty-eighth hour following the introduction of the allergen. the diagnostic value of the allergy reaction was not shown to surpass that of the serum agglutination reaction. it proved to be close to the value of the other serologic methods of examination (the whole-serum and whole-blood agglutination tests). the allergy method of investigation could be used as a tentative method, resp., reaction test for the detectio ...1977607558
experimental induction of an immunohaemolytic anaemia in the chicken with salmonella gallinarum endotoxin.the possibility that the extreme refractoriness of the chicken to injected endotoxin would permit the buildup of sufficient free endotoxin in the circulation to immunologically modify the erythrocytes in vivo and thereby cause them to be eliminated from the circulation was investigated. it was shown that a moderately severe immunohaemolytic anaemia accompanied by a mild spenomegaly could be induced in chickens by single (large) or multiple injections of salmonella gallinarum endotoxin (sge). var ...1978647450
haematological, serological and pathological effects in chicks of one or more intravenous injections of salmonella gallinarum endotoxin.abnormalities appeared a few hours after groups of 14-day-old chicks (gallus domesticus) were injected intravenously with 15 mg/kg of endotoxin (lps) from salmonella gallinarum. clinical illness without mortality was accompanied by significant (p less than 0.05) falls in body temperature, bursa weight, the main haematological parameters, serum iron (si) and transferrin saturation (ts) and a significant increase in unsaturated iron-binding capacity. all responses, apart from bursa weight, si valu ...1978653115
the anaemia in fowl typhoid: immuno-pathogenesis and associated patterns of erythrocyte destruction. 1978659679
[combined vaccines in veterinary medicine in the developing countries].it is in the interest of developing countries to have combined vaccines in veterinary medicine, not so much because they reduce production costs, but rather because they increase convenience and efficacy concerning the logistics of prophylactic projects in the field, thus lowering the cost of these projects. their drawbacks are basically due to the biological compatibility of immunogens (possible immunosuppression by some viruses) and to the interaction of the various components when mixed, or w ...1978753663
[dynamics of agglutination in birds artificially infected with salmonella gallinarum-pullorum and salmonella typhimurium and treated with sulfaguanidine and furazolidone].canadian leghorn chickens were used to study the effect of sulfaguanidine and furazolidon on the dynamics of blood agglutinin formation. the birds were artificially infected with salmonella gallinarum-pullorum and salmonella typhimurium. at various intervals following infection they were treated with sulfaguanidine 1% tablets and 0.04% furazolidon. the level of agglutinins was determined by the methods of huddleson (whole blood agglutination reaction), the fast serum agglutination, the method af ...1976797104
experimental fowl typhoid in chicks impaired immunologically by treatment with cyclophosphamide.male chicks were injected intramuscularly with 6 mg of cyclophosphamide daily for three consecutive days, the initial dose being given on the day of hatching. this treatment impaired bursal development and lymphopoiesis and no circulating antibodies appeared after such chicks were injected with salmonella gallinarum antigens at 19 and again at 26 days of age. in impaired chicks which were infected orally when 15 days old with s gallinarum the level of mortality was essentially the same as that i ...1977841202
enhancement of survival in acute experimental fowl typhoid in chicks by the administration of iron dextran.chicks aged 15 days were infected orally with 10(6-4) living salmonella gallinarum. iron from iron dextran or ferric ammonium citrate (dfe and cfe respectively), in doses of 2-0 or 0-4 mg/kg given intramuscularly at the time of infection, had no effect on subsequent mortality compared with infected controls. increasing the amount of cfe to the maximum (20 mg/kg) that was non-toxic intramuscularly was also ineffective but when the dose of dfe was increased to 20 or 50 mg/kg the survival rate rose ...1977870957
altered absorption and regulation of iron in chicks with acute salmonella gallinarum infection.chicks aged 15 days were infected orally with salmonella gallinarum. during the six-day period immediately following infection the absorption of 59fe from the gut fell progressively to be eventually about half that in noninfected chicks. this reduced uptake was accompanied by a shift in the distribution of the 59fe absorbed, more occurring in the spleen and less in the liver and blood. during the eight-day period that immediately followed infection in another experiment, serum iron concentration ...1977877434
[age-related dynamics of agglutinin formation in poultry experimentally infected with salmonella gallinarum-pullorum].agglutinin production in birds experimentally infected with salmonella gallinarum-pullorum directly correlates with age. the older the birds, the earlier setting on of agglutinogenesis, and the better the immune response. along with this agglutinins persist longer in the blood serum. it is suggester to carry out the first serologic examination in infected flocks of the leghorn breed when the birds are aged 50-55 days. this term may be essential only in cases where the birds have been infected at ...1977919340
[antibody dynamics in growing birds experimentally infected or naturally sick with white diarrhea].serologic studies were carried out with growing birds, aged 37-70 days, experimentally and spontaneously infected with salmonella gallinarum and salmonella pullorum, respectively. more positively reacting birds were found by means of the whole-blood agglutination reaction with typhoid-pullorum test than in the study of the same birds when aged 6-7 months. the investigation of birds when young is also advantageous in that there are no losses of eggs, it is more readily carried out, and the infect ...1977929972
a simplified biochemical system to screen salmonella isolates from poultry for serotyping.the 24 most frequently isolated paratyphoids from poultry, along with salmonella gallinarum and salmonella pullorum, plus strains of arizona, citrobacter, edwardsiella, escherichia, klebsiella, prteus, pseudomonas, serratia and shigella were inoculated into triple sugar iron (tsi) and lysine iron (li) slants and into six fermentation broths which were numbered: 1 (dextrose), 2 (lactose), 3 (sucrose), 4 (mannitol), 5 (maltose), 6 (dulcitol). all the salmonella cultures (except s. pullorum) gave a ...1976995819
[studies of various peculiarities of lysogenic salmonella gallinarum-pullorum variants]. 19761007952
[studies of bilysogenic and lysogenic salmonella gallinarum-pullorum variants obtained with infectious phage nucleic acid]. 19761007953
[experimental delysogenization of lysogenic salmonella gallinarum-pullorum variants with acridine dyes]. 19761007954
[comparative electron microscopic, biochemical and biological studies of initial strains, lysogenic and delysogenized variants of salmonella gallinarum-pullorum]. 19761007966
the absorption and distribution of 59fe in chicks with acute salmonella gallinarum infection [proceedings]. 19761028055
bactericidal and opsonic activities of normal sheep serum against gram-negative bacteria.the bactericidal and opsonic activities of normal sheep serum against 9 smooth and 4 rough strains of gram-negative bacteria were measured. three smooth strains-escherichia coli 3662, salmonella typhimurium, and salmonella gallinarum-were resistant to the bactericidal action of normal sheep serum with or without complement. six smooth strains-e coli o78:k80(b), salmonella arizonae, proteus inconstans, klebsiella pneumoniae, salmonella stanley, and salmonella abortus-equi-were moderately sensitiv ...19751098532
[diagnostic scheme of the causes of embryonal morbidity in poultry].a diagnostic scheme has been worked out to reveal the factors causing higher embryonic morbidity and mortality rates in birds. it is based on the morphologic analysis and the bacteriologic and mycologic studies, and can be programmed and put into effect in three stages in the course of 48 hours. on the one hand, the post-mortem analysis is useful in establishing the factors of noninfectious character (overheating, insufficient heating, humidity of low or high values, poor air exchange, improper ...19751108408
[dynamics of the agglutinin titer in chicks with pullorum disease-fowl typhoid]. 19751114666
[economic damage caused by mallophaga. v. attempt at determining the role of ecomenacanthus stramineus (nitzsch) in the transmission of fowl typhoid]. 19751121883
spinal subarachnoid hemorrhage with schwannoma. 20051181816
[possibilities of differentiation of the specific positive reactions for pullorum disease].studied were sera obtained from three groups of birds experimentally infected with salmonella gallinarum-pullorum. salmonella enteritidis, and salmonella heidelberg, resp., using the whole serum agglutination reaction, the slow test-tube reaction (at 37 degrees and 50 degrees c), and the agar gel precipitation reaction as modified by aoki as well as the spot-test of williams. it was found that with the use of a typhus antigen it is not possible to differentiate the positive coagglutination react ...19751210001
[role of ticks of the species argas persicus oken, 1818, in the epizootology of pullorum disease in birds].studies was the role played by ticks of the argas persicus species in the epizootiology of pullorum disease in birds. use was made of microbiologic, radiometric, and autoradiographic methods to follow up the period of carrying salmonella gallinarum-pullorum, the localization and routes of elimination of the causative agent as well as the possibility of transmitting the infection by ticks. the pathogen was found to persist in the alimentary tract for a long time (at least 8 months--as long as the ...19751210005
[veterinary genetics and selection].the article comprises the data on the genetic potentials of new-hampshire cocks determined on the basis of the resistance of their offspring to the artificial infection with salmonella gallinarum. it is shown that different cocks differ significantly from one another in their genetic potentials with respect to the resistance to salm. gallinarum. since the method of artificial infection can not be practiced always, it is proposed by the author to characterize the genetic potentials of animals by ...19751218714
study of salmonella gallinarum infection in chicks by gas liquid chromatography. 19751218915
[establishments of standards for noxious substances in the atmosphere]. 20051224696
[circular eye tracking test (cett)--the first report--simultaneous recording of horizontal ett and vertical ett, decrease of artifacts (author's transl)]. 20051236940
[clinical and etiological studies of glucocorticoid-reactive hypertension]. 20051236988
serum, disc and egg elisa for the serodiagnosis of salmonella gallinarum and s. enteritidis infections in chickens.an elisa was evaluated for the serodiagnosis of fowl typhoid and paratyphoid due to salmonella enteritidis in chickens. the hot phenol: water lipopolysaccharide (lps) extract of salmonella was used as the antigen. chicken serum, eggs and discs impregnated with chicken blood were tested for the presence of antibodies against salmonella factor 'o' 9 antigen. the substrate and chromogen used were hydrogen peroxide and orthophenylenediamine respectively. serological results from the experimentally a ...19921381107
serological response of chickens to infection with salmonella gallinarum-s. pullorum detected by enzyme-linked immunosorbent assay.the serological response to salmonella pullorum and s. gallinarum infection in chickens was studied with an indirect enzyme-linked immunosorbent assay (elisa). in broiler chickens, a more virulent strain of s. pullorum produced a significantly lower serum igg titer than did a less virulent strain. in laying hens, the serum and egg-yolk igg titers were very similar. in chickens infected with s. gallinarum, high igg titers persisted for 30 weeks. in chickens reinfected with this strain, each reinf ...19921385699
is icrf-187 [(+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane] unusually reactive for an imide?the hydrolysis of icrf-187 and two model compounds, 4-methylpiperazine-2,6-dione (4-mp) and 3-methylglutarimide (3-mg), was investigated over the neutral to alkaline ph range at 25 degrees c and an ionic strength of 0.5 (sodium chloride). the purpose of the study was to correlate the influence of molecular changes to the reactivity of these imides. additionally, an improved chromatographic resolution of all the components of the degradation and nmr confirmation of the identity of the degradation ...19921409381
identification of mutations in the pigment cell-specific gene located at the brown locus in mouse.the pigment cell-specific gene, located at the brown (b)-locus in mouse, encodes the protein that determines the type of melanin synthesized. this protein is known as tyrosinase-related protein, but here we tentatively term it b-locus protein to avoid confusions with the related sequence cross-hybridizing to the tyrosinase gene. in order to identify the mutation at the b-locus, we have cloned and characterized the b-locus protein gene of balb/c mouse (b/b, c/c). the gene is about 18 kb long and ...19921409444
molecular bases of tyrosinase-negative oculocutaneous albinism: a single base insertion or a missense point mutation in the tyrosinase gene.we have identified two different mutations in the tyrosinase genes of japanese patients with tyrosinase-negative oculocutaneous albinism (oca). one is a single base insertion in the exon 2 of the tyrosinase gene that shifts the reading frame and introduces a premature termination codon (tga) after the amino acid residue 298 (codon 316). the other is a g to a transition at residue 312, leading to a single amino acid substitution, arginine at position 59 (codon 77) to glutamine. the promoter activ ...19681409445
[classification of erosions of the stomach. results of a meeting of the study group of gastroenterologic pathology of the german society of pathology 23 november 1991 in frankfurt/main]. 19681409452
[congenital complete av block in ss-a and ss-b antibody positive collagenosis of the mother]. 19681409457
interleukin 6: a fibroblast-derived growth inhibitor of human melanoma cells from early but not advanced stages of tumor progression.recently we reported that human dermal fibroblasts, or conditioned media obtained from such cells, affect the growth of human melanoma cells as a direct function of tumor progression: melanoma cells obtained from early-stage (metastatically incompetent) primary lesions were growth inhibited, whereas cells obtained from more advanced (metastatically competent) primary lesions, or metastases, were growth stimulated. ion-exchange and gel-filtration chromatography of fibroblast conditioned medium re ...19921409627
elevated plasma immunoreactive beta-endorphin in anorexia nervosa.basal morning plasma levels of immunoreactive-beta-endorphin (ir-beta-ep), and 17-beta estradiol (e2) were assessed in 25 adolescents with anorexia nervosa (an) in comparison to 24 healthy controls. all subjects were drug free for at least 6 weeks. the mean plasma level of ir-beta-ep was significantly higher (84%) in the an patients when compared with the control subjects. the elevated plasma ir-beta-ep may be relevant to the suppression of appetite, tolerance of fasting, and to the hypothalamic ...19631423337
[phase-contrast and polarization microscopic studies of the myocardium in forensic medical practice].describes the major acute pathologic changes in the myocardiocytes detectable by phase-contrast and polarization microscopy. demonstrates the significance of these changes for a correct diagnosis of sudden coronary death, death from ethanol poisoning or closed injuries of the heart after blunt trauma of the chest.19701455484
[the selection of salmonella gallinarum, salmonella pullorum and escherichia coli in chickens after chloramphenicol administration].the effect of a chloramphenicol administration was examined on the selection of e. coli of the chicken intestinal flora, and of the infectious s. gallinarum and s. pullorum strains. on the other hand, an effort was made to detect the frequency of the resistance transmission of e. coli to above mentioned sensitive salmonella strains. fourteen chicken, 12 infected and 2 negative controls were used. it was found that the enteric e. coli strains became resistant in a week's time. besides, the strain ...19921471974
[natural and experimental infection of rodents (rattus norvegicus) with salmonella gallinarum].thirty five (35) rats (rattus norvegicus) were trapped in the area of four egg producing poultry farms and were examined for salmonella spp., micro-biologically. the samples were taken from liver, spleen and intestinal content. cultures were made directly in macconkey agar, in selenite broth and rappaport vassiliadis at 37 degrees c and 43 degrees c. five strains of s. gallinarum and one strain of salmonella subgroup ii were isolated from the intestinal content of six rats. an experimental study ...19921524579
in-vitro and in-vivo characteristics of tnphoa mutant strains of salmonella serotype gallinarum not invasive for tissue culture cells.insertion mutants of a strain of salmonella serotype gallinarum, the cause of fowl typhoid, were produced with transposon tnphoa. eight mutants were identified as being less invasive in cell culture than the parent strain. neither the parent strain nor the mutants showed mannose-sensitive haemagglutination of various red blood cell species. although two mutants gave mannose-resistant (mr) haemagglutination of red cells of different animal species these mr activities could not be correlated with ...19921613777
a disc elisa for the detection of salmonella group d antibodies in poultry.an elisa using lipopolysaccharide antigens prepared from salmonella gallinarum and s enteritidis was developed for the serological diagnosis of fowl typhoid and s enteritidis infection in poultry. there was good agreement between the results of the elisa and conventional serological tests when samples from naturally infected birds and s enteritidis immunised birds were tested. some cross reactions were observed when serum samples from s typhimurium infected birds were tested by elisa. subsequent ...19921620974
unintentional carbon monoxide-related deaths in the united states, 1979 through 1988.to describe the epidemiology of recent unintentional carbon monoxide poisoning deaths in the united states.19701712865
pediatric hematology and oncology in norway: a brief historical review.before world war ii no real subspecialization occurred in norweigan pediatrics. in the early 1950s hematology and oncology were adopted as fields of special interest by a few norwegian pediatricians. gradually an increasing expansion has taken place, particularly in pediatric oncology, in parallel with the great advances in cancer treatment.20051782111
protein engineering to change thermal stability for food enzymes.in this review we have briefly indicated how the present state of knowledge allows proteins to be mutated to increase or decrease stability. we have discussed experiments on both model proteins and those of relevance to the food industry, and show how hydrophobic forces are a major driving force for folding as well as having a major role in thermostability. we have also indicated the large contribution that hydrogen bonding, electrostatic interactions and, in a less well predicted way, disulphid ...20011783192
cloning and dna sequence analysis of the serc-aroa operon from salmonella gallinarum; evolutionary relationships between the prokaryotic and eukaryotic aroa-encoded enzymes.the serc-aroa operon of salmonella gallinarum was isolated from a gene library using a labelled oligonucleotide probe and by complementation of an aroa escherichia coli strain. the nucleotide sequence of a 2.6 kbp fragment was determined. the predicted amino acid sequence of the aroa gene product was compared to the equivalent sequence from ten other organisms. computer-generated evolutionary trees clearly divide the eleven sequences into four different groups: gram-negative bacteria, gram-posit ...19912045774
immunity to experimental fowl typhoid in chickens induced by a virulence plasmid-cured derivative of salmonella gallinarum.chickens were immunized by two intramuscular inoculations at 1 and 14 days of age with virulence plasmid-cured derivatives of salmonella gallinarum and were challenged 14 days later by oral inoculation of ca. 50 50% lethal doses (ld50) of fully virulent s. gallinarum 9. mortality in the nonimmunized and immunized groups were 36 and 3%, respectively. this difference was highly significant (p less than 0.01). a significant reduction in mortality was also produced following oral challenge with 5,00 ...19902194968
pharmacokinetics and tissue residues of kitasamycin in healthy and diseased broilers.the pharmacokinetics of kitasamycin after intravenous and oral administration in a dose of 300 mg/kg b.wt. was studied in 18 healthy and 18 salmonella gallinarum naturally infected chickens. the tissue residue of the studied antibiotic was estimated in 36 normal chickens when it was given orally for 7 successive days. therapeutic level of kitasamycin was achieved after 15 minutes and persisted for 20-22 hours after its oral administration. higher serum kitasamycin concentrations were recorded in ...19902209453
[myasthenic reaction in polymyositis]. 19562217859
a survey of infectious diseases in wild turkeys (meleagridis gallopavo silvestris) from arkansas.wild turkeys (meleagridis gallopavo silvestris) trapped as part of a relocation program by the arkansas game and fish commission were tested for selected infectious diseases and parasites. the 45 birds were trapped at four locations in pope, scott, and montgomery counties (arkansas, usa). forty-four blood samples for serology, 27 blood smears and 12 fecal samples were collected. of the serum samples tested, 20 of 44 (45%) were positive for pasteurella multocida by enzyme-linked immunosorbent ass ...19902250323
diploidization of bovine oocytes matured in vitro and parthenogenetically activated by electric shock.bovine in vitro matured oocytes were parthenogenetically activated by a single pulse of direct current. suppression of second polar body extrusion by 60 v dc-pulse followed by cytochalasin b treatment or 240 v dc-pulse were used to diploidize parthenogenones. analysis of the cytological events 20 h postactivation clearly documented high efficiency of both diploidization techniques. all oocytes exposed to a single 60 v dc-pulse and then to cytochalasin b for 3 to 6 h were activated and 70% to 88% ...19902257933
proposed revisions to the serological typing system for treponema hyodysenteriae.antisera were prepared in rabbits against seven well-characterized strains of treponema hyodysenteriae of known serotype, and reacted in agarose gel double immunodiffusion tests (agdp) with lipopolysaccharide (lps) extracted from 18 western australian isolates of the organism. eight isolates were provisionally typed by this method, but sera raised against one 'typed' and two 'untypable' local isolates reacted in an unexpected fashion with lps from other local and type strains. serum raised again ...19892492944
neomycin induces high-affinity agonist binding of g-protein-coupled receptors.neomycin, an inositol-phospholipid-binding aminoglycoside antibiotic, is known to interfere with signal transduction mechanisms involving phospholipase c as effector enzyme. in this study, we report that neomycin can also markedly influence agonist binding of g-protein-coupled receptors. in membranes of differentiated human leukemia cells (hl 60 cells), neomycin (0.1-10 mm) was found to induce high-affinity binding of the chemotactic tripeptide, n-formyl-methionylleucylphenylalanine (fmet-leu-ph ...19892556274
[sudden infant death]. 20082588606
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