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[on the problem of in vitro sensitivity of some salmonellae to antimicrobial substances (author's transl)]. 1975124226
letter: immune-complex disease in typhoid fever. 1975124544
the mutagenicity of captan and related fungicides. 1975124818
effect of tilorone treatment on intracellular microbial infections in specific-pathogen-free mice.specific-pathogen-free cd-1 mice were treated orally with the drug tilorone (2,7-bis[2-diethylaminoethoxy]fluoren-9-one hydrochloride) at dosages of 10 or 100 mg per kg of body weight. drug was given 24 h before challenge and then every other day for up to 15 days. growth of sublethal doses of listeria monocytogenes, mycobacterium bovis (bcg montreal), m. tuberculosis h37rv, and salmonella enteritidis in the livers and spleens of intravenously challenged mice was significantly increased compared ...1975125066
effect of oral niridazole treatment on some bacterial infections in mice.treatment of specific-pathogen-free cd-1 mice with oral doses of 10 or 100 mg of niridazole per kg of body weight given 24 h before challenge and then every other day for up to 15 days altered the growth curves for listeria monocytogenes, mycobacterium bovis (bcg montreal), m. tuberculosis h37rv, and salmonella enteritidis seen in the livers and spleens of the treated animals. niridazole in an oral dosage of 10 mg/kg reduced (but did not eliminate) tuberculin hypersensitivity in the mycobacteria ...1975125067
microbiology--waterborne outbreaks. 1975125804
protection against cholera. a bactericidal mechanism on the mucosal surface of the small intestine of mice. 1975126054
chemical structure of lipopolysaccharides and endotoxin immunity.lipopolysaccharides (endotoxins) of gram-negative bacteria consist of 2 components with distinct physico-chemical character: a heteropolysaccharide and a covalently linked lipid, termed lipid a. the chemical structure of lipid a, which represents the toxic center of lipopolysaccharides, is discussed. evidence is presented that lipid a antiserum suppresses the pyrogenic effect of lipid a and lipopolysaccharides in rabbits. the protective power of lipid a antiserum, however, is only expressed in a ...1975126554
use of limulus assay to compare the biological activity of peptidoglycan and endotoxin.the gelation of a lysate prepared from the amebocytes of limulus polyphemus, the horseshoe crab, has been used to detect endotoxin-like material in clinical studies and in "in vitro" experiments. the investigation of blood samples from 54 hospitalized patients suspected of having endotoxemia, revealed a positive limulus test in 14. infections due to gram-positive organisms were not associated with positive assays. these results were in agreement with the observation that living gram-positive mic ...1975126558
the effect of some bacterial products on temperature and sleep in rat.the lipopolysaccharides from p. aeruginosa, s. minnesota and mucopeptide from streptococcus group a injected intravenously into rats induce a dose-dependent changes of temperature. simultaneously, a profound disturbance of sleep occurs. the administration of salicylate, which markedly suppressed the fever does not influence the mucopeptide-caused sleep disturbance. the most prominent change in the sleep pattern is a marked decrease of the total time of paradoxical sleep. the measurement of turno ...1975126560
[protection by oral vaccination of mice with an avirulent live strain of salmonella typhimurium].before determining the quantity of mouse intestinal secretory iga after oral vaccination, we have tried to find the best conditions of immunization with an avirulent s. typhimurium strain given by oral route. the results show the superiority of the live vaccin with respect to the heat-killed one.1975126768
[incidence of salmonellas in the region of the capital of prague in the period from 1952 till 1971 (author's transl)]. 1975126814
[problem of interallelic complementation]. 1975127479
comparison of trimethoprim-sulfamethoxazole and amoxicillin in therapy of chloramphenicol-resistant and chloramphenicol-sensitive typhoid fever.the efficacy of orally administered trimethoprim-sulfamethoxazole was compared with that of oral amoxicillin in therapy of typhoid fever due to both epidemic chloramphenicol-resistant and endemic chloramphenicol-sensitive salmonella typhi. both drug regimens were effective and of comparable value in treatment of chloramphenicol-resistant infections, as measured by duration of fever (124 hr and 115 hr, respectively) and duration of bacteremia (1.0 and 0.4 days, respectively). trimethoprim-sulfame ...1975127815
salmonella typhimurium hfra, a mutant in which adenosine triphosphate can drive amino acid transport but not energy-dependent nicotinamide nucleotide transhydrogenation.in contrast with wild-type salmonella typhimurium lt2, strain hfra did not have atp-driven energy-dependent transhydrogenase activity, although atp-dependent quenching of atebrin fluorescence was normal. respiration-dependent and energy-independent transhydrogenase, and ca2+-activated atpase (adenosine triphosphatase) activities were similar in both strains. purified atpases from the two strains had similar specific activities, similar subunit polypeptides, and were equally effective in restorin ...1975128357
[salmonella-enteritis among users of a communal dining room (author's transl)]. 1975128721
[genetic bases for the selection of microorganisms using analogs].the main mechanisms are considered for biosynthesis processes regulation by means of repression and inhibition with final products. on the basis of these mechanisms the state and prospects of the directed alteration of various stages in regulating the synthesis of primary and secondary metabolites, using breeding selection of mutants resistant to analogues are discussed. the main regularities are presented for using analogues of primary metabolites in the breeding strains with overproduction of ...1975128859
clinical aspects of hepatosplenic schistosomiasis: a contrast with cirrhosis.the clinical picture of liver disease in endemic areas of schistosomiasis mansoni differs in many ways from that observed in alcoholic and other types of cirrhosis. in hepatosplenic schistosomiasis there is predominance of the clinical manifestations of portal hypertension, e.g., bleeding esophageal varices, while ascites, jaundice, and hepatic precoma or coma are much less common. ammonia tolerance is usually normal and helps explain the low mortality rate during bleeding. of special interest i ...1975128911
mechanisms of siderophore iron transport in enteric bacteria.uptake of 55fe- and 3h-labeled siderophores and their chronic analogues have been studied in salmonella typhimurium lt-2 and escherichia coli k-12. in s. typhimurium lt-2, at least two different mechanisms for siderophore iron transport may be operative. uptake of 55fe- and 3h-labeled ferrichrome and kinetically inert lambda-cis-chromic [3h]deferriferrichrome by the s. typhimurium lt-2 enb7 mutant, which is defective in the production of its native siderophore, enterobactin, appears to occur by ...1976131124
[incidence of human salmonellosis and frequency of salmonellae in waters of the area of braunschweig during 21 years (author's transl)]. 1975131269
[regional development of salmonelloses (author's transl)]. 1975131271
[antibiotic sensitivity of the salmonella isolated from children in krasnodar].the results of the comparative study of antibiotic sensitivity of 138 salmonella strains isolated from children patients in krasnodar are presented. the isolates belonged to 9 serological types and were classified into 4 serogroups. salmonella fo group b prevailed. the highest sensitivity was found with respect to neomycin. strains sensitive to levomycetin and streptomycin were rare. single strains were sensitive to all antibiotics tested. a tendency to polyresistance in ever increasing numbers ...1976132137
mutagenicity assays on fluorescent whitening agents using microorganisms.six fluorescent whitening agents (fwas) have been re-examined for their activity as inducers of cytoplasmic petite mutants and mitotic gene conversion in diploid yeast saccharomyces cerebisiae and reversion from auxotrophy to prototrophy in neurospora crassa, escherichia coli and salmonella typhimurium. the results provide no indication that the fwas examinded produce mutagenic changes or any other alterations in the gene material. in a recent re-examination with salmonella using the method of a ...1975132347
mg2+, ca2+-dependent adenosine triphosphatase as receptor for divalent cations in bacterial sensing.the mg2+, ca2+-dependent adenosine triphosphatase responsible for interconversion of the energized membrane state to adenosine triphosphate is the receptor for divalent metal ions in bacterial chemotaxis. the receptors controlling bacterial behavior show a common pattern of dual functions.1976132702
[ecological relations of salmonella en chile]. 1976132948
role of adenosine deaminase in lymphocyte proliferation.activity of adenosine deaminase (ada), an enzyme known to be deficient in some patients with severe combined immunodeficiency, increased three-fold within a 24-hour exposure of human peripheral blood lymphocytes to phytohaemagglutinin (pha) in culture. this increase took place before the onset of dna synthesis. increased levels of ada activity were also observed in lymphocytes incubated with pokeweed mitogen (pwm) for 60 hr. dna synthesis induced by pha, pwm or mixed lymphocyte cultures (mlc) wa ...1976133008
microbiology--waterborne outbreaks. 1976133251
[specific prophylaxis of colibacillosis and salmonellosis in lambs and piglets]. 1976133510
a transmissible plasmid determining lactose fermentation and multiple antibiotic resistance in a strain of klebsiella pneumoniae.in a wild strain of klebsiella pneumoniae the plasmid that determined lactose fermentation also determined resistance to chloramphenicol, ampicillin, tetracyclines, streptomycin, spectinomycin, and sulphonamides. the plasmid transferred at a very low rate to escherichia coli k12 and salmonella typhi. by implanting other transfer factors in the strain the rate of transfer and the recipient range were increased. plasmid transfer from the modified strain to salm. typhimurium and salm. gallinarum wa ...1976134162
atmospheric mutagens. i. sulfur oxides and nitrogen oxides. 1976134284
[samonella (author's transl)]. 1976134323
[food hygiene from the point of view of the public health department (author's transl)]. 1976134334
[quantitative method of isolating salmonella from soil using liquid nutrient media]. 1976134934
[circulating salmonella serotypes isolated in the territory served by the sanitary-antiepidemic center of covasna county].during the 1967-1973 period, the authors followed up the circulation of various salmonella serotypes and found new serotypes linked to the particular epidemiologic aspects recorded within a small district, without highly populated centers. the results showed a steady increase in the strains isolated during the last 3--4 years. among the total 2103 strains isolated, s. panama, s. typhimurium and s. bredeney were predominant. the number of serotypes isolated varied between 10 (1968--1969) and 16 ( ...1976135331
mutagenicity of beta-oxidized n,n,-di-n-propylnitrosamine derivatives in s. typhimurium mediated by rat and hamster tissues.the relative abilities of liver, kidney and lung fractions from untreated or phenobarbitone-pretreated rats and hamsters to convert n,n-di-n-propylnitrosamine and several beta-oxidized synthetic putative intermediates into mutagens was quantitatively compared in a tissue-mediated mutagenicity assay with s. typhimurium ta 1530 in vitro. with one exception, namely, n,n-di(2-acetoxy-n-propyl)nitrosamine, liver was the most active tissue from hamsters; in rats also, only liver fractions were able to ...1976136104
[genetic characteristics of the determinant controlling the ability to ferment sucrose in atypical strains of s. newport]. 1976136136
[phage-typing of typhoid cultures and results of use of this method in anti-epidemic practice in the azerbaijan ssr].this work was aimed at the study of the phage-type pattern of the causative agents of typhoid fever isolated in the azerbaijan ssr in 1960-1973. as revealed, the following 26 phage-types circulated in azerbaijan during the period under study: a, b1, b2, b3, c1, c4, c5, d1, d2, d4, d8, e1, e2, e3, e5, f1, f2, i1, m1n, t, 28, 38, 39, 40 and 46. the most widespread were phage-types a (22.86%), e1 (13.96%), f1 (9.74%), f2 (6.70%), and 28 (5.71%) constituting over half of the typed typhoid strains. s ...1976136162
[blood groups of the abo system of chronic carriers of typhoid bacteria and typhoid patients in uzbekistan].blood groups of the abo system were studied in 186 chronic carriers of typhoid bacilli and in 392 patients with typhoid fever from various districts of the uzbek ssr. in comparison with control (healthy persons), carriers displayed a higher percentage of persons with a (ii) blood group (50.88 and 42.64 against 37.51 and 32.13 in control) and a lesser percentage of persons with the o (i) blood group (21.05 and 22.48 against 32.93 and 32.07 in control). these data demonstrated that predisposition ...1976136163
in vitro phagocytosis of candida albicans by peripheral polymorphonuclear neutrophils of patients with recurrent infections:case reports of serum-dependent abnormalities.the "in vitro" phagocytosis of c. albicans by peripheral polymorphonuclear neutrophils (pmn) of 25 healthy subjects and of 27 patients with recurrent infections was performed in autologous serum and in normal pooled ab serum. in ab serum pmn of the patients phagocytosed c. albicans significantly better than pmn of healthy subjects. in 9 out of 27 patients the phagocytosis of c. albicans by the patient's pmn was markedly lower in autologous serum than in ab serum. four patients with extreme serum ...1976136278
[the examination of lysogenic properties of salmonella typhimurium strains; utilization for further differentiation of phage types (author's transl)]. 1976136307
mutagenicity of streptozotocin and several other nitrosourea compounds in salmonella typhimurium.the following nitrosourea compounds were compared for their ability to induce mutation (to histidine independence) in the histidine-requiring auxotroph salmonella typhimurium his g46: mnu, streptozotocin (sz, streptozocin) and its analogs sza1 and sza2, and the antitumor drugs bcnu, ccnu and dcnu. at equitoxic doses sz, sza1, sza2 and mnu were almost equally mutagenic causing 150, 42, 140 and 170 mutants/106 survivors at 20% lethal dose (id20) although, on a wieght basis, sz was the most mutagen ...1976138082
association of salmonella mutants with germ-free rats: characterization of the reverse mutational response to 2-nitrofluorene.salmonella typhimurium strain ta1538 described by ames, in association with otherwise germ-free rats, colonizes the gastrointestinal tract. the revertants enumerated in the feces of each of these rats varies in a coordinated manner in relation to the day on which the measurement is made. in response to the oral ingestion of a single dose of 2-nitrofluorene, the concentration of revertants in the feces increases and then returns essentially to control values within 6 days. when these rats are cha ...1976138083
mammalian host- and fluid-mediated mutagenicity assays of captan and streptozotocin in salmonella typhimurium.the mutagenicity of captan and of streptozotocin was tested in vivo by reversion of hisg46 base-pair substitution histidine auxotrophs of salmonella typhimurium in the peritoneal cavity or in blood, plasma or urine of rats or mice. genetic response was determined by the frequency of revertants (quantitative test) or by the number of revertants per plate (semiquantitative test). in quantitative hma captan gave negative results following 3 hourly 500 mg/kg s.c. doses or 1000 mg/kg oral dose in mic ...1977138085
mutation induction by the antischistosomal drug f30066 in various test systems.the genetic activity of furapromidium (f30066), an antischistosomal drug, was studied in salmonella typhimurium, saccharomyces cerevisiae, neurospora crassa and cultured chinese hamster cells. the results show that f30066 induces gene mutations in s. typhimurium, n. crassa and chinese hamster cells. this compound also causes gene conversions in s. cerevisiae.1977138086
[typhoid bacilli resistant to chloramphenicol and multiresistant to antibiotics isolated at the beginning of 1971].the sensitivity of chloramphenicol (c) of 286 s. typhi strains, isolated during the last 15 years in moldavia, was tested. the minimum inhibitory concentration (mic) of c with regard to most of the strains ranged between 1.5 and 3 mcg/ml. the following stains were identified: strain w isolated from the feces of a carrier in 1971, with a ackssut-cl2hg resistance spectrum transferable to e. coli k12(mic of c less than or equal to 200 mcg/ml), 2 strains (phage type a and c1, isolated from patients, ...1976138926
single-strand nicking of dna in vitro by neocarzinostatin and its possible relationship to the mechanism of drug action.neocarzinostatin, a protein antibiotic with anti-tumor activity was found to place single-strand scissions in dna in an in vitro reaction. the drug's cutting activity was strongly dependent on the presence of 2-mercaptoethanol or dithiothreitol but some cutting did take place in the absence of reducing agent at very high drug levels and prolonged incubation. the requirement for reducing agents could not be replaced with nad+, fad, nadh or h2o2 and the strand-scission reaction was not affected by ...1977139167
antimicrobial resistance and r factors in salmonella isolated from humans and animals in georgia and south carolina.three hundred and five strains of salmonella isolated from humans and 152 strains isolated from animals in georgia and south carolina during 1973 were examined for resistance to 14 antimicrobial agents. s typhimurium was the most frequently isolated serotype (30% of human isolates and 13% of animal isolates). the overall incidence of antimicrobial resistance was 16% in human starins and 21% in animal strains. the most commonly found resistance were to streptomycin (11% in human strains and 16% i ...1977139683
[economic effectiveness of antibiotics in pullorum disease-fowl typhoid in poultry]. 1976139739
[salmonella carrier state in sparrows]. 1976139740
[salmonellosis in hospitalized children]. 1977139902
[the first finding of salmonella bilthowen from human material in the cssr, district zd'ár n. sáz (author's transl)]. 1977141339
[a case of typhoid in a boy acquired by drinking brook water polluted by sewage (author's transl)]. 1977142222
[evolution of mouse intestinal and blood immunoglobulins after oral route vaccination].the authors have studied the mice immunoglobulins level after vaccination by oral route with a killed-pathogenic strain of salmonella typhimurium and an avirulent mutant of the same bacteria. the obtained results show an increase of the intestinal iga and igg1 levels and a slighter one of sera igg between the 10 th and 30 th day following immunization. no correlation was observed concerning the igm, igg and iga levels and the mice protection against a challenge of pathogenic bacteria.1977142559
[the effect and reported side effects of clioquinol]. 1977142871
the genetic properties of beta-propiolactone. 1977142920
the in vitro drug resistance of salmonella dublin isolated from cattle.the resistance of salmonella dublin to eight antibacterial drugs was assessed under diagnostic laboratory conditions. two techniques were used consecutively and the differences in the results are described. strains of s. dublin isolated from either calves, adult cattle or abortion material showed no differences in resistance for either of the techniques, though differences between the two techniques were found.1977143494
inhibition of na+, k+-adenosinetriphosphatase by endotoxin: a possible mechanism for endotoxin-induced cholestasis.cholestatic jaundice is one complication of nonhepatic gram-negative bacterial infection. the endotoxin of escherichia coli has been reported to cause cholestasis by inhibiting the bile salt-independent fraction (bsif) of bile in the perfused rat liver. accordingly, the effects of lipopolysaccharides (lps) of e. coli and salmonella enteritidis on the na+, k+-adenosinetriphosphatase (atpase) in canalicular-enriched plasma membranes of rate liver were examined. at 20 microgram/ml, both endotoxins ...1977143499
[use of bactorodencide in rodent control]. 1977143755
actual status of mutageneity testing with the host-mediated assay. 1977143925
[birds as carriers of salmonella (author's transl)]. 1977144257
use of transferrin-iron enterobactin complexes as the source of iron by serum-exposed bacteria.two smooth and six rough strains of salmonella typhimurium with progressively smaller amounts of sugar and protein in their outer membrane were tested for degree of virulence in normal and iron-injected mice and for ability to acquire iron in mammalian sera. the rate of mortality showed that bacterial virulence for mice was lowered with progressive decrease of outer-membrane sugar and protein. iron injections increased the rate of mortality in mice infected either with smooth strains or with sup ...1977144704
[experience on incidence of salmonellosis in air trips to and from the canary islands (author's transl)]. 1977144880
[simplified diagnostic scheme for enterobacteriaceae].after testing 18 experimental variants against 40 reference strains belonging to different enterovacteriaceae groups, the authors chose a multitest medium that permits concomitant testing of mobility, indol, lysinedecarboxylase and phenylalanine deaminase (milp). in this medium, the reactions of 3734 strains belonging to the genera escherichia, shigella. salmonella, citrobacter, klebsiella, enterobacter, serratia. proteus and providencia were concordant with the reactions in individual test medi ...1977144994
[new methods for clearing salmonella excretors (author's transl)]. 1977145559
siderophores: diverse roles in microbial and human physiology.siderophores, defined as high affinity iron(iii) ion transport agents, and their cognate membrane-bound receptor complexes, occur in the enteric bacteria escherichia coli and salmonella typhimurium. the total system is tightly regulated by iron repression. the transport properties of the specific siderophores enterobactin and ferrichrome (which is not made by these particular enteric bacteria) have been examined in detail. in e. coli the outer membrane receptor for ferrichrome is programmed by t ...1976145937
tryptophan metabolism in relation to amino acid alterations during typhoid fever.with the onset of fever in volunteers exposed to virulent salmonella typhii as part of a vaccine evaluation study, urinary excretion of kynurenine, acetyl-kynurenine and o-amino-hippurate significantly increased by n-methylnicotinamide decreased. serum tryptophan concentration at that time was 116% of control in contrast to total serum amino acid values at 83% of control. a 3 gram oral tryptophan load given during illness further increased serum tryptophan concentration to 186% of control and en ...1975146413
[mutagenicity of the metabolites of the epoxide-diol pathway of safrole and its analogs. study on salmonella typhimurium].mutagenicity of the metabolites of the expoxide-diol pathway of safrole and analogues was studied on ames' strains with ames' method. safrole, eugenol, eugenolmethylether, estragol, allylbenzene and 1'-hydroxysafrole, are not mutagen on ta 1535, ta 100 (point mutation) and ta 1537, ta 1538, ta 98 (frameshift mutations) without activation system. the corresponding epoxides that we have synthetized, are mutagens and inducers of point mutation in ta 1535 and ta 100. dose-effect curves show differen ...1977146546
[detection of pathogenic enterobacteriaceae in seawater].as a result of investigations carried out in the littoral sea waters (a total of 114 sea water samples were analyzed) there were isolated 226 strains of salmonellae referred to 9 serological types, this constituting 35% of the positive samples. as revealed, salmonella distribution in sea water depended on the site of outflow of sewage, and also on the unfavourable influence of rivers inflowing to the littoral part of the sea.1978146990
[immunosuppressive activity of several drugs and their effect on antibody formation in pullorum disease].furazolidon given alone or in combination with chloramphenicol, with spectinomycin, with gentamycin or with sodium arsenilate as well as chlorpyrazine, applied alone, suppress the clinical manifestation of pullorum disease in birds both in the experimental and in the spontaneous outbreak of the disease. these medicinal drugs lower the production of agglutinins in birds--mostly the combination furazolidon+chloramphenicol, followed by furazolidon+sodium arsenilate. the same combinations do not pro ...1977147557
the immunological relationship between filtrable agent, salmonella and murine leukosis.salmonella typhimurium was invariably isolated from our j strain murine leukosis. immunization of d103 mice with either inactivated salmonella typhimurium or the cell-free extract of leukosis inhibited the transplantation of leukosis. the adoptive immunization of d103 mice with spleen cells of strong a mice immunized with either salmonella or the cell-free extract of leukosis inhibited the transplantation of leukosis. the addition of either salmonella or the cell-free extract of leukosis inhibit ...1977147604
[laboratory effectiveness in bacteriological health research for the presence of salmonellae]. 1978147805
[concentration of antibiotics in long term embolized kidneys (author's transl)].in 7 dogs renal arterial embolization was performed using seldinger technique and inflatable swan ganz balloon catheter by injection of methyl methacrylate/butyl 2 cyano acrylat. six months later tissue concentration of cefazolin was measured in the embolized and kontralateral kidneys and in serum two hours after a short infusion of 1 g of cefazolin. the concentrations in serum and homogenized kidney tissue were determined by means of the agar well diffusion method. angiography studies showed no ...1978147821
siderophore production by vibrio cholerae.vibrio cholerae produces a phenolate-type siderophore that stimulates growth of the organism in low-iron medium. this compound is similar, but not identical, to enterochelin, the siderophore produced by salmonella and escherichia coli.1978149768
incidences of simple and transferable drug resistance in escherichia coli and salmonella isolated from various foods: identification of a r plasmid in s. saint-paul.a study of 1,043 strains of e. coli and 22 strains of salmonella isolated from various foods in eastern france between the dates of june 1974 and december 1976 showed that 164 (15.6%) of e. coli and nine salmonella were resistant to one or several drugs. only 18 of the 83 resistant e. coli strains were able to transfer their resistance to tetracycline and some other drug resistance to e. coli k12 in vitro. a conjugative r plasmid has been identified by transfer experiments, incompatibility testi ...1978150244
mutagenicity of vinyl chloride monomer. 1977150257
transport functions of the outer membrane of enteric bacteria. 1978150390
constitutive expression of the iron-enterochelin and ferrichrome uptake systems in a mutant strain of salmonella typhimurium.two high-affinity iron uptake systems are known in salmonella typhimurium, one utilizing iron-enterochelin and the other utilizing ferrichrome. it has been shown previously that expression of several elements of the iron-enterochelin uptake system are regulated by the iron content of the medium, with growth in high-iron medium resulting in repression of enzymes of enterochelin synthesis and degradation and of the ability of whole cells to take up iron-enterochelin. in this study we describe a mu ...1978151097
n-(5-amino-1-ribosyl-4-imidazolylcarbonyl)-l-aspartic acid 5'-phosphate synthetase. 1978151181
mutagenicity testing of benomyl, methyl-2-benzimidazole carbamate, streptozotocin and n-methyl-n'-nitro-n-nitrosoguanidine in salmonella typhimurium in vitro and in rodent host-mediated assays.the fungicide benomyl and its commercial preparations fundazol 50wp and benlate 50wp and the benomyl metabolite methyl-2-benzimidazole carbamate and its commercial preparation mbc 50wp were tested for mutagenicity in in vitro spot tests, in microsomal plate assay, in liquid-culture treatments, or in rodent host-mediated assay. the base-pair substitution salmonella typhimurium mutant hisg46 and the hisg46-bearing uvrb excision-repair-deficient mutants ta100, ta1530, ta1535 or ta1950 were used as ...1978151228
[distribution of lysotypes of salmonella typhi, s. paratyphi b and s. typhimurium in north-rhine westphalia during 1966 to 1975 (author's transl)]. 1978151829
comparative mutagenicity and toxic effects of 2,5,2',5'-tetrachlorobiphenyl and its metabolites in bacterial and mammalian test systems.the possible toxicological properties of 2,5,2',5'-tetrachlorobiphenyl (tcb), 4-hydroxy-2,5,2',5'-tetrachlorobiphenyl (tcb-oh), and 2,5,2',5'-tetrachlorobiphenyl-3,4-oxide (tcb-oxide) were evaluated in three bioassay systems. incubation of rat hepatocyte plasma membranes with 50 microgram/ml of tcb-oh decreased the activity of mg2+-atpase by approximately 90%, whereas approximately half of the enzyme activity remained after the tcb or tcb-oxide treatment. all three compounds were found to be ina ...1978151904
[enterotoxins of gramnegative intestinal bacteria (author's transl)]. 1978152163
bacterial motility and chemotaxis: the molecular biology of a behavioral system. 1978152692
the mutagenicity of dichloroacetaldehyde.dichloroacetaldehyde, a presumed metabolite of the insecticides dichlorvos and trichlorphon, is mutagenic in the salmonella/microsome test. its mutagenic potency is higher than that of the established mutagen dichlorvos. it is possible that the bacterial mutagenicity test only or mainly detects the effect of methylation by dichlorvos.1978153665
[salmonella in hospital food handlers]. 1978153757
[immunologic reactions in vitro to abnormal forms of salmonella typhimurium induced in the presence of fosfomycin]. 1978154074
[detection of salmonella typhi carriers in mexico]. 1979154338
1,3,5-tris(n,n',n''-2,3-dihydroxybenzoyl)amino-methylbenzene, a synthetic iron chelator related to enterobactin. 1979154575
[rearing of germfree rabbits and establishment of an spf rabbit colony].baby rabbits hysterectomy-derived from conventional japanese white rabbits were reared under aseptic condition by feeding with 4 types of artificial diets. rabbit milk for the artificial diet was obtained from conventional dams at 7--25 days after delivery. the artificial diets was given by stomach tube twice a day. the total volumes of diet given (ml per day) were y = 2.3x + a (1 to approximately 14 days of age), y = 32.2 + a (l5 to approximately 25 days of age), or y = (32.2 + a) - 37.5 (x - 2 ...1979155008
[rearing of germfree guinea pigs and establishment of an spf guinea pig colony].new born guinea pigs of hartley strain derived by hysterectomy were fed commercial pellets, cow's milk, egg yolk and vitamin mixture since 0 days of age, when they were kept at 31 +/- 1 degrees c. out of 33 animals, 30 were reared for 40 days under aseptic state and they were transfered to a barrierred facility to establish an spf colony free from bordetella bronchiseptica, streptococcus zooepidemicus (animal c), salmonella spp., tyzzer's organisms, mycoplasma spp., reo 3 virus, sendai virus, ei ...1979155009
literature survey of bacterial, fungal, and drosophila assay systems used in the evaluation of selected chemical compounds for mutagenic activity.literature reports were surveyed, with results noted from experiments in seven nonmammalian assay systems used for the detection of mutagenicity or other related genetic effects. a comparison was made of the activities of 54 selected noncarcinogens, procarcinogens, and ultimate carcinogens as revealed by these test systems. of the compounds tested, 49 (91%) were active in one or more of the assays, and 42 (78%) were positive in at least one system without having to be metabolically activated. in ...1979155170
the value of plasmid studies in the epidemiology of infections due to drug-resistant salmonella wien.since 1969 strains of salmonella wien that are resistant to multiple antibacterial drugs have caused widespread epidemics of enteritis in europe and north africa. of 113 british strains examined between january 1970 and january 1977, 67 were multi-resistant. these strains and 22 strains from six other countries were examined to determine their plasmid content. two plasmids were found in the vast majority of strains: an fime factor, conferring resistance to ampicillin, chloramphenicol, kanamycin, ...1979155714
reversible translocation of antibiotic resistance determinants in salmonella ordonez.salmonella ordonez (bm 2000) codes for kanamycin (km, apha), ampicillin (ap), streptomycin (smsp:aada and sm:aphc), chloramphenicol (cm), tetracycline (tc) and sulfonamide (su) resistances and for production of colicin ib (cib). genetical analysis by incompatibility testing, conjugation, transformation and physical studies using electron microscopy, agarose gel electrophoresis, led us to associate the km and cib characters to a 98.7 kilobase (kb) inci1 plasmid (pip565), and the sm (aphc) and su ...1979155772
[polyresistance to antibiotics in s. typhimurium isolated in baku]. 1979156001
forward mutation assays using bacteria and 8-azaguanine. 1978156116
[structural investigations on lipopolysaccharides of mutants s sf 1111 and r 595 sf 1167 of salmonella minnesota (author's transl)].the lipolysaccharides of two mutants of salmonella minnesota with known chemical structure were investigated by x-ray methods. both thickness of the lipopolysaccharide layer and arrangement of the molecular components could be estimated. using these informations a space-filling model of the structure was built.1979156467
changes in the immunoglobulin levels of the mouse gut and serum during conventionalisation and following administration of salmonella typhimurium.increasess in all immunoglobulin classes, except igm, were observed in the sera of specific pathogen-free (spf) mice beginning 10 days after their removal from barrier conditions. concentrations of serum immunoglobulins, comparable with those of conventional mice, were obtained in these animals between 21 and 35 days. following the removal of germ-free mice from their sterile isolaters, their intestinal iga levels increased over 35 days to attain levels found in conventional animals. a marked in ...1978156538
[inhibitory action of some bacterial exoproteases in colicines of enterobacteria (author's transl)]. 1979156592
[investigation of the relationship of r-plasmides to the change of the phage type of salmonella strains isolated from typhoid and paratyphoid carriers (author's transl)]. 1979156595
enterochelin (enterobactin): virulence factor for salmonella typhimurium.the ability of salmonella typhimurium to synthesize enterochelin (enterobactin; ent) affects its capacity to grow both in vivo and in vitro. an ent mutant (96-1), blocked in the conversion of chorismate to 2,3-dihydroxybenzoate, was derived from sr-11, a strain of high mouse virulence. this mutant was unchanged in the other characteristics tested: colonial, biochemical, antigenic, and cellular. in contrast to sr-11, growth of this mutant in complement-inactivated human serum was strongly inhibit ...1979156695
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