Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| diagnosis and management of angina pectoris. | 2003 | 187369 | |
| the functional relationship between polymerization and catalytic activity of beef liver glutamate dehydrogenase. ii. experiment. | 1976 | 187756 | |
| fumarate reduction in proteus mirabilis. | 1. proteus mirabilis formed fumarate reductase under anaerobic growth conditions. the formation of this reductase was repressed under conditions of growth during which electron transport to oxygen or to nitrate is possible. in two of three tested chlorate-resistant mutant strains of the wild type, fumarate reductase appeared to be affected. 2. cytoplasmic membrane suspensions isolated from anaerobically grown p. mirabilis oxidized formate and nadh with oxygen and with fumarate, too. 3. spectral ... | 1976 | 189721 |
| rat adrenocortical dynamics. | 1. the dynamics of the adrenocortical response to adrenocorticotrophic hormone (acth) was studied in anaesthetized, acutely hypophysectomized male rats. 2. acth test-signals were applied either in a jugular vein ('intact infused preparation') or in the aorta through the coeliac artery with the aorta ligated below this artery ('isolated in situ perfused preparation'). the adrenocortical responses were measured directly in samples serially taken from the left adrenal vein. 3. tested acth signals w ... | 1977 | 191596 |
| autoradiographic localization of prolactin receptors in 7,12-dimethylbnez[a]anthracene-induced rat mammary carcinoma. | prolactin receptors were localized by autoradiography in 7,12-dimethylbenz[a]anthracene (dmba)-induced mammary tumors from rats by incubation of tumor slices with [125i]ovine prolactin. specific prolactin binding was confined to tumor cells, and nonspecific binding was present in alveolar spaces and connective tissue. in some tumors, all cells contained receptors; in others, up to one-half the cells remained unlabeled. these results suggested that variation in receptor content in dmba-induced ma ... | 1977 | 191627 |
| intrahepatic arterial infusion of combination of mitomycin-c and 5-fluorouracil in treatment of primary and metastatic liver carcinoma. | improvement in drug response and reduction of toxicity were observed after continuous intrahepatic arterial infusion of mytomycin-c (mmc) and 5-fluorouracil (5-fu) in 15 of 26 patients with primary or metastatic carcinoma of the liver. serum bilirubin values of 10 mg/100 ml absence of ascites, extreme cachexia and impending hepatic failure were used as the criteria for admission of these patients into the study. the patients were given mmc in a dose of 0.08 mg/kg on day 1,5-fu in a dose of 8-10 ... | 1992 | 192431 |
| comparison of the effects of mecillinam and 6-aminopenicillanic acid on proteus mirabilis, escherichia coli, and staphylococcus aureus. | single strains of proteus mirabilis, escherichia coli, and staphylococcus aureus were grown on filter membranes placed on agar containing concentration series of mecillinam (fl 1060), 6-aminopenicillanic acid (6-apa), or ampicillin. p. mirabilis and e. coli were also exposed to combinations of mecillinam or 6-apa with ampicillin. colony-forming units were counted, and cells were examined by interference phase-contrast and transmission electron microscopy. mecillinam and 6-apa were very effective ... | 1977 | 193439 |
| polymyxins as inhibitors of polyclonal b-cell activators in murine lymphocyte cultures. | the polymyxin antibiotics polymyxin b sulfate and colistin methane sulfonate were examined for their ability to inhibit responses to the polyclonal b-cell activators (pba) bacterial lipopolysaccharide (lps), dextran sulfate (ds), pneumococcal polysaccharide (siii), and purified protein derivative of tuberculin (ppd) in spleen cell cultures. polymyxin concentrations of 1 and 10 microng/ml significantly inhibited both the deoxyribonucleic acid synthetic and polyclonal antibody responses stimulated ... | 2003 | 193787 |
| pivmecillinam in urinary tract infections: a correlation of urinary bactericidal activity with clinical efficacy. | 1977 | 193813 | |
| occupational asthma caused by low molecular weight chemical agents. | 2003 | 194937 | |
| subcellular distribution of steroids in rat adrenocortical tissue after incubation in vitro [proceedings]. | 1977 | 194992 | |
| elimination of proteus mirabilis 51cr endotoxin from the liver in rats. | using isotope methods, elimination of the endotoxin of proteus mirabilis labeled with chromium (crepm) from the liver of rats was studied. the following studies were carried out: intravital exploration of the liver with a scintillation probe, measurements of radioactivity of organs and excreted urine and stools, scrintigraphy of the liver, binding of crepm by subcellular fractions of hepatocytes, and the influence of selected drugs (polymyxin and hydrocortisone) on elimination of crepm from the ... | 1977 | 195551 |
| factors influencing the apparent molecular weight of collagenase produced by human-skin explants. | 1977 | 195813 | |
| adenosine 3',5'-monophosphate in mycobacterium phlei and mycobacterium tuberculosis h37ra. | adenosine 3',5'-monophosphate (camp) is present in slow growing as well as fast growing mycobacteria. apparently there does not seem to be any direct relationship between either intra- or extracellular camp content with the growth rate of bacilli. as compared to that of e. coli grown on a similar energy source, camp content is much higher in mycobacteria. camp content inside the cells remains unaltered throughout the growth period and this may be due to lack of complete utilization of the major ... | 1976 | 196160 |
| detection of precursors of quinolinic acid in escherichia coli. | a technique is described which allows the detection of precursors of quinolinic acid produced by escherichia coli, independent of a bioassay. this is based on a double autoradiogram utilizing radioactive aspartic acid and fructose-1,6-diphosphate (as a source of dihydroxyacetone phosphate). six radioactive spots are derived from aspartic acid and four are derived from fructose-1,6-diphosphate. the latter four spots correspond to four of the former spots in migration in each of two solvent system ... | 1976 | 196161 |
| cutaneous abscesses. anaerobic and aerobic bacteriology and outpatient management. | specimens from 135 cutaneous abscesses in outpatients were cultured anaerobically and aerobically. of these, 4% were sterile and 29% yielded pure cultures, predominantly of staphylococcus aureus. aerobic species were isolated from all anatomic areas. anaerobes were found with a frequency comparable to aerobes in all nonperineal areas except the hand. in contrast, abscesses in the perineal region contained a greater variety and frequency of anaerobes. only two patients were febrile. all abscesses ... | 1977 | 196534 |
| [diurnal rhythm of cell proliferation at the late stages of precancerous changes in the liver induced by ortho-aminoazo-toluene]. | orthoaminoazotoluol was administered to mice for a period of nine months. circadian rhythms of mitotic activity and the number of the dna-synthesizing cells were determined by autoradiography (with the use of 3h-thymidine) at the second (adenomatous nodes) and the third (primary hepatoma) stages of carcinogenesis in the developing tumours and the surrounding liver parenchyma. the listed structures proved to have a single-peak rhythm of mitotic activity with the maximum of mitoses at 4-7 a. m.; t ... | 1994 | 196705 |
| the relationship of time-dose fractionation factors to complications in the treatment of pituitary tumors by irradiation. | 1994 | 197051 | |
| phosphorylative and functional modifications of nucleoplasmic rna polymerase ii by homologous adenosine 3':5'-monophosphate-dependent protein kinase from calf thymus and by heterologous phosphatase. | 1977 | 197104 | |
| polymorphonuclear leukocyte bactericidal activity and oxidative metabolism during glutathione peroxidase deficiency. | glutathione peroxidase (gpx) deficiency has been proposed as a cause of some instances of chronic granulomatous disease (cgd). gpx activity varies greatly among species, and specific deficiency of this selenium-dependent enzyme can be produced by dietary selenium deficiency in rats. bactericidal activity of polymorphonuclear (pmn) leukocytes from normal rats, humans, and guinea pigs (gpx high, intermediate, and nearly absent, respectively), selenium-deficient rats (gpx absent), and a patient wit ... | 1977 | 198376 |
| [effectiveness of the use of diphenin in insuloma]. | 2003 | 201043 | |
| [case of carotid chemodectoma]. | 2003 | 201051 | |
| [hospitalization of the elderly]. | 2003 | 201113 | |
| enzyme histochemistry of cultured ovarian cells. ii. histochemistry of porcine theca interna cells in tissue culture. | by means of histochemical technique the activities of delta53beta-, 17beta-, 20alpha-hydroxysteroid dehydrogenases and glucose-6-phosphate dehydrogenase, as well as alkaline and acid phosphatase were investigated in monolayer cultures of theca interna cells, isolated from preovulatory porcine ovarian follicles. it was found that theca interna cells exhibited high and constant activity of delta53beta-hydroxysteroid dehydrogenase and g6p-dh, whereas activities of both 17beta- and 20alpha-hydroxyst ... | 1976 | 201115 |
| epstein-barr virus and cytomegalovirus antibodies in infectious mononucleosis. | a method has been evolved for the demonstration of epstein-barr virus (ebv) and cytomegalovirus (cmv) infection in 83 cases of infectious mononucleosis. serum samples were tested for ebv igm, anti-vca igg, anti-ebna, cmv igm and cmv igg antibodies. an acute-phase sample (or samples) and a convalescence sample were examined in each case, and in 44 cases an additional samples was examined 5-12 months after the illness. since the different antibodies showed characteristic differences in both titre ... | 1977 | 201153 |
| relationship between the reduction of oxygen, artificial acceptors and cytochrome p-450 by nadph--cytochrome c reductase. | the interaction of nadph--cytochrome c reductase with oxygen, artificial acceptors and cytochrome p-450 was studied. the generation of superoxide anion radicals (o2-.) from the oxidation of adrenaline to adrenochrome catalysed by nadph--cytochrome c reductase proceeds independently of the interaction of the enzyme with the artificial anaerobic acceptors cytochrome c or 2,6-dichlorophenol-indophenol. propyl 3,4,5-trihydroxybenzoate inhibited competitively the adrenaline oxidation by isolated nadp ... | 1977 | 202259 |
| human leukocyte migration inhibitory factor (lif). iv. 3',5'-cgmp protects lif against inactivation by the esterase inhibitor phenylmethylsulfonyl fluoride. | recently reported experiments suggest that human leukocyte migration inhibitory factor (lif) has properties of an esterase and a protease with substrate specificities directed against arginine esters and amides. also reported previously, the synthetic phosphodiester bis-p-nitrophenyl phosphate (bnpp) but not various phosphomonoesters preserve lif activity in the presence of the serine esterase inhibitor phenylmethylsulfonyl fluoride (pmsf). in this paper i demonstrate that guanosine 3'5'-cyclic ... | 1977 | 203999 |
| [splenic lesions during benign inoculation lymphoreticulosis]. | the authors describe the fibro-granulomatous lesions with scar formation on a splenectomy specimen removed for familial spherocytosis, eight weeks after the onset of cat scratch disease. this original observation, apparently unique in the literature, is in favour of the blood spread of the agent responsible for benign inoculation lymphoreticulosis, and suggests a pathogenic theory for the unusual visceral manifestations. | 1977 | 204030 |
| [change and new knowledge in infectious diseases of the nervous system]. | 1978 | 205519 | |
| [diffuse polymorphous inclusions in a patient treated with perhexiline maleate (author's transl)]. | case report of polyneuritis and liver dysfunction induced by perhexiline maleate in a 64 years old male patient. the ultrastructural study of nerve, liver, muscle and skin biopsies shows polymorphous, membrane bound, often multilamellar, lysosome-like inclusions, the content of which is probably complex lipids. the histochemical study of liver reveals a lipid storage, consisting mainly of triglycerides and of smaller amount of phospholipids and free fatty acids, the pattern of which is abnormal. ... | 1992 | 205835 |
| differential behavioral effects of acth 4-10 and [d-phe7] acth 4-10. | intraventricular administration of an access of acth 4-10 does not interfere with the excessive grooming behavior of rats, elicited by intraventricular administration of [d-phe7] acth 4-10. in an avoidance extinction paradigm, the two acth analogs have opposite effects. acth 4-10 counteracts the facilitation of extinction seen after [d-phe7] acth 4-10, only under conditions that treatment with acth 4-10 alone results in retardation of that extinction. the data are discussed in terms of a multipl ... | 1978 | 206319 |
| lapine rotavirus: preliminary studies on epizoology and transmission. | antibody to rotavirus was found in sera of domestic rabbits, wild cottontail rabbits and snowshoe hares. eight out of 187 stools from a rabbitry contained rotavirus, though no clinical symptoms were apparent. the virus extracted from one such stool infected a five week old seronegative rabbit and led to distention and congestion of the colon, excretion of virus in the stool and a serological response to virus. human and simian rotaviruses did not replicate in the rabbits. | 1978 | 206325 |
| thermal regulation of the fatty acid composition of lipopolysaccharides and phospholipids of proteus mirabilis. | the fatty acid composition of the lipid a moiety of the lipopolysaccharide and phospholipid fractions of proteus mirabilis changed significantly on varying the growth temperature. a decrease in the growth temperature from 43 degrees c to 15 degrees c resulted in a decrease in the palmitic acid content of the lipopolysaccharide from 19.4% of total fatty acids at 43 degrees c to 1.4% at 15 degrees c, and by the appearance of an unsaturated fatty acid residue, hexadecenoic acid. changes in the 3-hy ... | 1978 | 206438 |
| lymphocytotoxic autoantibodies eluted from in vivo propagating sarcoma cells of mice. | eluates of seyf-a cells (from polyoma virus-induced sarcoma grown in a.by mice) containing cytotoxic anti-seyf-a antibodies mediated complement-dependent cytotoxicity of normal lymph node cells. some lymphocytotoxicity was also mediated by sera of tumor-bearing mice, but the pattern of cytotoxicity was different from that exhibited by tumor eluates. the titer of lymphocytotoxic antibodies in the serum was lower than the titer of anti-seyf-a antibodies, whereas eluates exhibited similar titers to ... | 1978 | 206714 |
| medullary arteries in cerebral neoplasms. | in cerebral neoplasms, the visibility of long segments of the medullary arteries indicates white matter involvement by infiltrative or compressive disturbances. relating the mass effect to the position of the medullary arteries should allow for differentiating a primary from a secondary avascular neoplasm. when the neoplasm is vascular, the presence of neovascularity with the medullary arteries is likely to signify a high degree of anaplasia. | 2003 | 207096 |
| circular dichroism and circular polarization of luminescence of reduced nicotinamide adenine dinucleotide in solution and bound to dehydrogenases. | the cd (circular dichroism) and cpl (circular polarization of luminescence) spectra of nadph in aqueous solution were studied and found to be markedly different. the spectra were not affected by cleavage of the coenzyme molecule with phosphodiesterase. the differences are thus not due to the existence of extended and folded conformations of nadph and it is concluded that they originate in excited state conformational changes of the nicotinamide--ribose fragment. opposite signs of both the cd and ... | 1978 | 207311 |
| superoxide production by digitonin-stimulated guinea pig granulocytes. the effects of n-ethyl maleimide, divalent cations; and glycolytic and mitochondrial inhibitors on the activation of the superoxide generating system. | n-ethylmaleimide, divalent cations, ethylene glycol bis (beta aminoethyl ether) n,n,n',n',-tetraacetate, 2-deoxyglucose, cyanide, and dinitrophenol were examined for their effect on the ability of guinea pig granulocytes to generate superoxide (o(2) (-)) when stimulated by digitonin. n-ethylmaleimide (1 mm) inhibits only when added before complete activation of the o(2) (-) generating system, and at lower concentrations (0.05-0.2 mm) slows the activation process. ca(++) is required for maximum o ... | 1978 | 207722 |
| reduction mammaplasty with discovery of occult breast carcinoma in twins: case reports. | a pair of twins is presented in whom breast carcinomas were found. a reduction mammaplasty in the first twin uncovered an occult intraductal carcinoma. subcutaneous mastectomies were then done in both twins for identical, mirror-image lesions, the first twin subsequently required a radical mastectomy on the involved side. | 1991 | 208091 |
| harvesting of granulocytes for transfusion therapy by haemonetics 30. yield, morphology and in vitro functions of collected granulocytes. | by means of a haemonetics 30 blood cell separator white blood cells (wbc) were collected for transfusion purposes from 21 normal unstimulated donors. citrated hydroxyethyl starch (hes) was used as anticoagulant. a mean yield of 1.13 x 10(10) wbc was obtained in 2 1/2-3 h. half of the collected wbc were pmn cells containing a few per cent band forms, the other half lymphocytes and monocytes (12%). no shift in the distribution of wbc was found during the leucapheresis. light and electron microscop ... | 1978 | 208137 |
| adenosine receptors in smooth muscle and other tissues. | 1978 | 208381 | |
| role of cyclic nucleotides in control of smooth muscle contraction. | 1978 | 208382 | |
| equal atherosclerosis in rabbits fed cholesterol-free, low-fat diet or cholesterol-supplemented diet. | 1978 | 208585 | |
| combined effects of clofibrate and diosgenin on cholesterol metabolism in rats. | groups of male rats were fed various doses of clofibrate and diosgenin, both alone and in combination for 1 week. clofibrate suppressed the diosgenin-induced increase in hepatic cholesterol synthesis but did not alter the effectiveness of diosgenin in reducing cholesterol absorption. diosgenin did not affect the bioavailability of cpib. clofibrate reduced the diosgenin induced increase in biliary levels of cholesterol; none of the regimens altered biliary bile acids. the combination produced gre ... | 1978 | 208586 |
| ectopic acth syndrome: clinicopathological correlations. | ten out of 164 cases of bronchogenic carcinoma showed pathological evidence at necropsy of the ectopic acth syndrome. all occurred in association with oat-cell carcinoma, constituting 19% of that group. the pathological features consisted of adrenocortical hyperplasia confined to the zona fasciculata and crooke's hyaline change in the pituitary. immunoperoxidase stainable acth was detected in the pituitary but not in the carcinoma tissue, a surprising finding, which may be due to the different n ... | 1991 | 209063 |
| altered subcellular and submitochondrial localization of ctp:phosphatidate cytidylyltransferase in the morris 7777 hepatoma. | the subcellular and submitochondrial localization of ctp:phosphatidate cytidylyltransferase is altered in the morris 7777 hepatoma. mitochondria in this poorly differentiated tumor are the principal sites of cdp-diacylglycerol synthesis, in contrast to normal rat liver where the endoplasmic reticulum is most active. this enzyme activity was increased 17-fold in the outer mitochondrial membrane, and a 22% increase was noted in the inner mitochondrial membrane of the 7777 hepatoma as compared with ... | 1978 | 209110 |
| mechanisms of corticotropin action in rat adrenal cells. i. the effects of inhibitors of protein synthesis and of microfilament formation on corticosterone synthesis. | the contributions of protein synthesis and formation of microtubules and microfilaments to corticotropin-stimulated steroidogenesis in rat adrenal cell suspensions has been assessed by use of a series of inhibitors to each function. five inhibitors of protein synthesis (cycloheximide, puromycin, blastocidin s, anisomycin, and trichodermin) each exhibited time-dependent inhibition of corticotropin-stimulated steroidogenesis. for the first 30 min, steroidogenesis was more extensively inhibited tha ... | 1978 | 210838 |
| presence of hormonally-sensitive adenylate cyclase receptors in capillary-enriched fractions from rat cerebral cortex. | the 10 000 g particulate fraction from capillary-enriched fractions isolated from rat cerebral cortex was shown to possess an adenylate cyclase highly sensitive to activation by sodium fluoride, norepinephrine, epinephrine, isoproterenol and dopamine. to a lesser extent histamine and three dopamine agonists, namely m-7 (5,6-dihydroxy-2-dimethylamino tetralin), et-495 (methane sulfonate of pyribedil), and s-584 (metabolite of pyribedil) stimulated the enzyme preparation. the action of norepinephr ... | 1978 | 210869 |
| antagonistic action between cyclic amp and estrogen in phosphorylation of mammary tumor nuclear proteins. | a new protein kinase-dependent phosphorylation occurs in the nuclei of hormone-dependent, 7,12-dimethylbenz[alpha]anthracene (dmba)-induced mammary carcinoma following preincubation of tumor slices with cyclic adenosine 3',5'-monophosphate (camp). the presence of 17beta-estradiol in the medium inhibits this effect. both events have been observed in vivo in the nuclei of dmba-induced tumors. the phosphorylation pattern of nuclei in hormone-independent mammary tumor, dmba no. 1, however, is not af ... | 1978 | 210929 |
| [studies on simple methods for quantitation of "serum beta-lipoprotein" (author's transl)]. | 1988 | 211300 | |
| [determination and application of the so-called biological age]. | 1987 | 211834 | |
| the utilisation of d-galactonate and d-2-oxo-3-deoxygalactonate by escherichia coli k-12. biochemical and genetical studies. | 1978 | 211976 | |
| epr studies on model membranes of phospholipid and outer membrane proteins of proteus mirabilis. | 1978 | 212318 | |
| [action of a combination of norsulfazole and polymyxin m on the fatty acid makeup of pr. mirabilis]. | 1978 | 213013 | |
| chemotherapy studies in primary liver cancer: a prospective randomized clinical trial. | one hundred and sixty-eight patients with unresectable primary liver cancer were prospectively studied by members of the eastern cooperative oncology group. these patients were randomized to receive treatment with oral 5-fluorouracil (5fu), oral 5-fu plus streptozotocin, oral 5-fu plus methyl-ccnu or adriamycin. the single agent treatments (oral 5-fu and adriamycin) were associated with less gastrointestinal toxicity than were the oral 5-fu treatment combinations. a total of 15 partial responses ... | 1985 | 214218 |
| tubular carcinoma of the breast. | retrospective pathologic review of 636 breast carcinomas from 611 patients revealed twelve tumors which were pure low grade tubular carcinoma (tc) and nineteen tumors with features combining both low grade tubular carcinoma and invasive duct carcinoma (t&d). a control group of 23 cases consisted of invasive duct carcinoma with at least a third of the tumor surface area showing tubular formation, but without the low grade features of tubular carcinoma. life table analysis at 15 years showed a 100 ... | 1985 | 214219 |
| effect of glucagon on renin secretion in the dog. | the effects of glucagon alone or in combination with theophylline on renin section were studied in relation to renal hemodynamic responses in anesthetized dogs. the intrarenal infusion of glucagon (0.5 microgram/kg/min) increased heart rate, renal blood flow, glomerular filtration rate and urine flow without any effect on renin secretion, but at a higher dose (1.0 microgram/kg/min) it increased renin secretion significantly. theophylline (0.1 mg/kg/min) did not affect renal hemodynamics but caus ... | 1978 | 214314 |
| [biochemical basis of endogenous depression (author's transl)]. | 1978 | 214722 | |
| [eec syndrome: ectrodactyly, ectodermal dysplasia and cleft lip-palate (author's transl)]. | authors present a new and complete from of eec syndrome (ectrodactyly, ectodermal dysplasia and cleft lip-palate), analysing its' clinical, genetic and therapeutic aspects. syndrome malformations involving mainly mesenchymal tissue and with diverse clinical expression suggest a heterogenetic heredity. participation of environmental and unknown factors is not excluded. | 1983 | 215067 |
| enhancement of avian sarcoma virus-induced tumor growth after pretreatment with bcg. | pretreatment of chickens with bcg 1 week before inoculation with avian sarcoma virus had a stimulatory effect on virus-induced tumor growth in 15 of 17 cases tested. this outcome was dependent upon the injection of both bcg and the oncogenic agent into the same wing web. injection of bcg into the wing web contralateral to that used for virus inoculation or injection of a subcellular fraction of bcg into the same wing web did not affect tumor development. administration of bcg also gave rise to h ... | 1978 | 215547 |
| growth assessment in abnormal children. | growth assessments are made in children to monitor their growth with time. in children with chronic disease, these data aid in determining the effect of disease on growth and planning and evaluating therapy. stature is the most important aspect of physical growth, but weight, body composition, skeletal maturation, and sexual development are also important. methods for making these assessments are given. techniques for data reduction and statistical treatment of data comparing groups of children ... | 1984 | 215814 |
| establishment of a malignant, epstein-barr-virus (ebv)-negative cell-line from the pleura effusion of a patient with hodgkin's disease. | 1979 | 216443 | |
| polymyxin b-penicillin antagonism in proteus mirabilis. | polymyxin b protects proteus mirabilis from usually lethal penicillin concentrations. | 1978 | 217303 |
| [substances contained in matricaria chamomilla l]. | 1983 | 217547 | |
| relaxation of hormonally stimulated smooth muscular tissues by the 8-bromo derivative of cyclic gmp. | 1979 | 218117 | |
| familial lecithin:cholesterol acyltransferase deficiency. further studies on plasma lipoproteins and plasma postheparin lipase activity of a patient with normal renal function. | plasma lipoproteins and postheparin plasma were investigated in a patient with familial lcat deficiency with normal renal function and without proteinuria. as revealed by gelfiltration the large molecular weight ldl2 was not present, and myelin structures were not found in ldl1 or ldl2 when she was on her ordinary diet. after 60--65% fat diet for one week the large molecular ldl2 was found, but only in low concentration. we have no explanation for the difference in the lipoprotein abnormalities ... | 1979 | 218275 |
| hormonal control of glycogen metabolism. | in summary, we have presented evidence which relates to the action pathway of hormonal control of glycogen metabolism. in the case of insulin, there are changes demonstrable in the cyclic amp-dependent protein kinase and also in the phosphoprotein phosphatase, under conditions where no direct relationship to either cyclic amp or cyclic gmp levels are measurable. therefore, a new unknown intermediate or second messenger system is again proposed. an insulin-generated labile compound(s) which inhib ... | 1979 | 218430 |
| a modified collagenase assay method based on the use of p-dioxane. | 1979 | 218473 | |
| ultrastructural changes in rat liver cells induced by proteus mirabilis endotoxin. | changes in individual organella of rat hepatocytes developing under the effect of proteus mirabilis endotoxin (pme) were observed under electron microscope. the effect of drugs which diminish liver cell injury by pme (polymyxin, cholestyramine and hydrocortisone) on the changes was studied. | 1979 | 220929 |
| purification and properties of the membrane-bound hydrogenase from proteus mirabilis. | the cytoplasmic membrane-bound hydrogenase of the facultative anaerobe, proteus mirabilis, has been solubilized and purified to homogeneity. the purified enzyme exhibited a maximal specific activity of about 780 mumol h2 oxidized/min per mg protein (benzyl viologen reduction). the hydrogenase has a molecular weight of 205 000 and is composed of two subunits with a molecular weight of 63 000 and two of 33 000. the absorption spectrum of the enzyme was characteristic of non-heme iron proteins. the ... | 1979 | 221026 |
| modification of peptidoglycan structure by penicillin action in cell walls of proteus mirabilis. | 1979 | 221218 | |
| [physiological and pathological sleep and wakefulness behavior in the aged]. | 1978 | 222081 | |
| diagnosis of a carotid body chemodectoma with dynamic radionuclide perfusion scanning. | the first case of a carotid body chemodectoma that was diagnosed using dynamic radionuclide perfusion angiography and subsequently excised is presented. the value of this technic in the investigation of pulsatile tumors is emphasized. | 1978 | 222160 |
| an assay for plasma membrane phosphatase activity in populations of individual cells. | 1978 | 222293 | |
| lipid--lipoprotein composition in hypercholesterolemic children and their parents. | in 13 hypercholesterolemic children, re-screened for serum cholesterol after a 1-year interval, hypercholesterolemia was confirmed in only 61.5% of the cases. a tentative explanation seems to be the statistical principle of regression towards the mean. the lipid--lipoprotein analysis showed that serum and ldl cholesterol concentrations in the 13 hypercholesterolemic children and their parents were significantly higher compared to controls (children and parents). at re-screening, hyper-ldl choles ... | 1978 | 222302 |
| amplification of growth inhibition by glucocorticoid on l5178y and l1210 lymphoblasts in vivo. | one component of a factor in proteus mirabilis (factor 1) which specifically amplifies the induction of several liver enzymes by glucocorticoid in target cells also increases the growth inhibition of glucocorticoid on the ascitic form of l1210 cells and solid tumors of l5178y lymphoblasts in vivo. the growth of l5u78y and l1210 lymphoblasts was inhibited by a triamcinolone acetonide dose of over 0.5 to 1.0 mg/kg body weight. factor 1 increased the inhibitory effect of a triamcinolone acetonide d ... | 1979 | 222447 |
| investigation of the immune response to aerobic and anaerobic intestinal bacteria in a patient with crohn's disease. | the immune response to aerobic and anaerobic intestinal bacteria in a patient with crohn's disease with an intestinal fistula was investigated with various serological techniques. two aerobic bacterial species, e. dispar and p. mirabilis, and four strict anaerobic bacterial species, b. fragilis ss. fragilis, f. varium and two different strains of c. perfringens, were isolated from fistula secretion of the patient. these strains were used as antigens for tube agglutination, passive hemagglutinati ... | 1979 | 223235 |
| [clinical characteristics of patients with granulosa cell tumor, thecoma and fibroma of the ovaries]. | 1967 | 223946 | |
| transcription of endogenous c-type viruses in resting and proliferating tissues of balb/mo mice. | 1979 | 228474 | |
| adhesion of murine cells to glass microbeads: substrate-adsorbed serum proteins. | 1996 | 229116 | |
| lethal effect of complement and lysozyme on polymyxin-treated, serum-resistant gram-negative bacilli. | when genetically serum-resistant escherichia coli, klebsiella pneumoniae, and citrobacter freundii, but not pseudomonas aeruginosa or proteus mirabilis, were exposed to polymyxin b, they became susceptible to the bactericidal action of normal human and rabbit sera. in constrast, beta-lactam and aminoglycoside antibiotics did not render any serum-resistant bacteria serum-sensitive. synergy between polymyxin b and the serum bactericidal system could be demonstrated by the addition of polymyxin b t ... | 1979 | 229175 |
| interaction of cytochrome c with the phosphorprotein phosvitin. | candida krusei cytochrome c forms a molecular complex with phosphorprotein phosvitin in weakly alkaline solution of low ionic strength. at most, about 22 molecules of cytochrome c bind to a phosvitin molecule. the complex at the binding ratio below about 11 (half of the maximum ratio) as a much higher binding strength. several lines of evidence indicate that the marked difference in the binding strength is due to the difference in negative charges on phosvitin molecule concerned in the binding o ... | 1979 | 229914 |
| specificity of attachment of certain enterobacteriaceae to mammalian cells. | the specificity of adherence of various enterobacteriaceae to different mammalian cells was studied in vitro. 3h-labelled organisms of the same species isolated from various clinical sources differed significantly in their abilities to adhere to the same mammalian cells. bacteria frequently adhered better to cells derived from sites other than those analogous to their original source. bacteria did not display consistently 'high' or 'low' attachment to a variety of human and tissue-cultured cells ... | 1979 | 231084 |
| effect of serum and blood on enterobacteriaceae grown in the presence of subminimal inhibitory concentrations of ampicillin and mecillinam. | bacteria from the strains of five species of enterobacteriaceae grown in the presence of subminimal inhibitory concentrations of ampicillin or mecillinam formed into filamentous or round cells. these filamentous and round cells as well as normal control bacteria were incubated with either fresh human serum or blood, the bactericidal effects of which were then determined. in most cases, the bactericidal effect of either serum or blood on filamentous or round cells was less than the effect on cont ... | 1979 | 232297 |
| [effects of cadmium-chloride-aerosols on three generations of wistar-rats (author's transl)]. | 1979 | 232601 | |
| dna glycosylases of human lymphoblastoid cells. | lymphoblastoid cell lines were established after transformation by epstein-barr virus of peripheral lymphocytes from xeroderma pigmentosum (xp) patients and normal donors. these lines expressed b-lymphocyte characteristics. typical characteristics related to xp of these cell lines were not altered by transformation. extracts of these cells catalyzed release of uracil (ura) and 3-methyladenine (3meade) from ura-containing dna (ura-dna) and methylated dna (me-dna), respectively. these two activiti ... | 1979 | 232757 |
| [multicentric gliomas. report of a case (author's transl)]. | the criteria of culticentric gliomas, based upon histological data, were recently defined (bartzdorf et al. 1963) and permits us to distinguish them clearly from multiple gliomas. the authors report an atypical case of glioma for which the diagnosis of multicentric gliomas has been established after anatomical and histological studies. physiopathological hypotheses are discussed. emphasis is placed on the clinical pictures, diagnostic techniques as well as evolution and therapeutic aspects. | 1976 | 232963 |
| [detection of rotavirus antigen in stools by double-gel diffusion technique (author's transl)]. | 1979 | 233056 | |
| cyclic nucleotide levels in normal and biologically fractionated mouse retina: effects of light and dark adaptation. | 1978 | 233095 | |
| [circadian rhythm of poly a polymerase in rat liver nuclei]. | isolated nuclei from the liver of rats maintained under daily scheduled conditions of light (12 hrs) and food (8 hrs) showed a peak of mn2+-dependent poly (a) polymerase activity 6 hrs after the beginning of the feeding period, as shown by dna dependent rna polymerase b. in fasting animals the peak of poly (a) polymerase occurs at 18.00. | 1979 | 233201 |
| [dna-protein interactions. destabilizing activity of sheep pancreatic rnaase]. | evidence is presented that ovine pancreatic ribonuclease, a protein strictly homologous to bovine rnaase a but with one positive charge less, has a definite 'destabilizing' activity (quite similar to that of the bovine enzyme) on double-stranded dna. this action of sheep pancreas rnaase has been measured by differential spectrophotometry and determining the thermal-transition profiles of the protein-dna complexes. | 1979 | 233346 |
| in vitro activity of sisomicin, an aminoglycoside antibiotic, against clinical isolates. | sisomicin, a new aminoglycoside antibiotic which is produced by micromonospora myoensis, was studied against 565 clinical isolates of gram-negative bacilli and gram-positive cocci. with the exception of serratia marcescens, over 90% of isolates of gram-negative bacilli were inhibited by 1.56 mug/ml or less of sisomicin. sisomicin was slightly more active than gentamicin and tobramycin aganist isolates of escherichia coli, proteus mirabilis and klebsiella spp. it was substantially more active tha ... | 1975 | 234415 |
| assay of deoxyribonucleic acid homology using a single-strand-specific nuclease at 75 c. | we investigated the conditions under which a crude preparation of endonuclease s1 gives maximal hydrolysis of denatured deoxyribonucleic acid (dna) while giving minimal hydrolysis of native dna. the hydrolysis was measured by filtering and determining the acid-insoluble reaction product using 3h-labeled substrates. we also investigated various parameters in making this measurement. under appropriate conditions (in 1 mm znso-4, 0.168 m nacl at ph 4.8) denatured dna is hydrolyzed within 3% of comp ... | 1975 | 234416 |
| role of urease in pyelonephritis resulting from urinary tract infection with proteus. | the role of urease in induction of pyelonephritis was studied by treatment of proteus-infected rats with acetohydroxamic acid, a potent inhibitor of urease. infection was produced by introduction of proteus mirabilis into the bladder along with a zinc disk. controls were treated identically but received no acetohydroxamic acid. the number of bacteria per milliliter of urine was the same in both groups. the number of bacteria in the kidneys and the extent of renal damage was much greater in contr ... | 1975 | 234993 |
| glutamic acid decarboxylase, glutamine synthase and glutamic acid dehydrogenase in various areas of human brain. | 1975 | 235350 | |
| gamma-glutamyl transpeptidase of rat seminal vesicles; effect of orchidectomy and hormone administration on the transpeptidase in relation to its possible role in secretory activity. | 1975 | 235691 | |
| [response of salmonella typhi and s. paratyphi b strains from the years 1968/70 and 1974 to antibiotics]. | 1975 | 235717 | |
| aseptic endotoxemia in radiation injury and graft-vs-host diesease. | 1975 | 235772 | |
| influence of the ionic composition of the medium on the sensitivity of fertilized sea urchin ova to neuropharmacological preparations. | the removal of ca2+ from the incubation medium leads to an increase in the sensitivity of early sea urchin embryos to neuropharmacological blockers of development. the removal of so4-2-, half of the k+, as well as an increase in the ca2+ content, have no effect on the sensitivity of fertilized eggs to these preparations. the sensitivity to puromycin, colchicine, triton x-100, and 2, 4-dinitrophenol is unchanged by the removal of ca2+ from the medium. the protective action of exogenous monoamines ... | 1975 | 235791 |
| natural antibodies in healthy adults. | the serum of 100 adults living in budapest was examined for isohaemagglutinin titre with haemaglutination, for staphylococcal-antitoxin titre with haemolysis inhibition and for bacterial antibody titre against 17 different groups of bacteria with passive haemagglutination. antibody levels in males, except for certain bacterial antibodies, were somewhat lower than in females. the antibody titres, especially in men, decreased gradually from 20 to 50 years of age and were usually lower in rh negati ... | 1975 | 235827 |
| effects of morphine on the rat adrenal medulla. | 1975 | 235930 |