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enzymatic tracers in the study of vascular permeability.elucidation of the ultrastructural basis of vascular permeability was aided by the development of cytochemical techniques for visualizing the distribution, within the vessel wall, of intravenously injected peroxidatic enzymes of varying molecular size. tracer enzymes available range from 10 a (hemeoctapeptide) to 52 a (catalase) effective molecular radius. the use of enzymatic probe molecules assumes a thorough characterization of: (a) the molecular charge (isoelectric point of the native enzyme ...197990073
modulation of the host response in human schistosomiasis. i. adherent suppressor cells that inhibit lymphocyte proliferative responses to parasite antigens. 197990093
m467: a murine iga myeloma protein that binds a bacterial protein. i. recognition of common antigenic determinants on salmonella flagellins.we have studied the binding of m467, an iga murine myeloma protein, to flagellin from seven species of salmonella. it was found that m467 was reacting with antigenic determinants that were common to all the flagellins studied. these determinants were not related to serotypic antigens. electronmicrographs of unreduced m467 showed a variety of polymeric species bound to flagella in a manner that could produce immobilization as well as agglutination and precipitation through cross-linking of antige ...197990100
characterization of in vitro proliferative responses of human lymphocytes to leishmanial antigens.leishmaniasis is an intracellular protozoal infection for which host defense is believed to depend on cellular immune mechanisms. the in vitro proliferative responses of lymphocytes from patients with leishmaniasis and from control subjects to leishmanial antigens were examined. only lymphocytes from patients responded to 1 microgram of leishmanial antigen/ml, whereas both patient and control lymphocytes responded to 10 micrograms/ml. the nonspecific responses were most likely not due to a mitog ...197990105
differential growth inhibition in two human carcinoma cell lines by cyclic adenosine 5'-monophosphate analogs.the inhibition of cell replication in two human carcinoma cell lines by various cyclic amp analogs was explored. in all instances, the addition of the cyclic nucleotide phosphodiesterase inhibitor 1-methyl-3-isoburylxanthine resulted in synergistic growth inhibition by the analogs. a correlation was found between an analog's ability to inhibit growth and its ability to activate protein kinase. a differential effect of the breakdown product 8-bromo-amp (8-bramp) on cell replication in the two cel ...197990151
biosynthesis of an unglycosylated envelope glycoprotein of rous sarcoma virus in the presence of tunicamycin.cells stably infected with rous sarcoma virus were treated with tunicamycin to prevent the glycosylation of the precursor (pr92gp) to the two viral envelope glycoproteins gp85 and gp35. pretreatment of the cells for 4 h with the antibiotic resulted in a 90% reduction in [3h]mannose incorporation into total cellular glycoproteins, intracellular viral glycoproteins, and released virus particles. protein synthesis and virus particle formation were not significantly affected by the treatment. a new ...197990167
[clinical evaluation of radioassays for calcitonin, cea-s, afp and ferritin as tumor markers (author's transl)]. 200090180
[quantitative determination of copper in urine by color reaction with lead diethyldithiocarbamate]. 200090204
[determination of trophoblastic beta i globulin by means of counter immunoelectrophoresis]. 200090207
circulatory disease in association with oral contraceptive use. 200090231
timing antihypertensive medication. 200190245
hyponatraemic hypertensive syndrome with renal-artery occlusion corrected by captopril.malignant hypertension with severe hyponatraemia, hypokalaemia, depletion of sodium and potassium, and elevated blood levels of renin, angiotensin i, angiotensin ii, aldosterone, and arginine vasopressin developed in a woman with renal-artery occlusion. plasma angiotensin ii was disproportionately high in relation to exchangeable sodium. captopril, by inhibiting conversion of angiotensin i to angiotensin ii, further elevated the blood levels of renin and angiotensin i but corrected all other abn ...200190271
george stroh.the triennial confidential enquiries into maternal deaths in england and wales report 235 maternal deaths directly due to pregnancy or childbirth in 1973-75. the inquiry covers 94% of maternal deaths, and the figure is 4 times lower than the 1950s report. 37 deaths were attributed to obstetric anesthesia, some of which could have been prevented if the practising house officer had been more knowledgeable. amniotic fluid deaths numbered 15 and were largely unpreventable. while maternal mortality r ...200190322
effects of vinblastine, oncodazole, procarbazine, chlorambucil, and bleomycin in vivo on colchicine binding activity of tubulin. 200190323
[questions to television from psychopathology].progress is expected in psychopathological diagnosis by using audiovisual procedures. nowadays, a valid psychopathology concept should be broadly planned and the important method of description as well as understanding procedures should be considered. for such a model of psychopathology it seems appropriate to investigate the different psychopathological phenomenons as expression of a disturbed communication ability. concerning this outlook, new strategies are to be developed or procedures of ot ...200190381
[use of 5-bromodeoxyuridine for determining the duration of cell cycle phases].the method of differential staining of sister chromatids by means of 5-bromdesoxyuridine (bdu) was used to determine duration of the cellular cycle and its phases in a cell culture of chinese hamster. the mitotic cycle lasted for 16 hrs, g1 for 5 hrs, s for 8 hrs and g2 for 3 hrs. these values do not differ from those obtained by the autoradiography. the given method permits quicker determination of the cellular cycle phases duration as compared with the autoradiography method.200190414
[pharmacological properties and antitumor activity of a preparation diiodo-benzo-tepa in experiments].experimental data on the pharmacokinetics, toxicity, antitumor activity of the antitumor drug diiodo-benzo-tepa are reported.197990429
[complex intraoperative diagnosis of intracerebral tumors of the cerebral hemispheres]. 200190438
[cancer of the prostate]. 200190455
cells of origin of the spinocerebellar tract in the rat, studied with the method of retrograde transport of horseradish peroxidase.following injections of horseradish peroxidase into the cerebellum, the distribution of labeled neurons was studied in the whole length of the spinal cord of the rat. to find the ascending side of the axons, injections were made following hemisections at c1 or between c1 and c2. labeled spinocerebellar tract neurons were classified into two groups according to the axonal course in the spinal cord; one is composed of neurons with uncrossed ascending axons and the other, neurons with crossed ascen ...197990539
in vitro and in vivo induction of effector t cells mediating dth responses to a protein and a synthetic polypeptide antigen. 200190558
in vitro studies of the replication of moloney murine leukemia virus. 197990575
society proceedings. xx. alpine eeg meeting. courchevel, january 30--february 4, 1978 [abstracts]. 200190596
biological role of gramicidin s in spore functions. studies on gramicidin-s-negative mutants of bacillus brevis atcc9999.gramicidin-s-negative mutants of bacillus brevis atcc9999 have been isolated with a remarkly higher yield after ethidium bromide or acridine orange treatment, than after n-methyl-n'-nitro-n-nitrosoguanidine treatment. four (miv, smr170, r5 and eb 16) of 38 isolated mutants were characterized with respect to the lesion in gramicidin-s-synthesizing activity. the mutants sporulate to the same extent as the parental strain except mutant smr 170 which sporulates less. however, mutant spores were more ...197990616
cell differentiation in human gastric gland as revealed by nuclear binding of tritiated actinomycin.the nuclear binding of h3 actinomycin, which is closely linked to the differentiation phenomenon, was studied in human normal gastric mucosa. actinomycin binding decreases in cells which differentiate and becomes very low in fully differentiated cells. in the gastric pits, there is a decreasing gradient of labelling from the deeper stem cells to the well-differentiated superficial cells. this indicates that migration and renewal of the surface epithelium occurs following a 'pipe-line' system. al ...197990638
relative affinity of antisera for myelin basic protein (mbp) and degree of affinity heterogeneity. 197990641
the location and expression of idiotypic determinants in the immunoglobulin variable region--i. characterization of antibodies directed against the variable region of mouse myeloma immunoglobulins 315 and 460. 197990644
endodermal sinus tumour of the ovary -- report of a case with review of literature. 200190650
[animal experimental studies on the volume expanding effect of hydroxyethyl starch 40000 in the dog acute hemorrhagic shock].after acute hemorrhagic shock in dogs the hemodynamics of hydroxyethyl starch (mw: 40,000) are studied. the experiment shows that this plasma expander has a good efficiency for 3 to 4 hours. the indications of application of this colloidal solution are discussed.197990651
characterization of the antigenic determinants of cholera toxin subunits.the antigenic specificity of purified preparations of a subunit, b subunit, alpha chain, and gamma chain of cholera toxin was studied by double immunodiffusion and radioimmunoassay with antisera produced in rabbits and mice. rabbits immunized with a subunit produced serum antibodies which were capable of binding radiolabeled a subunit, alpha chain, and b subunit. rabbits immunized with alpha chain produced serum antibodies that would bind radiolabeled alpha chain and a subunit. rabbits immunized ...197990654
radiolabeling and isolation of thy-1 active glycolipids from murine brain and lymphoma cell lines. 200190698
lymphocyte viability and function following ex-vivo splenic perfusions in dogs. 197990722
cimetidine in bleeding peptic ulcer.the effect of cimetidine on the risk of further bleeding shortly after acute gastrointestinal haemorrhage from peptic ulcer was investigated in a double-blind randomised trial. 34 patients were given cimetidine and 32 placebo, the two groups being matched for age, sex, and severity of haemorrhage. further bleeding within a week of admission was detected clinically in 8 patients on cimetidine and 15 on placebo. cimetidine had no effect on bleeding from duodenal ulcer, but only 2 of 14 patients wi ...200190761
lymphocyte capping and carrier detection in duchenne muscular dystrophy. 200190791
post-menopausal oestrogens protect against fractures of hip and distal radius. a case-control study.to assess the efficacy of oestrogens in preventing the common major limb fractures of postmenopausal women, retrospective case-control research was used for a new purpose--to explore beneficial rather than adverse effect of treatment. postmenopausal women admitted with fractures of the hip or distal radius and matched women admitted to the orthopaedic service for other reasons were surveyed. the "risk" of the non-oestrogen users, was estimated by inverting the customary odds ratio to calculate p ...200190802
strong association between idiopathic membranous nephropathy and hla-drw3.hla a, b, and dr antigens were determined in a homogeneous group of patients with idiopathic membranous nephropathy. the frequency of hla-drw3 was significantly higher in the patients than in a control population. the frequencies of hla b8 and b18, which are in linkage disequilibrium with drw3, were also increased.200190863
enzyme immunoassays revisited. 200190867
hypothalamic releasing factor for reactive depression. 200190874
adenylate kinase in neurological diseases. 200190882
clonidine and growth-hormone secretion. 200190890
outpatient breast biopsy. 200190891
tardive dyskinesia. 200190894
acute blood-pressure reduction in malignant hypertension. 199890935
hexacarbon neuropathy. 199991030
[differential diagnosis between bile duct atresia and idiopathic neonatal hepatitis]. 199991099
the structure and evolution of the hla--bw4 and bw6 antigens.the hla--bw4 and bw6 antigenic determinants have been shown to co-migrate with hla--b determinants on gel-filtration, sucrose density gradient centrifugation and affinity chromatography, using lens culinaris lectin and antibody against human beta 2 microbulin. these and other published data imply that the hla--bw4 and bw6 determinants reside on the same polypeptide chain as other hla--b locus determinants. the implications of this in terms of the evolution of cross reacting groups of antigens at ...197991209
[distribution of dental plaque accumulation on permanent tooth surfaces in primary school children]. 199991630
malignant fibrous histocytoma producing spinal cord compression.three cases of malignant fibrous histiocytoma presented as primary paraspinal tumours causing extradural spinal cord compression. study of these cases suggests that pain relief is considerable after laminectomy but pain may recur with further tumour growth. total removal is unrealistic and diagnosis, difficult. the prognosis in terms of continuing neurological deficit after surgery followed by local radiotherapy appears poor.199991666
[method of indicating staphylococci in the bile]. 197991710
increased urine histamine after challenge of contact sensitivity in the mouse.the urinary excretion of histamine was observed daily during the development of contact sensitivity to picryl chloride in the mouse. after challenge, effected by painting the ears, urine histamine increased about four fold, while the histamine content in the ears did not change significantly. it is suggested that during challenge there is a general release of histamine, which may be the result either of an immediate hypersensitivity reaction or an effect of anaphylatoxin formation after compleme ...197992143
urinary proline to hydroxyproline ratio varies with age.urinary excretion of proline and hydroxyproline was studied in five groups of subjects, viz. controls, pituitary dwarfs, familial dwarfs, patients with fibrodysplasia ossificans progressive and patients with generalized scleroderma. the ratio pro/hyp in the urinary fraction precipitated with 5 parts of acetone (1 + 5 fraction) was close to one in children and youngsters in all the groups, while in adults it was higher than two. total pro/hyp does not give an accurate index of age.200092150
effects of painful footshock on self-stimulation behaviour of rats and influence of naloxone on this behaviour [proceedings]. 197992231
the antagonistic effect of dexamethasone and insulin on alpha-fetoprotein secretion by cultured h4-ii-e-c3 cells derived from the reuber h-35 hepatoma. 197992316
[ventricular extrasystole]. 200092397
guinea-pig alpha 1 microglobulin. isolation and properties in comparison with human alpha 1 microglobulin. 197992407
estrogen and progestin regulation of the progesterone receptor concentration in human endometrium.the concentration of the progesterone receptor (pr), both cytosol and nuclear, has been measured in the endometrium of 31 normal menstruating women during the 2 phases of their menstrual cycle and compared with the plasma 17 beta-estradiol and progesterone concentrations. there was no relationship between pr concentrations and the plasma steroid levels when the 2 phases of the cycle were considered; however, a statistically significant correlation (r = 0.70; p less than 0.005) was observed betw ...197992478
nonspecific light loss and intrinsic dna variation problems associated with feulgen dna cytophotometry.nonspecific light loss by the cell-wall-plus-cytoplasm (cwc) can cause a 50% increase in feulgen absorption units in peanut root-tip nuclei as determined by scanning at 450 nm, whereas this phenomenon is not evident with chicken erythrocytes. a two wavelength scanning method of subtracting nonspecific 450 nm absorption from 550 nm feulgen absorption values eliminated the nonspecific light loss in cwc, however, the two wavelength scanning method is time consuming and somewhat impractical with a r ...197992496
right/left differences of median nerve evoked scalp potentials in multiple sclerosis.scalp potentials evoked by electrical stimulation of the median nerve at the wrist were examined in multiple sclerosis patients and healthy controls. the latencies of the first negative peak (about 18 ms latency) of the response to right and to left-sided stimulation were compared. forty-eight of 60 measured latency differences in 15 suspected or certain ms patients were more than 3 standard deviations beyond the average difference in controls (arbitrary norm limit), whereas none of the 56 resul ...200192533
venous cannulation in children with extensive burns. 200192873
pattern of the ventilatory response to transient hypoxia in man: differences from transient hypercapnic test.the pattern of change in ventilatory variables after inhalation of pure n2 for two breaths was studied in normal children and adults. in six subjects the trends of change were compared to the ventilatory response to transient hypercapnia. we observed differences in the patterns of increasing ventilation with an initial abrupt increase of tidal volume for transient hypoxia and a progressive change for hypercapnia. in both cases respiratory frequency was progressively but unsystematically enhanced ...197992921
selective aromatic-hydrophobic binding and fractionation of immunoglobulin by means of phenyl-(ch2)n-nh-substituted agaroses. 197992988
organization of the unique and repetitive sequences in feather keratin messenger ribonucleic acid. 197992997
quantitative succinate-dehydrogenase histochemistry. iii. variations in histochemical succinatedehydrogenase activity in different cross-sections of the same muscle fibre.the variation in histochemical sdh-activity at different levels in the same muscle fibre was determined in muscle fibre cross-sections both by visual classification and quantitative determination of the formazan-deposits. this work resulted in a confirmation of the earlier micro-biochemical studies of spamer and pette (1977, 1979) and lowrey et al. (1978) that the activity of enzymes of the citric acid cycle is not homogeneously distributed in a muscle fibre over its entire length. in addition i ...200193101
an exploration of a patient-centred nursing approach in the admission of selected surgical patients: a replicated study.it is well recognized that admission to hospital is a stressful experience for patients, and little attention is directed towards helping patients to adapt to hospitalization. this paper reports the replication of a descriptive study which explored the patient's welfare after the use of a patient-centred nursing approach designed to alleviate stress on admission to hospital. it also attempts to determine the patient's perception of the nurse during the implementation of the admission procedure, ...200193119
immunogenetic and immunochemical studies of h-2 antigens of foreign haplotypes on tumour cells. 200193131
conjunctival transplantation as an alternative to keratoplasty.rehabilitation of the ocular surface is frequently desired following severe chemical and thermal injury. while keratoplasty, both lamellar and penetrating, has been the usual mode of therapy, chronic healing deficits and graft rejections as a result of heavy vascularization often lead to an unsatisfactory result. in unilateral injury, conjunctival transplantation from the opposite, uninvolved eye offers an alternative therapy which avoids both intraocular surgery and the introduction of immunolo ...200193258
complications associated with therapeutic soft contact lenses.the complications of therapeutic hydrophilic contact lens wear are systematically outlined. hypoxia is the major cause of initial patient failure as well as the long-term problems of corneal edema, neovascularization, and susceptibility to infection. the common difficulties with lens breakage, lens deposits, poor lens retention, and other entities are discussed. suggestions for avoiding and treating various complications are given, including updated indications and contraindications for fitting ...200193261
[palliative therapy of stenosing reflux esophagitis]. 200193354
severe skin pain after puva treatment.severe skin pain lasting one or two months occurred in 8 of 210 patients treated with puva. the pain started 4--8 weeks after the initial dose, mostly about one week after discontinuation of the treatment. it was a prickling, burning pain, usually coming in bouts and confined to limited areas "deep under the skin". in some respects the pain was related to itching, but the patients could easily distinguish between the two sensations. a variety of drugs was tried, but none had any noteworthy effec ...200193376
refsum's disease. eye manifestations in a patient treated with low phytol low phytanic acid diet.the cardinal eye symptoms of refsum's disease are night blindness, retinal pigmentary degeneration and constriction of the visual fields. similarities with or differences from retinitis pigmentosa are discussed. a 39-year-old male has had manifestations of refsum's disease from the age of 7 years and has been on a low phytol low phytanic acid diet for the last 13 years. peripheral ring scotomas were present. some reduction of the visual fields has been recorded, but only in the far periphery. th ...199993392
dipyridamole affects myocardial adenosine kinase activity.adenosine kinase (en 2.7.1.20) from rat and dog heart was purified until it was devoid of adenosine deaminase activity. a stimulation of adenosine kinase activity by dipyridamole was observed when the enzyme was assayed under optimal conditions. at low substrate concentrations adenosine kinase was inhibited by the drug. it increased the km for adenosine sevenfold. the effects of dipyridamole were mg2+-dependent. the adenosine-sparing action of dipyridamole at low substrate concentrations is in k ...197993442
[cerebrospinal fluid monoamine metabolites and cyclic nucleotides in the patients with epilepsy (author's transl)]. 199993481
symposium on uropathology. 197993566
genetic variation in the m antigen of group a streptococci: reassortment of type-specific markers and possible antigenic drift.the phylogenetic relationships of 73 strains of group a streptococcus isolated over a six-year period from a population with a high prevalence of streptococcal infections were analyzed with use of four serotype-specific markers: the serum opacity factor (of), the t antigen, the determinant of the m antigen that precipitates with antibody, and the m antiphagocytic determinant. of inhibition tests divided the strains into five subtypes: a, b, c, d, and e. strains within subtypes a, b, and c shared ...197993611
treatment of myasthenia gravis. report on 139 patients.in the treatment of myasthenia gravis (mg) considerable progress has recently been achieved. our experience is based on the observation of 139 patients with an average follow-up of 3 years and 4 months. a treatment plan and results are presented. indications for thymectomy: all cases of mg in adult life, apart from ocular myasthenia without radiological thymoma and without electrophysiological and pharmacological signs of generalization; before puberty only cases with radiological thymoma and se ...199993623
the prognosis of intraventricular hemorrhage.a series of 40 patients with blood in the cerebral ventricular system demonstrated by computed tomography (ct) is presented. overall prognosis was found to be better than expected from the literature. nearly half of the patients are still alive; 12 of the 40 patients in this study had no significant residual disability. the results suggest that the rupture into the ventricular system by itself is of minor importance. however the clinical condition of the patient on admission, site and origin of ...199993626
differentiation of normal pressure hydrocephalus and cerebral atrophy by computed tomography and spinal infusion test.the diagnostic value of computed tomography (ct) and spinal infusion test (sit) was investigated in 27 patients with normal pressure hydrocephalus (nph) and 35 patients with cerebral atrophy. the most consistent ct finding of nph was dilatation of the temporal horns, that of cerebral atrophy widening of the convexity sulci. however, 43% of patients with cerebral atrophy demonstrated no cortical atrophy. the sit showed an excellent relation with isotope cisternography and continuous intracranial ...199993629
[studies on elastase in pancreatic diseases (author's transl)]. 199993654
1-isoamyl-3-isobutylxanthine: a remarkably potent agent for the potentiation of norepinephrine, histamine, and adenosine-elicited accumulations of cyclic amp in brain slices. 197993674
location of bladder preganglionic neurons within the sacral parasympathetic nucleus of the cat.sacral parasympathetic preganglionic neurons innervating the urinary bladder were labelled by applying horseradish peroxidase (hrp) to branches of the pelvic nerve at the neck of the bladder. bladder preganglionic cells were located primarily in the intermediolateral grey matter of sacral cord segments 1, 2 and 3 and extended from the ventral end of the central canal to the inferior margin of the dorsal horn. dendrites extended into the dorsolateral funiculus, toward the lateral edge of the dors ...197993725
[enzyme therapy in pathogenic treatment of extrapulmonary tuberculosis (experimental study)]. 197993744
the weight of the dorsal, lateral and medial prostatic lobes in man.the weight of the prostatic lobes in man was determined in an atuopsy series comprising 158 cases. in children the medial pair of lobes formed half of the prostate gland. the "normal" mean weights in adult men of the dorsal, lateral and medial pair of lobes were 3.6, 3.4 and 4.3 g, respectively. in adult men there was no change in lobe weight with increasing age. in subjects who died after protracted disease all of the prostatic lobes had decreased in weight. in subjects with periurethral adenom ...197993779
intra-operative frozen section technique for pituitary adenomas.orange g-hematoxylin stains performed on frozen sections from the sella turcica had a diagnostic accuracy of over 90% when compared to permanent sections on the same tissue. this technique allows the pathologist to make an intra-operative contribution to the establishment of tumor margins in the selective removal of pituitary adenomas.199993851
myelin basic protein treatment of experimental allergic encephalomyelitis in monkeys.treatment of experimental allergic encephalomyelitis (eae) in two strains of monkeys with large amounts of myelin basic basic protein (bp) fails unless an adjunct is also used. in both strains the adjunct by itself is more effective than bp by itself, but in the one strain which could be investigated sufficiently, the combination can be made almost totally effective in reversing eae. the adjunct varies with the strain of monkey, an antibiotic in macaca mulatta and a steroid in macaca fasciculari ...197993874
thirst and renal excretion of water and electrolytes during pyrogen fever in dogs.body temperature, water intake, urine output, sodium and potassium excretion, osmolal and free water clearance, plasma osmolality, sodium and potassium concentrations and osmotic thirst were examined in conscious dogs during pyrogen fever and compared to those found under control conditions. arterial blood pressure and central venous pressure were also measured in some experiments. administration of pyrogen produced transient but significant decreases in urine output and striking increases in th ...197993885
semicarbazide-sensitive amine oxidase in rat aorta: a plasma-membrane enzyme [proceedings]. 197993954
effects of tamoxifen on the binding and metabolism of testosterone by human prostatic tissue and plasma in vitro.the in-vitro metabolism of testosterone in benign and malignant prostatic tissue was examined and distinct quantitative differences between the two types of specimens were observed. the major metabolite of testosterone in the hyperplastic prostate was 5 alpha-dihydrotestosterone and a high 3 alpha(beta)-hydroxysteroid dehydrogenase activity was also detected. in the malignant tissue, 5 alpha-reductase activity was considerably reduced and there was little or no androstanediol formed; the 17 beta ...197994084
[cases of leukemoid plasma cell reaction]. 199994128
[uniformity and standardization of methods is the way to increased quality in clinical laboratory studies]. 199994135
[perception of patients in intensive care units. problems perceived and expectations in relation to nursing care]. 199994171
photolysis of mast cells in presence of protoporphyrin.the effects of ultraviolet and visible irradiation in presence of protoporhyrin upon mast cells were investigated. rat peritoneal mast cells were suspended in a medium containing varying concentrations of protoporphyrin and were irradiated using a mercury vapor lamp. the release of histamine is related to both the concentrations of protoporphyrin and the period of irradiation. comparatively negligible amounts of histamine were released when the cells were irradiated in absence of protophyrin or ...197994207
erythemal and pigmentary phototest reactions in polymorphic light eruptions.the erythemal and pigmentary skin reactions in 110 patients with chronic polymorphic light eruptions (pmle) and in 154 control persons were investigated by phototesting with a medium pressure mercury lamp. recording the erythemal threshold (med) at 2-h intervals for up to 24 h after irradition disclosed no differences between pmle patients and controls. there was, however, a tendency for the erythemal reaction to subside more slowly in the pmle patients; this tendency reached a statistically ver ...199994208
[histochemical studies on the structure and the age changes of descemet's membrane in cattle (author's transl)].descemet's membrane of 15 cattle-corneas, aged 6 month to 13 years was studied by various histochemical and morphometric methods. 3 zones could be differentiated. zone 1 is relatively small and does not show significant changes with age; zone 2 comprises the main part of descemet's membrane, its diameter increased with age. zone 2 is rich in sulfated glycosaminoglycans. zone 3, below the endothelial lining, does not develop before the 3rd and 5th year of life and stains different from zone 2.197994246
the identification of human h-y antigen and testicular transformation induced by its interaction with the receptor site of bovine fetal ovarian cells.beta 2m(-), hla (-) daudi human male burkitt lymphoma cells excreted a group of protein subunits that shared three distinctive characteristics; their conspicuously longer half-lives compared to more hydrophilic daudi excreted proteins, their tendency to form progressively larger polymers by means of interchain disulfide bridges, and the extreme hydrophobicity of these polymers. the plasma membrane of extragonadal somatic cells absorbed 1.2 to 2.8% of these hydrophobic proteins. the unoccupied h- ...197994287
a model study for determining the mechanism of exposure of leukemia-specific antigen on dinitrophenylated leukocytes. 197994299
priming increases the amount of interferon mrna in poly(ri).poly(rc)-treated l cells.priming by mouse interferon pre-treatment resulted in an accumulation of interferon mrna in poly(ri).poly(rc)-treated l cells, starting early in the period of interferon synthesis. on electrophoresis, the priming activity of an interferon preparation co-migrated with the antiviral activity, which suggests identity of the functional principle(s) for these activities.197994345
comparison of the antibodies elicited by the individual structural polypeptides of foot-and mouth disease and polio viruses.antibody produced against preparations of vp1, one of the four structural polypeptides of foot-and-mouth disease virus, neutralized the virus and reacted with both full and empty particles in radioimmunoassays (ria). antiserum against vp2 reacted with artificial empty particles of the virus but not with full particles. in contrast, none of the individual polypeptides of poliovirus produced antisera which neutralized the virus nor reacted with it in ria. however, antisera produced with vp1 and vp ...197994352
thyroid hormone regulation of alpha-adrenergic receptors: studies in rat myocardium.the effects of alterations in thyroid state on cardiac alpha-adrenergic receptors were investigated by the binding of [3h]dihydroergocryptine (dhe), a potent alpha-adrenergic antagonist. in seven experiments, cardiac membranes from euthyroid rats bound 47 +/- 9 fmoles dhe/mg protein (mean +/- se) at saturation and demonstrated a dissociation constant (kd) of 2.5 +/- 0.4 nm. hyperthyroidism, produced by parenteral injection of triiodothyronine, significantly reduced the binding of dhe at all conc ...197994388
[adjuvant and palliative treatments for colo-rectal cancer]. 200094441
[therapeutic effectiveness and tolerability of p-isobutylphenylpropionate of lysine, in parenteral administration, in subjects with hyperalgic forms of rheumatic arthropathy]. 200094559
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