| extracellular haemolysin of proteus penneri coded by chromosomal hly genes is similar to the alpha-haemolysin of escherichia coli. | extracellular haemolysin of four proteus penneri strains was characterized as a polypeptide of approximately 110 kd. the chromosomal dnas of these strains cleaved with hind iii showed three fragments hybridizing with a dna probe containing cloned haemolysin (hly) genes of escherichia coli. the results presented here suggested that the haemolysin of p. penneri strains is chromosomally determined and similar to the alpha-haemolysin of e. coli. | 1990 | 2205224 |
| [proteus syndrome]. | two new cases of proteus syndrome are reported. this congenital syndrome, first described in 1983, comprises gigantism of extremities, body hemihypertrophy, pigmented nevi and multiple tumors (subcutaneous, lipomas, hamartomas). this syndrome belongs to the same group as recklinghausen disease, maffucci or klippel-trenaunay syndromes. the prognosis is not well known but mostly depends on functional and psychologic consequences of important deformations. | 1990 | 2206106 |
| disappearing staghorns. | | 1990 | 2207556 |
| the proteus syndrome: association with nephrogenic diabetes insipidus. | in this report we present the first case of proteus syndrome associated with nephrogenic diabetes insipidus. the case is a 9-month-old girl, with macrodactyly of both feet and left hand, syndactyly of the 3rd and 4th fingers of the left hand, soft tissue masses in the paravertebral and gluteal regions, and a hyperpigmented epidermal nevus with hyperkeratosis on the left half of the body. | 1990 | 2208765 |
| in vitro activity of temafloxacin hydrochloride (ta-167 or a-62254), a new fluorinated 4-quinolone. | the in vitro antibacterial activity of temafloxacin hydrochloride (ta-167 or a-62254) was evaluated against a wide variety of clinical isolates and compared with those of other fluoroquinolones. the potency (mic90) of the compound against gram-positive aerobic bacteria was higher or comparable to those of ciprofloxacin, ofloxacin, and norfloxacin. against most gram-negative enteric bacteria and pseudomonas species, temafloxacin was less active than ciprofloxacin, but was generally as active as o ... | 1990 | 2209168 |
| lytic effect of vibrio cholerae elastase on gram-positive and -negative bacteria. | elastase of vibrio cholerae caused the lysis of freshly grown cells of gram-negative (pseudomonas aeruginosa, proteus vulgaris, salmonella paratyphi a and klebsiella pneumoniae) bacteria. gram-positive (staphylococcus aureus and s. epidermidis) organisms were resistant to this enzyme. heat killed and lyophilized gram-positive and -negative bacteria (except s. aureus and s. epidermidis) showed higher sensitivity to elastase. both gram-negative and -positive bacteria were lyzed maximally by elasta ... | 1990 | 2210489 |
| antibacterial activity of cefpodoxime proxetil in a pharmacokinetic in-vitro model. | the antibacterial activity of cefpodoxime proxetil was studied in an in-vitro model simulating doses of 100, 200 and 400 mg. strains of klebsiella spp. proteus mirabilis, escherichia coli, streptococcus pyogenes, and haemophilus influenzae were effectively reduced by a dose of 200 mg. while for esch. coli no dose-activity relationship was observed--the maximal effect was achieved with a simulated dose of 100 mg--staphylococcus aureus could be reduced effectively only by a simulated dose of 400 m ... | 1990 | 2211449 |
| antibacterial effect of meropenem and imipenem on proteus mirabilis. | phase-contrast microscopy, killing-curves and turbidimetric growth-curves were used in a comparative study of the antibacterial effects of a new carbapenem, meropenem (sm 7338) and imipenem on five strains of proteus mirabilis. despite the low mic (0.2 mg/l) of imipenem for the five strains included in our study, the mbc remained relatively high (4.4 mg/l). during the first few hours of incubation, imipenem induced large lemon-shaped cells while the turbidity increased without substantial change ... | 1990 | 2211455 |
| [proteus adhesion to intestinal epithelium]. | the adhesive properties of proteus strains isolated from different sources have been studied under conditions similar to the real interaction of microorganisms with the epithelial cells of intestine. a comparison of the adhesive properties of proteus and of colon bacillus has shown that the value of the strong adhesion to the mucosa of proteus isolated under enterocolitis at the same bulk concentrations of the infectious suspension is 2-3 order less than that of e. coli. the adhesion of proteus ... | 1990 | 2215291 |
| the diagnosis of bacteriuria during pregnancy. | three diagnostic tests, nitur, urobact, and uricult, were evaluated in the detection of bacteriuria in 865 pregnant women. as reference method agar culture was performed. heavy growth (greater than 10(5) cfu/ml) of urinary tract bacteria was considered a true positive result and demonstrated in 58 (6.7%) of the women, 14 of whom had gram-negative rods. the sensitivity of the nitrite test was extremely low (0.13). the test gave negative results in eight of 17 specimens yielding heavy growth of es ... | 1990 | 2218158 |
| hemolysin as a marker for serratia. | all serratia marcescens strains (total of 33) of different sources were hemolytic including clinical strains previously classified as being nonhemolytic. dna fragments of the two hemolysin genes hybridized with the chromosomal dna of s. marcescens, s. liquefaciens, s. kiliensis, s. grimesii, s. proteamaculans, s. plymutica, s. rubridaea which were also hemolytic. the restriction pattern of the hemolysin locus differed in each strain. s. ficaria and s. marinorubra expressed a different hemolysin ... | 1990 | 2222120 |
| [adrenal abscess in the newborn: a case report and review of the literature]. | this is a case report concerning a 22 day newborn referred to us having an abdominal tumor, fever, an irritable nature and feeding refusal, born dystocically due to the retention of the shoulders and having an apgar score of 5/8. when admitted the presence of the tumor was corroborated in the right flank occupying the right renal fossa and measuring 5 x 8 cm, non-mobile and painless. studies revealed a diagnosis of calcified right adrenal hemorrhage versus neuroblastoma. during surgery a right a ... | 1990 | 2222825 |
| [toxic pulmonary and neuronal reactions to nitrofurantoin]. | | 1990 | 2223723 |
| in vitro activity and beta-lactamase stability of the new oral cephalosporin bay v 3522. | the activity of the new oral cephalosporin bay v 3522 was compared to that of six other beta-lactam agents. bay v 3522 inhibited methicillin-susceptible staphylococcus aureus and staphylococcus epidermidis at less than or equal to 2 micrograms/ml, compared to mics of greater than or equal to 8 micrograms/ml for the other cephalosporins tested. it was more active against streptococcus pyogenes (mic less than or equal to 0.06 microgram/ml) than cefuroxime, cefixime, cephalexin and cefaclor. groups ... | 1990 | 2226499 |
| pelvic lipomatosis in the proteus syndrome: a further diagnostic sign. | | 1990 | 2226574 |
| molecular analysis of the bacteroides fragilis reca gene. | the nucleotide sequence of a 2.5-kb dna segment containing the bacteroides fragilis reca gene was determined. the coding region of the reca gene specifies a protein of 318 amino acids. the reca protein of b. fragilis shows significant homology with that of escherichia coli, thiobacillus ferrooxidans, pseudomonas aeruginosa and proteus mirabilis. no sos box characteristic of lexa-regulated promoters could be identified in the 5'-noncoding region of the b. fragilis reca gene. promoter activity of ... | 1990 | 2227455 |
| a three year survey of clinical isolates in the united kingdom and their antimicrobial susceptibility. | a united kingdom national survey of clinical isolates and their antimicrobial susceptibility was performed, with 61 participating hospital laboratories, between 1986 and 1989. each centre used microbe base, a commercial suite of micro-computer programs which can record and analyse antimicrobial susceptibility data informative on 366,853 bacterial isolates and their antimicrobial susceptibility was received from hospital and domiciliary specimens; candida spp. accounted for a further 9121 isolate ... | 1990 | 2228831 |
| [synergy between sulbactam and ampicillin or cefoperazone in antimicrobial activity against beta-lactamase producing microorganisms. results with the use of microdilution broth method]. | antimicrobial activities of sulbactam (sbt) with ampicillin (abpc) or with cefoperazone (cpz), in other words, the effects of sbt, an beta-lactamase inhibitor, against beta-lactamase producing strains of clinical isolates, were studied using microdilution broth method. 1. beta-lactamase producing strains such as staphylococcus aureus, branhamella catarrhalis, haemophilus influenzae, escherichia coli and klebsiella pneumoniae decompose benzylpenicillin (pcg) which is one of substrates of the acid ... | 1990 | 2232151 |
| antimicrobial activity of naphthoquinones from fusaria. | twenty-two naphthoquinone compounds isolated or derived synthetically from culture extracts of fusarium solani and f. oxysporum were examined for antimicrobial activity. fifteen exhibited antibiotic activity against staphylococcus aureus, and 12 were active against streptococcus pyogenes, but none were active at the highest rate of 128 micrograms/ml against escherichia coli, klebsiella pneumoniae, salmonella typhi, proteus vulgaris, serratia marcescens, or pseudomonas aeruginosa. of 8 plant path ... | 1990 | 2233983 |
| [the enterotoxigenic capacity of hemolysin-producing strains of proteus isolated in acute intestinal infections in children]. | the capacity of p. mirabilis and p. vulgaris strains isolated in acute enteric infections in children for producing enterohemolysin, a new type of hemolysin, has been shown. the relationship between the capacity of proteus cultures for producing enterohemolysin and their capacity for inducing toxic secretory reaction on a ligated loop on the small intestine of rabbits in the absence of known thermostable and thermolabile antitoxin in bacteria. | 1990 | 2239005 |
| colobronchial fistula: a rare complication of crohn's colitis. | a 29-yr-old white woman presented with chronic pneumonia in the left lower lobe and with left pleural effusion. she was known to have inflammatory bowel disease, but she was asymptomatic under maintenance treatment with 5-asa. she received numerous antibiotic regimens according to susceptibility testing of microorganisms cultured from sputum and bronchial lavage and on an empiric basis was also given antituberculosis treatment, but there was no clinical improvement or change in the chest radiogr ... | 1990 | 2240849 |
| [selective medium for corynebacterium kutscheri and localization of the organism in mice and rats]. | a new selective medium for isolation of corynebacterium kutscheri (ck) from animals suffering subclinical infection was made by adding furazolidone, nalidixic acid and corimycin to the heart infusion agar base, this being named fnc agar. the fnc agar inhibited the growth of gram-negative rods, pseudomonas aeruginosa, proteus sp. and gram-positive cocci but did not affect the growth of ck. when this medium was used to isolate ck from the oral cavity and cecal contents of mice and rats, two of 6 c ... | 1990 | 2242765 |
| complete nucleotide sequence of the pvuii restriction enzyme gene from proteus vulgaris. | | 1990 | 2243794 |
| the fumarate reductase operon of wolinella succinogenes. sequence and expression of the frda and frdb genes. | the genes of the fumarate reductase of wolinella succinogenes are organized in an operon. the three structural genes in the order frdc, frda, frdb, are preceded by a common promoter (körtner et al. 1990) and followed by a terminator of transcription. the proteins encoded by the genes are identical with the subunits present in the isolated enzyme. frda and frdb are hydrophilic proteins consisting of 656 and 238 amino acids, respectively. the 12 cysteine residues present in frdb form 3 ferredoxin- ... | 1990 | 2244791 |
| numerical analysis of electrophoretic protein patterns of morganella morganii strains from faeces, wound, urine and other clinical sources. | sixty-five strains of morganella morganii (mainly of human origin) were characterized by one-dimensional sds-page of cellular proteins. the strains came from various countries; 13 were from stools (including one from a toucan), 13 from wounds, 11 from urine, five from blood (including one from a snake), five from the respiratory tract (four sputum, one lung), 12 from miscellaneous sources and six from unknown sources. the protein patterns, which contained 45 to 50 discrete bands, were highly rep ... | 1990 | 2246146 |
| the use of intestinal antibiotics to delay or prevent infections in patients with burns. | bacterial colonization and infection of wounds in seriously burned patients often comes from the patient's indigenous bowel flora. a prospective randomized clinical trial that involved 30 patients with 20% or greater total body surface area burns was undertaken to evaluate the use of a standard antibiotic bowel preparation in the delay or prevention of bacterial colonization of the burn wound and sepsis. certain enteric bacteria were seen less frequently in the treated group (enterobacter organi ... | 1990 | 2246313 |
| absence of significant bacteremia during urinary catheter manipulation in patients with chronic indwelling catheters. | the objective of this study was to quantify the microorganisms present in blood at urinary catheter removal and at reinsertion in patients with chronic indwelling urinary catheters. this was a prospective study during a 4-month period at a university-affiliated geriatric medical center. our subjects were 33 patients with chronic indwelling urinary catheters and positive urinary cultures; the urinary catheter was usually changed once a month. a peripheral vein line was used for blood withdrawal a ... | 1990 | 2246457 |
| cefpodoxime: comparable evaluation with other orally available cephalosporins. with a note on the role of beta-lactamases. | the antibacterial activity of cefpodoxime, a new orally active methoxy-imino cephalosporin was evaluated in 470 recent isolates of gram-positive cocci and gram-negative rods from clinical specimens and compared to that of other orally active beta-lactam compounds. cefpodoxime was highly active against ampicillin-resistant enterobacteria producing the plasmid-mediated tem-1, tem-2 or oxa-1 enzymes, as was the case for the other newer compounds. however, it was poorly active against cefuroxime-res ... | 1990 | 2248685 |
| bacteria and arthritis. | | 1990 | 2249058 |
| interactions of escherichia coli and proteus mirabilis with mouse mononuclear phagocytes. | five strains of enterobacteria (three of escherichia coli and two of proteus mirabilis) were studied to assess and compare their phagocytic uptake and intracellular killing by mouse macrophages. each strain was injected intraperitoneally into separate groups of mice and peritoneal exudate cells were harvested after 3 min for phagocytosis to occur in vivo. acridine orange staining showed that there were approximately 10-fold fewer intracellular p. mirabilis than e. coli cells. the average numbers ... | 1990 | 2250285 |
| functional similarity between the haemolysins of escherichia coli and morganella morganii. | haemolysin produced by a clinical isolate of morganella morganii was examined for antigenic relatedness to the haemolysin of escherichia coli and for similarities in mode of action. the m. morganii haemolysin migrated in sds-page as a single protein band with a slightly higher molecular weight than that of e. coli haemolysin. several murine monoclonal antibodies against e. coli haemolysin cross-reacted with the m. morganii haemolysin in western blots. diminished haemolysis in the presence of osm ... | 1990 | 2250286 |
| [proteus peritonitis-bacteremia in mice--a model for studying postvaccinal proteus immunity]. | the dynamics of the formation of postvaccinal immunity after immunization with preparations obtained with the use of hydroxylamine (ha) preparations from proteus strains of different o serogroups, salmonella minnesota re-mutant and the common antimicrobial antigen isolated from escherichia coli 14 has been studied on mice with proteus peritonitis-bacteremia used as a model. the study has revealed that intraperitoneal immunization with proteus ha preparations stimulates the phagocytic activity of ... | 1990 | 2251896 |
| homology among bacterial catalase genes. | catalase activities in crude extracts of exponential and stationary phase cultures of various bacteria were visualized following gel electrophoresis for comparison with the enzymes from escherichia coli. citrobacter freundii, edwardsiella tarda, enterobacter aerogenes, klebsiella pneumoniae, and salmonella typhimurium exhibited patterns of catalase activity similar to e. coli, including bifunctional hpi-like bands and a monofunctional hpii-like band. proteus mirabilis, erwinia carotovora, and se ... | 1990 | 2253114 |
| proteus mirabilis isolation as a sign of nasal foreign body. | | 1990 | 2253439 |
| influence of temperature on beta-lactamase production and outer membrane proteins in gram-negative rods. | the influence of temperature (ranging from 28 to 42 degrees c) was studied on the phenotypic expression of chromosomally mediated beta-lactamases in gram-negative clinical isolates and in their beta-lactamase-depressed resistant counterparts. the enzymes were expressed most intensely at lower temperatures (28 or 32 degrees c). in most strains the enzyme was barely detectable at growth temperatures of 42 degrees c independent of the inducer employed. the release of the enzyme into the surrounding ... | 1990 | 2253497 |
| circulation in italy of beta-lactamase-producing strains within the major groups of bacterial pathogens. | a multicenter study was undertaken in italy to assess the circulation of beta-lactamase-producing organisms and their current incidence within the major groups of bacterial pathogens. almost four thousand strains, all freshly isolated from clinical material, were examined at four centers serving different areas of italy. despite some significant center-to-center differences, this survey documented the occurrence of a large overall circulation of beta-lactamase-producing organisms among clinical ... | 1990 | 2253734 |
| functional activity of individual abscess neutrophils from mice. | in the absence of antibiotic therapy, viable bacteria can persist within intra-abdominal abscesses in mice for at least 10 weeks. the mechanisms contributing to this survival are unknown, but abscess-derived neutrophils have impaired abilities to kill, in vitro, organisms engulfed in vivo. in order to determine whether subpopulations of abscess neutrophils might be discernible on the basis of phenotypic or functional criteria, cells from murine intra-abdominal abscesses were examined for phagocy ... | 1990 | 2254025 |
| nickel availability and urease expression in proteus mirabilis. | cells of proteus mirabilis, previously grown in nutrient broth (nb), exhibited an increase in urease activity during subsequent incubation in mineral medium even when protein biosynthesis was inhibited. during growth in nb, degradation of amino acids obviously led to the formation of nickel-complexing metabolites, and nickel ions were therefore unavailable for maximal expression of enzymatically active urease; this inhibition of urease biosynthesis was overcome by the addition of nickel to the g ... | 1990 | 2256779 |
| pefloxacin in the treatment of septicaemia: three years' experience. | sixty cases of septicaemia treated with pefloxacin, alone (30) or in combination with other antibiotics (30) were analysed retrospectively. a satisfactory outcome was achieved in 33 (87%) of 38 evaluable gram-negative septicaemias (including success in 25 of 29 treated with pefloxacin alone) and in 15 of 21 staphylococcal septicaemias, mainly treated with combinations of antibiotics. failures and relapses were associated with a variety of local or systemic underlying conditions. | 1990 | 2258358 |
| antibody coated bacteria in urine of patients with recent spinal injury. | twenty patients with an acute spinal injury were prospectively studied to assess the clinical importance of antibody coated bacteria (acb) in the urine and the association among the different bacterial species with a positive antibody coated bacteria test. clinical urinary tract infection was associated with a positive acb test on 45% of occasions. three hundred and ninety nine urine samples containing 541 bacterial isolates were assessed for the presence of acb; 13% were found to be positive an ... | 1990 | 2262569 |
| [susceptibilities of uropathogenic bacteria to ampicillin, cefazolin, cefmetazole and gentamicin. nine-year survey of changing patterns of susceptibilities]. | we analyzed antibiotic susceptibilities of urinary isolates of escherichia coli, klebsiella spp., proteus mirabilis, and indole (+) proteus group to ampicillin (abpc), cefazolin (cez), cefmetazole (cmz) and gentamicin (gm) in 69 laboratories in 1988 and also studied changing patterns of susceptibilities from 1980 to 1988. minimal inhibitory concentrations were determined using the agar dilution method (mueller-hinton agar, bbl) with inoculation of 10(6) cfu/ml of bacteria. ninety to 99% of the s ... | 1990 | 2262960 |
| [clinical laboratory approach to estimate effective administrative dose of minocyclin. reevaluation of in vitro mic break points in disc susceptibility test]. | antimicrobial activities of minocycline (mino) against various clinical isolates, 270 strains obtained in 1988, were determined and the reliability of the mino disc susceptibility test in estimating approximate values of mics was studied. clinical significance of a 4 category system for the interpretation of the disc tests, which is widely used in japan, and that of a 3 category system used in the usa and europe, were also evaluated to determine which system would be more suitable for the evalua ... | 1990 | 2262962 |
| nonspecific resistance-enhancing activity of zymosan in experimental bacterial infections. | the nonspecific resistance-enhancing activity of zymosan on experimental bacterial (escherichia coli, klebsiella pneumoniae, proteus mirabilis, pseudomonas aeruginosa, serratia marcescens and staphylococcus aureus) infections was investigated. zymosan, being of very low toxicity, significantly enhanced nonspecific resistance to the above bacteria. the enhancement was the most pronounced 2 to 5 days after zymosan treatment. | 1990 | 2270737 |
| bacteria and arthritis. | | 1990 | 2271839 |
| fimbrial hemagglutinins in klebsiella pneumoniae. | eleven klebsiella pneumoniae strains were isolated from urine specimens which were examined for their ability to produce hemagglutinins (has). bacteria were grown under various culture conditions. suspension of bacteria grown in broth or on phosphate-buffered nutrient agar (pba) were tested for agglutination in the presence and absence of 2% (w/v) d-mannose, on rockedtiles at 4 degrees c and ambient temperature with mangroup-o(m), fowl(f), ox(o), guinea-pig(g), horse (h), rabbit (r) and sheep (s ... | 1990 | 2273249 |
| dna sequence analysis of the reca genes from proteus vulgaris, erwinia carotovora, shigella flexneri and escherichia coli b/r. | the complete nucleotide sequences of the reca genes from escherichia coli b/r, shigella flexneri, erwinia carotovora and proteus vulgaris were determined. the dna sequence of the coding region of the e. coli b/r gene contained a single nucleotide change compared with the e. coli k12 gene sequence whereas the s. flexneri gene differed at 7 residues. in both cases, the predicted proteins were identical in primary structure to the e. coli k12 reca protein. the dna sequences of the reca genes from e ... | 1990 | 2274037 |
| [spectrum of pathogens in hospital infections in onco-urologic patients and their sensitivity to antibacterial drugs]. | retrospective examination of case records and laboratory findings related to 155 patients discharged from the urological department of the all-union oncology research centre, academy of medical sciences of the ussr within a period of 3 months showed that 41.9 per cent of the oncourological patients had infectious processes requiring antibacterial therapy. among 80 infectious episodes 62 or 77.5 per cent were of intrahospital origin. there was a relationship of the frequency of the infections to ... | 1990 | 2275593 |
| skin tissue fluid levels of cefotiam in healthy man following oral cefotiam hexetil. | cefotiam hexetil is a pro-drug of cefotiam available for oral administration. to evaluate cefotiam concentrations at the active site in skin and soft-tissue infections, drug levels in skin suction blister fluid (sbf), cantharides blister fluid (cbf) and serum were determined. six healthy subjects received oral cefotiam 400 mg as cefotiam hexetil. on an other day 200 mg was injected intravenously. following the oral dose, the bioavailability of cefotiam was 45.5%, and the maximum concentration in ... | 1990 | 2276386 |
| in vitro activity of hre 664, a penem antibiotic. | hre 664, a new penem antibiotic, inhibited 90% of escherichia coli, klebsiella, citrobacter diversus, proteus mirabilis, proteus vulgaris, salmonella, shigella, providencia, aeromonas, and morganella at less than or equal to 2 micrograms/ml but was considerably less active than cefotaxime, ceftazidime, and imipenem. it did not inhibit pseudomonas aeruginosa (mic greater than 128 micrograms/ml). hre 664 inhibited enterobacter spp., citrobacter freundii, and serratia marcescens at 1-8 micrograms/m ... | 1990 | 2279381 |
| induction of beta-lactamases: in vitro phenomena and clinical relevance. | an in vitro model was used to stimulate the plasma concentration-time curves for cefotaxime and cefoxitin as they would appear during treatment of patients with infections due to enterobacter cloacae and proteus vulgaris. the data showed that the induction of the chromosomally mediated beta-lactamase took place in both bacteria but that it had little or no effect on the bacterial kill. it is concluded that treatment failures in these settings were due to the selection of resistant mutants. | 1990 | 2282970 |
| the effect of protein and urine on uropathogen adhesion to polymer substrata. | uropathogenic adhesion was measured using a range of polymer materials with differing surface tension properties. experiments were carried out in the presence of phosphate buffered saline (controls), tamm horsfall protein (thp), and human urine with quantitation by image analysis. the results showed that thp did not bind to the polymer materials and therefore did not act as a receptor surface for type 1 fimbriated escherichia coli. however, the thp did interfere with adhesion by binding directly ... | 1990 | 2283351 |
| [microbiological and immunological indicators in patients with acute cholecystitis]. | the causative agents of acute destructive cholecystitis and wound complications are various pyogenic bacteria including staphylococci, enterococci, escherichia, proteus, and anaerobes among which certain varieties, serogroups, and phagocytes predominate. most bacteria, with the exception of anaerobes, are resistant to penicillin, streptomycin, and chlortetracycline but retain sensitivity to antibiotics of the neomycin series and other chemotherapeutic agents. in most patients with phlegmonous ch ... | 1990 | 2283745 |
| [initial experience with prophylactic proteus vaccine immunization in an emergency clinic]. | as early as the first 24 hours since a severe isolated locomotor trauma the patients were immunized with proteus vaccine. such vaccination is shown to stimulate the production of serum specific antibodies, to reduce contamination of the wound with gram-negative agents, to shorten hospital stay and healing of the wound versus subjects vaccinated with staphylococcal anatoxin and nonimmunized patients. | 1990 | 2283824 |
| [neonatal meningitis: observations on its etiology, mortality and sequelae]. | a retrospective study was carried out on all cases diagnosed with neonatal meningitis at the hospital infantil de méxico federico gómez. a rate of 9.6 cases per 1,000 discharged patients was found as well as 6.7% association with sepsis. in 50 of the cases analyzed, an etiologic agent was identified in 23 children; the main bacteria identified were escherichia coli (24%), klebsiella pneumoniae (14%), enterobacter (4%), proteus mirabilis and pseudomonas sp (2%), respectively. the mortality rate w ... | 1990 | 2285466 |
| the role of microorganisms in psoriasis. | the microflora of 297 psoriasis patients was extensively examined. throat, urine, and skin surfaces from scalp, ears, chest, face, axillary, submammary, umbilical, upper back, inguinal crease, gluteal-fold, perirectal, vaginal, pubis, penis, scrotal, leg, hands, feet, finger, and toenail areas were cultured for aerobic bacteria, yeast, and dermatophytes. antibody levels to streptococcal enzymes were performed (streptolysin-o, dnase-b, hyaluronidase, streptozyme). giemsa smears and koh preparatio ... | 1990 | 2285571 |
| severe infections treated with intravenous ofloxacin: a prospective clinical multicentre swiss study. | in this open prospective clinical trial of iv ofloxacin, 87 patients were treated for severe bacterial infections. overall results showed a clinical cure rate of 75% and 79/87 87 patients improved. 86% of causative organisms (all sensitive to ofloxacin) were eliminated. the best results were obtained in urinary tract infections where all 30 patients were clinically cured and 27 organisms (escherichia coli, group d streptococcus, proteus mirabilis and klebsiella pneumoniae) were eliminated. rapid ... | 1990 | 2286585 |
| [susceptibility of clinically isolated bacterial strains to imipenem/cilastatin sodium]. | in vitro antibacterial activities of imipenem/cilastatin sodium (imipenem) and other beta-lactams against clinically isolated 353 bacterial strains were investigated. the results obtained in this study are summarized as follows: 1. imipenem (ipm) showed potent antibacterial activities against gram-positive cocci such as staphylococcus aureus, staphylococcus epidermidis, enterococcus faecalis, streptococcus agalactiae. 2. ipm had inferior or equivalent antibacterial activities to beta-lactams aga ... | 1990 | 2287059 |
| [susceptibilities of clinical bacterial isolates to antimicrobial agents. a study mainly focused on imipenem. reported by the research group for testing imipenem susceptibility on clinical isolates]. | this study was conducted to investigate susceptibilities of clinical bacterial isolates to imipenem (ipm) and other antibacterial agents at 64 hospital laboratories throughout japan from september to december of 1988. in this study, identification and susceptibility testing were carried out at each laboratory and the tests were performed according to the disk dilution method recommended by nccls in which susceptibilities are classified into "s", "ms", "i" and "r". ipm showed markedly high in vit ... | 1990 | 2287060 |
| bacteria causing respiratory infections in children and their sensitivity to antibiotics. | the author lists the most frequent bacterial agents isolated from the nose and pharynx samples of children that visited the child health centre from 1983 to 1986. the gram-positive bacteria found most often were: staphylococcus aureus (44% in 1983, 40% in 1986). streptococcus pneumoniae (6% in 1983, 12% in 1986), and streptococcus haemolyticus of group "a" (14% in 1983, 19% in 1986). the isolated gram-negative bacteria were: e. coli (14%), klebsiella enterobacter (8%), and proteus species and ps ... | 1990 | 2291383 |
| [xanthogranulomatous pyelonephritis in children. apropos of 8 cases]. | eight pediatric cases of the diffuse form of xanthogranulomatous pyelonephritis are reported. these patients were selected among 17 with destruction of one kidney. clinical symptoms were suggestive of a tumor in some instances. however, an infectious etiology was strongly suggested by the presence of a renal lithiasis in seven cases (including five staghorn stones) and of a urinary tract infection in six cases (usually caused by a proteus). nephrectomy was performed in every case. | 1990 | 2291592 |
| in vitro activity against clinically important gram-positive and gram-negative bacteria of sulbactam, alone and in combination with ampicillin, cefotaxime, mezlocillin, and piperacillin. | the in vitro effects of the single agents, and the synergistic/antagonistic action of three different combinations of ampicillin (amp, cas 69-53-4), cefotaxime (ctx, cas 63527-52-6), mezlocillin (mez, cas 51481-65-3), and piperacillin (pip, cas 61477-96-1) with the beta-lactamase inhibitor sulbactam (sul, cas 68373-14-8) were determined against 675 gram-positive and gram-negative, both aerobic and anaerobic bacteria. all the combinations of sulbactam and the antibiotics (1: 1, 1:2 and 1:4) exhib ... | 1990 | 2291754 |
| in-vitro activity of cefpodoxime against 1834 isolates from domiciliary infections at 20 uk centres. | a total of 1834 non-copy, general practice or outpatient isolates were collected by 20 hospital laboratories within the british isles, and identified and tested for susceptibility to nine antimicrobial agents available by oral administration at one centre. against enterobacteriaceae cefpodoxime was the most active beta-lactam agent tested, the mic90s being: for escherichia coli 1.0 mg/l, for proteus mirabilis 1.0 mg/l, for citrobacter spp. 2.0 mg/l, and for enterobacter spp., serratia spp., morg ... | 1990 | 2292533 |
| changes in the antibiotic sensitivities of urinary pathogens, 1971-1989. | all urinary pathogens from general practice and hospital have been tested for sensitivity to a range of antimicrobial agents for the last 19 years. there have been marked changes during that time. in general practice there has been a considerable increase in the proportion of staphylococcal infections from 5.1% to a peak of 14.8% in 1982 and a more recent decline to 3.4%. there has also been a decrease in the proportion caused by proteus mirabilis, from 9.2% to 5.0%. similar, but smaller changes ... | 1990 | 2292543 |
| the effect of bacterial products on human fibroblast and keratinocyte detachment and viability. | an in vitro model has been developed to study the effect of soluble bacterial products on the viability and detachment of skin cell types utilized cultured grafts. microbial products prepared from clinical isolates of bacterial species which most commonly colonize burn lesions showed marked variation in their ability to detach and kill both keratinocytes and fibroblasts. all three isolates of acinetobacter spp. tested were effective in causing detachment and death of keratinocytes and fibroblast ... | 1990 | 2297501 |
| evolution of aromatic amino acid biosynthesis and application to the fine-tuned phylogenetic positioning of enteric bacteria. | a comprehensive phylogenetic tree for virtually the entire assemblage of enteric bacteria is presented. character states of aromatic amino acid biosynthesis are used as criteria, and the results are compared with partial trees based upon sequencing of 16s rrna, 5s rrna, and tryptophan leader peptide. three major clusters are apparent. enterocluster 1 possesses a gene fusion (trpg-trpd) encoding anthranilate synthase: anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase of tryptop ... | 1990 | 2298692 |
| proteus syndrome: course of a severe case. | we report on the course of a 4 1/2-year-old boy with proteus syndrome who was first described 3 years ago. details are given on the phenotypic changes, the complications of corrective surgery on tissue overgrowth, and the development of a mesothelioma of the tunica vaginalis of the testis. | 1990 | 2309770 |
| new plate medium for facilitated differentiation of salmonella spp. from proteus spp. and other enteric bacteria. | a new agar medium for the differentiation of salmonella spp. from other members of the family enterobacteriaceae is described. this medium exploits a novel phenotypic characteristic of salmonella spp.: the formation of acid from propylene glycol. this characteristic may be used in combination with a chromogenic indicator of beta-galactosidase to differentiate salmonella spp. from proteus spp. and the other members of the enterobacteriaceae. desoxycholate may be included in the plate medium as an ... | 1990 | 2310184 |
| purification and n-terminal analysis of urease from helicobacter pylori. | urease of helicobacter pylori (formerly campylobacter pylori) is believed to represent a critical virulence determinant for this species. ammonia generated by hydrolysis of urea may protect the acid-sensitive bacterium as it colonizes human gastric mucosa. an h. pylori strain, cultured from a gastric biopsy of a patient with complaints of abdominal pain and a history of peptic ulcer disease, was isolated on selective medium and cultured in mueller-hinton broth supplemented with 4% fetal calf ser ... | 1990 | 2318539 |
| manganese as a controlling factor in mixed cultures of lactobacillus plantarum and enterobacteriaceae. | addition of manganese, at levels of 50 ppm, to a liquid growth medium simulating adverse silage conditions had no effect on the growth or on the fermentation pattern of enterobacter cloacae and proteus vulgaris. yet, the manganese strongly enhanced the growth of lactobacillus plantarum. co-cultures of l. plantarum and e. cloacae or p. vulgaris were, by addition of manganese ions, significantly altered in the favour of the former. this finding can be of use in mixed cultures where enterobacteriac ... | 1990 | 2321928 |
| the in-vitro activity of ceftibuten against 475 clinical isolates of gram-negative bacilli, compared with cefuroxime and cefadroxil. | the in-vitro activity of ceftibuten was compared with cefuroxime and cefadroxil against 475 clinically-significant, epidemiologically-distinct isolates of gram-negative bacilli: 170 from blood, 212 from urine and 93 from a supplementary collection of multiply-resistant strains known to have resistance plasmids, to have caused sporadic or epidemic nosocomial infection, or both. ceftibuten mics ranged from 0.003 to greater than 32 mg/l, with a modal mic of 0.01 mg/l: 95% of all isolates had ceftib ... | 1990 | 2329100 |
| bacterial phospholipid analysis by fast atom bombardment mass spectrometry. | the structural analysis of naturally occurring bacterial phospholipids in mixtures by fast atom bombardment (fab) mass spectrometry are reported. the bacterial strains examined included several genera of actinomycetes, two strains of escherichia coli, and one strain each of proteus mirabilis and pseudomonas aeruginosa. fab mass spectrometry proved to be a useful tool for the structural identification of phospholipids in mixtures and provided stable pseudo-molecular ions and characteristic fragme ... | 1990 | 2331532 |
| epidemiology of antibiotic resistance in human isolates of enterobacteriaceae in sicily. | the authors have studied the antimicrobial susceptibility of 1073 clinical isolates of various genera of enterobacteriaceae (collected during the period july-december 1988) to ampicillin, piperacillin, cefotaxime, ceftazidime, ceftriaxone, aztreonam, imipenem, gentamicin, amikacin, netilmicin, norfloxacin, and ciprofloxacin. antimicrobial susceptibility was determined by bauer-kirby disk diffusion method. of 1073 tested bacteria, 704 (65.6%) produced beta-lactamase detectable by nitrocefin test. ... | 1990 | 2332782 |
| [microflora of suppurative inflammatory foci in surgical patients and its sensitivity to antibiotics]. | materials from 1134 patients with various surgical infections were tested. from the materials collected from purulent inflammatory foci 2137 cultures were isolated. many of them belonged to micrococcaceae (63.7 per cent). cultures belonging to enterobacteriaceae and streptococcaceae were isolated from 50.9 and 25.2 per cent of the patients respectively. isolates belonging to other families were less frequent: diphtheroids were isolated from 13.3 per cent of the patients and pseudomonas spp. were ... | 1990 | 2334244 |
| a medium for the selective isolation of edwardsiella ictaluri. | a selective medium, called edwardsiella ictaluri medium (eim), has been formulated for the isolation of edwardsiella ictaluri. the medium inhibits the growth of most gram-negative bacteria, except proteus sp., serratia marcescens and some isolates of aeromonas hydrophila and yersinia ruckeri. the bacteria that grow on the eim are easily differentiated from e. ictaluri based on colony morphology. the eim inhibits gram-positive bacteria with the exception of enterococci. the addition of fungizone ... | 1990 | 2338726 |
| the hpma hemolysin is more common than hlya among proteus isolates. | two different hemolysins, hpma and hlya, have been reported in proteus spp. to study the distribution of these hemolysins among proteus strains, isolates from various infections and normal feces were screened for hemolysin production. all 63 proteus mirabilis strains and 23 of the 24 proteus vulgaris strains produced a calcium-independent hemolytic activity detectable in cell-free supernatants. the calcium-independent activity was due to hpma; this activity correlated with the presence of hpma s ... | 1990 | 2341181 |
| cytotoxic activity of the proteus hemolysin hpma. | we previously showed that hpma is the hemolysin determinant most commonly found among proteus isolates. to assess the potential contribution of hpma to virulence, we first characterized the toxic activities of this hemolysin. hemolytic activity was present in total cell cultures and cell-free supernatants of proteus clinical isolates as well as escherichia coli containing cloned hpm genes. hpma also possesses cytotoxic activity which was detected by a chromium release assay against a variety of ... | 1990 | 2341182 |
| morganella morganii urease: purification, characterization, and isolation of gene sequences. | morganella morganii, a very common cause of catheter-associated bacteriuria, was previously classified with the genus proteus on the basis of urease production. m. morganii constitutively synthesizes a urease distinct from that of other uropathogens. the enzyme, purified 175-fold by passage through deae-sepharose, phenyl-sepharose, mono-q, and superose 6 chromatography resins, was found to have a native molecular size of 590 kilodaltons and was composed of three distinct subunits with apparent m ... | 1990 | 2345135 |
| septicemia in the elderly: incidence, etiology and prognostic factors. | a study on septicemia in the elderly (mean age 80.3 +/- 9.1 years) was carried out during 1982-85. a total of 184 episodes of bacteremia occurred in 175 patients (incidence rate 7.2%); 61% were attributed to community-acquired sepsis. gram-negative microorganisms accounted for 64% of all episodes and gram-positive for 30%. the overall mortality was 18.3%. using univariate analysis, significant factors associated with a high mortality were: hospital-acquired sepsis, respiratory infections as sour ... | 1990 | 2347685 |
| [statistical studies on bacteria isolated from urinary tract infections(report 5)]. | we examined bacteria isolated from urine of patients in our urological department from 1985 through 1987. a total of 2,566 strains were isolated from outpatients. they were 834 strains of gram-positive coccus (32.5%). e. coli (20.8%) was isolated most frequently, followed by proteus sp. (12.6%), enterococcus (9.6%), p. aeruginosa (6.7%), s. epidermidis (5.5%), and k. pneumoniae (3.7%) and others. a total of 784 strains were isolated from inpatients. they were 313 strains of gram-positive coccus ... | 1990 | 2353605 |
| chronic suppurative otitis media in sudanese patients. | a retrospective study was carried out to show the pattern of chronic suppurative otitis media in sudanese. patients with chronic suppurative otitis media were 43% of all patients with ear problem. the majority of patients affected by the disease were between 11-30 years with even distribution. males were affected more than females. the duration of symptoms varied between 0-20 years but most of the patients had the disease for over six years. pseudomonas aeruginosa, pseudomonas pyocyaneous and b. ... | 1990 | 2354676 |
| infected wounds and repeated septicemia in a case of factitious illness. | during 19 years an assistant nurse, now 35 years old, has been repeatedly treated for several malingered and self-induced disorders escalating to self-mutilation. an ulcer of her right leg never epithelialised in spite of various local treatments and surgical intervention. during repeated attacks of self-induced septicemia altogether 11 different bacterial species were isolated; on 8 occasions rhodococcus equi. the septicemias were successfully treated with antibiotics. the underlying psychiatri ... | 1990 | 2356446 |
| proteus syndrome (report of three cases). | | 1990 | 2357192 |
| proteus syndrome: report of a case with severe brain impairment and fatal course. | a patient with proteus syndrome is reported. he had hemihypertrophy, bilateral hypertrophy of the third fingers, skin anomalies, and varicosities, as well as mental retardation, seizures resistant to anticonvulsant treatment, and a very severe course with death at the age of 2 years. | 1990 | 2359106 |
| pericarditis due to salmonella dublin. | | 1990 | 2362900 |
| otogenic brain abscess with pneumocephalus. | | 1990 | 2365472 |
| [pneumonitis as a complication of low-dose methotrexate therapy in chronic polyarthritis]. | pneumonitis has been reported to be a rare complication of low-dose mtx treatment. this paper describes a 62-year-old male patient in whom clinically successful low-dose treatment was applied. after six months of treatment, a gradually progressive pulmonary symptomatology developed and abruptly deteriorated. radiological examination revealed interstitial and intra-alveolar densifications; functional analysis revealed partial respiratory failure. the histological finding of interstitial lymphocyt ... | 1990 | 2367474 |
| numerical analysis of electrophoretic protein patterns of providencia stuartii strains from urine, wound and other clinical sources. | eighty-six strains of providencia stuartii (mainly of human origin) were characterized by one-dimensional sds-page of cellular proteins. the strains came from various countries; 52 were from urine, 11 from wounds, five from blood (one of these also from urine), four from ear infections, two each from faeces and sputum, one from 'alimentation' and nine from unknown sources. the protein patterns, which contained 45 to 50 discrete bands, were highly reproducible. the patterns of 46 prov. stuartii s ... | 1990 | 2370236 |
| renal tubular acidosis and urinary tract infection. | | 1990 | 2370605 |
| [effect of immunization with proteus vaccine on the donor organism]. | | 1990 | 2373348 |
| [quantitative determination of urine bacteria in the diagnosis of urinary tract infections in children]. | bacteria counts in fresh, unstained, uncentrifuged urine specimens, using a phase-contrast microscope, magnification x 400, and a hemocytometer chamber, proved to be a very useful method not only of excluding (specificity 0.92) but also identifying urinary tract infection (sensitivity 0.90) in children. the presence of greater than 5/0.1 ml bacteria in the urine was taken as the threshold value. the evaluation of leukocyturia alone did not alter the sensitivity of the method, even when it was as ... | 1990 | 2377151 |
| rocky mountain spotted fever in new york state. | clinical and laboratory data provided in 214 rocky mountain spotted fever (rmsf) case reports received by the new york state department of health during 1977-1988 were analyzed to determine recent trends of this disease observed infrequently, but continuously, in new york state residents. age, sex, geographic exposure, onset, symptoms, laboratory test, treatment, and hospitalization data are presented. despite a 69% decrease of disease incidence from 1977 (0.368 cases per 10(5) population) to 19 ... | 1990 | 2378453 |
| urea protects helicobacter (campylobacter) pylori from the bactericidal effect of acid. | colonization of the stomach with helicobacter (campylobacter) pylori is common in patients with duodenal ulcer disease, which is known for its high acid secretion. although the bacterium is usually isolated by culture of a gastric biopsy specimen, viable organisms may sometimes be found in the acidic gastric juice. it was postulated that urease, by generating ammonia, protected h. pylori from acid. to test this hypothesis, the ph susceptibility of h. pylori, proteus mirabilis, and the urease-neg ... | 1990 | 2379775 |
| bacteremia and subcutaneous abscess caused by proteus penneri in a neutropenic host. | proteus penneri bacteremia and concomitant subcutaneous infection developed in a neutropenic patient with acute lymphocytic leukemia. the skin infection occurred while the patient was being treated empirically with cefoperazone and metronidazole. this case demonstrates the invasive potential of this microorganism in the proper setting. | 1990 | 2380386 |
| synchronous caverno-spongious thrombosis and fournier's gangrene. | fournier's or genito-perineal gangrene of the male genitalia typically spares the testis, urethra and deep penile components. it usually is polymicrobial and synergistic. to our knowledge, this is the first reported case in the literature with severe, deep, full penile thrombosis that caused a severe urethral stenosis and required later surgery. only proteus mb. could be isolated and gave rise to a disseminated intravascular coagulation syndrome that has probably accentuated the thrombotic penil ... | 1990 | 2383054 |
| direct introduction of a formamido group into the 7 alpha (6 alpha)-position of cephalosporins (penicillins). | a novel direct introduction of a formamido group into the 7 alpha (6 alpha)-position of cephalosporins (penicillins) was achieved by treatment of 7 beta (6 beta)-[(3,5-di-tert-butyl-4-oxo-2,5-cyclohexadien-1- ylidene)methylimino]cephem (penam) esters with n,n-bis(trimethylsilyl)formamide, followed by deblocking with girard reagent t to give the corresponding 7 alpha (6 alpha)-formamido-7 beta (6 beta)-amino derivatives. three 7 alpha-formamidocephalosporins were prepared by the conventional n-ac ... | 1990 | 2387776 |
| ambiguous genitalia in the proteus syndrome. | an 11-year-old girl was followed up since birth because of hemihypertrophy of the left leg and thigh, multiple pigmented nevi and subcutaneous tumors typical of the proteus syndrome. because of clitoromegaly and scrotal-like hypertrophy of the labia majora, she had an endocrine evaluation the results of which were normal. the findings are thought to represent local genital hypertrophy. ambiguous genitalia have to be added to the phenotype of the proteus syndrome. | 1990 | 2389808 |
| [comparison of bacteriostatic ability of oleum of perilla frutescens (l.) britt., cinnamomum cassia presl and nipagin a]. | a comparison of bacteriostatic ability has been carried out among oleum of perilla frutescens and cinnamomum cassia, benzoic acid and nipagin a. the result shows that the inhibiting effect of perilla frutescens and cinnamomum cassia on microorganisms inoculated and spontaneously contaminated is similar to or obviously superior to nipagin a and benzoic acid. | 1990 | 2390180 |
| pyodermas: an analysis of 127 cases. | in an analysis of 127 patients with pyodermas, 38 (30%) had primary pyodermas and 89 (70%) had secondary pyodermas. seventy-one percent (71%) of the primary pyodermas were due to staphylococcus aureus (s. aureus). five (5%) of the primary pyodermas were due to multiple organisms. among the patients with secondary pyodermas, 45% were due to s. aureus, 21% streptococci, 9% pseudomonas and 9% proteus species. forty-four percent (44%) of the secondary pyodermas were due to multiple organisms. s. aur ... | 1990 | 2393234 |
| the development of a transport and enrichment medium for campylobacter fetus. | a transport and enrichment medium was developed for campylobacter fetus. from inocula of between 10 and 35 organisms the medium was able to support the multiplication of 19 of 21 strains of c. fetus if the medium was incubated immediately after inoculation; when incubation was delayed for 3 days after inoculation, only seven of the 21 strains multiplied. from inocula of 100-350 organisms all 21 strains multiplied following immediate incubation, and 20 of 21 when incubation was delayed for 3 days ... | 1990 | 2397372 |
| cephalosporins to carbapenems: 1-oxygenated carbapenems and carbapenams. | the photo "wolff" rearrangement of readily available 2-diazoceph-3-em oxides (1) directly affords carbapen-2-ems, allowing a facile entry into a ring system previously accessible only by total synthesis, lengthly semisynthesis or fermentation. the chirality of the cephalosporin is accurately translated into the corresponding carbapenem. the resulting 1-oxocarbapenems (2) were selectively transformed through reduction into 1-oxygenated carbapenems and carbapenams (3 and 4, respectively). on micro ... | 1990 | 2404120 |