Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [alteration of the normal intestinal flora in human sucklings within the last 20 years]. | analyses of the feces-flora and the feces-ph of breastfed infants and of infants nourished with commercial formulae (ki-na, milasan) performed since 20 years were evaluated. in both regimens decreasing numbers of bifidobacteria could be remarked. the dominating position of this groups of bacteria was limited more and more. since 1971 the bifidobacterium biotype, characteristic of feces of breastfed infants could be proved no more. simultaneously germs of the e. coli-group and neonmycine-resisten ... | 1979 | 481569 |
| prophylaxis of recurrent urinary tract infection in female patients. efficacy of low-dose, thrice-weekly therapy with trimethoprim-sulfamethoxazole. | thirty-two women with recurrent urinary tract infections were treated after eradication of existing infections with a mixture of 40 mg of trimethoprim and 200 mg of sulfamethoxazole thrice weekly at bedtime for six months. six preadolescents received one half this dose. during 21.3 cumulative patient-years of prophylaxis, one infection due to streptococcus faecalis and one due to a sulfamthoxazole-and trimethoprim-sensitive escherichia coli occurred--an infection incidence of 0.1 per patient-yea ... | 1979 | 480642 |
| trimethylamine oxide: a terminal electron acceptor in anaerobic respiration of bacteria. | trimethylamine oxide (tmao) stimulated both the anaerobic growth rate and the growth yield of proteus nthc 153. the molar growth yield from glucose and pyruvate in tryptone/yeast extract medium doubled in the presence of tmao, and the organism grew anaerobically on the non-fermentable substrates l-lactate and formate when tmao was added to the medium. we conclude that tmao stimulated growth by serving as a terminal electron acceptor in an oxidative phosphorylation process. | 1979 | 479836 |
| selection of small-colony variants of enterobacteriaceae by in vitro exposure to aminoglycosides: pathogenicity for experimental animals. | small-colony variants of gram-negative genera of enterobacteriaceae were selected by in vitro exposure to gentamicin. these variants were shown to have decreased susceptibility in vitro to aminoglycosides. they were lethal for mice following intraperitoneal injection, with the ld50 (50% lethal dose) being the same as, or slightly less than, that for the parent organism. variants of strain no. 2401 of proteus mirabilis caused urinary tract infection in mice after implantation into their bladders. ... | 1979 | 479639 |
| morphological alterations in the mitochondria of amoeba proteus induced by uncoupling agents. | ultrastructural changes in mitochondrial morphology were observed in amoebae exposed to the uncoupling agents dinitrophernol (dnp), pentachlorophenol (pcp), and m-chlorocarbonyl cyanide phenylhydrazone (cccp). these alterations occurred with rapidity and were present before whole-cell activity changes could be detected. they included changes in profile shape and overall dimensions, matrix density changes, and alterations to the cristal membranes, so that distinction between control type i and ty ... | 1979 | 479326 |
| [first steps in the bacterial colonization of the digestive tract of neonates (author's transl)]. | meconium samples obtained from 14 children aged 18 to 51 h were subjected to a quantitative differential analysis. the meconium of one of the children (47 h old) was sterile; in those of the 11 infants aged less than 47 h the dominant flora was composed of either enterobacteria, mainly escherichia coli sensitive to usual antibiotics, or of streptococci. the genus acinetobacter constituted the dominant flora in one case only. staphylococcus, corynebacterium, clostridium (c. perfringens), bacteroi ... | 1979 | 475219 |
| storage of microtiter plates for antimicrobial susceptibility tests. | microdilution susceptibility tests are being performed routinely and in increasing numbers in many clinical laboratories. microtiter plates for these assays are usually prepared in large batches and stored frozen until needed. studies were performed to investigate the stability at -20c and at -70c of ampicillin, carbenicillin, ticarcillin, gentamicin, tobramycin, amikacin, chloramphenicol, and cephalothin, using enterobacter aerogenes, proteus mirabilis, proteus vulgaris, escherichia coli, pseud ... | 1979 | 474606 |
| [effect of immunization on the radioresistance of mice administered 137cs]. | 1979 | 472157 | |
| [nosocomial infections with providencia stuartii (proteus inconstans) (author's transl)]. | 48% of all isolates of providencia stuartii obtained within a period of one year, originated from the urine of catheterised patients, whereas another 37% were found in the respiratory tract of patients with intubation. the incidence of providenica stuartii correlated with the period during which iatrogenic measures had been applied, as well as with a preceding course with antibiotics. | 1979 | 467264 |
| antibiotics in pyelonephritis. | 1979 | 467068 | |
| fournier's gangrene. | twenty-five cases of gangrene of the scrotum and penis have been analysed. the anterior scrotum or the whole scrotum were the areas most frequently involved. the results of seminal analyses showed marked oligozoospermia during the infective period. haemolytic streptococcus was the most common organism. the aetiology of the disease is reviewed and "infective gangrene of the scrotum and penis" is considered to be a more suitable diagnostic label than fournier's gangrene. | 1979 | 466010 |
| [maternal lactation. ii. intestinal colonization in breast fed newborn infants]. | twenty-three low birth weight infants were studied to establish the role that breast milk plays in the intestinal colonization of the preterm infant, and in the control of epidemic diarrhea due to enteropathogenic e. coli, in nurseries. twelve of these case were fed breast milk in bottles, and eleven with "humanized" powder cow's milk (nan m.r.). bacteriologic studies of feces were performed daily during the first 18 days of life. in 5 cases given breast milk, and in 8 receiving cow's milk, stap ... | 1979 | 465174 |
| comparison between agar and broth minimum inhibitory concentrations of cefamandole, cefoxitin, and cefuroxime. | the in vitro susceptibility to cefamandole, cefoxitin, and cefuroxime of clinical isolates of streptococcus faecalis, klebsiella, and indole-positive proteus was assayed using minimum inhibitory concentration (mic) determinations in broth and on solid media. it could be demonstrated that the agar dilution mics obtained when s. faecalis was tested against cefuroxime and when indole-positive proteus strains were tested against cefamandole tended to be considerably lower than those obtained with th ... | 1979 | 464588 |
| [gastrointestinal tract microflora in nonspecific ulcerative colitis]. | the species and quantitative composition of the normal and conditionally pathogenic microflora of the stomach, the proximal portion of the small intestine, in material obtained by biopsy from the mucosa of this portion, and in feces was studied in 10 patients with non-specific ulcerative colitis. the study was made before and after treatment. before treatment in most of the patients gastric juice and the proximal portion of the small intestine were found to be greatly contaminated with microflor ... | 1979 | 463429 |
| microbiology of superficial and deep tissues in infected diabetic gangrene. | in the current study, it is shown that, in the lesions of diabetic gangrene, there are usually mixed flora of two or more organisms. the organisms isolated from the presenting lesion may only partially reflect the organisms found in the deep tissues. of the 58 cultures from the deep tissues, 11 of the isolates were anaerobes, but those anaerobes were never isolated as a pure culture. bacterial synergism probably plays a role in infected diabetic gangrene. maximizing the reduction of systemic inf ... | 1979 | 462355 |
| [clinical studies on pc-904 in biliary tract diseases (author's transl)]. | the clinical effects of pc-904, a new semisynthetic penicillin, were studied in patients with biliary tract diseases, and the results were as follows: 1) pc-904 showed an average peak serum level of 40.7 +/- 11.6 microgram/ml 2 hours after an intravenous drip infusion of 1 g of the agent. the biliary level showed a peak value of 126.5 +/- 85.4 microgram/ml 2 hours to 3 hours after the infusion. 2) isolated organisms from bile before the treatment were e. coli, klebsiella, proteus, pseudomonas, e ... | 1979 | 459091 |
| synthesis and antibacterial activity of 2-oxocephalosporins. | the first reported synthesis of 2-oxocephalosporin derivatives has been achieved via ozonolysis of the corresponding 2-methylenecephalosporins. the new cephalosporin derivatives showed some antibacterial activity against gram-positive bacteria, but the 2-oxo analogue of cephalothin was much less active than cephalothin itself. | 1979 | 458825 |
| spermatozoa repellent as a contraceptive. | early report by kopp et al. have demonstrated that p-nitrophenyl-glycerol (pnpg) is an effective antiswarming agent in proteus and that this inhibition may have been caused by pnpg interfering with the negative chemotaxis mechanism in the organism. with an inverted capillary assay, designed to test the motility response of rat epididymal spermatozoa to various suspending conditions including those exposed to chemical gradient, pnpg was shown in this study to exhibit an inhibitory effect at sligh ... | 1979 | 455977 |
| a ten-year retrospective study of sepsis in severely burned patients treated with or without silver sulfadiazinate. | three groups of extensive burn patients of the surgical intensive care unit (icu) have been compared: group i: twenty patients, who were treated locally without silver sulfadiazinate (1968-1970); group ii: the twenty first patients topically treated with silver sulfadiazinate (1970-1972); group iii: twenty similarly treated patients, with silver sulfadiazinate, six years later (1976-1977). the groups are statistically comparable. all bacteriological samples were computerized; the chi-square meth ... | 1979 | 451485 |
| bacteriology and treatment of chronic otitis media. | tympanocentesis was performed in 50 patients with chronic otitis media. pus was cultured aerobically and anaerobically. aerobes only were isolated from 21 patients, 3 had only anaerobes (peptococcus sp.) and 26 had both aerobes and anaerobes. there were 68 aerobic isolates. pseudomonas aeruginosa was recovered in 36 (72%). other aerobes commonly recovered included proteus sp. and staphylococcus aureus. there were 48 anaerobes isolated. anaerobic gram positive cocci were isolated in 24 instances. ... | 1979 | 449555 |
| [antibiotic sensitivity of the microflora isolated in ent diseases]. | sensitivity of beta-hemolytic streptococci of group a, streptococcus viridans, staphylococcus aureus, epidermal staphylococci, pneumococci, proteus and ps. aeruginosa isolated in 1975-1978 from patients with tonsillitis, otitis, sinusitis and other otorhinolaryngological diseases was studied with respect to 19 antibiotics. data on comparison of the antibiotic sensitivity of the microflora isolated from the patients with otorhinolaryngological diseases in 1964-1974 and 1975-1978 are presented. it ... | 1979 | 443782 |
| dissolution of a struvite nephrolith in a dog. | a large radiodense calculus in the left renal pelvis of a 22-month-old, male great dane disappeared one month following surgical removal of two struvite (magnesium ammonium phosphate) calculi from the right renal pelvis. the dog's urine likely became undersaturated with struvite for a sufficient period to permit dissolution of the renal calculus. several factors may have contributed to the decrease in urine struvite concentration, including eradication of a urease-producing proteus sp from the u ... | 1979 | 438042 |
| [in vitro testing of newer cephalosporins (author's transl)]. | the spectrum of activity of the newer cephalosporins is considerably wider and includes a number of gram-negative bacteria. test results using cephalothin as 'class disc' of a class of antibiotics is therefore no longer valid for the newer members. like cefazoline, all of the above-mentioned antibiotics are more effective against escherichia coli. cefuroxin and cefoxitin also display increased effectiveness against klebsiella, as do cefoxitin against serratia and indolpositive proteus species, a ... | 1979 | 437897 |
| pinocytosis and locomotion of amoebae: xii. dynamics and motive force generation during induced pinocytosis in a. proteus. | the mechanism of induced pinocytosis was investigated in amoeba proteus by light and electron microscopy. the application of nine different inducing substances revealed that pinocytotic channel formation, elongation, vesiculation, shortening and disappearance are the result of the successive or simultaneous action of both traction and pressure forces, which are produced by the contractile activity of a plasma membrane-associated layer of filaments ranging from a few hundred nm to several microme ... | 1979 | 436147 |
| [characteristics of the antibiotic sensitivity of nitrofuran--resistant gram-negative bacteria of clinical origin]. | 494 persons with various purulent inflammatory diseases were examined. gram-negative nitrofuran resistant organisms isolated from the clinical material were found in 22.9 per cent of the cases. representatives of enterobacteriaceae, klebsiella-enterobacter-serratia (26.8 per cent), proteus-providencia (16.8 per cent) and e. coli-arizona-citrobacter (16.1 per cent) predominated. pseudomonas (32.1 per cent) and acinetobacter (5.3 per cent) predominated among the aerobic gram-negative bacteria. sen ... | 1979 | 434799 |
| urolithiasis in children with spinal cord injury. | in the literature there is a paucity of references on urolithiasis in children with spinal cord injury. in this paper 28 cases of urolithiasis in 97 children with spinal cord injury are analysed. an attempt is made to evaluate the role of hypercalcemia, hypercalciuria and urinary tract infection in the genesis of these calculi. | 1979 | 431966 |
| xanthogranulomatous pyelonephritis (xgp): a local disease with systemic manifestations. report of 23 patients and review of the literature. | the clinical, pathological and radiographic findings of 135 cases of xanthogranulomatous pyelonephritis have been reviewed. it is a form of renal suppuration and obstruction most commonly seen in middle aged women although all ages and both sexes may be affected. there is no race predilection. gram-negative organisms are usually present and bilateral involvement has not been reported. the most common offending organism is proteus mirabilis. hepatic dysfunction is seen and appears to normalize wi ... | 1979 | 431402 |
| o serotyping of providencia stuartii isolates collected from twelve hospitals. | a collection of 829 isolates of providencia stuartii, mostly from urological specimens of patients in 12 hospitals, were o serotyped. hospitals varied in serotype distribution, but most isolates (97%) fell into one or another of 14 o types of p. stuartii. one type (o63) was found in 10 hospitals, and six types (o4, o17, o25, o52, o55, o56) were found in 5 or more hospitals. these seven types were more common than others and included 753 (91%) of the isolates. only four isolates agglutinated in p ... | 1979 | 429535 |
| urinary tract infection induced by intermittent urethral catheterization in dogs. | sterilized and unsterilized catheters were passed into the urinary bladders of 9 clinically normal adult male dogs once daily for 5 consecutive days, and the dogs were examined for up to 30 days to determine whether urinary tract infections developed. two dogs that were catheterized with clean unsterilized catheters (1 clinically normal dog and 1 dog given immunosuppressant drugs) developed persistent cystitis and pyelonephritis due to infection with proteus sp. one dog given immunosuppressant d ... | 1979 | 429232 |
| [the biliary excretion of azlocillin]. | the excretion of azlocillin into the human biliary tract was investigated in 8 patients with a t-tube in the common bile duct after intravenous injection of 2 g. samples of serum and common duct bile were assayed from 15 min to 12 hours after injection. biliary tract levels generally run parallel to serum levels but were about 15 times higher than those. peak levels in t-tube bile averaged 1137 mg/l 60 to 90 min after administration. 12 hours after administration there were still mean concentrat ... | 1979 | 428879 |
| bl-s786 (ceforanide), a new parenteral cephalosporin: in vitro studies. | bl-s786 (ceforanide) is a new cephalosporin which showed broad-spectrum activity in vitro against 453 clinical isolates. at a concentration of 3.12 mug/ml, it inhibited greater than 75% of isolates of escherichia coli, klebsiella spp., proteus mirabilis, staphylococcus aureus, streptococcus pyogenes, and streptococcus pneumoniae. essentially no activity was observed against isolates of serratia marcescens, and only minimal activity was observed against enterobacter spp. its activity was directly ... | 1979 | 426520 |
| hr 756, a new cephalosporin active against gram-positive and gram-negative aerobic and anaerobic bacteria. | the in vitro activity of hr 756, 7-[2-(2-amino-4-thiazolyl)-2-(z)-(methoximino)acetamido] cephalosporanic acid, was investigated against 659 isolates. hr 756 inhibited neisseria and haemophilus species at concentrations similar to those needed with ampicillin. it inhibited beta-lactamase-producing n. gonorrhoeae and h. influenzae. hr 756 was the most active compound tested against members of the enterobacteriaceae, inhibiting most isolates of escherichia coli, klebsiella pneumoniae, proteus mira ... | 1979 | 426518 |
| cefatrizine activity compared with that of other cephalosporins. | cefatrizine, a new orally administered cephalosporin, was tested against 400 clinical isolates. cefatrizine had excellent activity against gram-positive cocci, inhibiting all except enterococci at minimal inhibitory concentrations below 1 mug/ml. cefatrizine inhibited the majority of escherichia coli, klebsiella pneumoniae, proteus mirabilis, and salmonella at concentrations below 12.5 mug/ml. although cefatrizine was not hydrolyzed by many beta-lactamases, it did not inhibit a number of strains ... | 1979 | 426514 |
| tetracycline-induced aplastic anemia. | a 54-year-old man developed mild renal insufficiency after treatment with gentamicin and cephalothin. he then received tetracycline for eight days, 500 mg orally four times daily, for a total dose of 15 gm. twelve days after discontinuation of the drug, a severe but reversible aplastic anemia developed. we propose that bone-marrow-toxic concentrations of tetracycline resulted from the preexisting renal insufficiency. because of the temporal relationship between tetracycline administration and ap ... | 1979 | 424834 |
| [effect of neuraminidase on phagocytosis activity in amoeba proteus (author's transl)]. | 1979 | 421771 | |
| prostatitis in the rat. | a high incidence of spontaneous, non-acute, age-dependent prostatitis was observed in the lateral prostate of copenhagen rats and wistar rats. the lumen of infected acini was filled with polymorphonuclear leucocytes, shed epithelial cells and cell residues. epithelial cells lining such acini showed degenerative changes. lymphocytes and macrophages were seen in the stroma. a histochemically observed increase in acid phosphatase and beta-glucuronidase activity in affected epithelial cells may indi ... | 1979 | 419384 |
| heterologous transfection with bacteriophage phix174 dna: and improved system. | a highly efficient and much more reproducible system for the heterologous transfection of several kinds of gram-negative bacterial spheroplasts with bacteriophage phix174 dna was established. by mild washing of the speroplasts, the efficiency of transfection of all non-host heterologous bacterial species tested increased one or more orders of magnitude in producing the progeny phages and/or the infectious intermediates. using the improved heterologous transfection systems, it has become clearer ... | 1978 | 418813 |
| [investigations on the antimicrobial activity of amin-aldehyde-condensates. 2. communication: unsymmetrically substituted animals of formaldehyde (author's transl)]. | in the scope of our research about the antimicrobial activity of aldehyde-amin-condensates a number of partly new unsymmetrically substituted animals was synthesized by reaction of formaldehyde with different secondary amines. structures and physically constants are shown in the tables 1 and 2. the antimicrobial activity is demonstrated by the results of the disktest (table 3), of the minimal inhibition concentration (mic, table 4) and the suspension and area disinfecting tests following the met ... | 1977 | 416627 |
| antibacterial activity of sisomicin. | a study of the in vitro antibacterial activity of a new aminoglycoside, sisomicin, is reported. the results show no significant differences between the activity of sisomicin and gentamicin. | 1978 | 415913 |
| [aggravation of experimental dysentery in mice and acceleration of the process of multiplication of pathogenic and conditionally pathogenic bacteria under the effect of yeast rna]. | simultaneous infection of mice with sh. flexneri subtype 2a, culture, with various doses of rna sodium salt (narna) or administration of the preparation 3 hours prior to or 6, 12, and 18 hours after the infection was accompanied by aggravation of the experimental infection in mice. this was expressed in a greater number of animals which contracted the disease and died, and in increased blood and peritoneal exudate microbiol density. the same processes were noted in mice infected with equal doses ... | 1978 | 415460 |
| [recognition of bacterial infections in newborns by measuring specific antibody-titres (author's transl)]. | antibodies were measured in 172 unselected neonates against mixed polyvalent antigens derived from e. coli, klebsiella, ps. aeruginosa and proteus spp. respectively, using a modification of the indirect haemagglutination technique according to neter. 120 of these neonates with no evidence of infection served as controls. 6 out of 8 children with proven e. coli septicaemia had either raised titres or significant rises in titre. five further neonates with septicaemia, four due to klebsiella and on ... | 1978 | 415229 |
| comparative immunological studies on arylsulfatase in bacteria of the family enterobacteriaceae: occurrence of latent arylsulfatase protein regulated by sulfur compounds and tyramine. | the arylsulfatases of 21 strains of the family enterobacteriaceae were compared by measuring their enzymatic activities and immunological reactivities. enzyme formation under repressing, nonrepressing, and derepressing conditions was tested. antiserum prepared against pure arylsulfatase from klebsiella aerobgenes w70 was tested against the enzyme extracts from the strains using double diffusion, quantitative precipitation, and immunoelectrophoresis. no close relationship was found between arylsu ... | 1978 | 415041 |
| chemotactic activity of l-forms and mycoplasma. | l-forms of streptococcus faecalis, escherichia coli and proteus mirabilis showed significantly less chemotactic activity for normal human leucocytes than did parent bacterial forms which were strongly chemotactic. mycoplasma pneumoniae and mycoplasma hominis did not demonstrate chemotactic activity. | 1977 | 414709 |
| dimethyl sulfoxide as an electron acceptor for anaerobic growth. | the isolation from lake mud of a bacterium which can use dimethyl sulfoxide (dmso) as an electron acceptor for growth is described. the isolate, called strain dl-1, was a small, gram negative, non-motile spiral. the sole product of dmso reduction was dimethyl sulfide (dms). other electron acceptors used by the isolate included sulfite, thiosulfate, elemental sulfur, methionine sulfoxide, tetramethylene sulfoxide, nitrate, and oxygen (microaerophilically). sulfate was not reduced and could not ev ... | 1978 | 414686 |
| [recommendations for the testing and the evaluation of the efficacy of chemical disinfectant procedures (author's transl)]. | 1977 | 414483 | |
| [spinal cord influences on immune responses demonstrated following interruption of the spinal cord as a result of injury]. | specific and nonspecific immunity reactions were studied in dynamics in 126 patients with injury to the spinal cord, in 162 healthy persons (controls), and in 30 persons who had suffered injury to other organs. the serum agglutinins against the causative agents of infection of the urinary system (colibacillus, proteus, enterococcus) and c-reactive protein were studied. phases were revealed in the course of the immunologic reactions depending on the neurodynamics of the damaged spinal cord. the c ... | 1977 | 414445 |
| studies of vesicoureteral reflux: a review of work in a primate model. | studies of vesicoureteral reflux in a primate model were reviewed. reflux was found to be uncommon in adults but frequent in infants, suggesting that maturation of the ureterovesical junction occurs. repeated bladder infections did not prevent this maturation. infection did not cause reflux unless the junction was only marginally competent. reflux prolonged urinary tract infection in the infant, but in the adult monkey it did not. | 1978 | 414361 |
| the formation of germtubes by candida albicans, when grown with staphylococcus pyogene, escherichia coli, klebsiella pneumoniae, lactobacilius acidophilus and proteus vulgaris. | the formation of germtubes by twelve clinical isolates of c. albicans was studied in human serum containing per millilitre 10(3) to 10(9) organisms as: staphylococcus pyegene, escherichia coli, klebsiella pneumoniae, lactobacillus acidophilus and proteus vulgaris. all the five bacteria inhibited formation of germtubes by c. albicans at all concentrations and the percent germtube formed diminished with increasing concentration of the bacteria. lactobacillus acidophilus inhibited the formation of ... | 1977 | 414139 |
| p-nitrophenylglycerol--a superior antiswarming agent for isolating and identifying pathogens from clinical material. | the antiswarming agent p-nitrophenylglycerol (pnpg) has been found invaluable for the recognition and isolation of pathogenic bacteria from specimens contaminated with swarming strains of proteus spp. pnpg is cheap, stable and non-toxic. all strains tested grew well in its presence and produced characteristic morphology. pnpg was without effect on the results of a variety of identification tests performed directly on colonies from media containing pnpg. this permitted identification without the ... | 1978 | 413924 |
| lipoquinones of some bacteria and mycoplasmas, with considerations on their functional significance. | in a comparative study the lipoquinones of some chemoorganotrophic, facultatively aerobic bacteria, and representative acholeplasma, mycoplasma, spiroplasma, and thermoplasma strains were investigated. the quinones were partly purified by preparative thin layer chromatography of lipid extracts, and characterized by their difference spectra (reduced minus oxidized) and rf values. respiring bacteria expectedly contained benzoquinones and/or naphthoquinones in micromolar concentrations whereas some ... | 1977 | 413478 |
| [development of resistance. problems of chemotherapy in urology]. | 1977 | 413268 | |
| plantar ulcers with osteomyelitis underneath. a bacteriological study. | 39 consecutive cases of plantar ulcers with underlying chronic osteomyelitis admitted in the sacred heart hospital during 1975/1976 were studied for the infecting organisms and their sensitivity to easily available antibiotics. single organism was iasolated in only 10 cases, the infection in the rest being a mixed one. the commonest organisms were staphylococcus, streptococcus and proteus mirabilis. in a few cases pseudomonas and e-coli were also isolated. chloramphenicol was the most effective ... | 1977 | 413005 |
| a comparative investigation of the bactericidal and fungicidal effects of three phenolic disinfectants. | 1977 | 412825 | |
| nocardicin a, a new monocyclic beta-lactam antibiotic iv. factors influencing the in vitro activity of nocardicin a. | factors influencing the in vitro antimicrobial activity of nocardicin a against pseudomonas aeruginosa and proteus mirabilis were investigated. sodium chloride was identified as a major inhibitor. some of the amino acids, sugars and divalent cations were found to be minor inhibitors. the presence of potassium phosphates enhanced nocardicin a activity against p. aeruginosa, but antagonized the activity against p. mirabilis. | 1977 | 412824 |
| nocardicin a, a new monocyclic beta-lactam antibiotic iii. in vitro evaluation. | nocardicin a, a new monocyclic beta-lactam antibiotic, exerts a comparatively potent antimicrobial activity against gram-negative organisms, especially pseudomonas aeruginosa, the indole-positive and indole-negative proteus groups (except pr. morganii), serratia marcescens and the neisseria groups. the in vitro antimicrobial activity of nocardicin a against clinical isolates of ps. aeruginosa was about twice that of carbenicillin. the mean mics of nocardicin a for pr. mirabilis, pr. rettgeri and ... | 1977 | 412823 |
| antimicrobial synergism in the therapy of gram-negative rod bacteremia. | to determine if antimicrobial synergism might affect the results of treatment of gram-negative rod infections, 444 bacteremias from 1972 through 1974 were studied. on these, 173 were treated with two antibiotics to which the infecting organisms were sensitive. clinical responses were observed in 80% of 83 cases where antibiotic activity was synergistic, as defined by a minimum inhibitory concentration (mic) of each antibiotic in combination being one-fourth or less than the mics of individual dr ... | 1978 | 412648 |
| [in-vitro effect of tobramycin]. | 1977 | 412333 | |
| [clinical and pharmacological evaluation of s-6436 (long acting preparation of cephalexin) in urinary tract infections (author's transl)]. | 1977 | 411848 | |
| [selective effect of propolis in the isolation of listeria monocytogenes (author's transl)]. | propolis is a substance produced by honeybees. it is inhibitory to some bacteria species, mainly gram-positive bacteria, but less inhibitory to listeria monocytogenes (l.m) than to the other gram-positive bacteria tested. in order to obtain selective growth of l.m. from contaminated samples, the effect of propolis in plating media and broths on various strains of bacteria was examined. table i shows the effect of increasing concentrations of propolis in tryptose-agar (ta). l.m. tolerated higher ... | 1977 | 411111 |
| [azlocillin--a new penicillin against pseudomonas aeruginosa and other gram-negative bacteria]. | 1977 | 410735 | |
| [seroepidemiological investigations on the prevalence of rickettsial antibodies in man in the federal republic of germany (author's transl)]. | 1,600 random serum samples from inhabitants of hesse were investigated for rickettsial antibodies by complement fixation test. antibodies were found in 19 samples (1,2%) against rmsf-group antigen with titers between 1:10 and 1:640. these results confirm recent reports on natural foci of such rickettsial infections in the federal republic of germany. antibodies against rickettsia of the typhus-group or coxiella burnetii could not be detected by the complement fixation reaction. none of the sera ... | 1977 | 410727 |
| [antibiotic sensitivity of the causative agents of suppurative surgical infection]. | sensitivity of 1492 strains of the causative agents of the surgical purulent infections, i. e. pathogenic staphylococcus, proteus, ps. aeruginosa and e. coli to benzylpenicillin, streptomycin, levomycetin, tetracycline, erythromycin, oleandomycin, monomycin, kanamycin, novobiocin, ampicillin, oxacillin, ceporin, gentamicin and rifampicin was studied. gentamicin was most active against all the bacterial species tested. the staphylococci were in addition sensitive in a high percentage of the cases ... | 1977 | 410359 |
| [studies on the activation of humoral defense factors against bacteria in larvae of the wax moth galleria mellonella l]. | the change of lysozyme activity in the hemolymph of the wax moth larvae caused by vaccination is influenced by the size and the dose of the injected particles. the rate of incorporation of those particles into phagocytes has no effect on this process. the change of lysozyme activity correlats negatively with the amount of granulocytes after vaccination. there were no correlations with the amount of other types of the hemocytes, neither with the resistance of the larvae against pseudomonas aerugi ... | 1977 | 410207 |
| a collaborative study on the repeatability and the reproducibility of the dutch standard-suspension-test for the evaluation of disinfectants. | 1977 | 410202 | |
| [a new type of ointment base: investigations on its antimicrobial properties (author's transl)]. | a new ointment base (pen 32) consisting of polyalcohols prevents the growth of bacteria and fungi in concentrations above 25% (mg/mg). in a concentrated form the ointment base exhibited excellent bactericidal and fungicidal effects in vitro. this property enables the ointment base to be employed without preservatives. | 1977 | 410167 |
| [the basic studies on chemotherapy in urinary tract infection due to organisms with resistance to antibiotics (author's transl)]. | 1977 | 409865 | |
| patterns and mechanisms of emergence of resistance to amikacin. | emergence of gram-negative bacilli resistant to amikacin occurred in five of 96 patients treated. three of the five instances were associated with clinical failure and arose during therapy for an infection caused by a pathogen also susceptible to gentamicin. the other two episodes were associated with colonization. the enzyme aminoglycoside-6'-acetyltransferase, which inactivates amikacin, was found in serratia marcescens. decreased permeability to amikacin was shown in four isolates of pseudomo ... | 1977 | 409785 |
| [morphologic characteristics of spheroid elements in a culture of bacterial l-forms according to scanning electron microscopy findings]. | the authors studied stable l-cultures of proteus valgaris, bac. subtillis, staphylococcus aureus, streptococcus pyogenes of group a, and also unstable cultures of the l-forms of proteus vulgaris and proteus vulgaris culture at the stage of spheroplasts. spheroid cells proved to appear at the stage of spheroplasts, prevailed at the log phase in stable and unstable l-cultures, but were less frequent at the stationary phase. cross section of l-colonies showed that they were located at the surface. ... | 1977 | 409012 |
| [suprapubic puncture of the bladder within the scope of bacteriological urine diagnosis in gynecological-obstetrical patients]. | technology, evidence as well as indications and contraindications of the suprapubic bladder puncture are shown from a gynecological and obstetrical point of view. the bacteriological result of urine obtained by puncture from 476 women has been compared with that obtained subsequently by midstream voiding. it was proved statistically that bladder puncture yielded less positive results than midstream voiding. in 8.4 per cent of the cases there was a positive voided midstream urine culture with pat ... | 1977 | 409001 |
| effect of systemic antibiotics on the microbial flora of the external ear canal in hospitalized children. | the effect of antibiotic therapy and hospitalization on the external ear canal flora was investigated in 131 children. fifty-eight percent of the patients receiving antibiotic therapy had gram-negative bacilli or yeasts in their external ear canal, compared with 17% of the patients who were hospitalized for ten days or longer and only 3% of the patients who were hospitalized for short periods. antibiotic therapy is the major factor in determining the colonization rate of the external ear canal w ... | 1977 | 408786 |
| comparative studies of rna polymerase subunits from various bacteria. | the molecular structure of rna polymerases from escherichia coli, salmonella typhimurium, salmonella anatum,serratia marcescens, aerobacter aerogens, proteus mirabilis and bacillus subtilis were compared based on:i) inhibition of the enzyme activity by treatment with antibodies against e. coli rna polymerase subunits;ii) analysis of antibody precipitates by sodium ododecyl sulfatepolyacrylamide gel electrophoresis; and iii) analysis of antibody precipitates by urea-isoelectrofocusing followed by ... | 1977 | 408600 |
| activation of complement by opportunist pathogens and chemotypes of salmonella minnesota. | washed cells of staphylococcus aureus, escherichia coli, proteus mirabilis, pseudomonas aeruginosa, and salmonella minnesota chemotypes (s, rb, and re) were tested for their ability to activate the alternative complement pathway (acp). parameters of acp activation were (i) conversion of c3 in 10 mm ethyleneglycol-bis-(beta-aminoethyl ether)-n,n1-tetraacetic acid-treated human serum supplemented with 2.5 mm mgcl2, (ii) lysis of glutathione-treated human erythrocytes in the presence of human serum ... | 1977 | 408268 |
| [subinhibitory concentrations of antibiotics. effects on morphology and growth (author's transl)]. | experiments with subinhibitory concentrations of antibiotics revealed certain effects that had not been observed at higher concentrations. two different effects are described: morphological changer and inhibition of growth. the expression minimum antibiotic concentration (mac) has been shown to be of both theoretical and practical value. it has served to make plain the differences between the effects of various antibodies that were not observed at the mic. the ratio mac/mic could be be of import ... | 1977 | 406590 |
| [fulminat courses of sepsis in newborn infants and infants]. | 1977 | 406522 | |
| studies on quinoline derivatives and related compounds. 5. synthesis and antimicrobial activity of novel 1-alkoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids. | a series of novel 1-alkoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids was synthesized and screened as antimicrobial agents. the most active compounds in vitro against gram-negative microorganisms and staphylococcus aureus were 1,4-dihydro-1-methoxy-6,7-methylenedioxy-4-oxo-3-quinolinecarboxylic acid (22), 1,2,6,9-tetrahydro-6-methoxy-9-oxofuro[3,2-f]quinoline-8-carboxylic acid (30, and 2,3,6,9-tetrahydro-6-methoxy-3-methyl -2,9-dioxothiazolo [5,4-f]quinoline-8-carboxylic acid (34). these comp ... | 1977 | 406396 |
| clinical and laboratory study of tobramycin in the treatment of infections due to gram-negative organisms. | tobramycin, an aminoglycoside antibiotic, was used to treat 52 infections due to gram-negative organisms in 51 patients. complicated urinary tract infections, bacteremia and pyelonephritis accounted for 80% of the infections. the rate of immediate satisfactory response was 79%. during therapy with tobramycin, resistant organisms emerged in four patients--two pseudomonas aeruginosa and two escherichia coli strains. there were four superinfections with tobramycin-resistant providencia sp. in four ... | 1977 | 406032 |
| laboratory evaluation of pirbenicillin, a new penicillin with antipseudomonal activity. | 1977 | 405364 | |
| synergy and rifampicin. | 1977 | 405361 | |
| mode of action of the protein, sp127, which enhances the activity of macrolide antibiotics against pseudomonas aeruginosa. | antibiotics, the activity of which enhanced against pseudomonas aeruginosa by sp127, were restricted to the basic macrolide antibiotics such as erythromycin, maridomycin and oleandomycin, the neutral macrolide antibiotics such as lankamycin and lankacidin c, vancomycin and enramycin. synergistic activity of sp127 with the above antibiotics was found against pseudomonas aeruginosa and several strains of escherichia coli, but not against proteus vulgaris and macrolide-resistant staphylococcus aure ... | 1977 | 405356 |
| skin changes in short-bowel syndrome. kwashiorkor-like syndrome. | an infant with short-bowel syndrome developed flexural desquamation and "enamel paint" skin in pressure-bearing areas. hyperalimentation with amino acid and lipid solution was unsuccessful in correcting the malnutrition and skin changes. | 1977 | 404970 |
| antibacterial effects of metrizoate and metrizamide on bacterial growth in vitro. | urinary pathogens were exposed in vitro to isopaque and amipaque in concentrations of 100 mg i/ml and 260 mg i/ml. both contrast media in the higher concentration had a slight or negligible bacteriostatic effect on some of the test bacteria. no bactericidal effect was detected. consequently, radiography of the urinary tract with these two media in the concentrations mentioned does not interfere with the culturing of bacteria from urine samples. | 1977 | 404846 |
| [dynamics of the establishment of intestinal microflora in healthy full-term newborns]. | a study was made of the dynamics of establishment of the intestinal microflora in 79 healthy mature neonates born of healthy mothers. a total of 223 bacteriological examinations were conducted. a stable prevalence of bifidobacteria over the aerobic portion of the intestinal biocenosis occurred in all the children from the 8th day after birth. along with this the following bacteria were continuously present in the intestine: lactic bacilli and streptococci e. coli, enterococci and staphylococci; ... | 1977 | 404808 |
| [diagnosis of bacterial infections of the urinary tract]. | the aetiopathogenesis of bacterial infections of the urinary ways and the techniques used to isolate and identify the bacteria present in the urine are considered. the following aspects are covered: 1) introduction (clinical microbiology); 2) urine and bacterial multiplication; 3) diagnostic techniques in urinary way infections; 4) urine leucocyte count; 5) urine bacteria count; 6) guidelines for applying bacteriological research; 7) recurrent infections of the urinary ways; 8) diagnosis of the ... | 1977 | 404596 |
| sensitivity of gram-negative bacteria to six aminoglycoside antibiotics. | an in vitro study of the susceptibility of 201 newly isolated strains of gramnegative bacteria to six aminoglycoside antibiotics (kanamycin, amikacin, gentamicin, tobramycin, sisomicin and netilmicin) was performed by the twofold dilution method in fluid medium. both the minimal inhibitory concentration and the minimal bacteridical concentration were determined. overall, tobramycin seemed the most effective of the drugs studied. netilmicin, the new derivative from sisomicin, compared favourably ... | 1977 | 404254 |
| [reservoir for bacteria of urinary tract infections in urologic patients (author's transl)]. | many infections of the urinary tract, especially after surgical treatment are nosocomial infections. the etiological bacteria could only be found in the urine of the infected patients and in the faecal flora of nearly 40% of all stationary patients. the so called "problem bacteria": klebsiella, proteus rettgeri, pseudomonas showed increasing drug resistance during the observed period between 1972-1975. the bacteria isolated from the faecal flora also showed multiple drug resistance. thus we conc ... | 1977 | 404234 |
| [sensitivity of the wound microflora of oncological patients to some new antibiotics]. | sensitivity of the microflora of the oncological patients' wounds to the new antibiotics, such as gentamicin, kanamycin, oxacillin, ampicillin and lincomycin was studied with the help of the disc method. the discs with the above antibiotics were prepared under laboratory conditions in accordance with the respective instructions in the who. sensitivity of 429 bacterial cultures, including 98 cultures of pathogenic staphylocci, 45 cultures of enterococci, 43 hemolytic streptococci, 143 cultures of ... | 1977 | 403854 |
| [problems of ambulatory pharmacotherapy. 8. a model for antibiotik-rank series in urinary tract infections]. | 1977 | 403689 | |
| immunochemical comparison of phosphoribosylanthranilate isomerase-indoleglycerol phosphate synthetase among the enterobacteriaceae. | the bifunctional enzyme of the tryptophan operon, phosphoribosylanthranilate isomerase-indoleglycerol phosphate synthetase (prai-ingps;ec 4.1.1.48), was characterized by an immunochemical study of six representative members of the enterobacteriaceae: escherichia coli, salmonella typhimurium, enterobacter aerogenes, serratia marcescens, erwinia carotovora, and proteus vulgaris. prai-ingps was purified from e. coli, and antisera were prepared in rabbits. these antisera were utilized in quantitativ ... | 1977 | 403178 |
| [toxicity of bacterial polysaccharides (a review of the literature)]. | 1977 | 402887 | |
| [antibiotic sensitivity of proteus, pseudomonas pyocyanea and staphyloccoci isolated from scleroma and ozena patients]. | antibiotic sensitivity of 292 strains of proteus, 60 strains of ps, aeruginosa, 309 strains of s. aureus and 88 strains of s. epidermidis isolated from the upper respiratory tract of patients with scleroma and ozena was studied. the cultures of pr. mirabilis were sensitive to aminoglucosides (54.9-96.2 per cent) and pr. morganii were sensitive to levomycetin (81.5 per cent) and neomycin (92.6 per cnet). sensitivity of pr. vulgaris and pr. morganii was reliably higher (p less than 0.001) than tha ... | 1977 | 402886 |
| [antibacterial activity of rifampicin against the causative agents of suppurative, septic diseases]. | the antibacterial activity of rifampicin was studied in comparison with other antibiotics with respect to clinical strains isolated from cases with various purulent inflammatory processes caused by staphylococcus, e. coli, ps. aeruginose, proteus. the aim of the study was to define the role of rifampicin in the treatment of the above infections. no rifampicin resistant strains were found among staphylococci belonging to the phenotype carrying the determinants of resistance to 2-8 antibiotics. ri ... | 1977 | 402885 |
| in vitro activity of netilmicin, gentamicin, and amikacin. | the in vitro activity of netilmicin (sch 20569), a new semisynthetic derivative of gentamicin, was compared with that of gentamicin and amikacin. one hundred and ninety-two clinical isolates of enterobacteriaceae, pseudomonas aeruginosa, and staphylococcus aureus were tested using both agar and broth dilution techniques. netilmicin was comparable to gentamicin, with the following exceptions: (i) for serratia marcescens and p. aeruginosa, gentamicin was more active than netilmicin; (ii) all strai ... | 1977 | 402104 |
| the metabolism of starch, glucose, amino acids, purines, pyrimidines and bacteria by the rumen ciliate polyplastron multivesiculatum. | the large rumen ciliate protozoon polyplastron multivesiculatum grown in vitro engulfed a wide range of bacteria (from a population density of 10(9) bacteria ml(-1)) at a rate of 1500 to 137000 bacteria h(-1) protozoon(-1). no evidence was found for the preferential engulfment of bacteria of rumen origin. except for proteus mirabilis none of the bacteria were digested with the liberation of soluble materials into the medium. glucose and amino acids were taken up rapidly by p. multivesiculatum co ... | 1977 | 401868 |
| evolution of sensitivity to fosfomycin at jimenez diaz foundation. | the sensitivity to fosfomycin of more than 8,000 strains of bacteria isolated from products recevied by the laboratory between 1972 and 1974 has been studied. some were studied by the dilution technique in a solid medium and the remainder was studied by diffusion. a single 50-mug disc was used and the strains inhibited by concentrations of less than 64 mug/ml or with inhibition halos of 15 mm diameter or more were considered sensitive. it is clear from this study that there are no significant ch ... | 1977 | 401722 |
| fosfomycin, antimicrobial activity in vitro and in vivo. | antibacterial activities of fosfomycin were investigated both in vitro and in vivo for the purpose of comparative evaluation on its fundamental properties with other antimicrobial agents. the mic was determined with nutrient agar (difco) inoculated with one loopful of 1,000-fold dilution (about 10(6) cells/ml) of bacterial suspension cultured overnight in nutrient broth. this substance showed antibacterial activity to most gram-positive and gram-negative bacteria, being strongest to enterobacter ... | 1977 | 401721 |
| r plasmids coding for gentamicin, tobramycin, and carbenicillin resistance in serratia, klebsiella and escherichia coli strains from a single clinical source. | serratia marcescens, klebsiella sp. and escherichia coli strains bearing transferable resistance to aminoglycoside antibiotics, namely, gentamicin, tobramycin, kanamycin, streptomycin, lividomycin, and carbenicillin, as well as to a series of more classical drugs, began to emerge in materials from the frankfurt university hospital. plasmids from serratia, klebsiella, and e. coli exhibit a broad host range in that they are transferable to e. coli, proteus mirabilis and salmonella typhimurium rece ... | 1977 | 401718 |
| susceptibility to fosfomycin of hospital strains isolated in nantes (france). frequency of mutation to resistance. | susceptibility of 760 bacterial isolates to fosfomycin has been determined by the agar dilution method. the mics of 364 strains have been determined by comparison of agar alone and agar plus glucose-6-phosphate. this later enhances the activity of fosfomycin. lastly, we studied frequency of mutation toward resistance for 109 susceptible strains. we obtained 88 stable mutants. | 1977 | 401717 |
| cefoxitin and cephamycins: microbiological studies. | the cephamycins are a family of beta-lactam antibiotics that are produced by actinomycetes and are structurally similar to the cephalosporins. they are characterized by the presence of a 7-alpha-methoxyl group, which confers unusually high resistance to beta-lactamases. cefoxitin, the first semisynthetic cephamycin, is resistant to almost all beta-lactamases. cefoxitin retains the 3-carbamoyl group of cephamycin c and thus has excellent metabolic stability. cefoxitin is bactericidal and almost d ... | 1979 | 400941 |
| infections due to endemic, multiply resistant gram-negative rods: sensitivity to and therapy with cefoxitin. | a nosocomial outbreak of infections due to bacteria resistant to multiple antibiotics evolved into an endemic prevalence of several antibiotic-resistant gram-negative rods. the resistance of these bacteria to available beta-lactam antibiotics, a variety of broad-spectrum agents, and available aminoglycosides other than amikacin led to an evaluation of cefoxitin, a beta-lactamase-resistant cephamycin. most multiply resistant isolates of klebsiella pneumoniae, serratia marcescens, and proteus mira ... | 1979 | 400932 |
| in vitro and in vivo studies with bl-s786, cefoxitin, and cefamandole. | the in vitro antimicrobial activities of bl-s786, cefoxitin, and cefamandole against 90 isolates of enterobacteriaceae, including escherichia coli, klebsiella pneumoniae, proteus mirabilis, enterobacter cloacae and e. aerogenes, were studied by using an agar dilution procedure. comparison of geometric mean minimal inhibitory concentrations showed that bl-s786 was half as active as cefamandole against enterobacter species, 2 to 4 times more active than cefamandole against all other species, and 4 ... | 1978 | 400821 |