| a survey of iga protease production among clinical isolates of proteeae. | a collection of 100 strains of proteeae, in which all species within the tribe were represented, was examined for iga protease production. the strains were isolated from various clinical specimens from sick and healthy persons in several countries. iga protease-producing strains were not found amongst species of providencia and morganella but were common in proteus spp. all the strains of p. mirabilis and p. penneri and many of the strains of p. vulgaris examined produced an edta-sensitive prote ... | 1988 | 3275781 |
| rapid antibiotic susceptibility tests on enterobacteriaceae by atp bioluminescence. | the susceptibility of 76 clinical isolates of enterobacteriaceae to ampicillin, piperacillin and gentamicin was assessed by atp bioluminescence in a 4-h test. for most organisms tested (escherichia, klebsiella, enterobacter and serratia), there was good correlation with traditional mic values estimated on 18-h cultures. however strains of proteus mirabilis showed false resistance to the beta-lactam agents with the atp method; and concordance was achieved only after manipulation of the growth con ... | 1988 | 3276899 |
| cloning of the recb, recc, and recd genes from proteus mirabilis in escherichia coli: in vivo formation of active hybrid enzymes. | we cloned chromosomal dna fragments from proteus mirabilis which complement recbcd deletion mutants of escherichia coli by restoring (i) recombination proficiency in conjugation, (ii) normal resistance to uv irradiation, and (iii) atp-dependent exonuclease activity for duplex dna. the data indicate that the order of the genes thya, recc, recb, recd, and arga is similar in both p. mirabilis and e. coli. hybrid enzymes formed in vivo were active in repair and recombination. | 1988 | 3277957 |
| commercial identification systems often fail to identify providencia stuartii. | we tested 145 clinical isolates in an attempt to evaluate some of the most widely used commercial identification systems in europe in terms of their ability to identify providencia strains. two manual miniaturized systems (api 20e and enterotube ii) and three mechanized-automated systems (cobas-bact, sceptor system, and titertek-enterobac-rapid automated system) were evaluated. providencia alcalifaciens and providencia rettgeri strains were correctly identified by all systems in all cases, and i ... | 1988 | 3277997 |
| tigemonam, an oral monobactam. | tigemonam is an orally administered monobactam. at less than or equal to 1 microgram/ml it inhibited the majority of strains of escherichia coli, klebsiella spp., enterobacter aerogenes, citrobacter diversus, proteus spp., providencia spp., aeromonas hydrophila, salmonella spp., shigella spp., serratia marcescens, and yersinia enterocolitica. at less than or equal to 0.25 microgram/ml it inhibited haemophilus spp., neisseria spp., and branhamella catarrhalis. it did not inhibit pseudomonas spp. ... | 1988 | 3279906 |
| structural studies on the core and lipid a region of a 4-amino-l-arabinose-lacking rc-type mutant of proteus mirabilis. | the structure of the 4-amino-l-arabinose-lacking lipopolysaccharide of the proteus mirabilis rc-type mutant r4, derived from wild-type o28, was elucidated. the lipopolysaccharide core structure has previously been partially characterized. the linkage between heptose and deoxyoctulosonic acid(docla) is now reported, as well as the structure of the lipid a moiety of this mutant strain. besides the tentative identification of an alpha-linked glucosamine disaccharide in the lipid a backbone accompan ... | 1988 | 3280311 |
| thrombocytosis and a renal abscess. | | 1988 | 3281051 |
| proteus syndrome: ocular complications. | proteus syndrome is a recently recognized hamartoneoplastic malformation syndrome of uncertain etiology and variable expression, whose cardinal manifestations are pigmented nevi, hemihypertrophy, macrodactly, lipomata, and cerebroid-gyriform configuration of the skin on the soles of the feet. the characteristic features may be present at birth but become more apparent with time. in the past this syndrome has been confused with other overgrowth disorders such as neurofibromatosis, klippel-trenaun ... | 1988 | 3282059 |
| comparison of translocation rates of various indigenous bacteria from the gastrointestinal tract to the mesenteric lymph node. | bacterial translocation is defined as the passage of indigenous bacteria from the gastrointestinal (gi) tract through the lamina propria to the mesenteric lymph nodes (mln) and other organs. we compared the relative abilities of various aerobic, facultatively anaerobic, and obligately anaerobic bacteria to translocate from the gi tract to the mln in gnotobiotic mice colonized with single strains of bacteria. indigenous gram-negative enteric bacilli translocated in large numbers to the mln, where ... | 1988 | 3283254 |
| [bacterial spondylitis]. | | 1988 | 3283510 |
| [experimental comparison of maxon and chromic catgut in suturing of the urinary bladder]. | the new monofile absorbable suture material maxon was compared with chromic catgut in bladder suturing in rabbits. comparisons were made after 1, 2, 4, 8 and 12 weeks. the rate of stone formation was mainly determined by the suture technique used and not so much by the suture material. this was demonstrated by the low number of stones formed after using extramucosal suturing technique. once a suture, be it maxon or chromic catgut, comes in contact with urine, concrements may form and the new mon ... | 1988 | 3284147 |
| a positive response to any of seven intradermal antigens predicts favorable outcome in patients hospitalized with community-acquired pneumonia. | we used the commercially available multitest (r) cmi to assess the response of 100 adults hospitalized with community-acquired pneumonia to the following seven antigens: tetanus toxoid, diphtheria toxoid, streptococcus, proteus, tuberculin, candida, and trichophyton. thirty-one of the patients responded to one or more of these antigens and survived their acute illness. of the multitest (r) cmi negative patients, 49 lived and 20 died. a comparison of the three groups revealed that the 31 patients ... | 1988 | 3284671 |
| is pelvic inflammatory disease an indication for treatment with ciprofloxacin? | this pilot study was carried out on 23 gynaecological patients suffering from salpingitis, salpingitis and pelviperitonitis, douglas' abscess, and vaginal stump abscess. 21 courses were evaluable for clinical efficacy. the diagnoses had been established mainly by pelviscopy and by clinical gynaecological examinations. the dosage was 2 x 500 mg ciprofloxacin orally every 12 h for 7.6 (5-11) days. cervical smears collected before therapy revealed the most common pathogens to be escherichia coli an ... | 1988 | 3286515 |
| conservation of an atp-binding domain among reca proteins from proteus vulgaris, erwinia carotovora, shigella flexneri, and escherichia coli k-12 and b/r. | the purified reca proteins encoded by the cloned genes from proteus vulgaris, erwinia carotovora, shigella flexneri, and escherichia coli b/r were compared with the reca protein from e. coli k-12. each of the proteins hydrolyzed atp in the presence of single-stranded dna, and each was covalently modified with the photoaffinity atp analog 8-azidoadenosine 5'-triphosphate (8n3atp). two-dimensional tryptic maps of the four heterologous reca proteins demonstrated considerable structural conservation ... | 1988 | 3286605 |
| nature of monocyclic beta-lactam antibiotic nocardicin a to beta-lactamases. | nocardicin a is the antibiotic which was first found to possess a monocyclic beta-lactam ring. this antibiotic was inactivated by the cleavage of its beta-lactam ring. the direct spectrophotometric assay was applied to measure the rate of enzymatic hydrolysis of nocardicin a. nocardicin a was highly stable to both chromosomal and plasmid-mediated beta-lactamases. of the nine beta-lactam antibiotics including cefoxitin and cefuroxime, nocardicin a was the most stable to the beta-lactamases tested ... | 1988 | 3287105 |
| a multicenter comparative study of cefotetan once daily and cefoxitin thrice daily for the treatment of infections of the skin and superficial soft tissue. | to compare the effectiveness of cefotetan administered at 2 g once a day with cefoxitin at 1 or 2 g three times a day in the treatment of hospitalized patients with skin and superficial soft tissue infections, 194 patients from eight centers were enrolled in an open, randomized trial. most of the 104 evaluable patients in the cefotetan group and 50 in the cefoxitin group were young men with community-acquired, moderate or severe cellulitis, or abscesses of the upper and lower extremities caused ... | 1988 | 3287976 |
| carumonam's in-vitro activity against gram-negative bacteria and its stability to their beta-lactamases. | the in vitro activity of the novel monobactam carumonam (ro17-2301) was evaluated on 311 gram-negative clinical isolates in comparison to aztreonam, cefotaxime, ceftazidime, cefotetan and ceftriaxone. carumonam showed an antibacterial potency equal to or higher than any other reference compound; in particular it was the most effective against proteus indole positive and klebsiella sp. its antipseudomonal activity was comparable to that of ceftazidime and it showed, together with aztreonam, the h ... | 1988 | 3288365 |
| intravesical migration of lippes loop with stone formation. | a case is described of a 47-year old multipara, presenting with dysuria and frequency. urinalysis showed pus and proteus mirabilis infection, and radiography revealed the presence in the bladder of 2 stones joined together by a migrated and entrapped lippes loop, which had been inserted 14 years previously, after the birth of her 5th child. | 1988 | 3289679 |
| circumcision and periurethral carriage of proteus mirabilis in boys. | swabs were taken for culture from the periurethral area and urethral meatus in 124 uncircumcised and 60 circumcised boys. proteus mirabilis was grown from 28 (22.6%) swabs from uncircumcised boys and from only one (1.7%) swab from circumcised boys. this supports the idea that the prepuce may be the source of proteus urinary tract infection. | 1988 | 3291784 |
| [dynamics of drug resistance in proteus mirabilis cultures 1970-1985]. | resistance of 669 clinical strains of proteus mirabilis to 18 chemotherapeutic drugs was studied in dynamics within 1970-1985. an increase in the number of cultures resistant to ampicillin and carbenicillin was noted while the number of cultures resistant to cephalosporines did not change. within the period from 1970 to 1975 there was observed a marked increase in the number of proteus strains resistant to aminoglycoside antibiotics. after that period their number gradually lowered and in 1985 r ... | 1988 | 3291802 |
| proteus mirabilis urease. partial purification and inhibition by boric acid and boronic acids. | urease was purified 800-fold and partially characterized from proteus mirabilis, the predominant microorganism associated with urinary stones. boric acid is a rapid reversible competitive inhibitor of urease. the ph-dependence of inhibition exhibited pka values of 6.25 and 9.3, where the latter value is probably due to the inherent pka of boric acid. three boronic acids also were shown to inhibit urease competitively. | 1988 | 3291857 |
| the production of anorexigenic substances by intestinal flora. | the role of intestinal flora in the production of anorexigenic substance was investigated. proteus mirabilis (p. mirabilis) and escherichia coli (e. coli) were found to produce an anorexigenic substance, while enterococcus faecalis (e. faecalis, type 1 and 2) and staphylococcus intermedius (s. intermedius) did not. the anorexigenic substance was purified and was detected as, a single though broad band by sodium dodecyl sulfate polyacrylamide gel electrophoresis (sds-page). the specific activity ... | 1988 | 3291869 |
| experience with antimicrobial combinations in urinary tract infections. | four antimicrobial combinations were tried in the management of recurrent upper urinary tract infections: (i) rifampicin + trimethoprim (50 patients); (ii) amoxycillin + clavulanic acid (50 patients); (iii) ampicillin + sulbactam (10 patients); and (iv) pivampicillin + pivmecillinam (50 patients). the initial and final microbiological success rate was excellent with all four drug combinations; all were well tolerated. although monotherapy should be the rule in antimicrobial chemotherapy, there a ... | 1988 | 3292180 |
| bacterial translocation in dianhydrodulcitol-treated mice. | escherichia, proteus, klebsiella and streptococcus strains were isolated from mesenteric lymph nodes, spleens and livers of conventional mice treated with dianhydrodulcitol (dad), indicating that intestinal bacteria had appeared in organs usually containing no bacteria. the frequency of bacterial translocation showed direct relation to the dose of the drug and appeared simultaneously with the spleen atrophy caused by dad. | 1988 | 3293340 |
| production of a phosphatidylglycerol-like substance by genital flora bacteria. | bacteria contaminating amniotic fluid have anecdotally been shown to produce a phosphatidylglycerol-like substance, thus giving false positive tests for phosphatidylglycerol in vaginal pool fluid from patients with premature rupture of the membranes. isolates of escherichia coli, proteus mirabilis, acinetobacter calcoaceticus, klebsiella pneumoniae, staphylococcus aureus, coagulase-negative staphylococcus, streptococcus faecalis, and streptococcus agalactiae (group b streptococcus) were grown in ... | 1988 | 3293449 |
| comparative in vitro activity of amoxycillin/clavulanate (augmentin), ceftazidime and ceftriaxone against hospital strains of gram-negative and -positive bacteria. | the in vitro antibacterial activities of amoxycillin/clavulanate (augmentin), ceftazidime and ceftriaxone were compared against 330 gram-negative and gram-positive strains isolated from clinical specimens received at the king abdulaziz university hospital (kauh) in saudi arabia. the antibacterial susceptibility was determinated by stokes method and by the minimal inhibitory concentration (mic) using an agar dilution method. ceftazidime and ceftriaxone were the most active antibiotics, inhibiting ... | 1988 | 3293818 |
| evaluation of the in vitro susceptibility of gram-negative bacilli to cefotaxime, over a period of 3 years. | | 1988 | 3293972 |
| bacteriuria following extracorporeal shock wave lithotripsy of infection stones. | extracorporeal shock wave lithotripsy effectively pulverizes infected (struvite) renal calculi. however, after treatment minute residual fragments that may harbor bacteria and cause persistent bacteriuria remain in the renal collecting system for months. we investigated prospectively the incidence of persistent proteus mirabilis bacteriuria after extracorporeal shock wave lithotripsy among 15 consecutive women with proteus mirabilis urinary tract infections and struvite calculi. all patients rec ... | 1988 | 3294439 |
| adherence of urease-induced crystals to rat bladder epithelium following acute infection with different uropathogenic microorganisms. | apart from urine supersaturation with respect to struvite and calcium phosphate, crystal retention is considered to be necessary for the formation of infection stones. this study was performed to investigate the role of the mucous coat in rat bladders in the adhesion of sterile urease-induced crystals and to determine to what extent the adhesion was influenced by infection. elimination of the mucous coat with 0.1 m hcl increased the adherence of crystals six times compared to that in bladders wi ... | 1988 | 3294448 |
| [etiology of corneal ulcers with special reference to bacterial genesis]. | the authors report on 134 patients (141 eyes) seen between may 1982 and december 1985 with corneal ulcers with or without hypopyon. eight patients (11 eyes) had a facial palsy, 7 (7 eyes) a varicella zoster infection, 1 (2 eyes) a marginal ulcer ("furrow keratitis") associated with collagenosis, 29 (29 eyes) an ulcerative keratitis with endophthalmitis, 1 (2 eyes) a pemphigoid-associated ulcer and 90 (92 eyes) a herpetic infection. pathogenic bacterial strains were isolated from 20 patients: 10 ... | 1987 | 3295371 |
| apalcillin treatment of complicated urinary tract infections. | in an open, prospective clinical trial, we evaluated the safety and efficacy of apalcillin in the treatment of complicated urinary tract infection. 21 hospitalized adult patients received apalcillin 2 g iv q8-12 h for 5-17 days. there were 8 upper tract and 13 lower tract infections. of 25 functional or anatomic abnormalities of the gu tract among these patients, 9 (36%) were corrected during the study period. effectiveness of apalcillin was determined by clinical and bacteriologic response. 16 ... | 1987 | 3296387 |
| [immunostimulant preparation made from the antigens of opportunistic microorganisms in the treatment of inflammatory lung diseases]. | the results of the trial of an immunostimulating preparation, consisting of klebsiella pneumoniae, proteus, escherichia coli and staphylococcus antigenic complexes, on 20 patients with acute pulmonary abscess and bronchiectasis are presented. the preparation was introduced subcutaneously in 5 injections. the preparation was found to have low reactogenicity, and in the course of immunotherapy the manifestations of systemic and local reactions became considerably less pronounced. immunotherapy pro ... | 1987 | 3296578 |
| [thrombophlebitis of the lateral sinus. apropos of a case]. | | 1987 | 3296844 |
| chronic urinary tract infection in dogs: induction by inoculation with bacteria via percutaneous nephropyelostomy. | dogs were inoculated via percutaneous nephropyelostomy with bacteria isolated from canine patients with urinary tract infections (4 dogs were inoculated with escherichia coli, 2 were inoculated with proteus mirabilis, and 1 was inoculated with coagulase-positive staphylococci). at approximately monthly intervals after bacterial inoculation, bladder urine specimens were collected via antepubic cystocentesis, and renal pelvic urine specimens were collected via percutaneous nephropyelocentesis. dog ... | 1987 | 3296890 |
| humoral response in mice immunized with outer membrane proteins of shigella flexneri. | intraperitoneal immunization of mice with outer membrane proteins (omp) of sh. flexneri induced in the animals a synthesis of specific antibodies. their level determined by elisa test was found to be relatively low in the sera of animals immunized with a single dose (10 micrograms) of omp; it was markedly higher in mice immunized with two doses of omp, and very high after three fold immunization. the specific antibodies maintained in the animals for 8-16 weeks after immunization. anti-omp sera g ... | 1986 | 3296993 |
| cell invasiveness of proteus mirabilis and proteus vulgaris strains. | cell penetration ability of haemolytic and non haemolytic proteus rods was compared. among four proteus strains all were able to invade the tested cells (vero 135, hela, l-929 and human blood lymphocytes) but the expression of this feature by haemolytic strains was markedly higher. the survival and multiplication of intracellular bacteria, especially in the case of fresh human blood lymphocytes may be of importance for the development of infection in higher organisms. | 1986 | 3296994 |
| [morphologic manifestations of intestinal lesions of bacterial and mycotic etiology developing in association with acute respiratory infections]. | by means of light and immunofluorescent microscopy the intestines of 34 children were studied, whose bacterial or mycotic enterocolitis most often combined with acute respiratory infections. intestinal lesions were caused either by virus (sometimes by mycoplasma), or by bacteria and fungi. such changes developed in the debilitated children and their course was more severe, than in monoinfections because of the impaired systemic and local immunity, and probably due to formation of viral-bacterial ... | 1987 | 3297004 |
| urease activity related to the growth and differentiation of swarmer cells of proteus mirabilis. | urease activity was measured using whole cells of both long (swarming) and short (nonswarming) populations of proteus mirabilis from casein hydrolysate agar (cha) and broth (chb) cultures, and from brain heart infusion broth (bhib) cultures. urease is a constitutive enzyme for both long and short cells, but its activity was tremendously increased when urea was incorporated into the media. urease production was also affected by culture age and media used. before exponential phase, urease activity ... | 1987 | 3297270 |
| magainins, a class of antimicrobial peptides from xenopus skin: isolation, characterization of two active forms, and partial cdna sequence of a precursor. | a family of peptides with broad-spectrum antimicrobial activity has been isolated from the skin of the african clawed frog xenopus laevis. it consists of two closely related peptides that are each 23 amino acids and differ by two substitutions. these peptides are water soluble, nonhemolytic at their effective antimicrobial concentrations, and potentially amphiphilic. at low concentrations they inhibit growth of numerous species of bacteria and fungi and induce osmotic lysis of protozoa. the sequ ... | 1987 | 3299384 |
| a highly sensitive bacterial assay for toxins based on swarming inhibition, and comparison with the cup plate assay based on growth inhibition. | the motility inhibition of the swarming bacteria proteus mirabilis and azospirillum brasilense was found to be an appropriate parameter to indicate toxic effects caused by some mycotoxins, lactones and anhydrides of dicarboxylic acids. if these substances are in contact with the motile bacteria the following phenomena can be observed: at a certain toxin concentration the swarming of the bacteria is inhibited. if the concentration is increased the swarming ceases, and at still higher concentratio ... | 1987 | 3299877 |
| [effect of polyvinylpyrrolidone on microbial cells]. | the oral administration of polyvinylpyrrolidone to rats produces no effect on the intestinal microflora. at the same time, polyvinylpyrrolidone solutions decrease the toxicity of escherichia coli and proteus vulgaris, produce a bactericidal and agglutinating effect. | 1987 | 3300111 |
| in vitro activity and beta-lactamase stability of a new monobactam, b0-1165. | b0-1165 is a 1-carboxy-1-cyclopropoxyamino,4-fluoromethyl monobactam. it inhibited the majority of escherichia coli, klebsiella pneumoniae, klebsiella oxytoca, citrobacter diversus, aeromonas hydrophila, proteus mirabilis, proteus vulgaris, providencia rettgeri, providencia stuartii, yersinia enterocolitica, haemophilus influenzae, neisseria gonorrhoeae, and salmonella and shigella species at less than or equal to 0.125 microgram/ml. overall, its in vitro activity was similar to that of aztreona ... | 1987 | 3300528 |
| outbreak of wound infections following outpatient podiatric surgery due to contaminated bone drills. | an outbreak of podiatric infections due to an uncommon strain of proteus mirabilis occurred following outpatient podiatric surgery. an evaluation of the operating room environment failed to reveal the strain of p. mirabilis from any site other than three bone drills. thus the drills served as the reservoir for the organism that was subsequently inoculated onto the hands of the surgeon or directly to a patient during bone drilling. the gas sterilization procedure that was used to sterilize the dr ... | 1987 | 3301597 |
| inhibition of growth and swarming of proteus mirabilis and proteus vulgaris by triclosan. | the mics of triclosan (2,4,4'-trichloro-2'-hydroxydiphenyl ether) and the effect on swarming were determined for 35 isolates of proteus mirabilis and 7 isolates of p. vulgaris of animal origin. both species were susceptible to the antimicrobial agent, and growth of all but one isolate was inhibited by less than 1 microgram/ml in broth and on agar without blood. swarming was inhibited at triclosan concentrations two- to fourfold less than the mics. higher concentrations were required with blood a ... | 1987 | 3301894 |
| [comparative, controlled study on an ampicillin suppository (ks-r 1) with an oral form of ampicillin in urinary tract infections]. | subjects were in-patients with bacterial urinary tract infections, ranging in age 4 months to 11 years 4 months. as a rule, daily dose was either four 125 mg (in potency) suppositories or four 125 mg (in potency) oral form given at 6-hour intervals over a period of 5 days. the number of children subjected to this study was 105. these children were divided into 2 groups (suppository 54; oral form 51) with matched pretreatment background factors. therapeutic effectiveness rates were 70.4% for the ... | 1987 | 3302342 |
| scanning electron microscopic examinations of renal stones associated with urinary infections. | | 1987 | 3302428 |
| biological activities of chemically synthesized proteus-type lipid a. | | 1987 | 3302626 |
| [treatment of febrile episodes in neutropenic children by ceftazidime combined with netilmicin. results of a multicenter study apropos of 88 cases]. | infection is the most important cause of mortality in leucopenic patients. a broad spectrum antibiotic therapy is imperative in febrile and neutropenic patients. in a multicentric study we have used ceftazidime (100 mg/kg/d) and netilmicin (6 mg/kg/d) in 88 children (fever greater than or equal to 38.5 degrees c, neutropenia less than 500/mm3) treated for acute leukemias (59), non hodgkin lymphomas (13) or solid tumors (16). median age was 7 years (2 months-16 years). in patients who continued t ... | 1987 | 3302878 |
| biofilms on right heart flow-directed catheters. | this study was designed to detect biofilm and bacteria on right heart flow-directed catheters using scanning electron microscopy and culture following scraping and dispersion of biofilm by sonication. we examined 20 consecutive catheters removed from 18 critically ill patients, an average of 2.6 days after insertion. on scanning electron microscopy, all catheters were found to be covered by a biofilm, with bacteria visible on 50 percent of them. cultures of specimens from 40 percent of the cathe ... | 1987 | 3304847 |
| identification of two different hemolysin determinants in uropathogenic proteus isolates. | dna sequences similar to those of the escherichia coli hemolysin genes were detected among uropathogenic isolates of proteus vulgaris and morganella morganii by using the southern blotting technique and hly gene-specific dna probe. immunoblotting revealed that among the hemolytic p. vulgaris and m. morganii isolates there was expressed a polypeptide species similar in molecular size (110 kilodaltons) and antigenicity to escherichia coli hlya. a plasmid-mediated p. vulgaris hemolysin determinant ... | 1987 | 3305367 |
| the penicillins. | the penicillin family of antibiotics is ever expanding and remains an important part of our antimicrobial armamentarium. these medications generally have bactericidal activity, excellent distribution throughout the body, low toxicity, and efficacy against infections due to susceptible organisms. the clinical introduction of aqueous penicillin g for treatment of streptococcal and staphylococcal infections was an important pharmacologic landmark. the emergence of penicillinase-producing staphyloco ... | 1987 | 3306181 |
| cephalosporin, carbapenem, and monobactam antibiotics. | cephalosporin and related antibiotics are highly effective bactericidal agents of relatively low toxicity. the spectrum of activity varies with the drug but is usually broad. the first-generation cephalosporins, and especially cefazolin, are most active against sensitive staphylococci and streptococci. most second-generation (except cefoxitin) and third-generation cephalosporins show substantial activity against haemophilus influenzae. all cephalosporins (except cefsulodin) are active against kl ... | 1987 | 3306182 |
| [resistance of urinary flora from sources outside the hospital]. | | 1987 | 3306193 |
| functional neutrophils from long-term murine bone marrow cell cultures. | murine bone marrow cell cultures that had been established for up to 26 weeks were harvested each week and found to provide functional neutrophils. leukocytes harvested from the cultures were enriched for neutrophils using discontinuous percoll density gradients. these cells mounted a chemiluminescence response to proteus mirabilis in the presence of normal mouse serum (nms). they killed several nms-opsonised bacterial species, an activity that was blocked by a monoclonal antibody to the c3 rece ... | 1987 | 3298437 |
| [metabolism of c14-labelled urea in conventional, germ-free and specifically associated rats]. | | 1987 | 3303739 |
| paradoxical antibacterial activity of cefmenoxime against proteus vulgaris. | the growth-inhibitory effect of cefmenoxime against proteus vulgaris was studied by using the broth dilution and paper disk diffusion methods. cefmenoxime showed growth-inhibitory activity against proteus vulgaris at low concentrations but not at high concentrations up to a certain limit. this paradoxical antibacterial activity was not observed with cefoperazone and cefbuperazone. the induction of beta-lactamase by cefmenoxime and the rate of hydrolysis of cefmenoxime in the culture broth were p ... | 1987 | 3304155 |
| [acetohydroxamic acid in the treatment of kidney calculi caused by an infection with urease-producing microorganisms]. | | 1987 | 3306625 |
| [transference and resistance to serum in gram-negative strains multiresistant to antimicrobial drugs]. | | 1987 | 3306858 |
| gentamicin resistance among gram-negative bacillary blood isolates in a hospital with long-term use of gentamicin. | between 1977 and 1985, gentamicin was the only formulary aminoglycoside at the buffalo veterans administration medical center. during this time, there was a significant increase in the amount of gentamicin purchased. amikacin represented 11% or less of the total aminoglycoside purchased in the same period, but purchases of this agent also significantly increased. because of this long-term use of gentamicin, a retrospective analysis of gentamicin resistance among gram-negative bacillary blood iso ... | 1987 | 3307673 |
| nucleotide sequence and comparative analysis of the frd operon encoding the fumarate reductase of proteus vulgaris. extensive sequence divergence of the membrane anchors and absence of an frd-linked ampc cephalosporinase gene. | the fumarate reductase of escherichia coli is a bioenergetically important membrane-bound flavoenzyme consisting of four subunits. a and b comprise a membrane-extrinsic catalytic domain whereas c and d are hydrophobic polypeptides which link the catalytic centres to the electron-transport chain. the nucleotide sequence of the frd operon encoding the fumarate reductase of the distantly related bacterium, proteus vulgaris has been determined and used to predict the primary structures of the respec ... | 1987 | 3308458 |
| proteus mirabilis pneumonia with giant pneumatocele. | | 1987 | 3308698 |
| comparative analysis of two rapid automated methods and a semiautomated version of the urease method for determining aminoglycoside concentrations in serum. | the syva emit autolab 6000 and the abbott tdx automated methods for measuring serum aminoglycoside concentrations were compared with each other and with a new semiautomated version of the urease technique. each was evaluated for accuracy, reproducibility, cost, and ease of use. all three methods gave satisfactory results, although the abbott tdx was the most accurate. both automated methods gave results within minutes, whereas the new urease method, which involved more initial manipulation, took ... | 1987 | 3308945 |
| effect of r-plasmid rp1 on surface hydrophobicity of proteus mirabilis. | the presence of r-plasmid rp1, as well as the conditions of growth, affected the surface hydrophobicity of a clinical isolate of proteus mirabilis. however, results depended upon the method of assessment. stationary phase plasmid-containing cells appeared to be less hydrophobic than plasmid-free cells when hydrophobicity was measured by the contact angle method, but more hydrophobic when measured by bacterial adherence to hydrocarbons or hydrophobic interaction chromatography. cells growing in a ... | 1986 | 3309134 |
| proteus mirabilis strains of diverse type have iga protease activity. | a strain of proteus mirabilis associated with chronic urinary tract infection was found to produce an edta-sensitive iga protease that cleaved the iga heavy chain into two fragments at sites different from those attacked by other microbial iga1 proteases. another 14 p. mirabilis strains of diverse type and from various clinical conditions also produced a similar iga protease. this enzyme may be a virulence determinant of p. mirabilis. | 1987 | 3309325 |
| [fosfomycin-trometamol (monuril): pharmacokinetics and food-drug interactions]. | a new water soluble monobasic salt of fosfomycin with trometamol has been recently developed for oral administration. the objective of this study was to evaluate the pharmacokinetics of trometamol-fosfomycin (monuril) in serum and urine in 10 healthy volunteers after oral administration of one single dose (50 mg/kg). in the volunteers, the concentrations of fosfomycin were measured before and after food absorption in serum and urine samples taken at t = 0, 2, 4, 6, 8, 24 h after the dose (plus 0 ... | 1987 | 3309810 |
| [epidemiology, clinical aspects and treatment of nosocomial septicemias]. | one hundred one nosocomial septicemias (ns) were studied among 461 cases of septicemias (22%) collected by french septicemia expert system group during 1985. the mean-age of the patients was 58 +/- 23 years while it was 56 +/- 23 years in the 360 community acquired septicemias (cas). the source of septicemia was found more frequently in ns than in cas (79/101 versus 223/360; p less than 0.002): mainly urinary tract and intravenous therapy in ns, urinary tract, gastrointestinal and biliary origin ... | 1987 | 3309823 |
| [septicemia of urinary origin. epidemiology and initial antibiotic treatment]. | the ses group was formed by the "ligue française pour la prévention des maladies infectieuses" to create a diagnostic and therapeutic expert system on septicemia. 461 cases of septicemia were thus collected from january 1 to december 31, 1985. 83 out of these septicemias had an urinary tract portal of entry, 21 were contracted in hospital. the mean age was 65 +/- 21 years (57 +/- 20 years for the 461 cases ns). there were 46 women and 37 men, i.e., a sex-ratio apposite to that of the overall pop ... | 1987 | 3309824 |
| in vitro and in vivo antibacterial activities of cs-807, a new oral cephalosporin. | cs-807 is a new oral prodrug of r-3746, a cephalosporin derivative, with potent in vitro and in vivo antibacterial activity against both gram-positive and gram-negative bacteria. the susceptibility of about 1,200 clinical isolates to r-3746 was determined by the agar dilution method. ninety percent or more of pathogens such as staphylococcus aureus, streptococci, escherichia coli, klebsiella pneumoniae, klebsiella oxytoca, indole-positive and indole-negative proteus spp., providencia rettgeri, a ... | 1987 | 3310868 |
| the action of sodium deoxycholate on escherichia coli. | sodium deoxycholate is used in a number of bacteriological media for the isolation and classification of gram-negative bacteria from food and the environment. initial experiments to study the effect of deoxycholate on the growth parameters of escherichia coli showed an increase in the lag time constant and generation time and a decrease in the growth rate constant and total cell yield of this microorganism. cell fractionation studies indicated that sodium deoxycholate at levels used in bacteriol ... | 1987 | 3310888 |
| clinical significance of beta-lactamase induction and stable derepression in gram-negative rods. | most strains of enterobacteria and pseudomonas aeruginosa produce chromosomally-determined class i beta-lactamases. when synthesized copiously these enzymes cause resistance to almost all beta-lactams, except imipenem and, sometimes, carbenicillin and tenocillin. elevated beta-lactamase production arises transiently, via induction, in pseudomonas aeruginosa and enterobacter, citrobacter, morganella, indole-positive proteus and serratia spp. when these organisms are exposed to beta-lactams. perma ... | 1987 | 3311738 |
| [comparative in vitro study of the antimicrobial activity of ceftazidime against clinical isolates]. | the antimicrobial activity of ceftazidime was tested against 1482 gram-negative and 1216 gram-positive strains isolated from fresh clinical specimens and compared with generally used antibiotics including other third generation cephalosporins and broad spectrum penicillins. minimal inhibitory concentrations were determined in a broth dilution test on microtiter plates. in the group of the gram-negative bacteria ceftazidime was the most active of the antimicrobial agents tested with an mic of 0.5 ... | 1987 | 3312026 |
| [ceftazidime versus cefotaxime in the therapy of severe infections in intensive care patients]. | in a randomized controlled, clinical study the efficacy of ceftazidime at a dosage of 2 g b. i. d. was compared to that of cefotaxime at a dosage of 2 g t. i. d. or more in the treatment of pneumonia or peritonitis in intensive care patients. 61 of 67 assessable cases were evaluable. in the ceftazidime group ten out of 11 patients with pneumonia and 17 out of 20 with peritonitis showed a clinical success. in the cefotaxime group 15 out of 19 patients with pneumonia and eight out of 11 with perit ... | 1987 | 3312030 |
| antibiotic treatment of chronic central venous hemodialysis catheter infection without catheter removal. | most catheter or shunt infections in hemodialysis patients require the removal of the access before the infection is eradicated. a hemodialysis patient is reported who had multiple previous vascular accesses which failed and thus who had very limited sites for future access placement. when a recurrent proteus mirabilis catheter infection occurred, a 6-week course of ampicillin intraluminal and tobramycin systematically, eradicated the infection and thus the central venous catheter was salvaged. ... | 1987 | 3312041 |
| infected false aneurysm following carotid endarterectomy with vein patch angioplasty. | the authors report a case of infected false aneurysm that developed after carotid endarterectomy with vein patch angioplasty. this complication is extremely rare and occurs most commonly when a dacron patch graft has been employed. various clinical presentations are described and the etiology of infection is discussed. surgical management consisted of the resection of the pseudoaneurysm and segmental replacement with vein. parenteral antibiotic therapy was given for three weeks and topical irrig ... | 1987 | 3312228 |
| r-plasmid rp1 promotes adhesion of gram-negative bacteria to medical prostheses and glass. | the presence of r-plasmid rp1 increased the adhesion of chemostat-grown iron- and carbon-limited proteus mirabilis to the surfaces of various medical prostheses and to glass. similar results were obtained with iron-limited pseudomonas aeruginosa and anaerobically-grown escherichia coli. changes in the surface properties of p. mirabilis indicated that the r-plasmid-mediated increase in negative charge was one of the factors that promoted adhesion. | 1987 | 3312609 |
| r-plasmid rp1 increases sensitivity of proteus mirabilis to normal body defences. | the bactericidal action of non-immune whole blood on proteus mirabilis was increased when the bacteria contained the r-plasmid rp1. this effect was due mainly to increased phagocytosis. iron-depleted stationary-phase cells were more sensitive than carbon-depleted cells. the contribution of serum was usually negligible but was increased during a minor non-specific infection. most plasmid-containing phenotypes were more sensitive than were those without plasmids but there were considerable differe ... | 1987 | 3312610 |
| endotoxin provocation of experimental renal cystic disease. | germ free rats provide a unique model in which to assess biological response to environment. in 48 germ-free male, sprague-dawley rats we examined the consequences of oral exposure to nordihydroguaiaretic acid (ndga), a nephrotoxin; to staphylococcus epidermidis and bacillus species, non-endotoxin-containing bacteria; to escherichia coli and proteus mirabilis, endotoxin-containing bacteria; and injected e. coli endotoxin on peripheral leukocyte counts and renal morphology. morphological changes ... | 1987 | 3312760 |
| [proteus syndrome: contribution to its clinical delineation]. | | 1986 | 3313555 |
| erythromycin-induced suppression of pulmonary antibacterial defenses. a potential mechanism of superinfection in the lung. | erythromycin is a broad-spectrum antibiotic commonly used in patients with respiratory infections. certain of these patients become colonized with new microorganisms and develop superinfections. antibiotics have a number of effects other than simply killing or inhibiting the growth of bacteria and may have direct effects upon host cells, including phagocytes. in vitro and in vivo studies have demonstrated that erythromycin decreases polymorphonuclear leukocyte (pmn) directed migration. to test t ... | 1987 | 3314615 |
| cefotaxime stability during in vitro microbiological testing. | cefotaxime is a broad-spectrum cephalosporin which is metabolized or degraded to less active or inactive metabolites by serum esterases, elevated temperatures, or a ph outside of its stability range. cefotaxime instability during in vitro microbiological susceptibility tests may lead to an underestimation of the antibacterial activity of the compound. cefotaxime and desacetylcefotaxime solutions were studied under mic and serum inhibitory titer testing conditions. cefotaxime concentrations, as m ... | 1987 | 3314698 |
| phosphomycin levels in serum and interstitial tissue fluid in a multiple dosage regimen in rabbits. | the evolution of phosphomycin (fosfocina), levels in serum and experimentally induced interstitial tissue fluid and the access of the drug to different organs were studied in rabbits after the administration of a single dose of 60 mg/kg and during a multiple dosage regimen of 60 mg/kg/6 h over three days. following the administration of a single dose a cmax value of phosphomycin in interstitial tissue fluid of 80.4 micrograms/ml was reached at 1.2 h. the elimination half-life of the drug from th ... | 1987 | 3314883 |
| ceforanide. a review of its antibacterial activity, pharmacokinetic properties and clinical efficacy. | ceforanide is a 'second generation' cephalosporin administered intravenously or intramuscularly. it is similar to cefamandole and cefonicid in its in vitro superiority to 'first generation' cephalosporins against several species of enterobacteriaceae as well as its activity against haemophilus influenzae, including beta-lactamase-producing strains. its activity against staphylococcus aureus is less than that of cefamandole, cefuroxime and first generation cephalosporins. the in vitro activity ag ... | 1987 | 3315624 |
| [retroperitoneal abscess: report of 2 cases]. | | 1987 | 3316484 |
| dimethyl sulphoxide respiration in proteus mirabilis. | dimethyl sulphoxide (dmso) was found to serve as an electron acceptor for the anaerobic growth of proteus mirabilis on fermentable substrates such as glucose and pyruvate, as well as on oxidizable substrates such as glycerol and lactate. in a complex medium, formate greatly stimulated growth in the presence of dmso. cell extracts were found to reduce dmso to dimethyl sulphide (dms) in the presence of an electron donor. it was found that nadh, formate, lactate, reduced benzyl viologen, and dithio ... | 1987 | 3316940 |
| [neonatal proteus infections]. | | 1987 | 3318632 |
| epidemiology of aerobactin production in enterobacteriaceae. | clinical isolates (496) of 10 different enterobacterial genera were studied for aerobactin excretion, colicin production and antibiotic resistance. in the case of escherichia coli, the incidence of aerobactin-positive strains in 108 blood isolates (45%) was not significantly different from that corresponding to faecal sources (41%). although colicin v production was much more frequently associated with aerobactin production than other colicins, colicin v was only produced by 26% of aerobactin ex ... | 1986 | 3318871 |
| computerized in vivo research from the growth of urease-producing bacteria in the presence of antibiotics combined with propionhydroxamic acid. | | 1987 | 3319403 |
| cephalosporins in the treatment of meningitis. | the synthesis of new cephalosporin antibiotics has provided agents which can effectively be used to treat most of the different forms of meningitis. none of the first generation cephalosporins can be considered acceptable as agents to treat meningitis. cefuroxime can be used to treat meningitis due to streptococcus pneumoniae, haemophilus influenzae and neisseria meningitidis in children. agents such as cefotaxime and ceftriaxone are appropriate for neonatal meningitis due to escherichia coli an ... | 1987 | 3319497 |
| urease-positive bacteriuria and obstruction of long-term urinary catheters. | long-term urethral catheterization (greater than or equal to 30 days), a management technique for urinary incontinence, results in polymicrobial bacteriuria. we frequently found urease-producing bacteria: of 1,135 weekly urine specimens from 32 long-term-catheterized patients, 86% had urease-positive bacterial species at greater than or equal to 10(5) cfu/ml. the most common species were proteus mirabilis and morganella morganii, each found in over half the specimens. p. mirabilis, but not other ... | 1987 | 3320089 |
| [combination of empyema of the gallbladder and typhoid]. | | 1987 | 3320468 |
| cloning and dna sequence determination of the l11 ribosomal protein operon of serratia marcescens and proteus vulgaris: translational feedback regulation of the escherichia coli l11 operon by heterologous l1 proteins. | in escherichia coli the genes encoding ribosomal proteins l11 (rplk) and l1 (rpla) are contained in a single operon and their expression is translationally regulated by l1. we have cloned the homologous genes from two other enterobacteria, serratia marcescens and proteus vulgaris, and determined nucleotide sequences. the genes are organized in a similar way to that found in e. coli. conservation of nucleotide and amino acid sequences relative to e. coli in the protein coding regions are 89.2% an ... | 1987 | 3323840 |
| [drug resistance of proteus vulgaris, proteus morganii and providencia rettgeri isolated from diagnostic specimens]. | | 1987 | 3324173 |
| [prospective studies on 73 cases of boutonneuse fever. validity of the clinico-epidemiological diagnosis and serology with respect to proteus]. | | 1987 | 3324224 |
| infection-induced urinary calculi and renal failure. | during 1974-1984 altogether 481 patients were treated for end-stage renal disease (esrd). eight patients, five women and three men, with chronic pyelonephritis as the primary cause of esrd, had staghorn urinary calculi as a predisposing factor for renal failure. these eight patients were studied retrospectively concerning epidemiological and bacteriological aspects, the treatment of the stone disease, and the development of uraemia. anatomical and metabolic abnormalities such as bladder outlet d ... | 1987 | 3324303 |
| [value of antibacterial therapy in chronic obstructive urinary tract infections]. | on the basis of a clinical study an analysis about 86 patients with obstructing bilateral nephrolithiasis and chronic obstructive infection of the urinary tract is elaborated. in order to illustrate the change of resistance of the causative agents during a period of 10 years (1973-1982) two separated 5-year analyses are compared. it is made evident that the relations of sensitivity to seven chemotherapeutic drugs in coli, proteus and pseudomonas infections have changed in favour of increasing re ... | 1987 | 3324549 |
| comparative activities of five antimicrobial agents in experimental proteus pyelonephritis in mice. | five antimicrobial agents, ciprofloxacin, ticarcillin, piperacillin, aztreonam and gentamicin, were compared both in vitro (mic's, time-kill studies) and in vivo, in the treatment of experimental proteus mirabilis pyelonephritis in mice. in the treatment of the pyelonephritis, ciprofloxacin was clearly superior to the other agents, both with respect to the percentage of sterile kidneys after treatment as with respect to the mean numbers of bacteria per kidney. the results can only be partially e ... | 1987 | 3325927 |
| ascending urinary tract infections in rats induced by staphylococcus saprophyticus and proteus mirabilis. | ascending pyelonephritis was induced by staphylococcus saprophyticus and proteus mirabilis both by inoculating the organisms separately and in combination into rat bladders. bacterial cultures of tissue homogenates showed that pyelonephritis by both bacteria occurred significantly more often in rats where the two organisms were instilled concomitantly, suggesting a synergistic virulence between the two species. the antibody response to the different organisms was the same either the bacteria wer ... | 1987 | 3326399 |
| [sensitivity to beta-lactam and aminoglycoside antibiotics of clinical proteus strains as dependent upon on their species classification and the source of their isolation]. | sensitivity of 130 proteus clinical strains was studied. among beta-lactam antibiotics cefotaxime showed marked advantages with respect to various proteus species. all the isolates of proteus mirabilis were sensitive to cefuroxime. cefamezin and cephapirin were inferior by their activity to cefotaxime and cefuroxime. they were characterized by close antibacterial activity and almost complete cross resistance. ampicillin and carbenicillin proved to be the least efficient among the tested beta-lac ... | 1987 | 3326520 |
| structure of the 0-specific polysaccharide of proteus mirabilis s 1959. | the complete structure of the 0-specific polysaccharide of the strain proteus mirabilis s 1959, as analyzed by 13c nmr, is presented. some data demonstrating the significant heterogeneity of the 0-specific chain in the investigated lipopolysaccharide are also described. | 1987 | 3326544 |
| [the antimicrobial activity of sisomicin against fresh clinical isolates]. | antimicrobial activities of sisomicin (siso) against clinical isolates obtained in the second half of 1986 were investigated together with other 4 aminoglycosides (ags) (gentamicin (gm), tobramycin (tob), dibekacin (dkb), amikacin (amk] and 2 cephems (cefotiam, cefotaxime), and were compared to the results reported in the period of late 1970's through early 1980's in japan. 1. the incidence of siso-resistant staphylococcus aureus in the present study was 18% and is comparable to that of the othe ... | 1987 | 3327965 |