Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| [antimicrobial effectiveness of sisomicin. i: in vitro activity of sisomicin compared with gentamicin, tobramycin, amikacin and kanamycin (author's transl)]. | the aminoglycosides sisomicin, gentamicin, tobramycin, amikacin and kanamycin are highly active against staphylococci including the penicillinase-positive strains. sisomicin is more effective than amikacin and kanamycin. mixed infections with staphylococci and enterobacteriaceae or pseudomonas aeruginosa are thus on indication for treatment with sisomicin or other aminoglycosides. infections with e. coli, enterobacter, susceptible klebsiella, and susceptible pseudomonas strains can be treated wi ... | 1976 | 789246 |
| [bacteriological studies in outpatients with acute urinary tract infections with particular reference to the resistance spectrum (author's transl)]. | bacteriological investigation of urinary samples from 1,926 non-hospitalised patients with documented or suspected acute urinary tract infection revealed organisms pathogenic for the urinary tract in 56.4% of the patients, who came from various parts of west germany. prevalent pathogens were e. coli (69%) and proteus mirabilis (14%). e. coli and p. mirabilis demonstrated a low rate of resistance against ampicillin, the cephalosporines, gentamicin, tobramycin, and also against nitrofurantoin, nal ... | 1976 | 789245 |
| long-term study of humoral immune response in patients with chronic pyelonephritis. | indirect immunofluorescence was used for the measurement of serum antibody titers against the hemologous urinary strain of infecting organism in patients with a clinical diagnosis of chronic pyelonephritis. the passive hemagglutination technique was employed for comparison. the antibody response of the patients was followed-up for a period of two to four years. in contrast to titers determined by hemagglutination, antibody titers determined by immunofluorescence were found to be persistently ele ... | 1976 | 788977 |
| [clinical study on the assessment of bladder puncture in the diagnosis of urinary tract infections]. | 1976 | 788367 | |
| [the anodically moving thermolabile antigen (ata) of gram-negative bacteria: its molecular heterogeneity and its chemical composition]. | the anodically-moving thermolabile antigen (ata) of gram-negative bacteria represents a glycolipoprote in. in aqueous solution ata exhibits heterogeneity of the molecular size, the range varying between 2.10(4) and 8.10(5) daltons. in the molecular range between 5.10(4) and 8.10(5) all the molecular states give precipitation lines with the corresponding antisera. it could be shown that all the molecular states of ata are formed by different aggregation of the same subunit with a molecular weight ... | 1976 | 788362 |
| the anodically-moving thermolabile antigen (ata) of gram-negative bacteria: its function as the receptor for f pili. | 1976 | 788356 | |
| [post-partum infectious sacro-iliitis caused by "commonplace bacteria" (proteus mirabilis?)]. | 1975 | 788081 | |
| sensitivity patterns of urinary pathogens in the southland community and a study of sewage flora. | the overall sensitivity pattern of the three main urinary pathogens to the commonly used oral antibodies exceeded 80 percent. the incidence of multiple resistant escherichia coli was 8 percent. the resistant patterns of the sewage e. coli resembled that of the resistant urinary e. coli. however only one-third of the resistant urinary e. coli showed multiple resistance whereas two-thirds of the resistant e. coli in the sewage showed this feature. the resistance transfer was low in organisms isola ... | 1976 | 787846 |
| properties of plasmids constructed by the in vitro insertion of dna from rhizobium leguminosarum or proteus mirabilis into rp4. | plasmids have been constructed by insertion of dna from rhizobium leguminosarum or proteus mirabilis into rp4 (an r factor of group p). such recombinant plasmids retain the wide host range of the parental plasmid, being as efficiently transmissible as the unmodified rp4 and are stably maintained in rapidly growing cultures. the recombinant plasmids, even though each contained a dna sequence absolutely identical with that of the host strain, are no more efficient at mobilizing the transfer of chr ... | 1976 | 787766 |
| transcription of escherichia coli ribosomal dna in proteus mirabilis. | transcription of escherichia coli ribosomal dna introduced into proteus mirabilis on f14 is described. we have developed an assay for e. coli coded ribosomal rna involving fingerprinting of ribonuclease t1 digests of rna isolated from ribosomal subunits. sequence differences in the ribosomal rna of the two species have allowed us to detect e. coli coded 16s, 23s, and 5s ribosomal rna in ribosomal subunits of the e. coli-p. mirabilis hybrid. the proportion of e. coli coded rrna in the hybrid is f ... | 1976 | 787756 |
| formation of crystalline deposits by several genera of the family enterobacteriaceae. | several species of bacteria from the family enterobacteriaceae formed crystalline materials containing calcium when grown in a defined culture medium. enterobacter aerogenes, proteus vulgaris, citrobacter freundii, and c. intermedius produced calcium pyrophosphate crystals. edwardsiella tarda and escherichia coli formed calcite iii crystals, whereas proteus mirabilis, klebsiella pneumoniae, providencia stuartii, and serratia marcescens produced hydroxyapatite crystals. several of these bacteria ... | 1976 | 786887 |
| [amikacin in urinary tract infections with so-called problem pathogens]. | amikacin (biklin) was applied in 33 patients with and without renal insufficiency, suffering of non-obstructive inflammations of the urinary tract, caused by multiple resistant hospital germs. the dosage was 125.0--1000.0 mg/die, injected as short infusion and solved in dextrose 5%. the serum and urine concentrations were measured simultaneously. in 18 cases an infection could not be seen after a control period of 8 days up to 4 weeks. persistence of bacteria happened in five cases. reinfection ... | 1976 | 786834 |
| phospholipid and lipopolysaccharide in proteus mirabilis and its stable protoplast l-form. difference in content and fatty acid composition. | cells of the stable protoplast l-form of proteus mirabilis contain 1.5 to 2 times more extractable lipid, mostly phospholipid, per dry weight than cells of the bacterial form. under identical conditions of cultivation the qualitative and quantitiative composition of the phospholipid is very similar in both cell forms. the range of mole percentages of individual phospholipid species is 78-80 for phosphatidylethanolamine, 10-13 for phosphatidylglycerol, 3.9-5.5 for diphosphatidylglycerol and 1.0-2 ... | 1976 | 786631 |
| studies of neonatal calf diarrhorea, v. water balances in calves with mixed infections. | 1976 | 786441 | |
| [plasmid determined lactose positive character in (enterobacter hafniae) and (proteus morganii) (author's transl)]. | the atypical lactose positive characters have been found to be plasmidmediated in 6 strains of enterobacter hafniae and 2 strains of proteus morganii. one of the p. morganii plasmid possesses the fi+ character, all the other plasmids belonging to the fi-group. both plasmids of p. morganii could be transduced and remained then readily transferably by conjugation. two of the e. hafniae plasmids were found unstable when harboured in salmonella typhi grown at 40 degrees centigrade, when they were st ... | 1976 | 786102 |
| a rapid and sensitive determination of bacterial rrna by means of hybridization-competition. | 1976 | 786069 | |
| [results in the treatment of anal fistula]. | 1976 | 785872 | |
| [current hospitalismus. contribution to the causal factors of problem infection from the bacteriological view point]. | 1976 | 785871 | |
| [sensitivity of the compensatory hyperthrophic rat-kidney against hematogenous bacterial damage]. | 1976 | 785868 | |
| [study of bacterial allergy in acute appendicitis by the method of leukocyte migration inhibition in vitro]. | under study was the effect of various bacterial allergens on the migration of blood leucocytes from capillaries in vitro in 23 patients with acute appendicitis and in 18 healthy individuals. bacterial allergens wound suppress leucocytes migration in all patients. most frequently, sensibilization to allergens of hemolytic staphylococcus and hemolytic streptococcus was found. in 4 healthy persons this methods indicated sensibilization to some allergens. the interaction of activity sensibilized ly ... | 1976 | 785785 |
| a rationale for intraperitoneally administered antibiotic therapy. | a satisfactory clinical response occurred in 96.7 per cent of 210 patients with proved bacterial peritonitis following appropriate surgical intervention and an antimicrobial regimen of 1 per cent cephalothin administered intraperitoneally, with supplementary antibiotics as indicated. instillation of cephalothin achieves the therapeutic benefits of high intraperitoneal levels with an antibiotic of broad activity and minimum toxicity and permits flexibility in the choice of additional antimicrobia ... | 1976 | 785645 |
| infections in the surgical departments of a teaching hospital in jerusalem. | surveillance of hospital-associated infections at the hadassah university hospital has been carried out since 1970. criteria for infection were defined and were monitored by trained nurse-epidemiologists, with the cooperation of the surgical staff. this report deals with the results of a prospective study of infections present on admission, and those acquired during hospitalization, in six surgical departments between january 1972 and june 1973. of the 7,339 patients discharged, 7.5% acquired an ... | 1976 | 783080 |
| [evaluation of diagnostic parameters in chronic recurrent urinary tract infection in children. iii. pyuria, hematuria, and proteinuria (author's transl)]. | pyuria, proteinuria and haematuria have been shown to be unreliable parameters for the diagnosis of bacteriuria in 171 children with 455 recurrences of chronic urinary tract infection. bacteriuria caused haematuria in 5%, proteinuria in 18% and even pyuria in only 47% of all instances. pyuria has been also found in 11% of sterile urines. the incidence of pyuria increases with the age of the children and depends on the type of the organisms, but the latter was true mainly in children with obstruc ... | 1976 | 782812 |
| [sisomicin versus gentamicin. a comparison of antibacterial and pharmacokinetic properties (author's transl)]. | in a comparison of the antibacterial in-vitro activity of sisomicin, gentamicin, and tobramycine, sisomicin showed a higher activity against e. coli, indole-positive proteus spp. and organisms of the klebsiella-enterobacter-serratia group, whereas tobramycine was superior against pseudomonas spp. however, the differences in activity between sisomicin and gentamicin were only within one step of dilution which is hardly sufficient to guarantee a basic superiority of one or the other preparation fo ... | 1976 | 782808 |
| [treatment of peritonitis within the scope septic shock with antibiotics]. | 1976 | 782801 | |
| [clinical trial of the antibacterial combination sulfamoxole/trimethoprin (cn 3123). fifth communication: comparison of two double-blind studies with cn 3123 undertaken for demonstration of its efficacy (author's transl)]. | two double-blind trials which, independently, revealed the same conclusion that there is no significant difference between the therapeutic effect of n1-(4,5-dimethyl-2-oxazolyl)-sulfanilamide (sulfamoxole) and 2,4-diamino-5-(3,4,5-trimethoxy-benzyl)-pyrimidine (trimethoprim) (cn 3123, neven, supristol) and a reference preparation, were compared with each other in respect of rating the therapeutic result. the authors discuss the greater occurrence of proteus pathogens at one trial centre, and its ... | 1976 | 782477 |
| [bacteria of the genus morganella]. | 1976 | 782106 | |
| [progress in the prevention and control of urologic complications of the cervix carcinoma. i. urinary tract infections]. | an investigation was made on patients with cervical carcinoma to test the efficiency of a general administration of antibiotics and chemotherapeutic drugs which are commonly used in urology. the study has been made to analyze the frequency of pathological findings in the urinary tract, in general, and, in particular, the pattern of bacteriological findings as well as antibiogramms at different times of carcinoma therapy. additionally, consideration was given to the bacteriological situation befo ... | 1976 | 782093 |
| [central venous long-term catheter as potential source of infection in the intensive therapy]. | 1976 | 782053 | |
| functional modifications and nuclear analogues of beta-lactam antibiotics--part i. | 1975 | 781739 | |
| [proteus l-cycle in flow microcultures]. | 1976 | 781488 | |
| [comparative characteristics of the biological properties of proteus varieties]. | 1976 | 781487 | |
| [formation of l-asparagine and l-glutamine deamidases by bacterial cultures]. | among studied 40 bacterial cultures, 17 strains catalysed hydroxylaminolysis of i.-asparagine and l-glutamine, and among these cultures seven strains belonged to the pseudomonas genus. extracts of the cells of ps. boreopolis 526 (mgu), ps. aurantiaca ibfm b-14, and ps. septica ibfm b-40 had the maximum deamidase activity during the stage of decelerated growth. the activity of l-asparaginase 2 was practically the same upon various ways of disintegration of the cells of ps. aurantiaca ibfm b-14: b ... | 1976 | 781474 |
| imidazo(1,2-c)pyrimidine nucleosides. synthesis and biological evaluation of certain 1-(beta-d-arabinofuranosyl)imidazo(1,2-c)pyrimidines. | the first chemical syntheses of the arabinosylhypoxanthine and arabinosylguanine analogues of the imidazo-[1,2-c]pyrimsdine series are described. condensation of trimethylsilyl-7-chloroimidazo[1,2-c]pyrimidin-5-one (1) with 2,3,5-tri-o-benzyl-alpha-d-arabinofuranosyl chloride (2) gave 7-chloro-1-(2,3,5-tri-o-benzyl-beta-arabinofuranosyl)imidazo[1,2-c]pyrimidin-5-one (3) which on catalytic dehalogenation furnished 1-(2,3,5-tri-o-benzyl-beta-d-arabinofuranosyl)imidazo[1,2-c]pyrimidin-5-one (4). am ... | 1976 | 781243 |
| antibacterial activity of ribostamycin on enterobacteriaceae. | the study of the inhibitory activity of ribostamvcin (vistamycin), an antibiotic derived from streptomyces ribosidificus, on 161 strains of gram-negative bacilli shows that the antibacterial spectrum of this antibiotic is identical to that of kanamycin. if controlled clinical studies confirm that ribostamycin is less toxic than kanamycin on the otovestibular system, this antibiotic will constitute a real therapeutic advance. | 1976 | 779802 |
| [in vitro effect of cephacetril and colistin combinations on klebsiella pneumoniae and proteus strains (author's transl)]. | in 14 out of 43 klebsiella pneumoniae strains (33%) the combination cephacetril-colistin showed a synergistic, in 11 strains (25%) an additive effect. in proteus strains no synergistic action was found. the combination was more likely to be synergistic or additive in strains requiring higher minimal inhibitory concentrations of cephacetril and colistin. most highly resistant klebsiella pneumoniae strains were synergistically inhibited by concentrations of both drugs, which can easily be obtained ... | 1976 | 779799 |
| clinical evaluation of commercial reagent strips for detection of significant bacteriuria in dogs and cats. | the reagent strip technique of quantitative urine culture was a satisfactory screening test for the detection of significant bacteriuria in dogs and cats. the reagent strip technique was found to be of almost equal sensitivity as the calibrated loop technique in identifying significant bacteriuria. significant bacteriuria was detected in 38 of 148 urine samples evaluated by the calibrated loop technique. of these 38 urine samples, significant bacteriuria was detected in 35 by the commercial test ... | 1976 | 779543 |
| inhibition of gill cilial activity and of proteus vulgaris motility as tests for aspirin idiosyncrasy. | aspirin ingestion is likely to result in severe asthmatic attacks in patients with aspirin idiosyncrasy. there is no in vitro test for the condition. gill cilia and proteus vulgaris motility studies showed no differences between asthmatics with aspirin idiosyncrasy and control patients. | 1976 | 779534 |
| [resistance to beta-lactam antibiotics and aminoglycosides in gram negative bacteria. 1. molecular and genetic characterization of r-factors (author's transl)]. | with frequent use of aminoglycoside antimicrobials and beta-lactam antibiotics in hospitals in the last few years, the number of bacterial strains resistant to these chemotherapeutics increased. lately, strains of e. coli, klebsiella, enterobacter, serratia, proteus and pseudomonas resistant to many antimicrobials (ampicillin, carbenicillin, cephalothin, chloramphenicol, gentamycin, tobramycin, sisomycin, neomycin, paromomycin, kanamycin, streptomycin, spectinomycin, tetracycline, sulphonamides) ... | 1976 | 779353 |
| [treatment with gentamicin in 22 cases of epidemic acute enteritis due to gram-negative germs in a neonatal intensive care department]. | 1975 | 778577 | |
| [elimination of multiple resistance of enteric bacteria by acriflavine and experiments with trimethoprim for the same purpose]. | 1975 | 778555 | |
| a continuous study of morphological phase in the swarm of proteus. | continuous study, at intervals of 1 h, on the advancing edge of the swarm of proteus vulgaris confirms that this is almost permanently composed of elongated swarmers, and that short, non-swarming forms arise in the interior of the culture where motion has already ceased. previous errors have probably arisen from inaccurate sampling. | 1976 | 778391 |
| the importance of prolonged incubation for the synthesis of dimethylnitrosamine by enterobacteria. | tests with 140 strains representing escherichia coli, klebsiella aerogenes, k. ozaenae, proteus mirabilis, p. vulgaris, p. rettgeri and p. morganii in a defined medium supplemented with 0-09m dimethylamine (dma) and 0-1m potassium nitrate showed that at least 89% of the 136 strains able to reduce nitrates produced up to 9mm dimethylnitrosamine (dmn) in 70h at 37 degrees c. four nitratase-negative strains produced dmn from dma in the presence of sodium nitrate. prolonged incubation was the most i ... | 1976 | 778390 |
| purification and properties of the alpha2beta2 complex of tryptophan synthetase of proteus mirabilis. | a procedure is described for the purification of the tryptophan synthetase alpha2beta2 complex from cell extracts of proteus mirabilis. a 30-fold purification was achieved with an overall yield of about 23% and a specific activity of 1,600. the complex can be dissociated and the subunits isolated in a pure form. the complex can be reconstituted from the isolated subunits to regain the initial activity. the alpha and beta2 subunits of the tryptophan synthetase complex of p. mirabilis are not sign ... | 1976 | 776977 |
| ecori restriction endonuclease map of the composite r plasmid nr1. | a physical map of the composite r plasmid nr1 has been constructed using specific cleavage of deoxyribonucleic acid (dna) by the restriction endonuclease ecor-. digestion of composite nr1 dna by ecori yields thirteen fragments. the six largest fragments (designated a to f) are from the resistance transfer factor component that harbors the tetracycline resistance genes (rtf-tc). the seven smallest fragments (designated g to m) are from the r-determinants component that harbors the chloramphenicol ... | 1976 | 776943 |
| evidence against the involvement of chemotaxis in swarming of proteus mirabilis. | nonswarming and nonchemotactic mutants of proteus mirabilis were isolated after mutagenesis with n-methyl-n'-nitro-n-nitrosoguanidine or ultraviolet light. these mutants were used in experiments to determine if chemotaxis is involved in the swarming of p. mirabilis. nonchemotactic mutants failed to form chemotactic bands in a semisolid casein hydrolysate medium, yet they swarmed on the same medium containing 1.5% agar. nonswarming mutants were attracted towards individual amino acids and compone ... | 1976 | 776927 |
| relationship between antibiotic consumption and frequency of antibiotic resistance of four pathogens--a seven-year survey. | 1976 | 776921 | |
| clinical experience with indanyl carbenicillin in urinary tract infections. | a trial was carried out in 30 patients to assess the effectiveness of indanyl carbenicillin in acute or chronic urinary tract infections, many of which were complicated by a pathological urological or medical condition. in all patients, infection was due to a single species of pathogen: e. coli (19), proteus (6), and pseudomonas (5). oral doses of 1 g indanyl carbenicillin were given 6-hourly for an average of 10 days. results showed a clinical and bacteriological cure in 13 (43.8%) patients. in ... | 1976 | 776540 |
| activation of the complement system during infections due to gram-negative bacteria. | 1976 | 776471 | |
| [effect of cephalothin and cephalexin on various bacterial species isolated from biological material in the regional hygienic station bratislava]. | 1976 | 776399 | |
| [inhibition of bacterial agmatinase by several aliphatic diamines]. | about 10 amino derivatives, capable to inhibit agmatinase of proteus vulgaris, are found. hexamethylenediamine was found to possess the highest inhibitory effect among diamines, the inhibitory constant being 2.5 mm. the substitution of an amino group for methyl one in a diamine increased its inhibitory effect. the presence of carboxyl group in the molecule of a reagent resulted in a complete elimination of the inhibitory effect (putrescine-ornithine and cadaverine-lysine pairs were tested). the ... | 1976 | 776236 |
| [efficacy of the carbenicillin-cephaloridine association]. | 1975 | 776102 | |
| transferable and non-transferable drug resistance in enteric bacteria from hospital and from general practice. | drug resistance to 8 different antibiotics in enterobacteriaceae isolated from different hospitals and two groups of general practitioners was studied. escherichia coli dominated among the 632 strains investigated. drug resistance was found in 62% of the 512 hospital strains and in 38% of the 120 strains from general practice. multiple resistance was common especially in strains from hospital. r factors was found in 23% of the 317 drug-resistant strains from hospital and in 11% of the 46 drug-re ... | 1976 | 775619 |
| [proticin types of proteus mirabilis strains isolated from various environments]. | 1976 | 775565 | |
| [new data on the karyology of formation of l forms of proteus vulgaris]. | the growth and development of the proteus vulgaris culture as well as the process of formation of its l-forms were studied following the pitzurra method on slides covered with an agar layer. the latter were kept upon inoculation in a vertical position in a moist chamber at 37 degrees c. on fixed and stained after giemza preparations, it was possible to follow the consecutive stages of the cytoplasmic "hernia" formation due to the local disruption of the bacillary cell wall. it was easy to disern ... | 1975 | 775258 |
| bacterial mastitis in guinea pigs. | necropsy of 37 guinea pigs revealed mastitis to be the primary cause of death in 70% of these animals. epidemiologic study failed to establish correlation between age, parity, or litter size and the onset of mastitis. the disease did not appear to be contagious. although mastitis frequently developed during lactation, survivability of offspring was unaffected. the agent most consistently isolated from affected mammary glands was escherichia coli (17 of 37). other isolates in decreasing order of ... | 1976 | 775191 |
| clinical experience with gentamicin in complicated urinary tract infections (author's transl)]. | gentamicin 40 mg was intramuscularly admininistered two times daily to 15 patients with complicated urinary tract infections. the results are as follows 1. the clinical efficacy of gentamicin was excellent in 12 cases (80.0%), good in 2 cases (13.3%) and null in 1 case (6.7%). the effective rate was 93.3%. 2. bacteria disappeared in 16 strains (84.2%), colonized in 3 strains (15.8%) out of 19 isolates. 3. bun, got and gpt values were determined before and after gm administration, and no signific ... | 1976 | 775144 |
| [revaluation of gentamicin in laboratory and clinical studies (author's transl)]. | the mic of gentamicin and other antibiotics against clinical isolates was determined, and the following sensitivity distribution was obtained. a) against 54 strains of staphylococcus aureus, gm had the lowest mic, followed by tob, dkb, bb-k8 in order. the distribution range of 0.1-6.25 mug/ml was noted with gm. the peak of mic was 1.56 mug/ml. b) against 54 strains of e. coli, the lowest mic was obtained with gm, and 53 strains (98%) were in the range of 0.4-6.25 mug/ml. the peak of mic was 3.12 ... | 1976 | 775143 |
| differentiation of proteus mirabilis by bacteriophage typing and the dienes reaction. | a provisional typing schema based on sensitivity to 23 bacteriophages has been established for proteus mirabilis. seventy-three bacteriophages were isolated on strains of p. mirabilis (64), p. vulgaris (1), p. morganii (7), and p. rettgeri (1), but those isolated on p. mirabilis were the most useful in differentiating other strains of . mirabilis. from the 73 phages studied, the best 23 were chosen by computer analysis for the provisional system, which was then used to study p. mirabilis infecti ... | 1976 | 773962 |
| [microflora of the pus of lactation mastitis patients and its sensitivity to a series of antibiotics]. | the etiological picture of lactation mastitis and sensitivity of its causative agent to some antibiotics were studied. mostly microbial associations were isolated from the patients. pathogenic staphylococci typed mainly by the phages of group i predominated among the isolates. in addition the strains of proteus, pseudomonas, e. coli and others were isolated from the pus of the mastitis cases. sensitivity of the microflora to some antibiotics was studied. it was found that most of the causative a ... | 1975 | 773286 |
| proteus species isolated from human eyes. | of 34 species of proteus isolated from human eyes, 29 (85%) were p. mirabilis and five (15%) were p. morganii. in vitro antibiotic sensitivity studies showed that gentamicin best controlled both p. mirabilis and p. morganii of all the antibiotics tested. in vivo tests on experimental proteus infections of rabbit coreas, treated with gentamicin and tobramycin, yielded comparable clinical results, but gentamicin was more effective in eliminating the organism from the experimental lesions. | 1976 | 773185 |
| beta-lactam antibiotics alone or in combination with gentamicin for therapy of gram-negative bacillary infections in neutropenic patients. | this study was initiated to determine whether antibiotic combinations are superior to single antibiotics for the treatment of gram-negative bacillary infections in neutropenic patients. twenty-six patients with pseudomonas and proteus infections received either carbenicillin or carbenicillin, plus gentamicin. the cure rates were 83 and 93 per cent, respectively. twenty-three patients with infections caused by other gram-negative bacilli received either cephalothin plus gentamicin. the cure rates ... | 1976 | 773180 |
| cephazolin: a comparison to ampicillin in respiratory and urinary infections with dosage regulation by a nomogram. | cephazolin sodium was shown to be as effective as ampicillin in the treatment of respiratory and urinary system infections in patients who were infected with susceptible organisms and had a much less troublesome side reaction rate of hypersensitivity type. in addition, it was found that predictable blood levels of cephazolin could be obtained in patients with renal failure when dosage was regulated according to a nomogram calculated from the patient's serum half-life based on clearance of creati ... | 1976 | 772809 |
| the prevalence of ampicillin, cephalosporin and sulphonamide resistance amongst urinary tract pathogens. | a total of 2,031 clinical isolates of gram negative bacilli was obtained from hospitals in 4 centres and these cultures were tested for resistance to ampicillin, cephazolin and sulphonamide. ampicillin and sulphonamide resistance in outpatients ranged from 15 to 28 per cent of e. coli strains and 4 to 11 per cent of proteus mirabilis strains. resistance to cephazolin in outpatients ranged from 0 to 3 per cent of e. coli and 0 to 6 per cent of proteus mirabilis. resistance patterns for e. coli, p ... | 1976 | 772807 |
| [experience in use of amoxicillin for treatment of acute cystitis (author's transl)]. | seventeen cases of acute simple cystitis were treated by oral administration of amoxicillin at a daily dose of 1.0 g (250 mg x 4 in a day) for consecutive 7 days, and the following results were obtained. 1. amoxicillin was remarkably effective in 11 of total 17 cases, effective in 2, slightly effective in 2 and non-effective in 2. 2. in terms of effect against isolated bacteria, amoxicillin was remarkably effective against 6 of 11 strains of e. coli, effective against 2, slightly effective again ... | 1976 | 772243 |
| intra-species tranduction with proteus mirabilis high frequency transducing phages. | the properties of three additional proteus mirabilis hosts for the high frequency transducing (het) phages 5006mhftkappa and 5006mhftak are described. the phages transduce resistance to kanamycin and to ampicillin plus kanamycin, respectively, and were produced by ultraviolet induction of derivatives of p. mirabilis strain pm5006. strain pm804 could not be shown to adsorb the phages although it yielded a few transductants. all transductants, even those produced at low multiplicities of phage inp ... | 1976 | 772163 |
| derivation and properties of f-prime factors in escherichia coli carrying nitrogen fixation genes from klebsiella pneumoniae. | a his+ nif+ escherichia coli k12, hfr strain (unf43) was constructed by an intergeneric mating between a klebsiella pneumoniae donor strain (hf3) and a his-hfr e. coli strain (sbi824) which transfers his as an early marker. an f-prime nif plasmid, fn39, carrying genes which correspond to the e. coli chromosomal region, metg gnd his shia, but excluding purf and arod, was isolated from unf43. translocation of carbenicillin resistance genes from a p-type r-factor, r68, to fn39 increased the stabili ... | 1976 | 772161 |
| tryptophan operon regulation in interspecific hybrids of enteric bacteria. | we examined tryptophan regulation in merodiploid hybrids in which a plasmid carrying the trp operon of escherichia was introduced into trp mutants of other enteric genera, or in which a plasmid carrying the trpr+ (repressor) gene of e. coli was transfered into fully constitutive trpr mutants of other genera. in these hybrids the trp operon of one species is controlled by the repressor of a different species. similar investigations were possible in transduction hybrids in which either the trp ope ... | 1976 | 770450 |
| the effect of imidazole on the disruption of the blood-aqueous barrier in the rabbit eye. | the aqueous flare (af) of an intact rabbit eye was measured by a photoelectrical instrument and the intraocular pressure by vibration tonometry. prior treatment with imidazole given intraperitoneally noticeably inhibited the disruption of the blood-aqueous barrier in rabbit eyes induced by topical prostaglandin e2 (pge)2, topical arachidonic acid (aa), infrared irradiation of the iris, endotoxin of proteus mirabilis given intravenously, and alpha-melanocyte-stimulating hormone (alpha-msh) given ... | 1976 | 770385 |
| sequence studies on the 5s rna of proteus vulgaris: comparison with 5s rna of escherichia coli. | we have studied the sequence of 5s ribosomal rna of proteus vulgaris. although several doubts remain, it seems that no more than 8 per cent of the nucleotides differ from those of escherichia coli 5s rna. of the ten bases differing from escherichia coli 5s rna sequence, three changes take place in one of the six positions which are known as intercistronic mutation points in escherichia coli 5s rna. we can conclude that they are "hot spots" of mutation. | 1975 | 769842 |
| comparative study of the 16s rna's of escherichia coli and proteus vulgaris. | we have studied the primary structure of 16s ribosomal rna from proteus vulgaris. the oligonucleotides containing methylated bases appeared to be the same as those of escherichia coli, with one exception. we have also studied the base composition of the oligonucleotides obtained after t1 ribonuclease digestion of 16s rna. on the basis both of their position on the fingerprint and of their pancreatic ribonuclease analyses, approximately 25 appeared to differ from those found in the e. coli t1 fin ... | 1975 | 769841 |
| in vitro studies of cefamandole. | cefamandole is a new cephalosporin antibiotic that was tested in vitro against 540 clinical isolates of gram-positive cocci and gram-negative bacilli. a concentration of 0.39 mug/ml inhibited 95% of the isolates of staphylococcus aureus. a concentration of 6.25 mug/ml inhibited over 90% of the isolates of proteus mirabilis and escherichia coli, 69% of the isolates of klebsiella pneumoniae, and 31% of the isolates of indole-positive proteus spp. and enterobacter spp. it was active against most ce ... | 1976 | 769679 |
| effect of resistance possessed by certain enteric microorganisms upon orally inoculated salmonella. | mice shedding aerobic gram-negative microorganisms with high levels of resistance to tetracycline were orally inoculated with salmonella typhimurium. levels of resistance of salmonella isolated from tissue were shown not to be increased and, in most instances, were lower than preinoculation levels. | 1976 | 769613 |
| tobramycin in chronic recurrent urinary tract infections. | a total of 32 adult patients of both sexes with chronic recurring urinary tract infections were treated with tobramycin in a daily dose of 1.2 mg/kg of body weight. they were randomly allocated to receive the drug at 8 or 12 hour intervals by intramuscular injection. the overall immediate disappearance of bacteriuria after therapy was 78.1 per cent; 15 days later, the cure rate dropped to 60 per cent. there was no difference between the two schedules tested. tolerance to tobramycin was excellent ... | 1976 | 769550 |
| acute infectious arthritis. a review of patients with nongonococcal joint infections (with emphasis on therapy and prognosis). | the clinical course of 59 patients with acute nongonococcal septic arthritis has been reviewed with special emphasis on the changing bacterial spectrum in recent years. the results of treatment were dependent on various factors, including the specific microbial agent and host defenses. treatment should include parenteral antibiotics and drainage with needle aspiration, except in hips which should be surgically drained. successful therapy requires rapid initiation of treatment and ongoing assessm ... | 1976 | 769545 |
| [clostridial and non-clostridial gas gangrene. apropos of 31 cases]. | 1975 | 769461 | |
| [lipid composition of cellular systems following viral infection of the upper respiratory tract. i. study of lipid composition on the model of different types of bacteria]. | 1975 | 769342 | |
| [study of rapid methods for determining the biochemical properties of microorganisms. i]. | some express methods were tested comparatively in determining the biochemical properties of certain microorganisms in order to recommend the most effective of them to be used in the laboratory. described is a disk method with which the term of cultivation is shortened by one to 5 hours, and the results obtained are clear and well distinctive. the data obtained are almost comparable with the results achieved using the methods provided in the bulgarian state standard. it is suggested to adopt the ... | 1976 | 769305 |
| nonstaphylococcal bacteria in renal cortical abcess. | five cases of renal cortical abscess are presented, of which four yielded gram-negative pathogens. along with a review of the recent literature, this suggests that nonstaphylococcal bacteria are a more common cause of this disease. | 1976 | 769286 |
| the bacterial flora of the female rat genital tract. | a study of the genital microflora in virgin female rats of reproductive age has demonstrated that alpha and nonhemolytic streptococci, pasteurella pneumotropica, diphtheroid bacilli, staphylococcus epidermidis, and proteus mirabilis are the predominant genital organisms. the ph of the rat vagina was demonstrated to be near neutrality. it is suggested that the higher ph in the rat vagina as compared to the human vagina may account for some of the differences between human and rat genital microflo ... | 1976 | 768992 |
| the isolation and partial characterization of a new restriction endonuclease from providencia stuartii. | we describe the isolation of a new class 2 restriction endonuclease from providencia stuartii 164. using the procedure of osmotic shock treatment, we have partially purified this enzyme (pst 1) and have begun preliminary work to characterize its specificity and requirements. pst 1 requires mg++ as the only cofactor and produces more than 18 cleavages in wild type lambda. we have determined the location of 7 of these cleavages by the use of deletion and insertion mutants of lambda. | 1976 | 768923 |
| transduction of leucine auxotrophs of proteus mirabilis to prototrophy or antibiotic resistance by p. mirabilis high frequency transducing bacteriophages. | high frequency transducing (hft) phages 5006mhftk and 5006mhftak for kanamycin or ampicillin plus kanamycin resistance, derived from proteus mirabilis strains pm5006(r394) and pm5006(r394) respectively, transduced (at low multiplicities of infection, m.o.i.) antibiotic resistance and prototrophy to pm5006 leu-i at high frequency. simultaneous transduction of these markers occurred at very much lower frequencies. the latter result was correlated with the proportion of multiply-infected bacteria w ... | 1976 | 768411 |
| epidemics of nosocomial urinary tract infection caused by multiply resistant gram-negative bacilli: epidemiology and control. | 1976 | 768384 | |
| [antibiotic activity in relation to various proteus species]. | 1975 | 767133 | |
| the linkage of lysine in the o-specific chains of proteus mirabilis 1959. | lipopolysaccharides of qualitatively identical but quantitatively different sugar composition were extracted from proteus mirabilis strain 1959. the lipopolysaccharide with the higher percentage of typical o-specific constituents was subjected to partial acid hydrolysis. an oligosaccharide b22 was separated by paper chromatography and electrophoresis. it was found to be composed of equimolar amounts of d-galacturonic acid, d-galactosamine and l-lysine. dinitrophenylation of the oligosaccharide a ... | 1976 | 767106 |
| inhibition of cell wall synthesis by sulfonamides and trimethoprim. | the hypothesis that defective cell wall synthesis seems to represent a final common pathway of drug-induced injury either within the bacterial cell or on its surface was supported by two different findings: (1) sulfamethoxazole and trimethoprim, either alone or in combination, induced morphological findings in various escherichia coli and proteus mirabilis strains identical to those found after incubation with so-called cell-wall-active antibiotics (e.g., penicillin) and (2) cell-wall-defective ... | 1976 | 767064 |
| the primary response to lps and lipid a of p. mirabilis at the cellular level. | 1975 | 766920 | |
| [antibody response to bacterial antigens administered orally]. | 1975 | 766784 | |
| [multiplication and changes in the virulence of proteus vulgaris in milk]. | 1975 | 766576 | |
| the periurethral aerobic flora in girls highly susceptible to urinary infections. | after the age of 5 years, normal children have but few aerobic gram-negative rods periurethrally. this study examines whether there is an abnormal periurethral colonization in urinary tract infection-prone girls during infection-free intervals, indicating a defective local defence. in 13 girls with a history of recurrent infection, daily bacterial samples were obtained from the periurethral area and from urine. sampling continued until an infection eventually occurred. seven girls contracted a u ... | 1976 | 766563 |
| the periurethral aerobic bacterial flora in healthy boys and girls. | the present study was undertaken to provide information about the presence of bacterial flora in the periurethral region of healthy children and its variation with age and sex. it was intended as a basis for subsequent studies in individuals prone to urinary tract infection. quantitative methods were used for bacteria sampling and culture. the study included 394 girls and 305 boys from birth to 16 years. during the first few weeks of life a massive aerobic bacterial flora (e. coli, enterococci, ... | 1976 | 766562 |
| [condition of microflora of the nasopharynx in immunization with live influenza vaccine for oral administration]. | the authors present data concerning the state of the microflora of the nasopharynx in the immunization of adults and schoolchildren with the living influenza vaccine for oral administration. during the vaccinal process there occurred qualitative changes in the microbial pattern of the nasopharynx and a reduction in the level of the salivary lysozyme. the most pronounced changes were seen after the first vaccination, when the seeding efficiency of the pathogenic staphylococcus the e. coli and the ... | 1975 | 766528 |
| [detection, quantitative calculation and identification of bacteria of the proteus genus in objects of the environment]. | the author suggests a complex of nutrient media which aid in detection, quantitative recording and identification of bacteria belonging to proteus genus and also of the species included into this genus, as well as of the biochemically similar bacteria. the complex of the media constitutes a complete cycle of study: the first stage-fluid enrichment medium, the second stage-isolation and preliminary identification on a hard differential medium with a narrow directed action, and the third stage-det ... | 1975 | 766522 |
| [evaluation of bacteriostatic value of gentamicin in cases of significant bacteriuria]. | 1976 | 766419 | |
| [impairments of lipid metabolism in liver, kidney and heart tissues of mice infected with proteus vulgaris]. | intraperitoneal administration of proteus vulgaris living culture of various age (12 hrs and one day) caused impairments in lipid metabolism in mice liver, kidney and heart tissues. the one day-old culture was more toxic. the impairment in lipid metabolism was manifested as distinct increase in cholesterol content in liver tissue and kidney and a decrease in phospholipid content in liver, kidney and heart tissues. these changes were accompanied by an increase in content of sialic acids in liver ... | 1975 | 766398 |
| [urinary infections following bladder catheterization]. | the incidence and the prophylaxis of urinary tract infection following bladder catheterization have been studied in 142 patients admitted for voiding cystourethrography (vcu). 71 children received a prophylactic treatment of 2 mg/kg nitrofurantoin daily for 4 days, while 71 received no treatment following bladder catheterization. bacteriologic examination of the urine 4-9 days after catheterization showed significant bacteriuria in 5 untreated children. the germs responsible were e. coli, proteu ... | 1975 | 766175 |
| [genetical study on cointegrate (author's transl)]. | 1975 | 766081 | |
| photodynamic alterations of the cell envelope of proteus mirabilis and their repair. | 1975 | 766020 | |
| [indanyl carbenicillin in the treatment of urinary tract infections due to difficult urological organisms (author's transl)]. | fifty in-patients suffering from chronic urinary tract infections with underlying urological diseases received the oral carbenicillin preparation indanyl carbenicillin (short term carindacillin) for 10 days in a dosage of 1 g q.i.d. the therapy results were objectified by blood and urine tests performed prior to and after treatment. indanyl carbenicillin led to a sterile urine in nearly 60% of the patients; in about 85% of the cases the primary organism was eliminated. the drug was particularly ... | 1976 | 765706 |
| [bactericidal activity of serum and chemotherapy in sensitive and resistant exciter (author's transl)]. | comparing examinations with ampicillin sensitive and resistant bacteria-strains show that the bactericidal activity of serum is dependent on the bacteria-strains, on the ampicillin sensitivity of the particular exciter and on the number of bacteria/ml (germ count). bactericide effect could always be obtained with sensitive strains as a result of additional chemotherapy. with several resistant strains a bactericide effect could not be obtained in this case the continuous optimal ampicillin addit ... | 1975 | 765704 |