Publications

TitleAbstractYear
Filter
PMID(sorted descending)
Filter
non-susceptibility trends among enterobacteriaceae from bacteraemias in the uk and ireland, 2001-06.enterobacteriaceae are common agents of bacteraemia, with escherichia coli accounting for 20% of the cases. reflecting this importance, members of the family constitute 4 of the 12 collection groups in the british society for antimicrobial chemotherapy (bsac) bacteraemia surveillance programme.200818819979
antibacterial activity of the fruits of iranian torilis leptophylla against some clinical pathogens.the aim of this study was to examine the antimicrobial activity of the methanolic extract of torilis leptophylla was tested on eleven bacteria (bacillus anthracis, bacillus subtilis, bacillus pumilus, staphylococcus aureus, bacillus licheniformis, brucella melitensis, escherichia coli, salmonella typhi, proteus mirabilis, bordetella bronshiseptica and pseudomonas aeruginosa). tested extract was effective against all bacteria but not b. subtilis. consequently, the ethanolic extract had antibacter ...200818819541
inhibitory effects of sage extract on the growth of enteric bacteria.antibacterial activity of sage extract at concentrations of 0.1, 0.05, 0.025, 0.0125, 0.00625, 0.003125, 0.00156, 0.0005 and 0.00025 g dl(-1) against salmonella typhi, shigella sonnei, s. flexneri, proteus vulgaris, staphylococcus aureus, etec escherichia coli and pseudomonas aeruginosa was evaluated. susceptibility testing of bacterial strains against 18 antibiotics was also performed for comparison. the results showed that p. aeruginosa and etec e. coli were completely resistant to sage extrac ...200818817180
molecular identification of streptococcus equi subsp. equi and streptococcus equi subsp. zooepidemicus in nasal swabs samples from horses suffering respiratory infections in iran.the objective of this study was to evaluate the existence of streptococcus equi subsp. equi and streptococcus equi subsp. zooepidemicus as probable agents associated with naturally occurring infection of the equine upper respiratory disease in mashhad area. nasal swabs samples from thirty horses with upper respiratory tract infections were collected. the bacteria isolated and identified were streptococcus equi subsp. equi (1 isolate), streptococcus equi subsp. zooepidemicus (25 isolates), pasteu ...200818817175
congenital lipomatous overgrowth, vascular malformations, and epidermal nevi (clove) syndrome: cns malformations and seizures may be a component of this disorder.a newborn girl was found to have a massive lymphatic truncal vascular malformation with overlying cutaneous venous anomaly associated with overgrown feet and splayed toes. these manifestations comprise the recently described clove syndrome. she also had cranial asymmetry and developed generalized seizures, which were treated with anticonvulsants. cranial ct showed encephalomalacia, widening of the ventricles and the sulci, hemimegalencephaly (predominantly white matter) and partial agenesis of c ...200818816642
genetic and phenotypic heterogeneity in the pten hamartoma tumour syndrome.germline pten (phosphatase and tensin homologue deleted on chromosome ten) mutations predispose to phenotypically diverse disorders that share several overlapping clinical features: cowden syndrome, bannayan-riley-ruvalcaba syndrome, proteus syndrome and proteus-like syndrome, collectively classified as pten hamartoma tumour syndrome (phts). the meticulous acquisition and documentation of phts phenotypic data at different levels and the profiling of the plethora of genetic changes in pten and ot ...200818794875
lipase-catalyzed production of a bioactive fatty amide derivative of 7,10-dihydroxy-8(e)-octadecenoic acid.enzymatic syntheses of fatty amides are of considerable interest due to their wide ranging industrial applications in detergents, shampoo, cosmetics and surfactant formulations. amidation reaction of candida antarctica lipase b (calb) was investigated for direct amidation of carboxylic acid in organic solvent. calb-mediated production of a novel secondary amide was carried out by reacting the hydroxy oleic acid derivative, 7,10-dihydroxy-8(e)-octadecenoic acid (dod), with n-methylethanol amine i ...200918793843
a prospective study of ceftriaxone treatment in acute pyelonephritis caused by extended-spectrum beta-lactamase-producing bacteria.much controversy exists as to whether cephalosporin treatment is appropriate for infections caused by esbl-producing organisms because no randomized controlled studies have been performed.200818788687
presentation, treatment, and clinical course of otogenic lateral sinus thrombosis.otogenic lateral sinus thrombosis (olst) is almost always associated with other complications of chronic otitis media (com) and did not present a distinct clinical expression. in our experience, olst exhibits a benign course if the underlying disease is controlled. mastoidectomy in combination with broad-spectrum antibiotics provided effective treatment. anticoagulation therapy is no longer used routinely. recanalization is rare and is independent of the use of anticoagulants.200918781447
synthesis, structure and biological activity of copper(ii) complexes of 4-(2-pyridylmethyl)-1,7-dimethyl-1,4,7-triazonane-2,6-dione and 4-(2-pyridylethyl)-1,7-dimethyl-1,4,7-triazonane-2,6-dione.four mononuclear copper(ii) complexes 1-4 have been synthesized with two new n-functionalized macrocyclic ligands l(1) and l(2). all complexes are well characterized by various spectroscopic techniques, elemental analyses and conductivity measurements. results suggest that cu(ii) ion has n(2)o coordination from ligand and s(2) from two coordinated solvent molecules (sch(3)cn for 1 and 3 while ch(3)oh for 2 and 4). the crystal structure of a representative complex 3 strengthen the proposed formul ...200918775587
[lower urinary tract infections: bacterial epidemiology and recommendations].lower urinary tract infection remains frequent particularly in women, despite improvement in therapeutic means. it seems likely to revisit bacterial epidemiology and therapeutic available strategies. to analyze elements in presence i.e. infecting bacteria and antibiotics still active or identification of acquired resistance mechanisms should permit to establish the evolution during the last 10 years. the study shows that bacterial epidemiology in urinary tract infection has not changed significa ...200818773847
prevalence and mechanisms of broad-spectrum beta-lactam resistance in enterobacteriaceae: a children's hospital experience.the objective of this study was to investigate the trends and patterns of resistance in beta-lactamase-producing members of the family enterobacteriaceae in a children's hospital over a 9-year period (1999 to 2007). clinically significant isolates of the enterobacteriaceae were screened for patterns of broad-spectrum resistance to beta-lactams. the strains likely to be resistant were subsequently confirmed by an inhibitor-based disc test. the plasmid-mediated resistance determinants in these iso ...200818765688
bacillus proteus septicemia. 193318742542
purple urine bag syndrome. 200818725621
zapa, a virulence factor in a rat model of proteus mirabilis-induced acute and chronic prostatitis.our knowledge of pathogenesis has benefited from a better understanding of the roles of specific virulence factors in disease. to determine the role of the virulence factor zapa, a 54-kda metalloproteinase of proteus mirabilis, in prostatitis, rats were infected with either wild-type (wt) p. mirabilis or its isogenic zapa(-) mutant kw360. the wt produced both acute and chronic prostatitis showing the typical histological progressions that are the hallmarks of these diseases. infection with the z ...200818725420
urinary infections due to multi-drug-resistant escherichia coli among persons with hiv disease at a tertiary aids care centre in south india.while the spectrum of opportunistic infections due to hiv infection has been widely discussed, there are very limited data available in south india on certain incident infections especially urinary tract infections (uti) in hiv-infected subjects.200818724067
regioselective synthesis and antimicrobial screening of novel ketocarbazolodispiropyrrolidine derivatives.a series of novel dispiropyrrolidine derivatives have been synthesized through 1,3-dipolar cycloaddition reaction of azomethine ylide generated from sarcosin and di/tri ketone with the dipolarophile (e)-2-arylidine-1-keto-carbazoles. the cycloadducts ketocarbazalo spiro n-methyl pyrrolidines showed the most interesting antimicrobial activity at lower concentration.200918722036
[antimicrobial resistance of uropathogens among outpatients, 2000-2004].a retrospective study based on the electronic database of a university hospital was carried out to investigate the prevalence of etiological agents and their susceptibilities to antibiotics, among adult outpatients (> 18 years old) with urinary tract infections. nine hundred and fifty-seven positive urine cultures were identified between january 2000 and december 2004. escherichia coli, proteus mirabilis and klebsiella sp were the three principal bacterial etiological agents. trimethoprim-sulfam ...200818719808
effect of triclosan on the formation of crystalline biofilms by mixed communities of urinary tract pathogens on urinary catheters.the crystalline bacterial biofilms that encrust foley catheters compromise the care of many elderly and disabled patients. the aim of this study was to examine whether the biocide triclosan can prevent encrustation by the mixed flora of uropathogens that commonly infect patients undergoing long-term catheterization. models of the catheterized bladder were inoculated with communities of organisms isolated from patients who were experiencing catheter blockage. the catheter retention balloons were ...200818719184
identification of virulence determinants in uropathogenic proteus mirabilis using signature-tagged mutagenesis.the gram-negative bacterium proteus mirabilis causes urinary tract infections (utis) in individuals with long-term indwelling catheters or those with functional or structural abnormalities of the urinary tract. known virulence factors include urease, haemolysin, fimbriae, flagella, dsba, a phosphate transporter and genes involved in cell-wall synthesis and metabolism, many of which have been identified using the technique of signature-tagged mutagenesis (stm). to identify additional virulence de ...200818719175
a novel biosorbent for dye removal: extracellular polymeric substance (eps) of proteus mirabilis tj-1.this paper deals with the extracellular polymeric substance (eps) of proteus mirabilis tj-1 used as a novel biosorbent to remove dye from aqueous solution in batch systems. as a widely used and hazardous dye, basic blue 54 (bb54) was chosen as the model dye to examine the adsorption performance of the eps. the effects of ph, initial dye concentration, contact time and temperature on the sorption of bb54 to the eps were examined. at various initial dye concentrations (50-400 mg/l), the batch sorp ...200918718709
antibacterial activity of halogenated sesquiterpenes from malaysian laurencia spp.during our studies on malaysian laurencia species, brominated metabolites, tiomanene, acetylmajapolene b, and acetylmajapolene a were isolated from an unrecorded species collected at pulau tioman, pahang along with known majapolene b and majapolene a. acetylmajapolene a was a mixture of diastereomers as in the case of majapolene a. tiomanene may be a plausible precursor for acetylmajapolenes b and a. in addition, three known halogenated sesquiterpenes and two known halogenated c(15) acetogenins ...200818718619
design, synthesis, and evaluation of novel organophosphorus inhibitors of bacterial ureases.a new group of organophosphorus inhibitors of urease, p-methyl phosphinic acids was discovered by using the structure based inhibitor design approach. several derivatives of the lead compound, aminomethyl(p-methyl)phosphinic acid, were synthesized successfully. their potency was evaluated in vitro against urease from bacillus pasteurii and proteus vulgaris. the studied compounds constitute a group of competitive, reversible inhibitors of bacterial ureases. obtained thiophosphinic analogues of th ...200818717581
nationwide surveillance of antimicrobial resistance among enterobacteriaceae in intensive care units in taiwan.to determine the antimicrobial resistance profiles among clinical isolates of enterobacteriaceae in taiwanese intensive care units (icus), a national surveillance of antibiotic resistance among important enterobacteriaceae was conducted from september 2005 through november 2005 at the icus of ten major teaching hospitals in taiwan. a total of 574 enterobacteriaceae isolates recovered from various clinical samples of our icu patients were submitted for in vitro test. minimum inhibitory concentrat ...200918716805
catheterized and non-catheterized urinary tract infections among patients attended at jimma university teaching hospital, southwest, ethiopia.prospective cross sectional study was undertaken to assess the bacterial profile and antimicrobial resistance pattern of catheterized urinary tract infection in comparison with non-catheterized uti in jimma university teaching hospital, southwest, ethiopia.200818711990
papx, a p fimbrial operon-encoded inhibitor of motility in uropathogenic escherichia coli.motility and adherence are two integral aspects of bacterial pathogenesis. adherence, often mediated by fimbriae, permits bacteria to attach to host cells and establish infection, whereas flagellum-driven motility allows bacteria to disseminate to sites more advantageous for colonization. both fimbriae and flagella have been proven important for virulence of uropathogenic escherichia coli (upec). reciprocal regulation is one mechanism by which bacteria may reconcile the contradictory actions of ...200818710869
nasal dermoid sinus cyst in a shih tzu. 200818708657
hemoperitoneum increases the incidence of bacterial translocation.severe hemorrhage may induce bacterial translocation (bt) from the bowel. presence of hemoperitoneum is supposed to further increase the incidence of bt.200818705287
flavonoids from pterocaulon alopecuroides with antibacterial activity.three flavonoids, (2 r,3 r)-5,4'-dihydroxy-3'- o-methyl-7-(gamma,gamma-dimethylallyloxy)dihydroflavonol 1, (2 r,3 r)-5,7,4'-trihydroxy-3'- o-methyl-6-(alpha,alpha-dimethylallyl)dihydroflavonol 2, and (2 r,3 r)-5,7,4'-trihydroxy-6-(alpha,alpha-dimethylallyl)dihydroflavonol 3, together with three known flavonoids ( 4 - 6), were isolated from the aerial parts of pterocaulon alopecuroides. the structures of the compounds were determined by mass and by 1 d and 2 d nmr spectroscopy. screening of the a ...200818704884
proteus rebound: reconsidering the "torture of nature".though carolyn merchant has agreed that francis bacon did not advocate the "torture of nature," she still maintains that "the very essence of the experimental method arose out of human torture transferred onto nature." her arguments do not address serious problems of logic, context, and contrary evidence. her particular insistence on the influence of the torture of witches ignores bacon's skepticism about witchcraft as superstitious or imaginary. nor do the writings of his successors sustain her ...200818702399
antibacterial properties of fish mucus from channa punctatus and cirrhinus mrigala.extracts and preparations made from the animal origin were used extensively in folk and modern medicine for treating many human diseases. in the present study efforts have been made to find the antimicrobial effect of the mucus of two bottom dwelling fresh water fishes namely, channa punctatus and cirrhinus mrigala. fish mucus were tested against ten pathogenic bacteria such as escherichia coli, klebsiella oxytoca, klebsiella pneumoniae, lactobacillus vulgaris, proteus mirabilis, pseudomonas aer ...200818700685
skin and soft tissue infection: frequency of aerobic bacterial isolates and their antimicrobial susceptibility pattern. 200818700650
confirmation of presumptive salmonella colonies contaminated with proteus swarming using the polymerase chain reaction (pcr) method.in mexico, zero tolerance regulation is practiced regarding salmonella in food products. the presence of which is verified by the procedure described in nom 114-ssa-1994. during the period between august 2002 and march 2003, 245 food samples were tested using this procedure in the central laboratories of the department of health for the state of jalisco (ceeslab). of these 245 samples, 35 showed presumptive colonies contaminated with proteus swarm cells even after selective isolation. these swar ...200718693548
antibacterial iridoid glucosides from eremostachys laciniata.eremostachys laciniata (l) bunge (family: lamiaceae alt. labiatae; subfamily: lamioideae) is one of the 15 endemic iranian herbs of the genus eremostachys. a decoction of the roots and flowers of e. laciniata has traditionally been taken orally for the treatment of allergies, headache and liver diseases. three antibacterial iridoid glucosides, phloyoside i (1), phlomiol (2) and pulchelloside i (3) have been isolated from the rhizomes of this plant. the structures of these compounds were elucidat ...200918693303
dna fragmentation in microorganisms assessed in situ.chromosomal dna fragmentation may be a direct or indirect outcome of cell death. unlike dna fragmentation in higher eukaryotic cells, dna fragmentation in microorganisms is rarely studied. we report an adaptation of a diffusion-based assay, developed as a kit, which allows for simple and rapid discrimination of bacteria with fragmented dna. intact cells were embedded in an agarose microgel on a slide, incubated in a lysis buffer to partially remove the cell walls, membranes, and proteins, and th ...200818689511
[current issues related to nosocomial infections in general surgery].the authors analyze the prevalence of nosocomial infections in their facility between 1999 and 2006. the annual rates ranged from 1.92 % to 4.24 %, with an average prevalence of 3.12 %. the most frequent were wound infections, febrile conditions associated with positive blood culture and urinary tract infections. in nosocomial infections, the average length of hospitalization increased by a factor of 3.5 and treatment costs rose. sporadically, multiresistant strains were detected, such as mrsa, ...200818688770
the pathological newborn in small animals: the neonate is not a small adult.the rate of perinatal death is variable but highest during parturition, immediately after birth and in the first days of life. infectious diseases, above all bacterial, are the second most important cause of mortality after losses during parturition. a lot of factors are involved predisposing puppies and kittens to bacterial infections: respiratory distress, hypothermia, hypoglycaemia, dehydration, congenital abnormalities. e. coli, streptococci and staphylococci, klebsiella sp., pseudomonas sp. ...200818688749
[intestinal enterobacteria of the hibernating apis mellifera mellifera l. bees].dynamics of enterobacteria of normal intestinal microflora was studied in apis mellifera mellifera l. bees hibernating under snow in the western urals. the cell numbers (n) of the predominant species klebsiella oxytoca increased from 10-10(6) cfu/bee in november 2004 to 10(4)-10(7) cfu/bee in march 2005; its frequency of occurrence (p) increased from 92 to 100%. increase of providencia rettgeri (11.2004: n up to 10(6), p 25%; 03.2005: n 10(2)-10(6), p 80%) was accompanied by the substitution of ...200818683661
proteus syndrome complicated by multiple spinal meningiomas.proteus syndrome is a complex and highly variable disorder comprising malformations and overgrowth of multiple tissues. we present a 65-year-old japanese man who had multiple spinal meningiomas and accompanying neural symptoms. his right leg showed hypertrophy with cerebriform connective-tissue naevus on the sole, and macrodactyly. chest computed tomography imaging revealed mild cystic and emphysematous lung changes, which were possibly related to proteus syndrome. otherwise, he had no particula ...200818681877
tigecycline: a critical update.tigecycline is the first food and drug administration (fda) approved glycylcycline antibiotic. it has shown remarkable in vitro activity against a wide variety of gram-positive, gram-negative and anaerobic bacteria including many multidrug resistant (mdr) strains. however, it has minimal activity against pseudomonas aeruginosa and proteus spp. to date, little resistance to tigecycline has been reported. clinical trials studying complicated skin and skin-structure infections (csssis) demonstrated ...200818676218
effects of proteus mirabilis lipopolysaccharides with different o-polysaccharide structures on the plasma membrane of human erythrocytes.the effects of o33 and o49 p. mirabilis lipopolysaccharides (lpss) on human erythrocyte membrane properties were examined. physical parameters of the plasma membrane, such as membrane lipid fluidity, physical state of membrane proteins, and osmotic fragility, were determined. the fluidity of the lipids was estimated using three spin-labeled stearic acids of doxyl derivatives: 5-doxylstearic acid, 12-doxylstearic acid, and 16-doxylstearic acid. all the applied labels locate to different depths of ...200818669036
structure and serological properties of the o-antigen of two clinical proteus mirabilis strains classified into a new proteus o77 serogroup.two proteus mirabilis strains, 3 b-m and 3 b-k, were isolated from urine and faeces of a hospitalized patient from lodz, poland. it was suggested that one strain originated from the other, and the presence of the bacilli in the patient's urinary tract was most probably a consequence of autoinfection. the o-polysaccharide was obtained by mild acid degradation of the lipopolysaccharide of p. mirabilis 3 b-m and studied by sugar analysis and nuclear magnetic resonance spectroscopy, including two-di ...200818665848
approach in an adolescent proteus male patient with megafoot.proteus syndrome is a rare overgrowth syndrome characterized by hemihypertrophy, lower limb asymmetry, hyperpigmentations, lipomas, and vascular malformation. in this paper, we present a new adolescent proteus syndrome patient with bilateral megafoot. he was very successful in playing football and was very popular among his friends. we present this case for the psychological and surgical aspects of this very interesting entity. we also review the recent literature related with proteus syndrome.200818664091
biodegradation of reactive blue 59 by isolated bacterial consortium pmb11.morphologically different, three bacterial strains, capable of decolorizing reactive blue 59 were isolated from dye effluent contaminated soil sample, collected from ichalkaranji, india. the individual bacterial strains viz. bacillus odysseyi suk3, morganella morganii suk5 and proteus sp. suk7 decolorized reactive blue 59 (50 mg l(-1)) completely within 60, 30, 24 h, respectively, while the bacterial consortium pmb11 of these strains required 3 h for the complete decolorization. the decolorizati ...200818661161
pyelo-hepatic fistula.a 43-year-old woman with hypertension presented to the emergency department with oliguria, fever, and abdominal pain. physical examination and laboratory evaluation revealed sepsis and acute renal failure. blood culture yielded proteus mirabilis. imaging studies showed markedly enlarged right kidney with abscess communicating with liver. to our knowledge, this is the first report of pyelo-hepatic fistula.200818649927
multiple feather follicle cysts in a moroseta hen (gallus gallus).an 8-month-old white feathered, black skinned moroseta hen was presented for examination because of numerous 2 mm- to 30 mm-diameter irregularly shaped, hard nodules in the skin of the head, wings, back, and abdomen. the nodules were confined to the skin and did not involve subcutaneous tissues. nodules consisted of dilated feather follicles packed with a caseous tan-to-pale-yellow material admixed with feather remnants. histologically, affected feather follicles were markedly dilated and filled ...200818646468
bacterial flora of captive houbara (chlamydotis undulata), kori (ardeotis kori) and rufous-crested (eupodotis ruficrista) bustards.a survey was carried out to investigate the aerobic bacterial flora of captive houbara (chlamydotis undulata), kori (ardeotis kori) and rufous-crested (eupodotis ruficrista) bustards maintained at the national avian research center, abu dhabi, united arab emirates. none of the houbara or rufous-crested bustards sampled were bred in captivity by the center but four of the kori bustards sampled were captive-bred. faecal, cloacal, oropharyngeal and skin samples (from under the wing) from clinically ...199618645872
health studies on the indian house crow (corvus splendens).fifteen indian house crows (corvus splendens) were obtained from a live-trap in dar es salaam, tanzania. two died soon after arrival. the remainder were examined clinically prior to euthanasia. all birds were examined post-mortem and a limited number of laboratory investigations was performed. none of the birds showed significant clinical signs or pathological lesions. lice were found on one. only escherichia coli and proteus spp. were isolated from the rectum. coccidia were detected in three bi ...199618645865
[investigation on species composition of cockroaches and bacteria-carrying on their bodies in five cities of hainan]."za-type" cages were used to capture cockroaches in 267 sites of 5 cities in hainan. species were identified and bacteria were isolated by routine method. 441 cockroaches were collected and identified as five species belonging to two genera, 75.3% being periplaneta americana. more cockroaches were found in sewerage. bacteria were detected from 82.4% of cockroaches, including escherichia coli, pseudomonas aeruginosa, salmonella sp, staphylococcus aureus, shigella sp, bacillus proteus and sort of ...200818637594
detection of kpc-2 in a clinical isolate of proteus mirabilis and first reported description of carbapenemase resistance caused by a kpc beta-lactamase in p. mirabilis.an isolate of proteus mirabilis recovered from blood cultures of a diabetic patient was shown to be resistant to imipenem, meropenem, and ertapenem by disk diffusion susceptibility testing. amplification of whole-cell and/or plasmid dna recovered from the isolate with primers specific for the bla(kpc) carbapenemase gene produced an amplicon of the expected size which was confirmed to be bla(kpc-2) by sequence analysis. transformation of a susceptible escherichia coli host with plasmid preparatio ...200818632900
repression of motility during fimbrial expression: identification of 14 mrpj gene paralogues in proteus mirabilis.proteus mirabilis alternates between motile and adherent forms. mrpj, a transcriptional regulator previously reported to repress motility, is encoded at the 3' end of the mrp fimbrial operon in p. mirabilis. sequencing of the p. mirabilis genome revealed 14 additional paralogues of mrpj, 10 of which are associated with fimbrial operons. twelve of these genes, when overexpressed, repressed motility; several distinct patterns of swarming motility were noted. expression of 10 of the 14 mrpj paralog ...200818630347
quantification of proteus mirabilis virulence factors and modulation by acylated homoserine lactones.measurement of the main proteus mirabilis virulence factors would increase our understanding of how the organism infects and colonizes the urinary tract. the purpose of this study was to quantify the virulence factors of twelve p. mirabilis laboratory strains and to determine whether expression of virulence factors of p. mirabilis depends on the presence of homoserine-lactone derivatives.200818629420
the lon protease regulates swarming motility and virulence gene expression in proteus mirabilis.a mini-tn5lacz1 transposon insertion in a gene encoding an orthologue of the lon protease conferred a hyper-swarming phenotype on proteus mirabilis. the lon mutation increased the accumulation of mrna for representative class 1 (flhdc), class 2 (flia) and class 3 (flaa) genes during swarmer cell differentiation. in addition, the stability of the flhd protein was fourfold higher in the lon : mini-tn5lacz1 background. expression of a single-copy lon : lacz fusion increased during the swarming cycl ...200818628491
monozygotic twins discordant for proteus syndrome.proteus syndrome is a rare, complex disorder predominantly characterized by asymmetric overgrowth of body parts, connective tissue and epidermal nevi, and vascular malformations. general diagnostic criteria comprise mosaic distribution, sporadic occurrence, and progressive course. we report on proteus syndrome in discordant monozygotic twins. the affected 9-year-old boy showed progressive postnatal overgrowth of his right leg and foot and asymmetric progressive overgrowth of single toes with a s ...200818627057
hemihypertrophy in a neonate. 200818626110
outer membrane antigens of the uropathogen proteus mirabilis recognized by the humoral response during experimental murine urinary tract infection.proteus mirabilis, a gram-negative bacterium, is a frequent cause of complicated urinary tract infections in those with functional or anatomical abnormalities or those subject to long-term catheterization. to systematically identify surface-exposed antigens as potential vaccine candidates, proteins in the outer membrane fraction of bacteria were separated by two-dimensional gel electrophoresis and subjected to western blotting with sera from mice experimentally infected with p. mirabilis. protei ...200818625734
serotyping of clinical isolates belonging to proteus mirabilis serogroup o36 and structural elucidation of the o36-antigen polysaccharide.the o-specific polysaccharide (ops) isolated from the lipopolysaccharide of proteus mirabilis o36 was found to have a pentasaccharide repeating unit of the following structure: -->2)-beta-d-ribf-(1-->4)-beta-d-galp-(1-->4)-alpha-d-glcpnac6ac-(1-->4)-beta-d-galp-(1-->3)-alpha-d-glcpnac-(1-->. the structure is unique among proteus ops, which is in agreement with the classification of this strain into a separate proteus o-serogroup. remarkably, the p. mirabilis o36-polysaccharide has the same struc ...200818625011
proteus' syndrome as a differential diagnosis of vascular malformations. 200818622970
genetic determinants of self identity and social recognition in bacteria.the bacterium proteus mirabilis is capable of movement on solid surfaces by a type of motility called swarming. boundaries form between swarming colonies of different p. mirabilis strains but not between colonies of a single strain. a fundamental requirement for boundary formation is the ability to discriminate between self and nonself. we have isolated mutants that form boundaries with their parent. the mutations map within a six-gene locus that we term ids for identification of self. five of t ...200818621670
synthesis of some novel imidazole-based dicationic carbazolophanes as potential antibacterials.synthesis of fluorescent imidazole-based dicationic carbazolophanes incorporating various spacer units is described. interestingly, the cyclophanes 2a and 5a incorporating a pyridine moiety exhibited superior antibacterial activity against most of the pathogenic bacteria in the tested concentrations as compared to the other cyclophanes as well as the test control, benzalkonium chloride (bac), cetylpyridinium chloride (cpc) and tetracycline.200818620857
antimicrobial activity and durability of a novel antimicrobial-impregnated bladder catheter.the main objective of this study was to examine the antimicrobial activity and durability of a novel indwelling bladder catheter impregnated with minocycline and rifampin. thirty antimicrobial-impregnated bladder catheters were inserted transurethrally in spinal cord-injured patients and removed, in six groups of five catheters each, at 3, 7, 10, 14, 17 or 21 days. removed catheters had detectable zones of inhibition against two different clinical isolates of each of the 10 tested uropathogens ( ...199718611809
susceptibility of pseudomonas aeruginosa to a photodynamic effect of the arginine hematoporphyrin derivative.the photodynamic effect of the arginine hematoporphyrin derivative (hpd-arg(2)) on the growth of selected pseudomonas aeruginosa clinical isolates is described as compared to the effect of hematoporphyrin derivative (hpd). growth inhibition of hpd-arg(2) of three gram-positive strains (staphylococcus aureus, bacillus subtilis and micrococcus luteus) and five laboratory strains of gram-negative bacteria (escherichia coli, proteus vulgaris, p. aeruginosa, klebsiella pneumoniae and enterobacter clo ...199718611781
comparative in vitro activity of l-ofloxacin and fk037 to other agents against 10,040 fresh clinical isolates.fresh clinical isolates collected from november 1, 1992 through november 1, 1993, were tested by agar dilution against 26 different antimicrobial agents including fk037 and l-ofloxacin. among the 10 040 organisms tested were staphylococcus aureus (n = 1222), methicillin-resistant staphylococcus aureus (mrsa, n = 455), staphylococcus epidermidis (n = 533), staphylococcus hominis (n = 90), staphylococcus hemolyticus (n = 89), streptococcus pneumoniae (n = 144), escherichia coli (n = 2326), klebsie ...199618611710
clinical efficacy and safety of cefetamet pivoxil in toddlers.the safety and efficacy of cefetamet pivoxil, an oral cephalosporin of the third generation, have been studied in open, prospective, randomized comparative, clinical trials including 301 toddlers (children aged 1 to 2 years) with upper and lower respiratory tract infections, and urinary tract infections. cefetamet pivoxil (cat) syrup formulation was given to 177 toddlers either in the standard dose of 10 mg/kg b.i.d. [n = 116] or 20 mg/kg b.i.d. [n = 61] and 124 toddlers have been treated with c ...199418611612
cefuroxime axetil.cefuroxime is the first commercially-available second-generation cephalosporine to be widely used in therapy; it is a semi-synthetic cephalosporin obtained from the 7-cephalosporanic acid nucleus of cephalosporin c. cefuroxime axetil is the acetoxyethyl ester of cefuroxime. the majority of micro-organisms associated with respiratory infections are highly sensitive to cefuroxime. these include haemophilus influenzae, streptococcus pneumoniae, streptococcus pyogenes and the other streptococci (exc ...199418611587
cefetamet pivoxil: a review of its microbiology, toxicology, pharmacokinetics and clinical efficacy.cefetamet pivoxil is an oral, third-generation cephalosporin whose broad spectrum of antibacterial activity and favorable pharmacokinetic profile make it particularly suitable for the treatment of a wide range of infectious diseases. cefetamet has high in vitro activity against both gram-positive and gram-negative bacteria that cause a number of respiratory tract and urinary tract infections. these include penicillin-sensitive streptococcus pneumoniae, streptococcus spp, haemophilus influenzae, ...199218611503
asymptomatic bacteriuria in the elderly: high prevalence and high turnover of strains.asymptomatic bacteriuria (asb) was followed in repeated prevalence surveys in a cohort of non-institutionalized residents (n=330), aged>or=80 y. urine samples were collected at baseline, and at 6, and at 18 months. phenotyping (pheneplate) was performed on isolates of escherichia coli to evaluate strain relatedness. asb occurred in 19.0, 19.4, and 19.9% in women, and in 9.4, 9.6 and 7.9% in men, at baseline and at the 6- and 18-months follow-up, respectively, and asb was found at least once in 3 ...200818609196
synthesis and antimicrobial studies of novel 1-benzhydryl-piperazine sulfonamide and carboxamide derivatives.a series of novel substituted 1-benzhydryl-piperazine sulfonamide 8(a-f) and benzamides 9(a-h) were synthesized and their antimicrobial activities evaluated in vitro by paper disc diffusion and micro dilution method against standard strains of gram-positive (staphylococcus aureus atcc 25953, staphylococcus epidermis 25212, bacillus cereus 11778, bacillus substilis 6051) and gram-negative (escherichia coli atcc 25922, pseudomonas aeruginosa atcc 2853, proteus vulgaris atcc 2853 and salmonella typ ...200818608768
cricothyroidotomy vs. sternal tracheotomy for challenging airway anatomy.although tracheotomies are the standard procedure for elective surgical airways, some patients present with challenging anatomy. in circumstances of abnormal skeletal deformities, such as kyphoscoliosis, the airway is also often tortuous and access to the trachea may be difficult. in the situation of severely distorted tracheal anatomy, where access to the trachea may require a mediansternotomy, a cricothyroidotomy may be the safer option. this article details the technique involved in approachi ...200818607301
surface acoustic wave biosensor as a tool to study the interaction of antimicrobial peptides with phospholipid and lipopolysaccharide model membranes.surface acoustic wave biosensors are a powerful tool for the study of biomolecular interactions. the modulation of a surface-confined acoustic wave is utilized here for the analysis of surface binding. phase and amplitude of the wave correspond roughly to mass loading and viscoelastic properties of the surface, respectively. we established a procedure to reconstitute phospholipid and lipopolysaccharide bilayers on the surface of a modified gold sensor chip to study the mode of action of membrane ...200818605705
common pathogens isolated in diabetic foot infection in bir hospital.foot ulcers are a frequent complication of patients suffering with diabetes mellitus, accounting for up to 20% of diabetes-related hospital admission . secondary infection of these ulcers is by far the leading cause of amputation of feet and legs and the polymicrobial nature of diabetic foot infection has been well documented in the literature. the present study sought to reveal the bacterial etiology of diabetic foot ulcer in patients presenting to bir hospital.200618603922
the mtor pathway and its role in human genetic diseases.the signalling components upstream and downstream of the protein kinase mammalian target of rapamycin (mtor) are frequently altered in a wide variety of human diseases. upstream of mtor key signalling molecules are the small gtpase ras, the lipid kinase pi3k, the akt kinase, and the gtpase rheb, which are known to be deregulated in many human cancers. mutations in the mtor pathway component genes tsc1, tsc2, lkb1, pten, vhl, nf1 and pkd1 trigger the development of the syndromes tuberous sclerosi ...200818598780
[etiology of acute and chronic pyelonephritis in children in khabarovsk region].microflora of urinary tract was studied in 419 children aged 1 - 17 years and hospitalized due to acute or chronic pyelonephritis. etiology of inflammatory process was established in 57.8% of cases. according to our study, etiologic structure of causative agents of pyelonephritis did not differ from all-russian data. the leading positions belonged to gram-negative microorganisms from enterobacteriaceae family: escherichia coli, proteus mirabilis, and klebsiella spp. results of the study point to ...200818595469
[evaluation of the phoenix automated microbiology system for detecting extended-spectrum beta-lactamase in escherichia coli, klebsiella species and proteus mirabilis].the aim of this study was to compare the bd phoenix (beckton dickinson diagnostic systems, usa) extended-spectrum beta-lactamase (esbl) test with the clinical and laboratory standards institute (clsi) esbl phenotypic confirmatory test by disk diffusion (clsi esbl test) in escherichia coli, klebsiella pneumoniae, klebsiella oxytoca and proteus mirabilis.200818594169
flavonols and an oxychromonol from piliostigma reticulatum.the leaf extract from the plant piliostigma reticulatum was found to exhibit antimicrobial activity against some bacteria and fungi such as staphylococcus aureus (nctc 6571), escherichia coli (nctc 10418), bacillus subtilis (nctc 8236), proteus vulgaris (nctc 4175), aspergillus niger (atcc 10578) and candida albicans (atcc 10231). upon investigation of the chemical constituents present in the leaf extract, a total of seven compounds were isolated and their structures were unambiguously establish ...200818582911
tapering immunosuppressive therapy significantly improves in vivo cutaneous delayed type hypersensitivity responses.immunosuppressive therapy affects cell-mediated immunity and thereby increases the frequency of infections and malignancies in transplanted patients. we questioned whether reducing the immunosuppressive dose in stable kidney transplant patients has an in vivo effect on cutaneous delayed type hypersensitivity responses (dth) reflecting cell-mediated immunity. we measured dth responses to recall antigens (tetanus, diphteria, streptococcus, tuberculin, candida, trychophyton, proteus, glycerin contr ...200818573662
antibacterial and preliminary phytochemical and physico-chemical analysis of eucalyptus citriodora hk leaf.the present communication deals with some studies on the antibacterial, physico-chemical and phytochemical parameters of different extracts of eucalyptus citriodora leaf. the antibacterial study was performed using the agar ditch method on some clinically important bacteria, namely pseudomonas pseudoalcaligenes, proteus vulgaris, citrobacter freundii, staphylococcus subflava, bacillus megaterium, and enterobacter aerogenes. physico-chemical parameters namely water, methanol, 1,4-dioxane, dmf, ac ...200818569717
biofilm structure differentiation based on multi-resolution analysis.quantitative parameters for describing the morphology of biofilms are crucial towards establishing the influence of growing conditions on biofilm structure. parameters used in earlier studies generally fail to differentiate complex three-dimensional structures. this article presents a novel approach of defining a parameter vector based on the energy signature of multi-resolution analysis, which was applied to differentiating biofilm structures from confocal laser scanning microscopy (clsm) biofi ...200818568669
urease-positive bacteria in the stomach induce a false-positive reaction in a urea breath test for diagnosis of helicobacter pylori infection.this study investigated the influence of urease-positive non-helicobacter pylori bacteria on the results of a urea breath test (ubt) to evaluate the diagnostic utility of a ubt using film-coated [(13)c]urea tablets. the ubt was performed in 102 patients treated with a proton pump inhibitor and antibiotics for the eradication of h. pylori. urease-producing bacteria other than h. pylori were isolated and identified from the oral cavity and stomach. in 4/102 patients, the ubt gave false-positive re ...200818566138
bacteriology of wound infections in the surgical wards of a teaching hospital in enugu, nigeria.during a 24-month period, january 2001 - december 2002, 404 wound swabs from 390 patients made up of 280 from surgical wounds, 92 from ulcers and 32 from other wounds like lacerations and discharging sinuses were studied. the prevalence of bacterial organisms and their antibiotic susceptibility pattern was analyzed, using standard bacteriologic techniques. two hundred and sixty four organisms (69.8%) were isolated from surgical wounds, 82 (21.7%) from ulcers and 32 (8.5%) from other wounds. coli ...200718564650
optimal probe length and target location for electrochemical detection of selected uropathogens at ambient temperature.we have previously demonstrated the clinical validity of the rapid detection of uropathogens by use of a dna biosensor. this assay involves the hybridization of capture and detector probe pairs with bacterial 16s rrna target molecules to form a dna-rna sandwich on the sensor surface. horseradish peroxidase-conjugated antibody binds to the detector probe to enzymatically amplify the hybridization signal. these previous studies involved the hybridization of bacterial 16s rrna target sequences with ...200818562584
the kinetics of growth of proteus vulgaris in nicotinic acid-limited cultures.proteus vulgaris is shown to take up nicotinic acid in the early stage of growth in amounts greater than needed for growth. the time variation of the specific nicotinic acid content of the cells, calculated by dividing the amount of nicotinic acid taken up from the liquid medium by the mass of cells present at that time, is interpreted to define two parameters, the maximum specific nicotinic acid content, f(1), and the minimum content required for growth, f(2) the difference, e, between these pa ...198718561122
depolymerization of chondroitin c sulfate by immobilized proteus vulgaris cells.chondroitinase abc catalyzing the depolymerization of chondroitin sulfate was induced by incubating the proteus vulgaris cells in a medium containing chondroitin c sulfate as an inducer. incubation of p. vulgaris cells for 12 h in the presence of 0.3% inducer was optimal to obtain the cells with highly active chondroitinase abc. such cells were immobilized in k-carrageenan gel lattice, and some properties of chondroitinase abc in immobilized cells were studied in comparison with those of the enz ...198618555284
afebrile emphysematous pyelonephritis. 200818550410
observations on the development of the crystalline bacterial biofilms that encrust and block foley catheters.the care of many patients undergoing long-term bladder catheterisation is complicated when the flow of urine through the catheter is blocked by encrustation. the problem results from infection by urease-producing bacteria, especially proteus mirabilis, and the subsequent formation of crystalline biofilms on the catheter. the aim of this study was to discover how p. mirabilis initiates the development of these crystalline biofilms. the early stages in the formation of the biofilms were observed o ...200818550219
contemporary management of uncomplicated urinary tract infections.uncomplicated urinary tract infections (uutis) are common in adult women across the entire age spectrum, with mean annual incidences of approximately 15% and 10% in those aged 15-39 and 40-79 years, respectively. by definition, utis in males or pregnant females and those associated with risk factors known to increase the risk of infection or treatment failure (e.g. acquisition in a hospital setting, presence of an indwelling urinary catheter, urinary tract instrumentation/interventions, diabetes ...200818547131
detection of a lysozyme inhibitor in proteus mirabilis by a new reverse zymogram method.a reverse zymogram method for the detection of bacterial lysozyme inhibitors was developed. this method was validated by using a periplasmic protein extract of escherichia coli containing a known inhibitor and subsequently led to the detection of a new proteinaceous hen egg white lysozyme inhibitor in proteus mirabilis.200818539812
[in-vitro activity of panipenem against clinical isolates in 2006].the antimicrobial activity of various antibiotics against clinical bacterial isolates recovered from patients with infectious diseases at the medical facilities in the kanto region between march and september 2006 was evaluated. a total of 1030 clinical isolates were available for susceptibility tests: 420 aerobic gram-positive organisms, 520 aerobic gram-negative organisms, 30 anaerobic gram-positive organisms and 60 anaerobic gram-negative pathogens. antimicrobial susceptibility data for strep ...200818536215
[influence of the mixed inoculum on the species-identification and antimicrobial susceptibility test results by the automated microbial systems].the influence of the mixed inoculum on the species-identification and antimicrobial susceptibility test results was evaluated for the three automated microbial systems, walkaway-40 (dade microscan, west sacramento, ca, usa), vitek 2 compact (biomérieux, marcy l'etoile, france) and raisus (nissui pharmaceutical, tokyo). in the evaluation, two different species or two different strains were mixed in serial ratios and adjusted to the inoculum cell suspension for the respective systems, and then tes ...200818516962
tigecycline in the treatment of complicated intra-abdominal and complicated skin and skin structure infections.tigecycline, a glycylcycline related to the tetracycline class of antibiotics, represents a new option for the treatment of complicated intra-abdominal and complicated skin and skin structure infections. it displays favorable activity in vitro against the most common causative gram-positive, gram-negative and anaerobic pathogens. in addition, tigecycline demonstrates activity against drug-resistant pathogens such as methicillin-resistant staphylococcus aureus, vancomycin-resistant enterococci, a ...200718516315
surveillance study in europe and brazil on clinical aspects and antimicrobial resistance epidemiology in females with cystitis (aresc): implications for empiric therapy.uncomplicated cystitis in females is among the most frequent infections in community.200818511178
real-time pcrs and fingerprinting assays for the detection and characterization of salmonella genomic island-1 encoding multidrug resistance: application to 445 european isolates of salmonella, escherichia coli, shigella, and proteus.salmonella genomic island-1 (sgi-1) harbors a cluster of genes encoding multidrug resistance (mdr). sgi-1 is horizontally transmissible and is therefore of significant public health concern. this study presents two novel realtime pcrs detecting three sgi-1 protein-coding genes and a sgi-1 fingerprinting assay. these assays were applied to 445 european enterobacterial isolates. results from real-time pcrs were comparable to those obtained from gelbased pcrs used for the detection of sgi-1, but we ...200818500919
evolution of bacterial susceptibility pattern of escherichia coli in uncomplicated urinary tract infections in a country with high antibiotic consumption: a comparison of two surveys with a 10 year interval.for the empirical treatment of cystitis, clinicians are often guided by susceptibility data taken from urinary samples that sent to regional microbiological laboratories, which are not representatives for uncomplicated urinary tract infections (utis). to offer adequate recommendations, the distribution and susceptibility pattern of uropathogens in uncomplicated utis in women were compared with those obtained 10 years ago in our uropathogen surveillance in a primary healthcare setting.200818499768
enterobacteriaceae and related organisms isolated from shell eggs collected during commercial processing.in the united states, commercial shell eggs are washed and graded before retail. since passage of the egg products inspection act in 1971, processing guidelines have been set to ensure that external and internal characteristics are maintained. however, less is known about how commercial processing affects the safety of shell eggs. to identify enteric bacteria entering plants and persisting throughout processing, eggs were collected from 3 us commercial shell egg-processing plants on 3 separate v ...200818493013
henoch-schönlein purpura associated with proteus mirabilis urinary tract infection. 200818489061
dissemination of the ctx-m-25 family beta-lactamases among klebsiella pneumoniae, escherichia coli and enterobacter cloacae and identification of the novel enzyme ctx-m-41 in proteus mirabilis in israel.the ctx-m-25 family of beta-lactamases is a closely related family of enzymes found rarely in the world. we aimed to describe the occurrence and to understand the dissemination of this extended-spectrum beta-lactamase family among enterobacteriaceae strains in our hospital.200818487232
first prize: novel uropathogen-resistant coatings inspired by marine mussels.success in the prevention of urinary device infections has been elusive, largely due to multiple bacterial attachment strategies and the development of urinary conditioning films. we investigated a novel anti-fouling coating consisting of mussel adhesive protein mimics conjugated to polyethylene glycol (mpeg-dopa(3)) for its potential to resist conditioning film formation and uropathogen attachment in human urine.200818484883
developmental intestinal aerobic microflora in the kori bustard (ardeotis kori).a study was carried out to investigate the normal aerobic bacterial flora of developing kori bustard (ardeotis kori) chicks, captive bred at the national avian research center, abu dhabi, united arab emirates. faecal samples were collected from 14 birds at different ages from the first day of hatching until 99 days old and were cultured for aerobic bacteria. several bacterial species were isolated from the cultures, they included escherichia coli, streptococcus viridians, enterococcus faecalis, ...199818484014
proteus2: a web server for comprehensive protein structure prediction and structure-based annotation.proteus2 is a web server designed to support comprehensive protein structure prediction and structure-based annotation. proteus2 accepts either single sequences (for directed studies) or multiple sequences (for whole proteome annotation) and predicts the secondary and, if possible, tertiary structure of the query protein(s). unlike most other tools or servers, proteus2 bundles signal peptide identification, transmembrane helix prediction, transmembrane beta-strand prediction, secondary structure ...200818483082
ulcer infection by esbetal-producing proteus mirabilis: a case report.in this article, a case of decubitus ulcer infection caused by an extended-spectrum beta-lactamase-producing proteus mirabilis strain, successfully treated with oral amoxicillin-clavulanate (1-month therapy) is described. this article focuses on diffusion and clinical effect of extended-spectrum beta-lactamases-producing proteus mirabilis on treatment of gram negative lower extremity infections.200818483010
Refresh
firstprev
...11121314151617181920...
nextlast
Displaying items 1001 - 1100 of 15180