Publications

estimating va/q distributions from inert gas data with an enforced smoothing algorithm.	the accuracy of a noniterative smoothing algorithm without a nonnegativity constraint for estimating continuous va/q distributions from inert gas retentions was evaluated. simulated retention measurements computed from three assumed distributions were processed by the algorithm. original and recovered distributions were compared with the root-mean-square (rms) difference. with noise-free retentions, the rms differences were minimum with zeta = 0 (no smoothing). with simulated 3% noise, the minim ...	1986	203558
histochemical distribution of phosphatases in different regions of the epididymis of the adult rhesus monkey macaca mulatta.		1977	203524
nucleotide sequence of the dna replication origin for human papovavirus bkv: sequence and structural homology with sv40.	dna and rna sequencing techniques were used to obtain the sequence surrounding the origin of dna replication for human papovavirus bkv. the structure is characterized by a true palindrome of 17 residues followed by two sets of symmetrical sequences and a stretch of 20 at residues. within the two symmetrical sequences is a segment containing a strong purine bias, 23 of 26 nucleotides. these structures are similar, if not identical, to those found in the region of the sv40 replication, origin. wit ...	1978	203403
hormonal interactions in regulation of androgen secretion.		2000	203346
[mechanism of action of cyclic amp-dependent histone kinase. substrate specificity of the catalytic enzyme unit].	interaction of several nucleotide derivates with homogenous catalytic subunit of cyclo-amp-dependent histone kinase from pig brain is studied. inhibition constants of these compounds are calculated, and the affinity of inhibitors to the enzyme active site is evaluated. the nature of heterocyclic base is found to be the main contribution into binding with substrate. the enzyme specificity with respect to a number of bivalent metal ions is studied, and mg2+ is demonstrated to be the only efficient ...	1978	203340
theoretical considerations of local neuron circuits and their triadic synaptic arrangements (tsa) in subcortical sensory nuclei.	certain sequential models of the so-called synaptic triadic arrangements (tsa) occurring in sensory nuclei are analyzed. the considerations are addressed mainly to the lateral geniculate body. the model is based on the assumption that the neurons establishing these triads consist of conditionally coupled decision-making subunits. it might be concluded that this and similar arrangements could play a role in the discrimination between stationary and moving retinal inputs and in the detection of te ...	1988	202723
appearance of early and late components of epstein-barr virus-associated membrane antigen in daudi cells superinfected with p3hr-1 virus.	this study investigated the synthesis of membrane antigen (ma) as well as virus capsid antigen (vca) and early antigen (ea) in daudi cells which had been superinfected with the p3hr-1 strain of epstein-barr virus (ebv) and then treated with trypsin to remove initially absorbed ma-positive material from the cell surface. synthesis of ma, vca and ea was completely inhibited by puromycin. a marked reduction in the frequency of ma positive cells was observed in superinfected cells cultured in the pr ...	1978	202665
ionic mechanism for the generation of horizontal cell potentials in isolated axolotl retina.	the ionic mechanism of horizontal cell potentials was investigated in the isolated retina of the axolotl ambystoma mexicanum. the membrane potentials of both receptors and horizontal cells were recorded intracellularly while the ionic composition of the medium flowing over the receptor side of the retina was changed. the membrane potential of the horizontal cell is highly depender side of the retina was changed. the membrane potential of the horizontal cell is highly dependent on the extracellul ...	1988	202664
neurophysiology of pain.		1988	202520
relationship between the reduction of oxygen, artificial acceptors and cytochrome p-450 by nadph--cytochrome c reductase.	the interaction of nadph--cytochrome c reductase with oxygen, artificial acceptors and cytochrome p-450 was studied. the generation of superoxide anion radicals (o2-.) from the oxidation of adrenaline to adrenochrome catalysed by nadph--cytochrome c reductase proceeds independently of the interaction of the enzyme with the artificial anaerobic acceptors cytochrome c or 2,6-dichlorophenol-indophenol. propyl 3,4,5-trihydroxybenzoate inhibited competitively the adrenaline oxidation by isolated nadp ...	1977	202259
characteristics of energy metabolism in specialized muscle of bovine heart.	characterization of the energy metabolism pattern of the specialized heart muscle of bovine heart was studied in comparison with that of the ordinary heart muscle. mitochondrial oxygen consumption of the specialized heart muscle was significantly lower than that of the ordinary heart muscle with succinate as the substrate. on the other hand, there was no significant difference in oxygen consumption between both heart muscles with glutamate + malate as the substrates. the activity levels of succi ...	1976	201990
[learning by doing].		1994	201872
comparison of plasma immunoreactive and bioactive corticotrophin [proceedings].		1994	201713
prolyl hydroxylase in the skin of patients with obstructive jaundice.	prolyl hydroxylase was estimated in the skin of 24 jaundiced patients and 25 non-jaundiced patients. the activity of this enzyme was markedly reduced in the skin of the jaundiced patients.	1994	201671
[enzymes of the pentose phosphate pathway in the brains of rats during long-term deprivation of the paradoxical stage of sleep].	the selective paradoxical sleep (ps) deprivation in rats entailed during first 2 days a drop in activity of glucose-6-phosphatehydrogenase by 80 and 60%, and of 6-phosphogluconatdehydrogenase -- by 20--35 and 40--50% in the brain-stem and the cortex, respectively. activity of the transketolase decreased by 27--29% on the 2nd day of ps deprivation only. on the 4th day, normalizing of activity of all the enzymes under study except transketolase, was observed in both regions of the brain. the consu ...	1977	201508
effect of combined dopaminergic and gaba-ergic stimulation on ouabain-induced epileptiform activity.	in this study we tested a hypothesis that dopamine and gaba receptor-stimulating agents given together might mutually potentiate their anticonvulsant activities. to test this hypothesis, experiments were performed on free-moving rabbits with epileptiform activity evoked by cortical application of ouabain. after combined treatment with apomorphine and ghba 3 out of 6 animals displayed no eeg epileptiform activity, and in the remaining 3 rabbits this activity was greatly reduced. a combined pretre ...	1977	201458
comparison of the binding characteristics of bovine thyrotropin and human chorionic gonadotropin to thyroid plasma membranes.		1977	201451
emc viral infection of the coronary blood vessels in newborn mice: viral vasculitis.	the coronary arteries, veins and capillaries of newborn mice experimentally infected with encephalomyocarditis (emc) virus were studied histologically and electronmicroscopically. damage to these coronary vessels was patchy. some lesions were extensive, particularly when adjacent to areas of myocardial damage. the histological findings consisted of swelling of adventitial and endothelial cells pyknosis, and polymorphonuclear leucocyte and round cell infiltration. histological and ultrastructural ...	1977	201264
the equilibrium constant and the reversibility of the reaction catalysed by nicotinamide-adenine dinucleotide kinase from pigeon liver.	the reversibility of the nad+ kinase reaction was established, and the kinetic parameters of the rate equation in the reverse direction were determined. the equilibrium constant of the reaction was determined by using the purified pigeon liver enzyme and radioactively labelled nicotinamide nucleotides. the relationship between kinetic parameters of the forward and reverse reactions is in reasonable agreement with the measured equilibrium constant. as expected from the proposed mechanism of actio ...	2003	201249
polymyxin b and rifampin: new regimen for multiresistant serratia marcescens infections.	polymyxin b and rifampin were given to 12 patients with multi-drug-resistant nosocomial serratia marcescens infections. eight cures were achieved; drug hepatotoxicity occurred once; one fatal suprainfection was encountered; and two patients died during therapy of causes related to severe underlying illnesses. polymyxin b and rifampin were uniformly synergistic in vitro against the infecting strains and against 40 additional clinical isolates of s. marcescens.	1977	201214
blood chemistry and lipid profiles of elite distance runners.	in summary, we conclude that the analysis of the blood profiles of elite runners offers no explanation for their superior fitness of physical ability when compared to the good runners. selected enzymes related to cellular or tissue damage may be elevated in distance runners and could be classified as abnormal on routine clinical evaluation if unaware of their physical lifestyles. it is also important to note that certain blood profile parameters, especially the hematocrit, could be classified as ...	2003	201207
corticosteroid-responsive skeletal muscle disease associated with partial carnitine deficiency: studies of liver and metabolic alterations.	a patient with progressive skeletal muscle weakness had lipid-containing vacuoles in type i muscle fibers and partial carnitine deficiency of skeletal muscle. results of certain liver function tests were abnormal, marked morphologic abnormalities of liver were detected, and a reduced cyclic adenosine 3',5'-monophosphate response to glucagon was present. after the oral administration of prednisone the patient exhibited gradual but striking clinical improvement, skeletal muscle fiber vacuoles coul ...	2003	201171
the role and control of brain 5-hydroxytryptamine.		1977	201156
epstein-barr virus and cytomegalovirus antibodies in infectious mononucleosis.	a method has been evolved for the demonstration of epstein-barr virus (ebv) and cytomegalovirus (cmv) infection in 83 cases of infectious mononucleosis. serum samples were tested for ebv igm, anti-vca igg, anti-ebna, cmv igm and cmv igg antibodies. an acute-phase sample (or samples) and a convalescence sample were examined in each case, and in 44 cases an additional samples was examined 5-12 months after the illness. since the different antibodies showed characteristic differences in both titre ...	1977	201153
electron microscopic studies on the effect of acth and flavin adenine dinucleotide on adrenocortical atrophy of hypophysectomized rat.	electron microscopic observation was made on the outer fasciculata cells in the adrenal cortex of hypophysectomized rats receiving 10 mg of fad and/or 0.3 mg of acth intraperitoneally once a day for 5 consecutive days from 24 hours after hypophysectomy. the simultaneous administration of fad and acth to the hypophysectomized rat was more effective for preventing adrenocortical atrophy induced than the administration of acth alone. this effect appeared as clear cells with low electron density. wh ...	1977	201150
[the influence of dietary protein quality on the activities of several metallo-enzymes].		1977	201126
isolation of the major glycoprotein (gp 70) of simian sarcoma virus (ssv-1/ssav-1) in preparative quantities.		1977	201120
[hospitalization of the elderly].		2003	201113
[effectiveness of the use of diphenin in insuloma].		2003	201043
[specific endonuclease of klebsiella pneumoniae oks].		1977	199404
transcription of sv 40 nucleoprotein complexes in vitro.		2001	199173
[serum lipids in experimental atherosclerosis in guinea pigs treated with protein hydrolysate].	the authors carried out studies on 223 male guinea pigs, weighting from 350 to 500 gm, fed with a diet containing 0,3% of cholesterol, disolved in cow butter. a part of the animals were injected with protein hydrolysate every other day for a period of 140 days. the level of serum lipids-total cholesterol, beta-lipoproteins, phospholipids and total lipids was examined. they found significantly higher values in the animals, receiving cholesterol in comparison with the control animals-292.4:84.9; 1 ...	1977	196824
[diurnal rhythm of cell proliferation at the late stages of precancerous changes in the liver induced by ortho-aminoazo-toluene].	orthoaminoazotoluol was administered to mice for a period of nine months. circadian rhythms of mitotic activity and the number of the dna-synthesizing cells were determined by autoradiography (with the use of 3h-thymidine) at the second (adenomatous nodes) and the third (primary hepatoma) stages of carcinogenesis in the developing tumours and the surrounding liver parenchyma. the listed structures proved to have a single-peak rhythm of mitotic activity with the maximum of mitoses at 4-7 a. m.; t ...	1994	196705
some less familiar roentgen manifestations of carcinoma of the lung.		1994	196347
retention deficit for avoidance training in hypophysectomized rats: time-dependent enhancement of retention performance with post-training acth injections.		1977	195888
a comparative ultrastructural and biochemical study between the effects of chlorphentermine and phentermine on rat lung.		1977	195833
enzymes of the purine ribonucleotide cycle in rat hepatomas and kidney tumors.		1977	195718
the effects of l9394 on adrenergic transmission in the cat spleen [proceedings].		1977	195662
bacteriology of the human biliary tract and the duodenum.	using the modern anaerobic transport media and meticulous culture techniques, 74 patients undergoing biliary tract surgery were studied. the biliary system was found to be sterile in 58 patients (78%). fifteen patients had 35 isolates of aerobic and facultative bacteria. the most common ones were klebsiella, enterococcus, and escherichia coli. the only anaerobe isolated was clostridium perfringens. eight of 17 patients (47%) with acute cholecystitis and five of 49 patients (10%) with chronic cho ...	1977	195558
radiation effects on testes. xi. studies on glycogen and its metabolizing enzymes following radiation-induced atrophy.		1977	195299
[acupuncture for pains of the face and the head is there any reasonable application? (author's transl)].	the physiological bases of the treatment with acupuncture as well as its practical application in pain therapy were discussed at the meeting of the orl-society of munich on the 4th december, 1976.	1977	195167
[studies on the antimicrobial effect of vitamin d (author's transl)].	in in vitro studies vitamin d3 proved inhibitory on strains of staphylococcus aureus, streptococcus pyogenes, klebsiella pneumoniae. escherichia coli, and candida albicans. in the presence of 5x10(4)-9x10(4) iu/ml vitamin d3 the organisms were killed or reacted with a marked growth inhibition.	1977	195120
splenic influence of t cell function: the immunobiology of the inbred hereditarily asplenic mouse.		1977	194980
polybrominated biphenyls in raw milk and processed dairy products.	milk from four dairy herds identified by the michigan department of agriculture as containing less than .3 ppm (fat basis) physiologically incorporated polybrominated biphenyls was processed individually into cream, skim milk, butter, and stirred curd cheese. pasteurized and freeze-dried whole milk, skim milk, and cream, spray-dried whole milk and skim milk, and condensed whole milk were made also. polybrominated biphenyls were concentrated in the high-fat products. pasteurized skim milk, butter ...	2003	193876
the storage lipids in tangier disease. a physical chemical study.	the physical states and phase behavior of the lipids of the spleen, liver, and splenic artery from a 38-yr-old man with tangier disease were studied. many intracellular lipid droplets in the smectic liquid crystalline state were identified by polarizing microscopy in macrophages in both the spleen and liver, but not in the splenic artery. the droplets within individual cells melted sharply over a narrow temperature range, indicating a uniform lipid composition of the droplets of each cell. howev ...	1977	193870
effects of chaotropic agents versus detergents on dihydroorotate dehydrogenase.	as chaotropic salts are generally believed to affect water structure in a manner which increases lipophilicity of water, they may seem to be capable of substituting for detergents in the solubilization of particulate enzyme. although solubilization either by detergents or by chaotropic salts has been demonstrated with several membrane proteins, the effects these agents have on the properties and activity of an enzyme may be quite different. this is illustrated by the effects on mammalian mitocho ...	1977	193834
histopathological changes in mice treated with extracts of the histamine-sensitizing factor of bordetella pertussis.	the histamine-sensitizing factor (hsf) of bordetella pertussis was isolated in a highly purified form. in addition to inducing profound sensitization to histamine, it also caused a significant lymphocytosis and produced an enhancement of reaginic antibody production in animals upon immunization with antigen. biologically active doses of hsf produced significant pathological changes in mice including congestion and edema of the lung and a marked depletion of cells in the thymus, white pulp of the ...	1977	193800
affinity of sendai virus for the inner ear of mice.	the direct immunofluorescent antibody method revealed that sendai virus, which was thought to be most prevalent in respiratory diseases in mice, infected the inner ear of mice when the virus was injected intracerebrally. specific immunofluorescence that indicated the presence of antigens of sendai virus was observed in both perilymphatic and endolymphatic structures. the routes of virus spread are discussed. this experimental study, using newborn mice and sendai virus, may be useful for the inve ...	1977	193797
human nasal epithelial cell culture system: evaluation of response to human interferons.	this report describes the response of human nasal epithelial cells to exogenously applied human interferon (if). to measure the response, a system developed to study human nasal epithelial cells in vitro was used. nasal epithelial cells responded equally to both leukocyte and fibroblast if, with development of resistance to virus replication that was time and dose dependent. cells required contact with 1,000 u of if (400 69/19 reference units) for 4 h to produce consistently a significant reduct ...	1977	193789
polymyxins as inhibitors of polyclonal b-cell activators in murine lymphocyte cultures.	the polymyxin antibiotics polymyxin b sulfate and colistin methane sulfonate were examined for their ability to inhibit responses to the polyclonal b-cell activators (pba) bacterial lipopolysaccharide (lps), dextran sulfate (ds), pneumococcal polysaccharide (siii), and purified protein derivative of tuberculin (ppd) in spleen cell cultures. polymyxin concentrations of 1 and 10 microng/ml significantly inhibited both the deoxyribonucleic acid synthetic and polyclonal antibody responses stimulated ...	2003	193787
effect of storage, different media constituents and dilution of axenic medium on the growth of axenic culture of entamoeba histolytica.		1977	193783
cell surface markers on epithelial-burkitt hybrid cells superinfected with epstein-barr virus.	attempts were made to superinfect two epithelial-burkitt hybrid cell lines, designated d98/hr-1 and d98/raji, with epstein-barr virus (ebv) and to investigate the expression of some cell surfacr markers including histocompatibility antigens, and the presence of b-cell markers, such as receptors for the third complement component and for monkey red blood cells. successful superinfection of d98/hr-1 cells with ebv was made evident by the expression of early antigen and, to a lesser extent, virus c ...	1977	193641
failure to find beta-adrenergic receptor binding in guinea pig cerebral cortex with [3h]dihydroalprenolol.		1977	193615
[etiology of acute respiratory infection in hospitalized children (author's transl)].	incidence of respiratory tract infection represents 23% of the total number of admissions between 1-24 months of age, during a period of 18 months. the diagnosis were: bronchiolities, 143 cases; bronchopneumonia, 134 cases; tracheobronchitis, 50 cases; laryngitis, four cases, and bacterial pneumonia, 61 cases. monthly incidence was maximal in december of each year. from the total group, 144 cases were included in the present study to determine etiology of the infection. in 19% of the cases a ser ...	1976	193420
integration and regulation of mitochondrial assembly in yeast.	the interactions between the mitochondrial and nucleocytoplasmic systems required for mitochondriogenesis have been investigated at several different levels. those involved in the formation of functional enzyme complexes have been studied using cytochrome oxidase: this multimeric (2 x 7 and 2 x 6 subunits for enzymes from yeast and beef heart respectively) has been resolved, and the mitochondrial contribution has been shown to be dispensible for catalytic function proper. using novel mutants, wi ...	1977	192997
[bacteriological studies on mecillinam (author's transl)].		1977	192923
expression of klebsiella nif and his genes in salmonella typhimurium.	derivatives of salmonella typhimurium carrying f prime or p prime plasmids with klebsiella nif and his genes had specific nitrogenase activities similar to klebsiella in selective conditions, even to showing "hyperinduction" under argon. no evidence was obtained for catabolite repression of normal nif expression but dibutyl cyclic amp often augmented "hyperinduction". in non-selective conditions the klebsiella his nif determinants were rapidly lost from the plasmids; the low levels of nif expres ...	1977	192833
putrescine transport is greatly increased in human fibroblasts initiated to proliferate.	putrescine (diaminobutane) was previously found to stimulate proliferation of human fibroblasts in tissue culture, and a growth factor produced by these cells was identified as putrescine. in the present paper putrescine transport is studied. the rate of putrescine transport was dependent on temperature, and most of the labeled putrescine was retained by the cells after washing with excess unlabeled putrescine. the concentration of radioactivity after a [14 c]putrescine pulse was 85 times higher ...	1976	192729
effects of prostaglandin on substrate uptake and cell division in human diploid fibroblasts.	pg (prostaglandin) e1 inhibits the uptake of iridine, thymidine, 2-deoxy-d-glucose and l-isoleucine into human diploid wi38 fibroblasts. the inhibition occurs within seconds of the addition of the prostaglandin to the culture. pge2, pgf1alpha and pgf2alpha behave similarly. arachidonic acid and 8,11,14-eicosatrienoic acid also decrease uptake in the presence or absence of indomethacin. other unsaturated fatty acids such as oleic acid, linoleic acid and linolenic acid are essentially inactive. ri ...	1977	192204
factors affecting the binding of [3h]adenosine 3':5'-cyclic monophosphate to protein kinase from bovine adrenal cortex.	inorganic salts, several proteins and traces of protein precipitants were tested to find out by what mechanisms they modulate the binding of cyclic [3h]amp to protein kinase (atp-protein phosphotransferase; ec 2.7.1.37). the separation of free and bound cyclic amp by (nh4)2so4 precipitation was unaffected by the above agents and was more reliable than the millipore filtration technique. several binding sites for cyclic amp were revealed in adrenal-cortex extract. when this extract was used as bi ...	1977	192203
effect of adrenocorticotrophic hormone on muscle acetylcholinesterase and nonspecific esterase.	acetylcholinesterases in the muscle homogenates of hamsters receiving acth intraperitoneally for six weeks were reduced as compared to the activities in the control samples. in polyacrylamide disc gel electrophoresis of the acth-treated muscles some acetylcholinesterase bands were absent. these observations may be significant in explaining the acth-induced improvement in myasthenia gravis patients and in the pathophysiology of steroid myopathy.	1992	192033
postmenopausal osteoporosis: the effect of parathormone and large dose vitamin d3 on the serum calcium level in sex hormone deficient rats.	rats deprived of adrenal and gonadel sex hormones are more sensitive than normal rats to the hypercalcaemic (osteolytic) effect of parathormone and toxic doses of vitamin d3. it is suggested that sex hormone deficiency and the consecutive decrease of calcitonin sensitivity in postmenopausal osteoporosis makes the patients unprotected against factors inducing increased bone resorption, and this leads over the years of osteoporosis.	1975	192029
rat adrenocortical dynamics.	1. the dynamics of the adrenocortical response to adrenocorticotrophic hormone (acth) was studied in anaesthetized, acutely hypophysectomized male rats. 2. acth test-signals were applied either in a jugular vein ('intact infused preparation') or in the aorta through the coeliac artery with the aorta ligated below this artery ('isolated in situ perfused preparation'). the adrenocortical responses were measured directly in samples serially taken from the left adrenal vein. 3. tested acth signals w ...	1977	191596
[microbial resistance to formaldehyde. i. comparative quantitative studies in some selected species of vegetative bacteria, bacterial spores, fungi, bacteriophages and viruses].	the resistence of different microorganisms to formaldehyde was determined. as test objects served gram-negative and gram-positive vegetative germs (klebsiella pneumoniae, pseudomonas aeruginosa, salmonella paratyphi-b, staphylococcus aureus, streptococcus faecalis), bacterial spores (bacillus cereus, bacillus pumilus, bacillus stearothermophilus, bacillus subtilis), fungi (aspergillus niger, candida albicans), bacteriophages (escherichia coli phages, t1, t2, t3), and viruses (adenovirus, poliomy ...	1976	190825
[glomus tumors in unusual sites].	two cases of glomus tumour in unusual sites are described. their indistinct symptomatology, site and histological polymorphism are made the basis of a general discussion of the histogenesis and possible ongoing pictures of glomus tumours, the classification of which is also felt to be unsatisfactory.	1992	190559
cholecalciferol metabolites binding in porcine parathyroid glands.	we studied the cytoplasmic and nuclear binding of 25-hydroxychole-calciferol and 1alpha,25-dihydroxycholecalciferol inside porcine parathyroid glands. both sterols bind to cytoplasmic components, but a specific nuclear uptake was demonstrated only for 1alpha,25-dihydroxycholecalciferol. these findings support the hypothesis that mammalian parathyroid glands are a target organ for some cholecalciferol metabolites.	1976	189464
acth and brain rna: changes in content and labelling of rna in rat brain stem.	the influence of synthetic acth1-24 and acth1-10 on rat brain rna was studied. acth1-24 (5 iu/100 g s.c.) treatment resulted in a small decrease in labelling of brain stem rna (-12%), measured 30 min after the injection of [5-3h] uridine (100 muci; s.c.), without affecting the distribution of radioactivity of the acid-soluble precursor pool. furthermore, a small and transitional reduction of total brain stem rna was found. similar treatment of adrenalectomized rats (36 h after surgery) resulted ...	1976	189247
inoculation experiment of marek's disease vaccine contaminated with a reticuloendotheliosis virus.	two-day-old chicks were inoculated with one or ten doses of marek's disease (md) vaccine originated from the herpesvirus of turkeys (hvt) and contaminated with a reticuloendotheliosis virus (rev). as a result, they presented such symptoms as abnormality in the vane of remiges, undergrowth, anemia, and leg paralysis. these symptoms were the same as those induced by the same vaccine among chicks in the field. control chicks which had been placed in the same house as those inoculated with the vacci ...	1976	189219
phosphorylation in membranes of intact human erythrocytes.	studies of phosphorylation in membranes of intact human erythrocytes were performed by incubating erythrocytes in inorganic [32p]phosphate. analysis of membrane proteins by polyacrylamide gel electrophoresis showed a pattern of phosphorylation similar to that observed when ghost membranes were incubated with [gamma-32p]atp. membrane lipid phosphorylation was also similar in intact cells and ghosts. the most heavily phosphorylated lipid, polyphosphoinositide, was closely associated with glycophor ...	1977	188816
[clinical picture and prognosis of insulinoma].	a case of insulinoma is reported, with initial malignant degeneration, diagnosed and operated 16 years ago. six years later hypoglycemic attacks appeared again and lymph metastasis from malignant degenerated insulinoma were found near to the pancreas. after a period of eight years, in good health state, a third surgical operation was performed because of repeated hypoglycemic attacks and a new metastasis from the insulinoma was found in the pancreas tail. the patient has no hypoglycemic phenomen ...	1994	188260
[spondylodiskitis caused by klebsiella pneumoniae, an unusual complication of diverticular sigmoditis].		1976	188196
[effects of the nervous system on the kidney. part i. review of the literature].	the authors review the literature on the effects of the nervous system on the kidney in 3 stages: 1) historical stage when the role of the renal nerve supply was overetimated by claude bernard. 2) intermediate stage between the two wars with a clinical description of uremic encephalits or acute delirium. from the experimental point of view was demonstrated the inessential character of the nerve supply for the survival of the kidney. 3) modern stage: from the clinical point of view one may distin ...	1976	188168
[mixed hyperlipoproteinemias. importance of diet].	the interest of diet is particularly clear in mixed hyperlipemia. in fact, the authors were only able to define the type of lipid abnormality after a test diet and prolonged supervision. one should never treat mixed hyperlipemia straightaway with hypocholesterolemic agents. the authors studied 22 patients with a form only demonstrable in the laboratory. there were no clinical signs of arteriosclerosis. in the group of dyslipemic subjects with minor hyperlipemia, they obtained normal figures for ...	1994	188159
[a further case of pseudotumoral softening of the brain].		1994	188143
experimental chemotherapy of schistosomiasis xii. active derivatives of aminoethanethiosulfuric acids.		1993	188114
[clinical observations on 2 cases of congenital pulmonary malformation].	the present paper reports on two cases of congenital malformation of the lungs, in young adults, treated surgically. each case had particular clinical features: left pulmonary aplasia with residual thymus and herniation of the right lung in the left pleural cavity in one case, and left pulmonary hypoplasia with aberrant pulmonary circulation, secondary cystic bronchiectasia, serofibrinous pleurisy. the necessity of an early diagnosis and surgical treatment is emphasized.	1993	188113
[reducing the risk of tuberculosis in children vaccinated with bcg].	in 1973, of 1774192 children aged 18 months to 6 years, 82,2% had to be revaccinated with bcg, 10.7% presented tuberculin reactions larger than 10 mm and 7.1% were absentees. in 1974 a number of 485 children belonging to the respective age group contracted tuberculosis. analysis of these cases showed that the risk of tuberculosis was of 10.9 per 100,000 revaccinated subjects and of 74.6 per 10,000 absentees. bcg vaccination not only lowered the risk of the disease but also reduced the risk of a ...	1976	188106
[the concept of risk in poliomyelitis (author's transl)].	in poliomyelitis the risk is of neurological accidents resulting either from the circulation of wild viruses (spontaneous risk) or from the introduction of virus-vaccine (vaccine risk). the spontaneous risk varies both according to the virus type and according to various factors which determine host resistance. well known among these are: the intrinsic characteristics of the population at a given period (genetic factors and previous experiences of this population with poliomyelitis viruses); env ...	1976	188083
[some aspects of carbohydrate-lipids metabolism abnormalities in state of hunger (author's transl)].		1993	188078
[the addition of ether to contrast medium lipiodol ultrafluid - a proven modification of lymphographic studies].		1993	188070
objective signs of inferior alveolar nerve anesthesia in exodontia.	objective determination of the adequacy of inferior alveolar nerve anesthesia is difficult. a dependable objective test based upon clinical observation of hundreds of patients during extraction of mandibular teeth, is presented. following routine inferior alveolar nerve block anesthesia, time is allowed for subjective signs of "tingling" of the lower lip. fully aware that the patient may respond to pressure in the absence of pain, the tooth to be extracted is tested. gradual pressure of increasi ...	1993	187994
enhancement of virus-induced cell fusion by phytohemagglutinin.		1976	187897
the cardiac sarcoplasmic reticulum - glycogenolytic complex, an internal beta adrenergic receptor.		2003	187884
[a person falling ill with acute leukemia; observations on the leukemia problem by a nurse].		1993	187871
an experimental animal model for the study of human scirrhous carcinoma.	scirrhous-like carcinomas were induced by the inoculation of cloned mouse mammary carcinoma cells into the cleared fat pads of balb/c mice. the inoculated cells induced palpable tumors in 100% of the animals within 60 days. the epithelial cells in vivo grew in rows and clusters and were attached by short developing desmosomes. microvilli and organelles were scarce; intracisternal type a particles were observed in all the epithelial cells. carcinoma cells invaded the dermis and muscle. the stroma ...	1976	187797
progesterone advancement of oestrogen-induced luteinizing hormone release during the mid-follicular phase in normal cyclic women.		1993	187708
evidence for an unidentified acth-induced steroid hormone causing hypertension.	the hypothesis that hyperaldosteronism is not the sole cause of hypertension in dexamethasone-suppressible hyperaldosteronsim was tested in an 18-year-old male. after six years of little or no treatment, the hypertension and mild hyperaldosteronism were promptly decreased by a small dose of dexamethasone. during dexamethasone treatment, when aldosterone secretion was suppressed to less than normal and he was normotensive, steroids were given by constant infusion in an attempt to reproduce the hy ...	1993	187612
plasma camp and renin in diabetics during insulin induced hypoglycemia.		2002	187538
[comparison between the official indirect method and the direct method of control of vaccines against sheep enterotoxemia].	the official methods of control of vaccines against sheep enterotoxemia are indirect in two ways : on the one hand they are carried out on animals for which the vaccine is not intended, and on the other hand they test only an immunological serum reaction. another method consisting of direct testing by intravenous injection of toxin has been carried out on mice previously vaccinated with different doses. it has been shown that it is possible to obtain a certain level of protection giving a good d ...	1976	187512
unusual postirradiation sarcoma of chest wall.	this paper reports a sarcoma of the chest wall following postoperative radiation therapy for breast carcinoma. a total of 9346 rads was delivered at a 2-cm tissue depth from two treatment courses separated by a five-year interval. the sarcoma appeared 16 years following the initial radiation course. the existence of two mesenchymal elements in the lesion led to the final diagnosis of malignant mesenchymoma. criteria for evaluating a possible radiation-induced malignancy are discussed.	2003	187315
transfer of parental immunity to infectious laryngotracheitis in chicks.	the transfer of parental immunity to infectious laryngotracheitis was appraised by measuring serum antibody levels in 150 chicks from the day of hatch up to five weeks. the breeder flock which had received primary vaccination at eight weeks and a booster at 20 weeks transferred high antibody levels which fell markedly within two weeks and remained constant thereafter. chicks whose parents were vaccinated at 20 weeks only, had low antibody levels throughout. these low levels, in either group of c ...	1976	187298
mechanisms and selectivity of anthracycline aminoglycosides and other intercalating agents.	many of the antiproliferative actions of daunorubicin and adriamycin are attributable to the results of their interaction with dna: single and double strand breaks and inhibition of repair and of nucleic acid synthesis. like other dna-reactive agents, high cumulative doses produce pharmacological actions and species-specific cytotoxicities in non-proliferating myocardium and nerve cells. evidence is reviewed suggesting that many, if not all, intercalating agents are membrane-reactive. thus it se ...	1975	187260
disaggregation of hydroxyapatite crystals.	a system has been developed to measure quantitatively the disaggregation of hydroxyapatite crystals. disaggregation was induced by pyrophosphate, ethane-1-hydroxy-1,1-diphosphonate, dichloromethylene diphosphonate, haparin and citrate. hyaluronic acid stimulated aggregation at low concentrations and disaggregation at high concentrations. lactate had no effect. the possible role disaggregation might play in the resorption of calcified tissues in vivo id discussed.	1975	187229
[the quantitative cytoarchitecture of morris hepatoma 66 (author's transl)].	introduction and methods: to obtain a statistic comparable picturg oncogenesis, tissue of a middle-fast growing morris-hepatoma 66 was transplanted into the femoral musculature. 35 days later the animals were killed by decapitation and hepatoma tissue was taken. the morphometric analysis based on the technique described by weibel (1969). results and discussion: in the morris-hepatoma 66 hepatocyte and nucleus show a much smaller single volume in comparison to normal liver cell. smaller is also t ...	1976	187163
isolation and characterization of a virus associated with progressive pneumonia (maedi) of sheep.	a virus with growth and morphologic characteristics of progressive pneumonia (maedi-visna) virus was isolated from the lungs of sheep with typical clinical and postmortem changes of chronic progressive pneumonia. the virus grew slowly in cultures of embryonic ovine lung cells, causing syncytial formation and degeneration. syncytia developed much slower and involved fewer cells than reported for other similar viruses isolated from sheep. as seen with the electron microscope, the virus reproduced ...	1976	187087
hormones and hormonal target cells in the testis.	studies over the last few years have greatly increased our knowledge about target cells for sex hormones and gonadotropins in the testis. a diagram illustrating our present state of knowledge is given in fig. 1. lh is the principle stimulus of testosterone secretion by the leydig cells. direct effects of estrogens and androgens on these cells might modulate the response to lh. androgens are apparently influencing the differentiation and the contractility of peritubular cells. fsh is the principl ...	1975	187086
stimulation by tsh of prostaglandin synthesis in pig thyroid.	the liberation of arachindonate in the thyroid occurs at the expense of two distinct pools of precursors. (1) the phosphatidylinositol through a process ca2+-dependent and cyclic amp-independent; and (2) the triglycerides by a cyclic amp-dependent lipase, in which the involvement of cyclic amp-dependent protein kinase has not yet been determined. the "pi pool" or "paracyclic amp pool" is mobilized very rapidly by large doses of tsh but its physiological significance can be discussed. the "trigly ...	1976	187042
dye-membrane interaction and its changes during nerve excitation.		1974	186824
serum glycerol and hepatic glycerokinase activity in the carbohydrate-sensitive bhe strain of rat.		1976	186795
cytoplasmic inclusions.		1974	186707