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syndactyly and split hand. supplement.in a series of studies of clinical and radiological features of hand anomalies, the author has recently encountered cases which may be explained by reference to the relationship between syndactyly and split hand. these cases suggested how the typical split hand is formed prenatally, and it is concluded that the typical split hand should not be classed as "arrest of development of parts" due to embryonal failures.1990213354
mapping the atp-binding site in the catalytic subunit of adenosine-3':5'-monophosphate-dependent protein kinase. spatial relationship with the atp site of the undissociated enzyme.a set of 24 atp analogs modified at various positions of the atp molecule was used for mapping the atp-binding site in the free catalytic subunit (c) of camp-dependent protein kinase (type i). ki values for these analogs (of which 23 were shown to be competitive with atp) were measured and compared with ki values previously obtained for the same set of analogs upon binding to the undissociated form of the enzyme (r2c2). it was found that modifications at the adenine part of atp bring about a con ...1990213278
immunological studies on cytochrome c oxidase: arrangements of protein subunits in the solubilized and membrane-bound enzyme.seven protein subunits of cytochrome c oxidase from bovine heart were isolated by gel filtration in the presence of sodium dodecyl sulphate (subunits i, ii and iii) and guanidine hydrochloride (subunits v, vi and vii), and ion-exchange chromatography in 6 m urea (subunit iv) after the enzyme had been dissociated in 6 m guanidine hydrochloride. when analysed by highly cross-linked sodium dodecyl sulphate/polyacrylamide gel electrophoresis in the presence of urea, the apparent molecular weights we ...1978213267
a time-resolved electron spin resonance study of the oxidation of ascorbic acid by hydroxyl radical.time-resolved electron spin resonance (esr) spectroscopy for the study of radicals produced by pulse radiolysis is illustrated by a study of the oxidation of ascorbic acid by oh radical in aqueous solution. in basic solution, the direct oxidation product, the ascorbate mono-anion radical, is formed within less than 2 mus of the radiolysis pulse. in acid solutions (ph 3(-4.5), n(2)o:saturated) three radicals are initially formed, the ascorbate mono-anion radical, an oh adduct seen also in steady- ...1990213133
[free radicals in normal and pathological conditions of the body]. 1978212725
neurotransmitter and cyclic nucleotide modulation of frog cardiac contractility. 1991212563
comparison of interferon action in interferon resistant and sensitive l1210 cells.translation inhibition, leu-trna aminoacylation and double-stranded rna and atp dependent phosphorylation were examined in interferon-treated and control cell-free lysates of leukaemic mouse l 1210 r and l 1210 s cells. no differences were observed between the respective interferon-treated and control cell-free extracts, except for the presence of an enhanced 67k dalton phosphoprotein fraction in interferon-treated l 1210 s cell-free extracts. in non-responding cell-free lysates, the lack of sti ...1978212514
experimental evolution in bacteria. 1978212253
genetic determination of the alpha-galactosidase developmental program in mice.the expression of alpha-galactosidase in liver, heart, and brain during postembryonic development has been examined in several inbred mouse strains. in most strains, the developmental patterns of alpha-galactosidase are coordinate with those of two other acid hydrolases, beta-glucuronidase and beta-galactosidase. certain inbred mouse strains, including members of the c57-c58 family, have a tissue-specific alteration in the temporal expression of alpha-galactosidase activity. this alteration show ...1975212204
correlation between articular cartilage collagenase activity and osteoarthritis.articular cartilage collagenase activity was determined for 28 sections obtained from twelve femoral heads. for each one square centimeter area, a section was graded by a histologic-histochemical grading system for the severity of the arthritis. collagenase activity was found primarily in those areas of moderately severe disease, but not in mild or end stage arthritis.1987212087
cholinergic stimulation of polyphosphoinositide metabolism in brain in vivo. 1978212082
[transmissible gastroenteritis of swine as a model for infectious diarrhea].transmissible gastro-enteritis is a virus-caused diarrhoeal disease of swine which may result in up to a total loss among newborn animals. changes are, primarily, of pathologicoanatomic nature and take place in the small intestine. the epithelium of the intestinal villi is completely destroyed, and diarrhoea is the result. deformation in blood composition is a secondary sequel. the diarrhoea proper causes dehydration and acidosis which, in conjunction with abnormal heart function due to hyperkal ...1978211981
[activity of the alternative complement pathway by various axenic strains of entamoeba histolytica].the activation of the alternative pathway of complement by axenic cultures of e. histolytica is reported. the activation is carried out in different proportions by several axenic strains, i.e., hk9:nih, hm1:imss, hm2:imss and hm3:imss; the end result consists of a destruction of the parasite as well as consumption of the serum complement. the participation of the alternative pathway was studied in the presence of egta and mg++, zymosan, heat-inactivation at 50 degree c for 20 min and immunoelect ...1978211963
the neural regulation of compensatory adrenal growth. 1977211910
adrenocorticotropin and plasma aldosterone concentration and deoxycorticosterone in man. 1977211909
discharge of efferent vagal fibers supplying gastric antrum: indirect study by nerve suture technique. 1978211860
cyclic amp and cyclic gmp accumulation by isolated hamster granulosa cells stimulated by lh and fsh.cyclic amp and cyclic gmp accumulation in hamster granulosa cells as a function of gonadotrophin dose (lh or fsh) and time (0-30 min) was determined. the pattern of acute cyclic amp accumulation was similar in lh and fsh stimulated granulosa cells, except that the cells were more sensitive to fsh than lh. there was a positive dose response relationship of cyclic amp accumulation in lh and fsh stimulated cells. lh appeared to partially inhibit fsh stimulated cyclic amp synthesis. cyclic gmp accum ...1987211776
[vaccine from cellular fragments of b. pertussis. ii. toxic properties of the vaccine]. 1978211762
[virological and pathological long term observation of pancreatitis in mice infected with coxsackie virus b3 (author's transl)]. 1978211725
[functioning tumors with special reference to ectopic hormone producing tumors (author's transl)]. 1978211547
malignant histiocytoma: case report. 1988211404
the effect of drugs which alter gaba-ergic function on cerebellar guanosine-3',5'-monophosphate content. 1978211362
palmitylcarnitine inhibition of the calcium pump in cardiac sarcoplasmic reticulum: a possible role in myocardial ischemia. 1978211361
[25th anniversary of the agnes karll nursing college]. 1988211327
[acth unresponsiveness]. 1988211287
catalase positive particles from pig lung. biochemical preparations and morphological studies.in pig lung tissue catalase positive particles (cps) are abundant especially in type ii pneumocytes and in clara cells. in both cell types they occur as circular, oval or elongated membrane profiles surrounding a moderately electron dense matrix lacking a crystalline core. in clara cells and in part of type ii pneumocytes they are located as individual particles without any evident morphological relation to other cell organelles. in part of type ii pneumocytes 5-8 particles are forming a group a ...1978211101
effect of n-(3,5-dichlorophenyl)succinimide on the histological pattern and incidence of kidney tumors induced by streptozotocin rats.the effect of the nephrotoxic substance, n-(3,5-dichlorophenyl)succinimide, on the histological pattern and incidence of kidney tumors induced by streptozotocin in rats was studied. in groups administered streptozotocin alone or in combination with nicotinamide, the histological pattern and the incidence of kidney tumors in rats were similar; renal cell tumors developed in 1 of 9 rats (11.1%) and in 2 of 17 rats (11.8%), respectively. however, post-treatment with n-(3,5-dichlorophenyl)succinimid ...1977211064
the spin-state transition of the hemochrome non-equilibrium conformation in partially reduced human methemoglobin. a pulse-radiolysis study of aqueous-methanol solutions of methemoglobin.the effect of external parameters on the relaxation process of the hemochrome-type non-equilibrium conformation in partially reduced methemoglobin has been investigated. the relaxation of the intermediate ferrous low-spin state to the high-spin equilibrium conformation of hemoglobin appears to be facilitated particularly by protons and phosphate ions. in addition to studying the spin-state transition in aquomethemoglobin we have also studied it in complexes of the heme group in methemoglobin wit ...1978211030
localization of central noradrenergic mechanisms in cardiovascular regulation in rats.1. various drugs were injected stereotactically into the brain of anaesthetized rats. 2. noradrenaline injected into the area of the nucleus of the tractus solitarius in the lower brain stem or into the far anterior hypothalamus/pre-optic region induced a fall in blood pressure and heart rate related to the administered dose. 3. when injected into the anterior hypothalamus/pre-optic region, clonidine and alpha-methylnoradrenaline induced a long-lasting decrease in blood pressure and heart rate.1975210991
electron-paramagnetic-resonance studies on nitrogenase of klebsiella pneumoniae. evidence for acetylene- and ethylene-nitrogenase transient complexes.klebsiella pneumoniae nitrogenase exhibited four new electron-paramagnetic-resonance signals during turnover at 10 degrees c, ph7.4, which were assigned to intermediates present in low concentrations in the steady state. 57fe-substituted mo--fe protein showed that they arose from fe--s clusters in the mo--fe protein of nitrogenase. the new signals are designated: ic, g values at 4.67, 3.37 and approx. 2.0; vi, g values at 2.125, 2.000 and 2.000; vii, g values at 5.7 and 5.4; viii, g values at 2. ...1978210766
[interferonogenic and antiviral activity of the double-stranded replicative form of phage f2 rna in tissue culture and on animals].biological activity of a new natural interferon inductor, the replicative rna form of phage f2 (rff2) was studied. a possibility of using rff2 for production of highly active interferon under conditions of superinduction providing an increase in the interferon yield by to 256--512 times as compared to the control samples was shown. the protective interferonogenic and antiviral effect of rff2 in mice infected with semliki forest virus (sfv) and tickborne encephalitis virus (tbev) was studied on a ...1978210710
glucagon effects on plasma cyclic amp and other reactants in normals and low insulin responders.the metabolic response to i.v. glucagon was evaluated in 11 normal individuals and 8 healthy low insulin responders. elevations of plasma cyclic amp and blood glucose were similar in both groups. accordingly, no indications were seen of differing hepatic responsiveness to glucagon. in contrast, the groups differed in the course of plasma glycerol during the test.1988210635
measuring interhemispheric transfer time in man. 1977210552
pain. 1989210421
effect of parathyroid hormone and insulin on extracellular cyclic adenosine-3',5'-monophosphate in patients with benign and malignant breast tumors.basal excretion of cyclic adenosine monophosphate (camp) and its basal level in blood plasma in breast cancer (bc) patients and those with fibroadenomatosis did not differ essentially. however, intravenous injection of parathyroid hormone (100 u) and insulin (0.08 u/kg body weight) was followed by a much less rise in urine-camp excretion and blood-camp levels in bc patients than in benign process in mammary gland. a substantial correlation between changes in plasma camp level and the degree of i ...1989210408
[causes of neoplastic disease and practical conclusions]. 1989210314
coenzyme b12-dependent diol dehydratase: regulation of apoenzyme synthesis in klebsiella pneumoniae (aerobacter aerogenes) atcc 8724.immunochemical studies demonstrated that klebsiella pneumoniae (aerobacter aerogenes) atcc 8724 produces only a single diol dehydratase whether grown on glycerol or on 1,2-propanediol. the enzyme was subject to induction by 1,2-diols and to catabolite repression reversed by cyclic amp.1978210157
adenoid cystic carcinoma of the cervix. a report of 7 cases. 1989210110
[estrogen therapy and carcinoma of the endometrium (author's transl)].the public discussion and the discussion among gynaecologists about the possible increased risk to develop carcinoma of the endometrium following post menopausal treatment with estrogens has lead to insecurity and restricted attitudes in the prescriptions of estrogens. in a statistic comparison of matched pairs of 130 cases of carcinoma of the endometrium with an equal number of selected control cases the following findings were elucidated: 1. any estrogen preparations do not increase the relati ...1989210085
firing rates and patterns of output and nonoutput cells in cortical areas 5 and 7 of cat during the sleep-waking cycle. 1978210033
the diagnostic value of lysosomal enzyme patterns in bronchial aspirates of patients with suspected bronchial carcinoma.the measurement of the activity of acid hydrolases and of alkaline phosphatase in bronchial aspirates obtained through bronchoscopic procedures from a series of 300 patients forms the basis for a screening program to diagnose bronchial malignant neoplasms more effectively. we define such a screening test as one permitting rapid measurements indicative of pathologic abnormalities and producing a preliminary diagnosis which, if in error, yields preferably a false-positive result. using this approa ...1989209950
biochemical and ultrastructural analysis of sv40 chromatin.sv40 chromatin can be isolated in two forms: at moderate ionic strength (mu = 0.1-0.3) it contains histone h1 in addition to the four nucleosomal histones and has a highly condensed appearance in the electron microscope, being composed of a few closely connected large spheres [190 a (160, 220) diameter]. at high ionic strength (mu = 0.6-0.8) or after prolonged exposure to very low ionic strengths (mu less than 0.02), the compact form unfolds and the chromatin shows a typical nucleosomal morpholo ...1989209938
the levels of the mitochondrial and microsomal cytochromes in drinkers' livers. 1989209909
studies on the metabolism of the lipoprotein lp (a) in man.lp(a) was isolated and labeled by reductive alkylation. radioactivity only entered the protein moiety of the lipoprotein. no change in the immunological or physicochemical properties of lp(a) was noted after the radiomethylation. after incubation of labeled lp(a) with whole serum for 24 h in vitro, more than 99% of the radioactivity of the incubated sample was found in lp(a). in 4 subjects lp(a) was injected intravenously. a linear decline of the specific activity of lp(a) in the serum was found ...1978209797
metabolic activation and hepatotoxicity. toxicity of bromobenzene in hepatocytes isolated from phenobarbital-and diethylmaleate-treated rats. 1978209739
epidemiological aspects of rotavirus infection in hospitalized venezuelan children with gastroenteritis.the prevalence of rotavirus infection in hospitalized venezuelan children with gastroenteritis was studied during the period november 1975 to december 1976. rotaviruses were the pathogens most frequently associated with gastroenteritis, being found in 121 of 293 (41.3%) patients and in only 3 of 66 (4.5%) controls. other viruses (adenoviruses, enteroviruses, and small icosahedrical viruses) were detected at a lower frequency both in cases and controls. rotaviruses were detected at a lower freque ...1978209696
[the appearance of pathognostic inclusion bodies in verruca vulgaris (author's transl)].pathognostic inclusion bodies develop in the nucleus. they frequently occur in the upper layers of the pathologically changed stratum spinosum. they are stained in an amphophilic or basophilic manner. their structure is a nearly homogenous, finely grained or plaquelike one. the inclusion bodies contain masses of human wart viruses in a cristalline-like arrangement or are irregularily distributed. feulgen staining is positive. different pictures of inclusion bodies are demonstrated in paraffin se ...1978209643
in vivo responses of paired giant mechanoreceptor neurons in aplysia abdominal ganglion.two neurons with cell bodies symmetrically located in the abdominal ganglion and giant axons in the left (l1) and right (r1) pleurovisceral connectives of aplysia californica were examined in vivo and in vitro. direct stimulation of r1 and l1 in the intact animal does not elicit any observable behavior, suggesting that they are neither motoneurons nor command neurons. these cells respond in vivo to sudden onset mechanical stimulation of widespread regions of the body. r1 and l1 spikes are initia ...1990209129
neoplastic transformation of hamster brain cells in vitro by polyoma virus.the transformation of cultivated hamster brain cells by polyoma virus is reported. the transformed cell line contained polyoma virus-specific nuclear, surface and transplantation antigens. subcutaneous and intracranial inoculations revealed high tumorigenicity of the cells. brain-specific s 100 protein was found in these tumors with immuno-peroxidase staining, suggesting that they were of a nervous nature. both in vivo and in vitro, the cells had glial features as studied by phase contrast, ligh ...1978208986
isolation of function human trophoblast cells and their partial characterization in primary cell culture.human trophoblast isolation and cell culture procedures were examined to identify variables that enhance secretion of chorionic gonadotropin (hcg) in primary culture. brief exposure of unminced first-trimester placental specimens to a solution of trypsin-edta-dnase, and isolation of the dispersed cells after ficoll-hypaque centrifugation yielded primary cultures that were high in hcg secretion and content of epithelial-like cells. the gradual decline in hcg level with time in monolayer culture i ...1978208965
measurement of cytochrome oxidase activity by kinetic microdensitometry using substrate gel films [proceedings]. 1978208706
[specific role of sex steroids on the pituitary level. sex steroids and anterior pituitary secretion].although sex steroids were known to play a role in the control of lh, fsh, tsh and prolactin secretion, in vivo experiments could not discriminate between hypothalamic and pituitary sites of action. in this study, the specific action of sex steroids at the anterior pituitary level could be achieved using rat adenohypophyseal cells in primary culture. while estrogens stimulated the sensitivity of the lh and fsh responses to lhrh, androgens had differential effects on the secretion of the two gona ...1978208692
purification of four pyruvate kinase isozymes of rats by affinity elution chromatography.1. purification of four isozymes of pyruvate kinase (atp:pyruvate 2-o-phosphotransferase, ec 2.7.1.40) l, m1, m2 and r was much improved to give good yields by affinity elution chromatography. the enzyme was eluted from a phosphocellulose column with 0.5 mm phosphoenolpyruvate. types l, m2 and r were stabilized with fructose 1,6-diphosphate throughout the purification procedures. 2. the isozymes were crystallized under various conditions: types l and r were readily crystallized from medium of lo ...1978208618
electron paramagnetic resonance in biochemistry. computer simulation of spectra from frozen aqueous samples.two computer programs are described; they can be used to simulate e.p.r. spectra of effective spin-1/2 systems in frozen aqueous samples. one program is written in basic and the other in fortran iv. both programs are deposited as a supplementary publication (sup 50082; 27 pages) at the british library lending division, boston spa, wetherby, west yorkshire ls23 7qb, u.k. references are given to the applications of these programs in biochemical work.1990208511
influence of preincubation on the development of the inhibition of protein synthesis in extracts from interferon-treated mouse l cells. action on trna. 1978208258
tumor imaging with x-rays using macrophage uptake of radiopaque fluorocarbon emulsions.radiopaque fluorocarbon (rfc) emulsions were prepared with small particle size and high concentration of the fluorocarbon. when rfc emulsions were injected intravenously in hamsters, rats, and mice with eight types of malignant tumors, the tumors became radiopaque, except in the mice with spontaneous teratoma of the ovaries. tumors as small as 3 to 4 mm could be defined radiographically using routine x-ray techniques. the tumors remained radiopaque for days to weeks after injection. light and el ...1978208188
[case of adenoma of vater's ampulla]. 1991207925
adenovirus-induced inhibition of cellular dnase.during the productive infection of kb cells by adenovirus type 5 (ad5), there is a progressive decrease in the level of cellular dnase activity towards single-stranded dna, in contrast to dna polymerase which remains relatively constant throughout the infection. this decrease is prevented by the inhibition of protein synthesis by cycloheximide. the inhibition of dnase activity does not occur after infection by ad5 ts125, a dna-negative mutant which fails to induce the adenovirus-specific dna bin ...1978207901
intramembrane changes occurring during maturation of herpes simplex virus type 1: freeze-fracture study.during the maturation of two strains of herpes simplex virus type 1 (vr3 and patton), intramembrane changes were detected with the freeze-fracture technique in the viral envelope and the infected cell plasma membrane, and these changes were compared with data obtained from thin sections. regardless of the strain, the inner leaflet of the viral envelope of extracellular virions was characterized by a density of intramembrane particles (imp) three times larger than the host nuclear and plasma memb ...1978207896
alkaline dnase activity in cells infected with a temperature-sensitive mutant of herpes simplex virus type 2.bhk cells infected with the temperature-sensitive mutant ts13 of herpes simplex virus type 2 at a nonpermissive temperature lack the alkaline nuclease activity, which is induced by the mutant at a permissive temperature and by wild-type virus at either temperature. for ts13, enzyme activity could be induced by a temperature shift to permissive conditions, but not in the presence of cycloheximide. after a shift from permissive to nonpermissive conditions in the presence of cycloheximide, the acti ...1978207883
further observations on metabolic responses in hamster cells: changes in udpg dehydrogenase activity. 1991207712
the isolation and characterization of the vitamin d-binding protein from rat serum. 1978207701
electron paramagnetic resonance studies on membrane-bound respiratory nitrate reductase of klebsiella aerogenes. 1978207577
a hundred years of the hepatotrophic controversy.venous blood returning from the splanchnic viscera has liver-supporting (hepatotrophic) qualities not found to the same degree in other kinds of arterial or venous blood. the effects of portal blood have been noted in animals with two livers (or a differential portal blood supply to different regions of one liver) to include hypertrophy, glycogen storage, hyperplasia, capacity for regeneration, increase of several synthetic functions, and maintenance of normal structure. the main splanchnic veno ...1977207494
[study of insulin receptors on liver and hepatoma cell plasma membranes].plasma membranes (pm) of helathy rats as well as those hepatomas and pm of tumor-bearing rats were found (radioreceptor assay) to have apparently two groups of receptors for insulin with a high and low affinity for the hormone respectively and different insulin-binding capacities. kass values of the receptors with a high affinity for insulin are drastically decreased in the pm of ascites zajdela hepatoma (azh) and of solid hepatoma 27 (sh-27) as well as in the liver of sh-27-bearing animals, but ...1978207360
plasma membrane cyclic amp-dependent protein phosphorylation system in l6 myoblasts.plasma membranes can be isolated without disruption of cells by the plasma membrane vesiculation technique (scott, r.e. (1976) science 194, 743-745). a major advantage of this technique is that it avoids contamination of plasma membranes with intracellular membrane components. using this method, we prepared plasma membranes from l6 myoblasts grown in tissue culture and studied the characteristics of the protein phosphorylation system. we found that these plasma membrane preparations contain prot ...1978207325
camp-phosphodiesterase inhibitors and tracheal smooth muscle relaxation. 1978207279
an indirect method of screening for lipid composition of serum lipoproteins. 1991207267
[intrinsic protein phosphorylation in the mitochondrial membranes of a calf brain (author's transl)]. 1976207233
ventriculography with water-soluble contrast medium in stereotactic neurosurgery. 2003207122
[embolization by femoral catheterization of tumors supplied by the external carotid artery. 40 cases].experiences from therapeutic embolization by way of superselective catheterization of the external carotid artery, in 40 cases of cranio-cerebral, maxillo-facial and cervical tumours are reported. using spongel, embolization offered definite advantages compared to simple arterial ligation: it is easily performed as a supplementary procedure to diagnostic superselective angiography; a meticulous technique will provide superselective arterial occlusion with obstruction of vessels down to the preca ...1991207091
[polyphosphoinositides and their functions in biological membranes]. 1978207036
thiazide diuretics do not potentiate camp response to parathyroid hormone.we evaluated the hypothesis that thiazide-induced hypercalcemia reflects potentiation of the camp response to parathyroid hormone (pth) consequent to inhibition of phosphodiesterase in bone and kidney. a panel of thiazide diuretics did inhibit low-km phosphodiesterase activity from bone homogenates. however, furosemide, a nonthiazide diuretic that does not promote calcium retention, was more potent a phosphodiesterase inhibitor than either chloro- or hydrochlorothiazide (ctz, hctz). thiazides di ...1978206800
effects of prostaglandin e2 and a prostaglandin endoperoxide analogue on neuroeffector transmission in the rat anococcygeus msucle.1 investigations were made into the effects of prostaglandin e(2) (pge(2)) and a prostaglandin endoperoxide analogue (upjohn compound u-46619) on the responses of the rat anococcygeus muscle to field stimulation of the intrinsic sympathetic nerves, and to exogenous noradrenaline. the effects of pge(2) on responses to stimulation of intrinsic inhibitory nerves were also studied.2 pge(2) (5.6 x 10(-8) or 2.8 x 10(-6) mol/l) decreased motor (sympathetic) responses to field stimulation at all freque ...1978206303
[recent developments in the physiology of the exocrine pancreas]. 1977206300
response to several avian respiratory viruses as affected by infectious bursal disease virus.after being inoculated with the infectious bursal disease virus (ibdv) at one day of age, specific-pathogen-free chickens were inoculated with either newcastle disease virus (ndv), infectious bronchitis virus (ibv), or infectious laryngotracheitis virus (iltv). their immunity was challenged 2-3 weeks later with homologous virus, and antibody titers were determined for iltv and ibv. several studies were made to determine the effects of ibdv on the development of persistent or chronic virus infect ...1978206256
investigation of the beta-adrenergic system in regulation of immunologic responses.the influence of pharmacologic stimulation and blocking of the beta-adrenergic system on appearance of pf and rf cells, and intralymphocytic levels of camp were investigated. stimulation of the beta-adrenergic receptor exerted an immunosuppressive effect, reflected by the numbers of pfc and rfc and raised levels of camp. inhibition of the adrenergic beta-receptor stimulated immunologic responses and lowered levels of camp in lymphocytes. confirmation of a specific adrenergic mechanism was provid ...1992206224
subcellular distribution of enzymes involved in alpha-glucan utilization in klebsiella pneumoniae. proteins of cytopasm, periplasm, cytoplasmic and outer membrane. 1978206221
mechanistic studies of polyene enhancement of interferon production by polyriboinosinic-polyribocytidylic acid.the production of interferon by polyriboinosinic-polyribocytidylic acid [poly(i) . poly(c)] and poly(i) . poly(c)-diethylaminoethyl-dextran in l929 cells was enhanced from 10 to 100 times by polyene macrolides, including amphotericin b (amb), amb methyl ester, nystatin, and filipin. amb and its water-soluble methyl ester were the most effective; retinol, a nonmacrolide polyene, was ineffective. interferon induction by newcastle disease virus was not enhanced by amb. the kinetics of interferon pr ...1978206199
insulin receptors are widely distributed in the central nervous system of the rat. 1978205798
macrophages, lymphocytes, and plasma cells in the perivascular compartment in chronic multiple sclerosis.perivascular cells in cns tissue from six multiple sclerosis (ms) patients and a patient with motor neuron disease were examined by light and electron microscopy. lymph node tissue from one ms patient was also examined. cns perivascular macrophages in both ma and motor neuron disease were found to closely resemble free macrophages elsewhere in the body except that they often contained unusually large primary lysosomes. cytoplasmic inclusions consisting of membrane-bound stacks of curved linear p ...1992205724
study of microsomal mixed function oxidative demethylation and deformylation of 4-methyl and 4-hydroxymethylene sterols. 1978205540
arginine metabolism in saccharomyces cerevisiae: subcellular localization of the enzymes.subcellular localization of enzymes of arginine metabolism in saccharomyces cerevisiae was studied by partial fractionation and stepwise homogenization of spheroplast lysates. these enzymes could clearly be divided into two groups. the first group comprised the five enzymes of the acetylated compound cycle, i.e., acetylglutamate synthase, acetylglutamate kinase, acetylglutamyl-phosphate reductase, acetylornithine aminotransferase, and acetylornithine-glutamate acetyltransferase. these enzymes we ...1978205532
assessment of endoscopically visible bronchial carcinomas. 1994205392
a comparative spectroscopic study of two non-haem iron proteins lacking labile sulphide from desulphovibrio gigas.the ultraviolet visible, and near infrared spectrum of a two-iron protein from desulphovibrio gigas, a new type of non-haem iron protein lacking labile sulphide, is compared with that of d. gigas rubredoxin. the charge transfer band maxima of rubredoxin at 495 and 565 nm are less separated in the new protein implying a higher symmetry of the two iron centres. the existence of a spin-spin interaction between the two iron centres in the new protein is suggested by the magnetic susceptibility measu ...1978205263
sonography of the common bile duct: value of the right anterior oblique view.the common hepatic and proximal common bile ducts (common duct) lie anteriorly and generally to the right of the portal vein in the porta hepatis. this constant anatomic relationship can be used to demonstrate the common duct and to differentiate it from the portal vein by gray scale ultrasonography. the patient is scanned longitudinally from the right anterior abdominal wall with the ultrasound beam directed posteromedially until two tubular structures are demonstrated in the porta hepatis. the ...1994205124
the synthesis and secretion of serum albumin in morris hepatomas 5123tc and 9121.in vivo, morris hepatomas 5123tc and 9121 do not secrete serum proteins into the bloodstream. however, they synthesize albumin, at a reduced rate, if compared with liver. the produced albumin accumulates, leading to an enlargement of the golgi apparatus and the appearance of intracellular vesicles. the proportion and the absolute amount of albumin found within the hepatoma cells is increased compared with liver. as described recently for liver in vivo and for hepatocyte suspensions, albumin is s ...1977205109
properties of epstein-barr virus transformed woolly monkey lymphoblastoid cell lines. 1978204945
recognition and destruction of target cells by tumoricidal macrophages. 1993204610
[embryology and etiology of the poland and amazone syndromes].in 1841 a. poland described a rare complex of malformations in the male, characterized a unilateral pectoral muscle defect combined with ipsilateral symbrachydaktyly. if in the female a poland syndrome is associated with ipsilateral hypo- or aplasia of the breast as a leading feature, we propose to name this entity "amazone syndrome". altogether 5 poland syndromes and 40 "amazone syndromes" were seen in our department. for the latter a morphological grading into four groups was performed for cli ...1993204553
non-hodgkin lymphomas: cell populations and functional behavior. 1977204551
comparative studies on nuclear and cytosol phosphohistone phosphatases of calf liver. 1978204526
cyclic gmp regulation and responses of polysphondylium violaceum to chemoattractants.in cells of the cellular slime mold polysphondylium violaceum an attractant, which is released during the aggregation stage, causes a transient rise of the cyclic gmp concentration. cells of this organism develop in shaken suspensions after they have finished growth. cell development is not accompanied by an increase in the edta stability of cell adhesion. both the developmental regulation and the specificity of chemotactic responses is reflected in the light scattering patterns recorded in cell ...1988204422
arenaviruses in perspective. 1978204386
oxidation of protein sulfhydryls by products of peroxidase-catalyzed oxidation of thiocyanate ion. 1978204336
[two outbreaks of "clostridium perfringens" food poisoning: epidemiological remarks (author's transl)].two outbreaks of cl. perfringens food poisoning which occurred in florence during 1976 have been described. the first one involved three hundred primary school children; processed re-heated turkey meat was thought to have been the vehicle of infection in the school meal. the clinical symptoms consisted of mild diarrhoea in all cases and the duration of the illness was about 12 hours. the possible part played by food storage temperature, post-cooking periods and food trolleys in the spread of inf ...1977204262
invertebrate systems for the study of hormonal effects on behavior. 1987204107
[on the interplay of stress and of feedback mechanism (author's transl)]. 1987204056
[does price control in the health care system lead to a dilemma in nursing? from the viewpoint of the german hospital society]. 1987203755
varicella-zoster virus vaccine. 1978203727
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