Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| mecillinam-ampicillin synergism in experimental enterobacteriaceae meningitis. | the in vitro activities of mecillinam, a new beta-amidinopenicillin, and ampicillin, alone and in combination, against an escherichia coli strain and a klebsiella pneumoniae strain were compared, and these results were correlated with their respective activities in vivo in experimental meningitis. the mecillinam-ampicillin combination was synergistic in vitro against both strains when tested by a modified checkerboard technique (bacteriostatic synergy). however when quantitative bactericidal syn ... | 1979 | 228591 |
| [angiodysplasias of the extremities in children. nosological problems]. | 1995 | 228141 | |
| validity of stature prediction near maturity. | 1995 | 228019 | |
| the nucleotide sequence and genome organization of the polyoma early region: extensive nucleotide and amino acid homology with sv40. | 1979 | 225042 | |
| detection of a precursor of bovine leukemia virus structural proteins in purified virions. | gel filtration chromatography of disrupted bovine leukemia virus (blv) resulted in the isolation of the 25,000 dalton major virion internal protein and two previously uncharacterized virion proteins of molecular weight 65,000 and 12,000 respectively. the 65,000 dalton protein does not bind to concanavalin a and its antigenicity is ether-resistant. therefore, this polypeptide is different from the previously described glycoprotein associated with blv. radiommunoprecipitation and competitive radio ... | 1978 | 224756 |
| stereospecific effects of opiate antagonists on superficial and deep nociception and on motor activity suggest involvement of endorphins on different opioid receptors. | 1979 | 222987 | |
| the ebv-carrying, beta2m/hla deficient burkitt lymphoma line daudi is sensitive to ebv-specific killer t-cells of mononucleosis patients. | the beta2-microglobulin/hla deficient burkitt lymphoma line daudi was tested for sensitivity to ebv-specific cytotoxicity mediated by natural killer (nk)-depleted t-cells from acute mononucleosis patients. while the daudi line was not as sensitive as the reference ebv-genome-positive target line, it was clearly sensitive in the majority of cases. this would speak against a major role of syngeneic restriction in this system. | 1979 | 222436 |
| hydrogenase activity in the dry state: isotope exchange and reversible oxidoreduction of cytochrome c3. | hydrogenase (hydrogen:ferricytochrome c3 oxidoreductase, ec 1.12.2.1) catalyzes three types of reactions, i.e., (1) conversion between hydrogen modifications, para-h2 and ortho-h2, (2) exchange reaction between hydrogen isotopes, and (3) reversible oxidoreduction of an electron carrier with h2 and protons. we observed that purified desulfovibrio hydrogenase in the dry state could catalyze not only the conversion and exchange reactions (yagi, t., tsuda, m., mori, y. and inokuchi, h. (1969) j. am. ... | 1979 | 222328 |
| role of albumin in hormone-stimulated lipolysis. | 1979 | 222292 | |
| [effect of potassium orotate and guanine on calcium uptake in small intestine of chickens with different amounts of vitamin d3]. | potassium orotate and guanine are established to accelerate the duodenum physiological response of chickens with experimental rachitis to administration of vitamin d3 in the in vivo experiments. they stumulate the uptake and transport of calcium, increase the content of calcium-binding protein and affect the activity of alkaline phosphatase. guanine is a more effective stimulator as compared to orotate. a rise in the calcium uptake in the duodenum of the chicken which were given guanine started ... | 1979 | 222028 |
| development and evaluation of social skills training for schizophrenic patients in remission. | investigated were measures of self-esteem, self-perceived attitudinal dimensions and locus of control to assess the effects of group social skills training for schizophrenic psychiatric inpatients. a pretest, posttest control group design was employed utilizing forty subjects currently in treatment. it was hypothesized that short-term cognitively structured group therapy would realize significant improvement in self-esteem, internal locus of control and assertive attitude change. significant mea ... | 1982 | 221655 |
| acth--a review of anatomy, physiology, and structure related to neuroendocrine effects. | 1982 | 221624 | |
| [a case of chronic thyroiditis associated with hyposecretion of adrenocorticotrophic hormone (acth), growth hormone (gh), immunoreactive insulin (iri) and aldosterone (author's transl)]. | 1982 | 221601 | |
| influence of intramuscular or intravenous injection of cholecalciferol on serum calcium, phosphorus and magnesium levels in the bovine. | 1979 | 221431 | |
| extraction of soluble antigens of epstein-barr virus, herpesvirus salmirl, and herpesvirus ateles with the use of glycine. | for extraction of soluble antigen from cells infected with epstein-barr virus, herpesvirus salmirl, and h. ateles, 0.1 m glycine (ph 9.5) was used. this method yielded increased amounts of the antigen containing much less cell debris. lymphoblastoid cells infected with epstein-barr virus could maintain up to 50% viability after the extraction procedure. these cells could be used again after an appropriate interval in culture. the usefulness of this technique is discussed. | 1979 | 220447 |
| effects of the aflatoxins on atpase activities in mouse and rat liver. | the effects of the aflatoxins on atpase activities in mouse and rat tissues were investigated in vitro. the hepatic oligomycin-sensitive (o.s.) mg++ atpase was inhibited significantly. the order of inhibition was g1 greater than b1 greater than g2 greater than b2. mouse o.s. mg++ atpase was more sensitive than the corresponding rat enzyme. the oligomycin-insensitive (o.i.) mg++ atpase activities in rat and mouse liver were not altered. although aflatoxins g1 and b1 were more potent inhibitors of ... | 1979 | 220299 |
| inhibition of rat liver glucose 6-phosphatase by n-alkylmaleimides [proceedings]. | 1979 | 220112 | |
| [indirect hemagglutination reaction in viral (transmissible) gastroenteritis in swine]. | 1979 | 219585 | |
| cytomegalovirus infection in cancer patients. | 1978 | 219406 | |
| [blood transfusion and viral diseases. recent acquisitions concerning viral hepatitis viruses, cytomegaloviruses and epstein-barr virus]. | in recent years, an increasingly clear picture has been formed of the virus-induced syndromes that may follow a blood transfusion or the use of blood derivatives. up to about 10 years ago, post-infusion infection was predominantly due to serum hepatitis. blumberg's discovery of hbsag (formerly known as australia antigen) has made it possible to check and prevent viral hepatitis, type b, and to recognise such distinct forms as the mononucleosis-like syndrome caused by cytomegalic virus, infectiou ... | 1979 | 219399 |
| the actions of hormones on adenylate cyclase systems. | the glucagon-sensitive adenylate cyclase system, viewed from the perspective of its behavior with isolated membrane preparations, displays far more complex regulatory characteristics than could have been envisioned from its behavior in the intact cell. what has emerged from our studies with isolated hepatic membranes is that glucagon can exert at least three actions which we believe are interdependent: desentization of the receptor, activation of adenylate cyclase, and promotion of adenosine inh ... | 2003 | 219357 |
| development of carcinoma of the breast at the site of an implanted pacemaker in two patients. | we report here on two female patients who had permanent pacemakers implanted in their chests and who developed carcinoma of the breast subsequently. an association is suspected between the breast cancer and the pacemaker, which is implanted in an area which borders with the mammary gland or is even right within it. this suspicion led us lately to change in female patients the site of the subcutaneous pocket for the implantation of the pacemaker to a position higher in the chest than before. more ... | 1985 | 219300 |
| a serological assay for the detection of cell surface receptors of nerve growth factor. | when single-cell suspensions prepared from embryonic day 8 (e8) chick sensory ganglia are incubated with nerve growth factor (ngf), anti-ngf antiserum, and complement, an ngf-dependent cytotoxic kill of 20 (+/- 3)% of the ganglia cells is observed. this percentage is increased by a factor of two when only the neuronal cells are tested. no kill is observed on the nonneuronal cell population representing 50% of the ganglia dissociate. when e8 sensory ganglia cells are cultured in the presence of n ... | 1985 | 219297 |
| [a trial of quantitative analysis of skeletal whole body scintigraphy in renal osteo-dystrophy (author's transl)]. | 1985 | 219280 | |
| the resistance of g mouse fibroblasts to murine leukemia virus infection. | in vitro resistance of g mouse cells was not expressed in the initial cycle of mulv infection but in the propagation of virus to the surrounding cells. | 1978 | 219276 |
| tryptic peptide analysis of gag gene proteins of endogenous mouse type c viruses. | tryptic digests of the internal proteins p30, p15, p12, and p10 of mouse xenotropic, ecotropic, and amphotropic type c viruses were subjected to cation-exchange chromatography. analysis of these maps revealed that the p30 proteins from representative isolates of all three viral subgroups were distinguishable. the p15 proteins were all unique. the p12 proteins of nzb xenotropic and wild-mouse amphotropic viruses were not identical and yielded peptide maps remarkably different from that of the eco ... | 1979 | 219210 |
| characterization of an epstein-barr virus-induced dna polymerase. | the addition of iododeoxyuridine to p3hr-i cell cultures led to a large increase in both epstein-barr virus (ebv)-induced dna polymerase activity and early antigen-positive cells. this ebv-induced dna polymerase was separated from the cellular alpha- and beta-polymerases by sequential column chromatography on sepharose 6b, deae-cellulose, and phosphocellulose, resulting in partial purification of about 320-fold. the partially purified-ebv dna polymerase could be distinguished from the cellular d ... | 1979 | 219209 |
| use of heme spin-labeling to probe heme environments of alpha and beta chains of hemoglobin. | a spin label attached to a propionic acid group of the heme has been used to probe the heme environment of the alpha and beta chains of hemoglobin in both the subunit and tetrameric forms. the electron paramagnetic resonance (epr) studies of hemoglobin hybrids in which the spin label is attached to either the alpha- or beta-heme (alpha2slbeta 2 or alpha2beta2sl) and spin-labeled isolated chains (alphasl and betasl) show that: 1) alpha- and beta-hemes have different environments in the tetrameric ... | 1985 | 218946 |
| cyclic nucleotides, cyclic nucleotide phosphodiesterase, and development in myxococcus xanthus. | exogenous cyclic nucleotide phosphodiesterase (pd) accelerated fruiting body (fb) formation and increased territory size of aggregates in myxococcus xanthus. both guanosine 3'5'-monophosphate (cgmp) and guanosine 5'-monophosphate (gmp) were antagonistic to the pd effect. adenosine 3'5'-monophosphate (camp) increases fb numbers twofold in the absence but not in the presence of pd. pd induction is not affected by methionine or isoleucine, which inhibit, or by threonine, which stimulates, fb format ... | 1978 | 218712 |
| an inherited anomaly of human eosinophils and basophils. | inclusions staining gray or blue-gray in romanowsky treated films were found in eosinophils and basophils in a family as an autosomal dominant anomaly without overt clinical effects. associated with the inclusions were distinctive crystals which were different from the crystalloids of eosinophil granules and from charcot-leyden crystals. the restriction of the anomaly to eosinophils and basophils indicates that these are related more closely to each other than to neutrophils and mast cells, and ... | 1978 | 218657 |
| [effect of radioprotectors on camp-dependent protein phosphorylation]. | the capacity of radioprotectors (serotonin, aminoethylisothiuronium) to stimulate in radioprotective doses camp-dependent protein phosphorylation of the cytozol and nuclei of the mouse liver and of the spleen cytozol was shown in vivo. radioprotectors were incapable of modulating in vitro the activity of protein kinases and the stimulating effect of camp. the data presented and previous investigations suggest that the activation of camp-dependent phosphorylation by radioprotectors was due to the ... | 1979 | 218656 |
| [effect of 6n2'o-dibutyryl adenosine-3',5'-cyclomonophosphate on the protein synthesis of the subpharyngeal ganglia complex in the mollusk, helix pomatia]. | proteins of the helix pomatia abdominal complex were separated by electrophoresis. the electrophoretic mobility of most of the proteins was rf = 0.2--0.6. the abdominal ganglion was incubated in the medium with 1 = (4.5h3)-leucine and 2.10(-6) m 6n2'o-dibutyryladenosine-3',5'-cyclomonophosphate for 3, 6 and 24 hours. it was shown that radioactivity of specific low-mol wt neuronal proteins was increased by the former, but the latter inhibited this process. | 1978 | 218655 |
| cell surface changes associated with mutation of visna virus in antibody-treated cell cultures. | 1979 | 218349 | |
| [hypoglycemia caused by a benign hepatic tumor]. | 1979 | 218331 | |
| acetylcholine concentration into voltage. receptor-mediated transduction. | 1979 | 218311 | |
| effect of intoxication of pregnant rats with trichlorphon on the activities of some brain enzymes in the progeny during postnatal development. | 1979 | 218149 | |
| impact of ct in the neurosurgical management of intracranial tumors. | a total of 103 brain tumor patients examined with ct, radionuclide brain scan, and angiography or pneumoencephalography, and all surgically verified, were studied to evaluate the impact of ct on the neurosurgical handling of brain tumors. ct alone was usually sufficient for optimal handling of astrocytoma patients, angiography in most meningioma cases, and pneumoencephalography in cases with sellar, suprasellar, and some other midline tumors. information obtained only through ct sometimes altere ... | 1979 | 218141 |
| glomus tumor of the middle ear: origin, symptomatology, and treatment. | the glomus tumor is considered to be the most common of all tumors that involve the middle ear. this report defines the glomus tumor and discusses the symptomatology of the tumor with respect to the various developmental courses it may follow. forty clinical cases of glomus tumor are reviewed, with emphasis upon the incidence of the tumor and its symptoms, including the audiological manifestations noted in this series of cases. current medical management of the glomus tumor recommends surgical r ... | 1979 | 218052 |
| comparative studies on the influence of hormones on metabolite compartmentation in isolated liver cells during gluconeogenesis from lactate. | 1978 | 217770 | |
| reconstitution of vitamin d3 25-hydroxylase activity with a cytochrome p-450 preparation from rat liver mitochondria. | 1979 | 217740 | |
| entamoeba histolytica: genetic control of susceptibility in chicken eggs. | 1979 | 217709 | |
| effect of thyrotoxicosis on gluconeogenesis from alanine in the perfused rat liver. | the influence and mechanism of action of t4 treatment on hepatic gluconeogenesis from alanine was studied in isolated rat livers. conversion of alanine into glucose was increased markedly in livers of thyrotoxic rats compared to that in normal rats. estimation of metabolic intermediates of the gluconeogenic pathway showed that t4 treatment produced forward cross-over between pyruvate and phosphoenolpyruvate, which suggests that this point is a control site. alanine transport into the liver cells ... | 1978 | 217582 |
| treatment of primary liver cancer: response to regional chemotherapy. | 1983 | 217565 | |
| role of peripheral side chains of vitamin b12 coenzymes in the reaction catalyzed by dioldehydrase. | 1979 | 217415 | |
| effect of beta-lapachone on superoxide anion and hydrogen peroxide production in trypanosoma cruzi. | addition of beta-lapachone, an o-naphthoquinone endowed with trypanocidal properties to respiring trypanosoma cruzi epimastigotes induced the release of o2- and h2o2 from the whole cells to the suspending medium. the same beta-lapachone concentration (4 micron) that released h2o2 at maximal rate completely inhibited t. cruzi growth in a liquid medium. the position isomer, alpha-lapachone, did not stimulate o2- and h2o2 release, and did not inhibit epimastigote growth. beta-lapachone was able to ... | 1978 | 217340 |
| development and regression of exercise-induced cardiac hypertrophy in rats. | adult female rats were exercised by daily swimming. all the increase in heart weight induced by the exercise occurred within 14 days and averaged 30%. the half times of the increases in heart weight and total protein content were about 4.5 days, whereas that of cytochrome c, which was used as a mitochondrial marker, was 6.5 days. the total amounts of dna and of hydroxyproline in the heart, which were used to evaluate the degree of connective tissue hyperplasia, increased only slightly (8% and 10 ... | 1979 | 217279 |
| s-iga cholera toxin and rotavirus antibody in human colostrum. | s-iga antibodies against cholera toxin and rotavirus were assayed in 43 colostral samples by means of an enzyme-linked immunosorbent assay (elisa). all specimens contained specific s-iga antibodies against both antigens. significant antibody titres to the antigens were demonstrated in almost all colostral samples. | 1979 | 217230 |
| gonadotropin receptors and regulation of steroidogenesis in the testis and ovary. | 1981 | 217174 | |
| [a simple technique to test the functional capacity of human monocytes (author's transl)]. | 1978 | 217112 | |
| [use of plastic isolators in the prevention of infection in high risk patients with hematologic diseases]. | the authors report a microbiological study of the flora of high risk adults with blood diseases isolated in hermetically sealed plastic isolater. this type of isolation is very effective in the prevention of infections due to hospital germs as such contamination occurred only twice in 292 days isolation and was found in only 0.8% on samples. the efficacy of methods of body decontamination and the incidence of infective complications in our series is also reported. | 1981 | 217093 |
| [myeloproliferative disorder and hepatocellular adenoma following androgen treatment of a patient with aplastic anemia (author's transl)]. | 1979 | 216824 | |
| bactericidal activity of a superoxide anion-generating system. a model for the polymorphonuclear leukocyte. | the acetaldehyde-xanthine oxidase system in the presence and absence of myeloperoxidase (mpo) and chloride has been employed as a model of the oxygen-dependent antimicrobial systems of the pmn. the unsupplemented xanthine oxidase system was bactericidal at relatively high acetaldehyde concentrations. the bactericidal activity was inhibited by superoxide dismutase (sod), catalase, the hydroxyl radical (oh.) scavengers, mannitol and benzoate, the singlet oxygen (1o2) quenchers, azide, histidine, a ... | 1979 | 216766 |
| coupling of glucagon receptor to adenylyl cyclase. requirement of a receptor-related guanyl nucleotide binding site for coupling of receptor to the enzyme. | effects of glucagon and guanyl nucleotides on the rat liver plasma membrane adenylyl cyclase were studied. it was established that: 1) glucagon stimulates the fully guanyl-5'-yl imidodiphosphate (gmp-p(nh)p)-activated enzyme between 20 and 70%, provided a guanyl nucleotide is present in the assay; 2) glucagon has no effect on adenylyl cyclase activity in membranes activated fully by gmp-p(nh)p and then washed free of nucleotides. it is concluded that occupancy of the guanyl nucleotide binding si ... | 1979 | 216687 |
| [abnormal lipoprotein (lp-x) in the first months of life with particular reference to obstructive jaundice]. | 1982 | 216613 | |
| trophoblast-specific beta1-glycoprotein as a marker for pregnancy and malignancies. | 1982 | 216610 | |
| carcinomas and other lesions of the liver in mice ingesting organochlorine pesticides. | carcinomas of the liver were readily induced in male and female mice given organochlorine pesticides orally. the carcinomas were predominantly hepatocellular, with a few being cholangiocellular, and varied from well differentiated to poorly differentiated to undifferentiated. they are capable of invading, metastasizing, and killing the mice. hemangiosarcomas, leimyosarcomas, and reticulum cell sarcomas were also occasionally seen in mice receiving these chemicals. hepatic vein thrombosis and hep ... | 1982 | 216523 |
| electrogenic events in the ubiquinone-cytochrome b/c2 oxidoreductase of rhodopseudomonas sphaeroides. | the reductant of ferricytochrome c2 in rhodopseudomonas sphaeroides is a component, z, which has an equilibrium oxidation-reduction reaction involving two electrons and two protons with a midpoint potential of 155 mv at ph 7. under energy coupled conditions, the reduction of ferricytochrome c2 by zh2 is obligatorily coupled to an apparently electrogenic reaction which is monitored by a red shift of the endogeneous carotenoids. both ferricytochrome c2 reduction and the associated carotenoid bands ... | 1979 | 216398 |
| search for type-c oncornavirus-related genetic information in tissues from patients with systemic lupus erythematosus. | single-stranded 3h-dna probes complementary to the rna of rauscher murine leukemia virus and of simian sarcoma virus were prepared using techniques that permitted complete transcription of the viral genome of each virus. these probes were used in dna-dna hybridization studies with the cellular dna from uncultured specimens of spleens and placentas of patients with systemic lupus erythematosus (sle). no proviral dna sequences related to these viruses were detected in these tissues. the results pr ... | 1978 | 216374 |
| effects of haemophilus influenzae vaccination on the (para-)sympathic-cyclic nucleotide-histamine axis in rats. | to determine whether haemophilus influenzae could be a factor in human atopy its effects were studied on the (para-)sympathic cyclic nucleotide-histamine axis in rats. haemophilus influenzae vaccination induced changes in the cholinergic system compatible with higher cyclic gmp levels and enhanced histamine release. the authors suggest an involvement of the cholinergic system in haemophilus influenzae vaccination effects. | 1979 | 216288 |
| [analysis of cases of primary liver carcinoma diagnosed on autopsy cases at the department of pathology, military medical academy]. | 1986 | 215971 | |
| synthesis of rabbit beta-globin in cultured monkey kidney cells following infection with a sv40 beta-globin recombinant genome. | rabbit beta-globin complementary dna (cdna) has been inserted into sv40 dna in place of the gene coding for the virus' major capsid protein, vp1. the recombinant genome, svgt5-rabetag, multiplies efficiently in cv1 monkey kidney cell cultures and is transcribed to yield cytoplasmic, polyadenylated hybrid mrnas containing the beta-globin coding sequence. cells propagating svgt5-rabetag produce substantial quantities of rabbit beta-globin polypeptide. | 1979 | 215915 |
| an ultramicrochemical assay for sphingomyelinase: rapid prenatal diagnosis of a fetus at risk for niemann-pick disease. | 1985 | 215902 | |
| molecular structure of elongated forms of electric eel acetylcholinesterase. | 1984 | 215774 | |
| evidence for the cell surface locus of presynaptic purine nucleotide receptors in the guinea-pig ileum. | 1978 | 215742 | |
| preoperative angiographic embolization for large hemorrhagic wilms' tumor. | preoperative angiographic embolization of the renal artery is a surgical adjunct not necessary for the majority of wilms' tumors. however, on the basis of early experience, we would recommend this technique for those large vascular tumors with preoperative hemorrhage in which the risk of embolization is likely to outweight the risk of intraoperative disruption and hemorrhage. | 1984 | 215737 |
| characterization of human tk- cell lines transformed to a tk+ phenotype by herpes simplex virus type 2 dna. | human tk- cells carrying the hsv-2 tk gene as a result of transformation with virus dna express a tk activity of virus origin and maintain the tk+ phenotype when grown in hat medium. under non-selective conditions, however, reversion to a tk- phenotype occurs with a significant frequency characteristic of each transformed line. once reversion has occurred the tk- phenotype appears to be stable, since only very rare instances of tk- to tk+ reversion have been observed. tk- revertants were suscept ... | 1979 | 215706 |
| penetration of cultured mouse fibroblasts (l cells) by rickettsia prowazeki. | the association of rickettsia prowazeki with l cells was examined by using a novel radioactive assay in which [alpha-(32)p]atp-labeled rickettsiae were incubated with l-cell monolayers. rickettsial association with the monolayer involved adherence and internalization steps that could be experimentally distinguished. since r. prowazeki but not l cells possess an atp-adp obligate exchange transport system, addition of excess unlabeled atp resulted in exchange of the labeled atp from external, adhe ... | 1978 | 215542 |
| [earth rays]. | 1984 | 215397 | |
| the free radical in ribonucleotide reductase from e. coli. | protein b2, one of the subunits of ribonucleotide reductase from escherichia coli, contains a stable free radical. it is characterized by a doublet e.p.r. signal centered around g = 2.0047 and a sharp peak at 410 nm in the optical spectrum. the radical has been assigned to a tyrosyl residue in the protein with its spin density delocalized over the aromatic ring. protein b2 also contains two antiferromagnetically-coupled high-spin iron(iii) atoms, which stabilize the free radical. protein b1, the ... | 1977 | 215392 |
| lactate-to-pyruvate or pyruvate-to-lactate assay for lactate dehydrogenase: a re-examination. | the pyruvate-to-lactate assay for determining lactate dehydrogenase (ec 1.1.1.27) can now yield linearity equal to or better than that obtained by the lactate-to-pyruvate assay. in addition, there are significant advantages to the pyruvate-to-lactate reaction: (a) a greater change in absorbance per unit time, which allows more accurate spectrophotometric readout; (b) lower reactant concentrations are required, which substantially reduces the cost per assay; (c) solid reagents are used to prepare ... | 1984 | 215347 |
| mapping unintegrated avian sarcoma virus dna: termini of linear dna bear 300 nucleotides present once or twice in two species of circular dna. | three major species of viral dna have been observed in cells infected by retroviruses: a linear, double-stranded copy of a subunit of viral rna; closed circular dna; and proviral dna inserted covalently into the genome of the host cell. we have studied the structures of the unintegrated forms of avian sarcoma virus (asa) dna using agarose gel electrophoresis in conjunction with restriction endonucleases and molecular hybridization techniques. the linear duplex dna is approximately the same lengt ... | 1984 | 215324 |
| ongoing activity in severed nerves: source and variation with time. | 1978 | 215270 | |
| ribonucleic acid synthesis in rat liver during fatty acid stimulated secretion of very low density lipoproteins. | production of very low density lipoproteins by the liver depends on the cellular availability of fatty acids. it is stimulated by the uptake of free fatty acids from the plasma and by increased lipogenesis and is inhibited by actinomycin d, suggesting that rna synthesis is involved in the regulation of apolipoprotein synthesis. this hypothesis has been investigated in rats in vivo and in isolated perfused livers with and without stimulation by fatty acid overload: [14c] orotate incorporation in ... | 1978 | 215235 |
| nitrogenase x: mössbauer and epr studies on reversibly oxidized mofe protein from azotobacter vinelandii op. nature of the iron centers. | under anaerobic conditions the molybdenum-iron protein (mofe protein) from azotobacter vinelandii can be reversibly oxidized with thionine. electron paramagnetic resonance studies reveal that the oxidation proceeds in two distinct phases: the mofe protein can be oxidized by four electrons without loss of the epr signal from the s = 3/2 cofactor centers. a second oxidation step, involving two electrons, leads to the disappearance of the cofactor epr signal. in order to correlate the events during ... | 1978 | 215215 |
| evidence for antiferromagnetic exchange coupling in the tetranuclear high potential iron-sulfur protein of rhodopseudomonas gelatinosa. | 1978 | 215143 | |
| activities and some properties of 5'-nucleotidase, adenosine kinase and adenosine deaminase in tissues from vertebrates and invertebrates in relation to the control of the concentration and the physiological role of adenosine. | 1. the maximal activities of 5'-nucleotidase, adenosine kinase and adenosine deaminase together with the km values for their respective substrates were measured in muscle, nervous tissue and liver from a large range of animals to provide information on the mechanism of control of adenosine concentration in the tissues. 2. detailed evidence that the methods used were optimal for the extraction and assay of these enzymes has been deposited as supplementary publication sup 50088 (16pages) at the br ... | 1984 | 215126 |
| attenuated dynamic responses of primary endings of muscle spindles: a basis for depressed tendon responses in acrylamide neuropathy. | depressed or lost tendon reflexes commonly observed in patients with peripheral neuropathies may result partly from attenuation of the dynamic discharge from the primary endings of muscle spindles. this possibility was investigated in cats with an experimental neuropathy induced with acrylamide (30 mg/kg/day intramuscularly). achilles tendon reflexes and the dynamic discharge from primary muscle spindles were evaluated after five or ten injections of acrylamide. after five injections the animals ... | 1978 | 215077 |
| [pathogenesis of brain lesions in acute viral respiratory infections (review)]. | 1978 | 214977 | |
| temperature-sensitive mutants of herpes simplex virus type 1 defective in transcriptional and post-transcriptional functions required for viral dna synthesis. | 1978 | 214940 | |
| [changes in functional state of the thyroid gland and thyrotropic activity of the pituitary gland in cushing's syndrome after unilateral adrenalectomy combined with radiation therapy]. | 1985 | 214891 | |
| nonspecific inhibitors of coronavirus oc43 haemagglutination in human sera. | antibodies against the human coronavirus oc43 in human sera were measured by haemagglutination inhibition (hi), complement fixation (cf), and radial diffusion-haemolysis in gel (hig) techniques. the apparent hi titres in a fraction of sera with no antibodies detectable by the two other methods were found to be reduced considerably after treating the sera with phospholipase c (plc). the plc treatment also reduced the apparent hi titres in some sera containing variable amounts of cf and/or hig ant ... | 1978 | 214680 |
| inhibition of the binding of low-density lipoprotein to its cell surface receptor in human fibroblasts by positively charged proteins. | a group of proteins and polyamino acids with positively charged domains were shown to inhibit the binding of 125i-ldl to its receptor on the surface of human fibroblasts. the list of inhibitory proteins included platelet factor 4 (which has a cluster of lysine residues at its carboxyl terminus), two lysine-rich histones, poly-l-lysines of chain length greater than 4, and protamine. these proteins were effective in the concentration range of 5--10 microgram/ml. two other positively charged protei ... | 1978 | 214639 |
| hepatosplenic myelosis in naturally occurring mouse hepatitis virus infection in the nude mouse. | 1978 | 214604 | |
| survey for antibodies to bovine leukemia virus in dairy and beef cattle in japan. | 1978 | 214603 | |
| formulation and evaluation of ethiodized oil emulsion for intravenous hepatography. | a study was conducted to prepare and evaluate an ethiodized oil emulsion for intravenous administration that would selectively opacify the liver. several formulations with differing globule size were prepared and compared for their in vivo activity (degree of liver opacification obtained) and stability. results of studies conducted in rabbits and monkeys revealed that the oil globules that concentrate most in liver were 2.0--3.0 micrometer in diameter. the formulation of choice was stable for 6 ... | 1979 | 214542 |
| mesoionic xanthine analogs as inhibitors of cyclic amp phosphodiesterase. | several derivatives of two mesoionic xanthine analogs, mesoionic thiazolo[3,2-alpha]pyrimidine-5,7-diones and mesoionic 1,3,4-thiadiazolo[3,2-alpha]pyrimidine-5,7-diones, were synthesized and evaluated as inhibitors of cyclic amp phosphodiesterase. a significant number of these compounds demonstrated theophylline-like activity. | 1978 | 214541 |
| co-induction of beta-galactosidase and the lactose-p-enolpyruvate phosphotransferase system in streptococcus salivarius and streptococcus mutans. | the addition of lactose, galactose, or isopropyl-beta-d-thiogalactoside (iptg) to glucose-grown cells of streptococcus salivarius 25975 resulted in the co-induction of both the lactose-p-enolpyruvate phosphotransferase system (lactose-pts) and beta-galactosidase, with the latter the predominant metabolic system. with various strains of streptococcus mutans and streptococcus sanguis 10556, on the other hand, the lactose-pts was the major metabolic pathway with beta-galactosidase induced either to ... | 1978 | 214423 |
| insulinoma: a review of five cases. | 1986 | 214412 | |
| studies on the biosynthesis of cyclitols, xxxvii. on mechanism and function of schiff's base formation as an intermediary reaction step of myo-inositol-1-phosphate synthase from rat testicles. | it could be shown that the formation of a schiff's base by myo-inositol-1-phosphate synthase of rat testicles occurs by binding the aldehyde group of the open form of its substrate, d-glucose 6-phosphate, to a lysyl residue of one or both smaller subunits of the enzyme. the participation of the schiff's base formation in the catalytic process is supported by the observations that (a) no schiff's base is formed if nad is removed from the enzyme, and (b) in the presence of nad, the dehydrogenation ... | 1978 | 214386 |
| [production and characteristics of a djzungarian hamster cell line (dx-tk-) resistant to 5-bromodeoxyuridine]. | new biochemically marked djungarian hamster cell line (dx-tk-) was established. these cells are resistant to 5-bromodeoxyuridine (25 mkg/ml) and deficient in thymidine kinase activity (tk-). due to this biochemical defect they have lost the ability to grow in hat medium. dx-tk- cells are malignant. they grow as tumours after the inoculation to newborn djungarian hamsters. tumorigenecity of dx-tk- cells was decreased as compared with the parent tk+ cell line. dx-tk- cell line is a hypodiploid cel ... | 1986 | 214372 |
| physiological response to aerosol propellants. | acute exposures to isobutane, propane, f-12, and f-11 in concentrations of 250, 500, or 1000 ppm for periods of 1 min to 8 hr did not produce any untoward physiological effects as determined by the methods employed which included serial ekg's and continuous monitoring of modified v5 by telemetry during exposure. repetitive exposures to these four propellants were also without measurable untoward physiological effect with the exception of the eight male subjects repetitively exposed to 1000 ppm, ... | 1985 | 214300 |
| cultured heart cell reaggregate model for studying cardiac toxicology. | this review represents a summary of the technique of using cultured heart cells as a model system for studying the physiology, pharmacology, biochemistry and toxicology of myocardial cells. the general techniques and types of culture preparations commonly used are given and some of the advantages and disadvantages of working with cultured heart cells are summarized. | 1985 | 214299 |
| translation of procollagen messenger rna in a cell free system derived from wheat germ: hydroxylation of prolyl residues in the product. | ribonucleic acid extracted from chick embryo calvaria directs the synthesis of a collagenous product in a cell-free system. a portion of the prolyl residues incorporated into this protein can be hydroxylated in vitro by prolyl hydroxylase as demonstrated by the release of 3h-h20 from 3h-proline and by the direct demonstration of 3h-hydroxyproline in acid hydrolysates of the product. thirty percent of potential sites become hydroxylated in the in vitro reaction using either cell-free product or a ... | 1985 | 214271 |
| application of electromyography in day-to-day clinical care. | 1985 | 214236 | |
| [chemiluminescence during oxidation of gossipol by peroxidase]. | gossipol oxidation with peroxidase accompanied by chemiluminescence is revealed. effect of some factors on chemiluminescence is investigated. peroxidase gossipol oxidation is suggested to be one of the causes of spontaneous cotton root luminescence. chemiluminescence in the system studied is inhibited by superoxide dismutase, which indicates the generation of superoxide anion radical. it is suggested that these radicals and other activated oxygen species are involved in the gossipol toxicity for ... | 1987 | 214169 |
| is drug abuse prevention neglected? nida chief counters critics. interview by margaret eastman. | 1987 | 213963 | |
| mechanism of action of amantadine on neuromuscular transmission. | 1978 | 213703 | |
| [an autopsy case of acute myeloblastic leukemia with persistent high anti ebv-antibody titer (author's transl)]. | 1978 | 213625 | |
| uses and abuses of electric convulsive shock therapy. | 1986 | 213565 | |
| amino acid sequence of a peptide containing an essential cysteine residue of escherichia coli gmp synthetase. | the amino acid sequence of a 51-residue tryptic peptide of citraconylated [1-14c]carboxamidomethyl-labeled escherichia coli gmp synthetase was determined by sequenator analyses of the intact peptide and fragments obtained by cleavage of the peptide with cyanogen bromide, trypsin, and staphylcoccus aureus strain v8 protease. the cysteine residue of this peptide fragment is essential for glutamine-dependent gmp synthesis activity and is implicated in formation of a hypothetical covalent glutamyl-e ... | 1978 | 213434 |