Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| otitis media in guinea pigs: pathology and bacteriology. | in the course of post-mortem examination of conventional random-bred and inbred (immunosuppressed) strain 2/n guineapigs kept in separate quarters, otitis media was diagnosed in 62 of 462 animals (13.4%) and 18 of 66 animals (27.3%) respectively. clinical signs of otitis media were seen in only two random-bred animals but in nearly 50% of affected inbred animals. in random-bred guineapigs, purulent, often bilateral, otitis media was associated mainly with the isolation of streptococcus zooepidem ... | 1986 | 3795863 |
| induced atrophic rhinitis in rats. | infections with bordetella bronchiseptica and pasteurella multocida were inducted in newborn specific-pathogen-free rats. turbinate atrophy was quantified by measuring the length of the osseous core of the ventral turbinates. bordetella bronchiseptica readily colonized the nasal cavity. inoculated rats developed serum agglutinating antibodies to b bronchiseptica. turbinate atrophy, correlating with a severe inflammatory reaction, was observed after dual inoculation with b bronchiseptica or after ... | 1986 | 3789506 |
| investigation into the pathogenesis of atrophic rhinitis in pigs. i. atrophic rhinitis caused by bordetella bronchiseptica and pasteurella multocida and the meaning of a thermolabile toxin of p. multocida. | in two groups of swine herds, herds with and without clinical ar the presence of atrophic rhinitis (ar) correlated with the presence of toxinogenic pasteurella multocida (pm) and not with the bordetella bronchiseptica (bb) infection. six bb- and eighteen pm-strains have been investigated for ar pathogenicity. broth cultures were injected intradermally in guinea-pigs (gpst) or intranasally in 3-week-old colostrum deprived specific pathogen free (spf) piglets. the average atrophy of the ventral co ... | 1986 | 3750802 |
| the synergistic activity of tiamulin and chlortetracycline: in-feed treatment of bacterially complicated enzootic pneumonia in fattening pigs. | the antibacterial effects of a combination of tiamulin and chlortetracycline in vitro against a number of field isolates of pasteurella multocida, haemophilus pleuropneumoniae and bordetella bronchiseptica were examined. there was a marked synergism between the two antibiotics against all eight isolates of p multocida, against seven of nine isolates of h pleuropneumoniae and against the single strain of b bronchiseptica tested. two field trials were carried out on a herd with a history of compli ... | 1986 | 3750792 |
| the characterisation of bordetella/alcaligenes-like organisms and their effects on turkey poults and chicks. | eight isolates of the bordetella or alcaligenes-like organisms associated with turkey rhino-tracheitis were examined. five of these isolates had been recovered from the united kingdom and three were foreign isolates. four of the uk isolates came from flocks with mild respiratory disease. the fifth isolate came from birds with no respiratory signs and this appears to be the first report of the recovery of bordetella/alcaligenes from apparently normal turkeys. the field isolates and type strains a ... | 1986 | 18766500 |
| identification of bordetella avium sp. nov. by the api 20 ne system. | the reactions of 47 bordetella avium strains in the api 20 ne micro-test system were compared to those of the species bordetella bronchiseptica, alcaligenes faecalis and alcaligenes denitrificans. the api 20 ne microtest system allowed separation between b. avium and the other species of gram-negative nonfermentative rods investigated. | 1986 | 18766558 |
| nucleotide sequence homology to pertussis toxin gene in bordetella bronchiseptica and bordetella parapertussis. | multiple strains of bordetella parapertussis and b. bronchiseptica were examined for the presence of nucleotide sequences which hybridized with a cloned 4.5-kilobase (kb) fragment of b. pertussis dna containing the genes responsible for pertussis toxin expression. all six b. parapertussis strains tested had nucleic acid sequences that hybridized with the cloned 4.5-kb fragment in southern blot analyses. when the b. parapertussis dna was digested with restriction endonuclease psti, the pattern of ... | 1987 | 3818081 |
| virulence factors of bordetella bronchiseptica associated with the production of infectious atrophic rhinitis and pneumonia in experimentally infected neonatal swine. | four strains of bordetella bronchiseptica (csu-p-1, 64-c-0406, 1120-a-83-013, and b205bt) with defined virulence for neonatal swine were examined, and an attempt was made to correlate the presence of certain in vitro phenotypic characteristics with the ability of a particular b. bronchiseptica strain to produce turbinate and lung lesions in piglets. all of the strains except csu-p-1 colonized the nasal passages of the pigs heavily, and strains 1120-a-83-013 and b205bt produced moderate to severe ... | 1987 | 3793231 |
| clonal diversity and host distribution in bordetella bronchiseptica. | a total of 303 isolates of bordetella bronchiseptica recovered from 11 host species were characterized by the electrophoretic mobilities of 15 metabolic enzymes, and 21 distinctive multilocus genotypes (electrophoretic types) were distinguished on the basis of allele profiles at the enzyme loci. the population structure of b. bronchiseptica is clonal, and its genetic diversity is limited in comparison with most other pathogenic bacteria, perhaps reflecting a relatively recent origin of the speci ... | 1987 | 3584070 |
| differentiation of bordetella avium and related species by cellular fatty acid analysis. | the fatty acids of 18 strains of bordetella avium, 3 strains of alcaligenes faecalis, 5 strains of bordetella bronchiseptica, and 12 strains of a b. avium-like organism were examined by gas chromatography-mass spectrometry. the presence of a significant amount of the acid 2-oh c14:0 characterized b. avium and the b. avium-like organism. b. avium and the b. avium-like organism differed in their relative concentrations of c16:1 and 3-oh c14:0 acids. b. bronchiseptica and a. faecalis were distingui ... | 1987 | 3597749 |
| airborne-induced experimental bordetella bronchiseptica pneumonia in strain 13 guineapigs. | to evaluate the efficacy of a commercial bacterial vaccine in protecting strain 13 guineapigs against fatal bordetella bronchiseptica pneumonia, it was necessary to establish the infectivity and disease pathogenesis induced by virulent organisms. when guineapigs were exposed to small-particle aerosols of varying concentrations of virulent b. bronchiseptica, a spectrum of disease was produced that ranged from inapparent illness to fulminant bronchopneumonia. clinical signs began by day 4 after ex ... | 1987 | 3626470 |
| pharmacokinetics of cefazolin in guinea pigs. | the occurrence of antibiotic-related enterocolitis in guinea pigs restricts the use of many common antibiotics in this species. cephaloridine, an antibiotic frequently recommended for this species, is no longer available and a substitute has yet to be explored. in this study, the potential therapeutic efficacy of cefazolin, also a first generation cephalosporin, was evaluated in guinea pigs by assessing pharmacokinetics, toxicity and the minimal inhibitory concentration for selected animal patho ... | 1987 | 3695403 |
| [quantitative study of the sensitivity of bordetella bronchiseptica and pasteurella multocida to sulfonamides]. | information concerning the resistance to sulfonamides in the netherlands was obtained by determining the minimal inhibitory concentrations (mic's) of 119 strains of bordetella bronchiseptica and 151 strains of pasteurella multocida, obtained from pigs at five veterinary bacteriology centres, to sulfadimidine (sdm) and sulfamethoxazole (smx). the mic's of sdm against su-susceptible strains were usually 4 times higher than those of smx. about one third of b. bronchiseptica isolates were resistant ... | 1987 | 3824346 |
| [comparative local and systemic immunization against experimentally-induced bordetella bronchiseptica pneumonia in icr mice]. | it is described the experimental bordetella bronchiseptica infection via aerosol in icr mice. 10(6) living bacteria were found in the lung after aerosol challenge with a total of 10(12) cfu. the pneumonias produced in this infection model within 10 days are focal, interstitial and proliferative to a low and medium degree, respectively. they are significantly reduced already by a single i.p. or s.c. immunization. two vaccinations with inactivated bordetellae or a temperature sensitive mutant redu ... | 1987 | 3687105 |
| efficacy of commercial vaccines for protecting guinea pigs against bordetella bronchiseptica pneumonia. | autogenous bacterins are recommended to protect guinea pigs (cavia porcellus) against pneumonia due to bordetella bronchiseptica. bordetella vaccines are available commercially for several other animal species. the substantial antigenic cross-reactivity among bordetella isolates from various animal species suggests that immunity resulting from use of these vaccines might protect guinea pigs. groups of ten individually housed hartley guinea pigs from a colony free of bordetella were vaccinated wi ... | 1987 | 3599889 |
| a rapid enzyme-linked semi-microwell assay for the enumeration of antibody-forming cells to viral and bacterial antigens in domestic animals. | details of an enzyme immunoassay for the enumeration of antibody-forming cells are given with examples of its application to immunization with viral (newcastle disease virus) or bacterial (haemophilus pleuropneumoniae) pathogens of domesticated species. the assays showed reciprocal specificity when compared to another virus (avian paramyxovirus serotype 3) or another bacterium (bordetella bronchiseptica) and were used to show the class specificity of avian afc and the effect of passive antibody ... | 1987 | 3611797 |
| isolation and characterisation of bordetella avium and related species and an evaluation of their role in respiratory disease in poultry. | a total of 24 gram negative non fermentative bacteria obtained from poultry were compared with reference strains of bordetella avium, alcaligenes faecalis, bordetella bronchiseptica and a bordetella avium-like organism. thirteen isolates were identified as b. avium and 11 were identified as b. avium-like. a commercial microidentification kit (the api2one) did not identify the field isolates but did separate them correctly into the 2 groups. a practical identification scheme, suitable for diagnos ... | 1987 | 3689262 |
| prevention of atrophic rhinitis in piglets by means of intranasal administration of a live non-ar-pathogenic bordetella bronchiseptica vaccine. | the effect of intranasal vaccination of piglets with live non-ar-pathogenic bordetella bronchiseptica (bb-) against atrophic rhinitis (ar) was investigated in a preliminary investigation and in a field trial. in the preliminary investigation 2-day-old spf piglets (n = 13) were vaccinated. three weeks after vaccination, challenges were carried out by means of a spray with an ar-pathogenic b (bb+) or an ar-pathogenic pasteurella multocida (pm+) broth-culture. four weeks later the piglets were necr ... | 1987 | 2956754 |
| evidence for sialyl glycoconjugates as receptors for bordetella bronchiseptica on swine nasal mucosa. | the nature of the receptors for bordetella bronchiseptica was investigated by using the in vitro adherence assay system. the results indicated that sialyl glycoconjugates acted as receptors on swine nasal mucosa. these results were obtained by two independent approaches: inhibition of epithelial cell adherence with sialic acid-containing compounds but not with compounds lacking sialic acid residues and loss of adherence after treatment of epithelial cells with periodate or neuraminidase. b. bron ... | 1987 | 3036708 |
| bordetella parapertussis and bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes. | pertussis toxin, the major virulence factor of bordetella pertussis, is not produced by the closely related species bordetella parapertussis and bordetella bronchiseptica. it is shown here that these two species possess but do not express the complete toxin operon. nucleotide sequencing of an ecori fragment of 5 kilobases comprising the regions homologous to the pertussis toxin genes shows that in this region, b. parapertussis and b. bronchiseptica are 98.5% and 96% homologous, respectively, to ... | 1987 | 3584073 |
| a note on the isoprenoid quinone content of bordetella avium and related species. | the isoprenoid quinone content of isolates of bordetella avium (four strains), alcaligenes faecalis (one strain), bordetella bronchiseptica (one strain) and a bordetella avium-like organism (four strains) was determined by reverse-phase high-performance liquid chromatography. all the isolates contained ubiquinones with eight isoprene units as the major component. no menaquinones were detected. | 1987 | 3597205 |
| effect of antigenic modulation and phase variation on adherence of bordetella bronchiseptica to porcine nasal epithelial cells. | in parallel with bacterial density, bordetella bronchiseptica phase-i, x-mode cells adhered well to porcine nasal epithelial cells, whereas c-mode cells and variant cells in phases ii, iii, and rough adhered feebly. cell surface components lost, on transition from x to c mode or from phase i to degraded phases, may confer much of the organism's adherence ability. | 1987 | 3434914 |
| the primary and secondary cellular immune responses to whole cell bordetella pertussis vaccine and its components. | the cellular immune responses of balb/c mice and wistar rats immunized in hind footpads with intact killed bordetella pertussis were found to differ from those of similar animals immunized with other bacteria including bordetella bronchiseptica, salmonella typhimurium and escherichia coli. all the bacteria stimulated increases in cell number, proliferation and interleukin 2 (il-2) production in popliteal lymph nodes which peaked 3-5 days after injection and decreased to resting levels by day 7. ... | 1987 | 3498569 |
| bordetella bronchiseptica and toxigenic type d pasteurella multocida as agents of severe atrophic rhinitis of swine. | bordetella bronchiseptica and toxigenic type-d pasteurella multocida were cultured from pigs in each of five herds diagnosed as having severe atrophic rhinitis (ar). b. bronchiseptica alone, p. multocida alone, or both organisms isolated from four herds were inoculated intranasally into 1-week-old gnotobiotic pigs which were necropsied 4 weeks post-inoculation (pi). nasal turbinate atrophy in b. bronchiseptica-inoculated pigs was moderate to severe, while p. multocida-inoculated pigs had slight ... | 1987 | 3564360 |
| bordetella bronchiseptica bronchitis. | the clinical course of a patient with bronchitis caused by bordetella bronchiseptica is described. the organism was recovered on one occasion from a protected catheter brush specimen obtained at bronchoscopy and on two occasions from expectorated sputum specimens. the infection was eradicated with antimicrobial therapy. | 1987 | 3571462 |
| bordetella bronchiseptica pneumonia in a patient with chronic lymphocytic leukemia. | this case report describes two episodes of pneumonia caused by bordetella bronchiseptica in a patient with chronic lymphocytic leukemia. there was discrepancy between the in vitro sensitivity testing of the organism and subsequent clinical response to several antimicrobial agents. human infection with b bronchiseptica is almost always associated with severe underlying disease and contact with an appropriate animal reservoir. | 1987 | 3629325 |
| [suitability of laboratory mouse strains for virulence testing of bordetella bronchiseptica]. | 1987 | 3632239 | |
| [cultivation of bordetella bronchiseptica in nutrient media with known amino acid content]. | 1987 | 3606325 | |
| increase in intradermal vascular permeability caused by pertussis toxin from bordetella pertussis. | rabbits that were injected intradermally with pertussis toxin (pt), produced from bordetella pertussis, showed slight edema and erythema at the injection sites, but not hemorrhage nor necrosis. the edema lesions were stained blue by the intravenous injection of pontamine sky blue 6b dye, suggesting that pt caused increased vascular permeability, similarly to the permeability factor (pf) of cholera toxin. the reaction of the pf of pt could be determined by measuring the diameter of the blue area. ... | 1987 | 2890084 |
| stimulation of bone resorption by inflamed nasal mucosa, dermonecrotic toxin-containing conditioned medium from pasteurella multocida, and purified dermonecrotic toxin from p. multocida. | the effects of inflamed nasal mucosa from pigs with atrophic rhinitis (ar), cell extract from bordetella bronchiseptica, conditioned medium from pasteurella multocida, and purified dermonecrotic toxin (dnt) from p. multocida on mouse fetal long bones in organ culture were studied. inflamed nasal "ar mucosa" stimulated the release of 45ca from prelabeled cultures, while histologically the formation of calcified matrix was impaired as well. b. bronchiseptica cell extract only transiently increased ... | 1987 | 3623695 |
| evolutionary relationships in the genus bordetella. | the nucleotide sequence of the pertussis toxin operon of bordetella pertussis, bordetella parapertussis and bordetella bronchiseptica, has shown that the last two species contain many common mutations and are likely to derive from a common ancestor (aricò and rappuoli, 1987). to elucidate further the evolutionary relationships between the bordetella species, we have cloned and sequenced the promoter region and the gene coding for the s1 subunit of pertussis toxin from additional b. pertussis str ... | 1987 | 2896289 |
| characterization of fimbrial subunits from bordetella species. | using antisera raised against serotype 2 and 3 fimbrial subunits from bordetella pertussis, serologically related polypeptides were detected in bordetella bronchiseptica, bordetella parapertussis and bordetella avium strains. the two b. pertussis fimbrial subunits, and three of the serologically related b. bronchiseptica polypeptides, were shown to be very similar in amino acid composition and n-terminal amino acid sequence. homology was observed between the n-termini of these polypeptides, and ... | 1987 | 2907088 |
| promoter of the pertussis toxin operon and production of pertussis toxin. | pertussis toxin (pt), the major virulence factor of bordetella pertussis, is composed of five different subunits whose genes are organized as an operon. we report the mapping of the promoter region of the pt operon and show that this promoter is only weakly active in escherichia coli. bordetella parapertussis and bordetella bronchiseptica, which do not produce any pt, are shown to have a weaker promoter sequence for this operon and not to produce any detectable pt mrna. we show that transcriptio ... | 1987 | 2438270 |
| structural and functional properties of a 69-kilodalton outer membrane protein of bordetella pertussis. | a-69-kda outer membrane protein present on virulent bordetella pertussis cells is recognized by the agglutinating monoclonal antibodies bpe3, bpd8, and bpe8. the amino acid composition of this protein, purified from heat extracts of b. pertussis bp353 cells, is different from that of the two major fimbrial antigens of b. pertussis, which is consistent with its being a nonfimbrial protein based on other criteria. western blot analysis using the monoclonal antibody bpe3 demonstrated that a slightl ... | 1988 | 2908522 |
| positive regulation of pertussis toxin expression. | although the genus bordetella contains several closely related species, pertussis toxin (pt) is produced only by phase i bordetella pertussis. in this work we have studied the regulation of expression of the pt operon and investigated why pt is produced by phase i and not by phase iii b. pertussis despite the presence of the pt genes. we have constructed a vector for bordetella species that contains the pt promoter fused to the coding region of the chloramphenicol acetyltransferase (cat) gene, a ... | 1988 | 2897691 |
| [detection of the gene sequences of the leukocytosis (lymphocytosis)-stimulating factor of bordetella pertussis in bordetella parapertussis and bordetella bronchiseptica by using molecular hybridization]. | the 4.7 kb ecori-fragment of phase i b. pertussis 475 (serovar 1.2.3) chromosome dna carrying the pertussis toxin (pt) operon was cloned on vector plasmid puc19 in escherichia coli. three fragments (1.14 kb kpni-psti, 1.27 kb psti-psti, and 0.96 kb psti-psti) were obtained from the resulting hybrid plasmid, coded prh119, by electrophoretic techniques and used as a combined molecular probe for analysis of the ecori-digested and psti-digested chromosomal dna of b. pertussis strain 475 in phase i, ... | 1988 | 2901175 |
| electron microscopic observations on tracheal epithelia of mice infected with bordetella bronchiseptica. | to clarify the pathogenesis of bordetella in vivo infection, the tracheal epithelia of mice were examined in detail by electron microscopy at various intervals after intranasal inoculation with graded doses of phase i bordetella bronchiseptica. in mice infected with a lethal dose (6 to 7 x 10(7) cfu), a remarkable rupture of the cell membranes of cilia and microvilli of the middle trachea was found on day i postinfection. the rupture of the membrane was observed over the entire tracheal epitheli ... | 1988 | 3173144 |
| [the use of ultrasound-treated amd complete bordetella bronchiseptica antigens in an indirect enzyme immunoassay]. | 1988 | 3178398 | |
| development of turbinate lesions and nasal colonization by bordetella bronchiseptica and pasteurella multocida during long-term exposure of healthy pigs to pigs affected by atrophic rhinitis. | natural transmission of atrophic rhinitis from pigs from a herd with an endemic atrophic rhinitis problem to pigs from a herd free of atrophic rhinitis was demonstrated. six replicates each with five pigs from the endemic atrophic rhinitis herd (group a) and five pigs from the atrophic rhinitis-free herd (group b) were housed together from 5 wk of age, with each replicate kept in isolation rooms maintained at optimal and controlled environmental conditions. three replicates each with six pigs/ro ... | 1988 | 3349398 |
| adherence of bordetella bronchiseptica and pasteurella multocida to porcine nasal and tracheal epithelial cells. | the ability of 19 different bordetella bronchiseptica isolates and 25 pasteurella multocida isolates to adhere in vitro to porcine nasal and tracheal epithelial cells was examined. it was found that b. bronchiseptica adhered well to upper respiratory tract cells. in contrast the number of p. multocida organisms which adhered was four to six times less than the number of b. bronchiseptica adherent organisms. this difference was statistically significant (p less than 0.0001). both microorganisms a ... | 1988 | 3370564 |
| bovine erythrocyte-agglutinin as a possible adhesin of bordetella bronchiseptica responsible for binding to porcine nasal epithelium. | the bovine erythrocyte-agglutinin (bea) of bordetella bronchiseptica, located on the cell surface in non-fimbrial form, has been identified as a possible adhesion responsible for binding to porcine nasal epithelium in studies with bea-negative (bea-) mutants and in competitive studies with bovine erythrocytes. | 1988 | 3392727 |
| [the differentiation of bordetella bronchiseptica strains. 7. phenotypic changes in bordetella bronchiseptica through changes of phase]. | 1988 | 3395180 | |
| the pathogenesis of turbinate atrophy in pigs caused by bordetella bronchiseptica. | the pathogenicity of 3 strains of bordetella bronchiseptica designated b58, pv6 and b65 was compared by intranasal infection of gnotobiotic piglets. strain b58 was a phase 1 isolate that produced haemolysin, an adhesin for calf erythrocytes, adenylate cyclase, mouse lethal factor, dermonecrotic factor and cytotoxin. b65 was a variant of b58 that produced no detectable haemolysin, adhesin or adenylate cyclase and 10-fold smaller amounts than b58 of mouse lethal factor, dermonecrotic factor and cy ... | 1988 | 3218075 |
| [the differentiation of bordetella bronchiseptica strains. 5. virulence factors in relation to phase changes in bordetella bronchiseptica strains]. | 1988 | 3219030 | |
| [the differentiation of bordetella bronchiseptica strains. 6. detection of adhesion in bordetella bronchiseptica]. | 1988 | 3219031 | |
| in vitro susceptibility of bacteria to a ticarcillin-clavulanic acid combination. | in vitro testing of bacterial susceptibility to a combination of ticarcillin and clavulanic acid was done, using 406 aerobic gram-positive and gram-negative isolates (considered to be pathogens) cultured from equine and small animal specimens. a microdilution broth technique of susceptibility testing was performed, using trays with wells containing a range of doubling concentrations of dehydrated ticarcillin (range, 0.50 to 128 micrograms/ml) with fixed concentration of clavulanic acid (4 microg ... | 1988 | 3239838 |
| isolation and characterization of mutant strains of bordetella bronchiseptica lacking dermonecrotic toxin-producing ability. | mutant strains of bordetella bronchiseptica, named b-42, b-76, b-84, and b-119, were obtained after serial passages of a parent strain, l3, on bordet-gengou agar plates containing 20% horse blood and 200 micrograms of nalidixic acid per ml (bgn-20 agar plates) at 42 degrees c. mutant strains completely lacked dermonecrotic toxin-producing ability, and lethal activity of the strains for mice was apparently reduced compared with that of strain l3. mutant strains were able to grow at 42 degrees c, ... | 1988 | 3182989 |
| induction of nasal turbinate atrophy in germ-free pigs, using pasteurella multocida as well as bacterium-free crude and purified dermonecrotic toxin of p multocida. | to establish the role of the dermonecrotic toxin (dnt) of pasteurella multocida in the cause and pathogenesis of atrophic rhinitis, germ-free pigs were inoculated with several strains of p multocida, crude dnt, or purified dnt. in some experiments, the aforementioned inocula were combined with bordetella bronchiseptica. all dnt-producing p multocida strains induced severe turbinate atrophy. histologic examination of the remnants of the nasal turbinates revealed intact, but undulated, ciliated ep ... | 1988 | 3247905 |
| decrease in antimicrobial susceptibility of bordetella bronchiseptica caused by antigenic modulation and phase variation. | the susceptibilities to 20 antimicrobial agents of bordetella bronchiseptica variants in c mode and degraded phases were compared with those of their parents in x mode. increases in mics of 4- to 32-fold were observed for ampicillin, carbenicillin, erythromycin, novobiocin, rifampin, chloramphenicol, nalidixic acid, and oxolinic acid. | 1988 | 3245700 |
| monoclonal antibody-based sandwich enzyme-linked immunosorbent assay for detection of bordetella pertussis filamentous hemagglutinin. | hybrid cell lines producing monoclonal antibodies against bordetella pertussis filamentous hemagglutinin (fha) were established. the specificity of the antibodies was ascertained by enzyme-linked immunosorbent assay (elisa), sandwich elisa, and sodium dodecyl sulfate-polyacrylamide gel electrophoresis followed by electroblotting. the monoclonal antibody-based sandwich elisa was developed for detection of b. pertussis fha. the assay had a detection limit of b. pertussis fha in concentrations rang ... | 1988 | 2903174 |
| studies on the antigenic relationships of six adherent isolates of bordetella bronchiseptica. | six isolates of bordetella bronchiseptica recovered from swine with atrophic rhinitis were studied. all hemagglutinated swine red blood cells, autoagglutinated in saline and showed fimbriae by electron microscopy. hyperimmune sera against each were produced in rabbits and the antigenic relationships between the isolates were studied by cross-absorption and by the determination of the cross-reactivity indices of pairs of sera. three isolates seemed to be identical by both methods, while 2 others ... | 1988 | 2906770 |
| epizootiological studies on porcine atrophic rhinitis. xv. results of local immunization with a live bordetella bronchiseptica strain in a large-scale pig herd affected by atrophic rhinitis. | 1988 | 2978213 | |
| electron microscopic observations of ciliated epithelium of mouse trachea treated in vitro with a membrane-damaging factor from bordetella bronchiseptica. | 1988 | 3253469 | |
| adherence of pasteurella multocida or bordetella bronchiseptica to the swine nasal epithelial cell in vitro. | the interaction of bordetella bronchiseptica or pasteurella multocida with swine nasal epithelial cells was studied in vitro. the mean number of b. bronchiseptica organisms adhered per cell was about three times as high as that of p. multocida (p less than 0.01), and the adherence was specifically inhibited by the homologous antiserum prepared with the whole-cell antigen of each bacterium. the poor affinity of p. multocida to the swine nasal mucosa as compared with that of b. bronchiseptica was ... | 1988 | 3335403 |
| an evaluation in pigs of nobi-vac ar and an experimental atrophic rhinitis vaccine containing p multocida dnt-toxoid and b bronchiseptica. | the trial involved eight large white sows obtained from a closed experimental specific pathogen free herd. four sows (two each for an experimental vaccine and for nobi-vac ar) were vaccinated twice (eight weeks and two weeks before parturition) with 2 ml of vaccine administered intramuscularly. two unvaccinated sows were used as an infected control group and two unvaccinated sows served as an uninfected control group. forty-six piglets (28 from vaccinated sows and 18 from unvaccinated sows) were ... | 1989 | 2919495 |
| atrophic rhinitis in new zealand white rabbits infected with pasteurella multocida. | atrophic rhinitis was detected in new zealand white rabbits when upper respiratory tract disease was evaluated during a vaccine field trial for the prevention of pasteurellosis. of 52 adult rabbits euthanatized and necropsied, 26 (50%) had evidence of turbinate atrophy. atrophy was detected in 77% of rabbits with pasteurella multocida infection only, 71% of rabbits with concurrent p multocida and bordetella bronchiseptica infections, and 6% of rabbits with b bronchiseptica infection only. grossl ... | 1989 | 2802315 |
| infection with and antibody response to pasteurella multocida and bordetella bronchiseptica in immature rabbits. | at 2, 4, 6, 8 and 10 weeks of age rabbits were cultured for pasteurella multocida and bordetella bronchiseptica from the paranasal sinuses, trachea, middle ears, lungs and liver. sera were tested for antibodies (igg) against p. multocida and b. bronchiseptica. pasteurella multocida was isolated from all ages of rabbits, and b. bronchiseptica was isolated from rabbits 4 to 10 weeks old. the sinuses were colonized most often, followed by the trachea, middle ears and lungs. no bacteria were isolate ... | 1989 | 2811279 |
| differences in virulence between two strains of streptococcus suis type ii after experimentally induced infection of newborn germ-free pigs. | fifteen newborn germ-free pigs were inoculated with 2 strains, d-282 and t-15, of streptococcus suis type ii. some pigs also were preinoculated with bordetella bronchiseptica, which successfully predisposed them to s suis infection. the 2 streptococcal strains were differentiated by muramidase treatment, which released certain high molecular-weight proteins, termed muramidase-released proteins (mrp), from the cell wall of strain d-282, but not from the cell wall of strain t-15. only strain d-282 ... | 1989 | 2774320 |
| [stimulation of nonspecific immune defense and antibody synthesis with zymosan]. | a local sterile inflammation was induced in mice of different inbred strains by means of an i.p. injection of zymosan, a water-insoluble polysaccharide of the cell wall of saccharomyces cerevisiae. this resulted in a strong enhancement of the unspecific resistance against infections with a ld 90 of gram-negative bacteria (escherichia coli, pseudomonas aeruginosa, klebsiella pneumoniae and bordetella bronchiseptica). furthermore, the treatment with zymosan before or after an immunization with she ... | 1989 | 2718888 |
| efficacy of a commercial bacterin in protecting strain 13 guineapigs against bordetella bronchiseptica pneumonia. | bordetella bronchiseptica is known to be endemic in many guineapig (cavia porcellus) colonies, and periodically is the aetiological agent of fatal epizootics of bronchopneumonia. a commercial, non-adjuvant b. bronchiseptica bacterin, which is approved for use in canines, was evaluated for induction of a protective immune response in strain 13/n guineapigs against an airborne challenge of virulent b. bronchispeptica in small-particle aerosol. seronegative animals were vaccinated on days 0 and 21 ... | 1989 | 2761230 |
| pasteurella multocida and bordetella bronchiseptica in atrophic rhinitis and pneumonia in swine. | a total of 163 pigs from nine farrow-to-finish herds representing various levels of atrophic rhinitis (ar) were selected for postslaughter examination of ar and pneumonia. nasal swabs and lungs were cultured for detection of bordetella bronchiseptica and pasteurella multocida. seventy-three pigs were examined at eight weeks of age and 90 contemporaries at six months of age. mean ar scores were 1.21 and 1.11 for the eight week and six month old pigs, respectively (0 = normal, 3 = severe). in indi ... | 1989 | 2766151 |
| purification and characterization of bordetella bronchiseptica dermonecrotic toxin. | dermonecrotic toxin produced by bordetella bronchiseptica was purified by chromatography on deae toyopearl 650m and on bio-gel htp, gel filtration on sephadex g-200, and subsequent chromatography on bio-gel htp and on sp toyopearl 650m. the purified toxin was homogeneous by sodium dodecyl sulfate polyacrylamide gel electrophoresis and high performance liquid chromatography. there was a 90-fold increase in the dermonecrotic titer per mg protein in guinea pigs and the recovery of activity was 17.6 ... | 1989 | 2770506 |
| development of a rapid diagnostic test for pertussis: direct detection of pertussis toxin in respiratory secretions. | monoclonal antibodies (mab) were produced against the specific bordetella pertussis antigen pertussis toxin (pt). in preliminary studies, one mab (ib12) was selected and used in an enzyme-linked dot blot immunoassay to evaluate the ability of the method to detect known amounts of pt in control experiments and to test its potential for direct detection of pt in nasopharyngeal secretion (np) specimens from patients with confirmed cases of whooping cough. the dot blot assay was able to detect pt at ... | 1989 | 2808670 |
| flow microcalorimetric assay of antibiotics--i. polymyxin b sulphate and its combinations with neomycin sulphate and zinc bacitracin on interaction with bordetella bronchiseptica (nctc 8344). | a flow microcalorimetric assay for polymyxin b sulphate has been developed which has a better reproducibility (relative standard deviation less than 3%) and sensitivity (0.35 micrograms ml-1) than conventional microbiological assays, and requires an assay time of ca. 4.5 h. the combinations with zinc bacitracin, with neomycin sulphate, and with both zinc bacitracin and neomycin sulphate indicate antagonism between these antibiotics upon interaction with bordetella bronchiseptica (nctc 8344). the ... | 1989 | 2490093 |
| protection against progressive atrophic rhinitis by vaccination with pasteurella multocida toxin purified by monoclonal antibodies. | pasteurella multocida toxin was purified by affinity chromatography and inactivated by treatment with formaldehyde before use as a single component vaccine against progressive atrophic rhinitis in pigs. twenty pregnant gilts which were vaccinated twice before farrowing with either low or high doses of the purified toxoid, developed dose-dependent positive serum and colostrum titres to the toxin and, unlike the progeny of 10 untreated control gilts, the offspring of the vaccinated gilts also had ... | 1989 | 2528856 |
| phase variants of bordetella bronchiseptica arise by spontaneous deletions in the vir locus. | bordetella bronchiseptica is a common respiratory tract pathogen of many mammalian species. nucleotide sequences from the locus involved in coordinate regulation of b. pertussis virulence factors, vir, were shown to have a high degree of homology to chromosomal dna from virulent (vir+) and avirulent (vir-) strains of b. bronchiseptica. small deletions, 50 bp to 500 bp, within the vir locus were found in some of the vir- phase variants. the vir locus and the adjacent 5' portion of the fhab struct ... | 1989 | 2560120 |
| induction of bronchial hyperresponsiveness by bordetella bronchiseptica infection in dogs. | six beagles were examined for time-related changes of bronchial responsiveness to methacholine, plasma histamine and thromboxane b2, and biopsy of bronchial tissues after intratracheal injection of bordetella bronchiseptica. a progressive increase in bronchial responsiveness was induced after injection. the mediators, however, did not elevate and tissue neutrophil counts did not correlate with increased airway hyperresponsiveness. intratracheal injection of heat-killed bordetella bronchiseptica ... | 1989 | 2643371 |
| [infectious factor diseases in domestic small animals (carnivorous and herbivorous fur animals, wool and meat rabbits]. | infectious factorial diseases of domesticated small animals are infection dependent diseases, whose pathogenesis is finally activated by additional, secondary factors, that influence the multiplying and spreading of latent and clinical symptomless infective agents present in the animals. these factorial diseases are not autonomous infectious processes, but only special types and courses of diseases by secondary activated infective agents. secondary factors may be of exogenous origin (housing, cl ... | 1989 | 2686619 |
| expression of pertussis toxin in bordetella bronchiseptica and bordetella parapertussis carrying recombinant plasmids. | pertussis toxin is produced only by strains of bordetella pertussis. cloned genes encoding pertussis toxin from b. pertussis were transferred into bordetella bronchiseptica and bordetella parapertussis by conjugation. these transconjugants expressed pertussis toxin at levels comparable to those expressed by b. pertussis. the toxin made by these strains was biologically active in the chinese hamster cell clumping assay, contained all five subunits, and was mostly periplasmic. toxin expression app ... | 1989 | 2707851 |
| interactions between bordetella bronchiseptica and toxigenic pasteurella multocida in atrophic rhinitis of pigs. | three strains of bordetella bronchiseptica were compared for their ability to assist colonisation of the nasal cavity of gnotobiotic pigs by toxigenic pasteurella multocida. toxigenic p multocida (counted in nasal washings) colonised the cavity in large numbers in pigs previously infected with a cytotoxic phase i strain of b bronchiseptica (b58), whereas it colonised only in small numbers in those previously infected with b65, a phenotypic phase iii variant of b58. toxigenic p multocida colonise ... | 1989 | 2772406 |
| in vitro antimicrobial activity of sulfonamides against some porcine pathogens. | the minimal inhibitory concentrations (mic) of sulfonamides were determined against bordetella bronchiseptica (n = 10), pasteurella multocida (n = 10), haemophilus pleuropneumoniae (n = 20), and streptococcus suis (n = 10) strains isolated from pigs with atrophic rhinitis, pneumonia, or meningitis. sulfonamides tested in an agar dilution method were sulfachloropyridazine, sulfadiazine, sulfadimethoxine, sulfamethazine, sulfadoxine, sulfisoxazole, sulfamerazine, sulfamethoxazole, sulfamethoxypyri ... | 1989 | 2774319 |
| novel phase-shift marker in cell surface proteins of bordetella bronchiseptica. | cell surface proteins of phase i cultures of bordetella bronchiseptica strains from various species of animals were compared with those of isogenic phase iii cultures by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. a protein band with a molecular mass of 74 kilodaltons was found only in various phase i cultures. this protein disappeared in parallel with antigenic modulation and had strong antigenicity. we found it to be an appropriate phase-shift marker for two reasons: it was read ... | 1989 | 2745684 |
| antimicrobial susceptibility of bordetella avium and bordetella bronchiseptica isolates. | two veterinary pathogens, bordetella bronchiseptica and bordetella avium, were tested for their antimicrobial susceptibilities. of the 20 antimicrobial agents tested, both species were consistently resistant to penicillin and cefuroxime but susceptible to mezlocillin, piperacillin, gentamicin, amikacin, and cefoperazone. | 1989 | 2751288 |
| electron microscopic observations on ciliated epithelium of tracheal organ cultures infected with bordetella bronchiseptica. | using mouse tracheal organ cultures, the pathogenic effect of bordetella bronchiseptica to epithelial cells was studied by electron microscopy. the ultrastructure of epithelial cells in uninfected tracheal rings was preserved well for longer than 3 days. in mouse tracheal rings infected with graded doses (3 x 10(5) to 10(7) cfu/ml) of phase i b. bronchiseptica, the colonization in the interciliary spaces of ciliated epithelial cells was observed after a 20-hr infection period. the infected trach ... | 1989 | 2716544 |
| residue determination of two co-administered antibacterial agents--cephalexin and colistin--in calf tissues using high-performance liquid chromatography and microbiological methods. | residues of two antibacterial agents, cephalexin and colistin, co-administered by intramuscular injection to calves, were quantified in four different tissues (muscle, fat, liver and kidney) by column switching hplc and by a microbiological method. for cephalexin assay, tissue samples with cephradin as internal standard were homogenized in a 5% trichloroacetic acid solution and filtrates were injected onto a concentration precolumn filled with lichroprep rp-18 (25-40 microns). a clean-up step wa ... | 1989 | 2490572 |
| genetics of pertussis toxin. | pertussis toxin (pt) is the major virulence factor of bordetella pertussis. the cloning and nucleotide sequencing of the pt genes from b. pertussis, bordetella parapertussis and bordetella bronchiseptica has elucidated the evolution of the bordetella species and allowed considerable advances towards the understanding of their gene expression and the development of safer vaccines against pertussis. | 1989 | 2654538 |
| laboratory survey of fluoroquinolone activity. | fluoroquinolones are active against a wide variety of bacteria. the antibacterial spectra of fluoroquinolones encompass staphylococci, bacillus species, and corynebacterium species implicated in infections of the immunocompromised host; enterobacteriaceae; most intestinal pathogens; and many gram-negative organisms commonly causing nosocomial infections. haemophilus influenzae, haemophilus ducreyi, neisseria gonorrhoeae, neisseria meningitidis, and branhamella catarrhalis are highly susceptible ... | 1989 | 2672262 |
| [atrophic rhinitis of swine--a multifactorial disease?]. | atrophic rhinitis is caused by toxigenic pasteurella multocida strains. the infection is supported by bordetella bronchiseptica and other widespread agents and by non-infectious factors damaging the nasal epithelium. the term "infectious multifactorial disease" means in german, that ubiquitous low-virulent agents cause disease when intensified by non-infectious factors. atrophic rhinitis does not belong to this group but is an infectious disease, caused by a specific agent and influenced by seve ... | 1989 | 2686620 |
| in vitro evaluation of various quinolone antibacterial agents against veterinary mycoplasmas and porcine respiratory bacterial pathogens. | the in vitro activities of 12 quinolones and four antibiotics were determined against 15 veterinary mycoplasmal species and four species of bacteria commonly involved in respiratory infections in pigs. the newer quinolones were markedly more active in vitro against a wide range of mycoplasmas than nalidixic acid and the earlier quinolones. against mycoplasma hyopneumoniae ciprofloxacin was the most active quinolone with a geometric mean minimal inhibitory concentration (mic) against 16 strains o ... | 1989 | 2704885 |
| the influence of growth conditions of pasteurella multocida on its ability to colonise the nasal mucosa of spf piglets. | colonisation of type d pasteurella multocida was studied in five groups of seven spf piglets each. piglets of group 1 were kept together with seven 5-week-old piglets obtained from a large herd infected with toxigenic p. multocida for 16 weeks (contact infection). these piglets were made free from toxigenic bordetella bronchiseptica by local immunisation. piglets of group 2 were inoculated with 5 x 10(7) colony-forming units (cfu) of p. multocida washed from the nasal mucosa of piglets free from ... | 1990 | 2145686 |
| a comparison of different challenge methods for induction of atrophic rhinitis in pigs. | transmission and development of atrophic rhinitis (ar) was studied in 5- to 15-week-old pigs (groups 2-7) originating from a herd free of ar, and compared to unexposed healthy pigs (group 1), and pigs from a herd with endemic ar (group 8). at the start of the trial, pigs in groups 2-5 were challenged intranasally twice a week for 3 weeks with pure cultures of bacteria originating from the endemic ar herd: nontoxigenic pasteurella multocida type a (pma) plus bordetella bronchiseptica phase i (bb) ... | 1990 | 2357344 |
| adherence of bordetella bronchiseptica and pasteurella multocida to swine nasal ciliated epithelial cells in vitro. | a bacterial adherence assay using swine nasal turbinate fragments was established. turbinate fragments were incubated with bordetella bronchiseptica or pasteurella multocida type d at different concentrations or for different incubation times at 37 degrees c on a shaker at 120 rev/min. b. bronchiseptica phase i strains exhibited strong adherence to swine nasal ciliated epithelial cells. the number of adherent bacteria per cell increased when the bacterial concentration or incubation time increas ... | 1990 | 2357345 |
| hydrophobic surface properties of bordetella bronchiseptica x-mode cells and their possible role in adherence to porcine nasal mucosa. | bordetella bronchiseptica strains were examined to determine whether the surface hydrophobicity of the bacteria correlates with their adherence to porcine nasal epithelial cells. the relative hydrophobicity of the bacteria, measured by their retention to a column of hydrophobic phenyl-sepharose gel and their aggregation in ammonium sulfate solution, correlated well with their adhesive properties. phase i cells in x-mode, which adhered well to the epithelial cells, were conspicuously hydrophobic. ... | 1990 | 2357669 |
| bordetella bronchiseptica bronchitis in an immunosuppressed patient. | 1990 | 2373090 | |
| clinical and pathological effects of the dermonecrotic toxin of bordetella bronchiseptica and pasteurella multocida in specific-pathogen-free piglets. | the role of dermonecrotic toxin (dnt) of bordetella bronchiseptica and pasteurella multocida, purified by repeated chromatography in sephacryl s-200 gel, in the pathogenesis of atrophic rhinitis (ar) of swine was studied bacteriologically, clinically and pathologically. two-week-old specific pathogen-free (spf) piglets were parenterally treated with 30 micrograms of dnt 3 times at 2-day interval and 7-week-old piglets were treated with 15 micrograms of dnt twice a week for 5 weeks. in 2- to 3-we ... | 1990 | 2144027 |
| effects of bordetella bronchiseptica dermonecrotic toxin on structure and function of osteoblastic clone mc3tc-e1 cells. | 1990 | 2101152 | |
| molecular aspects of the virulence of pasteurella multocida. | molecules important to the virulence of all pasteurella multocida are little known, but much has been learned of isolates causing atrophic rhinitis of pigs. a protein toxin purified from p. multocida or from a recombinant escherichia coli reproduces atrophic rhinitis and leads to a reduction in weight gain; antitoxin is completely protective. toxin is important for p. multocida colonization, especially in the presence of the bordetella bronchiseptica cytotoxin. the p. multocida toxin binds rapid ... | 1990 | 2193704 |
| [studies on immunity to babesia gibsoni in dogs immunostimulation by bordetella bronchiseptica]. | four species of bacteria, corynebacterium anaerobium 578, actinobacillus pleuropneumoniae g-4, mycobacterium bovis bcg, and bordetella bronchiseptica a-2, were injected intravenously into mice (5 weeks old, icr-spf). the clearance of carbon from the blood stream and the weights of the spleen and liver were determined as indicators of res stimulation. mouse footpad reaction was assessed as an indicator of delayed-type hypersensitivity to each species of bacteria. the immuno-stimulative activity o ... | 1990 | 2232161 |
| drug-susceptibility and isolation of a plasmid in haemophilus (actinobacillus) pleuropneumoniae. | we isolated 56 haemophilus (actinobacillus) pleuropneumoniae strains from the pneumonic porcine lung tissues and tested them for antimicrobial susceptibility. two drug-resistant strains were obtained. one, named kh-265, was resistant to streptomycin (sm) and sulfonamide (sa), and the other, named kh-195, was resistant to tetracycline (tc). the minimum inhibitory concentrations (mics) of drugs for resistant strains were 100 micrograms/mliters for sm, 3200 micrograms/mliters for sa, and 12.5 micro ... | 1990 | 1968988 |
| [human infection by bordetella bronchiseptica]. | 1990 | 2090221 | |
| immunopathological changes in mice caused by bordetella bronchiseptica and pasteurella multocida. | the immunopathological changes induced by toxigenic pasteurella multocida, toxigenic phase i bordetella bronchiseptica and its phase iii variant were studied. four groups of mice, each containing 21 animals, were inoculated intravenously with sublethal doses of b. bronchiseptica as follows: group 1: phase i toxigenic b. bronchiseptica whole-cell suspension (wcs); group 2: phase iii b. bronchiseptica wcs; group 3: phase i b. bronchiseptica sonicated extract (se); and group 4: phase iii b. bronchi ... | 1990 | 2099605 |
| the pathology of experimental respiratory infection with pasteurella multocida and bordetella bronchiseptica in rabbits. | groups of female new zealand white rabbits, 8-10 weeks old, were inoculated intranasally with three different pasteurella multocida serotypes (a:3, a:4 and a:12) or one of three bordetella bronchiseptica strains of rabbit origin. seven out of 18 rabbits died of experimental infection with p. multocida. b. bronchiseptica killed 3 out of the 8 animals inoculated with it. deaths occurred between 3 and 6 days postinoculation (pi). in the rabbits that died of p. multocida inoculation, necropsy and hi ... | 1990 | 2099606 |
| canine parainfluenza type 2 bronchiolitis increases histamine responsiveness in beagle puppies. | histamine hyperresponsiveness with viral bronchiolitis may depend on previous exposures to viruses or to other pathogens. we studied 32 outbred beagle puppies 80 to 155 days of age who were raised in isolation and who were specific pathogen-free. puppies were inoculated with canine parainfluenza type 2 (cpi2, n = 8), bordetella bronchiseptica (bb, n = 7), or both cpi2 and bb (cpi2-bb, n = 9). control puppies (c, n = 8) were not inoculated. the puppies were anesthetized with sodium thiopental (5 ... | 1990 | 2153354 |
| analysis of a repetitive dna sequence from bordetella pertussis and its application to the diagnosis of pertussis using the polymerase chain reaction. | a tandemly repeated 1,046-base-pair (bp) clai dna fragment from bordetella pertussis was cloned into escherichia coli by using the vector puc19. this fragment, when isolated, hybridized strongly to dna from all 100 clinical isolates of b. pertussis tested. it was shown to have homology to single-copy sequences in bordetella bronchiseptica but not bordetella parapertussis and did not hybridize to lysate blots of a wide range of other bacteria, including members of the closely related genera paste ... | 1990 | 2229381 |
| serological, bacteriological and clinical observations on an outbreak of canine infectious tracheobronchitis in norway. | during the autumn of 1988 an outbreak of canine infectious tracheobronchitis, which seemed to be more infectious than usual, occurred throughout scandinavia. paired serum samples and bacterial swabs were collected from 52 dogs with clinical signs of infectious tracheobronchitis in three districts of norway. the results revealed a fourfold or greater rise in the titre of antibodies against canine parainfluenza virus in 79 per cent of the cases, strongly suggesting that the virus was of aetiologic ... | 1990 | 2161580 |
| in vitro susceptibility of some porcine respiratory tract pathogens to aditoprim, trimethoprim, sulfadimethoxine, sulfamethoxazole, and combinations of these agents. | the in vitro antimicrobial activities of aditoprim (ap), a new dihydrofolate reductase (dhfr) inhibitor, trimethoprim (tmp), sulfadimethoxine (sdm), sulfamethoxazole (smx), and combinations of these drugs against some porcine respiratory tract pathogens were determined by use of an agar dilution method. the minimal inhibitory concentrations (mic) of these agents were determined twice against bordetella bronchiseptica (n = 10), pasteurella multocida (n = 10), and actinobacillus pleuropneumoniae ( ... | 1990 | 2240813 |
| determination of an antigen suitable for enzyme-linked immunosorbent assay of the antibody to bordetella bronchiseptica in guinea pigs. | to establish an enzyme-linked immunosorbent assay (elisa) technique for the serological diagnosis of infections caused by bordetella bronchiseptica (b. bronchiseptica) in guinea pigs, the authors recently assessed the usefulness of three antigen preparations derived from the bacterial cell components: sonication antigen (s-ag), cell surface antigen (c-ag) and lipopolysaccharide antigen (l-ag). the use of s-ag for elisa resulted in the most sensitive detection of the antibody to b. bronchiseptica ... | 1990 | 2242767 |
| pasteurella multocida and bordetella bronchiseptica infections in rabbits. | the natural history of infection with pasteurella multocida and bordetella bronchiseptica in domestic rabbits was studied prospectively at a commercial rabbitry. at weaning, about 25% of rabbits had nasal infections with p. multocida and 75% had infections with b. bronchiseptica. infection of weanling rabbits paralleled nasal infections of their dams. the proportion of rabbits with both infections increased with age. at 2 to 4 months old, about 50% of rabbits with p. multocida or p. multocida an ... | 1990 | 2298879 |
| simplified procedure for purification of bordetella bronchiseptica dermonecrotic toxin. | bordetella bronchiseptica dermonecrotic toxin was purified by a simplified method. the method consisted of sp toyopearl 650m chromatography and high performance liquid chromatography on a tsk gel g3000sw column. 47.5% of the activity of the crude cell extract was recovered. the purified toxin behaved as a homogeneous protein in sodium dodecyl sulfate polyacrylamide gel electrophoresis, high performance liquid chromatography, and agar gel double diffusion tests. | 1990 | 2323545 |
| interstitial pneumonia caused by bordetella bronchiseptica in a heart transplant patient. | 1990 | 2326878 |