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a suggested mechanism for the pathogenesis of infectious atrophic rhinitis.boivin extracts of bordetella bronchiseptica inhibited or uncoupled the energized processes of bovine heart and pig heart mitochondria. energy-dependent accumulation of calcium phosphate by both types of mitochondria was markedly inhibited by the extracts. the thesis is advanced that boivin extracts of b. bronchiseptica may contain the membrane-damaging component responsible for infectious atrophic rhinitis. the action of the extracts was decreased by heat but seemed rather insensitive to digest ...19714260946
bordetella agglutinating antibody in swine. a herd survey.an agglutination test with killed bordetella bronchiseptica, suspended in 0.85% saline, standardized photometrically to contain approximately 20 billion microorganisms per ml as antigen, was used to detect naturally-occurring antibody against this bacterium in the sera of 451 pigs ranging in age from one month to over 36 months. agglutinating antibody was demonstrated in 32.8% of 201 sera of pigs one to six months old, 61.5% of 52 pigs six to 12 months old, 83.8% of 62 pigs 13 to 18 months old, ...19734270813
[action of bordetella pertussis, bordetella parapertussis and bordetella bronchiseptica on tissue cultures]. 19664295633
immunization of pigs against bordetella bronchiseptica infection by parenteral vaccination. 19724342331
the pathology and pathogenesis of bordetella bronchiseptica and pasteurella pneumotropica infection in conventional and germfree rats. 19724345304
bordetella bronchiseptica in laboratory cats from central california. 19734347755
pathology of experimental atrophic rhinitis in swine infected with alcaligenes bronchisepticus or pasteurella multocida. 19744444735
properties of r factors from bordetella bronchiseptica.genetic properties and host ranges of r factors derived from bordetella bronchiseptica of pig origin were examined. all of 61 r factors tested could confer resistance to streptomycin, sulfonamide, and aminobenzyl penicillin on their host bacteria. all of them were identified as fi(-) (no fertility inhibition) type and were found to exhibit no restriction of phages lambda, phi80, p1, p2, t1, t3, t6, t7, w31, and bf-23. they could confer macarbomysin susceptibility on their host cells when infecte ...19744451355
turbinate morphology in pigs inoculated with bordetella bronchiseptica and fed high or low calcium diets. 19744473319
the incidence of r factors in bordetella bronchiseptica isolated from pigs. 19744546951
progress in the control of atrophic rhinitis caused by bordetella bronchiseptica in swine. 19724565064
bordetella bronchiseptica: a re-assessment of its role in canine respiratory disease. 19734594840
properties of an r factor from bordetella bronchiseptica. 19744612099
lesions of experimental swine atrophic rhinitis and alcaligenes bronchisepticus antigen detected by fluorescent antibody technique. 19744616181
[occurrence and importance of bordetella bronchiseptica in rabbits]. 19724646424
development of resistance to reinfection of bordetella bronchiseptica in guinea pigs recovered from natural infection. 19724673845
agglutinin response of pigs to intranasal infection of bordetella bronchiseptica. 19734687068
bordetella bronchiseptica associated with infertility in a mare. 19734711579
respiratory tract disease associated with bordetella bronchiseptica infection in cats. 19734721767
studies on the etiology of infectious atrophic rhinitis of swine. iv. agglutination test with formolized antigen for bordetella bronchiseptica infection in pigs. 19734738925
demonstration of r factors in bordetella bronchiseptica isolated from pigs.transferability of drug resistance in strains of bordetella bronchiseptica isolated from pigs was examined. these strains were resistant to sulfadimethoxine (sa, more than 1,600 mug/ml), streptomycin (sm, more than 800 mug/ml), and aminobenzyl penicillin (apc, 200 mug/ml). all of them could transfer their drug resistance as one unit to a sensitive strain of escherichia coli as well as to b. bronchiseptica by mixed cultivation. the transferred sm-sa-apc resistance in the exconjugants of e. coli a ...19734790610
nasal turbinate atrophy in newborn rabbit infected with alcaligenes bronchisepticus of pig origin. 19734792273
studies on the etiology of infectious atrophic rhinitis of swine. v. experimental bordetella bronchiseptica infection in conventional piglets. 19734797137
[eradication of bordetella bronchiseptica from guinea pig colonies (author's transl)]. 19734799945
studies on the etiology of infectious atrophic rhinitis of swine. vi. effect of vaccination against nasal establishiment of bordetella bronchiseptica. 19734800055
bordetella bronchiseptica infections in germ-free swine: an experimental pneumonia. 19734802816
blood chemical changes in growing pigs exposed to aerosol of bordetella bronchiseptica. 19744819726
prophylaxis of bordetella bronchiseptica infection in guinea pigs by vaccination. 19744858744
homologies of deoxyribonucleic acids from brucella ovis, canine abortion organisms, and other brucella species.the bacterium that causes canine abortion has polynucleotide sequences similar, in deoxyribonucleic acid (dna)-dna homology studies, to those of brucella suis and, by inference from previous data, those of b. abortus and b. melitensis as well as b. neotomae. therefore, the organism causing canine abortion appears to be a member of the genus brucella. dna preparations from serratia marcescens, alcaligenes faecalis, and bordetella bronchiseptica, 58, 62, and 66 mole% guanine plus cytosine, respect ...19684882024
nasal and tracheal resistance of swine against reinfection by bordetella bronchiseptica. 19694978600
[etiological participation of pseudomonas aeruginosa, bordetella bronchiseptica and mycoplasma in porcine atrophic rhinitis]. 19715002947
experimental atrophic rhinitis produced by bordetella bronchiseptica culture in young pigs. 19725039612
equine bronchopneumonia caused by bordetella bronchiseptica. a case report. 19715103407
experimental bordetella bronchiseptica infection in guinea pigs. 19715105008
bordetella bronchiseptica pneumonia in guinea-pigs. description of the disease and elimination by vaccination. 19715114349
nasal lesions and alcaligenes bronchisepticus infection in swine atrophic rhinitis. 19715133418
atrophic rhinitis produced by intranasal inoculation of bordetella bronchiseptica in hysterectomy produced colostrum-deprived pigs. 19715166142
pathology of experimental bordetella bronchiseptica infection in swine: atrophic rhinitis. 19665335278
incidence of bordetella bronchiseptica in wildlife and man in iowa. 19665338544
studies on the etiology of infectious atrophic rhinitis of swine. ii. agglutination test on bordetella bronchiseptica infection. 19705531793
experimental bordetella bronchiseptica infection in embryonated eggs. 19675596139
taxonomic position in the genus brucella of the causative agent of canine abortion.the gram-negative organism causing abortion in dogs was examined in parallel with cultures representative of the brucella species and with bordetella bronchiseptica. the organism fits into the genus brucella and most closely resembles b. suis on the basis of its growth characteristics. it is of rough colonial morphology and is agglutinated by antisera prepared against rough brucella. in mouse toxicity tests, no endotoxic activity could be demonstrated. in contrast to most brucella cultures, it d ...19685689122
turbinate atrophy in young pigs exposed to bordetella bronchiseptica, pasteurella multocida, and combined inoculum. 19685689271
fine structural changes in the porcine nasal ciliated epithelial cell produced by bordetella bronchiseptica rhinitis. 19655891214
pathology of experimental bordetella bronchiseptica infection in swine: pneumonia. 19666006494
role of canine parainfluenza virus and bordetella bronchiseptica in kennel cough.the effect of bordetella bronchiseptica upper airway colonization on the clinical, radiographic, serologic, pathologic, and pulmonary function changes caused by canine parainfluenza-2 virus (cpiv-2) infection was studied in 24 purebred beagle pups (10.5 +/- 1.4 weeks old). eight control dogs (group i) were not colonized or inoculated with cpiv-2. of the 12 noncolonized dogs inoculated with cpiv-2 (group ii), 9 developed antibody titers to cpiv-2 and 10 had clinical signs of infectious canine tra ...19846093651
hemagglutination by bordetella bronchiseptica.a total of 53 isolates of bordetella bronchiseptica from dogs and pigs were tested for their ability to agglutinate chicken, horse, sheep, dog, pig, and guinea pig erythrocytes. no differences in hemagglutinating activity were attributed to the animal origin of the bordetella isolates. horse and dog erythrocytes consistently resulted in the strongest hemagglutination reactions, whereas only 4% of the b. bronchiseptica isolates produced weak agglutination of chicken erythrocytes. a total of 85% o ...19826125527
morphology of cells and hemagglutinogens of bordetella species: resolution of substructural units in fimbriae of bordetella pertussis.the morphology of cells and the hemagglutinogens isolated from cultures of bordetella pertussis, bordetella bronchiseptica, and bordetella parapertussis were studied by electron microscopy with the negative-staining technique. cells of all three species had long, thin (3 nm thick), peritrichously arranged fimbriae on the cell surface. similar structures were found in purified hemagglutinogen preparations together with shorter fimbrial structures 3 nm thick and from 40 to 100 nm long. in one expe ...19836137457
[a new method for the demonstration of the bordetella bronchiseptica capsule in electron microscopy].a new and rapid working method is presented for electronmicroscopic preparation of capsules from gram negative bacteria, e.g. bordetella bronchiseptica and pasteurella multocida. the advantage of the new technique is the availability of the results within 30 min after starting the preparation. the staining of the capsule by alcian blue has to be done as a first step together with glutaraldehyde fixation, before staining the bacterial cell with phosphotungstic acid. the new staining technic also ...19846202067
alkaline phosphatase activity in the turbinates of pigs infected with bordetella bronchiseptica. 19826218188
serologic survey for bordetella bronchiseptica in nebraska specific-pathogen-free pigs.the frequency of bordetella bronchiseptica infection in nebraska specific-pathogen-free (spf) pigs was determined by serologic and bacteriologic cultural analysis. serum samples from non-spf herds were tested for comparison. a total of 1,282 of 1,397 (92%) of the spf pigs tested had antibody to b bronchiseptica; 37 of 220 (17%) were culture-positive, and 67 of 4125 (1.6%) were considered suspicious for atrophic rhinitis during slaughter inspection. a higher percentage of the non-spf pigs had tit ...19836223547
some factors influencing the immunological adjuvant effect of bordetella bronchiseptica on the immune response to tetanus toxoid. 19836234765
field evaluation of an intranasally administered canine parainfluenza-bordetella bronchiseptica vaccine. 19806254224
phase-shift markers in bordetella: alterations in envelope proteins.envelope preparations derived from phase i strains of bordetella pertussis were shown to contain at least 10 major proteins or protein subunits. four of these proteins were either missing or produced in much lower concentrations in phase iv strains and in c-mode cells. envelope protein profiles of bordetella parapertussis were similar to those of b. pertussis except that more high-molecular-weight proteins were detected. phase i strains of bordetella bronchiseptica also had protein profiles simi ...19816263983
canine parainfluenza-bordetella bronchiseptica vaccine immunogenicity.the immunogenicity and safety of 3 serials of a canine parainfluenza (cpi) virus-bordetella bronchiseptica vaccine was evaluated. each serial was used to vaccinate 10 dogs with single doses given intranasally. the 30 vaccinated and 10 nonvaccinated controls dogs were challenge exposed with aerosols of virulent cpi virus and b bronchiseptica at 18 days and at 21 days, respectively, after vaccination. after challenge exposure, none of the 30 vaccinated dogs had clinical signs of disease; however, ...19816266289
intranasal vaccine trial for canine infectious tracheobronchitis (kennel cough).two field trials were conducted during periods of endemic (summer) and epizootic (winter) canine infectious tracheobronchitis activity to evaluate the efficacy of three intranasal vaccines in a closed commercial beagle breeding kennel. a trivalent vaccine containing bordetella bronchiseptica, canine parainfluenza, and canine adenovirus-2 was administered at 3 weeks of age. the vaccine was 71.2% and 81.8% effective in decreasing the incidence of coughing during the winter and summer trials, respe ...19816273648
canine infectious tracheobronchitis: effects of an intranasal live canine parainfluenza-bordetella bronchiseptica vaccine on viral shedding and clinical tracheobronchitis (kennel cough).a modified-live intranasal (in) canine parainfluenza (cpi)-virus bordetella bronchiseptica vaccine was evaluated in dogs for efficacy against laboratory-induced canine infectious tracheobronchitis. the comparative efficacies of in and parenteral administrations of the cpi virus fraction were also evaluated. the frequency and duration of clinical tracheobronchitis, blood serum agglutination titer, humoral antibody response, and duration of cpi virus and b bronchiseptica shedding were measured. gr ...19816275747
repression of adenylate cyclase in the genus bordetella.virulent phase i strains of bordetella pertussis synthesize the regulatory metabolite adenosine 3',5'-cyclic monophosphate (camp); whereas, non-virulent phase iv strains are unable to do so. these findings were confirmed and extended using additional strains of b. pertussis as well as strains of bordetella parapertussis and bordetella bronchiseptica. levels of adenylate cyclase activity and subsequent camp production were found to correlate. high adenylate cyclase activity during exponential pha ...19826287177
structure and biological properties of solubilized envelope proteins of bordetella pertussis.the structure and biological properties of solubilized envelope proteins of bordetella pertussis have been examined. several envelope proteins were found to be specific for phase i strains of b. pertussis and could be isolated by selective detergent extraction. these proteins had molecular weights of 90,000, 86,000, 81,000, 33,000, 31,000, and 30,000 and were reduced or absent in envelope preparations from bordetella bronchiseptica, bordetella parapertussis, or phase iv strains of b. pertussis. ...19836299946
synergistic effect of bordetella pertussis lymphocytosis-promoting factor on protective activities of isolated bordetella antigens in mice.the effect of low levels of added lymphocytosis-promoting factor (lpf) on the ability of several antigenic preparations isolated from bordetella pertussis and other bacteria to protect mice against intracerebral infection with b. pertussis was examined. lpf was found to enhance the protective activities of filamentous hemagglutinin, 22s antigen, and fimbriae isolated from b. pertussis. outer membrane protein preparations from phase i b. pertussis which had lpf removed by haptoglobin affinity col ...19836301999
immunoperoxidase study of canine distemper virus pneumonia.forty-two cases of canine pneumonia were examined for the presence of canine distemper virus. for that purpose canine distemper virus inclusion bodies were located. the histopathological lesions were related to the presence of canine distemper antigen, as demonstrated with an immunoperoxidase technique. this technique was more sensitive for detecting canine distemper infection in lung tissue than was the study of inclusion bodies. attention was also paid to combined infection with canine adenovi ...19836304834
ornithine-containing lipid of bordetella pertussis, a new type of hemagglutinin.the ornithine-containing lipids of six strains (phases i-iv) of bordetella pertussis were prepared from the total extractable cellular lipids by thin-layer chromatography and treatment with phospholipase a. they were compared with those prepared from two strains each of bordetella parapertussis and bordetella bronchiseptica. the structures of the ornithine-containing lipid of b. pertussis and the other two species were resolved by acid and alkaline hydrolysis, gas-liquid chromatography, infrared ...19836315433
species specificity of bordetella adherence to human and animal ciliated respiratory epithelial cells.bacteria of the genus bordetella adhere preferentially to ciliated respiratory epithelial cells. we investigated the specificity of this unique tropism by assessing the concentration-dependent adherence of the three bordetella species to ciliated cells from different hosts. bordetella pertussis and bordetella parapertussis adhere better to human ciliated cells than to those from rabbits, mice, or hamsters. in contrast, bordetella bronchiseptica demonstrates preferential adherence to nonhuman mam ...19836315583
studies on the immunological adjuvant activity of bordetella bronchiseptica in mice. 19836331140
alveolar lavage in dogs.alveolar lavage was performed in 10 healthy dogs. after tracheal intubation was done, a sterile fiberoptic bronchoscope was wedged in a distant bronchus and the lungs were lavaged with sterile saline solution. an average of 140 ml of saline solution was flushed into the lungs of each dog, and an average of 79% of the solution was recovered. examination of the recovered fluid revealed average total cell counts of 6.4 x 10(6) cells/dog. average differential cell counts were as follows: macrophages ...19836338775
[etiology of atrophic rhinitis (a.r.) in swine. 4. serological cross-test with 10 bordetella bronchiseptica strains and 161 field sera]. 19836352232
phenotypic variation and modulation in bordetella bronchiseptica.most of the isolates of bordetella bronchiseptica obtained by this laboratory possessed a characteristic colonial morphology when grown on bordet- gengou agar (bga) at 37 degrees c. the colonies appeared domed (dom+) with a smooth colonial surface (scs+) and a clear zone of hemolysis ( hly +). from these dom+ scs+ hly + bga colony types arose flat (dom-), smooth colonial surface (scs+) and nonhemolytic ( hly -) variants at frequencies of 10(-2) to 10(-3). isogenic pairs of dom+ scs+ hly + and do ...19846373614
[importance of precolostral inoculation of piglets with porcine enterovirus serotype 2 for the course of a postcolostral infection with bordetella bronchiseptica]. 19846376047
[nonfermenting gram-negative bacteria--bordetella bronchiseptica]. 19846377771
alveolar macrophage plasminogen activator.plasminogen activator is a neutral serine protease secreted by many different cells, including activated peritoneal macrophages, which can mediate both inflammation and fibrinolysis and perhaps cytolysis of tumor cells. secretion of plasminogen activator by rabbit alveolar macrophages derived from normal animals and rabbits pretreated with bacillus calmette-guérin (bcg) to activate these macrophages was examined. plasminogen activator was secreted into media of cultured alveolar macrophages, but ...19846378611
measurement of serum antibody in swine vaccinated with bordetella bronchiseptica: comparison of agglutination and enzyme-linked immunosorbent assay methods.the immune responses of 514 pigs from 5 swine breeds (chester white, duroc, hampshire, landrace, yorkshire) to vaccination with bordetella bronchiseptica were measured by agglutination and enzyme-linked immunosorbent assay (elisa) methods. both assays showed higher antibody levels in sera of pigs after vaccination than in sera of the pigs before vaccination. the variability of the responses among breeds was greater for the agglutination method than for the elisa method. the elisa proved to be mo ...19846395741
antibacterial activity of microbicidal cationic proteins 1 and 2, natural peptide antibiotics of rabbit lung macrophages.microbicidal cationic proteins 1 and 2, peptides derived from rabbit lung macrophages, were tested for bactericidal activity against various bacterial species. both were highly active against diverse gram-positive and gram-negative organisms under conditions of near-neutral ph (between 7 and 8) and relatively low ionic strength. susceptible species included staphylococcus aureus, staphylococcus epidermidis, streptococcus pneumoniae, listeria monocytogenes, pseudomonas aeruginosa, klebsiella pneu ...19836413408
pharmacological modulation of bronchial hyperreactivity.the airways of asthmatics are hyperreactive, not only to allergens but to a wide range of non-specific physical and chemical stimuli. four mechanisms which have been proposed to be causes of hyperreactivity are (i) a decrease in baseline airway calibre (ii) an increase in the responsiveness of the bronchial smooth muscle (iii) an imbalance in the autonomic neurophysiological regulation of airway calibre and (iv) epithelial changes which lead to an increase in the accessibility of allergens and n ...19836418560
a survey of the pathology of marmosets (callithrix jacchus) derived from a marmoset breeding unit.the results of a survey of the major pathological conditions encountered in an established breeding colony of common cotton-eared marmosets (callithrix jacchus) is presented. 265 home-bred and 70 imported wild-caught marmosets were examined. a heinz body haemolytic anaemia and skeletal muscle myopathy were the most common pathological findings and were considered to be a result of a complex nutritional deficiency involving vitamin e, selenium and protein. inflammatory disease of the intestinal t ...19836431178
an outbreak of bordetella bronchiseptica pneumonia in a colony of common marmosets (callithrix jacchus).an outbreak of bordetella bronchiseptica pneumonia occurred in a breeding colony of common marmosets (callithrix jacchus). 16 animals, all except one under 12 months of age, died suddenly. extensive lesions of pneumonia and pleurisy were found at necropsy and b. bronchiseptica was isolated from the nasopharynx, trachea and lungs. older animals had only a mild rhinitis. colonization of the nasal mucosa occurred in 71 of 156 marmosets.19836431182
adherence of bordetella bronchiseptica to hamster lung fibroblasts.the adherence of bordetella bronchiseptica smooth-, intermediate-, and rough-phase isolates to hamster lung fibroblasts (hlf) (don line) was characterized by competitive inhibition studies and enzyme and chemical treatments of both the bacteria and the hlf. the adherence of the rough- and intermediate-phase isolates (n = 13) was altered by coincubation of the bacteria and hlf with cationic chelators, including egta and citrate. egta inhibition of the adherence of the rough- and intermediate-phas ...19846437989
potentiation of an ige-like response to bordetella bronchiseptica in pigs following ascaris suum infection.ascaris suum-infected and uninfected pigs were vaccinated with bordetella bronchiseptica bacterin at 8 and 28 days of age. only the infected pigs gave type i cutaneous hypersensitivity to the bacterin when tested at 80 days of age. only the native sera of infected pigs caused passive cutaneous anaphylaxis 24 h after inoculation into guinea pigs. heating the sera at 56 degrees c for 4 h abolished this property. mice infected with a. suum for 34 days did not react to the bacterin. an a. suum infec ...19846440350
characterization of dermonecrotic toxin produced by serotype d strains of pasteurella multocida.dermonecrotic toxin (dnt) produced by serotype d strains of pasteurella multocida, isolated from pigs, was characterized and compared with dnt produced by bordetella bronchiseptica. the dnt prepared by sonication from p multocida or b bronchiseptica had dermonecrotic activity and lethal toxicity for guinea pigs and mice, and also induced marked atrophy of spleens in the mice. toxicity of p multocida or b bronchiseptica dnt was completely inactivated by heating at 70 c for 30 minutes, and was red ...19846441488
drug resistance and r plasmids in bordetella bronchiseptica isolates from pigs.a total of 207 strains of bordetella bronchiseptica isolated from pigs in 1978 and 1979 were tested for drug resistance and for the properties of their r plasmids. apart from intrinsic resistance to spectinomycin, single (sulfadimethoxine), double (sulfadimethoxine and streptomycin), andt riple (sulfadimethoxine, streptomycin, and ampicillin) resistance were found in 54.1%, 1.0%, and 15.9% of the strains, respectively. all of the triple-resistance determinants were associated with mercury resist ...19816457240
[detection of bordetella bronchiseptica strains containing the main agglutinogens of all species of the genus bordetella].the study of 26 b. bronchiseptica strains with typical morphological and biochemical properties resulted in the detection of 8 strains having the main specific agglutinogens of 3 bordetella species (serovars) in different combinations. the presence of the agglutinogens was confirmed in the agglutination test and the agglutinin adsorption test with the use of monospecific antisera to the main agglutinogens. the comparison of natural b. bronchiseptica serovars and artificial convertants (resulting ...19846464572
evaluation of the rapid nft system for identification of gram-negative, nonfermenting rods.this study evaluated the ability of the rapid nft system (api system sa, montalieu-vercieu, france) to accurately identify 262 clinically isolated, gram-negative, nonfermentative rods without additional tests. identifications were classified as correct; low discrimination, with a spectrum of two or more possibilities (additional tests necessary for accurate identification); and incorrect. correct identification rates were analyzed in two categories: (i) correct to species or biotype for all orga ...19846490857
immunogenicity and safety of an attenuated bordetella bronchiseptica vaccine in pigs.the immunogenicity and safety of an attenuated bordetella bronchiseptica vaccine for swine atrophic rhinitis (ar) was evaluated in 22 hysterectomy-produced, colostrum-deprived pigs and 18 conventional pigs. none of 8 pigs inoculated at 7 days of age intranasally with greater than or equal to 3 x 10(5) colony-forming units (cfu) of vaccinal strain/pig and 2 of 5 pigs inoculated at 7 days of age intranasally with 3 x 10(4) cfu of the vaccinal strain/pig developed ar after intranasal challenge expo ...19846497138
pneumonia and atrophic rhinitis in pigs from a test station--a follow-up study.pneumonia and atrophic rhinitis were studied for the second consecutive year in pigs at the same test station. pneumonia was found to reduce mean daily gain by 3.3% for every 10% of the pig's lungs that had lesions. atrophic rhinitis did not affect mean daily gain. there was no association between the development of atrophic rhinitis and the development of pneumonia. pigs that were vaccinated with a bordetella bronchiseptica bacterin did not have turbinate atrophy scores or mean daily gains diff ...19846511627
epidemiological study of pasteurella multocida and bordetella bronchiseptica in atrophic rhinitis.an epidemiological study of atrophic rhinitis was carried out in four pig herds. observations were made of (i) infection with bordetella bronchiseptica and pasteurella multocida, (ii) the presence of brachygnathia superior (bs score), (iii) the extent (grade) of turbinate atrophy and pneumonia at slaughter and (iv) growth rates from two to 16 weeks of age and average daily weight gains to slaughter. in two of the herds with no history of atrophic rhinitis, b bronchiseptica and non-toxigenic stra ...19846523700
[experimental studies of bordetella bronchiseptica infection in guinea pigs]. 19846529325
influence of vaccination of sows with bordetella-pasteurella vaccines on the occurrence of atrophic rhinitis among their offspring after experimental infection with bordetella bronchiseptica and toxigenic pasteurella multocida.experimental infections with bordetella bronchiseptica and a toxigenic strain of pasteurella multocida were carried out in newborn piglets from 25 sows. severe progressive atrophic rhinitis corresponding to the natural disease was produced. the effect of vaccination of sows during pregnancy with two vaccines containing antigens from b. bronchiseptica and toxigenic p. multocida on the incidence of nasal lesions in the offspring was studied.19846531207
biochemical and immunological analyses of the cell surface of bordetella bronchiseptica isolates with special reference to atrophic rhinitis in swine.the guinea-pig skintest was used to test the pathogenic character of nine bordetella bronchiseptica isolates derived from a number of different animals. one isolate was non-pathogenic, one showed a doubtful reaction whereas the others were pathogenic. analysis of the cell envelope protein patterns by sodium dodecyl sulphate polyacrylamide gel electrophoresis revealed only minor differences. two major protein bands and at least thirty five minor bands were observed. the major protein with an appa ...19846531966
[epizootiologic studies of rhinitis atrophicans in pigs. iii. studies of the properties of bordetella bronchiseptica exotoxin]. 19836613413
[epizootiologic studies of atrophic rhinitis of swine. iv. effect of the heat-labile toxin of bordetella bronchiseptica strains on the lymphatic organs of the mouse]. 19836659753
bordetella bronchiseptica bacteremia. 19846702200
[etiopathogenesis of bordetella bronchiseptica infection in swine]. 19846720171
[differentiation of bordetella bronchiseptica strains. 3. brief study of different reaction of various mouse lines to bordetella bronchiseptica strains]. 19846721637
effect of ph, temperature and media on acid and alkaline phosphatase activity in "clinical" and "nonclinical" isolates of bordetella bronchiseptica.twenty-two isolates of bordetella bronchiseptica were studied to determine the effects of ph, incubation temperature and type of media on peak acid and alkaline phosphatase activity. the ph optimum for alkaline phosphatase activity was 9.0 for all of the isolates tested. the ph optimum for acid phosphatase activity was 5.8 for 67% of the isolates and 4.8 for 33%. all of the isolates showed peak phosphatase activity at 37 degrees c. no preference was shown in 35% of the isolates between the types ...19846722645
comparative efficacy of sulfamethazine and sulfathiazole in feed for control of bordetella bronchiseptica infection in swine.seventy-two conventionally raised pigs were challenge exposed intranasally when approximately 3.5 weeks old with yolk-grown bordetella bronchiseptica. twenty-four pigs acted as noninfected, nonmedicated controls. feed containing sulfamethazine or sulfathiazole (110 mg/kg of feed) was initiated in 2 groups of 24 infected pigs each 3 days after challenge exposure and was fed continuously for 56 days. twenty-four infected pigs were given nonmedicated feed. challenge exposure with the b bronchisepti ...19846731985
purification and antibacterial activity of antimicrobial peptides of rabbit granulocytes.six antimicrobial peptides, corresponding to the family of "lysosomal cationic proteins" described previously by zeya and spitznagel (h. i. zeya and j. k. spitznagel, j. bacteriol. 91:750-754, 1966; h. i. zeya and j. k. spitznagel, j. bacteriol. 91:755-762, 1966), were purified from rabbit peritoneal granulocytes by preparative acrylamide gel electrophoresis and reversed-phase high-pressure liquid chromatography. each of the peptides was of low molecular weight (ca. 4,000) as determined by sodiu ...19846735465
effect of various oral dose levels of a trimethoprim/sulphadiazine mixture on bordetella bronchiseptica infection and on the proliferation of trimethoprim-resistant faecal coliforms in pigs.when a 1:5 mixture of trimethoprim (tmp) and sulphadiazine was fed to pigs intra-nasally infected with bordetella bronchiseptica, 10 mg/kg/day was shown to be highly effective in suppressing the organism. this dose level had little effect on numbers of tmp-resistant coliforms in faeces, but oral doses of 30 mg/kg/day eventually selected a resistant population. it is suggested that the proliferation of resistant coliforms would be minimized by administration of the lowest oral dose rates of antib ...19836822727
comparison of an infective avirulent and canine virulent bordetella bronchiseptica.two bordetella bronchiseptica isolates, s-55 and d-2, were evaluated in dogs for inducement of (i) infection, (ii) clinical bordetellosis, and (iii) histopathologic changes on tracheal and bronchiole tissues. further, each isolate was characterized for variance in (i) toxicity for mice and (ii) intracellular proteins. both s-55 and d-2 were detectable in test dog groups during the 26-day test period, although 545 times more d-2 was recovered than was s-55. in dogs inoculated with d-2, clinical i ...19836830009
an acid phosphatase activity in isolates of bordetella bronchiseptica.a simple qualitative test was used to investigate acid phosphatase activity in isolates of bordetella bronchiseptica from different animal species. of the 78 isolates examined, 58 showed the enzyme activity in less than 12 hours of incubation at 37 degrees c.19836831310
susceptibility of bordetella species to growth inhibition and killing by chlorpromazine.chlorpromazine, the prototype phenothiazine tranquilizer, inhibited the growth and killed organisms of the genus bordetella. there were striking differences, however, among the three bordetella species. bordetella pertussis was most susceptible, with some inhibition of growth at greater than or equal to 4 micrograms/ml and killing at 16 micrograms of chlorpromazine per ml. bordetella parapertussis and bordetella bronchiseptica were less susceptible, with killing at 32 and 256 micrograms/ml, resp ...19836838185
differentiation among bacteria isolated from turkeys with coryza (rhinotracheitis).gram-negative bacteria isolated from turkeys with coryza in the united states, the federal republic of germany, and the republic of south africa were compared with known alcaligenes species and bordetella bronchiseptica. the turkey isolates were separated into three distinct groups based on biochemical and physiologic tests. forty of the 68 isolates studied (group i) were different from alcaligenes sp. and b. bronchiseptica. isolates in group i produced a heat-labile hemagglutinin and did not gr ...19836870724
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