| the opsonic activity of stored blood. | experiments were performed to measure the stability of opsonins during storage of whole blood collected in cpd solution and stored at 4 c. three units were collected, and aliquots removed and recalcified on days 0, 3, 7, 14, 21, and 28. reconstituted serum was immediately frozen and stored at -70 c. the ability to opsonize escherichia coli 075 and pseudomonas aeruginosa immunotype 1, both of which require activation and utilization of the alternative pathway of complement for opsonization, were ... | 1977 | 405758 |
| [in vitro effects of the combination of carbenicillin with gentamicin or tobramycin with respect to pseudomonas aeruginosa]. | | 1977 | 405784 |
| cell-mediated immune responses to pseudomonas aeruginosa. | of six healthy laboratory workers with no history of illness caused by pseudomonas aeruginosa, four exhibited positive skin responses at 24 hours, strong inhibition of leukocyte migration, and marked stimulation of blastogenesis of peripheral lymphocytes when exposed to a "cocktail" of three phenol-killed strains of p aeruginosa. there was no correlation between the extent of these responses with serum hemagglutinin titers. it is postulated that cell-mediated immunity against p aeruginosa may ha ... | 1977 | 405880 |
| [virulence of human and environmental strains of "pseudomonas aeruginosa" in mice (author's transl)]. | the virulence of 21 clinical isolates and 10 environmental strains of pseudomonas aeruginosa was studied by intraperitoneal challenge in mice. the ld50 values of human strains ranged from 10(7),(0) to 10(8),(5) viable cells per mouse (average: 10(7),(7)(2)). the ld50 of environmental strains ranged from 10(7),(2) to 10(8),(1) (average: 10(7),(59)). these results are not significantly different. experimental virulence for mice of p. aeruginosa strains found in hospital environment allows no predi ... | 1977 | 405899 |
| linkage of mercury, cadmium, and arsenate and drug resistance in clinical isolates of pseudomonas aeruginosa. | of the 787 isolates, 99.8% were metal resistant, with most (99.5%) showing multiple resistance. fifty-three percent of the isolates were both metal and drug resistant, whereas only 19% were metal resistant and drug sensitive. | 1977 | 405928 |
| allantoinase and allantoicase synthesis in pseudomonas aerguinosa. | allantoinase (allantoin amidohydrolase, ec 3.5.2.5.) and allanoicase (allantoate amidinohydrolase, ec 3.5.3.4) of pseudomonas aeruginosa are inducible enzymes, whose syntheses are enhanced by the presence of allantoin, allantoate, ureidoglycolate, n-carbamoyl-l-asparagine, n-carbamoyl-l-aspartate, hydantoate, and diureidomethane. for each compound a specific ratio between the activities of allantoinase and allantoicase was obtained. the synthesis of these enzymes is not coordinately controlled. ... | 1977 | 406022 |
| the nature of pseudomonas aeruginosa strain pao bacteriophage receptors. | receptors for phages specific to pseudomonas aeruginosa strain pao were studied. phages 16, 44, 109, f8, and pbi are lipopolysaccharide (lps) specific as shown by neutralization tests. the phi50's of the lps, adsorption rate constants with strain pao and the plaque morphologies of these five phages were quite similar. phages 1214 and 7 also appear to be lps-specific on the basis of host-range studies. phage 73 is pilus-specific, while phages 21 and 68 fall into a group which does not attach to p ... | 1977 | 406024 |
| the orthonitrophenyl-beta-d-galactoside hydrolase from pseudomonas aeruginosa (0: 11 serotypes) is a superficial enzyme. | about 95% fo the 0: 11 strains of pseudomonas aeruginosa was able to hydrolyze orthonitrophenyl-beta-d-galactopyranoside (onpg), but was unable to use lactose. the onpg-hydrolyzing enzyme was located essentially in the periplasm, as seen by biochemical and ultrastructural studies. | 1977 | 406028 |
| experimental pulmonary infection of mice by tracheal intubation of pseudomonas aeruginosa: the use of antineoplastic agents to overcome natural resistance. | tracheal intubation of viable pseudomonas aeruginosa atcc 19660 into the lungs of mice had no significant effect on the animals even with administration of organisms as high as 5.0 x 10(9) cfu. animals treated with a single injection of an antineoplastic drug were, however, susceptible to bacterial challenge into the lungs. ld50 values of 4.1 x 10(7), 4.8 x 10(7), and 1.0 x 10(8) cfu were obtained when animals were simultaneously infected and treated with methotrexate, vincristine sulfate, or cy ... | 1977 | 406029 |
| clinical and laboratory study of tobramycin in the treatment of infections due to gram-negative organisms. | tobramycin, an aminoglycoside antibiotic, was used to treat 52 infections due to gram-negative organisms in 51 patients. complicated urinary tract infections, bacteremia and pyelonephritis accounted for 80% of the infections. the rate of immediate satisfactory response was 79%. during therapy with tobramycin, resistant organisms emerged in four patients--two pseudomonas aeruginosa and two escherichia coli strains. there were four superinfections with tobramycin-resistant providencia sp. in four ... | 1977 | 406032 |
| superinfection inhibition by prophage b3 of some r plasmids in pseudomonas aeruginosa. | | 1977 | 406164 |
| binding of progesterone to neisseria gonorrhoeae and other gram-negative bacteria. | the binding of [1,2-(3)h]progesterone to progesterone-sensitive neisseria gonorrhoeae cs-7 and the progesterone-insensitive neisseria mucosa, pseudomonas aeruginosa, and salmonella typhimurium (rough and smooth strains) was investigated. the kinetics of binding to n. gonorrhoeae cs-7 demonstrated that the majority of the progesterone binding occurred and equilibrium was reached within the first 30 min. despite the rapid binding of progesterone, only about 20% of the added steroid was bound at th ... | 1977 | 406199 |
| structure-activity relationships of an exotoxin of pseudomonas aeruginosa. | the relation of the structure of pseudomonas aeruginosa exotoxin a (pa toxin) to its enzymatic activity (adenosine 5'-diphosphate-ribosyl transferase) in vitro and to its toxicity in vivo was examined. pa toxin is produced as a single polypeptide chain with a molecular weight of about 71,500. pa toxin is produced by pseudomonas as a toxic proenzyme that lacks enzymatic activity. adenosine 5'-diphosphate-ribosyl transferase activity is expressed when the molecule is denatured and reduced or when ... | 1977 | 406204 |
| composition and molecular weight of pili purified from pseudomonas aeruginosa k. | pseudomonas aeruginosa strain k (pak) bears polar pili that promote infection by at least six bacteriophages. moreover, a recently isolated mutant of strain k (pak/2pfs) is many times more piliated than the wild-type strain and facilitates the preparation of large amounts of pure pili for biochemical studies. the present investigation was carried out to establish the structural relatedness of pak and pak/2pfs pili and to determine their biochemical composition. a purfication procedure is describ ... | 1977 | 406258 |
| transfer and expression of pseudomonas plasmid rp1 in caulobacter. | this study demonstrates that the host range of pseudomonas plasmid rp1 includes the genus caulobacter. caulobacter was shown to acquire three antibiotic resistance markers located in rp1. a fourth plasmid marker, susceptibility to an rna bacteriophage, was not expressed, but could be transferred from caulobacter to escherichia coli. the lack of phenotypic expression of the phage marker was manifested by the inability of the phage to adsorb or to produce plaques on caulobacter transcipients. mati ... | 1977 | 406354 |
| prophage f116: evidence for extrachromosomal location in pseudomonas aeruginosa strain pao. | f116 is a temperate-generalized transducing phage of pseudomonas aeruginosa. genetic evidence leads to the conclusion that f116 prophage dna is maintained extrachromosomally as a plasmid. preliminary physical evidence is presented to support this hypothesis. | 1977 | 406425 |
| [morphology of pseudomonas aeruginosa altered by antibiotic effect of sulbenicillin]. | | 1977 | 406433 |
| [fluorescence serological differentiation between somatic and flagellar antigens of pseudomonas aeruginosa]. | | 1977 | 406743 |
| cardiorespiratory effects of pseudomonas and e. coli endotoxins in the awake dog. | a comparison of the cardiovascular and respiratory effects of pseudomonas aeruginosa and escherichia coli endotoxins was investigated in the unanesthetized dog. animals were anesthetized with halothane for placement of cardiovascular catheters and then allowed to awaken prior to collection of control data and experimentation. one group of 12 animals was given e. coli endotoxin (5 mg/kg), another group of 13 received pseudomonas endotoxin (8 mg/kg). variables were collected for 6 h after endotoxi ... | 1977 | 406796 |
| beta-lactamases produced by a pseudomonas aeruginosa strain highly resistant to carbenicillin. | a pseudomonas aeruginosa strain isolated at besançon hospital, france, proved to be highly resistant to carbenicillin and showed a high hydrolytic activity toward this antibiotic. we clearly demonstrated that two beta-lactamases were synthetized: one of them, constitutive, has its enzymatic activity directed mainly toward penicillins, and carbenicillin appears to be its best substrate (higher v(max)); thus, this beta-lactamase is a "carbenicillinase" that differs from the well-known "tem-like" e ... | 1977 | 406828 |
| bactericidal activity of macromomycin, a antitumor antibiotic. | susceptibility testing by the broth dilution method showed that all the gram-positive but only some of the gram-negative bacteria tested were susceptible to the antitumor antibiotic, macromomycin (mcr; nsc 170105). the minimal inhibitory concentration for the susceptible organisms was less than 3 mug/ml. the action of mcr was bactericidal; however, at very high concentrations (50 mug/ml and above) some organisms occasionally escaped death. none of the escaped organisms was resistant to mcr. in c ... | 1977 | 406834 |
| five-hour minimal inhibitory concentration test of four antimicrobial agents for pseudomonas aeruginosa. | a rapid 5-h minimal inhibitory concentration procedure and a minimal bactericidal concentration procedure are described for testing pseudomonas aeruginosa against gentamicin, tobramycin, amikacin, and carbenicillin. the rapid test results were demonstrated to correlate with the conventional tube dilution procedure. | 1977 | 406835 |
| synergy between ticarcillin and tobramycin against pseudomonas aeruginosa and enterobacteriaceae in vitro and in vivo. | the antibacterial activities of ticarcillin, carbenicillin, tobramycin, and gentamicin and of combinations of these antibiotics were measured against pseudomonas aeruginosa and other gram-negative bacilli in vitro and in experimental mouse infections. synergistic effects were produced by the penicillin/aminoglycoside combinations in growth inhibition tests and in bactericidal tests against many of the bacteria tested. combinations of ticarcillin + tobramycin were more active in vitro than carben ... | 1977 | 406837 |
| pseudomonal balanitis. | significant ecologic changes in the cutaneous flora during treatment may present a challenge both diagnostically and therapeutically. the development of an erosive balanitis due to pseudomonas aeruginosa presented an example of such a microbiologic shift in the case reported. the eruption developed during treatment with topical antibacterial, antifungal, and corticosteroid agents. the sudden exacerbation of any balanitis while under treatment should alert the physician to the possibility of supe ... | 1977 | 406856 |
| nuclear magnetic resonance study of exchangeable and nonexchangeable protons in azurin from pseudomonas aeruginosa. | | 1977 | 406912 |
| the characterisation of inducible dehydrogenases specific for the oxidation of d-alanine, allohydroxy-d-proline, choline and sarcosine as peripheral membrane proteins in pseudomonas aeruginosa. | | 1977 | 406917 |
| characterization of 2-amino-2,6-dideoxy-d-glucose as a constituent of the lipopolysaccharide antigen of pseudomonas aeruginosa immunotype 4. | the title lipopolysaccharide was freed from its lipid a component by mild, acid hydrolysis, to give a polysaccharide fraction that was subsequently hydrolyzed completely to afford a mixture of neutral sugars and amino sugars. the amino sugars were separated, and identified as 2-amino-2-deoxy-d-galactose, 2-amino-2,6-dideoxy-galactose as a 2:1 mixture of the d and l enantiomers, and 2-amino-2,6-dideoxy-d-glucose. a reference sample of 2-amino-2,6-dideoxy-d-glucose was synthesized by an improved p ... | 1977 | 406998 |
| [metabolic and antigenic study of 430 strains of pseudomonas aeruginosa isolated in dakar. high frequency of serotype 0:11, beta-galactosidase positive biotype]. | | 1977 | 407014 |
| immunization with r mutants of salmonella minnesota. ii. comparison of the protective effect of immunization with lipid a and the re mutant. | the protective effect of active immunization with salmonella minnesota re bacilli or lipid a was assessed in the granulocytopenic rabbit model. animals were immunized with re bacilli, lipid a, or pseudomonas aeruginosa as a nonspecific immunogen. after colonization with one of three enterobacterial strains (two escherichia coli, one enterobacter aerogenes), the immunized rabbits as well as controls given saline injections were made leukopenic with nitrogen mustard and monitored for fever, bacter ... | 1977 | 407161 |
| transfer of chromosomal genes mediated by plasmid r68.45 in rhodopseudomonas sphaeroides. | plasmid r68.45 was transferred from pseudomonas aeruginosa pao25 to the photosynthetic species rhodopseudomonas gelatinosa and rhodopseudomonas sphaeroides by selection for resistance to antibiotics. r. sphaeroides strains carrying the plasmid could transfer the plasmid and also chromosomal genes to other strains of r. sphaeroides. | 1977 | 407213 |
| purification and properties of the periplasmic glucose-binding protein of pseudomonas aeruginosa. | a glucose-binding glycoprotein (gbp) from the periplasm of pseudomonas aeruginosa was purified to homogeneity as judged by polyacrylamide gel electrophoresis, molecular sieve chromatography, and double-diffusion gel precipitation. it had an average molecular weight of 44,500 and an isoelectric point of 4.7. one mole of glucose was bound per mole of gbp with a dissociation constant of 0.35 mum. the binding of radioactive glucose by gbp was not significantly inhibited by 10-fold-higher concentrati ... | 1977 | 407216 |
| dual enzymatic routes to l-tyrosine and l-phenylalanine via pretyrosine in pseudomonas aeruginosa. | | 1977 | 407230 |
| serological typing of pseudomonas aeruginosa: use of commercial antisera and live antigens. | a practical slide agglutination test, with commercial antisera (difco) and live antigens (antigens of live bacteria) taken directly from 24-h antimicrobial susceptibility plates, has been established for serotyping pseudomonas aeruginosa. until recently, the lack of both a standard antigenic scheme and a source of commercial antisera has made serological typing of this organism impractical. a simplified procedure with 17 unabsorbed antisera and live antigens prepared from materials readily avail ... | 1977 | 407246 |
| serum antibody to pseudomonas aeruginosa exotoxin measured by a passive hemagglutination assay. | a passive hemagglutination (pha) assay for antibody to pseudomonas aeruginosa exotoxin is described which utilizes chromic chloride-treated ovine erythrocytes coated with purified toxin. pha antitoxin titers correlated well with those obtained by a cytotoxicity neutralization assay (r = 0.91, p less than 0.001), whereas the pha assay was four to eight times as sensitive. the mean serum pha titer of 16 patients convalescing from recent pseudomonas infections (log2 = 9.4 +/- 3.9) was significantly ... | 1977 | 407250 |
| [inhibitor analysis of the electron transport chain of pseudomonas aeruginosa bacteria]. | | 1977 | 407272 |
| water beds - a potential source of pseudomonas aeruginosa. | water beds in use in this hospital were found to be contaminated with pseudomonas aeruginosa. the addition of sodium hypochlorite, giving a final concentration of 200 parts/10(6) available chlorine, was found to be effective in preventing microbial contamination over a 6-month study period. | 1977 | 407297 |
| detection of igg antibodies to type-specific pseudomonas aeruginosa lipopolysaccharides by solid-phase radioimmunoassay. | previous studies have suggested that igg serotype-specific antibodies are protective against infections with pseudomonas aeruginosa. in the present study, type-specific igg antibodies to p. aeruginosa were detected by solid-phase radioimmunoassay in sera from 15 volunteers before and after vaccination with lipopolysaccharides from p. aeruginosa and from four patients with endocarditis due to p. aeruginosa. significant type-specific increases in igg antibody occurred after both vaccination and in ... | 1977 | 407310 |
| [bacteriocin-like substances produced by pseudomonas aeruginosa]. | cultures of pseudomonas aeruginosa were tested for the production of bacteriocin-like substances, and differentiated with respect to three various indicator cultures. a technique was elaborated for the isolation of bacteriocin-like substances from a solid medium. physico-chemical properties of ps. aeruginosa were studied for the strains 8-h-3, pao-406, and pat-2. the molecular weight of bacteriocin-like substances was calculated for the strain 8-h-3. | 1977 | 407426 |
| vertebral osteomyelitis due to pseudomonas aeruginosa. | a case of vertebral osteomyelitis due to pseudomonas aeruginosa is described and the problems of diagnosis and treatment discussed. | 1977 | 407560 |
| [spondylitis caused by pseudomonas pyocyanea (pseudomonas aeruginosa)]. | | 1977 | 407647 |
| antibiotic resistance transfer from nonpathogenic to pathogenic bacteria. | alcaligenes species is a common contaminant of "wet" environmental areas on the surgical ward. although thought to be a nonpathogenic organism, recent clinical experience on the burn and trauma service has led us to believe that antibiotic resistance transfer may occur between alcaligenes and pseudomonas aeruginosa. to evaluate this possibility, germ-free mice were contaminated with alcaligenes species, which quickly established in the animals' gastrointestinal tracts. these animals then were bu ... | 1977 | 407662 |
| effect of aerosol immunization with re 595 salmonella minnesota on lung bactericidal activity against serratia marcescens, enterobacter cloacae, and pseudomonas aeruginosa. | intrapulmonary bactericidal activity was measured after mice were given 3 weekly aerosol exposures to acid-hydrolyzed re 595 salmonella minnesota. ten days after their last immunization, mice were challenged with aerolized serratia marcescens, enterobacter cloacae, or pseudomonas aeruginosa. quantitative bacterial counts in ground lung were obtained immediately after exposure and again 4 hours later. enhanced bactericidal activity against serratia marcescens and enterobacter cloacae was seen in ... | 1977 | 407823 |
| malignant external otitis: further considerations. | malignant external otitis is an infection which begins in the external auditory canal. it is uniformly caused by the gram negative pseudomonas aeruginosa organism and mainly affects elderly diabetics. it spreads to the soft tissues beneath the temporal bone and, if not properly treated leads to facial nerve palsy, mastoiditis, sepsis, osteomyelitis of the base of the skull, sigmoid sinus thrombosis, multiple cranial nerve palsies and death. experience with 72 patients in varying stages of the di ... | 1977 | 407826 |
| a unique nitric oxide-binding complex formed by denitrifying pseudomonas aeruginosa. | | 1977 | 407906 |
| purine degradation in pseudomonas aeruginosa and pseudomonas testosteroni. | 1. adenine, hypoxanthine, xanthine and guanine are broken down in pseudomonas aeruginosa and pseudomonas testosteroni to allantoin by the concerted action of the enzymes adenine deaminase, guanine deaminase, nad+-dependent xanthine dehydrogenase and uricase. 2. uric acid is broken down by an unstable, membrane-bound uricase with an unusually low ph optimum. 3. in both strains adenine inhibits growth and xanthine dehydrogenase. a second type of inhibition is manifest only in ps. testosteroni and ... | 1977 | 407941 |
| immunochemical studies on acetylornithine 5-aminotransferase from pseudomonas aeruginosa. | mouse antibodies with specificity towards acetylornithine 5-aminotransferase (acoat) from pseudomonas aeruginosa were used to study the structural similarities of several isofunctional enzymes from different sources. with the antibody directed against acoat, the amounts of enzyme present in cells grown under different conditions were determined. these experiments established that the enzyme is induced by arginine and is subject to repression by carbon sources. | 1977 | 408176 |
| activation of complement by opportunist pathogens and chemotypes of salmonella minnesota. | washed cells of staphylococcus aureus, escherichia coli, proteus mirabilis, pseudomonas aeruginosa, and salmonella minnesota chemotypes (s, rb, and re) were tested for their ability to activate the alternative complement pathway (acp). parameters of acp activation were (i) conversion of c3 in 10 mm ethyleneglycol-bis-(beta-aminoethyl ether)-n,n1-tetraacetic acid-treated human serum supplemented with 2.5 mm mgcl2, (ii) lysis of glutathione-treated human erythrocytes in the presence of human serum ... | 1977 | 408268 |
| in vitro studies with mecillinam on escherichia coli and pseudomonas aeruginosa. | the ability of a beta-lactam antibiotic to inhibit the growth of gram-negative bacteria depends on three main properties: ting sites in the bacterial cell; the ability to penetrate through the outer layers of the bacterial envelope to these sites; and the ability to resist destruction by beta-lactamases that may be encountered on the way to the target. this article describes the properties of mecillinam with respect to the last two of these properties. although able to hydrolyse mecillinam under ... | 1977 | 408322 |
| inhibition and facilitation of transfer among pseudomonas aeruginos r plasmids. | esamining 12 plasmids in pseudomonas aeruginosa, we found two types of interaction in their transfer (inhibition and facilitation), using donor cells carrying two compatible plasmids. (i) ten plasmids representing incompatibility groups p-1, p-2, p-5, p-6, and p-7 were all transmissible at a high frequency, 10-2 to 10-1, except for one with a lower frequency of about 10-3. the transfer of p-5 plasmids was inhibited by p-2 plasmids reciprocally or unilaterally, and the unilateral transfer inhibit ... | 1977 | 408326 |
| otitis externa due to pseudomonas in swimming pool bathers. | an outbreak of otitis externa was observed to affect one third of 230 swimmers using a new swimming pool within three weeks of its opening. pseudomonas aeruginosa was grown from the water and from all of the nine swabs taken from the infected ears of the swimmers. during the same period only six other cases of otitis externa were seen in the local general practice serving 4,000 patients. the disinfection procedures were found to be defective and after they were corrected the outbreak subsided. | 1977 | 408486 |
| sensitivity of pseudomonas aeruginosa to sulphonamides and trimethoprim and the activity of the combination trimethoprim: sulphamethoxazole. | the activities of three sulphonamides and trimethoprim against strains of pseudomonas aeruginosa have been studied. sulphadiazine had most activity, sulphadimidine had little, and the activity of sulphamethoxazole was intermediate. according to their sensitivity to sulphamethoxazole, strains were divided into two groups: "highly resistant" (16%, mic greater than 1000 microgram per ml) and "moderately resistant" (84%, mic less than or equal to 1000 microgram per ml). the former were resistant on ... | 1977 | 408490 |
| identification of the cell wall receptor for bacteriophage e79 in pseudomonas aeruginosa strain pao. | bacteriophage e79 was shown to interact with the lipopolysaccharide (lps) of pseudomonas aeruginosa strain pao. lps isolated from an e79-sensitive, smooth strain inactivated the phage, exhibiting a phl50 value (concentration of lps that caused a 50% decrease in the titer of phage during 1 h of incubation at 37 degrees c) of 0.04 microgram/ml, whereas the lps isolated from a rough mutant derived from the wild type showed no neutralizing activity towards e79. edta and sodium deoxycholate were demo ... | 1977 | 408513 |
| [cytotoxicity of pseudomonas aeruginosa to peritoneal phagocytes of the guinea pig]. | | 1977 | 408534 |
| isolates of pseudomonas aeruginosa from australian hospitals having r-plasmid determined antibiotic resistance. | six hundred and fifty hospital isolates of pseudomonas aeruginosa from australian sources have been examined for high-level resistance to a number of antibiotics. fifty-four strains were resistant to one or more of the antibiotics, and four of these strains carried as r-plasmid conferring resistance to streptomycin, tetracycline and sulphanilamide, and belonging to incompatibility group p-2. possible reasons for the low incidence of r-plasmids in p. aeruginosa from australian sources are discuss ... | 1977 | 408596 |
| the genetic organization of arginine biosynthesis in pseudomonas aeruginosa. | six loci coding for arginine biosynthetic enzymes in pseudomonas aeruginosa strain pao were identified by enzyme assay: arga (n-acetylglutamate synthase), argb (n-acetylglutamate 5-phosphotransferase), argc (n-acetylglutamate 5-semialdehyde dehydrogenase), argf (anabolic ornithine carbamoyl-transferase), argg (argininosuccinate synthetase), and argh (argininosuccinase). one-step mutants which had a requirement for arginine and uracil were defective in carbamoylphosphate synthase, specified by a ... | 1977 | 408599 |
| amikacin therapy of exacerbations of pseudomonas aeruginosa infections in patients with cystic fibrosis. | amikacin, a new semisynthetic aminoglycoside antibiotic with activity against pseudomonas aeruginosa, was used to treat 22 acute exacerbations of chronic pulmonary infections in 18 patients with cystic fibrosis. patients ranged from 5 to 32 years of age and had mucoid p. aeruginosa isolated from sputum. the amikacin dose was usually 7.5 mg/kg every eight hours but was increased to 10 mg/kg and/or carbenicillin was added in selected cases depending on clinical course. although p. aeruginosa was n ... | 1977 | 408787 |
| [characterizations of pseudomonas aeruginosa species by pyocine typing methods (author's transl)]. | | 1977 | 408888 |
| aeromonas hydrophila septicaemia producing ecthyma gangrenosum in a child with leukaemia. | a 4-year-old girl with leukaemia developed fever and ecthyma gangrenosum. aeromonas hydrophila was isolated from blood and skin lesions. ecthyma gangrenosum is often considered pathognomonic of pseudomonas aeruginosa septicaemia. as is evident from the case reported, it may also result from infection with a. hydrophila, which has different antibiotic sensitivities, and which is now being recognised more frequently as a serious pathogen in immunosuppressed patients. | 1977 | 408919 |
| [pseudomonas aeruginosa in sewage and surface water (author's transl)]. | | 1977 | 409455 |
| mannose-binding hemagglutinins in extracts of pseudomonas aeruginosa. | mannose-binding hemagglutinins were found in the extracts of a pyocyanin-forming pseudomonas aeruginosa, which contain galactose-specific hemagglutinins. they were purified simultaneously with the latter proteins by heating to 70 degrees c, precipitating with ammonium sulfate, application to a sepharose 4b column, and elution from it by 0.05 m mannose. the mannose-specific hemagglutinins were shown to be similar to the galactophilic ones in (a) being glycoproteins of very low molecular weight (a ... | 1977 | 409463 |
| antibacterial activity of ticarcillin, tobramycin and gentamicin alone and in combination against pseudomonas aeruginosa in vitro. | using the biophotometer with ticarcillin no persistent bactericidal effect was found against pseudomonas aeruginosa nctc 10490. after addition of 1.2 microgram/ml gentamicin an increase of multiplication of bacteria was observed, but not after 1.2 microgram/ml tobramycin. with 6.2 microgram/ml tobramycin bactericidal effects lasted more than 24 h. in tube dilution test with isotonic sensi-test broth out of 109 examined strains 51% were resistant to gentamicin, 16% to tobramycin and 4.5% to ticar ... | 1977 | 409590 |
| bacterial adherence to nasal mucosal cells. | the ability of several bacterial species to adhere to human nasal mucosal cells and their distribution on nasal mucosal surfaces was studied. staphylococcus aureus, staphylococcus epidermidis, streptococcus pyogenes, and pseudomonas aeruginosa adhered to scraped nasal mucosal cells. in contrast, viridans streptococci and klebsiella pneumoniae exhibited feeble or no adherence to nasal mucosal cells. s. aureus affinity for the nasal mucosal cells of carriers of s. aureus was greater than for those ... | 1977 | 409676 |
| kanamycin-resistance mechanism of pseudomonas aeruginosa governed by an r-plasmid independently of inactivating enzymes. | | 1977 | 409703 |
| patterns and mechanisms of emergence of resistance to amikacin. | emergence of gram-negative bacilli resistant to amikacin occurred in five of 96 patients treated. three of the five instances were associated with clinical failure and arose during therapy for an infection caused by a pathogen also susceptible to gentamicin. the other two episodes were associated with colonization. the enzyme aminoglycoside-6'-acetyltransferase, which inactivates amikacin, was found in serratia marcescens. decreased permeability to amikacin was shown in four isolates of pseudomo ... | 1977 | 409785 |
| experimental studies on the pathogenesis of infections due to pseudomonas aeruginosa: direct evidence for toxin production during pseudomonas infection of burned skin tissues. | direct evidence is presented for the production of an exotoxin by pseudomonas aeruginosa multiplying at the burned site in an infected mouse. pseudomonas toxin was assayed by measurement of its ability to catalyze the transfer of radioactivity from [14c]adenine-labeled nicotinamide adenine dinucleotide to elongation factor 2 (adenosine diphosphate ribosylation activity). this enzyme activity was found in saline extracts of burned infected skin but was not present in similar extracts of burned un ... | 1977 | 409788 |
| effect of colloidal association on the measured activity of alkylbenzyldimethylammonium chlorides against pseudomonas aeruginosa. | the antibacterial activities of a homologous series (c8-c18) of alkylbenzyldimethylammonium cholorides (abdac) against pseudomonas aeruginosa have been measured using both a minimum inhibitory concentration (mic) procedure and a sterilization kinetics test carried out in deionized water. there was a log-linear relationship between activity measured by kinetics and carbon number. with mic there was a log-linear relationship up to c14, when there was a turndown in activity. consideration of the co ... | 1977 | 409841 |
| secondary structure of rna from bacteriophages f2 qbeta, and pp7. | electron microscopy of rna-protein monolayers prepared under partial denaturing conditions has been used to compare the secondary structure of coliphage f2 and qbeta and pseudomonas aeruginosa phage pp7 rnas. the secondary structure map of f2 rna contains a central open loop and four symmetrically placed hairpins, which is similar to the pattern reported by jacobson (a. b. jacobson, proc. natl. acad. sci. u.s.a. 73:307-311, 1976) for the closely related phage ms2. with the same denaturing condit ... | 1977 | 409852 |
| septicaemia in the tropics. a prospective epidemiological study of 146 patients with a high case fatality rate. | a prospective study showed that during the first 6 months of 1976, 146 patients out of a total of 3938 admitted to a hospital in nigeria were suffering from septicaemia, or developed the condition while in hospital. findings differed from those reported from developed countries in that the majority of infections were community acquired, those most frequently and severely affected were the very young, and salmonella spp. and staphylococcus aureus were the most important pathogens. however, other ... | 1977 | 410093 |
| successful treatment of pseudomonas aeruginosa--ventriculitis with intraventricular gentamicin in a child with hydrocephalus. | a hydrocephalic child, who was operated with a ventriculo-peritoneal shunt at the age of 1 month, developed ventriculitis due to pseudomonas aeruginosa at 8 months. after removal of the shunt and successively increasing intramuscular and intraventricular doses of gentamicin the patient was cured and a new shunt could be inserted. as high 24-hour gentamicin level in the cerebrospinal fluid as 76 microgram/ml was reached without any apparent toxic signs. | 1977 | 410097 |
| comparative study of chromogenesis and endotoxin production from pathogenic pseudomonas aeruginosa strains, isolated from neoplastic processes. | several differences in relation to the chromogenesis and the production of endotoxins were found in ps. aeruginosa strains, isolated from tumors. the strains isolated from neoplastic processes showed a higher amount of chromogenic fractions as compared with the control strains. phenazinic compounds presented the main differences. using two common methods of isolation and purification of gram-negative endotoxin, we found a higher yield of these molecules in the case of tumor-isolated strains. | 1977 | 410196 |
| [investigations on the antimicrobial activity of amin-aldehydecondensates. 1. (communication:) symmetrically substituted animals of formaldehyde (author's transl)]. | in the scope of our research about the antimicrobial activity of aldehyde-amin-condenates a number of partly new aminals was synthesized by reaction of formaldehyde with various secondary amines. structures and physically constants are shown in the tables 1 and 2. the antimicrobial activity is demonstrated by the results of the disk-test (table 3), of the minimal inhibition concentration (mic, talbe 4) and the suspension and area disinfecting test following the method of the dghm (tables 5 and 6 ... | 1977 | 410200 |
| [studies on the activation of humoral defense factors against bacteria in larvae of the wax moth galleria mellonella l]. | the change of lysozyme activity in the hemolymph of the wax moth larvae caused by vaccination is influenced by the size and the dose of the injected particles. the rate of incorporation of those particles into phagocytes has no effect on this process. the change of lysozyme activity correlats negatively with the amount of granulocytes after vaccination. there were no correlations with the amount of other types of the hemocytes, neither with the resistance of the larvae against pseudomonas aerugi ... | 1977 | 410207 |
| [experimental study on keratitis in mice--the influence of topical antibiotics on establishment of pseudomonas aeruginosa (author's transl)]. | | 1977 | 410237 |
| [an acellular vaccine from pseudomonas aeruginosa. ii. -- estimate of immuneserum protective effect by measure of bacterial clearance (author's transl)]. | the protective antibodies obtained in mice with an acellular vaccine p2 from pseudomonas aeruginosa have been titered in vivo by a bacterial clearance technique. the kinetics of the bacterial disappearance from the circulating blood were compared in mice which had been vaccinated or had received injection of specific serum, and in normal mice. the following results were obtained; (a) the disappearance of the bacteria from the blood is quicker in immunized animals; (b) the rate of bacteria in the ... | 1977 | 410340 |
| activity of netilmicin compared with those of gentamicin and tobramycin against enterobacteria and pseudomonas aeruginosa. | the inhibitory activity of netilmicin against 500 isolates of gram-negative bacteria was compared with those of gentamicin and tobramycin. netilmicin was considerably less active than tobramycin and slightly less inhibitory than gentamicin for pseudomonas aeruginosa but was at least as active against escherichia coli and klebsiella pneumoniae as were the other two antibiotics. a few klebsiella and serratia isolates resistant to gentamicin and tobramycin were inhibited by netilmicin. all three an ... | 1977 | 410361 |
| synergistic activity of trimethoprim and amikacin against gram-negative bacilli. | the in vitro effect of trimethoprim on the inhibitory and bactericidal activity of amikacin against 20 strains each of klebsiella pneumoniae and serratia marcescens, 15 strains of escherichia coli, and 10 strains of pseudomonas aeruginosa was examined by the checkerboard technique in microtiter plates. trimethoprim had a synergistic effect on the inhibitory and bactericidal activity of amikacin against the majority of non-pseudomonas strains tested. the mean +/- standard deviation fractional inh ... | 1977 | 410362 |
| [transgenosis with participation of plasmid rp1; indications of the presence of a "composit plasmid" in an interspecies hybrid of escherichia coli]. | one of the transconjugants (1-7) obtained by the authors earlier in the conjugation of escherichia coli j-62 with pseudomonas aeruginosa 1822, besides the plasmic rp1 has acquired the ability to grow without proline and tryptophan. the detailed analysis has shown that in the conjugation of the transconjugant 1-7 with different strains of e. coli the plasmic rp1 and chromosomal genes were transmitted together, but in transduction--by means of bacteriophage p1, independently of each other. the fer ... | 1977 | 410469 |
| primary pseudomonas aeruginosa meningitis in a 2-year-old boy. | | 1977 | 410492 |
| [azlocillin--a new penicillin against pseudomonas aeruginosa and other gram-negative bacteria]. | | 1977 | 410735 |
| mercury and organomercurial resistances determined by plasmids in pseudomonas. | mercury and organomercurial resistance determined by genes on ten pseudomonas aeruginosa plasmids and one pseudomonas putida plasmid have been studied with regard to the range of substrates and the range of inducers. the plasmidless strains were sensitive to growth inhibition by hg(2+) and did not volatilize hg(0) from hg(2+). a strain with plasmid rp1 (which does not confer resistance to hg(2+)) similarly did not volatilize mercury. all 10 plasmids determine mercury resistance by way of an indu ... | 1977 | 410779 |
| pseudomonas aeruginosa mutants resistant to urea inhibition of growth on acetanilide. | pseudomonas aeruginosa ai 3 was able to grow in medium containing acetanilide (n-phenylacetamide) as a carbon source when nh4+ was the nitrogen source but not when urea was the nitrogen source. aiu mutants isolated from strain ai 3 grew on either medium. urease levels in bacteria grown in the presence of urea were 10-fold lower when nh4+ or acetanilide was also in the medium, but there were no apparent differences in urease or its synthesis between strain ai 3 and mutant aiu 1n. the first metabo ... | 1977 | 410788 |
| mechanism of action of tetracaine hydrochloride against pseudomonas aeruginosa. | the mode of action of tetracaine hydrochloride in vitro on pseudomonas aeruginosa was investigates. the inhibitory and bactericidal action of tetracaine hydrochloride in vitro was adversely affected by magnesium ions. observation of cellular lysis, leakage of intracellular materials, dehydrogenase activity, and a higher sensitivity of spheroplasts than of whole cells to tetracaine led to the conclusion that tetracaine acts by damaging the cell membrane. the lytic action of lysozyme was potentiat ... | 1977 | 410897 |
| epidemiological information from active and passive pyocine typing of pseudomonas aeruginosa. | an investigation was carried out to determine the value of active and passive pyocine typing in the study of pseudomonas aeruginosa infections acquired in hospital. active typing was a more reliable and reproducible method than passive typing. both methods were used in studies of nine outbreaks of infection. in six of these episodes there was good agreement between the two methods. less clear-cut results were achieved in the remaining three episodes. in one of these, active typing gave more valu ... | 1977 | 410935 |
| immunogenic properties of serotype strains belonging to homma's serotype schema of pseudomonas aeruginosa. | | 1977 | 410973 |
| [selective effect of propolis in the isolation of listeria monocytogenes (author's transl)]. | propolis is a substance produced by honeybees. it is inhibitory to some bacteria species, mainly gram-positive bacteria, but less inhibitory to listeria monocytogenes (l.m) than to the other gram-positive bacteria tested. in order to obtain selective growth of l.m. from contaminated samples, the effect of propolis in plating media and broths on various strains of bacteria was examined. table i shows the effect of increasing concentrations of propolis in tryptose-agar (ta). l.m. tolerated higher ... | 1977 | 411111 |
| [sensitivity of pseudomonas aeruginosa to ticarcillin and carbenicillin (comparative study)]. | | 1977 | 411159 |
| [comparative study of different schemes of serotyping pseudomonas aeruginosa]. | | 1977 | 411282 |
| pseudomonas aeruginosa infection in cystic fibrosis. diagnostic and prognostic significance of pseudomonas aeruginosa precipitins determined by means of crossed immunoelectrophoresis. a survey. | | 1977 | 411327 |
| factors involved in beta-lactam antibiotic resistance in pseudomonas aeruginosa. | a temperature-sensitive mutant, strain ss, which is assumed to be devoid of beta-lactamase activity and deficient in a permeability barrier to antibiotics, was isolated from a beta-lactamase-less mutant, strain l-2, derived from pseudomonas aeruginosa ifo 3080. by comparing the beta-lactam antibiotic susceptibility between strains ifo 3080, l-2, and ss, the involvement of both beta-lactamase and a permeability barrier in determining the beta-lactam antibiotic resistance was estimated. | 1977 | 411418 |
| physiological control of alkylsulfatase synthesis in pseudomonas aeruginosa: effects of glucose, glucose analogs, and sulfur. | pseudomonas aeruginosa (isolated from soil) synthesizes an alkylsufatase allowing this bacterium to utilize sodium hexan-1-yl sulfate as a source of carbon and sulfur for growth. the formation of the enzyme was induced by this and by other (c4-c16) primary alkylsulfate esters as well as by some (c-8 and c-9) primary alkylsulfonates. secondary (2-yl) alkylsulfate esters did not act as inducers. the induction of alkylsulfatase was markedly inhibited by l-cysteine, l-methionine, sodium sulfide, and ... | 1977 | 411561 |
| cell-wall studies of pseudomonas aeruginosa and its carbenicillin-induced l-form [proceedings]. | | 1977 | 411700 |
| aeruginocine typing of pseudomonas aeruginosa. | | 1977 | 411744 |
| glycolipoprotein from pseudomonas aeruginosa as a protective antigen against p. aeruginosa infection in mice. | after primary subcutaneous immunization of rabbits with glycolipoprotein from pseudomonas aeruginosa bi, indirect hemagglutinating and bacterial agglutinating activities appeared in the antiserum 6 days after immunization and reached a peak between 15 and 20 days. both these in vitro activities paralleled in vivo antipseudomonas-induced leukopenia and mouse passive-protection activities. further experiments indicated that a functional association exists between the hemagglutinating and passive-p ... | 1977 | 411754 |
| synthesis and biological activity of some broad-spectrum n-acylphenyglycine cephalosporins. | the synthesis and the in vitro and in vivo antibacterial activities of a series of n-acylated phenylglycine cephalosporins are described. these compounds exhibit activity against a broad spectrum of gram-positive and gram-negative bacteria including some strains of pseudomonas aeruginosa, a bacterial species normally insensitive to the cephalosporin antibiotics. the cephalosporins were prepared by acylation of cephaloglycin or its 3-tetrazolylthiomethyl analogue. in several cases, the acylations ... | 1977 | 411932 |
| serotyping of pseudomonas aeruginosa from patients with cystic fibrosis of the pancreas. | serotyping of 30 mucoid strains isolated from cystic fibrosis patients was carried out by slide agglutination tests with both live and heat-killed cells and by tube agglutination test with heat-killed cells. comparison of the results obtained by these 2 methods revealed that tube agglutination with heat-killed cells was the superior method. more than half the strains were found to be homma's serotype 15 (group m in the new schema [2]). slide agglutination with live cells did not give clear resul ... | 1977 | 411970 |
| skin necrotizing property of pseudomonas aeruginosa exotoxin. | | 1977 | 411972 |
| [bacteriocinogeny in pseudomonas aeruginosa]. | | 1977 | 412020 |
| [carbenicillin and gentamycin sensitivity of pseudomonas aeruginosa strains isolated in wrocław in the years 1973-1976]. | | 1977 | 412021 |
| [effect of selected disinfectants on pseudomonas aeruginosa]. | | 1977 | 412022 |
| [hospital infections with pseudomonas aeruginosa: i. technical devices and wet areas as sources of infection in intensive care units (author's transl)]. | in an intensive care unit system comprising three surgical intensive care wards bacteriologic investigations on the presence of pseudomonas aeruginosa were carried out over a period of 7 months (as an example for the aetiology of hospital infections). centers of contaminations were found to exist in wet areas and in technical devices (ultrasonic nebulizers, respirators etc.). in many cases, the bacterial strains isolated from patients were found by means of phage-typing to be identical with stra ... | 1977 | 412040 |