Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| holothurians antifungal and antibacterial activity to human pathogens in the persian gulf. | pharmaceutical industries now accept that oceans contain a vast array of organisms with unique biological properties. as investigation of antimicrobial activity, three species of holothuria sea cucumbers (holothuria scabra, holothuria parva and holothuria leucospilota) from the persian gulf, iran, were obtained, their different organs: gonads (g), body wall (bw), intestine tract (it), respiratory tree (rt) were isolated and extracted with organic solvents: ethyl acetate and methanol. antifungal ... | 2017 | 27641487 |
| investigation the efficiency of various methods of volatile oil extraction from trichodesma africanum and their impact on the antioxidant and antimicrobial activities. | currently, there is an increasing interest in developing more efficient techniques for the extraction of phytochemicals. microwaves and ultrasonic extraction methods are promising techniques that can be used for this purpose. | 2017 | 27366351 |
| antimicrobial and cytotoxicity properties of the organic solvent fractions of clerodendrum myricoides (hochst.) r. br. ex vatke: kenyan traditional medicinal plant. | clerodendrum myricoides is a kenyan herbal plant used in the management of respiratory diseases. in the current study, we investigated in vitro antimicrobial activity, cytotoxicity, and phytochemical screening of c. myricoides. | 2017 | 27366347 |
| the effect of spraying different disinfectants on condensational silicone impressions; an in vitro study. | dentistry equipment are exposed to different types of pathogenic microorganisms. the aim of this study was to investigate the effect of spraying three different types of disinfectants on condensational silicones after 5 and 10 min. | 2017 | 26929523 |
| povidone-iodine ointment demonstrates in vitro efficacy against biofilm formation. | anti-infectives used to treat chronic exuding wounds are diluted by wound exudates, absorbed into dressings, metabolised by proteases and destroyed by ph. in order to mimic such effects of exudates, the efficacy of six topical wound agents was assessed undiluted and at 10% concentrations, including povidone-iodine ointment and a silver-impregnated wound dressing, to remove biofilms of pseudomonas aeruginosa, multi-species biofilms of candida albicans and methicillin-resistant staphylococcus aure ... | 2017 | 26968574 |
| antimicrobial activity of aspilia latissima (asteraceae). | we evaluated the antimicrobial activity of aspilia latissima - an abundant plant from the brazilian pantanal region - against candida albicans, candida parapsilosis, candida krusei, candida tropicalis, pseudomonas aeruginosa, enterococcus faecalis, escherichia coli and staphylococcus aureus. the crude extracts and fractions showed activity in all tested microorganisms. the chloroform fraction of the leaves and roots showed the most antimicrobial activity against s. aureus, with an mic of 500 μg/ ... | 2017 | 26691468 |
| antimicrobial activity of aqueous and organic extracts of a saudi medicinal plant: rumex nervosus. | the antimicrobial effect of aerial part of rumex nervosus obtained from the southern region of saudi arabia was evaluated on bacterial strains staphylococcus aureus, methicillin resistant s. aureus, enterococcus faecalis, escherichia coli, pseudomonas aeruginosa, and fungal strain candida albicans. | 2017 | 26681888 |
| biological activities of croton palanostigma klotzsch. | different species of croton are used in traditional amazonian medicine. among the popular uses are treatment of bacterial diseases, poorly healing wounds and fevers. | 2017 | 26246738 |
| development of a novel resin with antimicrobial properties for dental application. | the adhesion of biofilm on dental prostheses is a prerequisite for the occurrence of oral diseases. | 2017 | 25466477 |
| new adamantyl chalcones: synthesis, antimicrobial and anticancer activities. | a new variety of adamantyl chalcones (2, 3a-o) were efficiently prepared by claisen-schmidt reaction of 4-adamantyl acetophenone 2 with a serie of aromatic aldehydes in good yields. their structures were confirmed by spectroscopic data, and the relative configuration of 3d was confirmed by x-ray crystallography. all synthesized chalcones were tested against a panel of grampositive and gram-negative bacteria and pathogenic fungus and displayed strong antibacterial activity against enterococcus fa ... | 2017 | 27558673 |
| pentoxifylline treatment of very low birth weight neonates with nosocomial sepsis. | objective the objective of this study was to assess the result of intravenous pentoxifylline as an adjunct to antibiotic therapy on mortality and morbidity in very low birth weight (vlbw) preterm neonates with nosocomial sepsis. methods for the 18 vlbw preterm neonates, as an adjunct therapy to antibiotics regimens, pentoxifylline (5 mg/kg/h for 6 hours) was administered to premature infants with sepsis on 3 successive days. clinical and laboratory parameters were recorded before and after treat ... | 2017 | 28196391 |
| [antimicrobial resistance trends in pathogens isolated from nosocomial infections]. | the treatment of nosocomial infections is hindered by the increasing antimicrobial resistance pattern of germs that cause them. the objective was to assess trends in resistance of bacteria isolated from nosocomial infections. | 2017 | 26820196 |
| quorum quenching properties of actinobacteria isolated from malaysian tropical soils. | in this study, a total of 147 soil actinobacterial strains were screened for their ability to inhibit response of chromobacterium violaceum cv026 to short chain n-acyl homoserine lactone (ahl) which is a quorum sensing molecule. of these, three actinobacterial strains showed positive for violacein inhibition. we further tested these strains for the inhibition of pseudomonas aeruginosa pao1 quorum sensing-regulated phenotypes, namely, swarming and pyocyanin production. the three strains were foun ... | 2017 | 28364274 |
| star anise (illicium verum hook. f.) as quorum sensing and biofilm formation inhibitor on foodborne bacteria: study in milk. | bacteria use quorum sensing (qs) systems to communicate with each other and regulate microbial group behavior, such as the secretion of virulence factors, including biofilm formation. in order to explore safe, edible agents, the potential of star anise (sa) as an anti-qs and antibiofilm agent and its possible application in milk safety were investigated. staphylococcus aureus , salmonella typhimurium, pseudomonas aeruginosa , and biosensor strain chromobacterium violaceum were selected as test s ... | 2017 | 28294685 |
| evaluation of phytochemicals from medicinal plants of myrtaceae family on virulence factor production by pseudomonas aeruginosa. | virulence factors regulated by quorum sensing (qs) play a critical role in the pathogenesis of an opportunistic human pathogen, pseudomonas aeruginosa in causing infections to the host. hence, in the present work, the anti-virulence potential of the medicinal plant extracts and their derived phytochemicals from myrtaceae family was evaluated against p. aeruginosa. in the preliminary screening of the tested medicinal plant extracts, syzygium jambos and syzygium antisepticum demonstrated a maximum ... | 2017 | 28294414 |
| anti-quorum sensing and anti-biofilm activity of amomum tsaoko (amommum tsao-ko crevost et lemarie) on foodborne pathogens. | cell-to-cell communication or quorum sensing (qs) leads to biofilm formation and causing other virulence factors which are extreme problems for food safety, biofilm related infectious diseases etc. this study evaluated the anti-qs activity of the amomum tsaoko extract (0.5-4 mg/ml) by using chromobacterium violaceum a biosensor strain and biofilm formation by crystal violate assay. experimental results demonstrated that the overall yield of amomum tsao-ko extract was 11.33 ± 0.3% (w/w). mic for ... | 2017 | 28149169 |
| bioavailability-enhanced resveramax™ modulates quorum sensing and inhibits biofilm formation in pseudomonas aeruginosa pao1. | quorum sensing (qs), a cell-to-cell communication mechanism present in many bacterial species plays a key role in regulating the virulence factor and biofilm formation in many pathogens, which causes severe public health risk. therefore, interfering with qs mechanism offers an attractive strategy to combat bacterial infections. in the present study, anti-qs activity of a novel resveratrol formulation, resveramax™, was detected using chromobacterium violaceum biosensor bioassay and the effect of ... | 2017 | 28065820 |
| a medicinal herb cassia alata attenuates quorum sensing in chromobacterium violaceum and pseudomonas aeruginosa. | quorum sensing (qs) has been shown to play a crucial role in the pathogenesis in many bacteria, and attenuation of qs is one of the targets of antimicrobial therapy with particular interest in combating drug resistance. this study reports the qs inhibitory activity of metabolites from cassia alata l. (ca. alata), an important medicinal herb widely used in the treatment of microbial infections. for investigating the qs inhibition (qsi), the potential of ca. alata l., initially, metabolites of the ... | 2017 | 28035685 |
| the effect of sub-inhibitory concentrations of rifaximin on urease production and on other virulence factors expressed by klebsiella pneumoniae, proteus mirabilis, pseudomonas aeruginosa and staphylococcus aureus. | rifaximin, a topical derivative of rifampin, inhibited urease production and other virulence factors at sub-mic concentrations in strains involved in hepatic encephalopathy and the expression of methicillin resistance in staphylococcus aureus. in particular, urease production was affected in all proteus mirabilis and klebsiella pneumoniae strains as well as in all tested pseudomonas aeruginosa isolates. other exotoxins, synthesized by p. aeruginosa, such as protease, gelatinase, lipase, lecithin ... | 2017 | 27285830 |
| diarylheptanoids from alnus viridis ssp. viridis and alnus glutinosa: modulation of quorum sensing activity in pseudomonas aeruginosa. | diarylheptanoids from the barks of alnus viridis ssp. viridis (green alder) and alnus glutinosa (black alder) were explored for anti-quorum sensing activity. chemicals with anti-quorum sensing activity have recently been examined for antimicrobial applications. the anti-quorum sensing activity of the selected diarylheptanoids was determined using two biosensors, namely pseudomonas aeruginosa pao1 and chromobacterium violaceum cv026. although all of the investigated compounds negatively influence ... | 2017 | 27220074 |
| neonatal bacterial conjunctivitis in korea in the 21st century. | to investigate the microbial cause and antibiotic susceptibility of neonatal bacterial conjunctivitis in korean patients in the 21st century. | 2017 | 28002109 |
| under-utilization of taps in intensive care unit as a cause of reservoirs of nonfermenting gram-negative bacilli. | the under-utilisation of taps is associated with the generation of reservoirs of non-fermenting gram-negative bacilli with the ability to disseminate. we describe the detection and approach of the problem in an icu. | 2017 | 28291668 |
| prevalence of multidrug resistant uropathogenic bacteria in pediatric patients of a tertiary care hospital in eastern india. | today, because systemic infections such as urinary tract infection (uti) affect even pediatric patients, antibiotic resistant bacteria have become a constant clinical challenge. in the present study, a total of 1054 urine samples were collected from pediatric patients over 18 months. from these samples, 510 isolates of pathogenic bacteria were collected using hicrome uti agar. antibiotic sensitivity tests of isolates were performed using the kirby-bauer method. two gram-positive bacteria (entero ... | 2017 | 26617250 |
| the wide spectrum high biocidal potency of bioxy formulation when dissolved in water at different concentrations. | traditional surface disinfectants that have long been applied in medicine, animal husbandry, manufacturing and institutions are inconvenient at best and dangerous at worst. moreover, some of these substances have adverse environmental impacts: for example, quaternary ammonium compounds ("quats") are reproductive toxicants in both fish and mammals. halogens are corrosive both to metals and living tissues, are highly reactive, can be readily neutralized by metals, and react with organic matter to ... | 2017 | 28207828 |
| a decade of development of chromogenic culture media for clinical microbiology in an era of molecular diagnostics. | in the last 25 years, chromogenic culture media have found widespread application in diagnostic clinical microbiology. in the last decade, the range of media available to clinical laboratories has expanded greatly, allowing specific detection of additional pathogens, including pseudomonas aeruginosa, group b streptococci, clostridium difficile, campylobacter spp., and yersinia enterocolitica. new media have also been developed to screen for pathogens with acquired antimicrobial resistance, inclu ... | 2017 | 28122803 |
| in vitro inhibition of clostridium difficile by commercial probiotics: a microcalorimetric study. | the aim of the study was to investigate the influence of some commercial probiotics on the growth of clostridium difficile using isothermal microcalorimetry, a technique which can monitor the real time growth of bacteria. commercial probiotic strains and products, lactobacillus acidophilus la-5(®), bifidobacterium lactis bb-12(®), probio 7(®) and symprove™ were co-cultured with c. difficile in brain heart infusion (bhi) broth supplemented with 0.1% (w/v) l-cysteine hydrochloride and 0.1% (w/v) s ... | 2017 | 27923699 |
| bacterial cellulose-zinc oxide nanocomposites as a novel dressing system for burn wounds. | bacterial cellulose possesses physical and mechanical properties of an ideal wound dressing material but lack of antimicrobial activity limits its biomedical applications. therefore, in current study, the inherent wound healing characteristics of bacterial cellulose and antimicrobial properties of zinc oxide nanoparticles were combined. the reinforcement (impregnation) of zinc oxide nanoparticles into bacterial cellulose sheets was confirmed through various characterization techniques. the antim ... | 2017 | 28325319 |
| risk of infection transmission in curvilinear array echoendoscopes: results of a prospective reprocessing and culture registry. | the complex design of the elevator mechanism in duodenoscopes has been recognized as a challenge for disinfection and recently implicated as a potential source of persistent bacterial contamination. curvilinear array (cla) echoendoscopes also have an elevator mechanism; however, there are no recommendations or data regarding the risk of persistent bacterial contamination of echoendoscopes. here we hoped to determine the yield of microbial growth with routine bacterial surveillance cultures of re ... | 2017 | 27478029 |
| changes in the conjunctival bacterial flora of patients hospitalized in an intensive care unit. | to identify the changes in aerobic conjunctival bacterial flora and to correlate culture results with physical health and the duration of patients' hospitalization in an intensive care unit (icu). | 2017 | 28380097 |
| prenylated flavonoids from the stems and roots of tripterygium wilfordii. | phytochemical investigation on the stems and roots of tripterygium wilfordii led to the isolation and characterization of three new prenylated flavanones, tripteryols a-c (1-3), along with (±)-5,4'-dihydroxy-2'-methoxy-6',6″-dimethypyraro-(2″,3″:7,8)-6-methyflavanone (4), and ((2s)-5,7,4'-trihydroxy-2'-methoxy-8,5'-di(3-methyl-2-butenyl)-6-methylflavanone (5). structures of the compounds 1-5 were elucidated using spectroscopic techniques, such as uv, ir, nmr (1d and 2d), and hresi-ms. tripteryol ... | 2017 | 28389278 |
| isolation and characterization of pah-degrading bacteria from the eastern province, saudi arabia. | contaminated sediment samples were collected from the eastern province, saudi arabia for isolation of pyrene- and phenanthrene-degrading bacteria by enrichment method. four isolates were morphologically characterized as gram-negative rod strains and 16s rrna sequence analysis revealed the isolates as closely related to pseudomonas aeruginosa, p. citronellolis, ochrobactrum intermedium and cupriavidus taiwanensis. degradation of the polycyclic aromatic hydrocarbons (pahs) by the latter three stra ... | 2017 | 27912917 |
| [community acquired urinary tract infections in older adults]. | background community acquired urinary tract infections (cauti) in adults are common ailments. older adults are prone to infectious diseases, diagnosis can be difficult, their etiologic and antimicrobial resistance are poorly known. objectives to evaluate the incidence discriminated by sex, symptoms, and to determine pathogens and their antimicrobial resistance rate. methods a retrospective, descriptive and comparative study. we analyze uricultures among 2013 in the hospital nacional de clinicas ... | 2017 | 28379126 |
| prevalence, risk factors, outcomes, and molecular epidemiology of mcr-1-positive enterobacteriaceae in patients and healthy adults from china: an epidemiological and clinical study. | the mcr-1 gene confers transferable colistin resistance. mcr-1-positive enterobacteriaceae (mcrpe) have attracted substantial medical, media, and political attention; however, so far studies have not addressed their clinical impact. herein, we report the prevalence of mcrpe in human infections and carriage, clinical associations of mcr-1-positive escherichia coli (mcrpec) infection, and risk factors for mcrpec carriage. | 2017 | 28139431 |
| in vitro activity of ceftazidime/avibactam against urinary isolates from patients in a phase 3 clinical trial programme for the treatment of complicated urinary tract infections. | to evaluate the in vitro activity of ceftazidime/avibactam relative to comparator agents against gram-negative isolates from a phase 3 clinical trial programme for complicated urinary tract infections (recapture). | 2017 | 28088768 |
| antimicrobial activity of ceftazidime-avibactam and comparator agents when tested against bacterial isolates causing infection in cancer patients (2013-2014). | we evaluated the antimicrobial susceptibility of 623 gram-negative organisms causing infection in patients with cancer in 52 united states hospitals (2013-2014) as part of the international network for optimal resistance monitoring (inform) program. isolates were tested for susceptibility by broth microdilution method. β-lactamase encoding genes were evaluated for all escherichia coli and klebsiella spp. with an extended-spectrum β-lactamase (esbl) phenotype by microarray-based assay. esbl-pheno ... | 2017 | 28069328 |
| searching for a potential antibacterial lead structure against bacterial biofilms among new naphthoquinone compounds. | the aims of this study were to design, synthesize and to evaluate 2-hydroxy-3-phenylsulfanylmethyl-[1,4]-naphthoquinones against gram-negative and gram-positive bacterial strains, including methicillin-resistant staphylococcus aureus (mrsa) and its biofilm, to probe for potential lead structures. | 2017 | 27930849 |
| attributable mortality of hospital-acquired bloodstream infections in ireland. | to estimate the attributable mortality of hospital-acquired bloodstream infections (ha-bsi) in ireland. | 2017 | 28359546 |
| cutaneous burn injury modulates urinary antimicrobial peptide responses and the urinary microbiome. | characterization of urinary bacterial microbiome and antimicrobial peptides after burn injury to identify potential mechanisms leading to urinary tract infections and associated morbidities in burn patients. | 2017 | 28333758 |
| fosfomycin and comparator activity against select enterobacteriaceae, pseudomonas, and enterococcus urinary tract infection isolates from the united states in 2012. | fosfomycin is a broad-spectrum cell wall active agent that inhibits the mura enzyme involved in peptidoglycan synthesis and is fda-approved for treatment of uncomplicated urinary tract infections (utis) caused by escherichia coli and enterococcus faecalis in women. data regarding the susceptibility of recent uti isolates to fosfomycin are limited. | 2017 | 28285420 |
| chemical composition, antioxidant and antibacterial activities of tamarix balansae j. gay aerial parts. | a previously undescribed phenolic sulphate ester, potassium 34-dihydroxy-3-methoxybenzoic acid methyl ester-5-sulphate (1), along with nine known flavonoids, kaempferol-3-o-potassium sulphate-4',7-dimethyl ether (2), kaempferol-4',7-dimethyl ether (3), rhamnocitrin-3-o-potassium sulphate (4), rhamnocitrin (5), kaempferol (6), quercetin (7), afzelin (8), quercetin-3-o-α-l-rhamnopyranoside (9) and luteolin-3'-o-potassium sulphate (10) were isolated from the aerial parts of tamarix balansae. struct ... | 2017 | 28281364 |
| adjuvant antibiotic activity of acidic sophorolipids with potential for facilitating wound healing. | the sophorolipid class of biosurfactants are finding increasing use in personal care as well as pharmaceutical products and have the potential to disrupt biofilm formation and inhibit growth in a variety of clinically relevant organisms. in order to investigate potential biomedical applications of sophorolipids derived from non-pathogenic organisms, we fractionated and purified glycolipid biosurfactant sophorolipids produced by the yeast starmerella bombicola, which yielded both acidic c 18-1 ac ... | 2017 | 28242666 |
| synthesis and antimicrobial evaluation of cationic low molecular weight amphipathic 1,2,3-triazoles. | a library of 28 small cationic 1,4-substituted 1,2,3-triazoles was prepared for studies of antimicrobial activity. the structures addressed the pharmacophore model of small antimicrobial peptides and an amphipathic motif found in marine antimicrobials. eight compounds showed promising antimicrobial activity, of which the most potent compound 10b displayed minimum inhibitory concentrations of 4-8μg/ml against streptococcus agalacticae, staphylococcus aureus, pseudomonas aeruginosa, escherichia co ... | 2017 | 28189422 |
| nipple shields in transaxillary breast augmentation. | infection after breast augmentation occurs in 1.1% to 2.5% of patients. bacterial contamination of the implants could explain some complications of breast implant surgery, including infection, capsular contracture and even anaplastic large cell lymphoma. because of the evidence of bacterial spread from the nipple, nipple shields have been proposed as a routine maneuver to avoid contamination of the implants. | 2017 | 28166134 |
| screening for antibacterial and antibiofilm activities in astragalus angulosus. | in a search for finding novel therapeutic agents, extracts from an endemic lebanese plant, astragalus angulosus, were evaluated for their potential in-vitro antibacterial and antibiofilm activities against three gram-positive bacterial strains; staphylococcus epidermidis (cip444), staphylococcus aureus (atcc25923), and enterococcus faecalis (atcc29212); in addition to two gram-negative strains, escherichia coli (atcc35218) and pseudomonas aeruginosa (atcc27853). | 2017 | 28163960 |
| cold atmospheric pressure plasma elimination of clinically important single- and mixed-species biofilms. | mixed-species biofilms reflect the natural environment of many pathogens in clinical settings and are highly resistant to disinfection methods. an indirect cold atmospheric-pressure air-plasma system was evaluated under two different discharge conditions for its ability to kill representative gram-positive (staphylococcus aureus) and gram-negative (pseudomonas aeruginosa) pathogens. plasma treatment of individual 24-h-old biofilms and mixed-species biofilms that contained additional species (ent ... | 2017 | 28161488 |
| [early results of adjuvant topical treatment of recurrent osteomyelitis with absorbable antibiotic carriers]. | background treatment of musculoskeletal infections principally consists of radical surgical debridement and systemic administration of antibiotics. additional local antibiotic therapy is not yet generally established, and lacks evidence-based proof of efficacy. nonetheless, there are a variety of practical approaches, as most specialised departments are unwilling to forego this option. the established polymethylmetacrylate (pmma) carrier system has a number of practical disadvantages. this has l ... | 2017 | 28081583 |
| ozone therapy as an adjuvant for endondontic protocols: microbiological - ex vivo study and citotoxicity analyses. | this study evaluated the antimicrobial efficacy of ozone therapy in teeth contaminated with pseudomonas aeruginosa, enterococcus faecalis, and staphylococcus aureus using a mono-species biofilm model. parallel to this, the study aimed to evaluate the cytotoxicity of ozone for human gingival fibroblasts. material and methods: one hundred and eighty single-root teeth were contaminated with a mono-species biofilm of enterococcus faecalis, pseudomonas aeruginosa, and staphylococcus aureus. groups we ... | 2017 | 28076466 |
| isolation of rhamnolipids-producing cultures from faeces: influence of interspecies communication on the yield of rhamnolipid congeners. | the aim of this study was to evaluate the ability of bacterial cultures isolated from cattle, poultry or pig faeces and manure to produce rhamnolipids, as well as to investigate the influence of interspecies communication on possible quantitative differences in the production of rhamnolipid congeners. initial screening methods (oil spreading, drop collapse, haemolytic activity and emulsification activity) showed that approximately 36% of the 51 isolated cultures exhibited the ability to produce ... | 2017 | 28043869 |
| ofloxacin loaded gellan/pva nanofibers - synthesis, characterization and evaluation of their gastroretentive/mucoadhesive drug delivery potential. | the purpose of this investigation is to formulate a gastroretentive sustained drug release system for ofloxacin to improve its retention time, pharmacological activity, bioavailability and therapeutic efficacy in the stomach. ofloxacin loaded gellan/poly vinyl alcohol (pva) nanofibers were fabricated using a simple and versatile electrospinning technique. the fabricated nanofibers were evaluated for percent drug encapsulation efficiency and in vitro drug release in simulated gastric medium (ph1. ... | 2017 | 27987752 |
| the pathogenic potential of proteus mirabilis is enhanced by other uropathogens during polymicrobial urinary tract infection. | urinary catheter use is prevalent in health care settings, and polymicrobial colonization by urease-positive organisms, such as proteus mirabilis and providencia stuartii, commonly occurs with long-term catheterization. we previously demonstrated that coinfection with p. mirabilis and p. stuartii increased overall urease activity in vitro and disease severity in a model of urinary tract infection (uti). in this study, we expanded these findings to a murine model of catheter-associated uti (cauti ... | 2017 | 27895127 |
| bacteriological quality of the wastewater used for irrigation at the vegetable farms in korle-bu teaching hospital, accra metropolis, ghana. | many developing countries, including ghana, are water stressed. as such, farmers, particularly those in urban areas, have adopted the use of wastewater for irrigation. this study evaluated the bacteriological water quality of the wastewater used for irrigation in the vegetable farms at korle-bu teaching hospital (kbth), accra metropolis, ghana. in all, 40 wastewater samples were collected and analysed bacteriologically using the total aerobic plate count method. the isolated bacteria were identi ... | 2017 | 26862131 |
| light and temperature effects on bioactivity in diatoms. | isolates of five pelagic north atlantic marine diatoms (bacillariophyceae): attheya longicornis, chaetoceros socialis, chaetoceros furcellatus, skeletonema marinoi and porosira glacialis were cultivated in large photobioreactors at two light and two temperature regimes to test if this affected bioactivity. we screened for bioactivity in assays representing five different therapeutic areas: diabetes ii (ptp1b), cancer (melanoma cells, a2058), anti-oxidants (frap), immunomodulation (tnfa) and anti ... | 2017 | 27057087 |
| in vitro antimicrobial evaluation of toothpastes with natural compounds. | this in vitro study evaluated the antimicrobial effects of commercial toothpastes containing natural compounds. | 2017 | 26929699 |
| drinking water quality and public health in southwestern saudi arabia: the need for a national monitoring program. | the aim was to investigate the bacteriological quality of drinking water, and explore the factors involved in the knowledge of the public about the quality of drinking water in najran region, saudi arabia. | 2017 | 25657607 |
| infectious anastomotic pseudoaneurysm complicating renal allograft: case report and review of literature. | infectious anastomotic pseudoaneurysm complicating renal transplant is rare, but probably under-reported with <30 cases worldwide. we report a 45-year-old man with hypertension, diabetes mellitus and end stage renal failure, who had a renal transplant anastomosed to the right external iliac artery and vein. postoperatively, he made a slow recovery with malaise and persistent vague right iliac fossa discomfort. ultrasound scan 1 month postoperatively showed perinephric collection, and fluid cultu ... | 2017 | 28260939 |
| comparison of the antimicrobial activity of direct pulp-capping materials: mineral trioxide aggregate-angelus and biodentine. | to compare the antimicrobial activity of the tricalcium silicate-based biodentine (bd) and mineral trioxide aggregate (mta)-angelus cement with the aid of agar diffusion test. | 2017 | 27994321 |
| sepsis due to erysipelothrix rhusiopathiae in a patient with chronic lymphocytic leukemia associated with bronchopneumonia due to pseudomonas aeruginosa and escherichia coli: a case report. | the present report describes a case of sepsis due to erysipelothrix rhusiopathiae in a patient with b-cell chronic lymphocytic leukemia with no animal exposure, associated with concomitant bronchopneumonia due to pseudomonas aeruginosa and escherichia coli. | 2017 | 26015797 |
| finding novel antibiotic substances from medicinal plants - antimicrobial properties of nigella sativa directed against multidrug-resistant bacteria. | the progressive rise in multidrug-resistant (mdr) bacterial strains poses serious problems in the treatment of infectious diseases. while the number of newly developed antimicrobial compounds has greatly fallen, the resistance of pathogens against commonly prescribed drugs is further increasing. this rise in resistance illustrates the need for developing novel therapeutic and preventive antimicrobial options. the medicinal herb nigella sativa and its derivatives constitute promising candidates. ... | 2017 | 28386474 |
| gallium-modified chitosan/poly(acrylic acid) bilayer coatings for improved titanium implant performances. | a gallium-modified chitosan/poly(acrylic acid) bilayer was obtained by electrochemical techniques on titanium to reduce orthopaedic and/or dental implants failure. the bilayer in vitro antibacterial properties and biocompatibility were evaluated against escherichia coli and pseudomonas aeruginosa and on mg63 osteoblast-like cells, respectively. gallium loading into the bilayer was carefully tuned by the electrochemical deposition time to ensure the best balance between antibacterial activity and ... | 2017 | 28385242 |
| polymyxin b-induced diffuse cutaneous hyperpigmentation. | polymyxin b is a polypeptide-antibiotic, primarily used for resistant gram-negative infections, first obtained from bacterium bacillus polymyxa in the late 1940s. antibiotic spectrum are restricted to mainly gram negative bacterias like enterobacter, e. coli, klebsiella, salmonella, pasteurella, bordetella, shigella; and particularly organisms like pseudomonas aeruginosa and acinetobacter baumannii, which are extremely potent to acquire antibiotic resistance. side effects include neurotoxicity a ... | 2017 | 28384882 |
| synthesis and evaluation of adenosine containing 3-arylfuran-2(5h)-ones as tyrosyl-trna synthetase inhibitors. | tyrosyl-trna synthetase (tyrrs) is an aminoacyl-trna synthetase family protein that possesses an essential role in bacterial protein synthesis. the synthesis, structure-activity relationship, and evolution of a novel series of adenosine-containing 3-arylfuran-2(5h)-ones as tyrrs inhibitors are described. advanced compound d3 from this series exhibited excellent affinity for tyrrs with ic50 of 0.61 ± 0.04 μm. bacterial growth inhibition assays demonstrated that d3 showed submicromolar antibacteri ... | 2017 | 28380394 |
| biological synthesis of gold and silver chloride nanoparticles by glycyrrhiza uralensis and in vitro applications. | the current study highlights the rapid biosynthesis of gold nanoparticles (gu-aunps) and silver chloride nanoparticles (gu-agclnps) by aqueous root extract of glycyrrhiza uralensis, a medicinal plant. g. uralensis has been reported for anticancer and hepatoprotective effects. the reduction of chloroauric acid and silver nitrate by the glycyrrhiza root extract prompted the formation of gu-aunps and gu-agclnps within 4 and 40 min at 80 °c, respectively. the complete reaction did not require supple ... | 2017 | 28375686 |
| seasonal variation of brazilian red propolis: antibacterial activity, synergistic effect and phytochemical screening. | the aim of this study was to investigate the effect of the dry and rainy season on the antibacterial activity and chemical composition of the brazilian red propolis. the samples were collected in rainy (rp-per) and dry (rp-ped) seasons and analyzed by hplc-dad. the extracts were tested alone and in association with antibiotics against escherichia coli, pseudomonas aeruginosa and staphylococcus aureus. the hplc analysis identified luteolin and quercetin as the main compounds. seasonal variation w ... | 2017 | 28359875 |
| identification and characterization of a chemical compound that inhibits methionyl-trna synthetase from pseudomonas aeruginosa. | pseudomonas aeruginosa is an opportunistic pathogen problematic in causing nosocomial infections and is highly susceptible to development of resistance to multiple antibiotics. the gene encoding methionyl-trna synthetase (metrs) from p. aeruginosa was cloned and the resulting protein characterized. metrs was kinetically evaluated and the km for its three substrates, methionine, atp and trnamet were determined to be 35, 515, and 29 μm, respectively. p. aeruginosa metrs was used to screen two chem ... | 2017 | 28359232 |
| bioactivity of variant molecular weight chitosan against drug-resistant bacteria isolated from human wounds. | chitosan available from crab shells is usually of high molecular weight which may result in reduced efficiency for its antibacterial activity. one of the techniques for improving chitosan antibacterial efficiency is reducing its molecular weight. the irradiation of chitosan by gamma radiations is considered to be one of the most effective and widely used methods for improving its antibacterial activity. chitosan obtained from crab shells was irradiated with gamma radiations at different doses, a ... | 2017 | 28358617 |
| rainwater harvesting in american samoa: current practices and indicative health risks. | roof-harvested rainwater (rhrw) is an important alternative source of water that many island communities can use for drinking and other domestic purposes when groundwater and/or surface water sources are contaminated, limited, or simply not available. the aim of this pilot-scale study was to investigate current rhrw practices in american samoa (as) and to evaluate and compare the quality of water from common potable water sources including rhrw stored in tanks, untreated stream water, untreated ... | 2017 | 28357803 |
| core-genome scaffold comparison reveals the prevalence that inversion events are associated with pairs of inverted repeats. | genome rearrangement describes gross changes of chromosomal regions, plays an important role in evolutionary biology and has profound impacts on phenotype in organisms ranging from microbes to humans. with more and more complete genomes accomplished, lots of genomic comparisons have been conducted in order to find genome rearrangements and the mechanisms which underlie the rearrangement events. in our opinion, genomic comparison of different individuals/strains within the same species (pan-genom ... | 2017 | 28356070 |
| antibiotic resistance patterns of bacteria isolated from indwelling foley catheters following tube cystostomy in goats with obstructive urolithiasis. | tube cystostomy is a surgical method used for managing obstructive urolithiasis and involves placement of a foley catheter into the urinary bladder. we identified and evaluated the antibiotic resistance patterns of bacteria isolated from indwelling foley catheters following tube cystostomy in goats with obstructive urolithiasis. urine samples collected over a 10-y period from catheter tips at the time of removal were submitted for bacteriologic culture and antibiotic susceptibility testing. resi ... | 2017 | 28351339 |
| involvement of oxidative stress in protocatechuic acid-mediated bacterial lethality. | the involvement of oxidative stress in protocatechuic acid-mediated bacterial lethality was investigated. minimum inhibitory concentrations (mic) and minimum bactericidal concentration (mbc) of protocatechuic acid against escherichia coli, pseudomonas aeruginosa, and staphylococcus aureus are 600 and 700 μg/ml, 600 and 800 μg/ml, and 600 and 800 μg/ml, respectively. the optical densities and colony-forming units of protocatechuic acid-treated bacteria decreased in time-dependent manner. protocat ... | 2017 | 28349673 |
| fragment library screening identifies hits that bind to the non-catalytic surface of pseudomonas aeruginosa dsba1. | at a time when the antibiotic drug discovery pipeline has stalled, antibiotic resistance is accelerating with catastrophic implications for our ability to treat bacterial infections. globally we face the prospect of a future when common infections can once again kill. anti-virulence approaches that target the capacity of the bacterium to cause disease rather than the growth or survival of the bacterium itself offer a tantalizing prospect of novel antimicrobials. they may also reduce the propensi ... | 2017 | 28346540 |
| potential antibacterial activity of some saudi arabia honey. | the aim of this study was to investigate the potential antibacterial activity of some saudi arabia honey against selected bacterial strains of medical importance. | 2017 | 28344408 |
| attribution of antibacterial and antioxidant activity of cassia tora extract toward its growth promoting effect in broiler birds. | the study was conducted to evaluate the attribution of antibacterial and antioxidant activity of methanolic extract of cassia tora toward its growth promoting effect in broiler birds. | 2017 | 28344406 |
| exogenous l-valine promotes phagocytosis to kill multidrug-resistant bacterial pathogens. | the emergence of multidrug-resistant bacteria presents a severe threat to public health and causes extensive losses in livestock husbandry and aquaculture. effective strategies to control such infections are in high demand. enhancing host immunity is an ideal strategy with fewer side effects than antibiotics. to explore metabolite candidates, we applied a metabolomics approach to investigate the metabolic profiles of mice after klebsiella pneumoniae infection. compared with the mice that died fr ... | 2017 | 28321214 |
| detection of brucellosis in sika deer ( cervus nippon ) through loop-mediated isothermal amplification (lamp). | brucellosis (brucella bovis) in sika deer ( cervus nippon ) can cause enormous losses to stag breeding, especially in areas in which stag breeding has become an important industry. it also poses a threat to humans because it is a zoonotic disease. use of the loop-mediated isothermal amplification (lamp) assay has been poorly described in the diagnosis of brucellosis in deer. we developed a lamp assay targeting the omp25 gene sequence to detect brucellosis (brucella bovis) in sika deer. the react ... | 2017 | 28318383 |
| synthesis, antimicrobial activity and toxicity to nematodes of cyclam derivatives. | the antimicrobial activity and toxicity to nematodes of the cyclam salt [h2{h2((4-cf3)phch2)2cyclam}](ch3coo)2⋅(ch3cooh)2 were evaluated. estimated minimum inhibitory concentrations (mics) of 9, 261 and 15 µg/ml were obtained for escherichia coli, pseudomonas aeruginosa and staphylococcus aureus, respectively. for selected candida spp., the estimated mics obtained ranged from 32 µg/ml to 63 µg/ml. bactericidal activity was demonstrated but the compound was not reliably fungicidal. concentrations ... | 2017 | 28315730 |
| molecular detection of six virulence genes in pseudomonas aeruginosa isolates detected in children with urinary tract infection. | although a vast majority of urinary tract infections (utis) are caused by e. coli, epidemiological reports have indicated an increasing rate of such infections caused by some other opportunistic organisms including pseudomonas aeruginosa. antimicrobial susceptibility and pathogenesis mechanisms of p. aeruginosa are poorly understood. the aim of this study was to detect some virulence factor genes and antimicrobial susceptibility patterns of p. aeruginosa isolates detected in patients with uti, i ... | 2017 | 28315724 |
| bactericidal effect of pterostilbene alone and in combination with gentamicin against human pathogenic bacteria. | the antibacterial activity of pterostilbene in combination with gentamicin against six strains of gram-positive and gram-negative bacteria were investigated. the minimum inhibitory concentration and minimum bactericidal concentration of pterostilbene were determined using microdilution technique whereas the synergistic antibacterial activities of pterostilbene in combination with gentamicin were assessed using checkerboard assay and time-kill kinetic study. results of the present study showed th ... | 2017 | 28304328 |
| emerging trends in antibiotic resistance: implications for emergency medicine. | many bacteria are demonstrating increasing levels of resistance to commonly used antibiotics. while this has implications for the healthcare system as a whole, many patients infected with these resistant organisms will initially present to the emergency department (ed). the purpose of this review is to provide a summary of current trends in infections caused by the most clinically relevant resistant organisms encountered in emergency medicine. | 2017 | 28302376 |
| chlorine dioxide oxidation of escherichia coli in water - a study of the disinfection kinetics and mechanism. | this study investigated the kinetics and mechanism of chlorine dioxide (clo2) inactivation of a gram-negative bacteria escherichia coli (atcc 35218) in oxidant demand free (odf) water in detail as a function of disinfectant concentration (0.5-5.0 mg/l), water ph (6.5-8.5), temperature variations (4-37°c) and bacterial density (10(5)-10(7) cfu/ml). the effects of clo2 on bacterial cell morphology, outer membrane permeability, cytoplasmic membrane disruption and intracellular enzymatic activity we ... | 2017 | 28301286 |
| the effect of urinary catheters on microbial biofilms and catheter associated urinary tract infections. | the aims of this study were to determine relationship between biofilm producer microorganisms attached to urinary catheters (ucs) and urinary catheter-associated urinary tract infections (cautis), to determine the rate of cauti development and the relationship between cauti and catheterization period in catheterized patients. | 2017 | 28299769 |
| antimicrobial peptides at work: interaction of myxinidin and its mutant wmr with lipid bilayers mimicking the p. aeruginosa and e. coli membranes. | antimicrobial peptides are promising candidates as future therapeutics in order to face the problem of antibiotic resistance caused by pathogenic bacteria. myxinidin is a peptide derived from the hagfish mucus displaying activity against a broad range of bacteria. we have focused our studies on the physico-chemical characterization of the interaction of myxinidin and its mutant wmr, which contains a tryptophan residue at the n-terminus and four additional positive charges, with two model biologi ... | 2017 | 28294185 |
| microbiological diagnosis and antimicrobial sensitivity profiles in diseased free-living raptors. | free-living raptors (birds of prey) can act as reservoirs of potentially zoonotic agents but they also can be affected by microorganisms as target hosts. in this retrospective study, microbiological results (n=663) and antibiotic sensitivity profiles (n=108) of bacterial isolates were analyzed from diseased free-living raptors. sixty-nine percent of cases (n=457) yielded bacteria: 58% were in pure culture and 42% were of different species. remarkably, samples from necropsies (47%) had higher per ... | 2017 | 28290221 |
| bacteriophage sp6 encodes a second tailspike protein that recognizes salmonella enterica serogroups c2 and c3. | sp6 is a salmonella phage closely related to coliphage k1-5. k1-5 is notable in that it encodes two polysaccharide-degrading tailspike proteins, an endosialidase that allows it to infect e. coli k1, and a lyase that enables it to infect k5 strains. sp6 is similar to k1-5 except that it encodes a p22-like endorhamnosidase tailspike, gp46, allowing it to infect group b salmonella. we show here that sp6 can also infect salmonella serogroups c2 and c3 and that a mutation in a putative second tailspi ... | 2017 | 28285722 |
| vitamin c pretreatment enhances the antibacterial effect of cold atmospheric plasma. | bacterial biofilms are three-dimensional structures containing bacterial cells enveloped in a protective polymeric matrix, which renders them highly resistant to antibiotics and the human immune system. therefore, the capacity to make biofilms is considered as a major virulence factor for pathogenic bacteria. cold atmospheric plasma (cap) is known to be quite efficient in eradicating planktonic bacteria, but its effectiveness against biofilms has not been thoroughly investigated. the goal of thi ... | 2017 | 28275584 |
| plakofuranolactone as a quorum quenching agent from the indonesian sponge plakortis cf. lita. | there is an urgent need for novel strategies to fight drug resistance and multi-drug resistance. as an alternative to the classic antibiotic therapy, attenuation of the bacteria virulence affecting their quorum sensing (qs) system is a promising approach. quorum sensing (qs) is a genetic regulation system that allows bacteria to communicate with each other and coordinate group behaviors. a new γ-lactone that is capable of inhibiting the lasi/r qs system, plakofuranolactone (1), was discovered in ... | 2017 | 28264490 |
| cyclic-di-gmp regulates lipopolysaccharide modification and contributes to pseudomonas aeruginosa immune evasion. | pseudomonas aeruginosa is a gram-negative bacterial pathogen associated with acute and chronic infections. the universal cyclic-di-gmp second messenger is instrumental in the switch from a motile lifestyle to resilient biofilm as in the cystic fibrosis lung. the sadc diguanylate cyclase is associated with this patho-adaptive transition. here, we identify an unrecognized sadc partner, wara, which we show is a methyltransferase in complex with a putative kinase, warb. we established that wara bind ... | 2017 | 28263305 |
| evaluation of the antibacterial effects of flavonoid combination from the leaves of dracontomelon dao by microcalorimetry and the quadratic rotary combination design. | skin infectious disease is a common public health problem due to the emergence of drug-resistant bacteria caused by the antibiotic misuse. dracontomelon dao (blanco) merr. et rolfe, a traditional chinese medicine, has been used for the treatment of various skin infectious diseases over 1000 of years. previous reports have demonstrated that the leaves of d. dao present favorable antibacterial activity against escherichia coli, pseudomonas aeruginosa, staphylococcus aureus, and bacillus subtitles. ... | 2017 | 28261101 |
| synthesis and characterization of core-shell bimetallic nanoparticles for synergistic antimicrobial effect studies in combination with doxycycline on burn specific pathogens. | nano-medicine is a breakthrough discovery in the healthcare sector. doxycycline is a new generation antibiotic which is proved to be a boon in the treatment of patients with complicated skin infections. we have tried to explore the benefits of synthesized bimetallic silver-gold nanoparticles in combination with new generation antibiotic for burn infections. the bimetallic nanoparticles synthesized by core-shell method were characterized using scanning electron microscopy equipped with an energy ... | 2017 | 28254569 |
| in vitro antibacterial activity and in vivo therapeutic effect of sesbania grandiflora in bacterial infected silkworms. | antibiotic resistance is a serious problem worldwide. searching for new potential agents is, therefore, essential. the bark of sesbania grandiflora (l.) pers. (fabaceae) has been used in folk medicine against various diseases. | 2017 | 28253823 |
| incidence, bacteriology, and clinical outcome of ventilator-associated pneumonia at tertiary care hospital. | ventilator-associated pneumonia (vap) is the most frequent intensive care unit acquired infection. | 2017 | 28250674 |
| dataset of proteomics analysis of aging c. elegans exposed to pseudomonas aeruginosa strain pa01. | here, we present the proteomics dataset of young and middle-aged caenorhabditis elegans (c. elegans) exposed to pseudomonas aeruginosa (p. aeruginosa strain pa01), which is related to the article "proteomic identification of virulence-related factors in young and aging c. elegans infected with pseudomonas aeruginosa" (c. d. king et. al, in-revisions). this dataset was generated to better understand the effects of aging on molecular mechanisms involved in host response to pathogen exposure. prote ... | 2017 | 28243620 |
| oligomeric lipoprotein pelc guides pel polysaccharide export across the outer membrane of pseudomonas aeruginosa. | secreted polysaccharides are important functional and structural components of bacterial biofilms. the opportunistic pathogen pseudomonas aeruginosa produces the cationic exopolysaccharide pel, which protects bacteria from aminoglycoside antibiotics and contributes to biofilm architecture through ionic interactions with extracellular dna. a bioinformatics analysis of genome databases suggests that gene clusters for pel biosynthesis are present in >125 bacterial species, yet little is known about ... | 2017 | 28242707 |
| effect of prior receipt of antibiotics on the pathogen distribution and antibiotic resistance profile of key gram-negative pathogens among patients with hospital-onset urinary tract infections. | this retrospective cohort study characterized the impact of prior antibiotic exposure on distribution and nonsusceptibility profiles of gram-negative pathogens causing hospital-onset urinary tract infections (uti). | 2017 | 28241755 |
| synthesis, characterization and antibacterial studies of n-(benzothiazol-2-yl)-4-chlorobenzenesulphonamide and its neodymium(iii) and thallium(iii) complexes. | n-(benzothiazol-2-yl)-4-chlorobenzenesulphonamide (nbtcs) was synthesized by condensation reaction of 4-chlorobenzenesulphonyl chloride and 2-aminobenzothiazole in acetone under reflux. neodymium(iii) and thallium(iii) complexes of the ligand were also synthesized. both ligand and metal complexes were characterized using uv-vis, ir, ¹h- and (13)c-nmr spectroscopies, elemental analysis and molar conductance measurement. ir studies revealed that the ligand is tridentate and coordinates to the meta ... | 2017 | 28241439 |
| plesiomonas shigelloides periprosthetic knee infection after consumption of raw oysters. | periprosthetic infections are a leading cause of morbidity after total joint arthroplasty. common pathogens include staphylococcus aureus, streptococcus, enterococcus, escherichia coli, and pseudomonas aeruginosa. however, there are many cases in which rare bacteria are isolated. this case report describes a periprosthetic knee infection caused by plesiomonas shigelloides. in the united states, p shigelloides and 2 other vibrionaceae family members, vibrio vulnificus and vibrio parahaemolyticus, ... | 2017 | 28235124 |
| [spectrum of pathogens in postoperative complications of visceral surgery : the problem of multidrug resistance]. | in general surgery the etiology of surgical site infections has not significantly changed over the last 30 years. gram-positive bacteria, e.g. coagulase negative staphylococci (cns), staphylococcus aureus and enterococcus spp. as well as gram-negative bacteria, e.g. escherichia coli, enterobacter spp., klebsiella spp. and pseudomonas aeruginosa, are the most common findings. although in general surgery 10% of the s. aureus causing postoperative wound infections were methicillin resistant (mrsa), ... | 2017 | 28229205 |
| identification and characterization of a novel multifunctional placenta specific protein 8 in dugesia japonica. | placenta specific protein 8 (plac8) has been well studied in vertebrates, yet little is known in invertebrates. in this study, a novel plac8 from the planarian dugesia japonica was identified and its functions in immune responses and development were characterized. our results show that djplac8 was expressed in the pharynx, epidermis and intestine of intact adult planarian. the expression of djplac8 increased significantly upon lipopolysaccharide (lps) challenge, and inhibited the growth of the ... | 2017 | 28219778 |
| phytochemical screening and evaluation of in vitro antioxidant and antimicrobial activities of the indigenous medicinal plant albizia odoratissima. | albizia odoratissima (l. f.) benth has been used in indian folk medicine to treat numerous inflammatory pathologies, such as leprosy, ulcers, burns and asthma. | 2017 | 28219296 |
| comparison between flow cytometry and traditional culture methods for efficacy assessment of six disinfectant agents against nosocomial bacterial species. | the present study was undertaken to compare the use of flow cytometry (fcm) and traditional culture methods for efficacy assessment of six disinfectants used in quebec hospitals including: two quaternary ammonium-based, two activated hydrogen peroxide-based, one phenol-based, and one sodium hypochlorite-based. four nosocomial bacterial species, escherichia coli, staphylococcus aureus, pseudomonas aeruginosa, and vancomycin-resistant enterococci faecalis, were exposed to minimum lethal concentrat ... | 2017 | 28217115 |
| is surveillance for colonization of carbapenem-resistant gram-negative bacteria important in adult bone marrow transplantation units? | the aim of this study was to investigate the rate of carbapenem-resistant gram-negative bacilli (crgnb) colonization and to analyze the risk factors associated with crgnb colonization. | 2017 | 28214159 |