Publications

[critical approach to antibiotic therapy in lyme disease].		2015	8560838
[prevention of lyme disease].		2015	8560863
[clinical characteristics of lyme disease].	clinical characteristics of lyme disease were analysed in 22 patients. erythema migrans was found in 20 (91%), arthralgia in 18 (81%), neuralgia in 8 (36%), encephalitis in 3 (13%), carditis in 2 (9%) and arthritis in 2 (9%) patients. the positive antibody titer was found in 14 (63%) patients. favourable effects of antibiotic therapy was achieved in all patients. erythema migrans has been manifested up to 12 days after tick sting and arthralgia, arthritis, neuralgia, hepatitis and chronic dermat ...	2015	8273306
[lyme disease in children].	in the recent years the number of diagnosed cases of lyme disease has tended to increase. this is due to the possibility of serological examinations. between 1992-95 at the neurological department of 2nd chair of pediatrics silesian medical academy in katowice 7 children with lyme disease were hospitalized. the authors analysed the clinical course, important laboratory and serological data and treatment effects.	2015	9770690
poly-ticks: blue state versus red state for lyme disease.		2015	15664208
[lyme disease].		2015	2131499
lower incidence of peripheral catheter complications by the use of elastomeric hydrogel catheters in home intravenous therapy patients.	a prospective study was conducted to compare the performance of a nonconventional short peripheral catheter made of elastomeric hydrogel material with that of the conventional short peripheral catheters used to administer intravenous therapy to patients before this study was undertaken. the catheters were inserted in home care patients, primarily diagnosed with lyme disease, for the delivery of i.v. antibiotic therapy. the study results showed that the institutional 48-to-72-hour removal policy ...	2015	1748908
script concordance testing: assessing residents' clinical decision-making skills for infant lumbar punctures.	residents must learn which infants require a lumbar puncture (lp), a clinical decision-making skill (cdms) difficult to evaluate because of considerable practice variation. the authors created an assessment model of the cdms to determine when an lp is indicated, taking practice variation into account. the objective was to detect whether script concordance testing (sct) could measure cdms competency among residents for performing infant lps.	2014	24280838
potential misdiagnoses of bell's palsy in the emergency department.	we evaluate the incidence of potentially incorrect emergency department (ed) diagnoses of bell's palsy and identify factors associated with identification of a serious alternative diagnosis on follow-up.	2014	23891413
lyme disease or a complication of delusional parasitosis?		2014	23847121
tick-borne diseases in the south-east need human studies: lyme disease, stari and beyond.		2014	23356459
lyme disease.		2014	25073388
lyme arthritis of the pediatric lower extremity in the setting of polyarticular disease.	lyme arthritis can be readily treated with use of oral antibiotics without any need for surgery. in lyme-endemic areas, differentiating between lyme arthritis and septic arthritis can be difficult. laboratory testing for lyme disease often results in a delay in diagnosis because many labs batch-test lyme specimens only two times per week due to lack of equipment or increased expense. delayed diagnosis can lead to unneeded surgery in cases in which the surgeon indicates the patient for a joint ir ...	2014	25052528
lyme disease: a review of its epidemiology, evaluation, and treatment.	lyme disease, a tick-borne illness transmitted to humans, has become increasingly recognized.	2014	25016354
babesiosis in pregnancy.	babesiosis is an emerging infectious disease caused by a tick-borne parasite that infects red blood cells. pregnancy is a relatively immunocompromised state that can underlie severe manifestations of parasitic disease.	2014	25004307
when is a parasite not a parasite? effects of larval tick burdens on white-footed mouse survival.	many animal species can carry considerable burdens of ectoparasites: parasites living on the outside of a host's body. ectoparasite infestation can decrease host survival, but the magnitude and even direction of survival effects can vary depending on the type of ectoparasite and the nature and duration of the association. when ectoparasites also serve as vectors of pathogens, the effects of ectoparasite infestation on host survival have the potential to alter disease dynamics by regulating host ...	2014	25000767
the association of lyme disease with loss of sexual libido and the role of urinary bladder detrusor dysfunction.	the primary aim was to carry out a pilot study to compare the loss of sexual libido between a group of lyme disease patients and a group of matched controls. the secondary aim was to evaluate whether loss of libido in lyme disease patients is associated with urinary bladder detrusor dysfunction.	2014	24987563
respiratory modulation of cardiac vagal tone in lyme disease.	to conduct the first systematic test of the hypothesis that modulation of cardiac vagal tone is impaired in lyme disease.	2014	24976922
genomic resources notes accepted 1 april 2014 - 31 may 2014.	this article documents the public availability of a global transcriptome comparison between lyme disease tick vectors, ixodes scapularis and ixodes ricinus.	2014	24976445
new insights into stages of lyme disease symptoms from a novel hospital-based registry.	western connecticut health network created the lyme disease registry in response to the community's request and clinical need for more lyme disease research. the registry includes acute, recovered, and persistently symptomatic patients to better define the different stages of the disease. the design of the registry was guided by community and clinician input through a community-based participatory research process.	2014	24970880
[lyme disease].		2014	24940589
the geographic distribution of incident lyme disease among active component service members stationed in the continental united states, 2004-2013.		2014	24885878
population genetic structure of the lyme disease vector ixodes scapularis at an apparent spatial expansion front.	modeling and empirical evidence suggests that lyme disease is undergoing geographic expansion from principal foci in the midwestern and northeastern united states. virginia is at the southern edge of the current expansion zone and has seen dramatic rise in human lyme disease cases since 2007, potentially owing to a recent increase in vector abundance. ixodes scapularis is known throughout the eastern us but behavioral or physiological variation between northern and southern lineages might lead n ...	2014	24882702
third-degree heart block associated with lyme carditis: review of published cases.	lyme carditis is an uncommon manifestation of lyme disease that most commonly involves some degree of atrioventricular conduction blockade. third-degree conduction block is the most severe form and can be fatal if untreated. systematic review of the medical literature identified 45 published cases of third-degree conduction block associated with lyme carditis in the united states. median patient age was 32 years, 84% of patients were male, and 39% required temporary pacing. recognizing patient g ...	2014	24879781
lyme disease.		2014	24853157
case report of rare chronic myelogenous leukemia related multibacterial splenic abscess presenting with scrotal swelling.	splenic abscesses associated with leukemia are rare. most reported cases of splenic abscesses occur after chemotherapy and are related to the immunosuppressive effects of the chemotherapy. their etiology is most frequently fungal.	2014	25460444
hyperosmia in lyme disease.	neurological involvement in lyme disease has been reported to include meningitis, cranial neuropathy and radiculoneuritis. while it is known that in some cases of asceptic meningitis patients may develop hyperosmia, the association between hyperosmia and lyme disease has not previously been studied. objective to carry out the first systematic study to ascertain whether hyperosmia is also a feature of lyme disease. method a questionnaire regarding abnormal sensory sensitivity in respect of the se ...	2014	25098475
when lyme disease lingers. study confirms what doctors shouldn't do to treat recurring symptoms.		2014	25097955
lyme neuroborreliosis: a diagnostic headache.		2014	25362084
notes from the field: update on lyme carditis, groups at high risk, and frequency of associated sudden cardiac death--united states.	on december 13, 2013, mmwr published a report describing three cases of sudden cardiac death associated with lyme carditis. state public health departments and cdc conducted a follow-up investigation to determine 1) whether carditis was disproportionately common among certain demographic groups of patients diagnosed with lyme disease, 2) the frequency of death among patients diagnosed with lyme disease and lyme carditis, and 3) whether any additional deaths potentially attributable to lyme cardi ...	2014	25356607
a concise critical analysis of serologic testing for the diagnosis of lyme disease.	diagnostic testing for lyme disease in the clinical setting primarily relies on assessment of serologic responses to infection, with the exception of the early localized phase of disease, in which the diagnosis must be made clinically, due to the recognized insensitivity of serologic testing at this phase of disease. for the diagnosis of early disseminated and late disease, the centers for disease control and prevention (cdc) recommends a two-tiered approach to testing consisting of initial igm ...	2014	25351855
disseminated lyme disease presenting with nonsexual acute genital ulcers.	nonsexual acute genital ulceration (nagu) is a rare vulvar skin condition typically affecting girls and young women, characterized by acute onset of singular or multiple painful vaginal ulcers. the etiology of this ulcerative dermatosis has not been identified, although it has been associated with systemic infections. to our knowledge, this is the first report of an association with lyme disease.	2014	25162635
taking lyme disease to heart. enjoy the great outdoors, but be on the lookout for disease-carrying pests.		2014	25151670
lyme disease in poland in 2012.	in poland registration of all cases of lyme disease is conducted by the epidemiological unit of national institute of public health - national institute of hygiene. most cases of lyme disease occur in the north- east region of poland; however, it is important to note that the disease is no longer solely a problem of this region of poland.	2014	25135514
lyme disease.		2014	25119623
lyme disease.		2014	25119622
the relationship between deer density, tick abundance, and human cases of lyme disease in a residential community.	white-tailed deer (odocoileus virginianus zimmerman), serve as the primary host for the adult blacklegged tick (ixodes scapularis say), the vector for lyme disease, human babesiosis, and human granulocytic anaplasmosis. our objective was to evaluate the degree of association between deer density, tick abundance, and human cases of lyme disease in one connecticut community over a 13-yr period. we surveyed 90-98% of all permanent residents in the community six times from 1995 to 2008 to document r ...	2014	25118409
natural foci diseases as a stable biological threat.	the key aspects of the natural foci of especially dangerous diseases as a type of biological threats are presented. approaches to epidemiological surveillance and control to the spread of the agents of especially dangerous diseases on endemic areas are described for zoonosis that has a medical value. the knowledge of specific design of tools for the implementation of epidemiological surveillance, monitoring and evaluation of natural foci diseases in developing countries is low; accordingly, litt ...	2014	25326726
homozygous hemoglobin s (hbss) presenting with bilateral facial nerve palsy: a case report.	bilateral facial nerve palsy is a relatively rare presentation and often points to a serious underlying medical condition. several studies have reported presentation of bilateral facial nerve palsy in association with lyme disease, guillain-barre syndrome, systemic lupus erythematosus, human immunodeficiency virus, sarcoidosis, diabetes and hanson disease. while unilateral facial nerve palsy is sometimes associated with hemiplegia in sickle cell patients, no case of bilateral facial nerve palsy ...	2014	25319400
[serological verification of tick-borne encephalitis cases in the altai republic].	serologic testing of lyme disease, human granulocytic anaplasmosis and human monocytotopic ehrlichiosis, showed the prevalence of these infections and the risk of mixed infection. the patients with tick-borne encephalitis were found to have its monoinfection and mixed infection in 66.1% and 33.9% of cases, respectively.	2014	25296419
[lyme disease: how widespread is the problem?].	lyme disease is the cause of a lot of anxiety and discussion. patients are demanding more preventive actions to avoid tick bites, and earlier and better diagnosis of lyme disease. however, only a minority of people bitten by a tick go on to develop lyme disease. although physician delay may lead to a late diagnosis of disseminated lyme disease, these patients are still treatable and even in bad cases, symptoms will subside within a few years. while we know that serious complications of late diss ...	2014	25248741
[combatting lyme disease].	the prevalence of ticks seems to have increased with time, and the number of patients with lyme disease in the netherlands is also increasing. lyme disease and other tick-transmitted diseases now attract a lot of attention. several national initiatives at different levels are now in progress, with the aim of suppressing lyme disease and providing better care for patients with indications of having these diseases. a more uniform approach between different treatment centres, joint research and fur ...	2014	25248736
[prevalence of lyme disease among forestry workers].	the aim of the study is to assess the incidence of lyme disease, established diagnosis based on medical history and clinical symptoms, serology, duration of exposure in the workplace and occupational disease certification among forestry workers in selected districts of the warmia and mazury region.	2014	25230562
bullous lyme disease.		2014	25219730
lyme disease and post-treatment lyme disease syndrome: the neglected disease in our own backyard.	a survey was developed to assess experience and opinions about lyme disease and post-treatment lyme disease syndrome (ptlds) among faculties in public health. no previous surveys of public health faculties have been found in the literature.	2014	25213101
ascending aortitis: a clinicopathological study of 21 cases in a series of 300 aortic repairs.	there are few single-institution clinicopathological series of aortitis. in this study, all ascending aneurysms were prospectively evaluated pathologically with ≥6 aortic sections over a 6-year period.of 300 ascending aortic resections, there were 21 cases of aortitis (7%), in 11 women and 10 men (mean 67, range 41-88 years). there were 19 patients with aneurysms, and two patients with sclerosing periaortitis, clinically suspected to have intramural haematoma. of the 19 patients with aneurysms ( ...	2014	24798167
feedback on difficulties raised by the interpretation of serological tests for the diagnosis of lyme disease.	we had for objectives: i) to evaluate the accuracy of serologic testing for lyme borreliosis performed in a private medical laboratory (pml); ii) to evaluate the impact of these tests on the practices of infectious diseases specialists (ids).	2014	24794819
lyme neuroborreliosis and dementia.	descriptions of lyme disease and dementia are rare.	2014	24762944
pathogenesis of post-lyme disease symptoms.		2014	24812298
choosing wisely: the american college of rheumatology's top 5 for pediatric rheumatology.	to create a pediatric rheumatology top 5 list as part of the american board of internal medicine foundation's choosing wisely campaign.	2014	24756998
the use of ivermectin to kill ixodes scapularis ticks feeding on humans.	the purpose of this study was to determine whether 400 µg/kg oral ivermectin is able to kill ixodes scapularis nymphs and adult female ticks feeding on humans.	2014	24411976
pharmacist initiation of postexposure doxycycline for lyme disease prophylaxis.	objectives to enhance public access to prophylaxis for lyme disease following an identified ixodes scapularis tick bite through pharmacist-initiated antibiotic therapy and to assess patient satisfaction with the pharmacy-based service provided. setting independent community pharmacy in charlestown, ri, from may to october 2012. practice description under a collaborative practice agreement, trained pharmacists at an independent pharmacy identified patients eligible for postexposure antibiotic pro ...	2014	24407743
lyme disease -induced polyradiculopathy mimicking amyotrophic lateral sclerosis.	to describe a case of predominantly motor polyradiculopathy secondary to lyme disease that can mimic motor neuron disease and has been rarely reported.	2014	24397499
synovial fluid findings in children with knee monoarthritis in lyme disease endemic areas.	although lyme and septic arthritis of the knee may have similar clinical presentations, septic arthritis requires prompt identification and treatment to avoid joint destruction. we sought to determine whether synovial fluid cell counts alone can discriminate between lyme, septic, and other inflammatory arthritis.	2014	24365728
lyme disease vaccination: safety first - author's reply.		2014	24355030
lyme disease vaccination: safety first - authors' reply.		2014	24355029
lyme disease vaccination: safety first.		2014	24355028
hyperbaric oxygen therapy as an effective adjunctive treatment for chronic lyme disease.	lyme disease is the most commonly reported vector-borne illness in the united states, but it is relatively rare in taiwan. lyme disease can be treated with antibiotic agents, but approximately 20% of these patients experience persistent or intermittent subjective symptoms, so-called chronic lyme disease (cld). the mechanisms of cld remain unclear and the symptoms related to cld are difficult to manage. hyperbaric oxygen therapy (hbot) was applied in cld therapy in the 1990s. however, reported in ...	2014	24726678
intermediate uveitis in children and young adults: differences in clinical course, associations and visual outcome.	intermediate uveitis (iu) is considered to carry a considerable risk for complications and visual loss. this study compares juvenile and adult onset iu with regard to visual loss and complications.	2014	24713505
[multiple erythema migrans and facial nerve paralysis: clinical manifestations of early disseminated lyme borreliosis].	lyme borreliosis is a common vector-borne disease in europe. the infection follows different stages with a broad variability of clinical symptoms and manifestations in different organs. a 49-year-old man presented with flu-like symptoms, facial nerve paralysis and multiple erythematous macular on his trunk and extremities. we diagnosed lyme disease (stage ii) with facial nerve paralysis and multiple erythema migrans. intravenous ceftriaxone led to complete healing of hissymptoms within 2 weeks.	2014	24700023
[lyme disease acrodermitis chronica atrophicans: misleading vascular signs].	lyme disease acrodermatitis chronica atrophicans is a tertiary form of lyme borrelliosis. it occurs at least six months, but also up to several years, after a tick bite. this rare condition is probably underestimated because of the difficult diagnosis. clinical presentations of acrodermatitis chronic atrophicans are quite variable depending upon the duration of the disease. complimentary explorations are difficult to interpret and rarely specific. only rare configurations allow formal diagnosis ...	2014	24698204
identifying erythema migrans rash in patients with lyme disease.		2014	24695559
oral doxycycline for lyme neuroborreliosis with symptoms of encephalitis, myelitis, vasculitis or intracranial hypertension.	the treatment recommendation for lyme neuroborreliosis with central nervous system (cns) symptoms is intravenous ceftriaxone, according to current american and european guidelines. for lyme neuroborreliosis with peripheral nervous system (pns) symptoms, treatment with intravenous ceftriaxone and oral doxycycline is considered equally effective. the purpose of this study was to evaluate the efficacy of oral doxycycline in the treatment of lyme neuroborreliosis with cns symptoms.	2014	24684211
lack of accurate information on the prevalence of lyme disease in the uk.		2014	24614077
chronic lyme disease: fact or fiction?		2014	24582003
apolipoprotein a-i at the interface of vascular inflammation and arthritis.		2014	24554604
common questions about bell palsy.	bell palsy is an acute affliction of the facial nerve, resulting in sudden paralysis or weakness of the muscles on one side of the face. testing patients with unilateral facial paralysis for diabetes mellitus or lyme disease is not routinely recommended. patients with lyme disease typically present with additional manifestations, such as arthritis, rash, or facial swelling. diabetes may be a comorbidity of bell palsy, but testing is not needed in the absence of other indications, such as hyperte ...	2014	24506123
statistical issues when searching for predictors of post-lyme disease symptoms.		2014	24470274
potential benefits of retreatment highlight the need for additional lyme disease research.		2014	24462019
appalachian trail hikers' ability to recognize lyme disease by visual stimulus photographs.	lyme disease is the most common vector-borne infectious disease in north america. with nearly 2,500 appalachian trail (at) hikers entering the endemic area for as long as 6 months, exposure to the disease is likely. the characteristic exanthem of erythema migrans (em) should be a trigger for seeking medical treatment, and its recognition in this relatively isolated environment is important.	2014	24433777
etiology, diagnosis, and management of facial palsy: 2000 patients at a facial nerve center.	to evaluate the range and incidence of facial palsy etiologies in cases presenting to a tertiary facial nerve center, and to review the broad and evolving spectrum of diagnostic and management approaches to the condition.	2014	24431233
diagnostic criteria of acute rheumatic fever.	acute rheumatic fever is an inflammatory sequela of group a streptococcal pharyngitis that affects multiple organ systems. the incidence of acute rheumatic fever has been declining even before the use of antibiotics became widespread, however the disease remains a significant cause of morbidity and mortality in children, particularly in developing countries and has been estimated to affect 19 per 100,000 children worldwide. acute rheumatic fever is a clinical diagnosis, and therefore subject to ...	2014	24424191
tick-borne illness in rhode island - how big a problem is it?	rhode island is a state with a high incidence of tick-borne diseases, specifically lyme disease. the ioxedes tick which serves as vector for the three most common tick infections is endemic in both the new england and mid-atlantic regions. however, differences in the density of infections exist within rhode island (ri), with the highest densities in the southern counties. tick-borne diseases can have varying presentations, as well as varied response to appropriate treatment leading to many quest ...	2014	25562059
images in emergency medicine. infant with rash. neonatal lyme disease.		2014	25669704
[lyme disease].		2014	25438433
evaluating the need for a specialist service on lyme disease in australia.		2014	25414457
lyme disease with effusion either in hip or knee in children from podlaskie region treated in clinic in 2004-2010.	lyme disease (lb) relatively commonly causes arthritis among patients, especially in lb endemic area. the aim of the study was to analyze the prevalence of lb in children with hip and knee effusion in the north eastern region of poland. conclusions from our study should justify the need of taking into account lb in the diagnosis of hip or knee effusion in children.	2014	25394303
[why is my foot swollen and red?].	we present the case of a 26 year old man reporting to the family doctor due to swelling and redness of the foot. after thrombosis and a tumorous mass could be excluded, the suspicion fell on an acrodermatitis chronica atrophican which could be confirmed by laboratory tests. during therapy there was a significant regression of the cutaneous lesion. the treatment of the lyme disease was taken over by the casualty insurer.	2014	25391746
lyme disease in pregnancy: a new jersey medical advisory.		2014	25375870
case of tick-associated rash illness caused by amblyomma testudinarium.	we report a case of tick-associated rash illness (tari), a new clinical entity of erythema migrans associated with a tick bite without infection of lyme borreliosis agent. the patient, a 53-year-old man, went hiking in a mountainous area of minoh city, osaka prefecture in october 2012. an erythematous macule with itching and a biting tick was found on his left thigh 2 days later, which gradually expanded. on the first visit to our department at the fifth day after hiking, an erythematous macule ...	2014	25156744
of mice and men: lyme disease and biodiversity.	the current rapid rate of species extinction and loss of biodiversity occurring throughout the world has the potential to exact far-reaching adverse impacts on human health in many ways, including increasing the risk of infectious disease transmission. here, we use lyme disease as a model to illustrate how loss of biodiversity in the community of vertebrates may lead to increased transmission of zoonotic pathogens in humans. we also illustrate how preserving biodiversity has the potential to red ...	2014	25544324
long-term assessment of fibromyalgia in patients with culture-confirmed lyme disease.	background: fibromyalgia occurs in 2% to 8% of the general population. one of the triggers may be lyme disease. methods: patients with culture-confirmed lyme disease who originally presented with erythema migrans have been evaluated annually in a prospective study to determine their long-term outcome. in 2011-2013, subjects were evaluated for fibromyalgia by interview and tender point examination. results: 100 subjects were assessed, 52% of whom were male; the mean age was 64.9 years (median 64 ...	2014	25470117
a qualitative approach to understanding patients' diagnosis of lyme disease.	the purpose of this study was to explore the lived experience of becoming diagnosed with lyme disease.	2014	16460417
molecular identification and phylogeny of dermacentor nuttalli (acari: ixodidae).	dermacentor nuttalli is an epidemiologically important tick in palearctic asia which transmits several infectious diseases including tularemia, north asian tick-borne rickettsiosis, lyme disease and tick-borne encephalitis. the genetic specificity and phylogeny of d. nuttalli from four geographic localities in eastern siberia were characterized using the mitochondrial (mt) 16s ribosomal rna (rrna) gene and internal transcribed spacer 2 (its2). low genetic diversity was observed in the population ...	2014	24604384
culture and identification of borrelia spirochetes in human vaginal and seminal secretions.	background: recent reports indicate that more than 300,000 cases of lyme disease are diagnosed yearly in the usa. preliminary clinical, epidemiological and immunological studies suggest that infection with the lyme disease spirochete borrelia burgdorferi (bb) could be transferred from person to person via intimate human contact without a tick vector. failure to detect viable borrelia spirochetes in vaginal and seminal secretions would argue against this hypothesis. methods: patients with and wit ...	2014	28690828
opsoclonus associated with salmonellosis in a 6-week-old infant.	a 6-week-old male infant presented with 2 days of fever, emesis, and diarrhea, associated with episodic and chaotic rapid eye movements, determined to be opsoclonus. an electroencephalogram (eeg) obtained during the events was normal. he was treated empirically for meningitis, and an initial workup for neuroblastoma including urine homovanillic acid and vanillylmandelic acid levels, abdominal ultrasonography, and computed tomography (ct) of the chest, abdomen, and pelvis was negative. stool and ...	2014	23456533
rational design of antigens to improve the serodiagnosis of tick-borne borreliosis in central regions of russia.	tick-borne borreliosis (lyme disease-ld) is caused by pathogenic borrelia spirochetes that is transmitted through bite of ixodes ticks to humans and animals. in the russian federation, borreliosis registered with an index of 6-7 per 100,000 people annually. in reality, ld morbidity in russia is much higher because russian strains develop less erythematous rashes compared to north american strains, thus missed by physicians in most of the early cases, and current serology tests have insufficient ...	2014	24619615
seroprevalence of borrelia burgdorferi sensu lato and tick-borne encephalitis virus in zoo animal species in the czech republic.	this study was conducted to evaluate the prevalence of antibodies against borrelia bugdorferi (bb) s.l. and tick-borne encephalitis virus (tbev) in zoo animals in the czech republic. we collected 133 serum samples from 69 animal species from 5 zoos located in different parts of the country. the samples were obtained from even-toed ungulates (n=78; 42 species), odd-toed ungulates (n=32; 11 species), carnivores (n=13; 9 species), primates (n=2, 2 species), birds (n=3; 2 species), and reptiles (n=5 ...	2014	24889036
minimal role of eastern fence lizards in borrelia burgdorferi transmission in central new jersey oak/pine woodlands.	the eastern fence lizard, sceloporus undulatus , is widely distributed in eastern and central north america, ranging through areas with high levels of lyme disease, as well as areas where lyme disease is rare or absent. we studied the potential role of s. undulatus in transmission dynamics of lyme spirochetes by sampling ticks from a variety of natural hosts at field sites in central new jersey, and by testing the reservoir competence of s. undulatus for borrelia burgdorferi in the laboratory. t ...	2014	24871138
[lyme disease].	lyme disease (ld) is a worldwide-distributed multisystemic process caused by borrelia burgdorferi sensu lato (s.l.) and transmitted by hard ticks. in fact, it is the most common tick-borne infectious disease in the northern hemisphere. in spain it is transmitted by ixodes ricinus ticks and borrelia garinii is the genoespecies of b. burgdorferi s.l. mostly involved in our area. ld is known as "the last great imitator" due to the broad clinical spectrum that may cause. except in the case of erythe ...	2014	24630582
why are there several species of borrelia burgdorferi sensu lato detected in dogs and humans?	borrelia burgdorferi sensu lato is a group of spirochete bacteria species some of which cause borreliosis in humans and dogs. humans and dogs are susceptible to illness from many of the same tick-borne pathogens, including b. burgdorferi s.l. (bbsl). little is known about the pathogenic role of the species of bbsl in canines. the molecular methods which detect and amplify the dna of borreliae and allow differentiating borreliae species or strains have not been used in canine diagnostics yet. unt ...	2014	24613432
performance of a multiplexed serological microarray for the detection of antibodies against central nervous system pathogens.	central nervous system (cns) infections have multiple potential causative agents for which simultaneous pathogen screening can provide a useful tool. this study evaluated a multiplexed microarray for the simultaneous detection of antibodies against cns pathogens. the performance of selected microarray antigens for the detection of igg antibodies against herpes simplex virus 1 and 2 (hsv-1 and hsv-2), varicella-zoster virus (vzv), adenovirus, mycoplasma pneumoniae and borrelia burgdorferi sensu l ...	2014	24594410
lyme disease: neurology, neurobiology, and behavior.	the lyme disease controversy can be largely linked to the misconception that neurobehavioral effects of illness constitute evidence of nervous system infection. appropriate differentiation between neuroborreliosis (nervous system borrelia burgdorferi infection) and lyme encephalopathy (altered nervous system function in individuals with systemic but not nervous system infection)-or encephalopathies of other etiologies-would lessen the controversy considerably, as the attribution of nonspecific s ...	2014	24571864
outer surface proteins of borrelia: peerless immune evasion tools.	lyme borreliosis (lb), caused by borrelia burgdorferi (b.b.), is the most frequently diagnosed tick-borne zoonosis in temperate zones of the northern hemisphere. borrelia is unique among bacteria in its ability to express a wide variety of lipoproteins on its surface, which play an essential role in pathogenesis. surface proteins of spirochetes are important virulence determinants, immune evasion molecules and adaptation factors in the transmission and interaction with host tissues. vast diversi ...	2014	24555888
survey of veterinarians' perceptions of borreliosis in north carolina.	objective--to evaluate the practices and perceptions of veterinarians in north carolina regarding borreliosis in dogs in various geographic regions of the state. design--cross-sectional survey. sample--data from 208 completed surveys. procedures--surveys were distributed to veterinary clinics throughout north carolina. descriptive statistics were used to summarize perceptions pertaining to borreliosis among dogs in north carolina. results--a significantly higher proportion of responding veterina ...	2014	24548235
lack of igg antibody seropositivity to borrelia burgdorferi in patients with parry-romberg syndrome and linear morphea en coup de sabre in mexico.	progressive hemifacial atrophy or parry-romberg syndrome (prs) is a rare, acquired, progressive dysplasia of subcutaneous tissue and bone characterized by unilateral facial involvement. its etiology is unknown, but theories about its pathogenesis include infectious, degenerative, autoimmune, and traumatic causes among others. the causal relationship of prs and linear morphea en coup de sabre (lmcs) with borrelia burgdorferi infection remains controversial. our goal was to serologically determine ...	2014	24527729
the lymphocyte transformation test for the diagnosis of lyme borreliosis has currently not been shown to be clinically useful.		2014	24520912
lumbosacral multiradiculopathy responsive to antibiotic therapy: description of four patients with lumbar spondylosis and a superimposed lyme disease.	lyme disease is a diffuse zoonosis caused by spirochaetes of the borrelia burgdorferi species complex. neurological manifestations of the disease, involving central or peripheral nervous system, are common. this study describes four consecutive patients with an mri-proven lumbosacral spondylosis, who complained of progressive worsening of symptoms in the last months in which serological evaluation suggested a superimposed b. burgdorferi infection. four patients, all from the lazio region, were a ...	2014	24515913
[lyme disease: an update].	lyme disease is an emerging infection caused by the spirochete borrelia burgdorferi. it is the most common vector-borne disease in the usa and europe, and it is transmitted to humans through the bite of ticks of the genus ixodes. its animal reservoirs are the white-tailed deer, the white-footed mouse, and other small mammals. it is considered the new "great imitator", with its diagnosis being a major challenge. traditionally it is divided into four stages, early localized disease, early dissemin ...	2014	24481435
genotyping of borrelia from formalin-fixed paraffin-embedded skin biopsies of cutaneous borreliosis and tick bite reactions by assays targeting the intergenic spacer region, ospa and ospc genes.	lyme borreliosis has a broad spectrum of clinical presentations involving the skin, joints and nervous system. the variable manifestations have been attributed to different borrelia genospecies but genotyping required culture or fresh tissue. however, in dermatology practice, formalin-fixed paraffin-embedded biopsies are used for dermatopathological examination. polymerase chain reaction (pcr) for borrelia burgdorferi sensu latu has been established on such specimens, but studies attempting geno ...	2014	24471698