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cross-reactivity to borrelia burgdorferi proteins in serum samples from residents of a tropical country nonendemic for lyme disease.reports of lyme disease from areas where the disease is not endemic have increased. eighty-six human serum samples from papua new guinea (nonendemic for lyme disease) were examined for the presence of igg antibodies that recognize borrelia burgdorferi antigens, using the currently recommended two-tiered system of analysis (sensitive elisa with western blot). the percentage of positive tests dropped from 50% to 10% when individual negative controls were included in the two-tiered analysis. positi ...19979203675
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