Publications

resurgence of cutaneous leishmaniasis in israel, 2001-2012.	cutaneous leishmaniasis has long been endemic in israel. after a 15-year period of moderate illness rates, reported incidence increased from 0.4 cases per 100,000 population in 2001 to 4.4 cases per 100,000 population in 2012, and the disease emerged in areas where its presence had previously been minimal. we analyzed all cases reported to the national surveillance system and found that outbreak patterns revealed an expansion of leishmania major infections over large areas in the southern part o ...	0	25271882
leishmaniasis in israel: reservoir hosts, sandfly vectors and leishmanial strains in the negev, central arava and along the dead sea.	the reservoir animals, sandfly vectors and strains of leishmania from foci in the southern region of israel were studied. the rodent host species are: psammomys obesus, meriones crassus and probably nesokia indica. the vector species are phlebotomus papatasi, which were caught at all collecting sites and ph. sergenti, which were collected in the area of the dead sea and in the central arava. strains of leishmania major isolated from rodents, vectors and man were serologically and enzymologically ...	1984	6385358
keziot--a new endemic site of cutaneous leishmaniasis in israel. an epidemiological and clinical study of a non-immune population entering an endemic area.	in this study we describe a new endemic focus of cutaneous leishmaniasis at keziot in southern israel, and the pattern of the disease among a group of soldiers newly based in the area. interviews and physical examinations were conducted on 296 soldiers, and 247 were subjected to a leishmanin skin test. positive tests were recorded in 18% of the soldiers; in 16% of them keziot was identified as the area where the infection was acquired. positive skin tests were found among 93% and 41% of soldiers ...	1985	4095766
outbreak of cutaneous leishmaniasis in northern israel.	this study describes a new focus of cutaneous leishmaniasis (cl) due to leishmania tropica, in the galilee region of northern israel. thirty-three cases from 4 villages (northern part) and from the city of tiberias (southern part) have been clinically diagnosed since 1996. parasites from 13 patients and from 6 sand flies were characterized by isoenzyme electrophoresis, 2 immunological methods, and 3 polymerase chain reaction (pcr)-based methods. isolates from the northern part were antigenically ...	2003	14513429
the flow-cytometry-based evaluation of cellular immunity in cases of cutaneous leishmaniasis and healthy controls from the endemic area in southern israel.	only limited data are available on the early immunological events associated with human cutaneous leishmaniasis (cl). in this study, peripheral-blood mononuclear cells were obtained from 66 individuals (34 patients with cutaneous lesions and 32 apparently healthy controls) who had each spent no more than 3 months in the endemic region of qetzioth, in southern israel. these cells' responses to leishmania major antigen were then explored, by the flow-cytometry-based evaluation of blast transformat ...	2006	16417710
[cutaneous leishmaniasis treated with ambisome (liposomal amphotericin b)].	cutaneous leishmaniasis, caused mainly by leishmania major, is endemic in southern israel. it is characterized by multiple skin lesions on the skin's patient. the treatment often includes only topical treatment, and treatment failures are not uncommon. liposomal amphotericin b, a drug approved for visceral leishmaniasis treatment, has rarely been used for the cutaneous disease, especially for old world cutaneous leishmaniasis. we report a 1-year-old patient with multiple skin lesions, diagnosed ...	2012	23350289
a newly emerged cutaneous leishmaniasis focus in northern israel and two new reservoir hosts of leishmania major.	in 2006/7, 18 cases of cutaneous leishmaniasis (cl) were reported for the first time from sde eliyahu (pop. 650), a village in the beit she'an valley of israel. between 2007-2011, a further 88 cl cases were diagnosed bringing the total to 106 (16.3% of the population of sde eliyahu). the majority of cases resided in the south-western part of the village along the perimeter fence. the causative parasite was identified as leishmania major yakimoff & schokhor, 1914 (kinetoplastida: trypanosomatidae ...	2013	23437408
dramatic increase in laboratory-diagnosed human cutaneous leishmaniasis cases in southern israel, 2007-2013.	cutaneous leishmaniasis (cl) is an endemic zoonosis in southern israel. in recent years, substantial urbanization has been taking place in this region. the introduction of populations into endemic foci was previously reported to facilitate human cl outbreaks. our aim was to describe a continuous cl outbreak in southern israel, through laboratory reports of cl diagnosis.	2015	25622937
cutaneous leishmaniasis caused by leishmania infantum in southern israel.	cutaneous leishmaniasis (cl) caused by leishmania major is common in southern israel, while leishmania infantum (sub-strain of l. donovani, causing zoonotic visceral leishmaniasis) infections were rarely reported in israel and only in other regions. we report the first case of l. infantum infection in southern israel, presented atypically as cl in an immunosuppressed 47-year old male. the patient was treated with liposomal amphotericin-b and recovered, without extra-cutaneous complications. diag ...	2016	27787222