Publications

comparison of fluoroquinolone resistance genes of salmonella enterica serovar choleraesuis isolates in japan and taiwan.		2004	15623959
detection of mutations in the gyra gene and class i integron from quinolone-resistant salmonella enterica serovar choleraesuis isolates in taiwan.	the quinolone resistance-determining regions (qrdrs) of the gyra gene of quinolone-resistant salmonella enterica serovar choleraesuis isolates were sequenced. four types of point mutation, ser-83-to-phe (tcc --> ttc), ser-83-to-tyr (tcc --> tac), asp-87-to-gly (gac --> ggc), and asp-87-to-asn (gac --> aac), were found. pcr-rflp and mas-touch down pcr were performed on fifty swine clinical isolates of s. enterica serovar choleraesuis (nalr) collected during 1997-2002. the analysis indicated seven ...	2004	15145503
epidemiologic relationship between fluoroquinolone-resistant salmonella enterica serovar choleraesuis strains isolated from humans and pigs in taiwan (1997 to 2002).	the emergence of ciprofloxacin-resistant salmonella enterica serovar choleraesuis in recent years has become an important public health issue in taiwan. the resistant strains that cause human infections are considered to be from pigs. in this study, we characterized 157 swine and 42 human salmonella serovar choleraesuis isolates by pulsed-field gel electrophoresis (pfge) and drug susceptibility testing to investigate the epidemiologic relationship among the isolates. by pfge analyses, two major ...	2005	15956400
characterisation of antimicrobial resistance patterns and class 1 integrons among escherichia coli and salmonella enterica serovar choleraesuis strains isolated from humans and swine in taiwan.	escherichia coli isolates from humans (n=110) and swine (n=61) and salmonella enterica serovar choleraesuis isolates (n=95) from swine in southern taiwan were characterised for antimicrobial resistance patterns and class 1 integrons. all e. coli isolates and s. choleraesuis isolates were multidrug resistant and demonstrated high resistance to beta-lactams, aminoglycosides, tetracycline, sulfonamides, spectinomycin, chloramphenicol and nalidixic acid. by polymerase chain reaction and dna sequenci ...	2006	16621462
consumption of groundwater as an independent risk factor of salmonella choleraesuis infection: a case-control study in taiwan.	infection with salmonella enterica serovar choleraesuis (s. choleraesuis) in humans can be considered as an endemic disease in certain regions of taiwan, and the number of cases has increased in recent years. the goal of the case-control study discussed in this article was to identify the possible demographic and environmental risk factors associated with s. choleraesuis infection in taiwan. during the period of december 2005 to march 2007, the case-control study was conducted in human patients ...	2009	20063610
molecular characterisation of class 1 integrons in salmonella enterica serovar choleraesuis isolates from southern taiwan.	integron-mediated multidrug resistance in salmonellaenterica serovar choleraesuis poses a major concern in human salmonellosis in taiwan. in this study, 71 strains of s. choleraesuis harbouring a class 1 integron from humans and animals were characterised for detection of integrons, gene cassettes and the spvc virulence gene using molecular genetic techniques. all 71 strains tested were negative for class 2 and 3 integrons. fifty-eight (81.7%) of the isolates harboured a class 1 integron with di ...	2009	19084383
Reduction of Salmonella enterica serovar Choleraesuis carrying large virulence plasmids after the foot and mouth disease outbreak in swine in southern Taiwan, and their independent evolution in human and pig.	BACKGROUND/PURPOSE: Salmonella enterica serovar Choleraesuis (S. Choleraesuis) is a highly invasive zoonotic pathogen that causes bacteremia in humans and pigs. The prevalence of S. Choleraesuis in man has gradually decreased since the outbreak of foot and mouth disease in pigs in 1997 in southern Taiwan. The goal of this study was to investigate the change in prevalence of S. Choleraesuis carrying the virulence plasmid (pSCV) in human and swine isolates collected in 1995-2005 and characterize t ...	2011	22209685
decline in ciprofloxacin-resistant salmonella enterica serovar choleraesuis in taiwan, 2001-2011.		2013	23390070