Publications

the prevalence of neutralizing antibodies against aav serotype 1 in healthy subjects in china: implications for gene therapy and vaccines using aav1 vector.	recombinant adeno-associated virus serotype 1 (aav1) has attracted tremendous interest as a promising vector for gene therapy and vaccine applications. however, the presence of aav1 neutralizing antibodies as a consequence of exposure to wild type aav1 can limit significantly effective gene transfer for biologics based aav1 vector. prior studies have reported that a prevalence of aav1 neutralizing antibodies ranged from 10% to 50% in different countries around the world, and up to 79% in dutch s ...	2013	23852678
novel avian-origin influenza a (h7n9) virus attachment to the respiratory tract of five animal models.	we determined the pattern of attachment of the avian-origin h7n9 influenza viruses a/anhui/1/2013 and a/shanghai/1/2013 to the respiratory tract in ferrets, macaques, mice, pigs, and guinea pigs and compared it to that in humans. the h7n9 attachment pattern in macaques, mice, and to a lesser extent pigs and guinea pigs resembled that in humans more closely than the attachment pattern in ferrets. this information contributes to our knowledge of the different animal models for influenza.	2014	24478425