Publications

complete genome sequence of bat coronavirus hku2 from chinese horseshoe bats revealed a much smaller spike gene with a different evolutionary lineage from the rest of the genome.	apart from bat-sars-cov, we have identified a novel group 1 coronavirus, bat-cov hku2, in rhinolophus sinicus (chinese horseshoe bats). since it has been suggested that the receptor-binding motif (rbm) of sars-cov may have been acquired from a group 1 coronavirus, we conducted a surveillance study and identified bat-sars-cov and bat-cov hku2 in 8.7% and 7.5% respectively of r. sinicus in hong kong and guangdong. complete genome sequencing of four strains of bat-cov hku2 revealed the smallest cor ...	2007	17617433
novel bat alphacoronaviruses in southern china support chinese horseshoe bats as an important reservoir for potential novel coronaviruses.	while bats are increasingly recognized as a source of coronavirus epidemics, the diversity and emergence potential of bat coronaviruses remains to be fully understood. among 1779 bat samples collected in china, diverse coronaviruses were detected in 32 samples from five different bat species by rt-pcr. two novel alphacoronaviruses, rhinolophus sinicus bat coronavirus hku32 (rs-batcov hku32) and tylonycteris robustula bat coronavirus hku33 (tr-batcov hku33), were discovered from chinese horseshoe ...	2019	31067830
genetic evolution analysis of 2019 novel coronavirus and coronavirus from other species.	the corona virus disease 2019 (covid-19) caused by severe acute respiratory syndrome coronavirus 2 (sars-cov-2) is a public health emergency of international concern. however, so far, there are still controversies about the source of the virus and its intermediate host. here, we found the novel coronavirus was closely related to coronaviruses derived from five wild animals, including paguma larvata, paradoxurus hermaphroditus, civet, aselliscus stoliczkanus and rhinolophus sinicus, and was in th ...	2020	32169673