Publications

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multistate outbreak of monkeypox--illinois, indiana, and wisconsin, 2003.cdc has received reports of patients with a febrile rash illness who had close contact with pet prairie dogs and other animals. the marshfield clinic, marshfield, wisconsin, identified a virus morphologically consistent with a poxvirus by electron microscopy of skin lesion tissue from a patient, lymph node tissue from the patient's pet prairie dog, and isolates of virus from culture of these tissues. additional laboratory testing at cdc indicated that the causative agent is a monkeypox virus, a ...200312803191
multiple diagnostic techniques identify previously vaccinated individuals with protective immunity against monkeypox.approximately 50% of the us population received smallpox vaccinations before routine immunization ceased in 1972 for civilians and in 1990 for military personnel. several studies have shown long-term immunity after smallpox vaccination, but skepticism remains as to whether this will translate into full protection against the onset of orthopoxvirus-induced disease. the us monkeypox outbreak of 2003 provided the opportunity to examine this issue. using independent and internally validated diagnost ...200516086024
retrospective analysis of monkeypox infection.serologic cross-reactivity between orthopoxviruses is a substantial barrier to laboratory diagnosis of specific orthopoxvirus infections and epidemiologic characterization of disease outbreaks. historically, time-consuming and labor-intensive strategies such as cross-adsorbed neutralization assays, immunofluorescence assays, and hemagglutination-inhibition assays have been used to identify orthopoxvirus infections. we used cross-adsorption to develop a simple and quantitative postadsorption elis ...200818394277
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