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dogs, distemper and osteitis deformans: a further epidemiological study.there is extensive evidence linking paramyxoviruses, notably measles and respiratory syncytial virus, with paget's disease of bone. the epidemiology of paget's disease does not fit with that of known human paramyxovirus infections and it is possible that the disease is a zoonosis with domestic animals acting as host. canine distemper, a paramyxovirus of the morbillovirus family (closely related to measles) is therefore a potential candidate. we have surveyed previous pet ownership in 150 paget's ...19902268748
[comparative pathology of gastrointestinal cancer in the dog and cat]. 19675626321
observations on the incidence of toxocara and toxascaris in dogs and cats from the london area. 19655886486
infection with animal helminths as a factor in causing poliomyelitis and epilepsy. 19665949491
pasteurella septica infection in respiratory disease. 19676067792
oil pollution of animals and birds in south-west england. 19676068116
spondylosis deformans (vertebral osteophytosis) in the dog. a radiographic study from england, sweden and u.s.a. 19676068839
in-vitro culture of human hydatid material. 19806101653
some excerpts from the writings of stephen hales, with comment on their relation to the concept of heart failure. 19836340260
equine anaesthesia: discovery and rediscovery. 19836349982
historical review of pharyngo-oesophageal reconstruction after resection for carcinoma of pharynx and cervical oesophagus. 19836357571
john hunter's application of science to surgery. 19846362538
hepatorenal toxicity in a dog following immersion in rutland water. 19902275081
tumours in captive wild animals: some observations and comparisons. 19694950344
upper digestive tract neoplasia in the cat (a comparative study).along with man and the dog, the cat is predisposed to a variety of neoplasia of the upper digestive tract. the present paper is an account of the case material seen in a surgical pathology department during a 24-year period, with comments on the comparative aspects where relevant.19846512394
the future control of tuberculosis. 19674962168
poisoning at rutland water. 19892510394
obesity in pet dogs. 19705465678
liver disease in skye terriers. 19846702081
angiostrongylus vasorum: transmission in south east england. 19902368287
autotransfusion: intraoperative scavenging. 19826757147
campylobacter fetus subspecies jejuni: the need for surveillance. 19806768813
toxocaral and toxoplasmal antibodies in cat breeders and in icelanders exposed to cats but not to dogs. 19826800442
sydney ringer and the origins of cardioplegia. 19863526594
transplantation--a perspective. 19807010715
patterns of infection with giardia in dogs in london. 19892609377
early intravenous anesthesia: an eyewitness account.descriptions of the earliest iv injections of various substances by individuals who actually witnessed the experiments in 1656 are presented. of particular interest is an apparently overlooked account of an experiment in which opium was administered intravenously to a dog many years before 1674 as related by the physician and anatomist thomas willis. he does not identify the precise date nor the experimenters. however, at the time of this event willis would have been at oxford. there he was a ve ...19902404427
prevalence of fleas on dogs and cats in an area of central london. 19817193779
'slugs and snails and puppy-dog tails'-children's ideas about the inside of their bodies.twenty-six children at each of four age-levels (6, 8, 10 and 12 years) were asked to draw the inside of their bodies and to answer some questions on body organization and function. although knowledge increased with age, it was consistently below that reported in earlier american studies. children's responses to questions about how their bodies worked revealed some basic misunderstandings and errors. the significance of these data both for health education and for communicating with sick children ...19836640850
group l beta-haemolytic streptococcal infection in meat handlers: another streptococcal zoonosis?group l, beta-haemolytic streptococci can cause infection in dogs, pigs, cattle and sheep but there have been very few reports in man. in studies of skin infection in meat handlers we cultured group l streptococci from clinically infected wounds, impetigo and paronychia of 15 patients involved in the slaughter and processing of chickens and pigs. staphylococcus aureus was also present in eight (53%) of the lesions. at least five other infections with group l streptococci in meat and animal handl ...19873678390
angiostrongylus vasorum infection in dogs and slugs. 19827147643
toxocara species eggs in london parks. 19873604034
the dysgonic form of microsporum canis in n.w. london.an account is given of the occurrence in n.w. london of ringworm due to the dysgonic form of microsporum canis in cats, dogs, and humans. the unusual morphology of the dysgonic strain is described as is the extraordinary lability of the fungus in culture. the distribution of cases in man and animals in the area is mapped. the clinical and epidemiological behaviour of the fungus, as illustrated by four family outbreaks, differs little from that of the typical strain. the origin of the dysgonic st ...19807387885
prevalence of toxocara species eggs in the soil of five east london parks. 19873824844
studies on the epidemiology of uncinaria stenocephala infections in british greyhounds: development and persistence of larvae on herbage. 19817198820
storage mites culturing, sampling technique, identification and their role in housedust allergy in rural areas in the united kingdom.patients with symptoms suggesting housedust mite allergy were tested to storage mites, housedust, and dermatophagoides spp. housedust was examined for mites. all patients responded to storage mites. some were negative to dermatophagoides. all houses proved to have storage mites in the dust as well as dermatophagoides, mainly in food stores or pet beds. storage mites, therefore, are involved in dust allergy.19854014790
stephen hales' "statical way". 19853909194
crop-eared dobermanns. 19854090228
the epidemiology of hydatid disease in england and wales.the epidemiology of hydatid disease in man in england and wales, based on the data collected between 1981 and 1983 at the hydatid reference laboratory of the public health laboratory service, is presented. the incidence of hydatid disease was 42 cases per annum, with 2 cases per million population occurring in wales and 0.2 per million in england. the highest prevalence was in london amongst the immigrant population. the incidence in the indigenous population was 15.5 cases per annum, with 5.6 c ...19863950392
mad dogs and englishmen. the background to the new rabies act. 19744496202
letter: pet stealing. 19744450424
human rabies: wild animals challenge dogs as sources of contagion. 19705530591
a comparison of biotypes and serotypes of campylobacter sp. isolated from patients with enteritis and from animal and environmental sources.the origin of sporadic campylobacter infections has been investigated by means of a collaborative study. from a total of 1152 cases reported in north west england in 1982, campylobacter strains isolated during one month in each quarter of the year were biotyped and serotyped. for comparison, 875 strains of campylobacter isolated from environmental and animal sources were similarly examined. most strains from human beings were campylobacter jejuni; about half of them were of three serotypes. thos ...19846501895
parvovirus vaccination. 19854024444
prevalence of antibodies to neospora caninum in a population of urban dogs in england.of 163 dogs, randomly selected from those examined at the university of liverpool small animal hospital, 12.9 per cent had antibody titres > or = to 1/200 to neospora caninum in an indirect fluorescent antibody test. none was apparently suffering clinical neosporosis. there was no association between the occurrence of neospora antibodies and either toxoplasma antibodies measured by the dye test, sex, age, type of feeding or the presence of other dogs in the household. antibody was detected at ti ...19938447050
the seasonality of canine births and human campylobacteriosis: a hypothesis.the seasonality of canine births was investigated using records from the kennel club and the breeding centre for the guide dogs for the blind association. in these populations a distinct seasonal pattern was found with a greater number of puppies being born in the summer months than the winter. the hypothesis that the greater number of puppies acquired as pets during the summer months may contribute to the seasonal rise in human campylobacter cases, seen at this time, is discussed.19938472770
juvenile renal disease in a dobermann. 19846506437
canine and feline campylobacteriosis: epizootiology and clinical and public health features. 19836606637
vaccination clinics. 19863952979
studies on the epizootiology of canine coronavirus.the seroprevalence and, or, incidence of canine coronavirus infection was determined in several dog populations in the uk. seroprevalence ranged from 76 per cent for a rescue kennel to 100 per cent in a commercial breeding colony. in the rescue kennel there was no difference in seroprevalence of the virus between dogs less than or more than four months of age. in the breeding colony, subclinical seroconversion occurred between six and 10 weeks of age. the virus was isolated from faecal samples f ...19938382389
angiostrongylus vasorum infection in foxes (vulpes vulpes) in cornwall.a post mortem examination on a young fox which had been observed to be clinically ill revealed a severe infection with angiostrongylus vasorum. a further 11 foxes were examined and four were infected with the parasite; three of these also had advanced lesions of sarcoptic mange. the cases all occurred outside the previously defined focus of endemic infection for dogs in cornwall and they appear to be the first recorded cases of a vasorum in foxes in the united kingdom.19968931300
[the history of resuscitation]. 19664870036
pet health insurance. 19836609475
comparison of canine oropharyngeal malignancy in various geographical locations.the variation in prevalence of neoplasms over time and location has been of value in identifying environmental carcinogens. studies on the relative frequency of the different histological types of canine oropharyngeal malignant neoplasm have shown that squamous cell carcinoma of the tonsil occurs four times more commonly in south east england, and twice as frequently in the united states of america as in melbourne, australia. the prevalence of tonsillar squamous cell carcinoma in london in 1950 ...19846719788
prevalence of giardia in dogs and cats in the united kingdom: survey of an essex veterinary clinic. 19892617648
preliminary development of a live attenuated canine parvovirus vaccine from an isolate of british origin.canine parvovirus isolated from a case of haemorrhagic enteritis in a breeding kennel in england was passaged and cloned in cultured feline and canine cells. no significant evidence of pathogenicity was found during six serial passages of the modified virus back through young dogs. the attenuated virus was excreted by inoculated animals and spread rapidly to uninoculated animals held in contact. when high titre attenuated virus was given to the six-week-old offspring of a seropositive dam a prom ...19873035779
the changing incidence of human hydatid disease in england and wales.the incidence of hospital-diagnosed human hydatid disease acquired in the uk was estimated from a survey based on hospital activity analysis data for the period 1974-83. the average annual incidence in wales was 0.4 per 100,000 population compared with 0.02 per 100,000 in england. within wales, powys, and particularly brecknock, had the highest incidence (7 per 100,000 per year). compared with the period 1953-62, the average annual incidence for wales fell by half (from 0.8 to 0.4 per 100,000 pe ...19873428374
some haematological data for fallow deer (dama dama) in england.the concentrations of haemoglobin, erythrocytes and leucocytes and the packed cell volume, plasma viscosity and some red cell indices were measured in the blood of 42 fallow deer and analysed with respect to age, season and sex. the mean haemoglobin concentration was greater in females than in males. in all the deer the number of leucocytes was considerably smaller than in the usual domestic mammals, namely, cats, cattle, dogs, goats, horses, pigs and sheep. plasma viscosity was statistically gr ...19827146629
canine parvovirus infection. 19807210433
incidence of campylobacter, salmonella and shigella infections in dogs in an industrial town. 19807257102
shot dog. 19807361402
canine vaccination survey. 19807445324
canine parvovirus infection. 19807445338
species of flea found on cats and dogs in south west england: further evidence of their polyxenous state and implications for flea control.fleas were collected from 60 dogs and 32 cats living in south west england. ctenocephalides felis felis and ctenocephalides canis were found on both dogs and cats, with a marked preponderance of c felis felis on both species. more female fleas than males were found. there was no apparent tendency for c canis to be found more often in rural areas than in suburban areas. the survey confirmed the polyxenous nature of both species of flea. the significance of this state is discussed in relation to f ...19957610540
earliest attempt at free skin grafting. 19957639497
samuel jones gee (1839-1911) and stereotypic movements caused by apomorphia. 19957673956
hearing dogs. 19957709579
canine atopic disease: the prevalence of positive intradermal skin tests at two sites in the north and south of great britain.results of intradermal skin test responses to the same panel of 53 allergens were compared in 118 dogs with atopic disease presented at two geographical centres, edinburgh (87 cases) and london (31 cases). the allergens most commonly positive at both centres were human dander and dermatophagoides farinae, but positive tests to all of the allergens used occurred in at least one case. the mean number of allergens to which positive tests resulted in atopic dogs was 5.126 (edinburgh) and 5.129 (lond ...19957747407
the development of cimetidine: 1964-1976. a human story.there was still controversy regarding the physiology of acid secretion in 1964 when a team at smith kline & french laboratories in england started a project to prove the existence of more than one receptor for histamine and to find a substance capable of blocking the effects not blocked by the commonly used antihistamines. the team was convinced that histamine was the final mediator of acid secretion. after 8 years, james black and his coworkers published evidence of the first histamine2-recepto ...19947806839
contractility of lungs and air-tubes: experiments performed in 1840 by charles j.b. williams.in the 18th century, some medical practitioners considered the main pathological feature of asthma to be the production of mucus. later, during the 19th century, airway smooth muscle contraction was recognized to be a possible cause of airflow obstruction. however, not until 1840 was the contractility of airway smooth muscle clearly established by charles j.b. williams, a famous london physician. in a number of innovative experiments in dogs, rabbits, livestock and even donkeys, he showed: 1) th ...19948013615
strongyloides in british greyhounds. 19883363835
borrelia burgdorferi infection in uk horses.antibody levels (igg and igm) to borrelia burgdorferi were measured in the sera and synovial fluids of uk horses. western blotting against b. burgdorferi was also used on samples from seropositive horses. a low incidence of seropositivity was shown in horses from most parts of the uk. this increased in areas that have a high incidence of human and canine borreliosis (norfolk and south coast). leptospira infections of horses did not cause cross reactions in the b. burgdorferi elisa. most horses d ...19948542836
control of hydatid disease in wales.to evaluate the success of the south powys hydatid control programme by analysis of trends in cystic disease in humans and sheep and dog infestation.19968597734
charles drew and the origins of deep hypothermic circulatory arrest.convinced that the high risk of operation using the early heart-lung machines was due to a toxic effect of the oxygenators in use in the 1950s, charles drew of westminster hospital in london devised a circulatory support system in which the patient's own lungs functioned as the oxygenator. with this support, body temperature was reduced to the point where circulatory arrest could be tolerated for the time required to carry out the intracardiac operation. he used only this technique for the rest ...19979124943
cutaneous protothecosis in the dog: first confirmed case in britain. 19883201697
computer-aided veterinary learning at the university of cambridge.an approach of computer-assisted learning in veterinary education at the university of cambridge, involving the development of four types of learning module, is outlined. a tutorial on regional perineural anaesthesia in the horse, based on the familiar tape-slide format but with significant improvements, is described. a question and answer self-assessment package and a computer-based 'digital lecture' are also discussed, together with a case simulation involving the investigation of a polydipsic ...19968686151
rabies and quarantine. 19968938970
the distribution of clostridium difficile in the environment of south wales.a large study of the distribution of clostridium difficile in the environment of the cardiff area of south wales was performed with a methodology designed to maximise recovery. a total of 2580 samples was taken, with 184 (7.1%) yielding isolates. the highest yield for c. difficile was obtained from river waters, with 14 (87.5%) of 16 samples from four rivers positive, and from sea water samples with 7 (44%) of 15 positive from six beaches on the bristol channel. in addition, 7 (46.7%) of 15 samp ...19968683549
hearing dogs for the deaf. 19836889261
prevalence of toxocara ova in dog faeces. 19979061878
analysis of influenza a h3n2 strains isolated in england during 1995-1996 using polymerase chain reaction restriction.a polymerase chain reaction-restriction (pcr-restriction) endonuclease assay was developed to allow rapid analysis of influenza a h3n2 viruses circulating in england during 1995-1996. restriction endonuclease digestion with two enzymes of amplicons derived from pcr of the ha1 portion of the influenza haemagglutinin (ha) gene was able to differentiate antigenically similar influenza strains into two groups. group i variants were similar genetically to the 1995/96 vaccine strain, a/johannesburg/33 ...19979139090
epidemiological and diagnostic features of canine and feline dermatophytosis in the united kingdom from 1956 to 1991.between 1956 and 1991, 8349 samples from dogs and cats were received for investigation of suspected dermatophytosis, and 1368 (16 per cent) yielded positive cultures. cats had a significantly higher proportion of positive cultures (26 per cent) than dogs (10 per cent), and of these microsporum canis accounted for 92 per cent in cats and 65 per cent in dogs. the other isolates were diverse but mainly sylvatic dermatophytes, and m gypseum was isolated on only four occasions. different breeds of do ...19938212483
unseasonal snake bites in dogs. 200010839242
intrac vaccine: batch recall. 19979265715
hunting inquiry. 200011014492
skin prick testing in general practice: a pilot study.allergy skin prick testing is regarded as a routine diagnostic procedure in hospital settings, but its role in general practice is not yet defined. our aim was to explore the ways in which skin prick testing might facilitate the work of general practice nurses engaged in asthma patient care. a structured questionnaire was completed by 18 practice nurses before and again after administering allergy skin tests to four common aeroallergens (dust mite, grass pollen, cat and dog danders) to 319 conse ...19979378875
distribution of borrelia burgdorferi s.l. spirochaete dna in british ticks (argasidae and ixodidae) since the 19th century, assessed by pcr.the distribution of borrelia burgdorferi sensu lato, the lyme borreliosis agent, was surveyed in british ticks in the collection of the natural history museum, london. alcohol-preserved specimens of eight species of ticks known to attack humans were studied: ixodes ricinus, i. hexagonus, i. uriae, i. trianguliceps, dermacentor reticulatus, haemaphysalis punctata, rhipicephalus sanguineus and argas vespertilionis. the sample comprised all life stages and originated from a wide range of host speci ...19989513944
rabies and quarantine. 19979342091
unusual cryptosporidium species recovered from human faeces: first description of cryptosporidium felis and cryptosporidium 'dog type' from patients in england.dna was extracted from faecal samples collected from 1680 patients in which cryptosporidium oocysts were recognised by light microscopy. dna from faeces from five of these patients failed to amplify by pcr three gene fragments--the cryptosporidium oocyst wall protein (cowp) gene, the thrombospondin-related adhesive protein of cryptosporidium-1 (trap-c1) gene and the thrombospondin-related adhesive protein of cryptosporidium-2 (trap-c2) gene--with primers designed from c. parvum sequences. howeve ...200111232777
non-market costs of rabies policy. 19979342088
series of pancreatitis cases. 19989577765
residual visual functions of guide dog owners in the uk.numbers of guide dog owners (gdos) in the united kingdom reached 4700 by the end of 1998. despite this growing trend, little is known about the nature of their visual loss. this paper reports the results of a national three-centre investigation into the residual visual functions and ophthalmic conditions of guide dog owners. random samples of gdos (scotland n = 82, england n = 77, and northern ireland n = 87) underwent a detailed visual analysis and interview. gdos had an overall median age of 5 ...200111430622
use of sentinel lambs to survey the effect of an education programme on control of transmission of echinococcus granulosus in south powys, wales.in this article the effects of an education programme (area ii) on transmission of echinococcus granulosus from dogs to sheep in wales and of substitution of the education programme by a 6-weekly anthelmintic control programme (area i) are compared with the situation in an area where no control interventions had occurred (area iii). the education programme failed to prevent transmission of e. granulosus to sentinel lambs examined at 15 months of age, 6%, 4%, and 10% of which were infected in are ...19989868837
grease, anthraxgate, and kennel cough: a revisionist history of early veterinary vaccines.in conclusion, it is remarkable just how farsighted many of the early vaccine investigators were. jenner was apparently very comfortable with contagion and even recognized that infectious agents could gradually change and adapt to a new species. pasteur, long before his fowl cholera experiment, dreamed that attenuation could yield safe vaccines and it took him no time at all therefore to recognize the significance of that serendipitous experiment. the fact that two other investigators were also ...19999890006
[ancient theories on the genesis of allergic rhinopathy. from the beginnings to the 18th century]. 19979658632
facilities management. dog bytes dog. 199310124163
orf (contagious pustular dermatitis) in farmworkers: prevalence and risk factors in three areas of england.orf is a zoonotic skin disease which is commonly self-diagnosed by those who tend sheep and goats. this paper reports the prevalence, incidence and risk factors associated with the infection in a cohort of farmworkers from three areas of england, derived from the results of self-reporting and serology. twenty-three per cent of those employed or living on a sheep farm reported ever having had orf, and the antibody serological profiles indicated a prevalence of 4 per cent and an annual incidence o ...199910452390
reasons for the euthanasia of dogs and cats. 19989725180
longevity of british breeds of dog and its relationships with sex, size, cardiovascular variables and disease.the results of a questionnaire provided data about owners' perceptions of the cause of death of over 3000 british dogs. the mean age at death (all breeds, all causes) was 11 years one month, but in dogs dying of natural causes it was 12 years eight months. only 8 per cent of dogs lived beyond 15, and 64 per cent of dogs died of disease or were euthanased as a result of disease. nearly 16 per cent of deaths were attributed to cancer, twice as many as to heart disease. neutered females lived longe ...199910619607
a serological study of canine herpes virus-1 infection in the english dog population.an epidemiological survey investigated the prevalence of canine herpes virus-1 antibodies in a population of 325 pet dogs in england. sera were analysed for the presence of canine herpes virus-1 neutralising antibody by means of a serum neutralisation test and for virus-specific igg and igm by means of enzyme-linked immunosorbent assays. in contrast with published results from other parts of the world, canine herpes virus-1 infection was shown to be common among the domestic dog population of en ...19989739327
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