Publications

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the prevalence of intestinal nematodes in cats and dogs from lancashire, north-west england.to estimate prevalence of clinically-relevant intestinal nematodes in uk cats and dogs using the sensitive faecal analysis technique flotac.201627071856
epidemiology of cranial cruciate ligament disease diagnosis in dogs attending primary-care veterinary practices in england.to estimate the prevalence and risk factors for a diagnosis of cranial cruciate ligament (ccl) disease in dogs and to describe the management of such cases attending primary-care veterinary practices.201526118493
an epidemiological study of diabetes mellitus in dogs attending first opinion practice in the uk.this study aimed to estimate the prevalence of canine diabetes mellitus (dm) in primary-care clinics in england, to identify risk factors associated with dm and to describe the survival of affected dogs. cases of dm were identified within the electronic patient records of 89 small-animal practices. a nested case-control study identified risk factors for the diagnosis of dm using logistic regression models. cox proportional hazards models were used to analyse variables associated with survival. f ...201424570406
qualitative study of factors associated with antimicrobial usage in seven small animal veterinary practices in the uk.responsible use of antimicrobials by veterinarians is essential to contain antimicrobial resistance in pathogens relevant to public health. inappropriate antimicrobial use has been previously described in practice. however, there is scarce information on factors influencing antimicrobial usage in dogs and cats. we investigated intrinsic and extrinsic factors influencing decision-making of antimicrobial usage in first opinion small animal practices in the uk through the application of qualitative ...201425091861
pet ownership, dog types and attachment to pets in 9-10 year old children in liverpool, uk.little is known about ethnic, cultural and socioeconomic differences in childhood ownership and attitudes to pets. the objective of this study was to describe the factors associated with living with different pet types, as well as factors that may influence the intensity of relationship or 'attachment' that children have to their pet. data were collected using a survey of 1021 9-10 year old primary school children in a deprived area of the city of liverpool, uk.201323668544
a retrospective study of pyometra at five rspca hospitals in the uk: 1728 cases from 2006 to 2011.a retrospective cross-sectional study was used to analyse pyometra cases at five rspca animal hospitals across the uk from 2006 to 2011. a total of 1728 cases of pyometra were recovered from a female dog outpatient caseload of 78,469 animals, giving a total prevalence of 2.2 per cent over the study period. there was an annual increase in the incidence of pyometra within the population, while elective ovariohysterectomy caseload has declined. there were variations in breed and age at presentation ...201324114733
longevity and mortality of owned dogs in england.improved understanding of longevity represents a significant welfare opportunity for the domestic dog, given its unparalleled morphological diversity. epidemiological research using electronic patient records (eprs) collected from primary veterinary practices overcomes many inherent limitations of referral clinic, owner questionnaire and pet insurance data. clinical health data from 102,609 owned dogs attending first opinion veterinary practices (n=86) in central and southeast england were analy ...201324206631
the use of electronic collars for training domestic dogs: estimated prevalence, reasons and risk factors for use, and owner perceived success as compared to other training methods.the use of electronic training devices for dog training is controversial. the aims of this study were to give an indication of the extent to which dog owners use these devices in england, identify factors associated with their use, and compare owner report of outcomes. a convenience sample of dog owners in england was used to identify numbers using electronic training devices and identify reasons for use. factors associated with use of remote e-collars only were determined by comparing dogs trai ...201222748195
antibacterial prescribing patterns in small animal veterinary practice identified via savsnet: the small animal veterinary surveillance network.in this study, data from veterinary clinical records were collected via the small animal veterinary surveillance network (savsnet). over a three-month period, data were obtained from 22,859 consultations at 16 small animal practices in england and wales: 69 per cent from dogs, 24 per cent from cats, 3 per cent from rabbits and 4 per cent from miscellaneous species. the proportion of consults where prescribing of antibacterials was identified was 35.1 per cent for dogs, 48.5 per cent for cats and ...201121911433
disciplinary case dismissed. 201122141120
rabies postexposure prophylaxis in a uk travel clinic: ten years' experience.in 2009, 58.6 million uk residents traveled abroad. of these, 49.5 million (84.5%) visits were to europe and north america and 9.1 million (15.5%) were to other parts of the world. rabies is widely distributed and continues to be a major public health issue in many developing countries. the uk is free of rabies in carnivore host species, although cases of rabies in bats have been reported. this study examined the rabies postexposure prophylaxis (pep) service from 2000 to july 2009 at the liverpo ...201121722237
long-term follow-up after weight management in obese dogs: the role of diet in preventing regain.regain after weight loss is widely reported in humans, but there is little information on this phenomenon in dogs. the current study aim was to determine long-term success of a weight loss regime and those factors linked with regain. thirty-three obese dogs, that had successfully lost weight, were included, all enrolled between december 2004 and may 2009. after weight loss, dogs were switched to a maintenance regime and follow-up weight checks were performed periodically. a review of cases that ...201121570327
prevalence, distribution and risk associated with tick infestation of dogs in great britain.current concerns over the potential impacts of climate change and the increased movement between countries of people and companion animals on the distribution of ectoparasites, highlight the need for accurate understanding of existing prevalence patterns. without these future changes will not be detected. here, the distribution and prevalence of tick infestations of domestic dogs in great britain were examined. a total of 173 veterinary practices were recruited to monitor tick attachment to dogs ...201121418263
canine visit! in icu? 201121320107
Canine adder bites in the UK: a retrospective study of cases reported to the Veterinary Poisons Information Service.This retrospective study examined cases with follow-up reported to the Veterinary Poisons Information Service (VPIS) between September 1985 and December 2010. Most bites (69.2 per cent) occurred between April and July, particularly between 15:00 and 16:00 hours. Adder bites were more frequently reported in the south-east of England, particularly in Surrey. Swelling to the face and limbs was common, as was lethargy, depression, hyperthermia and tachycardia. About two-thirds of dogs developed both ...201121868437
oestrus ovis infestation of a dog in the uk.in march 2011, a dog on a sheep farm in the cotswolds, uk, expelled a mature live third-stage larva of the sheep nasal botfly, oestrus ovis, after a violent and traumatic sneezing episode. the dog had been infected with first-stage larvae deposited by an adult fly the previous autumn; larval development had progressed throughout the winter and spring with few apparent clinical signs and possibly masked by ongoing immunotherapy for an unrelated condition. identification of the parasite at the liv ...201122122385
investigation of farms linked to human patients with cryptosporidiosis in england and wales.the study investigates farms suspected of being sources of zoonotic human cryptosporidiosis. a variety of implicated farm animal species were sampled and tested to detect cryptosporidium oocysts and investigate genetic linkage with human patients. risk factor information was collected from each farm and analysed by multivariable logistic regression to detect significant associations between factors and cryptosporidium in animals. the results showed that average sample prevalence of cryptosporidi ...201020096944
infectious canine hepatitis in red foxes (vulpes vulpes) in the united kingdom.the pathological findings are described in three cases of infectious canine hepatitis in free-ranging red foxes (vulpes vulpes) in england. the foxes died after short periods of clinical illness. mild jaundice and hepatic congestion were evident grossly. on histopathological examination, intranuclear inclusion bodies were visible in hepatocytes, in association with hepatocyte dissociation and necrosis, as well as in renal glomeruli, renal tubular epithelial cells and vascular endothelial cells. ...201020097890
william hogarth's the painter and his pug: defining the "line of beauty". 201020231597
factors associated with cat ownership in a community in the uk.a census-based epidemiological study was carried out to investigate factors associated with cat ownership in a semi-rural community of 1278 households in cheshire, uk. twenty-two per cent of the households were identified as cat-owning and 52 per cent owned a pet of any type. there was evidence to suggest that some types of household were more likely to own a cat than others. multivariable logistic regression indicated that households were less likely to own a cat if they had one dog compared wi ...201020305290
risk factors for tail injuries in dogs in great britain.the aim of the current study was to quantify the risk of tail injury, to evaluate the extent to which tail docking reduces this risk, and to identify other major risk factors for tail injury in dogs in great britain. a nested case-control study was conducted during 2008 and 2009. data were obtained from a stratified random sample of veterinary practices throughout great britain, and questionnaires were sent to owners of dogs with tail injuries and owners of a randomly selected sample of dogs wit ...201020581358
prevalence, molecular typing and risk factor analysis for giardia duodenalis infections in dogs in a central london rescue shelter.a cross-sectional survey to investigate canine infections with giardia duodenalis was undertaken at a central london rescue shelter between october 2006 and march 2007. the objectives of the study were to (i) estimate the prevalence of infection in dogs admitted to a london dog shelter using a commercially available elisa-based test kit; (ii) identify the relative importance of potential dog level risk factors for infection; and (iii) identify the occurrence of different g. duodenalis assemblage ...201020609523
family dog ownership and levels of physical activity in childhood: findings from the child heart and health study in england.dog ownership is associated with higher physical activity levels in adults; whether this association occurs in children is unknown. we used accelerometry to examine physical activity levels in 2065 children aged 9 to 10 years. children from dog-owning families spent more time in light or moderate to vigorous physical activity and recorded higher levels of activity counts per minute (25; 95% confidence interval [ci]=6, 44) and steps per day (357; 95% ci=14, 701) than did children without dogs.201020634441
coonhound paralysis in south yorkshire? 201020802195
computed tomography variations in morphology of the canine atlas in dogs with and without atlantoaxial subluxation.computed tomography images of 120 dogs were reviewed to characterize variations in atlas morphology, and to identify breed-specific morphologic features. the neural arch of the atlas was thicker in large dogs and male dogs than in small dogs, having a layer of trabecular bone between the inner and outer layers of compact bone. the transverse processes of the atlas were relatively longer in large dogs than in small dogs. twelve (10%) dogs had incomplete ossification of the atlas. incomplete ossif ...201021158229
the relationship between substance use and exit security on psychiatric wards.in this paper we report on the rates of drug/alcohol use on acute psychiatric wards in relation to levels and intensity of exit security measures.201021073504
characterization of pneumonia due to streptococcus equi subsp. zooepidemicus in dogs.streptococcus equi subsp. zooepidemicus has been linked to cases of acute fatal pneumonia in dogs in several countries. outbreaks can occur in kenneled dog populations and result in significant levels of morbidity and mortality. this highly contagious disease is characterized by the sudden onset of clinical signs, including pyrexia, dyspnea, and hemorrhagic nasal discharge. the pathogenesis of s. equi subsp. zooepidemicus infection in dogs is poorly understood. this study systematically characte ...201020861329
exonic mutations in the l2hgdh gene in staffordshire bull terriers. 201020852250
canine dilated cardiomyopathy: a retrospective study of signalment, presentation and clinical findings in 369 cases.to review the clinical and diagnostic findings and survival of dilated cardiomyopathy from a large population of dogs in england.200919037887
sequence analysis of divergent canine coronavirus strains present in a uk dog population.forty faecal samples were tested by rt-pcr using coronavirus consensus primers to determine faecal shedding of canine coronavirus (ccov) and canine respiratory coronavirus (crcov) in a dog population housed at a rescue centre. seven samples were positive for ccov while all samples were negative for crcov. sequence analysis of five ccov strains showed a high similarity with transmissible gastroenteritis virus (tgev) at the n-terminus of the spike protein. all strains contained an open reading fra ...200919162099
emerging canine angiostrongylosis in northern england: five fatal cases. 200919188347
elevated canine pancreatic lipase immunoreactivity concentration in dogs with inflammatory bowel disease is associated with a negative outcome.to investigate whether elevated canine pancreatic lipase immunoreactivity (cpli) concentrations in dogs with inflammatory bowel disease (ibd) is associated with a worse clinical outcome.200919261082
rickets in lion cubs at the london zoo in 1889: some new insights.in 1889, when dr john bland-sutton, a prominent surgeon in london, england, was consulted concerning fatal rickets in more than 20 successive litters of lion cubs at the london zoo, he evaluated the role of diet relative to the development of rickets. he prescribed goat meat and bones and cod-liver oil to be added to the lean horse-meat diet of the cubs and their mothers. rickets reversed, the cubs survived, and litters were reared successfully. in classic controlled studies conducted in puppies ...200919349374
canine leishmaniosis in the united kingdom: a zoonotic disease waiting for a vector?leishmaniosis is an important sand fly transmitted protozoan disease of dogs and humans. in northern europe, infection is mainly restricted to dogs that have travelled to and/or from endemic areas of the mediterranean region during periods when there is high sand fly exposure, mostly between march and november. infected dogs in these areas in northern latitudes are a potential reservoir should incursion of a competent vector occur. however, information on the scale of the potential reservoir in ...200919369005
canine angiostrongylosis in northern england. 200919395725
drug-resistant salmonella typhimurium dt 120: use of pfge and mlva in a putative international outbreak investigation.isolates of salmonella enterica serovar typhimurium belonging to definitive phage type (dt) 120 (salmonella typhimurium dt 120) from simultaneous outbreaks of infection in the england and denmark have been compared on the basis of antibiogram, pulsed-field gel electrophoresis (pfge), and multiple locus variable number tandem repeat analysis (mlva). isolates from england had the resistance profile (ampicillin, streptomycin, sulfamethoxazole, and tetracycline), mlva profiles 2-4-4-0-2, 2-4-5-0-2, ...200919432517
brief report: don't kiss a sleeping dog: the first assessment of "the blue dog" bite prevention program.the authors attempted to remedy the current lack of empirically evaluated dog-bite prevention programs for children under 7 by assessing children's learning success with the "blue dog" cd.200919578138
canine intrapericardial cyst - complicated surgical correction of an unusual cause of right heart failure.intrapericardial cysts are non-neoplastic structures that can become clinically significant by compressing cardiac chambers. surgical excision is recommended to resolve clinical signs and this has been reported to be easily achieved by blunt manipulation. the present report describes a case of an intrapericardial cyst in a dog. the singularity of this case lays on the fact that the patient was presented unusually late, at the age of four years, and most importantly that its surgical correction w ...200919769671
chicken consumption and use of acid-suppressing medications as risk factors for campylobacter enteritis, england.in a case-control study of campylobacter spp. risk factors in england during 2005-2006, we identified recent consumption of commercially prepared chicken as an important risk factor. the risk for illness associated with recent chicken consumption was much lower for persons who regularly ate chicken than in those who did not, which suggests that partial immunologic protection may follow regular chicken preparation or consumption. chicken-related risk factors accounted for 41% of cases; acid-suppr ...200919788807
risk factors for the carriage of campylobacter upsaliensis by dogs in a community in cheshire.samples of faeces were taken from 183 healthy pet dogs in a census-based, cross-sectional study in cheshire; culture methods were used to detect any campylobacter species and a direct pcr was used to detect campylobacter upsaliensis. forty-six of the dogs were positive for c upsaliensis by either culture or direct pcr, giving a prevalence of 25.1 per cent (95 per cent confidence interval [ci] 19.0 to 32.1 per cent). one sample was positive by culture for campylobacter jejuni (95 per cent ci 0.0 ...200919880860
dog fight: darwin as animal advocate in the antivivisection controversy of 1875.the traditional characterization of charles darwin as a strong advocate of physiological experimentation on animals was posited in richard french's antivivisection and medical science in victorian england (1975), where french portrayed him as a soldier in thomas huxley's efforts to preserve anatomical experimentation on animals unfettered by government regulation. that interpretation relied too much on, inter alia, huxley's own description of the legislative battles of 1875, and shared many hist ...200919917485
wren, boyle, and the origins of intravenous injections and the royal society of london. 200920029260
il13 gene polymorphisms modify the effect of exposure to tobacco smoke on persistent wheeze and asthma in childhood, a longitudinal study.tobacco smoke and genetic susceptibility are risk factors for asthma and wheezing. the aim of this study was to investigate whether there is a combined effect of interleukin-13 gene (il13) polymorphisms and tobacco smoke on persistent childhood wheezing and asthma.200818186920
retrospective review of 50 canine nasal tumours evaluated by low-field magnetic resonance imaging.low-field magnetic resonance imaging machines are being used more often in veterinary practice for the investigation of sinonasal disease. the aim of this retrospective study was to describe and characterise the low-field magnetic resonance imaging features of nasal tumours in dogs.200818373540
dog-human and dog-dog interactions of 260 dog-owning households in a community in cheshire.this study investigated the nature and frequency of the contacts that occur between dogs, and between dogs and people, by means of a questionnaire survey of 260 dog-owning households in a community in cheshire, uk. the contacts were highly variable and were affected by the size, sex and age of the dog, individual dog behaviours, human behaviours and human preferences in the management of the dog. a number of situations were identified that may be important in relation to zoonoses, including slee ...200818390853
angiostrongylus vasorum and eucoleus aerophilus in foxes (vulpes vulpes) in great britain.the nematode parasite angiostrongylus vasorum is a source of increasing concern in several parts of the world, where it causes significant disease in dogs. wild canids, especially foxes, are likely to have a role in the epidemiology of canine infection, and the parasite could also affect fox health and population dynamics. the heart and pulmonary vasculature of 546 foxes culled mostly by gamekeepers in great britain in 2005-2006 were examined by dissection and a modified flushing technique. fort ...200818407416
rabies virus in a dog imported to the uk from sri lanka. 200818453383
disease importation and animal welfare. 200818622001
comparison of sevoflurane and isoflurane in dogs anaesthetised for clinical surgical or diagnostic procedures.to assess attributes of sevoflurane for routine clinical anaesthesia in dogs by comparison with the established volatile anaesthetic isoflurane.200818631219
canine dynamic left ventricular outflow tract obstruction: assessment of myocardial function and clinical outcome.the aims of this study were (i) to evaluate echocardiographic findings and myocardial function including pulsed wave tissue doppler imaging in dogs with naturally occurring dynamic left ventricular outflow tract obstruction and (ii) to investigate the clinical outcome and response to therapy in these dogs.200818684141
computed tomography as an aid to management of chronic oropharyngeal stick injury in the dog.to describe the use of computed tomography scanning in the management of dogs with chronic signs after oropharyngeal stick injury.200818684147
metaldehyde poisoning of dogs. 200818791216
toxocara species egg contamination of soil from children's play areas in southern england. 200818820328
how often do veterinarians assess the bodyweight and body condition of dogs?measurements of bodyweight and body condition are useful for monitoring the state of health of companion animals, but the frequency with which they are used by veterinarians in general practice is not known. information derived from 148 dogs was analysed to determine how often their bodyweight and body condition had been assessed. bodyweight had been measured at least once in 103 (70 per cent) of the dogs. the median time between the measurements was 114 days (range five days to 6.8 years), and ...200818953073
implantable loop recorders: a viable diagnostic tool in veterinary medicine.the purpose of this study was to investigate whether implantable loop recorders could be used in the diagnosis of unexplained collapse in dogs.200819006489
['pet obesity epidemic]. 200819058745
metaldehyde poisoning of dogs. 200818776181
prevalence of zoonotic nematode species in dogs in lancashire. 200718065815
indications, outcomes and complications following lateral thoracotomy in dogs and cats.lateral thoracotomy is widely used for surgical management of thoracic diseases in small animals. the purpose of this paper is to describe the indications for lateral thoracotomy in dogs and cats and the associated outcomes and complications.200718045379
clinical effects and outcome of feline permethrin spot-on poisonings reported to the veterinary poisons information service (vpis), london.permethrin is a pyrethroid insecticide used in dermally applied spot-on flea treatments for dogs. permethrin-based spot-on preparations are contraindicated in cats because of the high risk of toxicosis. the veterinary poisons information service (vpis) is a 24-h access telephone service that provides veterinary professionals in the united kingdom with information on the management of poisoned animals. in a review of 286 cases reported to the vpis regarding inappropriate feline exposure to permet ...200717627861
retrospective evaluation of the long-term outcome of non-surgical management of 74 dogs with clinical hip dysplasia.the long-term outcome for dogs treated non-surgically for clinical signs of canine hip dysplasia were evaluated retrospectively; 74 dogs were evaluated by a postal questionnaire sent to their owners, and 24 of these were also evaluated by a veterinary clinical examination. a total of 11 outcome variables were evaluated. depending on the variable assessed, between 31 (41.9 per cent) and 49 (66.2 per cent) of the dogs remained clinically affected according to their owner's assessment, and between ...200717435096
five cases of canine dysautonomia in england (2004 to 2006).canine dysautonomia was diagnosed definitively in five dogs by histopathology. all dogs were seen between june 2004 and july 2006 and originated from south-east england; four dogs originated from an urban area and one from a rural area. of the urban dogs, one had recently visited scotland and one had visited a kennel in a rural area nearby. acute-onset but progressive vomiting, diarrhoea, depression and inappetence were the most common presenting clinical signs. reduced or absent anal tone, dysu ...200717425697
a prospective study to determine the incidence of atopy in children undergoing adenotonsillectomy for obstructive sleep apnea.to investigate the relationship between adenotonsillar hypertrophy seen in pediatric obstructive sleep apnea and upper airway allergy to airborne allergens.200716979762
issues of human rabies immunoglobulin and vaccine: policy versus practice.a retrospective audit was conducted of all issues of rabies vaccine or human rabies immunoglobulin (hrig) from the clinical microbiology department at university hospital aintree for post-exposure prophylaxis. the appropriateness of management was reviewed by a blinded panel, which used guidelines issued by the health protection agency (hpa) as a standard. thirty-six enquiries, on average 9 days following exposure, led to issues of hrig, rabies vaccine or both. dog bites accounted for the majori ...200717148554
vet to be suspended for 'cosmetic' tail docking. 200717209095
docking of dogs' tails. 200717237462
docking of dogs' tails. 200717237464
concurrent tail docking and microchipping in puppies. 200717351183
improved survival in a retrospective cohort of 28 dogs with insulinoma.to determine the survival times for a cohort of dogs with insulinoma and to describe the impact of medical therapy both in non-surgical cases and in surgical cases following relapse.200717355606
analysis of the dermatophyte species isolated in the british isles between 1980 and 2005 and review of worldwide dermatophyte trends over the last three decades.infections of the skin, hair and nails by dermatophyte fungi are common in developed and developing countries alike. however, the species involved and the resulting clinical entities vary both geographically and with time. we have surveyed 15,333 dermatophytes obtained from primary isolations at the mycology reference laboratory, bristol, uk from 1980 through 2005. several striking trends in dermatophyte prevalence were apparent over this period. the relative frequencies of isolations of microsp ...200717365649
factors associated with dog ownership and contact with dogs in a uk community.dogs are popular pets in many countries. identifying differences between those who own dogs or have contact with dogs, and those who do not, is useful to those interested in the human-animal bond, human health and for provision of veterinary services. this census-based, epidemiological study aimed to investigate factors associated with dog ownership and contact with dogs, in a semi-rural community of 1278 households in cheshire, uk.200717407583
analysis of climatic predictions for extrinsic incubation of dirofilaria in the united kingdom.transmission of dirofilariasis in europe is dependent upon the presence of sufficient numbers of infected dogs, susceptible mosquitoes, and a suitable climate to permit extrinsic incubation of dirofilaria in the mosquito intermediate host. dogs returning to the united kingdom from overseas have been infected with several vector-borne infections (babesia, ehrlichia, leishmania, and dirofilaria), and this paper assesses the climatic constraints on the potential rate of extrinsic incubation of diro ...200717417953
out-of-hours emergency cover. 200717496279
rabies vaccination. 200717545652
staphylococcus schleiferi subspecies coagulans in companion animals. 200717652440
juvenile nephropathy in 37 boxer dogs.the purpose of this study was to review and characterise the clinical presentation of young boxer dogs with chronic kidney disease referred to the authors' institutions.200717727634
patellar luxation as a complication of surgical intervention for the management of cranial cruciate ligament rupture in dogs. a retrospective study of 32 cases.this retrospective study identified 32 cases of patellar luxation which occurred as a complication of surgical intervention for cranial cruciate ligament rupture (cclr). the complication was recorded mostly in larger (>/=20 kg) dogs with the labrador retriever being the most common breed. the complication followed extra-capsular, intra-capsular and tibial plateau levelling surgery. the mean time from cclr surgery to the diagnosis of patellar luxation was 14 weeks. the incidence of patellar luxat ...200717846687
on the origins of the conceptual system.contrary to the conventional view of infancy as a sensorimotor period without conceptual thought, research over the past 20 years has shown that preverbal infants are capable of at least 3 conceptual functions: forming concepts with which to interpret the world, recall of the past, and engaging in conceptual generalization. research is described indicating that the 1st concepts tend to be global in scope, such as animal or container, and that the course of conceptual development in the first 2 y ...200718020739
extended-spectrum beta-lactamase-producing bacteria isolated from companion animals. 200718024930
experimental confirmation by sir victor horsley of the relationship between thyroid gland dysfunction and myxedema.whereas sir victor horsley is well known for his many contributions to neurosurgery, this is not the case for his treatments for both myxedema and cretinism. horsley's research on thyroid physiology was concentrated in the years 1884-1890, while he was director of the brown institute for animals. based upon experimentation with dogs and monkeys as well as some human patients, horsley demonstrated conclusively that removal of the thyroid gland produced tremors, rigidity, and paralysis, which he a ...200616910875
outcomes of intrahepatic portosystemic shunts occluded with ameroid constrictors in nine dogs and one cat.to report outcome after ameroid constrictor (ac) use for single intrahepatic portosystemic shunts (ipss).200616635012
immunoglobulin deficiency in cavalier king charles spaniels with pneumocystis pneumonia.serum concentrations of immunoglobulin g (igg), igm, and iga were measured in 9 cavalier king charles spaniels with pneumonia caused by pneumocystis sp that were examined at 4 veterinary surgeries in the united kingdom (uk) between september 2001 and november 2002. pneumocystis pneumonia was confirmed in all dogs by visualization of the organism in bronchoalveolar lavage fluid or a transthoracic lung aspirate. two dogs had a history of demodicosis. immunoglobulin concentrations also were measure ...200616734084
vascular endothelial growth factor expression in canine intracranial meningiomas and association with patient survival.vascular endothelial growth factor (vegf) is a regulator of angiogenesis and vascular permeability. in human patients with meningiomas, increased vegf expression is predictive of postsurgical recurrence. the objectives of this study were to evaluate vegf expression in canine intracranial meningiomas and to determine whether an association between vegf expression and patient survival existed.200616734105
is there a causal association between genotoxicity and the imposex effect?there is a growing body of evidence that indicates common environmental pollutants are capable of disrupting reproductive and developmental processes by interfering with the actions of endogenous hormones. many reports of endocrine disruption describe changes in the normal development of organs and tissues that are consistent with genetic damage, and recent studies confirm that many chemicals classified to have hormone-modulating effects also possess carcinogenic and mutagenic potential. to date ...200616818242
a retrospective analysis of case series using home-prepared and chicken hydrolysate diets in the diagnosis of adverse food reactions in 181 pruritic dogs.the purpose of this retrospective study was to compare home-prepared and chicken hydrolysate diets in the diagnosis of canine adverse food reactions (afr). seventy-two dogs were fed home-prepared diets and 109 were fed hydrolysate. owners chose the type of diet at presentation, and ingredients of home-prepared diets were selected depending on each dog's dietary history. ectoparasitic infestations and microbial infections were treated during the trials. cutaneous and gastrointestinal signs and pr ...200616827671
angiostrongylus vasorum in canids. 200616829606
animal welfare bill granted second reading. 200616415223
the relative risk of police use-of-force options: evaluating the potential for deployment of electronic weaponry.an electronic weapon, the taser m26, has recently entered the use-of-force continuum for police officers in england and wales and is currently licensed for use by authorised firearms officers only. the aim of this report was to assess the relative risk of injury to officers and subjects of police use-of-force options and to evaluate whether the current positioning of the m26 in the use-of-force hierarchy is appropriate. we analysed use-of-force data from northamptonshire police force and m26 fie ...200616442332
patterns and significance of bite wounds in eurasian otters (lutra lutra) in southern and south-west england.postmortem examinations were carried out on 379 otters found dead in southern and south-west england between 1988 and 2003. most (81 per cent) were road casualties, but many had open bite wounds and in some cases these had proved fatal. mortality was strongly seasonal and was positively correlated with night length. although numbers decreased in the summer months, the prevalence of bite wounds in adults was highest in late summer. the number of otters examined annually and the prevalence of bite ...200616443836
serological prevalence of canine respiratory coronavirus.canine respiratory coronavirus (crcov) has recently been detected in dogs; it is a group 2 coronavirus showing similarity to bovine coronavirus (bcov) but is distinct from canine enteric coronavirus (cecov). crcov may play an important role in canine infectious respiratory disease (cird) either by predisposing to further and potentially more serious viral and bacterial infections or possibly as a primary pathogen. the prevalence of serum antibodies to crcov, in a population of dogs in the south ...200616551493
mrsa in companion animals. 200617041070
association of spinal cord compression seen on magnetic resonance imaging with clinical outcome in 67 dogs with thoracolumbar intervertebral disc extrusion.to determine whether there is an association between the degree of transverse spinal cord compression detected by magnetic resonance imaging following thoracolumbar hansen type 1 intervertebral disc disease in dogs and their presenting and postsurgical neurological status.200617076787
cataract in the uk leonberger population.to survey the leonberger, a numerically small breed in the uk, for the presence of cataract and find statistical support for the possible presence of inherited forms of cataract.200616939464
use of the ao veterinary mini 't'-plate for stabilisation of distal radius and ulna fractures in toy breed dogs.the use of the ao (arbeitsgemeinschaft für osteosynthesefragen) veterinary mini 't'-plate for stabilisation of distal radius and ulna fractures in toy breed dogs was evaluated in a retrospective study. all of the 14 dogs in the study weighed 3.5 kg or less. the ao mini 't'-plate was used as the final means of fixation in all cases. it was used as the primary form of stabilisation in ten dogs, and in four dogs it was used at revision surgery. in all cases, of the fractures healed. return to funct ...200516594212
magnetic resonance imaging findings of presumed cerebellar cerebrovascular accident in twelve dogs.the magnetic resonance imaging (mri) findings of presumed cerebrovascular accident in 12 dogs are described. fourteen lesions were seen, commonly (11 of 14) within the gray matter of the cerebellar hemispheres or vermis. thirteen lesions were hyperintense on t2-weighted images (in 11 dogs) and one was hypointense. eleven of 14 lesions were within the region supplied by the rostral cerebellar artery or one of its main branches and there was no, or minimal, mass effect. contrast enhancement was on ...200515693551
magnetic resonance imaging findings in 25 dogs with inflammatory cerebrospinal fluid.to describe the signs that may be associated with intracranial inflammatory conditions, magnetic resonance (mr) images of 25 dogs that had inflammatory cerebrospinal fluid (csf) were mixed with those of a control group of 40 dogs that had csf negative for inflammatory disease and reviewed without knowledge of the clinical signs or diagnosis. csf was considered inflammatory if the protein level was > 0.25 g/l and the white cell count was > 5 mm(-3). abnormalities were found by mr imaging in 19 (7 ...200515693553
topical fusidic acid/betamethasone-containing gel compared to systemic therapy in the treatment of canine acute moist dermatitis.the efficacy of a topical preparation containing 0.5% fusidic acid and 0.1% betamethasone-17-valerate was compared to a systemic therapy (comprising a combination of parenteral dexamethasone and oral clavulanate-potentiated amoxycillin) in the treatment of 104 dogs with acute moist dermatitis. significant improvement was evident after seven days in both treatment groups in all clinical parameters assessed and there was no significant difference in the overall response between the two treatment g ...200515727921
west midlands vet to be struck off. 200515747653
long-term survival of 23 dogs with pericardial effusions.twenty-three dogs with pericardial effusions were identified from case records made between 1992 and 2000. fourteen of the 23 were diagnosed with idiopathic pericardial effusions, and three of these were treated successfully by one pericardiocentesis. in the remaining 11 cases the pericardial effusion recurred; six cases were managed long-term by either two (three cases), three (two cases), or 11 repeated pericardiocenteses, and the remaining five were treated by pericardiectomy. the median surv ...200515866900
change to greyhound rules of racing. 200515866910
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