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[presence of htlv-i antibodies in patients with sexually transmitted diseases].the prevalence of human t-lymphotropic type i virus (htlv-i) among patients with sexually-transmitted diseases is studied in russia. primary screening of antibodies to htlv-i in the sera was carried out by enzyme immunoassay with recombinant gag and env htlv-i-specific antigens synthesized in escherichia coli. for secondary screening, serodia htlv-i and vironostika microelisa system kits were used. none of the 1271 serum samples collected in the towns of perm and ekaterinburg was htlv-i-positive ...19989702811
[epidemiological and genetical characteristics of first forty cases of hiv infection in perm region].the paper sums up molecular epidemiological data on all variants of human immunodeficiency virus type 1 (hiv-1) isolated in the perm region in august 1988-march 1998. a total of 24 foci (40 cases) of hiv infection were detected; 20 of these were imported from other regions (russian federation, ukraine, belarus, bulgaria, poland, uzbekistan, yugoslavia). in august 1988-september 1996 viruses of 3 env subtypes (b, d, and g) were isolated in the region, and the virus was mainly sexually transmitted ...200010971960
[the monitoring of the spread of drug abuse as an element in the epidemiological surveillance of socially significant infections].the necessity of monitoring the spread of drug addiction in the system of epidemiological surveillance on hiv infection and parenteral virus hepatitides is shown. the results of the epidemiological diagnostics of registered drug addiction are presented. the criteria for the assessment of the epidemiological effectiveness of epidemiological surveillance on drug addiction are determined. as revealed in this study, during the period of 1991-1998 morbidity in drug addiction rose 57-fold in perm prov ...200010994098
[the hiv-infection outbreak in the town lys'va (perm region): homozygote genotype ccr5 delta32/ccr5 delta32 provides the high level of the persistence in the parenteral transmission of the virus].specific features of human immunodeficiency virus type 1 (hiv-1) transmission among injecting drug users were studied on hiv infection outbreak in lysva, the perm region. during the period from november 1998 to march 2000, 32 injecting drug users infected with the subtype a hiv-1 variant originating from the same source, were found in this town. to understand the role of the ccr5 delta 32 mutation in parenteral transmission of hiv-1 the distribution of the mutant ccr5 delta 32 allele in hiv-infe ...200212271718
[biological properties of hiv-1 variants circulating among drug users in russia].human immunodeficiency virus type 1 variants belonging to subtype a, as well as recombinant gaga/engvb variants, derived from hiv-infected patients living in the moscow and perm regions, were isolated and characterized. intravenous administration of psychoactive drugs was a major risk factor of the infection for all the patients. all the examined isolates of hiv-1 types a and a/b were shown to be characterized by a low virus-specific activity and to be used as secondary ccr5 and cxcr4 protein re ...200516104518
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