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a unifying reference system for clinical enzymology: aspartate aminotransferase and the international clinical enzyme scale.a review of methodology for determining aspartate aminotransferase (asat; ec 2.6.1.1), including recent national and international recommendations, indicates that standardization of methodology alone will not bring interlaboratory compatibility of asat results. we propose that an additional component to standardization is needed, namely, enzyme reference materials. furthermore, we suggest that stable, well-defined asat materials from human sources are currently available. these primary reference ...19846329551
arthur purdy stout (1885-1967). the man and the surgical pathologist. 19846369999
marion b. sulzberger, m.d.--a human being. 19846384084
impact of influenza on a nursing home population--new york. 19836402656
the william allan memorial award. presented to elizabeth f. neufeld, ph. d., at the annual meeting of the american society of human genetics detroit, september 29-october 2, 1982.the opportunity for this presentation provides me with three gratifications. the first and most important is that the scientist being honored is elizabeth neufeld. the second is the honor bestowed upon me by being selected to introduce dr. neufeld. finally, the preparation of this introduction has provided me with the opportunity to reconstruct a scientific career from its beginnings to its present exciting momentum, an exercise in which i was helped with great enthusiasm by a number of people w ...19836417998
influenza outbreaks--district of columbia, iowa, louisiana, new york city, north carolina. 19846420666
orthotopic cardiac transplantation in a veterans administration hospital.of 57 patients referred to the mcguire veterans administration medical center, richmond, va, for evaluation for cardiac transplantation, 18 received allografts. the overall graft survival rate was 67% from two to 24 months after transplantation. in 15 recipients receiving immunosuppression with rabbit anti-human thymocyte globulin, prednisone, and azathioprine, previous transfusion and hla-dr matching resulted in improved graft survival. in three patients receiving cyclosporin and prednisone, hy ...19846422905
william saunders: the united states army's first dentist--west point's forgotten man. 19846433224
the use of epidemiology and clinical toxicology to assess environmental health problems.historically, epidemiology has played an important role in the changes that have taken place over time as epidemics of important infectious diseases have been replaced with modern epidemics of chronic, degenerative diseases such as elevated blood pressure, various types of cancers, diabetes, and stroke, among others. two illustrations of the early uses of epidemiologic methods in investigations of disease outbreaks are described in the work of john snow, who described outbreaks of cholera in the ...19846436910
unbalanced robertsonian translocations associated with down's syndrome or patau's syndrome: chromosome subtype, proportion inherited, mutation rates, and sex ratio.summary data are presented on 168 d/21 and 131 g/21 translocation trisomies reported to the new york state chromosome registry. by combining these data with others from the literature it is estimated that about 59% of d/21 cases are the result of mutation in hte parental generation; the rest are translocations inherited from parental carriers (39% maternal, 3% paternal). the proportion of mutants is about 10% greater for 14/21 cases and significant lower for 13/21 cases. of g/21 cases 93% are mu ...19816459988
analysis of paternity. the use of hla and red cell antigens.over a 6-year period, 866 cases were analyzed for disputed parentage. in 194 cases (22%), the alleged father was excluded as the biological father. one hundred and eight-one cases (93%) were direct exclusions, and 13 cases (7%) were indirect exclusions. ninety-two percent of falsely accused men were identified by typing for hla antigens alone. exclusions based solely on red cell data occurred in 8 percent of the cases. when only hla testing was performed, 177 of 362 (43%) cases had a probability ...19846464160
evaluation of a computerized drug review system: impact, attitudes, and interactions.a study was carried out across 11 psychiatric and mental retardation, and developmental disabilities facilities to investigate the impact of a computerized drug prescription monitoring system on clinicians' prescribing behavior, knowledge of pharmacotherapy, attitudes toward computers, and the relationships between their attitudes and changes in their prescribing practices. the results document that surveillance systems can improve prescribing practices. the tangible feedback provided by the exc ...19846488756
california serogroup viruses in new york state: the role of subtypes in human infections.the roles of various subtypes of the california serogroup viruses as infectious agents and as neuropathogens were evaluated by using the plaque reduction neutralization test. sera from 394 patients with central nervous system (cns) infections during 1971-1982 and from 501 persons without cns manifestations were studied. jamestown canyon (jc) and la crosse (lac) viruses were found to have been common infectious agents in new york state for at least 16 years. jc virus was the prevalent indicated a ...19846507732
the indochinese: strategies for health survival.compounding the "culture shock" of the indochinese refugees were added problems of unemployment, and lack of housing and educational facilities, all leading to emotional distress. traditional service delivery systems failed to show interest, much less offer needed service to the refugees who were stereotyped as deviant, unmotivated and resistant. the limited service that was offered ignored significant ethno-cultural factors central to effective intervention. an innovative approach was required. ...19846511218
legislation raising the legal drinking age in massachusetts from 18 to 20: effect on 16 and 17 year-olds.the 1979 massachusetts law raising the legal drinking age from 18 to 20 is examined--the effects on the drinking, drinking and driving, and nonfatal and fatal crash involvement of 16-17 yr-olds, teenagers immediately younger than those targeted by the law. data from massachusetts are compared with those from new york state, where the drinking age remained at 18. a total of 3 yr of survey data from the two states and 6 yr of data from the department of transportation's fatal accident reporting sy ...19846521479
morganella morganii: epidemiology of bacteremic disease.a retrospective review of microbiology records revealed 19 documented episodes of m. morganii bacteremia in 18 patients at a veterans administration hospital during a 5.5 year period. thirteen of 19 bacteremias were related to nosocomial infections; 11 of the 13 nosocomial bacteremias occurred in surgical patients. nine of the 13 patients with nosocomial bacteremia had received recent therapy with a beta-lactam antibiotic. the most common source of bacteremia was a postoperative wound infection ...19846561180
trihalomethanes in drinking water and human colorectal cancer.the relation of trihalomethanes (thm) to colorectal cancer was evaluated. a total of 395 colorectal cancer deaths among white women teachers in new york state was compared to an equal number of deaths of teachers from noncancerous causes. cumulative chloroform (chcl3) exposure was estimated by the application of a statistical model to operational records from the individual water treatment facilities that served the home and work addresses of each study subject during the 20 years prior to death ...19846583440
an outbreak of influenza a in a nursing home, 1982. 19846588319
particle-induced x-ray emission (pixe) analysis of trace elements in human coronal dentin.mass concentrations reported on the elemental composition of human dentin show great discrepancies between different investigations using various techniques. the purpose of the study was to determine the concentrations of bromine (br), copper (cu), iron (fe), strontium (sr) and zinc (zn) in the coronal dentin of permanent teeth from sweden and from new york city. particle-induced x-ray emission (pixe) was used for the analyses. there were no statistically significant differences in elemental com ...19846588603
recruitment and retention of disadvantaged students in baccalaureate nursing programs. 19846589375
mirex in human milk in upstate new york. 19836651347
group intervention: a psychosocial and educational approach to open heart surgery patients and their families.fear and apprehension usually accompany surgery on the human heart. experience and research have demonstrated that many patients who have undergone open heart surgery have less than optimal psychological outcomes. this article describes the response of one university hospital to the physiological and psychological needs of the cardiovascular surgery patient during the final phase of hospitalization. to give patients and families an opportunity to deal with their questions and concerns about disc ...19836670046
the distribution of chromosomal genotypes associated with turner's syndrome: livebirth prevalence rates and evidence for diminished fetal mortality and severity in genotypes associated with structural x abnormalities or mosaicism.the proportions of chromosomal genotypes associated with the turner syndrome genotype (excluding those with a y chromosome) in embryonic and fetal deaths, in fetuses diagnosed prenatally, and in living individuals were reviewed. the ratio of apparent non-mosaic 45,x to 45,x/46,xx mosaics was notably higher in a new york city series of embryonic and fetal deaths, 13.5 to 1, than in living individuals reported to the new york state chromosome registry, 3.6 to 1. the ratios of 45,x cases to those w ...19836683706
hemagglutination patterns of aeromonas spp. in relation to biotype and source.aeromonas spp. show patterns of hemagglutination with human group o cells in the presence of fucose, galactose, and mannose. these patterns are related to biotype as well as to the source of isolates. there was good correlation between hemagglutination pattern and the presence of diarrhea among strains isolated in western australia, which was the only source with adequate data for classification of children with an without diarrhea. most of the environmental and other nonfecal isolates produced ...19846690466
the case of baby jane doe: child abuse or unlawful federal intervention? 19846742262
massive swelling of the foot in a 63-year-old man. 19826815347
rates of mutant structural chromosome rearrangements in human fetuses: data from prenatal cytogenetic studies and associations with maternal age and parental mutagen exposure.in 27,225 prenatal cytogenetic studies of amniotic fluid reported to the new york state chromosome registry and the united states interregional chromosome register system, there were 61 cases with a structural chromosomal abnormality not known inherited, a rate per 1,000 of 2.24. of these 33, 1.21 per 1,000 were known de novo and nonmosaic; consequently, the rate of events resulting from germinal mutation is highly likely to be between these two limits. the rates per 1,000 of unbalanced abnormal ...19836823977
field epidemiologic studies of populations exposed to waste dumps.epidemiologic studies are required for assessing health risks related to toxic waste exposure. since the settings in which such studies must be performed are extremely diverse, epidemiologic approaches must be versatile. for any particular study, three fundamental requirements are to assess what toxic materials are present, understand how human exposure may occur, and objectively measure possible biologic effects. in assessing links between exposure and disease, epidemiologists must be particula ...19836825633
influenza vaccines in children. comparison of new cetrimonium bromide and standard ether-treated vaccines.we compared a new cetrimonium bromide (ctab) subunit vaccine with a conventional polysorbate (tween)-ether split-product vaccine in 63 children and young adults. the vaccines each contained influenza a/bangkok/79, a/brazil/78, b/singapore/79; two doses were given one month apart. among persons initially seronegative for a/bangkok/79, the geometric mean antibody titer rose to more than 100 following one dose of vaccine, while those initially seropositive had titers of greater than 200 after one d ...19836847954
cancer epidemiology: shortcomings and possibilities.the development of the concepts of initiators and promoters in carcinogenesis necessitates deliberations of evidence from human cancer epidemiology. recent arguments in favor of mortality data as a more reliable indicator of trends in cancer incidence than morbidity data collected from cancer registries are disputed. inconsistency in the use of data is pointed out. comparisons of data from cancer registration in denmark with those from connecticut and upstate new york show such congruity that it ...19836873023
obtaining informed consent in the teaching nursing home.the authors observed attempts to obtain informed consent for clinical research at the jewish institute for geriatric care. one study entailed the use of venipuncture, urine collections, urethral catheterizations, and antibiotic therapy. the other required that venipunctures and lumbar punctures be performed on dementia patients. patients and families were observed to be unwilling to consent to any procedure more invasive than venipuncture. poor recall and other physical and psychologic factors i ...19836886285
genetic polymorphism of human c4-binding protein.two different forms of human c4-bp, c4-bp a and c4-bp b, have been identified by isoelectric focusing (ief) of neuraminidase-treated edta-plasma samples. family studies demonstrate mendelian segregation of these forms, indicating that they are under gentic control. this conclusion is supported by ief analysis of the two variants purified by affinity chromatography. under completely denaturing conditions, c4-bp b was found to be composed of two subunits that focused at different ph, whereas c4-bp ...19836886425
human babesiosis. clinical and therapeutic considerations.during a two-month period, six patients from eastern long island were identified as having babesia microti infection. diagnosis was based on characteristic blood smears, hamster inoculation, or both. symptom duration ranged from 19 to 24 days in five patients. the sixth patient, who had previously undergone splenectomy, had a more severe and prolonged illness. no specific therapy was administered to five patients. the patient who had had a splenectomy was treated with chloroquine, quinine, penta ...19826890585
association between age, blood lead concentration, and serum 1,25-dihydroxycholecalciferol levels in children.serum levels of 1,25-dihydroxycholecalciferol (1,25-cc), the form of vitamin d active in stimulating intestinal absorption of calcium, phosphorus, and lead, were determined in 177 human subjects ages 1 to 16 yr. significant negative association (r = -0.88) was observed between serum 1.25-cc levels and blood lead concentrations over the entire range of blood lead levels, 12 to 120 micrograms/dl. adolescents ages 11 to 16 yr had serum 1,25-cc levels higher than those observed among children 10 yr ...19826896257
human blood utilization in the new york--new jersey metropolitan area. 19806932238
latter-day psychiatry for the common man. 19816942268
serum cholesterol and human colon cancer.comparison of serum cholesterol levels in a matched case-control study indicates that patients with colon cancer have serum cholesterol levels lower than those of controls. in 133 pairs matched by age and sex, serum cholesterol levels were 188 +/- 42 mg/dl for cases and 213 +/- 42 mg/dl for controls (paired t-test = 5.08; p less than 0.001). following stratification by tumor stage, significant differences in serum cholesterol levels persisted between cases with advanced tumors (duke's classifica ...19816943369
a case of keratitis due to acanthamoeba in new york, new york, and features of 10 cases.a man in new york, new york, contracted keratitis caused by acanthamoeba castellanii. the diagnosis was delayed because amoebae were not initially suspected as the infectious organism. the culture isolate and the amoebae in corneal sections were identified as a. castellanii by immunofluorescence using antiserum to plasma membranes of this species. with the rapid agar disk diffusion method, the amoebae were shown to e susceptible to pimaricin (0.5%) and resistant to greater than 1,000-micrograms/ ...19816972421
a sudden decline in ampicillin resistance in salmonella typhimurium.starting in 1975, an abrupt decline in ampicillin resistance of salmonella typhimurium (the most common and antibiotic-resistant serotype) occurred in new york city. the present lower rate of 5% to 7.9% at our hospitals represents a return to the 1965 level. at the same time, the ampicillin resistance in s typhimurium from calves and other farm animals from upper new york state, which has been rising since 1972, has reached 75%. substantial differences between levels of resistance in escherichia ...19806985988
fragments from an autobiography. 19806991623
margaret sanger: birth control's successful revolutionary.the year 1979 marked the centennial of margaret sanger, birth control pioneer. sanger worked to secure two new human rights: the right to decide whether to have a child and the right of a child to be wanted. beginning in 1873, antipornography crusader anthony comstock lobbied through congress and the state legislatures laws forbidding the distribution of contraceptive devices and even information. he equated these with erotic postcards as "obscene, lewd, lascivious, filthy, indecent and disgusti ...19806992603
frank netter: the man, the artist, the surgeon. 19817010057
ten-year experience with human pancreatic transplantation. 19807013210
the william allan memorial award: presented to walter f. bodmer, phd, at the annual meeting of the american society of human genetics new york, september 24-27, 1980. 19817027789
an epidemiologic evaluation of leprosy in new york city.leprosy is a transmissible disease that is propagated from human to human. at the us public health service hospital, new york city, the number of new leprosy cases per year during the 1970s was about three times greater than in the previous decade. this review of our 100 most recent leprosy patients shows that 60% were of the lepromatous and borderline lepromatous type. ninety-nine of the patients were foreign born, originating in more than 26 countries. this emphasizes that, at this time, the l ...19827087061
nih urged to act on germ war.in response to reports that scientists have been approached by the military about the possibility of using cloning techniques to produce defensive biological warfare agents, dr. richard goldstein of harvard medical school and dr. richard novick of the public health research institute of new york city have asked the recombinant dna advisory committee to amend the nih recombinant dna guidelines to ban "the construction of biological weapons by molecular cloning."19827088135
were tuskegee & willowbrook 'studies in nature'?the author examines and rejects the claims of researchers involved in two well-known studies, the tuskegee study of untreated syphilis in poor blacks and the willowbrook experiments with hepatitis in institutionalized retarded children, that these were "studies in nature" in which the researchers were only passive observers of a natural phenomenon. he further argues that the research designs were unethical and that, in attempting to take advantage of conditions of overwhelming social deprivatio ...19827096065
the woman who died in a box. commentary.hopper and kittrie comment separately on the case of a homeless woman who froze to death on a city street. they discuss the extent to which society is obligated to intervene in protecting persons in need of care who refuse to accept intervention, balancing the demands of personal autonomy against communal responsibility. both commentators agree that new york city's protective services law, since streamlined, proved ineffective in its initial application. after almost two weeks of rejected off ...19827107235
the woman who died in a box. commentary. 19827107236
controversy at love canal.a cancer researcher reviews the events surrounding the toxic waste contamination at love canal with emphasis on the political nature of the controversy about its health impact. antagonism between the community and the new york state department of health was fueled by several factors: the state's awareness that it gained from delay in investigation, disagreement on health problems to be studied, control over the information gathering process, silencing of opposition opinion, and the violation of ...19827107238
brugia infection in northern ohio.a new case of infection with brugia sp. is recorded from northern ohio, increasing the geographical range of this zoonosis, known previously in new england, new york and new jersey. the patient, a 53-year-old man, had a 7-year history of malignant fibrous histiocytoma of the spermatic cord, for which he received intense chemo- and radiotherapy. the worm found was alive at the time of fixation, allowing a description of the parasite in cross sections.19827149100
[the traits theory in longitudinal life span research. partial report of a workshop].during the international workshop on 'life span and change in a gerontological perspective' (9-12 july, 1981) at the university of nijmegen, the netherlands, research data from the oakland growth study and the guidance study have been discussed. the second major contribution came from the longitudinal studies at the bonn university. these groups of researchers cover different periods in the life span, but both contribute to prediction and understanding of periods not under investigation. each of ...19827164133
strontium-90 in bone: a case study in age-dependent dosimetric modeling.there is an increasing need for age-dependent dosimetric models, and it would be desirable to develop these models in such a way that the uniformity and basic features of the standard man models are retained. unfortunately, available data concerning the age-dependent retention of nuclides would rarely permit the identification of compartments, uptake fractions, and clearance times using the empirical fitting methods that characterize the development of many adult models. however, in cases where ...19827174326
serosurvey for human babesiosis in new york.healthy individuals at high risk of exposure to ticks were surveyed to determine the prevalence and incidence of asymptomatic babesiosis on shelter island, new york, during a single transmission season. paired sera obtained in june and october 1978 were tested for antibodies to babesia microti by indirect immunofluorescence. point prevalence values of 4.4% in june and 6.9% in october were obtained. six of 102 persons tested in both months showed at least a fourfold rise in titer of antibodies to ...19807189538
human babesiosis in north america. 19807189910
babesiosis in post-splenectomy hosts.two persons who had been splenectomized later contracted babesiosis, one on cape cod and one near islip, long island, areas where human cases of babesiosis had not been previously identified. one of the patients received pentamidine, but parasitemia persisted after therapy. no deaths have been recorded for persons who had had splenectomies and were later infected with babesia microti. until more effective therapy is available, such patients should be treated conservatively.19807192058
biological variability of regional deposition of aerosol particles in the human respiratory tract.regional deposition of inhaled particles was studied experimentally for 9 health subjects breathing the same aerosol under the same breathing conditions in order to evaluate intersubject variability of regional deposition. a great intersubject variability of extrathoracic, tracheobronchial and alveolar deposition was found. the highest one was observed for particle deposition in the extrathoracic airways. this biological variability of regional deposition has to be taken into account for conside ...19817223643
the right to refuse treatment: ethical issues.to understand the emerging concept of the right to refuse treatment in mental institutions, several underlying ethical issues must be examined. for example, the right is limited by such factors as the competence of the patient, the distinction between apparent and real refusal of treatment, and the desirability of some balance between the state's police power and parens patriae power. the most difficult ethical problems arise when a mentally ill individual is competent and not dangerous, needs t ...19817227984
characteristics of yersinia enterocolitica and related species isolated from human, animal, and environmental sources.during a 4-year period, 4,448 human, animal, and environmental samples collected in new york state were tested for the presence of yersinia enterocolitica or related species. a total of 339 isolates were identified as yersinia and characterized according to source, species, biogroup, serogroup, and, in some instances, phage type. four new biogroups of y. intermedia were characterized. of 149 human isolates, 120 (80.5%) were identified as y. enterocolitica, and 29 were identified as either y. int ...19817287887
application of a time-space clustering methodology to the assessment of acute environmental effects on respiratory illnesses.a new methodology is proposed for the identification of environmental events of health significance. health indices measured on a daily basis at various location in a single geographical area are collected over time. first, the daily variations are examined to determine whether they reflect purely random variations or whether there are days on which there are extreme variations not plausibly explicable as random events. after such days are identified, the question of whether they occur only at a ...19817330366
sulfur oxides, particulates, and human mortality: synopsis of statistical correlations. 19807365147
cancer incidence and trihalomethane concentrations in a public drinking water system.four thousand two hundred fifty-five cases of esophageal, stomach, colon, rectal, bladder, and pancreatic cancer reported from erie county, ny between 1973 and 1976 were analyzed in terms of their relationship to type of water source, level of trihalomethane (thm) and various social and economic parameters. among white males, a significant positive correlation existed between pancreatic cancer incidence rates and thm level. no other significant correlations were observed. this research lends lit ...19807377424
fallout plutonium in human tissues from new york city. 19807394162
concurrent respiratory syncytial virus and influenza a infections in the institutionalized elderly and chronically ill.during a community outbreak of respiratory syncytial virus and influenza a/texas/77 infections, we investigated 71 cases of upper respiratory illness at a chronic disease hospital using a surveillance system plus viral and serologic studies. of the 32 patients with an etiologic diagnosis, seven had respiratory syncytial virus, 24 had influenza, and one had dual infections with respiratory syncytial virus and influenza. no definite etiologic diagnosis was made in the remaining 39 patients. a comp ...19807396314
humane methodology and conservation of species in maintaining a primate animal laboratory for biomedical experimentation: twenty years experience.the "3 r's", i.e., reduction of numbers, refinement of techniques aimed at avoiding or diminishing pain and suffering, and replacement of primate animal use (or animal use) whenever possible has been our policy for the past twenty years. lemsip is an inter-institutional, biomedical laboratory primarily serving physicians with clinical human patient responsibilities, and the research aimed at improving human health. the majority of its users are from new york and the northeastern u.s. area, but i ...19807399149
implementation or regulations for the protection of man and animals used in biomedical research at a united states' school of medicine.implementation of the present regulations of animal experimentation compared to use of human subjects in a setting of a large medical school including the impact on administrative systems involved in the compliance and monitoring process as well as cost of implementation.19807399150
radiation and host factors in human thyroid tumors following thymus irradiation. 19807410071
biochemical characteristics and virulence of environmental group f bacteria isolated in the united states.bacteria phenotypically resembling aeromonas hydrophila, but requiring nacl for growth, have been isolated form the new york bight. the bacteria proved to be identical to group f organisms isolated from cases of human diarrhea in indonesia and bangladesh. anaerogenic strains initiated responses in y-1 tissue culture and rabbit ileal loop, consistent with those associated with cytotoxin- and enterotoxin-producing aeromonas spp. strains. separation on the basis of production of gas from glucose by ...19807425623
midlife women in college sexuality classes.47 women between the ages of 35 and 60 were enrolled in human sexuality classes of queens college in their (ace) adult collegiate education program. at the outset of the semester, students filled in a personal data questionnaire which provided characteristics data and each wrote an anonymous paper about their sexual attitudes concerning themselves; at the conclusion another such paper was written about continuing concerns about personal sexuality. problems which were most pervasive at the begi ...19807430494
the sources and routes of childhood chemical exposures. 19807431184
rates of 47, + 13 amd 46 translocation d/13 patau syndrome in live births and comparison with rates in fetal deaths and at amniocentesis.trisomy 13 (patau syndrome) is rare in newborns. data on rates in 167,774 live births from 17 separate studies are reviewed, and the following pooled rates found for: (1) 47,trisomy 13, 8.3 x 10(-5) (1/12,000); and (2) 46, (d/13 robertsonian translocations), 4.2 x 10(-5) (1/24,000)--mutants, 1.2 x 10(-5) (1/80,000) to 1.8 x 10(-5) (1/56,000); and familial cases, 2.4 x 10(-5) (1/42,000) to 3.0 x 10(-5) (1/33,000). the rate of trisomy 13 (47, + 13) in liveborns (ignoring possible biases in studies ...19807446526
neurological correlates of fetal cocaine exposure: transient hypertonia of infancy and early childhood.to assess whether prenatal cocaine exposure has any long-term effects on neurodevelopment.19957491223
failure to identify human immunodeficiency virus-seropositive newborns: epidemiology and enrollment patterns in a predominantly white, nonurban setting.to describe the epidemiology of newborn seroprevalence for human immunodeficiency virus (hiv) in a predominantly white, nonurban population, and to determine the factors associated with enrollment at a regional pediatric acquired immunodeficiency syndrome (aids) center serving that population.19957491225
genotypic and phenotypic characterization of borrelia burgdorferi isolated from ticks and small animals in illinois.we have characterized 33 isolates of borrelia burgdorferi from northern illinois (32 isolates) and wisconsin (1 isolate) representing the largest series of midwestern isolates investigated to date. the techniques used for molecular analysis of strains included (i) genospecies typing with species-specific pcr primers, (ii) plasmid profiling by pulsed-field gel electrophoresis of total genomic dna, (iii) large-restriction-fragment pattern (lrfp) analysis by pulsed-field gel electrophoresis of mlui ...19957494019
human exposure to toxic materials. the new york-new jersey metropolitan region. 19957500968
developmental and service needs of school-age children with human immunodeficiency virus infection: a descriptive study.to describe the developmental functioning and service needs of a group of school-age children with human immunodeficiency virus (hiv) infection.19947526329
quality with a human face? the samuels planetree model hospital unit.hospitals across the country are seeking to restructure the delivery of care. planetree, an international consumer health care organization, works with hospitals to cultivate educated health care consumers and to create caring inpatient environments. this article gives an overview of planetree's philosophy, examines staff and patient satisfaction, and contrasts planetree with total quality management (tqm)/continuous quality improvement (cqi) as practiced at one hospital. planetree's philosophy: ...19957550786
characteristics of hiv-positive chronically mentally ill inpatients.the growing population of chronically mentally ill persons who are hiv-positive or who have aids has not yet been adequately studied. we describe the entire population of known hiv-positive inpatients in a state psychiatric center in new york city. in this sample, the typical patient with known hiv infection is as likely to be a man as a woman and is a member of an ethnic minority group. hiv-positive patients had multiple risks for hiv infection including injecting drug use (idu), sex with idu p ...19957568528
comparison of methods of estimating the mother-to-child transmission rate of human immunodeficiency virus type 1 (hiv-1). new york city perinatal hiv transmission collaborative study group.four methods of estimating mother-to-child transmission rates of human immunodeficiency virus type 1 (hiv-1), based on the 1992 ghent workshop, were compared in a multicenter new york city prospective cohort study in 1986-1992. of 833 infants born to women at risk of hiv-1 infection, 388 were born hiv-1 seropositive and 445 were hiv-1 seronegative. the four methods, the antibody only, indirect, direct, and virologic methods, yielded transmission rate estimates of 19-25%, classifying 59-89% of th ...19957572941
women at a sexually transmitted disease clinic who reported same-sex contact: their hiv seroprevalence and risk behaviors.this study compares characteristics, behaviors, and human immunodeficiency virus (hiv) infection in women who reported same-sex contact and women who had sex only with men.19957573619
transmission of multidrug-resistant tuberculosis in a large urban setting.multidrug resistance has become an increasingly important problem in the control and prevention of tuberculosis in large urban centers. although several small outbreaks of multidrug-resistant (mdr) tuberculosis in new york city have been reported, the increase in the number of cases is not fully explained by these recognized outbreaks, and the modes of transmission have not been clearly delineated. transmission patterns of mdr tuberculosis in new york city, therefore, were studied by stratifying ...19957599845
prenatal care of hiv-infected women: analysis of a large new york state cohort.we examined the effect of methadone treatment, duration of medicaid enrollment during pregnancy, and other maternal characteristics on receipt of prenatal care by 2,254 women infected with human immunodeficiency virus (hiv) delivering a singleton in new york state from 1985 through 1990. data were obtained from the new york state medicaid hiv/aids research data base and vital statistics records. adequacy of the number of prenatal visits reported by the mother on vital statistics records was asse ...19957600104
racial differences in care among hospitalized patients with pneumocystis carinii pneumonia in chicago, new york, los angeles, miami, and raleigh-durham.while strategies for medical care for human immunodeficiency virus-related pneumocystis carinii pneumonia (pcp) are well established, racial variations in care have not been evaluated.19957618980
the effectiveness of video-based interventions in promoting condom acquisition among std clinic patients.this study examined the effectiveness of video-based patient education interventions on promoting condom use among men and women seeking services at a large public std clinic in new york city.19957624818
a community-wide outbreak of hepatitis a: risk factors for infection among homosexual and bisexual men.to assess risk factors for hepatitis a infection among homosexual and bisexual men during a community-wide outbreak of hepatitis a in new york city.19957625417
injuries associated with self-unloading forage wagons--new york, 1991-1994.in new york, an estimated 3600 injuries occur each year to farmers operating farm machines (1). in october 1993, the occupational health nurses in agricultural communities (ohnac) program in the new york state department of health received a report of a man who sustained severe injuries when he became entangled in the power take-off (pto) driveline to a self-unloading forage wagon. subsequent investigation by ohnac identified four additional similar incidents in new york that occurred during sep ...19957630338
infection control, human immunodeficiency virus, and home health care: ii. risk to the caregiver. 19957639407
sex, drugs, and syringe exchange in new york city: women's experiences.the sex and drug human immunodeficiency virus (hiv) risk factors of drug-injecting women participating in new york city syringe exchange programs were studied and racial/ethnic differences examined. african-american women reported injecting least frequently and had lower rates of injecting with borrowed or used syringes. women attending syringe exchange reported high levels of sexual risk behavior, and syringe exchange provides an opportunity for a sexual risk reduction intervention. women were ...19957657943
an evaluation of community-based hiv services for women in new york state.the proportion of women in new york state diagnosed with acquired immune deficiency syndrome (aids) is increasing dramatically. in 1987, only 12% of cumulative aids cases in new york were among women; by 1993, 26% of new cases of aids were. this evaluation describes community-based hiv programs that provide services to women in new york state and are funded by the state department of health's aids institute. the evaluation assesses the success different programs have had in reaching and engaging ...19957657945
mosquito-transmitted malaria in new york city, 1993.in august, 1993, 3 cases of plasmodium falciparum malaria in people without recent travel histories or bloodborne exposure were reported in new york city. an epidemiological investigation confirmed the absence of risk factors for acquisition of malaria in two cases. the third case could not be definitively classified as locally acquired malaria because the patient had travelled to thailand two years before malaria was diagnosed. the 3 individuals lived in separate houses in the same neighbourhoo ...19957658873
human granulocytic ehrlichiosis--new york, 1995.since 1986, two human tickborne diseases caused by ehrlichia spp. have been recognized in the united states: human monocytic ehrlichiosis (hme), caused by e. chaffeensis, and human granulocytic ehrlichiosis (hge), caused by an agent closely related to e. equi (1,2). in june 1995, the westchester county (new york) department of health (wcdoh) received reports from physicians who were treating patients for suspected hge. in response, the wcdoh sent information to all primary-care physicians in wes ...19957662028
communitywide laboratory-based influenza surveillance focused on older persons, 1989-1992.we collected surveillance data as part of the medicare influenza vaccine demonstration to describe communitywide epidemiology of influenza, focusing on the elderly. laboratory-based surveillance was established in medical practices, hospitals, and nursing homes in a two-county demonstration in upstate new york. time course and intensity of epidemic influenza were compared between counties, between influenza a and b epidemics, and among several levels of surveillance involving elderly persons as ...19957662393
multidrug-resistant tuberculosis in patients without hiv infection.investigations of outbreaks of multidrug-resistant tuberculosis have found low rates of treatment response and very high mortality, and they have mainly involved patients with advanced human immunodeficiency virus (hiv) infection. for patients without hiv infection, one study reported an overall rate of response to treatment of 56 percent, and the mortality from tuberculosis was 22 percent. we investigated treatment response and mortality rates in 26 hiv-negative patients in new york with multid ...19957666876
knowledge and attitudes of healthcare workers about influenza: why are they not getting vaccinated?in a survey of employees at a chronic care psychiatric facility following an influenza outbreak, previous influenza vaccination (relative risk [rr], 69.7; 95% confidence interval [ci95], 25.2 to 192.4), age > or = 50 years (rr, 2.4; ci95, 1.3 to 4.5), and knowledge that vaccine does not cause influenza (rr, 2.3; ci95, 1.3 to 3.7) were the factors most predictive of current influenza vaccination. medical personnel were less likely than nonmedical employees to be vaccinated (rr, 0.5; ci95, 0.3 to ...19957673647
from the centers for disease control and prevention. human granulocytic ehrlichiosis--new york, 1995. 19957674488
antibodies to discontinuous or conformationally sensitive epitopes on the gp120 glycoprotein of human immunodeficiency virus type 1 are highly prevalent in sera of infected humans.we have used an indirect-capture enzyme-linked immunosorbent assay to quantitate the reactivity of sera from human immunodeficiency virus type 1 (hiv-1)-infected humans with native recombinant gp120 (hiv-1 iiib or sf-2) or with the gp120 molecule (iiib or sf-2) denatured by being boiled in the presence of dithiothreitol with or without sodium dodecyl sulfate. denaturation of iiib gp120 reduced the titers of sera from randomly selected donors by at least 100-fold, suggesting that the majority of ...19937678308
independent divergences in the cd4 binding site and v3 loop encoded in two seroprevalent ugandan hiv-1 clinical isolates.two major epitopes expressed in hiv-1 have been recently shown to play a central role in virus neutralization. one of these important specificities is a type-specific or group-specific, principal neutralizing determinant (pnd) located in the v3 loop of gp120. the other is a more broadly neutralizing determinant associated with the cd4 binding site. structural and serological studies of the variation in these epitopes have become important in vaccine research. this report describes the analysis o ...19937686222
ipro's health care quality improvement program.ipro is a peer-review organization in new york state that functions under a contract with the health care financing administration (hcfa) of the u.s. department of health and human services for assuring quality of care for medicare patients. in 1993, ipro initiated its health care quality improvement program (hcqip). the purpose of this program is to develop information on patterns of care and outcomes, to share this with health care providers, and in so doing effect measurable improvements in c ...19957699109
condom use among criminally-involved adolescents.condom use was studied for 421 sexually active, minority male adolescents who were currently in jail in new york city. over three-quarters of the youths were users of alcohol and marijuana and about one-quarter were users of cocaine or crack, but drug injectors were rare. in the six months before arrest they had multiple sexual partners and about one-third had engaged in anal intercourse. inconsistent condom use was the norm, with 17% reporting that they never used condoms and only 15% reporting ...19947711092
newborn human immunodeficiency virus testing in new york: a legislative quandary. 19957735416
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