| species diversity and relative abundance of phlebotomine sand flies (diptera: psychodidae) on three army installations in the southern united states and susceptibility of a domestic sand fly to infection with old world leishmania major. | leishmania infections in american veterans of iraq and afghanistan have raised concern that veterans could serve as reservoirs of old world parasites for domestic vector populations. a survey of sand flies on three u.s. army facilities in the southern united states was conducted to identify potential vectors. five species, including two new state records, are reported for fort hood, tx. very few flies were detected in fort bragg, nc. large numbers of a man-biting species, lutzomyia shannoni, wer ... | 2009 | 19960830 |
| progress in understanding the human immune responses to mycobacterium tuberculosis. | development of an effective vaccine against tuberculosis hinges on an improved understanding of the human immune response to mycobacterium tuberculosis. work in this area at the university of texas health science center at tyler has led to advances in four areas: (1) natural killer cells contribute to innate immunity by lysing m. tuberculosis-infected mononuclear phagocytes, and to adaptive immunity by enhancing the cd8+ t-cell effector function and inhibiting expansion of t regulatory cells; (2 ... | 2009 | 20006306 |
| pattern of oseltamivir ingestions reported to texas poison centers. | during serious influenza outbreaks, the number of oseltamivir exposures reported to poison centers might be expected to increase. this investigation describes the pattern of oseltamivir ingestions reported to texas poison centers during 2000-2008. of 298 total ingestions, 91.9% occurred in december-march, 76.8% involved patients aged 0-19 years, 72.5% resulted from therapeutic error, 90.0% were managed on-site, and 80.0% had no effect. the most frequently reported adverse clinical effects were v ... | 2010 | 20015912 |
| spatial distribution of lead concentrations in urban surface soils of new orleans, louisiana usa. | immediately following hurricane katrina concern was raised over the environmental impact of floodwaters on the city of new orleans, especially in regard to human health. several studies were conducted to determine the actual contaminant distribution throughout the city and surrounding wetlands by analyzing soil, sediment, and water for a variety of contaminants including organics, inorganics, and biologics. preliminary investigations by the institute of environmental and human health at texas te ... | 2010 | 20054703 |
| texas surgeon agrees to treat hiv/aids patients. hhs office for civil rights announces agreement. | | 2009 | 20066752 |
| factors contributing to suboptimal vaccination against influenza: results of a nationwide telephone survey of persons with cardiovascular disease. | vaccination against influenza averts cardiovascular events and is recommended for all patients with coronary heart disease. because data were unavailable regarding vaccination rates among such patients' household contacts, we sought to estimate the rate of influenza vaccination in persons with cardiovascular disease and their contacts. in 2004, we conducted a random, nationwide telephone survey of 1,202 adults (age, > or = 18 yr) to ascertain knowledge, attitudes, and behaviors regarding influen ... | 2009 | 20069079 |
| partitioning of polybrominated diphenyl ethers (pbdes) in serum and milk from the same mothers. | we and others have previously described partitioning of chemicals, including polychlorinated-p-dioxins, dibenzofurans, and biphenyls in different types of human tissues and fluids, including blood and milk. additionally, we previously reported the blood to milk partitioning of polybrominated diphenyl ethers (pbdes) in a group of 11 women. partitioning is of importance in understanding the toxicokinetics of these compounds and also in clinical medicine in improving estimates of levels in differen ... | 2010 | 20079522 |
| survival of texas infants born with trisomies 21, 18, and 13. | trisomies 21, 18, and 13 are the three most common trisomies among infants who survive to 20 weeks gestation or more. overall information about birth prevalence, natural history, and mortality for all three trisomies is well defined, but information about ethnic-specific rates is limited. only a few studies have examined mortality rates of trisomies 18 and 13 because so few cases are liveborn and most have very short life spans. this study assessed ethnic-specific population-based survival proba ... | 2010 | 20082470 |
| it's your game: keep it real: delaying sexual behavior with an effective middle school program. | this study tested the effects of a theory-based, middle-school human immunodeficiency virus, sti, and pregnancy prevention program, it's your game: keep it real (iyg), in delaying sexual behavior. we hypothesized that the iyg intervention would decrease the number of adolescents who initiated sexual activity by the ninth grade compared with those in the comparison schools. | 2010 | 20113923 |
| companion animal knowledge, attachment and pet cat care and their associations with household demographics for residents of a rural texas town. | this cross-sectional telephone survey explored companion animal attachment and knowledge as well as cat care of residents in a small texas town. the survey included 441 residents of randomly selected households (55% response rate). dogs were owned by 48% of households and cats by 29%. companion animal ownership was associated with being 25-44 years old, being anglo, having an income over $85,000/year, and feeding unowned cats. more knowledge about animals was associated with being any age except ... | 2010 | 20122744 |
| a modest proposal in response to rhodes and schiano. | | 2010 | 20131166 |
| community health development: a strategy for reinventing america's health care system one community at a time. | the purpose of this article is to propose a set of ideas for reinventing america's health care system, one community at a time. community health development is proposed as a strategy and approach to population health improvement, the ultimate goal of health care reform. the practice of community health development, particularly the partnership approach, provides guidance about how this approach might be employed as a national health care reform strategy. examples of two communities successfully ... | 2010 | 20135230 |
| hiv/sti risk among male mexican immigrants in dallas, texas: findings from a pilot study. | rates of hiv and stis are higher among latinos than the general u.s. population. a number of factors place latino immigrants at particularly high risk. 128 male mexican immigrants in dallas, texas completed personal interviews. we measured the prevalence of hiv/sti risk factors and identified sociodemographic and behavioral characteristics associated with higher risk. 9% of the total sample had 3 or more sexual partners in the past year. 5% had sex with a commercial sex worker (csw). 11% had sex ... | 2010 | 20157851 |
| family-based study shows heterogeneity of a susceptibility locus on chromosome 8q24 for nonsyndromic cleft lip and palate. | nonsyndromic cleft lip with or without cleft palate is a common birth defect. although a number of susceptibility loci have been reported, replication has often been lacking. this is likely due, in part, to the heterogeneity of datasets and methodologies. two independent genome-wide association studies of individuals of largely western european extraction have identified a possible susceptibility locus on 8q24.21. | 2010 | 20196142 |
| three-dimensional comparison of facial morphology in white populations in budapest, hungary, and houston, texas. | the aim of this study was to assess the use of 3-dimensional facial averages in determining facial morphologic differences in 2 white population groups. | 2010 | 20197183 |
| murine typhus in austin, texas, usa, 2008. | in august 2008, texas authorities and the centers for disease control and prevention investigated reports of increased numbers of febrile rash illnesses in austin to confirm the causative agent as rickettsia typhi, to assess the outbreak magnitude and illness severity, and to identify potential animal reservoirs and peridomestic factors that may have contributed to disease emergence. thirty-three human cases of confirmed murine typhus were identified. illness onset was reported from march to oct ... | 2010 | 20202415 |
| borrelia, ehrlichia, and rickettsia spp. in ticks removed from persons, texas, usa. | data regarding the type, frequency, and distribution of tick-borne pathogens and bacterial agents are not widely available for many tick species that parasitize persons in the southern united states. we therefore analyzed the frequency and identity of pathogens and bacterial agents in ticks removed from humans and subsequently submitted to the texas department of state health services, zoonosis control program, from october 1, 2004, through september 30, 2008. the data showed associations of bac ... | 2010 | 20202419 |
| improving influenza immunization in pregnant women and healthcare workers. | to evaluate the effect of several strategies to increase influenza immunization in a multispecialty clinic. | 2010 | 20225916 |
| estrangement factors associated with addiction to alcohol and drugs among homeless youth in three u.s. cities. | substance use is highly prevalent among homeless, street-involved young people. societal estrangement is often associated with substance use, particularly among this population. the current study sought to identify four domains of social estrangement (disaffiliation, human capital, identification with homeless culture, and psychological dysfunction) in relation to alcohol and drug addiction. homeless young adults were recruited from three disparate urban areas: los angeles, ca (n=50), austin, tx ... | 2010 | 20299098 |
| warty-basaloid carcinoma: clinicopathological features of a distinctive penile neoplasm. report of 45 cases. | most penile cancers are squamous cell carcinomas, but there are several subtypes with different clinicopathologic, viral, and outcome features. we are presenting 45 cases of a distinctive morphological variant of penile squamous cell carcinoma composed of mixed features of warty and basaloid carcinomas. this tumor was earlier recognized in a recent viral study and showed a high association with human papillomavirus infection. however, clinicopathologic features are not well known. in this multi- ... | 2010 | 20305615 |
| household transmission of pandemic (h1n1) 2009, san antonio, texas, usa, april-may 2009. | to assess household transmission of pandemic (h1n1) 2009 in san antonio, texas, usa, during april 15-may 8, 2009, we investigated 77 households. the index case-patient was defined as the household member with the earliest onset date of symptoms of acute respiratory infection (ari), influenza-like illness (ili), or laboratory-confirmed pandemic (h1n1) 2009. median interval between illness onset in index and secondary case-patients was 4 days (range 1-9 days); the index case-patient was likely to ... | 2010 | 20350377 |
| glycemic control in pediatric type 1 diabetes: role of caregiver literacy. | poorly controlled diabetes may occur because caregivers of children with type 1 diabetes fail to comprehend provided diabetes education. we hypothesized that poorly controlled diabetes is associated with lower literacy/numerical skills of caregivers of children with type 1 diabetes. | 2010 | 20368322 |
| use of 3-dimensional surface acquisition to study facial morphology in 5 populations. | the aim of this study was to assess the use of 3-dimensional facial averages for determining morphologic differences from various population groups. | 2010 | 20381762 |
| considerations for hospital approval of human participant research. | hospitals often accept as sufficient the federal requirement that human participant research studies have institutional review board (irb) review and approval, but irbs usually do not consider many practical matters that arise in the implementation and operation of an interventional clinical trial in the complex environment of the modern acute care hospital. | 2010 | 20394012 |
| acute myeloid leukemia with t(9;11)(p21-22;q23): common properties of dysregulated ras pathway signaling and genomic progression characterize de novo and therapy-related cases. | we compared pathogenetic features of 32 de novo and 29 therapy-related (t) t(9;11)(p21-22;q23)/mllt3-mll acute myeloid leukemia (aml) cases to identify progression factors and to assess whether distinction between these manifestations is warranted. mllt3-mll rearrangement was commonly the sole karyotypic abnormality at diagnosis, with many secondary chromosomal changes emerging at relapse in both subgroups. ras point mutations were common in both groups (overall, 18/50 [36%]) and associated with ... | 2010 | 20395514 |
| socioeconomic factors affecting local support for black bear recovery strategies. | there is global interest in recovering locally extirpated carnivore species. successful efforts to recover louisiana black bear in louisiana have prompted interest in recovery throughout the species' historical range. we evaluated support for three potential black bear recovery strategies prior to public release of a black bear conservation and management plan for eastern texas, united states. data were collected from 1,006 residents living in proximity to potential recovery locations, particula ... | 2010 | 20401658 |
| enrollment in outpatient care among newly released prison inmates with hiv infection. | although many prisoners infected with human immunodeficiency virus (hiv) initiate and adhere to treatment regimens while incarcerated, the benefits of in-prison therapy are frequently lost after community reentry. little information is available on the percentage of released inmates who establish community-based hiv outpatient treatment in a timely fashion. we sought to determine the proportion of hiv-infected texas prison inmates who enrolled in an hiv clinic within 90 days after release and to ... | 2010 | 20408389 |
| spread of adenovirus to geographically dispersed military installations, may-october 2007. | in mid-may 2007, a respiratory disease outbreak associated with adenovirus, serotype b14 (ad14), was recognized at a large military basic training facility in texas. the affected population was highly mobile; after the 6-week basic training course, trainees immediately dispersed to advanced training sites worldwide. accordingly, enhanced surveillance and control efforts were instituted at sites receiving the most trainees. specimens from patients with pneumonia or febrile respiratory illness wer ... | 2010 | 20409365 |
| high dietary intake of prebiotic inulin-type fructans in the prehistoric chihuahuan desert. | archaeological evidence from dry cave deposits in the northern chihuahuan desert reveal intensive utilisation of desert plants that store prebiotic inulin-type fructans as the primary carbohydrate. in this semi-arid region limited rainfall and poor soil conditions prevented the adoption of agriculture and thus provides a unique glimpse into a pure hunter-forager economy spanning over 10 000 years. ancient cooking features, stable carbon isotope analysis of human skeletons, and well-preserved cop ... | 2010 | 20416127 |
| unborn children as constitutional persons. | in roe v. wade, the state of texas argued that "the fetus is a 'person' within the language and meaning of the fourteenth amendment." to which justice harry blackmun responded, "if this suggestion of personhood is established, the appellant's case, of course, collapses, for the fetus' right to life would then be guaranteed specifically by the amendment." however, justice blackmun then came to the conclusion "that the word 'person,' as used in the fourteenth amendment, does not include the unborn ... | 2010 | 20443281 |
| heart-type fatty acid binding protein is an independent predictor of death and ventricular dysfunction after coronary artery bypass graft surgery. | heart-type fatty acid binding protein (hfabp) functions as a myocardial fatty acid transporter and is released into the circulation early after myocardial injury. we hypothesized that hfabp is superior to conventional cardiac biomarkers for predicting early perioperative myocardial injury after coronary artery bypass graft (cabg) surgery. | 2010 | 20457766 |
| bat guano virome: predominance of dietary viruses from insects and plants plus novel mammalian viruses. | bats are hosts to a variety of viruses capable of zoonotic transmissions. because of increased contact between bats, humans, and other animal species, the possibility exists for further cross-species transmissions and ensuing disease outbreaks. we describe here full and partial viral genomes identified using metagenomics in the guano of bats from california and texas. a total of 34% and 58% of 390,000 sequence reads from bat guano in california and texas, respectively, were related to eukaryotic ... | 2010 | 20463061 |
| late hiv diagnosis in houston/harris county, texas, 2000-2007. | this cross-sectional study aimed to evaluate the prevalence and predictive factors associated with late hiv diagnoses in houston, texas using surveillance data. study subjects were houston/harris county residents, 13 years or older, diagnosed with hiv and reported to the houston department of health and human services. late hiv diagnosis was defined as an aids diagnosis within three months of an hiv diagnosis. logistic regression was used to investigate the association between late hiv diagnoses ... | 2010 | 20467939 |
| a returning traveler with fever. | active duty military personnel and civilian government employees are at risk for exposure to a variety of pathogens as they meet their mission requirements throughout the world. when they present with a systemic disease, the clinician must entertain a broad differential diagnosis due to the multitude of infectious, neoplastic, and noninfectious inflammatory disorders that can have similar clinical presentations. since treatment varies significantly, and lack of appropriate therapy may be deadly, ... | 2010 | 20486510 |
| coding of influenza a h1n1 virus calls received by texas poison centers. | the utilization of poison center data for research and surveillance depends on the complete and accurate coding of the data. | 2010 | 20507247 |
| pulsed-field gel electrophoresis for salmonella infection surveillance, texas, usa, 2007. | to identify sources of transmission for area clusters, in 2007 the houston department of health and human services conducted an 8-month study of enhanced surveillance of salmonella infection. protocol included patient interviews and linking the results of interviews to clusters of pulsed-field gel electrophoresis patterns detected by the local pulsenet laboratory. | 2010 | 20507752 |
| primary language and cultural background as factors in resident burnout in medical specialties: a study in a bilingual us city. | the aim of this study was to identify the degree of burnout among resident physicians enrolled in seven postgraduate training programs at texas tech university health sciences center (ttuhsc), paul l. foster school of medicine, el paso, texas, as it related to residents' age, gender, marital status, number of hours worked per week, primary language, race/ethnicity, and cultural background. | 2010 | 20531049 |
| blood transfusions in critical care: improving safety through technology & process analysis. | a multidisciplinary safety initiative transformed blood transfusion practices at st. luke's episcopal hospital in houston, texas. an intense analysis of a mistransfusion using the principles of a just culture and the process of cause mapping identified system and human performance factors that led to the transfusion error. multiple initiatives were implemented including technology, education and human behaviour change. the wireless technology of pyxis transfusion verification by carefusion is ef ... | 2010 | 20541066 |
| nicotinic acetylcholine receptor region on chromosome 15q25 and lung cancer risk among african americans: a case-control study. | genome-wide association studies of white persons with lung cancer have identified a region of extensive linkage disequilibrium on chromosome 15q25.1 that appears to be associated with both risk for lung cancer and smoking dependence. because studying african american persons, who exhibit lower levels of linkage disequilibrium in this region, may identify additional loci that are associated with lung cancer, we genotyped 34 single-nucleotide polymorphisms (snps) in this region (including loc12368 ... | 2010 | 20554942 |
| novel application of a statistical technique, random forests, in a bacterial source tracking study. | in this study, data from bacterial source tracking (bst) analysis using antibiotic resistance profiles were examined using two statistical techniques, random forests (rf) and discriminant analysis (da) to determine sources of fecal contamination of a texas water body. cow trap and cedar lakes are potential oyster harvesting waters located in brazoria county, texas, that have been listed as impaired for bacteria on the 2004 texas 303(d) list. unknown source escherichia coli were isolated from wat ... | 2010 | 20566209 |
| poison center surveillance data: the good, the bad and ... the flu. | poison center data are increasingly used by state health departments and the centers for disease control and prevention for public health surveillance. forrester and colleagues evaluated the ability of 6 texas poison centers covering a population of 24 million to accurately code and report the number of h1n1 calls received over a 5-month period. | 2010 | 20586572 |
| pasa la voz (spread the word): using women's social networks for hiv education and testing. | pasa la voz (spread the word) is a human immunodeficiency virus (hiv) prevention methodology inspired by respondent-driven sampling (rds) that uses social networks to access hard-to-reach populations. as field testing showed the approach to be efficacious among at-risk women in west texas and southern new mexico, we set out to evaluate the methodology in a mexican context. a local community organization, programa compañeros, first implemented a traditional one-on-one outreach strategy using prom ... | 2010 | 20597452 |
| nutritionally important starch fractions of rice cultivars grown in southern united states. | dietary starches can be classified into 3 major fractions according to in vitro digestibility as rapidly digestible (rds), slowly digestible (sds), and resistant starch (rs). literature indicates that sds and/or rs have significant implications on human health, particularly glucose metabolism, diabetes management, colon cancer prevention, mental performance, and satiety. in this study, the nutritionally important starch fractions (rds, sds, and rs) in cooked rice were assayed in vitro, making us ... | 2010 | 20629878 |
| enhancing adolescent brain development through goal-setting activities. | | 2010 | 20632662 |
| immunohistochemical detection of zap70 in chronic lymphocytic leukemia predicts immunoglobulin heavy chain gene mutation status and time to progression. | zeta-associated protein-70 (zap70) expression measured by flow cytometry has been proposed as a surrogate marker of the somatic mutation status of the immunoglobulin heavy chain variable region (ighv) genes in chronic lymphocytic leukemia. however, attempts to implement this approach in clinical flow cytometry laboratories have been problematic; many commercially available antibodies give unreliable results. assessment of zap70 protein expression by immunohistochemistry in chronic lymphocytic le ... | 2010 | 20657554 |
| the global view: issues affecting us production agriculture. | this paper discusses small events occurring among developing countries, particularly but not exclusively in asia, and their subsequent large impacts on net food exporting countries in the world, particularly, but not exclusively, located in the western hemisphere. a green revolution ii is underway as a result where the world's agricultural system will produce more (output) with less (inputs). agriculture will meet the rapidly growing demand for bio-based foods, fuels, feeds, and fiber while redu ... | 2010 | 20665304 |
| respiratory issues in beef and pork production: recommendations from an expert panel. | this paper summarizes "respiratory issues in confined feeding operations," a panel discussion at the agricultural safety and health council of america/national institute for occupational safety and health conference, "be safe, be profitable: protecting workers in agriculture," dallas/fort worth, texas, january 27-28, 2010. occupational exposure to confined animal feeding operations is associated with cough, wheezing, and shortness of breath. published data shows that 20% to 40% of hog confinemen ... | 2010 | 20665307 |
| livestock handling--minimizing worker injuries. | numerous hazards may occur on farms raising livestock. animal contact is often ranked as the first or second leading cause of injuries on the farm. in addition to direct trauma from the animal, other injuries may occur from injection of medications, chemical splashes from cleaning the facility, and repetitive motion injuries. exposures to toxic gases from decomposition of animal waste such as in manure pits and exposure to animal allergens may cause adverse health effects in humans. one addition ... | 2010 | 20665308 |
| ergonomic risks and musculoskeletal disorders in production agriculture: recommendations for effective research to practice. | musculoskeletal disorders (msds) are increasingly recognized as a significant hazard of agricultural occupation. in agricultural jobs with significant physical labor, msds are typically the most frequently reported injury. although not as lethal as tractor roll-overs, msds can result in disability, lost work time, and increased production costs. msds increase production costs as a result of worker absence, medical and insurance costs, decreased work capacity, and loss of employees to turnover an ... | 2010 | 20665313 |
| salmonella enterica subsp. enterica in cattle egret (bubulcus ibis) chicks from central texas: prevalence, serotypes, pathogenicity, and epizootic potential. | cattle egrets have a worldwide distribution, feed in proximity to cattle and other domestic animals, and often nest in large colonies in urban woodlots. over a 3-yr period, nestlings from five cattle egret colonies from central texas, usa, were surveyed for salmonellosis. prevalence of infection ranged from 29% to 95%. seventeen salmonella enterica subsp. enterica serotypes were isolated, of which the 4,5,12:i-monophasic serotype predominated in cultures of both the digestive tract and pooled sp ... | 2010 | 20688631 |
| baylisascaris procyonis in raccoons in texas and its relationship to habitat characteristics. | raccoons (n=590) were collected from october 1999 to august 2003 from 35 counties across texas, usa, and gastrointestinal tracts were examined for baylisascaris procyonis. we documented b. procyonis in central and eastern texas. baylisascaris procyonis occurred in 5.4% raccoons in texas with an overall mean abundance and mean intensity of 0.4+/-0.1 and 7.4+/-2.3, respectively. prevalence was higher in central texas ecoregions and on clayey soil texture than other regions or soil textures of texa ... | 2010 | 20688690 |
| molecular basis of a linkage peak: exome sequencing and family-based analysis identify a rare genetic variant in the adipoq gene in the iras family study. | family-based linkage analysis has been a powerful tool for identification of genes contributing to traits with monogenic patterns of inheritance. these approaches have been of limited utility in identification of genes underlying complex traits. in contrast, searches for common genetic variants associated with complex traits have been highly successful. it is now widely recognized that common variations frequently explain only part of the inter-individual variation in populations. 'rare' genetic ... | 2010 | 20688759 |
| human coinfection with bartonella henselae and two hemotropic mycoplasma variants resembling mycoplasma ovis. | two variants of an organism resembling the ovine hemoplasma, mycoplasma ovis, were detected by pcr in blood samples from a veterinarian in texas. coinfection with similar variants has been described in sheep. this represents the first report of human infection with this organism. the veterinarian was coinfected with bartonella henselae. | 2010 | 20702675 |
| urban middle school parent perspectives: the vaccines they are willing to have their children receive using school-based immunization programs. | with new vaccination recommendations for adolescents, school-based immunization programs become a valuable alternative site for immunization. this study seeks to determine factors associated with parental willingness to utilize school-based programs for immunizations. | 2010 | 20708563 |
| prevalence of g6pd deficiency in a large cohort of hiv-infected patients. | glucose-6-phosphate dehydrogenase (g6pd) deficiency is the most common human enzyme defect. screening for this condition in hiv-infected patients from susceptible ethnic groups is recommended based on expert opinion. here we determined the prevalence of g6pd deficiency and the occurrence of g6pd-related hemolytic events in a large cohort of patients. | 2010 | 20732351 |
| differences in history of sexual behavior between patients with oropharyngeal squamous cell carcinoma and patients with squamous cell carcinoma at other head and neck sites. | background.: an emerging epidemic of human papillomavirus (hpv)-associated oropharyngeal cancer has been proposed. the purpose of this study was for us to compare the sexual behaviors of patients with squamous cell carcinoma of the oropharynx (sccop) and patients with squamous cell carcinoma of non-oropharyngeal (sccnop) head and neck sites to expand our understanding of sexual behavior as a risk factor for hpv-associated head and neck cancer. methods.: the sexual history of 165 patients with sc ... | 2011 | 20737488 |
| weekly monitoring of the water fluoride content in a fluoridated metropolitan city--results after 1 year. | it continues to be the goal of the united states department of health and human services to fluoridate community water supplies to prevent dental caries. in houston, texas, where community water is assumed to contain in the range of 0.7-1.2 ppm fluoride, water samples were taken from the same source on approximately a weekly basis over a period of 52 weeks. the purpose of this study was to determine the extent of fluctuation of water fluoride concentration in these samples. water fluoride analys ... | 2010 | 20737987 |
| postmortem findings in eight cases of influenza a/h1n1. | in march and early april 2009, cases of a new swine-origin influenza a (h1n1) virus were diagnosed in mexico and the united states. influenza virus presents as a respiratory infection with high morbidity and mortality. we describe the postmortem findings of eight confirmed cases of influenza a/h1n1 in a medical examiner setting. the eight cases falling under the jurisdiction of the harris county medical examiner (houston, tx, usa) with confirmed influenza a/h1n1 infection between june and septem ... | 2010 | 20802471 |
| utilizing spatiotemporal analysis of influenza-like illness and rapid tests to focus swine-origin influenza virus intervention. | in the spring of 2009, a novel strain of h1n1 swine-origin influenza a virus (s-oiv) emerged in mexico and the united states, and soon after was declared a pandemic by the world health organization. this work examined the ability of real-time reports of influenza-like illness (ili) symptoms and rapid influenza diagnostic tests (ridts) to approximate the spatiotemporal distribution of pcr-confirmed s-oiv cases for the purposes of focusing local intervention efforts. cluster and age adjusted relat ... | 2010 | 20810301 |
| who and where are the children yet to enroll in medicaid and the children's health insurance program? | kathleen sebelius, secretary of health and human services, has issued a challenge to enroll the millions of uninsured children eligible for public insurance in medicaid or the children's health insurance program (chip). this paper provides estimates of the rates at which children in the various states participated in these programs in 2008 as well as the number who were eligible for them but uninsured. according to our coverage estimates, an estimated 7.3 million children were uninsured on an av ... | 2010 | 20817690 |
| response to h1n1 in a u.s.-mexico border community. | public health experts from a county health department and a school of public health collaborated to establish a simple, functional surveillance system to monitor swine-origin influenza virus as it crossed from mexico into a texas border community during the 2009 pandemic. the draft national and state preparedness plans were found to be cumbersome at the local level, so a simple, more practical real-time surveillance and response system was developed, in part by modifying these documents, and imm ... | 2010 | 20825334 |
| eight cases of feline cutaneous leishmaniasis in texas. | leishmaniasis is a zoonotic disease caused by intracellular leishmania protozoa that are transmitted by sandflies. the disease occurs in 3 forms: cutaneous, mucocutaneous, and visceral. cutaneous leishmaniasis has been reported in cats in europe and south america and in 1 cat from texas. leishmania mexicana is endemic in texas and has been reported to cause cutaneous lesions in humans. this article describes the pathology of 8 biopsy cases of feline cutaneous leishmaniasis presented to the texas ... | 2010 | 20826847 |
| phase i and pharmacokinetic study of 3'-c-ethynylcytidine (tas-106), an inhibitor of rna polymerase i, ii and iii,in patients with advanced solid malignancies. | background tas-106 is a novel nucleoside analog that inhibits rna polymerases i, ii and ii and has demonstrated robust antitumor activity in a wide range of models of human cancer in preclinical studies. this study was performed to principally evaluate the feasibility of administering tas-106 as a bolus intravenous (iv) infusion every 3 weeks. patients and methods patients with advanced solid malignancies were treated with escalating doses of tas-106 as a single bolus iv infusion every 3 weeks. ... | 2010 | 20839029 |
| rabies surveillance in the united states during 2009. | during 2009, 49 states and puerto rico reported 6,690 rabid animals and 4 human rabies cases to the cdc, representing a 2.2% decrease from the 6,841 rabid animals and 2 human cases reported in 2008. approximately 92% of reported rabid animals were wildlife. relative contributions by the major animal groups were as follows: 2,327 (34.8%) raccoons, 1,625 (24.3%) bats, 1,603 (24.0%) skunks, 504 (75%) foxes, 300 (4.5%) cats, 81 (1.2%) dogs, and 74 (1.1%) cattle. compared with 2008, numbers of rabid ... | 2010 | 20839985 |
| addiction treatment outcomes, process and change: texas institute of behavioral research at texas christian university. | for more than 40 years the texas institute of behavioral research (ibr) has given special attention to assessment and evaluation of drug user populations, addiction treatment services and various cognitive and behavioral interventions. emphasis has been on studies in real-world settings and the use of multivariate methodologies to address evaluation issues within the context of longitudinal natural designs. historically, its program of addiction treatment research may be divided into three seque ... | 2010 | 20840168 |
| a study of the human decomposition sequence in central texas. | decomposition studies utilizing nonhuman subjects as human analogues are well established, but fewer studies utilizing intact human remains exist. this study provides data from a controlled decomposition study involving human remains in central texas. a 63.5-kg unmodified cadaver was placed in an open-air site and observed over a 10-week period from april 11 through june 19, 2008. a wire enclosure restricted scavenger access. state of decomposition and environmental conditions were recorded dail ... | 2011 | 20840291 |
| differences between the normal vaginal bacterial community of baboons and that of humans. | humans and baboons (papio spp.) share considerable anatomical and physiological similarities in their reproductive tracts. given the similarities, it is reasonable to expect that the normal vaginal microbial composition (microbiota) of baboons would be similar to that of humans. we have used a 16s rrna phylogenetic approach to assess the composition of the baboon vaginal microbiota in a set of nine animals from a captive facility and six from the wild. results show that although gram-positive ba ... | 2011 | 20853395 |
| phase ii study of dasatinib in patients with advanced non-small-cell lung cancer. | src family kinases (sfks) promote cancer progression and are commonly expressed in non-small-cell lung cancer (nsclc), but the clinical effects of sfk inhibition in nsclc are unknown. we conducted a phase ii trial of the sfk inhibitor dasatinib for advanced nsclc. we tested the hypotheses that the activation of epidermal growth factor receptor (egfr) or sfk or modulation of serum cytokines may predict a response to dasatinib. | 2010 | 20855820 |
| aflatoxin and pah exposure biomarkers in a u.s. population with a high incidence of hepatocellular carcinoma. | the incidence of hepatocellular carcinoma (hcc) is significantly elevated in a hispanic community in bexar county, texas. chronic exposure to dietary aflatoxins (afs) is a major risk factor for hcc; increased risk has been linked to polycyclic aromatic hydrocarbon (pah) co-exposure and hepatitis virus infection. the aims of this study were to assess af and pah exposures, investigate dietary factors that may contribute to increased af exposure, and determine the prevalence of hepatitis virus infe ... | 2010 | 20870273 |
| human cytokine response to texas crotaline envenomation before and after antivenom administration. | the aim of this study was to characterize the human cytokine response to texas crotaline envenomation before and after antivenom administration. | 2010 | 20887908 |
| accelerated hepatitis b vaccination schedule among drug users: a randomized controlled trial. | hepatitis b vaccine provides a model for improving uptake and completion of multidose vaccinations in the drug-using community. | 2010 | 20936979 |
| preparing underemployed latino u.s. nurses through the mexico nclex-rn success program. | the critical nursing shortage in u.s. communities along the united states-mexico border is compounded by the need for nurses who are linguistically and culturally concordant with the growing number of latinos in these communities. the innovative 16-week mexico nclex-rn success program responds to this need by helping underemployed latino nurses, who were educated in mexico and live in the united states, adapt linguistically and culturally to multiple-choice testing. ten of the program students h ... | 2010 | 20954572 |
| chagas disease risk in texas. | chagas disease, caused by trypanosoma cruzi, remains a serious public health concern in many areas of latin america, including méxico. it is also endemic in texas with an autochthonous canine cycle, abundant vectors (triatoma species) in many counties, and established domestic and peridomestic cycles which make competent reservoirs available throughout the state. yet, chagas disease is not reportable in texas, blood donor screening is not mandatory, and the serological profiles of human and cani ... | 2010 | 20957148 |
| critical assessment of preoperative urinary prostate cancer antigen 3 on the accuracy of prostate cancer staging. | knowledge about the staging significance of the prostate cancer antigen 3 (pca3) score to better identify pathologic features after radical prostatectomy (rp) is limited and controversial. | 2010 | 20980098 |
| direct and indirect effectiveness of influenza vaccination delivered to children at school preceding an epidemic caused by 3 new influenza virus variants. | influenza is an uncontrolled epidemic disease that is vaccine preventable. new recommendations for universal immunization present a challenge to the implementation of vaccine delivery. this field trial examines the effectiveness of school-based clinics for vaccine delivery before an epidemic caused by 3 new influenza virus variants not contained in the vaccine. | 2010 | 21028955 |
| use of interactive voice response technology by poison centers during the h1n1 outbreak. | interactive voice response (ivr) technology may facilitate poison centers to handle increased call volumes that may occur during public health emergencies. on 28 april 2009, the texas poison center network (tpcn) added a h1n1 message in english and spanish to its ivr system. this study tested whether ivr technology could be used to assist texas poison centers during the h1n1 outbreak. | 2010 | 21053187 |
| editorial comments-use of interactive voice response technology by poison centers during the h1n1 outbreak. | | 2010 | 21053188 |
| employment. man failed to show severe emotional distress from hiv rumor. | | 2010 | 21053401 |
| phylogeography of the spring and fall waves of the h1n1/09 pandemic influenza virus in the united states. | spatial variation in the epidemiological patterns of successive waves of pandemic influenza virus in humans has been documented throughout the 20th century but never understood at a molecular level. however, the unprecedented intensity of sampling and whole-genome sequencing of the h1n1/09 pandemic virus now makes such an approach possible. to determine whether the spring and fall waves of the h1n1/09 influenza pandemic were associated with different epidemiological patterns, we undertook a larg ... | 2010 | 21068250 |
| high rates of transitions to injecting drug use among mexican american non-injecting heroin users in san antonio, texas (never and former injectors). | to assess the incidence and rate of transition to injecting among mexican american noninjecting heroin users. | 2010 | 21075561 |
| an evolutionary framework for association testing in resequencing studies. | sequencing technologies are becoming cheap enough to apply to large numbers of study participants and promise to provide new insights into human phenotypes by bringing to light rare and previously unknown genetic variants. we develop a new framework for the analysis of sequence data that incorporates all of the major features of previously proposed approaches, including those focused on allele counts and allele burden, but is both more general and more powerful. we harness population genetic the ... | 2010 | 21085648 |
| molecular clustering based on erĪ± and eig121 predicts survival in high-grade serous carcinoma of the ovary/peritoneum. | assessment of estrogen receptor (er) expression by immunohistochemistry has yielded inconsistent results as a prognostic indicator in ovarian carcinoma. in breast and endometrial carcinomas, panels of estrogen-induced genes have shown improved prognostic capability over the use of er immunohistochemistry alone. for both breast and endometrial cancers, overexpression of estrogen-induced genes is associated with better prognosis. we hypothesized that analysis of a panel of estrogen-induced genes c ... | 2010 | 21102415 |
| de novo acute myeloid leukemia with inv(3)(q21q26.2) or t(3;3)(q21;q26.2): a clinicopathologic and cytogenetic study of an entity recently added to the who classification. | acute myeloid leukemia with inv(3)(q21q26.2) or t(3;3)(q21;q26.2) is a rare type of leukemia recently added to the world health organization (who) classification scheme. in this study, we analyzed the clinicopathologic and cytogenetic features of 30 cases of de novo acute myeloid leukemia with inv(3)/t(3;3). the median patient age was 53 years (range, 27-77 years). the platelet count was variable (range, 21-597 × 10(9)/l, median: 128 × 10(9)/l), and two (6.7%) patients presented with thrombocyto ... | 2010 | 21113141 |
| the genetic basis of spondyloarthritis: spartan/igas 2009. | a joint meeting was held in july 2009 in houston, texas, of members of the spondyloarthritis research and therapy network (spartan), founded in 2003 to promote research, education, and treatment of ankylosing spondylitis (as) and related forms of spondyloarthritis (spa), and members of international genetics of as (igas), founded in 2003 to encourage and coordinate studies internationally in the genetics of as. the general topic was the genetic basis of spa, with presentations on the future of h ... | 2010 | 21123336 |
| gender and wavefront higher order aberrations: do the genders see the world differently? | wavefront sensing technology has emerged as a means to advance our understanding of high-order aberrations of the human eye. | 2009 | 21140998 |
| distribution, prevalence, and genetic characterization of baylisascaris procyonis in selected areas of georgia. | baylisascaris procyonis is an intestinal nematode of raccoons (procyon lotor) that can cause fatal larval migrans in numerous species of birds and mammals, including humans. although this parasite has historically been absent in the southeastern united states, it has been found in isolated regions in the appalachian mountains and was recently documented in dekalb county, georgia. the first objective of the current study was to investigate the distribution and prevalence of b. procyonis in select ... | 2010 | 21158622 |
| anthropometric measures, presence of metabolic syndrome, and adherence to physical activity guidelines among african american church members, dallas, texas, 2008. | the low prevalence of physical activity among african americans and high risk of cardiovascular disease lends urgency to assessing the association between metabolic syndrome, abdominal obesity, and adherence to current physical activity guidelines. few studies have examined this association among african american adults. | 2010 | 21159230 |
| flt3 and npm1 mutations in myelodysplastic syndromes: frequency and potential value for predicting progression to acute myeloid leukemia. | we reviewed flt3 and npm1 mutation data in a large cohort of patients with myelodysplastic syndrome (mds). the frequencies of flt3 and npm1 mutation were 2.0% and 4.4%, respectively, and mutations were restricted to cases of intermediate- and high-risk mds. cytogenetic abnormalities were identified in 46.9% of cases. flt3 mutations were associated with a complex karyotype (p = .009), whereas npm1 mutations were associated with a diploid karyotype (p < .001). flt3 mutation (p < .001) was associat ... | 2011 | 21173125 |
| variation in physiological stress between bridge- and cave-roosting brazilian free-tailed bats. | since the late 1980s, brazilian free-tailed bats (tadarida brasiliensis) have increasingly used bridges as roosts in the southern united states. we examined differences in blood cortisol levels, body condition, and parasite load, as measures of physiological stress in bats roosting in bridges and bats roosting in caves. we collected data during three periods, coinciding with female phases of reproduction. for all measures, bats were captured during the nightly emergence from the roost and immedi ... | 2010 | 21175827 |
| neurocysticercosis in houston, texas: an update. | neurocysticercosis, one of the most common parasitic infections of the human nervous system, has emerged as an important infection in the united states. neurocysticercosis causes significant morbidity associated with acute seizures, chronic epilepsy, and hydrocephalus.we retrospectively identified patients with definitive or probable neurocysticercosis seen at ben taub general hospital, the largest public teaching hospital in houston, texas, from september 1997 through december 2005. we collecte ... | 2011 | 21200189 |
| human papillomavirus & who type i nasopharyngeal carcinoma. | nasopharyngeal carcinoma (npc) is a rare cancer in the u.s. that has a well-established association with epstein-barr virus(ebv) for who types ii/iii but less so for who type i. given the rise in oropharyngeal tumors positive for high risk human papillomavirus (hpv) and the unique biology of who type inpc, we chose to examine the relationship between hpv and who type i npc. | 2010 | 21225783 |
| rgs6 variants are associated with dietary fat intake in hispanics: the iras family study. | recently, a genome-wide association scan was completed in the iras (insulin resistance atherosclerosis study) family study (irasfs) hispanic-american cohort. multiple single-nucleotide polymorphisms (snps) in the g-protein signaling 6 (rgs6) gene were found to be associated with adiposity phenotypes. rgs6 has shown downstream antagonistic interplay with opioid receptors, targets of fatty/sugary food agonists. the possibility that rgs6 promotes tolerance and tachyphylaxis among the opioid recepto ... | 2011 | 21233807 |
| association of a novel functional promoter variant (rs2075533 c>t) in the apoptosis gene tnfsf8 with risk of lung cancer--a finding from texas lung cancer genome-wide association study. | published genome-wide association studies (gwass) have identified few variants in the known biological pathways involved in lung cancer etiology. to mine the possibly hidden causal single nucleotide polymorphisms (snps), we explored all snps in the extrinsic apoptosis pathway from our published gwas dataset for 1154 lung cancer cases and 1137 cancer-free controls. in an initial association analysis of 611 tagsnps in 41 apoptosis-related genes, we identified only 10 tagsnps associated with lung c ... | 2011 | 21292647 |
| an analysis of single nucleotide polymorphisms of 125 dna repair genes in the texas genome-wide association study of lung cancer with a replication for the xrcc4 snps. | dna repair genes are important for maintaining genomic stability and limiting carcinogenesis. we analyzed all single nucleotide polymorphisms (snps) of 125 dna repair genes covered by the illumina humanhap300 (v1.1) beadchips in a previously conducted genome-wide association study (gwas) of 1154 lung cancer cases and 1137 controls and replicated the top-hits of xrcc4 snps in an independent set of 597 cases and 611 controls in texas populations. we found that six of 20 xrcc4 snps were associated ... | 2011 | 21296624 |
| efficacy of european starling control to reduce salmonella enterica contamination in a concentrated animal feeding operation in the texas panhandle. | european starlings (sturnus vulgaris) are an invasive bird species known to cause damage to plant and animal agriculture. new evidence suggests starlings may also contribute to the maintenance and spread of diseases within livestock facilities. identifying and mitigating the risk pathways that contribute to disease in livestock is necessary to reduce production losses and contamination of human food products. to better understand the impact starlings have on disease transmission to cattle we ass ... | 2011 | 21324202 |
| congenital anomalies in the baboon (papio spp.). | background a comprehensive survey of the prevalence of congenital anomalies in baboons has not been previously reported. we report the congenital anomalies observed over a 26-year period in a large captive baboon colony. methods a computer search was performed for all baboon congenital anomalies identified at necropsy and recorded on necropsy submissions. results we identified 198 congenital anomalies in 166 baboons from 9972 necropsies (1.66% of total necropsies). the nervous, urogenital, mu ... | 2011 | 21332757 |
| virus detection and duration of illness among patients with 2009 pandemic influenza a (h1n1) virus infection in texas. | knowledge from early outbreaks is limited regarding the virus detection and illness duration of the 2009 pandemic influenza a (h1n1) infections. during the period from april to may 2009 in texas, we collected serial nasopharyngeal (np) and stool specimens from 35 participants, testing by real-time reverse transcriptase-polymerase chain reaction (rrt-pcr) and culture. the participants were aged 2 months to 71 years; 25 (71%) were under 18. the median duration of measured fever was 3.0 days and of ... | 2011 | 21342881 |
| diagnosis of 2009 pandemic influenza a (ph1n1) and seasonal influenza using rapid influenza antigen tests, san antonio, texas, april-june 2009. | clinicians frequently use influenza rapid antigen tests for diagnostic testing. we tested nasal wash samples from 1 april to 7 june 2009 from 1538 patients using the quickvue influenza a+b (quidel) rapid influenza antigen test and compared the results with real-time reverse transcription polymerase chain reaction (rrt-pcr) assay (gold standard). the prevalence of 2009 pandemic influenza a (ph1n1) was 1.98%, seasonal influenza type a .87%, and seasonal influenza type b 2.07%. the sensitivity and ... | 2011 | 21342882 |
| household transmission of 2009 pandemic influenza a (h1n1) and nonpharmaceutical interventions among households of high school students in san antonio, texas. | san antonio, texas, was one of the first metropolitan areas where 2009 pandemic influenza a (h1n1) virus (ph1n1) was detected. identification of laboratory-confirmed ph1n1 in 2 students led to a preemptive 8-day closure of their high school. we assessed transmission of ph1n1 and changes in adoption of nonpharmaceutical interventions (npis) within households of students attending the affected school. household secondary attack rates were 3.7% overall and 9.1% among those 0-4 years of age. widespr ... | 2011 | 21342887 |
| using sentinel surveillance system to monitor seasonal and novel h1n1 influenza infection in houston, texas: outcome analysis of 2008-2009 flu season. | the advent of the novel h1n1 virus prompted the houston department of health and human services (hdhhs) to use the existing sentinel surveillance system to effectively monitor the situation of novel h1n1 virus in the houston metropolitan area. the objective of this study was to evaluate the demographic characteristics and common symptoms associated with confirmed cases of seasonal influenza and novel h1n1 virus reported to hdhhs between october 2008 and october 2009. a total of 30 providers were ... | 2011 | 21380790 |