Publications

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evaluation of parasiticidal activity of fenbendazole, ivermectin, oxibendazole, and pyrantel pamoate in horse foals with emphasis on ascarids (parascaris equorum) in field studies on five farms in central kentucky in 2007.horse foals on five farms in central kentucky were used in field studies in 2007 evaluating activity of paste formulations of four compounds (fenbendazole-fbz, ivermectin-ivm, oxibendazole-obz, and pyrantel pamoate-prt) against internal parasites with emphasis on ascarids (parascaris equorum). it has been well established the last few years that there is widespread resistance of p. equorum to ivermectin. the main purpose of the present research was to obtain current data on ascaridicidal activit ...200818470536
probable reason why small strongyle epg counts are returning "early" after ivermectin treatment of horses on a farm in central kentucky.critical tests were carried out in 2008 in four yearling horses (h-2, h-4, h-10, and h-11) born and raised together on a farm (mc) in central kentucky. these horses were treated intraorally with ivermectin paste at the dose rate of 200 microg/kg. the main interest was to try and determine more precisely, from posttreatment (pt) worm count data, the current activity of ivermectin against small strongyles in a horse herd. these horses had been treated repeatedly with this compound and counts of sm ...200918931857
the influence of use-related, environmental, and managerial factors on soil loss from recreational trails.recreational uses of unsurfaced trails inevitably result in their degradation, with the type and extent of resource impact influenced by factors such as soil texture, topography, climate, trail design and maintenance, and type and amount of use. of particular concern, the loss of soil through erosion is generally considered a significant and irreversible form of trail impact. this research investigated the influence of several use-related, environmental, and managerial factors on soil loss on re ...200919062152
application of an automated surveillance-data-analysis system in a laboratory-based early-warning system for detection of an abortion outbreak in mares.to develop an early-warning automated surveillance-data-analysis system for early outbreak detection and reporting and to assess its performance on an abortion outbreak in mares in kentucky.200919231958
environmental salmonella surveillance in the ohio state university veterinary teaching hospital.sampling was conducted at the ohio state university's veterinary teaching hospital (osu-vth) to evaluate the extent of environmental contamination with salmonella enterica, at 1-week intervals beginning march 19, 2007, through may 21, 2007. environmental samples were collected from various surface and floor locations in the equine and food animal areas using sterile moistened gauze sponges. all samples were processed using standard bacteriologic culture to identify the presence of salmonella spp ...200919272003
nonsteroidal anti-inflammatory agents and musculoskeletal injuries in thoroughbred racehorses in kentucky.injuries sustained by horses during racing have been considered as an unavoidable part of horse racing. many factors may be associated with the musculoskeletal injuries of thoroughbred race horses. this study surveyed the amounts of nonsteroidal anti-inflammatory agents (nsaids) in injured horse's biological system (plasma) at kentucky racetracks from january 1, 1995 through december 31, 1996. during that period, there were 84 catastrophic cases (euthanized horses) and 126 noncatastrophic cases. ...200919646092
prevalence of various presale radiographic findings and association of findings with sales price in thoroughbred yearlings sold in kentucky.to estimate prevalences of various presale radiographic findings and of presale arthroscopy in horses offered for sale at the 2006 keeneland september yearling sale and to compare sales prices between yearlings with and without various presale radiographic findings or a history of arthroscopy.201020151870
initial occurrence of taylorella asinigenitalis and its detection in nurse mares, a stallion and donkeys in kentucky.in 1998, a newly identified bacterium taylorella asinigenitalis was isolated from the external genitalia and reproductive tracts of nurse mares, a stallion and donkey jacks in kentucky. an extensive regulatory effort was implemented to contain the outbreak including the tracing and testing of 232 horses and donkeys on 58 premises. t. asinigenitalis was isolated from the reproductive tract of 10 adult equids, including two donkey jacks, one paint quarter-horse stallion and seven draft-type breedi ...201020537742
critical tests evaluating efficacy of moxidectin against small strongyles in horses from a herd for which reduced activity had been found in field tests in central kentucky.critical tests were performed in 2009 and 2010 in four 2-year-old horses naturally infected with internal parasites. the horses were from a herd (farm mc) where reduced activity of ivermectin and moxidectin on small strongyles was demonstrated previously from epg (eggs/gram of feces) data in field tests. also, in critical tests in horses from the same herd, ivermectin was less effective on immature small strongyles in the lumen of the large intestine than when the drug was first marketed. the ma ...201020714749
analysis of multiyear studies in horses in kentucky to ascertain whether counts of eggs and larvae per gram of feces are reliable indicators of numbers of strongyles and ascarids present.increasing levels of anthelmintic resistance in equine nematodes have led to recommendations of more sustainable anthelmintic treatment protocols with emphasis on parasite surveillance and diagnosis, rather than prophylactic calendar-based treatments. this requires knowledge of the diagnostic test performance of techniques for counts of eggs per gram of feces (epg) as well as methods for culturing, counting and identifying third stage (l(3)) strongyle larvae per gram of feces (lpg). for horses, ...201020850927
field tests demonstrating reduced activity of ivermectin and moxidectin against small strongyles in horses on 14 farms in central kentucky in 2007-2009.efficacy of ivermectin (ivm) and moxidectin (mox) against small strongyles was evaluated in horses (n=363) in field tests on 14 farms in central kentucky between 2007 and 2009. most of the horses were yearlings but a few were weanlings and mares. the number of horses treated with ivm was 255 and those treated with mox was 108. horses on six farms were allotted into two groups. one group was treated with each of the two drugs, whereas horses on the other eight farms were treated with only one of ...201120862493
horse species symposium: contagious equine metritis: an insidious threat to the horse breeding industry in the united states.contagious equine metritis (cem) has given rise to international concern since it was first recognized as a novel venereal disease of equids in 1977 and the etiologic agent was identified as a previously undescribed bacterium, taylorella equigenitalis. horse industry concerns over cem centered on the ease with which this bacterium could be disseminated, the significance of t. equigenitalis as a cause of short-term infertility in the mare, and the existence of the carrier state in the stallion an ...201020889687
infectivity of equine h3n8 influenza virus in bovine cells and calves.serological evidence for influenza a, subtype h1 and h3 virus infections of bovines, associated with respiratory disease and decreased milk production, has been reported. equine h3n8 influenza virus circulates widely and was responsible for the introduction of h3n8 influenza into canines.201020976994
three recently recognized species of cyathostomes (nematoda: strongylidae) in equids in kentucky.three species of cyathostomes--cylicocyclus ashworthi, cylicostephanus bidentatus, and cylicostephanus hybridus were identified recently in horses in kentucky. general characteristics and distinguishing description of these species are presented. distribution of these species and their role in the horse strongylid community are discussed. the importance of examining the entire contents of the large intestine or alternatively a high number of specimens in order to recover and identify species res ...201021107866
reduced activity of moxidectin and ivermectin on small strongyles in young horses on a farm (bc) in central kentucky in two field tests with notes on variable counts of eggs per gram of feces (epgs).two field tests (a and b) were conducted in thoroughbred weanlings born in 2008 and 2009 on a farm (bc) in central kentucky. the purpose was to determine the current efficacy of moxidectin (mox) and ivermectin (ivm) on small strongyles by pre- and posttreatment counts of eggs per gram of feces (epgs) in this geographical area. in previous parasite studies in horses on this farm and in horses on numerous other farms in this area, cultures of feces indicated the strongyle larvae were all small str ...201121212983
further evaluation in field tests of the activity of three anthelmintics (fenbendazole, oxibendazole, and pyrantel pamoate) against the ascarid parascaris equorum in horse foals on eight farms in central kentucky (2009-2010).the activity of three anthelmintics (fenbendazole-fbz; oxibendazole-obz; and pyrantel pamoate-prt) was ascertained against the ascarid parascaris equorum in horse foals on eight farms in central kentucky (2009-2010) in field tests. a total of 316 foals were treated, and 168 (53.2%) were passing ascarid eggs on the day of treatment. evaluation of drug efficacy was determined qualitatively by comparing the number of foals passing ascarid eggs in their feces before and after treatment. the main pur ...201121499750
diagnostic and epidemiologic analysis of the 2008-2010 investigation of a multi-year outbreak of contagious equine metritis in the united states.contagious equine metritis (cem) is a highly contagious venereal disease of horses caused by taylorella equigenitalis. during testing for semen export purposes, a stallion in kentucky was found to be t. equigenitalis culture positive in december of 2008. this finding triggered an extensive regulatory investigation to search for additional positive horses, determine the extent of the outbreak, identify the potential source of the outbreak, and ultimately return the united states to cem-free statu ...201121715032
evaluation of the field efficacy of an avirulent live lawsonia intracellularis vaccine in foals.equine proliferative enteropathy caused by lawsonia intracellularis is an emerging disease with as yet unaddressed preventative measures. the hypothesis of this study was that vaccination will prevent clinical and sub-clinical disease. weanling thoroughbreds (n=202) from central kentucky were randomly assigned into two groups (vaccinated and non-vaccinated). vaccinated foals received 30ml of an avirulent, live l. intracellularis vaccine intra-rectally twice, 30days apart. foals were monitored fo ...201121741284
Adaptation and validation of a bacteria-specific enzyme-linked immunosorbent assay for determination of farm-specific Lawsonia intracellularis seroprevalence in central Kentucky Thoroughbreds.Lawsonia intracellularis is the causative agent of equine proliferative enteropathy (EPE), a disease for which no large-scale seroprevalence studies have been conducted. Objectives: To validate and use an equine-specific enzyme-linked immunosorbent assay (ELISA) for L. intracellularis to determine the seroprevalence of L. intracellularis on numerous farms.201122082442
investigation of strongyle epg values in horse mares relative to known age, number positive, and level of egg shedding in field studies on 26 farms in central kentucky (2010-2011).a parasite study was done in 1,300 horse mares on 26 farms in central kentucky over a 5-month period in 2010 and 2011. the mares included 1,114 thoroughbreds (tb) on 24 farms, 64 standardbreds (sb) on 1 farm, and 122 mixed light horse types (mlh) on 1 farm. the objective of this research was to determine strongyle eggs per gram of feces (epg) counts for evaluation by known age, number positive, and level of egg shedding by the mares. this was done to establish strongyle epg profiles for the mare ...201122167377
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