Publications

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knowledge about hepatitis c virus infection and acceptability of testing in the 1945-1965 birth cohort (baby boomers) presenting to a large urban emergency department: a pilot study.hepatitis c virus (hcv) is responsible for the most common chronic bloodborne infection in the united states. the centers for disease control (cdc) recently recommended screening all patients born between 1945-1965 (baby boomers) at least once for hcv infection. new york state has since mandated screening of baby boomers for hcv in nearly all patient care settings and encouraged it in the emergency department (ed).201626954104
a systematic model improves hepatitis c virus birth cohort screening in hospital-based primary care.despite national and local governing board recommendations in the united states of america to perform an hcv screening test in baby boomers, screening rates remain low. our goal was to study the impact of an hcv screening and link-to-care programme with patient navigation in two new york city primary care practices. this was a 2-year prospective study of patients born between 1945-1965 ("baby boomers") with encounters at two primary care practices at the mount sinai hospital between november 1, ...201628039935
correlates of hepatitis c virus infection in the targeted testing program of the new york city jail system.the objective of this study was to understand predictors of hepatitis c virus (hcv) antibody positivity in a large urban jail system in new york city.201728005477
hepatitis c seroprevalence among hiv-infected childbearing women in new york state in 2006.to identify factors associated with maternal hepatitis c virus (hcv) seroprevalence and transmission of hcv as identified by qualitative hcv ribonucleic acid (rna) in the infants of human immunodeficiency virus (hiv) infected women delivering in new york state (nys) in 2006.201626520159
hepatitis c virus infection in the 1945-1965 birth cohort (baby boomers) in a large urban ed.the us preventive services task force recommends one-time screening of the 1945-1965 birth cohort (baby boomers) for hepatitis c (hcv) infection. new york state legislation mandates screening of baby boomers for hcv in most patient care settings except the emergency department (ed). this cross-sectional study explores baby boomer knowledge of hcv, prevalence of hcv infection, and linkage to care from a large urban ed.201626809931
opioid use trajectories, injection drug use, and hepatitis c virus risk among young adult immigrants from the former soviet union living in new york city.available evidence suggests that young former soviet union immigrants in new york city have high rates of non-medical prescription opioid and heroin use, drug injection and injection-related risk behavior, making them vulnerable to hepatitis c virus (hcv)/human immunodeficiency virus (hiv) infection, overdose and associated harms. this group has been the focus of little research, however. this paper presents quantitative and qualitative data from 80 former soviet immigrants (ages 18-29) to chara ...201526132715
incidence and prevalence of hepatitis c virus infection among persons who inject drugs in new york city: 2006-2013.hepatitis c virus infection is a source of significant preventable morbidity and mortality among persons who inject drugs (pwid). we sought to assess trends in hepatitis c virus (hcv) infection among pwid from 2006 to 2013 in new york city (nyc).201525891230
taking care of themselves: how long-term injection drug users remain hiv and hepatitis c free.though prevalence of hiv and especially hepatitis c is high among people who inject drugs (pwid) in new york, about a third of those who have injected for 8-15 years have avoided infection by either virus despite their long-term drug use. based on life history interviews with 35 long-term pwid in new york, this article seeks to show how successful integration and performance of various drug using and non-drug using roles may have contributed to some of these pwid's staying uninfected with either ...201525688570
neighborhood inequalities in hepatitis c mortality: spatial and temporal patterns and associated factors.deaths attributable to hepatitis c (hcv) infection are increasing in the usa even as highly effective treatments become available. neighborhood-level inequalities create barriers to care and treatment for many vulnerable populations. we seek to characterize citywide trends in hcv mortality rates over time and identify and describe neighborhoods in new york city (nyc) with disproportionately high rates and associated factors. we used a multiple cause of death (mcod) definition for hcv mortality. ...201728623451
trends in hiv and hcv risk behaviors and prevalent infection among people who inject drugs in new york city, 2005-2012.we assess trends in hiv and hepatitis c virus (hcv) risk behaviors and prevalent infection among people who inject drugs (pwid) in new york city (nyc).201728604434
substance abuse treatment utilization, hiv risk behaviors, and recruitment among suburban injection drug users in long island, new york.prevention and treatment of injection drug use remains a public health concern. we used data from the 2005 centers for disease control and prevention national hiv behavioral surveillance system to assess substance abuse treatment utilization, risk behaviors, and recruitment processes in a respondent driven sample of suburban injectors. twelve service utilization and injection risk variables were analyzed using latent class analysis. three latent classes were identified: low use, low risk; low us ...201423709253
hepatitis c screening beyond cdc guidelines in an egyptian immigrant community.many egyptian-born persons in the u.s. are at high risk of chronic hepatitis c virus (hcv) infection, yet are not aware of their infection and lack healthcare coverage or linkage to care. in this study, we target egyptian-born persons living in the new york city area for screening and link to care.201423890188
estimating the prevalence of hepatitis c infection in new york city using surveillance data.hepatitis c virus is the most common chronic blood-borne infection in the usa. based on results of a serosurvey, national prevalence is estimated to be 1·3% or 3·2 million people. sub-national estimates are not available for most jurisdictions. hepatitis c surveillance data was adjusted for death, out-migration, under-diagnosis, and undetectable blood rna, to estimate prevalence in new york city (nyc). the prevalence of hepatitis c infection in adults aged ⩾20 years in nyc is 2·37% (range 1·53-4 ...201423657093
advances in the treatment of hepatitis c virus infection.since 2007, the annual age-adjusted mortality rate in hepatitis c virus (hcv) infection in the united states has been greater than that in hiv disease, reflecting the continuing decline in hiv-related mortality and the continuing increase in hcv-related mortality. the approval of 2 new direct-acting antivirals within the past year, as well as the promise offered by numerous other direct-acting agents in development, provides hope that we will be able to markedly improve our ability to cure hcv d ...201422538244
managing adverse effects and complications in completing treatment for hepatitis c virus infection.the addition of direct-acting antivirals (daas) to hepatitis c virus (hcv) treatment regimens has made treatment more effective and patient management more complex. shepherding patients through a full course of hcv therapy requires motivation and involvement on the part of the patient and the physician. indeed, physician inexperience and lack of confidence in guiding patients through the challenges of treatment appears to be a primary reason for early discontinuation of therapy. among the many c ...201223154251
hepatitis c transmission due to contamination of multidose medication vials: summary of an outbreak and a call to action.in may 2001, the new york city department of health and mental hygiene was informed of a cluster of 4 patients treated at an outpatient gastroenterology center who developed acute hepatitis c virus infection. an investigation identified a total of 12 clinic-associated hepatitis c virus transmissions and the outbreak and was traced to unsafe handling of multidose anesthetic vials and possible re-use of contaminated needles. this report typifies the types of outbreaks that continue to occur despit ...201322632822
risk of hip fracture associated with hepatitis c virus infection and hepatitis c/human immunodeficiency virus coinfection.hepatitis c virus (hcv) infection has been associated with reduced bone mineral density, but its association with fracture rates is unknown, particularly in the setting of human immunodeficiency virus (hiv) coinfection. our aims were to determine whether persons with hcv infection alone are at increased risk for hip fracture, compared to uninfected individuals, and to examine whether the risk of hip fracture is higher among hcv/hiv-coinfected persons, compared to those with hcv alone, those with ...201222619086
geographic epidemiology of hepatocellular carcinoma, viral hepatitis, and socioeconomic position in new york city.liver cancer (hepatocellular carcinoma (hcc)) incidence and mortality rates are increasing in the united states. new york city (nyc) has a high burden of liver cancer risk factors, including hepatitis c (hcv) and hepatitis b (hbv) infection, which disproportionately affect persons of low socioeconomic position. identifying neighborhoods with hcc disparities is essential to effectively define targeted cancer control strategies.201728573469
risk factors for hepatitis c seropositivity among young people who inject drugs in new york city: implications for prevention.hepatitis c virus (hcv) infection remains a significant problem in the united states, with people who inject drugs (pwid) disproportionately afflicted. over the last decade rates of heroin use have more than doubled, with young persons (18-25 years) demonstrating the largest increase.201728542351
disparities in reportable communicable disease incidence by census tract-level poverty, new york city, 2006-2013.we described disparities in selected communicable disease incidence across area-based poverty levels in new york city, an area with more than 8 million residents and pronounced household income inequality.201526180961
barriers to treatment among new york city residents with chronic hepatitis c virus infection, 2014.new, highly effective hepatitis c virus (hcv) medications recently changed the landscape of hcv treatment. access to treatment, however, is limited. the new york city department of health and mental hygiene conducted an enhanced surveillance project to better understand the reasons patients are not treated for hcv.201727252563
risk factors for hcv infection among young adults in rural new york who inject prescription opioid analgesics.we investigated a cluster of new hepatitis c cases in rural new york among a cohort of young people who inject drugs (pwid) and misuse prescription opioid analgesics (poa).201425211717
a public health approach to hepatitis c in an urban setting.the clinical consequences of hcv infection are increasing because the population with the highest prevalence of the infection, persons born between 1945 and 1965, is aging. as a result, health care expenditures are expected to increase. now that a cure for hcv infection is the norm, a public health approach is necessary to identify, link to care, and treat infected persons and prevent new infections. we believe that the success of public health interventions, such as those for tuberculosis, can ...201728426310
prisoners treated for hepatitis c with protease inhibitor, new york, usa, 2012. 201525531029
the evolution of hiv testing requirements in new york state, 1989-2013.in 2010, new york state (nys) made major changes to its hiv testing law to come more closely into compliance with 2006 recommendations of the centers for disease control and prevention. because of the size and severity of the epidemic in nys, the strong public health response, and powerful advocacy community, the state had early on enacted strict rules around all aspects of hiv testing. between 2006 and 2010, 12 distinct legislative proposals were advanced to modernize nys's approach, leading ul ...201525545494
hepatitis c surveillance among youth and young adults in new york city, 2009-2013.increases in prescription opioid misuse, injection drug use, and hepatitis c infections have been reported among youth and young adults in the usa, particularly in rural and suburban areas. to better understand these trends in new york city and to characterize demographics and risk factors among a population who, by virtue of their age, are more likely to be recently infected with hepatitis c, we analyzed routine hepatitis c surveillance data from 2009 to 2013 and investigated a sample of person ...201525450518
matching hiv, tuberculosis, viral hepatitis, and sexually transmitted diseases surveillance data, 2000-2010: identification of infectious disease syndemics in new york city.in 2012, the new york city department of health and mental hygiene matched hiv, tuberculosis, viral hepatitis, and sexually transmitted disease surveillance data to identify the burden of infection with multiple diseases.201424335712
prescription drug misuse and risk behaviors among young injection drug users.prescription drug misuse among young adults, especially opioids, is a substantial public health problem in the united states. although risks associated with injection of illicit drugs are well established, injection and sexual risks associated with misuse of prescription drugs are under-studied. forty young injection drug users aged 16 to 25 who reported injection of a prescription drug were recruited in 2008-09 in los angeles and new york city. descriptive quantitative and qualitative data were ...201723908999
rapidly progressing hepatitis c in new york gay men. new surveillance networks needed. 200717569166
estimating the mortality rate of hepatitis c using multiple data sources.the new york state hospital discharge database and the multiple cause-of-death file were used to estimate the mortality rate of hepatitis c in new york state excluding new york city in 1997. the mortality rate with hepatitis c was severely underestimated when each data source was used alone. applying the capture recapture method using the hospital discharge database and the multiple cause-of-death file appears to be an efficient method to estimate the mortality rate with hepatitis c.200515724719
hepatitis c screening and management practices: a survey of drug treatment and syringe exchange programs in new york city. 200212144980
hepatitis c direct acting antiviral therapies in a new york city hiv/aids special needs plan: uptake and barriers. 201526669792
methadone medical maintenance (mmm): treating chronic opioid dependence in private medical practice--a summary report (1983-1998).methadone medical maintenance (mmm) was implemented in 1983 to enable socially rehabilitated methadone patients to be treated in the offices of private physicians rather than in the traditional clinic system. over a period of 15 years, 158 methadone patients who fulfilled specific criteria within the clinic system entered this program in new york city. participating patients reported to their physician once a month and received a one-month supply of methadone tablets rather than a one-day liquid ...201311064489
hepatitis c screening of the "birth cohort" (born 1945-1965) and younger inmates of new york city jails.to examine uptake of screening for all individuals born between 1945 and 1965 (referred to by the centers for disease control and prevention as the "birth cohort") and outline preliminary hcv prevalence data in the new york city jail system.201627196656
from long-term injecting to long-term non-injecting heroin and cocaine use: the persistence of changed drug habits.transitioning from injecting to non-injecting routes of drug administration can provide important individual and community health benefits. we assessed characteristics of persons who had ceased injecting while continuing to use heroin and/or cocaine in new york city.201627776677
factors associated with hepatitis c infection among hiv-infected men who have sex with men with no reported injection drug use in new york city, 2000-2010.hepatitis c (hcv) infection is a major source of morbidity and mortality among hiv-infected patients. despite decreasing hcv incidence in the united states, the proportion of cases among men who have sex with men (msm) without history of injection drug use (idu) in new york city has more than tripled between 2000 and 2010.201526222751
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