Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| neighborhood inequalities in hepatitis c mortality: spatial and temporal patterns and associated factors. | deaths attributable to hepatitis c (hcv) infection are increasing in the usa even as highly effective treatments become available. neighborhood-level inequalities create barriers to care and treatment for many vulnerable populations. we seek to characterize citywide trends in hcv mortality rates over time and identify and describe neighborhoods in new york city (nyc) with disproportionately high rates and associated factors. we used a multiple cause of death (mcod) definition for hcv mortality. ... | 2017 | 28623451 |
| trends in hiv and hcv risk behaviors and prevalent infection among people who inject drugs in new york city, 2005-2012. | we assess trends in hiv and hepatitis c virus (hcv) risk behaviors and prevalent infection among people who inject drugs (pwid) in new york city (nyc). | 2017 | 28604434 |
| geographic epidemiology of hepatocellular carcinoma, viral hepatitis, and socioeconomic position in new york city. | liver cancer (hepatocellular carcinoma (hcc)) incidence and mortality rates are increasing in the united states. new york city (nyc) has a high burden of liver cancer risk factors, including hepatitis c (hcv) and hepatitis b (hbv) infection, which disproportionately affect persons of low socioeconomic position. identifying neighborhoods with hcc disparities is essential to effectively define targeted cancer control strategies. | 2017 | 28573469 |
| risk factors for hepatitis c seropositivity among young people who inject drugs in new york city: implications for prevention. | hepatitis c virus (hcv) infection remains a significant problem in the united states, with people who inject drugs (pwid) disproportionately afflicted. over the last decade rates of heroin use have more than doubled, with young persons (18-25 years) demonstrating the largest increase. | 2017 | 28542351 |
| a public health approach to hepatitis c in an urban setting. | the clinical consequences of hcv infection are increasing because the population with the highest prevalence of the infection, persons born between 1945 and 1965, is aging. as a result, health care expenditures are expected to increase. now that a cure for hcv infection is the norm, a public health approach is necessary to identify, link to care, and treat infected persons and prevent new infections. we believe that the success of public health interventions, such as those for tuberculosis, can ... | 2017 | 28426310 |
| a systematic model improves hepatitis c virus birth cohort screening in hospital-based primary care. | despite national and local governing board recommendations in the united states of america to perform an hcv screening test in baby boomers, screening rates remain low. our goal was to study the impact of an hcv screening and link-to-care programme with patient navigation in two new york city primary care practices. this was a 2-year prospective study of patients born between 1945-1965 ("baby boomers") with encounters at two primary care practices at the mount sinai hospital between november 1, ... | 2016 | 28039935 |
| correlates of hepatitis c virus infection in the targeted testing program of the new york city jail system. | the objective of this study was to understand predictors of hepatitis c virus (hcv) antibody positivity in a large urban jail system in new york city. | 2017 | 28005477 |
| racial differences in hiv and hcv risk behaviors, transmission, and prevention knowledge among non-treatment-seeking individuals with opioid use disorder. | in light of new york's recently reinforced strategy to end the aids epidemic by expanding testing, treatment, and access to pre-exposure prophylaxis (prep), we assessed drug use and sexual risk behaviors, along with hiv/hepatitis c virus (hcv) transmission and prevention knowledge among non-treatment-seeking adults with opioid use disorder (oud) in new york city. over the course of 18 months, volunteers screening for research studies in the opioid laboratory at the new york state psychiatric ins ... | 2017 | 27918880 |
| from long-term injecting to long-term non-injecting heroin and cocaine use: the persistence of changed drug habits. | transitioning from injecting to non-injecting routes of drug administration can provide important individual and community health benefits. we assessed characteristics of persons who had ceased injecting while continuing to use heroin and/or cocaine in new york city. | 2016 | 27776677 |
| hepatocellular carcinoma and viral hepatitis in new york city. | the incidence and mortality rate of hepatocellular carcinoma (hcc) are increasing in the united states. viral hepatitis infection is a primary risk factor for hcc. this study describes the relationship between viral hepatitis and hcc in new york city (nyc). | 2016 | 27585801 |
| barriers to treatment among new york city residents with chronic hepatitis c virus infection, 2014. | new, highly effective hepatitis c virus (hcv) medications recently changed the landscape of hcv treatment. access to treatment, however, is limited. the new york city department of health and mental hygiene conducted an enhanced surveillance project to better understand the reasons patients are not treated for hcv. | 2017 | 27252563 |
| hepatitis c screening of the "birth cohort" (born 1945-1965) and younger inmates of new york city jails. | to examine uptake of screening for all individuals born between 1945 and 1965 (referred to by the centers for disease control and prevention as the "birth cohort") and outline preliminary hcv prevalence data in the new york city jail system. | 2016 | 27196656 |
| knowledge about hepatitis c virus infection and acceptability of testing in the 1945-1965 birth cohort (baby boomers) presenting to a large urban emergency department: a pilot study. | hepatitis c virus (hcv) is responsible for the most common chronic bloodborne infection in the united states. the centers for disease control (cdc) recently recommended screening all patients born between 1945-1965 (baby boomers) at least once for hcv infection. new york state has since mandated screening of baby boomers for hcv in nearly all patient care settings and encouraged it in the emergency department (ed). | 2016 | 26954104 |
| strengthening screening for hiv, hepatitis c, and stis: an innovative partnership between the health department and community health centers in new york city. | in new york city, federally qualified health centers (fqhcs) are ideal partners for health departments because of their location in neighborhoods with high rates of hiv, hepatitis c virus (hcv) infection, and gonorrhea. providers have experienced many barriers to following screening and treatment recommendations. in 2013, the new york city department of health and mental hygiene partnered with six fqhcs, representing 14 clinics, to make screening for hiv and hcv routine and increase adherence to ... | 2017 | 26862225 |
| hepatitis c virus infection in the 1945-1965 birth cohort (baby boomers) in a large urban ed. | the us preventive services task force recommends one-time screening of the 1945-1965 birth cohort (baby boomers) for hepatitis c (hcv) infection. new york state legislation mandates screening of baby boomers for hcv in most patient care settings except the emergency department (ed). this cross-sectional study explores baby boomer knowledge of hcv, prevalence of hcv infection, and linkage to care from a large urban ed. | 2016 | 26809931 |
| hepatitis c direct acting antiviral therapies in a new york city hiv/aids special needs plan: uptake and barriers. | 2015 | 26669792 | |
| hepatitis c seroprevalence among hiv-infected childbearing women in new york state in 2006. | to identify factors associated with maternal hepatitis c virus (hcv) seroprevalence and transmission of hcv as identified by qualitative hcv ribonucleic acid (rna) in the infants of human immunodeficiency virus (hiv) infected women delivering in new york state (nys) in 2006. | 2016 | 26520159 |
| factors associated with hepatitis c infection among hiv-infected men who have sex with men with no reported injection drug use in new york city, 2000-2010. | hepatitis c (hcv) infection is a major source of morbidity and mortality among hiv-infected patients. despite decreasing hcv incidence in the united states, the proportion of cases among men who have sex with men (msm) without history of injection drug use (idu) in new york city has more than tripled between 2000 and 2010. | 2015 | 26222751 |
| disparities in reportable communicable disease incidence by census tract-level poverty, new york city, 2006-2013. | we described disparities in selected communicable disease incidence across area-based poverty levels in new york city, an area with more than 8 million residents and pronounced household income inequality. | 2015 | 26180961 |
| opioid use trajectories, injection drug use, and hepatitis c virus risk among young adult immigrants from the former soviet union living in new york city. | available evidence suggests that young former soviet union immigrants in new york city have high rates of non-medical prescription opioid and heroin use, drug injection and injection-related risk behavior, making them vulnerable to hepatitis c virus (hcv)/human immunodeficiency virus (hiv) infection, overdose and associated harms. this group has been the focus of little research, however. this paper presents quantitative and qualitative data from 80 former soviet immigrants (ages 18-29) to chara ... | 2015 | 26132715 |
| incidence and prevalence of hepatitis c virus infection among persons who inject drugs in new york city: 2006-2013. | hepatitis c virus infection is a source of significant preventable morbidity and mortality among persons who inject drugs (pwid). we sought to assess trends in hepatitis c virus (hcv) infection among pwid from 2006 to 2013 in new york city (nyc). | 2015 | 25891230 |
| taking care of themselves: how long-term injection drug users remain hiv and hepatitis c free. | though prevalence of hiv and especially hepatitis c is high among people who inject drugs (pwid) in new york, about a third of those who have injected for 8-15 years have avoided infection by either virus despite their long-term drug use. based on life history interviews with 35 long-term pwid in new york, this article seeks to show how successful integration and performance of various drug using and non-drug using roles may have contributed to some of these pwid's staying uninfected with either ... | 2015 | 25688570 |
| the evolution of hiv testing requirements in new york state, 1989-2013. | in 2010, new york state (nys) made major changes to its hiv testing law to come more closely into compliance with 2006 recommendations of the centers for disease control and prevention. because of the size and severity of the epidemic in nys, the strong public health response, and powerful advocacy community, the state had early on enacted strict rules around all aspects of hiv testing. between 2006 and 2010, 12 distinct legislative proposals were advanced to modernize nys's approach, leading ul ... | 2015 | 25545494 |
| prisoners treated for hepatitis c with protease inhibitor, new york, usa, 2012. | 2015 | 25531029 | |
| hepatitis c surveillance among youth and young adults in new york city, 2009-2013. | increases in prescription opioid misuse, injection drug use, and hepatitis c infections have been reported among youth and young adults in the usa, particularly in rural and suburban areas. to better understand these trends in new york city and to characterize demographics and risk factors among a population who, by virtue of their age, are more likely to be recently infected with hepatitis c, we analyzed routine hepatitis c surveillance data from 2009 to 2013 and investigated a sample of person ... | 2015 | 25450518 |
| characteristics and tb treatment outcomes in tb patients with viral hepatitis, new york city, 2000-2010. | literature surrounding the burden of and factors associated with hepatitis b virus (hbv) and hepatitis c virus (hcv) infection in persons with tuberculosis (tb) disease remains limited and focused on populations outside the usa. cross-matched new york city (nyc) tb and viral hepatitis surveillance data were used to estimate the proportion of nyc adults diagnosed with tb from 2000 to 2010 with a report of viral hepatitis infection and to describe the impact of viral hepatitis infection on tb trea ... | 2015 | 25387450 |
| duplicate hepatitis c antibody testing in new york city, 2006-2010. | repeating a hepatitis c virus antibody test for a person who previously tested positive provides no new information, wastes resources, and may reflect poor coordination of medical care. using public health surveillance data collected by the new york city department of health and mental hygiene, we evaluated the magnitude of duplicate antibody testing and assessed patient-level and facility-level risk factors for duplicate testing. from 2006 to 2010, 70,257 duplicate tests were performed for 58,8 ... | 2017 | 25364050 |
| detection of zoonotic pathogens and characterization of novel viruses carried by commensal rattus norvegicus in new york city. | norway rats (rattus norvegicus) are globally distributed and concentrate in urban environments, where they live and feed in closer proximity to human populations than most other mammals. despite the potential role of rats as reservoirs of zoonotic diseases, the microbial diversity present in urban rat populations remains unexplored. in this study, we used targeted molecular assays to detect known bacterial, viral, and protozoan human pathogens and unbiased high-throughput sequencing to identify ... | 2014 | 25316698 |
| risk factors for hcv infection among young adults in rural new york who inject prescription opioid analgesics. | we investigated a cluster of new hepatitis c cases in rural new york among a cohort of young people who inject drugs (pwid) and misuse prescription opioid analgesics (poa). | 2014 | 25211717 |
| prevalence and correlates of hepatitis c virus infection among inmates at two new york state correctional facilities. | previous studies have reported decreasing hepatitis c virus (hcv) infection rates in the general population. however, differential susceptibility in institutionalized populations suggest that hcv infection is even more prevalent in prison populations than previously reported yet, routine screening for hcv infection among prisoners is not generally available. we estimated the hcv prevalence and identified associated exposures at two maximum-security prisons using data obtained from 2788 inmates f ... | 2016 | 25182508 |
| hiv and viral hepatitis co-infection in new york city, 2000-2010: prevalence and case characteristics. | using surveillance data, we describe the prevalence and characteristics of individuals in new york city (nyc) co-infected with human immunodeficiency virus (hiv) and hepatitis b virus (hbv) and/or hepatitis c virus (hcv). surveillance databases including persons reported to the nyc department of health and mental hygiene with hiv, hbv, and hcv by 31 december 2010 and not known to be dead as of 1 january 2000, were matched with 2000-2011 vital statistics mortality data. of 140 606 persons reporte ... | 2015 | 25170631 |
| impact of repeat testing of living kidney donors within 14 days of the transplant procedure: a multicenter retrospective survey. | a transmission of human immunodeficiency virus (hiv) from a live kidney donor prompted recommendations by the new york state department of health and the us centers for disease control and prevention that all live donors undergo additional screening for hiv, hepatitis b virus (hbv), and hepatitis c virus (hcv) within 7-14 days of the donation procedure. there are concerns that re-screening will result in delays and cancelled transplants. | 2014 | 24796964 |
| deaths among people with hepatitis c in new york city, 2000-2011. | infection with hepatitis c virus (hcv) increases the risk of death from liver and nonliver-related diseases. coinfection with human immunodeficiency virus (hiv) further increases this risk. | 2014 | 24523215 |
| matching hiv, tuberculosis, viral hepatitis, and sexually transmitted diseases surveillance data, 2000-2010: identification of infectious disease syndemics in new york city. | in 2012, the new york city department of health and mental hygiene matched hiv, tuberculosis, viral hepatitis, and sexually transmitted disease surveillance data to identify the burden of infection with multiple diseases. | 2014 | 24335712 |
| enhanced chronic hepatitis c surveillance in new york city, april 2009-january 2011. | we analyzed and evaluated enhanced chronic hepatitis c virus (hcv) surveillance in new york city (nyc), which involved detailed investigations on a sample of newly reported hcv patients. | 2017 | 24179262 |
| prescription drug misuse and risk behaviors among young injection drug users. | prescription drug misuse among young adults, especially opioids, is a substantial public health problem in the united states. although risks associated with injection of illicit drugs are well established, injection and sexual risks associated with misuse of prescription drugs are under-studied. forty young injection drug users aged 16 to 25 who reported injection of a prescription drug were recruited in 2008-09 in los angeles and new york city. descriptive quantitative and qualitative data were ... | 2017 | 23908999 |
| hepatitis c screening beyond cdc guidelines in an egyptian immigrant community. | many egyptian-born persons in the u.s. are at high risk of chronic hepatitis c virus (hcv) infection, yet are not aware of their infection and lack healthcare coverage or linkage to care. in this study, we target egyptian-born persons living in the new york city area for screening and link to care. | 2014 | 23890188 |
| substance abuse treatment utilization, hiv risk behaviors, and recruitment among suburban injection drug users in long island, new york. | prevention and treatment of injection drug use remains a public health concern. we used data from the 2005 centers for disease control and prevention national hiv behavioral surveillance system to assess substance abuse treatment utilization, risk behaviors, and recruitment processes in a respondent driven sample of suburban injectors. twelve service utilization and injection risk variables were analyzed using latent class analysis. three latent classes were identified: low use, low risk; low us ... | 2014 | 23709253 |
| estimating the prevalence of hepatitis c infection in new york city using surveillance data. | hepatitis c virus is the most common chronic blood-borne infection in the usa. based on results of a serosurvey, national prevalence is estimated to be 1·3% or 3·2 million people. sub-national estimates are not available for most jurisdictions. hepatitis c surveillance data was adjusted for death, out-migration, under-diagnosis, and undetectable blood rna, to estimate prevalence in new york city (nyc). the prevalence of hepatitis c infection in adults aged ⩾20 years in nyc is 2·37% (range 1·53-4 ... | 2014 | 23657093 |
| managing adverse effects and complications in completing treatment for hepatitis c virus infection. | the addition of direct-acting antivirals (daas) to hepatitis c virus (hcv) treatment regimens has made treatment more effective and patient management more complex. shepherding patients through a full course of hcv therapy requires motivation and involvement on the part of the patient and the physician. indeed, physician inexperience and lack of confidence in guiding patients through the challenges of treatment appears to be a primary reason for early discontinuation of therapy. among the many c ... | 2012 | 23154251 |
| hepatitis c transmission due to contamination of multidose medication vials: summary of an outbreak and a call to action. | in may 2001, the new york city department of health and mental hygiene was informed of a cluster of 4 patients treated at an outpatient gastroenterology center who developed acute hepatitis c virus infection. an investigation identified a total of 12 clinic-associated hepatitis c virus transmissions and the outbreak and was traced to unsafe handling of multidose anesthetic vials and possible re-use of contaminated needles. this report typifies the types of outbreaks that continue to occur despit ... | 2013 | 22632822 |
| risk of hip fracture associated with hepatitis c virus infection and hepatitis c/human immunodeficiency virus coinfection. | hepatitis c virus (hcv) infection has been associated with reduced bone mineral density, but its association with fracture rates is unknown, particularly in the setting of human immunodeficiency virus (hiv) coinfection. our aims were to determine whether persons with hcv infection alone are at increased risk for hip fracture, compared to uninfected individuals, and to examine whether the risk of hip fracture is higher among hcv/hiv-coinfected persons, compared to those with hcv alone, those with ... | 2012 | 22619086 |
| investigation of viral hepatitis infections possibly associated with health-care delivery--new york city, 2008-2011. | hepatitis b virus (hbv) and hepatitis c virus (hcv) infections are important causes of morbidity and mortality in the united states. because hbv and hcv are transmitted efficiently percutaneously, possible transmission in health-care settings is of particular concern. public health investigations of cases of hbv and hcv infection suspected to be associated with health-care delivery play an essential role in identifying unsafe practices and controlling health-care-associated viral hepatitis trans ... | 2012 | 22592271 |
| advances in the treatment of hepatitis c virus infection. | since 2007, the annual age-adjusted mortality rate in hepatitis c virus (hcv) infection in the united states has been greater than that in hiv disease, reflecting the continuing decline in hiv-related mortality and the continuing increase in hcv-related mortality. the approval of 2 new direct-acting antivirals within the past year, as well as the promise offered by numerous other direct-acting agents in development, provides hope that we will be able to markedly improve our ability to cure hcv d ... | 2014 | 22538244 |
| case-control study of hepatitis b and hepatitis c in older adults: do healthcare exposures contribute to burden of new infections? | reports of hepatitis b virus (hbv) and hepatitis c virus (hcv) transmission associated with unsafe medical practices have been increasing in the united states. however, the contribution of healthcare exposures to the burden of new infections is poorly understood outside of recognized outbreaks. we conducted a case-control study at three health departments that perform enhanced viral hepatitis surveillance in new york and oregon. reported cases of symptomatic acute hepatitis b and hepatitis c occ ... | 2013 | 22383058 |
| correlates of staying safe behaviors among long-term injection drug users: psychometric evaluation of the staying safe questionnaire. | we report on psychometric properties of a new questionnaire to study long-term strategies, practices and tactics that may help injection drug users (idus) avoid infection with hiv and hepatitis c. sixty-two long-term idus were interviewed in new york city in 2009. five scales based on a total of 47 items were formed covering the following domains: stigma avoidance, withdrawal prevention, homeless safety, embedding safety within a network of users, and access to resources/social support. all scal ... | 2011 | 22038081 |
| sexual transmission of hepatitis c virus among hiv-infected men who have sex with men --- new york city, 2005--2010. | in the united states, an estimated 3.2 million persons are living with hepatitis c virus (hcv) infection. hcv transmission occurs primarily through percutaneous exposure to blood, and persons who inject drugs are at greatest risk for infection. the role of sexual transmission of hcv has not been well defined. however, reports over the past decade, mainly from europe, have implicated sexual transmission of hcv among human immunodeficiency virus (hiv)--infected men who have sex with men (msm). in ... | 2011 | 21775948 |
| unmet needs among people reported with hepatitis c, new york city. | : this project sought to describe unmet needs among patients reported with hepatitis c in new york city. | 2011 | 21617400 |
| associations between herpes simplex virus type 2 and hcv with hiv among injecting drug users in new york city. | objectives. we examined relationships between herpes simplex virus type 2 (hsv-2), a biomarker for sexual risk, and hcv, a biomarker for injecting risk, with hiv among injecting drug users (idus) who began injecting after large-scale expansion of syringe exchange programs in new york city. methods. we recruited 337 heroin and cocaine users who began injecting in 1995 or later from persons entering drug detoxification. we administered a structured interview covering drug use and hiv risk behavior ... | 2011 | 21566021 |
| hepatitis c treatment completion in individuals with psychiatric comorbidity and depression. | hepatitis c virus is a common bloodborne pathogen. patient, provider, and health care system factors combine to constrain access to treatment and have led to low rates of treatment initiation and continuation among medically eligible individuals. behavioral health comorbidity, which is common in the patient population, has historically been an exclusion criterion and is one such barrier to care. we implemented an interdisciplinary nurse-managed primary care-based hepatitis c evaluation and treat ... | 2011 | 21455042 |
| symbiotic goals and the prevention of blood-borne viruses among injection drug users. | a positive-deviance control-case life history study of injection drug users (idus) in new york city who had injected drugs for 8-15 years compared 21 idus who were antibody negative for both hiv and hepatitis c with 3 infected with both viruses and 11 infected with hepatitis c virus but not hiv. eligible subjects were referred from other research studies and from community organizations that conduct testing for hiv and hepatitis c virus. data were collected during 2005-2008 and were analyzed usi ... | 2011 | 21303250 |
| incident hepatitis c virus infection among us hiv-infected men enrolled in clinical trials. | outbreaks of sexually transmitted hepatitis c virus (hcv) infection have been reported among human immunodeficiency virus (hiv)-infected men who have sex with men in europe, australia, and new york. whether this is occurring across the united states is unknown. | 2011 | 21282184 |
| syringe exchange programs --- united states, 2008. | persons who inject drugs should use a new, sterile needle and syringe for each injection. syringe exchange programs (seps) provide free sterile syringes and collect used syringes from injection-drug users (idus) to reduce transmission of bloodborne pathogens, including human immunodeficiency virus (hiv), hepatitis b virus, and hepatitis c virus (hcv). as of march 2009, a total of 184 seps were known to be operating in 36 states, the district of columbia (dc), and puerto rico (north american syri ... | 2010 | 21085091 |
| steatohepatitic hepatocellular carcinoma (sh-hcc): a distinctive histological variant of hcc in hepatitis c virus-related cirrhosis with associated nafld/nash. | in explant livers with chronic hepatitis c (hcv-c) we have noted a distinctive histologic variant that we have termed steatohepatitic hepatocellular carcinoma (sh-hcc) with features resembling non-neoplastic steatohepatitis, including large droplet steatosis, ballooning of malignant hepatocytes, mallory-denk bodies, inflammation, and pericellular fibrosis. this study was undertaken to further describe the characteristics and prevalence of this histologic variant in hcv-c and any possible associa ... | 2010 | 20975341 |
| hiv and hcv health beliefs in an inner-city community. | summary. chronic infection with the hepatitis c virus (hcv) is more prevalent than human immunodeficiency virus (hiv) infection, but more public health resources are allocated to hiv than to hcv. given shared risk factors and epidemiology, we compared accuracy of health beliefs about hiv and hcv in an at-risk community. between 2002 and 2003, we surveyed a random patient sample at a primary care clinic in new york. the survey was organized as domains of common sense model of self-regulation: ca ... | 2010 | 20950406 |
| major adverse cardiac events in patients with hepatitis c infection treated with bare-metal versus drug-eluting stents. | there are no data comparing the long-term outcome of bare-metal stents (bms) vs drug-eluting stents (des) in patients with hepatitis c virus (hcv) infection. | 2010 | 20556808 |
| hepatitis c in an urban cohort: who's not being treated? | hepatitis c virus (hcv) remains widely prevalent in the u.s. treatment has improved, but rates of treatment initiation remain low. we sought to identify clinical and sociodemographic characteristics of patients that are associated with failure to initiate treatment of hcv infection. we conducted a retrospective cohort study in our primary care hepatitis c treatment clinic, affiliated with an urban academic hospital. our population was multi-ethnic, hiv-, hcv+, treatment naïve patients. we measur ... | 2009 | 20168019 |
| hepatitis b virus infection among american patients with chronic hepatitis c virus infection: prevalence, racial/ethnic differences, and viral interactions. | little is known about hepatitis b virus (hbv) infection among patients with chronic hepatitis c virus (hcv) infection in the united states. we prospectively enrolled 1,257 patients with chronic hcv infection from two medical centers in new york city. a total of 61.5% (95% confidence interval, 58.8%-64.2%) had evidence of prior exposure to hbv (hepatitis b core antibody-positive), whereas 5.8% (95% confidence interval, 4.5%-7.1%) had dual infection with hbv (hepatitis b surface antigen-positive). ... | 2010 | 20140950 |
| prevalence of hepatitis c infection in new york city, 2004. | hepatitis c virus (hcv) is the leading cause of chronic liver disease in the united states. accurate hepatitis c prevalence estimates are important to guide local public health programs but are usually unavailable to local health jurisdictions. national surveys may not reflect local variation, a particular challenge for urban settings with disproportionately large numbers of residents in high-risk population groups. in 2004, the new york city department of health and mental hygiene conducted the ... | 2009 | 19672718 |
| hepatitis c virus transmission at an outpatient hemodialysis unit--new york, 2001-2008. | in july 2008, the new york state department of health (nysdoh) received reports of three hemodialysis patients seroconverting from anti-hepatitis c virus (hcv) negative to anti-hcv positive in a new york city hemodialysis unit during the preceding 6 months. nysdoh conducted patient interviews and made multiple visits to the hemodialysis unit to observe hemodialysis treatments, assess infection control practices, evaluate hcv surveillance activities, review medical records, and conduct interviews ... | 2009 | 19265779 |
| risky sexual behavior, bleeding caused by intimate partner violence, and hepatitis c virus infection in patients of a sexually transmitted disease clinic. | we sought to investigate independent contributions of risky sexual behaviors and bleeding caused by intimate partner violence to prediction of hcv infection. | 2009 | 19218181 |
| using hepatitis c virus and herpes simplex virus-2 to track hiv among injecting drug users in new york city. | to explore the potential utility of hepatitis c virus (hcv) seroprevalence as a biomarker for injection risk, and herpes simplex virus-2 (hsv-2) as a biomarker for sexual risk among injecting drug users (idus). we examined the relationships between hcv and hiv and between hsv-2 and hiv among injecting drug users in new york city relative to the large-scale implementation of syringe exchange in the mid-1990s. | 2009 | 19108958 |
| co-infection of hepatitis b and hepatitis c virus in human immunodeficiency virus-infected patients in new york city, united states. | to study the prevalence and risk factors associated with triple infection with human immunodeficiency virus (hiv)/hepatitis b virus (hbv)/hepatitis c virus (hcv) in an urban clinic population. | 2008 | 19034972 |
| validation of a hepatitis c screening tool in primary care. | although hepatitis c virus (hcv) has an estimated national prevalence of 1.8%, testing rates are lower than those recommended by guidelines, particularly in primary care. a critical step is the ability to identify patients at increased risk who should be screened. we sought to prospectively derive and validate a clinical predication tool to assist primary care providers in identifying patients who should be tested for hcv antibodies. | 2008 | 18852403 |
| use of enhanced surveillance for hepatitis c virus infection to detect a cluster among young injection-drug users--new york, november 2004-april 2007. | infection with hepatitis c virus (hcv) is a leading cause of chronic liver disease in the united states. chronic hepatitis b and c virus infections were added to the nationally notifiable diseases list in 2003. approximately 3.2 million persons in the united states have chronic hcv infection. the most common risk factor for hcv infection is illicit drug use (specifically injection-drug use [idu]), although approximately one third to one half of cases have no identified risk factor. because appro ... | 2008 | 18480744 |
| prevalence of hepatitis c virus infection among injection drug users in the united states, 1994-2004. | to examine hepatitis c virus (hcv) seroprevalence among injection drug users in 4 us cities from 1994 through 2004. | 2008 | 18462109 |
| high prevalence of hepatitis c virus infection among immigrants from the former soviet union in the new york city metropolitan area: results of a community-based screening program. | inadequate sterilization and reuse of medical equipment likely contributed to hepatitis c virus (hcv) transmission in the former soviet union (fsu). although new york leads the nation in the number of immigrants from the fsu, the epidemiology of hcv infection has not been evaluated in this population. the aims of this study were to determine the prevalence of and risk factors for hcv infection among immigrants from the fsu in the new york metropolitan area. | 2008 | 18397420 |
| positive deviance control-case life history: a method to develop grounded hypotheses about successful long-term avoidance of infection. | prevalence rates for long-term injection drug users in some localities surpass 60% for hiv and 80% for hcv. we describe methods for developing grounded hypotheses about how some injectors avoid infection with either virus. | 2008 | 18366699 |
| greater drug injecting risk for hiv, hbv, and hcv infection in a city where syringe exchange and pharmacy syringe distribution are illegal. | comparing drug-injecting risk between cities that differ in the legality of sterile syringe distribution for injection drug use provides a natural experiment to assess the efficacy of legalizing sterile syringe distribution as a structural intervention to prevent human immunodeficiency virus (hiv) and other parenterally transmitted infections among injection drug users (idus). this study compares the parenteral risk for hiv and hepatitis b (hbv) and c (hcv) infection among idus in newark, nj, us ... | 2008 | 18340537 |
| markers for hepatitis a, b and c in methadone maintained patients: an unexpectedly high co-infection with silent hepatitis b. | to determine the prevalence of hepatitis a, b and c viruses in patients attending a methadone maintenance clinic in new york city. | 2008 | 18339114 |
| can urban methadone patients complete health utility assessments? | to assess the ability of methadone maintenance treatment (mmt) patients to use two standardized health assessment tools to value health states related to chronic hepatitis c virus (hcv) infection and hcv treatment-associated side effects. an estimated 65-90% of mmt patients are chronically infected with hcv. | 2008 | 18314295 |
| chronic kidney disease in hiv infection: an urban epidemic. | kidney disease is an important complication of hiv, particularly in minority populations. we describe the burden of chronic kidney disease among 1239 adults followed at an urban aids center, with an estimated prevalence of 15.5% (n = 192). independent predictors of kidney disease included older age, black race, hepatitis c virus exposure, and lower cd4 cell count. these data suggest that chronic kidney disease remains a common complication of hiv infection in the era of antiretroviral therapy. | 2007 | 17885301 |
| integrating multiple programme and policy approaches to hepatitis c prevention and care for injection drug users: a comprehensive approach. | new york state is home to an estimated 230,000 individuals chronically infected with hepatitis c virus (hcv) and roughly 171,500 active injection drug users (idus). hcv/hiv co-infection is common and models of service delivery that effectively meet idus' needs are required. a hcv strategic plan has stressed integration. | 2007 | 17854731 |
| how can hepatitis c be prevented in the long term? | significant advances have been made in preventing hiv infection among injectors but we still know little about preventing hepatitis c (hcv). both prevalence and incidence of hepatitis c can remain high among idus even in the context of widespread implementation of harm reduction programmes. we need to develop new ways to fill the knowledge gap regarding hcv prevention. one way is to learn from the experts--those idus who, after long-term injection in social milieus of high hepatitis c prevalence ... | 2007 | 17854720 |
| effects of a brief educational program on knowledge and willingness to accept treatment among patients with hepatitis c at inner-city hospitals. | hepatitis c is the most common cause of chronic liver disease in the united states. the prevalence of hcv infection is higher in african americans and hispanics than among non-hispanic whites. african americans not only have a high prevalence of hcv but they also show lower response rates to treatment with pegylated interferon and ribavirin. studies have shown that hcv patients often have low levels of knowledge about the disease, including knowledge about modes of transmission and available tre ... | 2007 | 17696047 |
| rapidly progressing hepatitis c in new york gay men. new surveillance networks needed. | 2007 | 17569166 | |
| chronic hepatitis c virus and celiac disease, is there an association? | celiac disease (cd) has been epidemiologically associated with chronic hepatitis c (hcv), and cd activation after the initiation of interferon (ifn-alpha) in patients with hcv is documented. however, clear association of cd and hcv is lacking. a prospectively maintained database of 878 cd patients showed a prevalence of 0.68% (six patients). symptoms of diarrhea, weight loss, and depression prompted the diagnosis of cd during or after ifn-alpha therapy in four cases. also, 294 subjects with live ... | 2008 | 17549632 |
| promoting hcv treatment completion for prison inmates: new york state's hepatitis c continuity program. | this article describes the development of a statewide program providing continuity of hepatitis c virus (hcv) treatment to prisoners upon release to the community. we discussed length of stay as a barrier to treatment with key collaborators; developed protocols, a referral process, and forms; mobilized staff; recruited heath-care facilities to accept referrals; and provided short-term access to hcv medications for inmates upon release. the hepatitis c continuity program, including 70 prisons and ... | 2007 | 17542460 |
| does integrating viral hepatitis services into a public std clinic attract injection drug users for care? | injection drug users (idus) are at high risk for multiple health problems, including human immunodeficiency virus (hiv), viral hepatitis, and sexually transmitted diseases (stds), and are likely to have poor access to health care. to more effectively serve high-risk clients, experts recommend that programs accessed by such client populations offer integrated services. in 2000, the new york city department of health and mental hygiene integrated viral hepatitis services (vaccine and screening) in ... | 2007 | 17542450 |
| correlates of drug treatment program staff's self efficacy to support their clients' hepatitis c virus (hcv) related needs. | drug treatment staff are uniquely situated to support their clients' hcv related needs, and those with greater self efficacy to do so are more likely to provide this support. using data collected from staff (n = 140) in 6 drug treatment programs in new york city, we determined the correlates of this self efficacy. results indicate that medically credentialed staff and staff with more hepatitis c knowledge have greater self efficacy to support their clients' hcv related needs. there was no relati ... | 2007 | 17497547 |
| individual and couple-level risk factors for hepatitis c infection among heterosexual drug users: a multilevel dyadic analysis. | hepatitis c virus (hcv) is the most common bloodborne pathogen in the united states and is a leading cause of liver-related morbidity and mortality. although it is known that hcv is most commonly transmitted among injection drug users, the role of sexual transmission in the spread of hcv remains controversial because of inconsistent findings across studies involving heterosexual couples. | 2007 | 17471426 |
| offers of hepatitis c care do not lead to treatment. | since 2002, clinicians have been encouraged to offer chronic hepatitis c virus (hcv) treatment to patients with injection drug use histories. we conducted 69 baseline and 35 follow-up interviews between september 2002 and november 2004 with hcv patients who were treatment-naïve and receiving regular medical care at an hiv or methadone clinic in new york city at baseline. of the 31 patients reinterviewed, 20 (65%) were offered treatment but only 2 (7%) were treated. reasons for failure to be rein ... | 2007 | 17394085 |
| sexual and other noninjection risks for hbv and hcv seroconversions among noninjecting heroin users. | many heroin users do not inject drugs but may still be at risk of infection with human immunodeficiency virus (hiv), hepatitis b virus (hbv), and hepatitis c virus (hcv), via sexual or other noninjection-related activity. | 2007 | 17330797 |
| injecting and sexual risk correlates of hbv and hcv seroprevalence among new drug injectors. | we examine injecting and sexual risk correlates of hepatitis b (hbv) and hepatitis c (hcv) seroprevalence among new injecting drug users (idus) (age 18-30 years, injecting < or =6 years). participants were interviewed/serotested (hivab, hbvcab, hcvab) in new york city, february 1999-february 2003. gender-stratified, multivariate logistic regression was conducted. participants (n=259) were: 68% male; 81% white. women were more likely to test hcv seropositive (42% versus 27%) and men hbv seroposit ... | 2007 | 17289298 |
| self-reported hepatitis c virus antibody status and risk behavior in young injectors. | this study was conducted to assess the accuracy of self-reported hepatitis c virus (hcv) antibody (anti-hcv) serostatus in injection drug users (idus), and examine whether self-reported anti-hcv serostatus was associated with recent injection risk behavior. | 2006 | 17278406 |
| hepatitis c knowledge among staff in u.s. drug treatment programs. | staff in drug treatment programs are in an optimal position to support the hepatitis c related needs of their patients. to do so effectively, however, staff need to have accurate information about the hepatitis c virus (hcv). this article examines the hcv knowledge of staff (n= 104) in two drug-free and two methadone maintenance treatment programs (mmtps) in the new york metropolitan area. five of 20 items on an hcv knowledge assessment were not answered correctly by the majority of the particip ... | 2006 | 17153514 |
| a study of low dose peginterferon alpha-2b with ribavirin for the initial treatment of chronic hepatitis c. | a prospective randomized trial was undertaken to test the efficacy of low and standard doses of pegylated interferon alpha-2b in combination with ribavirin for the initial treatment of chronic hepatitis c. by nature of its design the study also provided data on response to therapy over a spectrum of doses of both pegylated interferon alpha-2b and ribavirin calculated on a body weight basis. | 2006 | 16771948 |
| analysis of a hepatitis c screening programme for us veterans. | this study analyses a screening programme for hepatitis c virus (hcv) infection among us veterans in a suburban veterans affairs medical center, in new york. this is the first study examining all 11 potential risk factors listed in the 2001 national u.s. veterans health administration screening guidelines. a retrospective study was conducted of 5400 veterans 'at risk' of hcv, identified through a questionnaire in this institution's primary-care outpatient departments between 1 october 2001 and 3 ... | 2006 | 16490127 |
| liver transplantation for hepatitis b in the united states. | to evaluate the impact of hepatitis b virus (hbv) on us health care system, we reviewed the organ procurement and transplantation (optn, formerly unos) hbv database. | 2005 | 16387118 |
| reductions in hepatitis c virus and hiv infections among injecting drug users in new york city, 1990-2001. | to assess trends in hiv, hepatitis c virus (hcv) and hiv/hcv infection among injecting drug users (idu) from 1990 to 2001 in new york city. the 1990-2001 time period included a very large expansion of syringe exchange in new york city, from 250,000 to 3,000,000 syringes exchanged annually. | 2005 | 16251819 |
| high prevalence of alcohol use among hepatitis c virus antibody positive injection drug users in three us cities. | injection drug users (idus) acquire the majority of new hepatitis c virus (hcv) infections and frequently use alcohol. alcohol abuse accelerates liver disease among hcv-infected persons, can reduce the effectiveness of treatment for hcv infection and may be a contraindication for hcv treatment. hcv seropositive, hiv-negative idus aged 18-35 years in baltimore, new york city and seattle who were enrolled in a behavioral risk-reduction intervention trial underwent computerized self-interviews to a ... | 2006 | 16129567 |
| association of sex, hygiene and drug equipment sharing with hepatitis c virus infection among non-injecting drug users in new york city. | hepatitis c virus (hcv) rates are higher in non-injecting drug users (nidus) than general population estimates. whether this elevated hcv rate is due to drug use or other putative risk behaviors remains unclear. | 2005 | 16102381 |
| integrating services for injection drug users infected with hepatitis c virus with methadone maintenance treatment: challenges and opportunities. | despite the high prevalence of hepatitis c virus (hcv) infection among drug users enrolled in methadone maintenance treatment programs, few drug users are being treated with combination therapy. the most significant barrier to treatment is lack of access to comprehensive hcv-related care. we describe a pilot program to integrate care for hcv infection with substance abuse treatment in a setting of maintenance treatment with methadone. this on-site, multidisciplinary model of care includes compre ... | 2005 | 15768345 |
| factors associated with interest in initiating treatment for hepatitis c virus (hcv) infection among young hcv-infected injection drug users. | we sought to identify factors associated with interest in receiving therapy for hepatitis c virus (hcv) infection among hcv-infected injection drug users (idus) in 3 united states cities. | 2005 | 15768339 |
| estimating the mortality rate of hepatitis c using multiple data sources. | the new york state hospital discharge database and the multiple cause-of-death file were used to estimate the mortality rate of hepatitis c in new york state excluding new york city in 1997. the mortality rate with hepatitis c was severely underestimated when each data source was used alone. applying the capture recapture method using the hospital discharge database and the multiple cause-of-death file appears to be an efficient method to estimate the mortality rate with hepatitis c. | 2005 | 15724719 |
| sharing of noninjection drug-use implements as a risk factor for hepatitis c. | this study examined sharing noninjection drug implements as a risk factor for hepatitis c (hcv) infection among women drug users (n = 123) with no history of drug injection. participants were street-recruited from east harlem, new york city, between october 1997 and june 1999. participants were administered a survey measuring risk factors for hcv. prevalence of hcv and hiv infections was 19.5% and 14.6%, respectively. multiple logistic regression determined significant associations between shari ... | 2004 | 15061559 |
| hepatitis c incidence--a comparison between injection and noninjection drug users in new york city. | hepatitis c virus (hcv) burdens injection drug users (idus) with prevalence estimated from 60-100% compared to around 5% among noninjection drug users (non-idus). we present preliminary data comparing the risk for hcv among idus and non-idus to inform new avenues of hcv prevention and intervention planning. two cohorts, new idus (injecting < or =3 years) and non-idus (smoke/sniff heroine, crack or cocaine < or =10 years), ages 15-40, were street-recruited in new york city. participants underwent ... | 2004 | 15047780 |
| transmission of hepatitis b and c viruses in outpatient settings--new york, oklahoma, and nebraska, 2000-2002. | transmission of hepatitis b virus (hbv) and hepatitis c virus (hcv) can occur in health-care settings from percutaneous or mucosal exposures to blood or other body fluids from an infected patient or health-care worker. this report summarizes the investigation of four outbreaks of hbv and hcv infections that occurred in outpatient health-care settings. the investigation of each outbreak suggested that unsafe injection practices, primarily reuse of syringes and needles or contamination of multiple ... | 2003 | 14508437 |
| the association of hepatitis c prevalence, activity, and genotype with hiv infection in a cohort of new york city drug users. | factors associated with serum hcv antibody, hcv rna level, and hcv genotype were assessed in 557 current and former drug users. additional assays included hiv antibody, cd4+ lymphocyte counts, hiv viral loads, and hepatitis b markers. seventy-five percent of subjects were anti-hcv positive, of whom 75% had detectable hcv rna (median, 5.04 x 10(5) iu/ml; range, 1020-15.7 x 10(6)). on multivariate analysis hcv seropositivity was associated with history of drug injection, hiv seropositivity, and in ... | 2003 | 12843747 |
| colonoscopes may spread hcv and hpv. | 2003 | 12825588 |