Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| epstein-barr virus serology as a potential screening marker for nasopharyngeal carcinoma among high-risk individuals from multiplex families in taiwan. | nasopharyngeal carcinoma (npc) is an epstein-barr virus (ebv)-associated cancer that is highly treatable when diagnosed early, with 5-year disease-free survival of approximately 90%. however, npc is typically diagnosed at advanced stages, in which disease-free survival is <50%. there is, therefore, a need for clinical tools to assist in early npc detection, particularly among high-risk individuals. | 2014 | 24769890 |
| spectrum of epstein-barr virus-associated t-cell lymphoproliferative disorder in adolescents and young adults in taiwan. | epstein-barr virus (ebv) is a herpesvirus usually infecting b-cells but may occasionally infect t- or natural killer (nk)-cells. ebv-associated t- or nk-cell lymphoproliferations represent a continuous spectrum of diseases ranging from asymptomatic infection, infectious mononucleosis (im), to clonal and malignant lymphoproliferations including systemic ebv-positive t/nk-cell lymphoproliferative disease (ebv-t/nk-lpd) of childhood and hydroa-vacciniforme-like lymphoma of the skin. the clonal dise ... | 2014 | 24966953 |
| prevalence of human papillomavirus and epstein-barr virus in salivary gland diseases. | the roles of human papillomavirus (hpv) and epstein-barr virus (ebv) in head and neck neoplasms have been well reported, but little is known about their relationship with salivary gland tumours. this study investigated the presence of hpv and ebv in salivary gland diseases. | 2014 | 25136053 |
| clinical characteristics and treatment outcome in a taiwanese population of patients with epstein-barr virus-positive diffuse large b-cell lymphoma. | epstein-barr virus-positive diffuse large b-cell lymphoma is a provisional entity in the 2008 world health organization classification of tumors of hematopoietic and lymphoid tissues. reports on the characteristics and clinical outcome of this disease in different geographic regions showed great disparities. | 2014 | 25320341 |
| angioimmunoblastic t-cell lymphoma in taiwan shows a frequent gain of itk gene. | angioimmunoblastic t-cell lymphoma (aitl) is an aggressive peripheral t-cell lymphoma (ptcl) of follicular helper t-cell origin and is rare in taiwan. there are overlapping features of aitl and peripheral t-cell lymphoma with a follicular growth pattern (ptcl-f). around one fifth of ptcl-f exhibits t(5;9)(q33;q22)/itk-syk chromosomal translocation, which is essentially absent in aitl. we retrospectively investigated 35 cases of aitl from taiwan with histopathology review, immunohistochemistry, i ... | 2014 | 25337257 |
| extranodal natural killer/t-cell lymphoma, nasal type in taiwan: a relatively higher frequency of t-cell lineage and poor survival for extranasal tumors. | extranodal natural killer (nk)/t-cell lymphoma, nasal type, is a predominantly extranodal lymphoma associated with epstein-barr virus occurring most frequently in the upper aerodigestive tract. there are limited reports on cellular origin and prognostic factors. we retrospectively investigated 73 cases with a median age of 54 years and a male-female ratio of 2.0:1. the upper aerodigestive tract (nasal group) was the most common site of involvement (51 cases; 70%). the other organs (n = 22; extra ... | 2015 | 25554090 |
| a large-scale seroprevalence of epstein-barr virus in taiwan. | epstein-barr virus (ebv) causes a variety of clinical manifestations from asymptomatic infection to acute infectious mononucleosis in human. moreover, the ebv infection is associated with malignancies. the large-scale ebv seroepidemiology across all age groups has been lacking in taiwan. | 2015 | 25615611 |
| clinical analysis of fever of unknown origin in children: a 10-year experience in a northern taiwan medical center. | fever of unknown origin (fuo) was first described in 1961 as fever >38.3°c for at least 3 weeks with no apparent source after 1 week of investigations in the hospital. infectious disease comprises the majority of cases (40-60%). there is no related research on fuo in children in taiwan. the aim of this study is to determine the etiologies of fuo in children in taiwan and to evaluate the relationship between the diagnosis and patient's demography and laboratory data. | 2017 | 25735796 |
| primary intestinal diffuse large b-cell lymphoma in taiwan showed a relative higher rate of perforation and ebv association. | we retrospectively investigated 59 surgically resected primary intestinal diffuse large b-cell lymphomas (pi-dlbcl) including 31 males and 28 females with a median age of 66. eleven (19%) tumors were perforated at presentation; 8 (14%) were multicentric. ileum (n=24; 43%) and ileocecum (n=17; 30%) were most frequently involved. twenty-one (36%) patients did not receive chemotherapy or radiotherapy including 6 with perforation and died in 0.2 to 7 months. the 1-, 2-, and 5-year overall survival r ... | 2016 | 26258754 |
| ebv-associated burkitt lymphoma in taiwan is not age-related. | this study retrospectively investigated 54 cases of sporadic burkitt lymphoma in taiwan with histopathology review, immunohistochemistry, epstein-barr virus (ebv) in situ hybridization (eber) and fluorescence in situ hybridization (fish). the great majority revealed typical immunophenotype and 89% (47/53) cases expressed myc protein. eber was positive in 20% (11/54) of cases, more frequently with nodal presentation, but not significantly associated with age (pediatric vs. adult), abdominal vs. e ... | 2016 | 26422188 |
| a review of nationwide population study of organ transplantation in taiwan. | solid organ transplantation has become the therapy of choice for patients with end-stage organ disease. the frequently transplanted organs in taiwan include liver, kidney, heart, and lung, and the success rate has improved significantly worldwide for the past decades. however, organ recipients are known to be at a higher risk of post-transplant infections and de novo cancer due to immunosuppression and oncogenic viral infections. organ recipients are known to be at a two- to fourfold increased r ... | 2016 | 27289565 |
| birth order and risk of nasopharyngeal carcinoma in multiplex families from taiwan. | a small proportion of individuals infected with epstein-barr virus (ebv) develop nasopharyngeal carcinoma (npc). timing of initial exposure could alter immunological responses to primary ebv infection and explain variation in cancer risk later in life. we measured early life family structure as a proxy for the timing of primary ebv infection to examine whether earlier age at infection alters npc risk. we utilized data from 480 npc cases and 1,291 unaffected siblings from taiwanese npc multiplex ... | 2016 | 27537611 |
| metformin and esophageal cancer risk in taiwanese patients with type 2 diabetes mellitus. | this study evaluated whether metformin might reduce esophageal cancer risk. patients with type 2 diabetes mellitus diagnosed during 1999-2005 were recruited from the reimbursement database of taiwan's national health insurance. those newly treated with metformin (n = 288013, "ever users of metformin") or other antidiabetic drugs (n = 16216, "never users of metformin") were followed until december 31, 2011. sensitivity analyses were conducted in a matched-pair sample of 16216 never users and 1621 ... | 2016 | 27861146 |
| evaluation of nasal and nasopharyngeal swab collection for the detection of epstein-barr virus in nasopharyngeal carcinoma. | ebv detection using nasopharyngeal swabs has been suggested as a potential screening test that could improve the specificity of current ebv-based serological assays. however, application requires insertion of the swab deep into the nasopharynx, a procedure not amenable to non-clinic screening. we reasoned that swabbing the more easily accessible nasal cavity might provide an appealing alternative for npc detection. | 2017 | 28833336 |